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Overview

ID MAG03244
Name PYH3_bin.54
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAKOQB01
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 0.5
GC content (%) 65.0
N50 (bp) 16,635
Genome size (bp) 4,190,291

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4087

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1011711_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 514.0
PYH3_k127_1011711_1 CoA-transferase family III - - - 0.000000000000000005008 85.0
PYH3_k127_1108993_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 397.0
PYH3_k127_1144559_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.621e-314 970.0
PYH3_k127_1144559_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.542e-223 702.0
PYH3_k127_1144559_10 Tim44 - - - 0.000000000000000000000000000000000000000000000006473 180.0
PYH3_k127_1144559_11 - - - - 0.00000000000000000000000000000000000000357 160.0
PYH3_k127_1144559_12 PFAM Sterol-binding domain protein K03690 - - 0.00000000000000000000000000000004524 133.0
PYH3_k127_1144559_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 555.0
PYH3_k127_1144559_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 504.0
PYH3_k127_1144559_4 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 396.0
PYH3_k127_1144559_5 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 392.0
PYH3_k127_1144559_6 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 365.0
PYH3_k127_1144559_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 365.0
PYH3_k127_1144559_8 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000000004113 206.0
PYH3_k127_1144559_9 Thiopurine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000003374 191.0
PYH3_k127_1157605_0 type II restriction enzyme, methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
PYH3_k127_1157605_1 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000001714 157.0
PYH3_k127_1157605_2 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000001197 145.0
PYH3_k127_1157605_3 Mut7-C RNAse domain - - - 0.0000000000000000000000000000000008315 132.0
PYH3_k127_1157605_4 type II restriction enzyme, methylase - - - 0.000000000000000000000000000000001181 134.0
PYH3_k127_1157605_5 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000004352 126.0
PYH3_k127_1157605_6 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000008604 116.0
PYH3_k127_1157605_7 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.00000000000000000000001475 107.0
PYH3_k127_1157605_8 Protein conserved in bacteria - - - 0.000000000000000000000517 96.0
PYH3_k127_1157605_9 - - - - 0.0002967 48.0
PYH3_k127_1220200_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.805e-272 846.0
PYH3_k127_1220200_1 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.564e-252 784.0
PYH3_k127_1220200_2 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 1.329e-211 664.0
PYH3_k127_1220200_3 Aldehyde dehydrogenase family K15514 - 1.2.1.77 8.181e-200 635.0
PYH3_k127_1220200_4 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 505.0
PYH3_k127_1220200_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 385.0
PYH3_k127_1220200_6 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000003791 211.0
PYH3_k127_1220200_7 acyl-CoA dehydrogenase - - - 0.00000000674 64.0
PYH3_k127_1238445_0 5'-nucleotidase, C-terminal domain K11751,K17224 - 3.1.3.5,3.6.1.45 9.563e-295 912.0
PYH3_k127_1238445_1 PUA-like domain K00958 - 2.7.7.4 4.469e-217 682.0
PYH3_k127_1238445_10 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005915 248.0
PYH3_k127_1238445_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005656 255.0
PYH3_k127_1238445_12 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005151 242.0
PYH3_k127_1238445_13 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000004747 195.0
PYH3_k127_1238445_14 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000005164 168.0
PYH3_k127_1238445_15 oxidation protein K17227 - - 0.00000000000000000000000000000000000000007954 153.0
PYH3_k127_1238445_16 Peptidase S24-like - - - 0.0000000000000000000000000000000003306 136.0
PYH3_k127_1238445_17 PFAM UspA domain protein K07090 - - 0.0000000000000000000000000000000007071 142.0
PYH3_k127_1238445_18 - - - - 0.0000000000000000000000000005212 124.0
PYH3_k127_1238445_19 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000004636 112.0
PYH3_k127_1238445_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 581.0
PYH3_k127_1238445_20 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000001166 113.0
PYH3_k127_1238445_21 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000009552 92.0
PYH3_k127_1238445_3 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 504.0
PYH3_k127_1238445_4 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 481.0
PYH3_k127_1238445_5 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 390.0
PYH3_k127_1238445_6 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 359.0
PYH3_k127_1238445_7 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 339.0
PYH3_k127_1238445_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
PYH3_k127_1238445_9 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 308.0
PYH3_k127_1239204_0 Extracellular ligand-binding receptor K01999 - - 1.286e-202 637.0
PYH3_k127_1239204_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 604.0
PYH3_k127_1239204_10 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003668 243.0
PYH3_k127_1239204_11 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000003058 222.0
PYH3_k127_1239204_12 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000003658 187.0
PYH3_k127_1239204_13 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000001329 162.0
PYH3_k127_1239204_14 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000000000002158 159.0
PYH3_k127_1239204_15 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000002749 143.0
PYH3_k127_1239204_16 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000006363 112.0
PYH3_k127_1239204_17 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000005159 70.0
PYH3_k127_1239204_18 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000002477 63.0
PYH3_k127_1239204_19 Transcriptional regulator K01719 - 4.2.1.75 0.0000001443 64.0
PYH3_k127_1239204_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 609.0
PYH3_k127_1239204_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 590.0
PYH3_k127_1239204_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 569.0
PYH3_k127_1239204_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 496.0
PYH3_k127_1239204_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 469.0
PYH3_k127_1239204_7 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 429.0
PYH3_k127_1239204_8 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 385.0
PYH3_k127_1239204_9 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
PYH3_k127_1250365_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
PYH3_k127_1250365_1 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 295.0
PYH3_k127_1250365_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000009369 70.0
PYH3_k127_1254136_0 plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000000002194 160.0
PYH3_k127_1254136_1 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000000005532 152.0
PYH3_k127_1254136_2 Transposase DDE domain - - - 0.0000000000000000000000001035 106.0
PYH3_k127_1274840_0 Virulence factor membrane-bound polymerase, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 306.0
PYH3_k127_1274840_1 Protein glycosylation ligase - - - 0.000000000000008662 78.0
PYH3_k127_1279691_0 Peptidase family M3 K01414 - 3.4.24.70 3.382e-275 865.0
PYH3_k127_1279691_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 534.0
PYH3_k127_1279691_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 470.0
PYH3_k127_1279691_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 391.0
PYH3_k127_1279691_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 353.0
PYH3_k127_1279691_5 helix_turn_helix, Lux Regulon K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002462 275.0
PYH3_k127_1279691_6 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000000000000007507 214.0
PYH3_k127_1279691_7 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000001029 139.0
PYH3_k127_1279691_8 PFAM Glutaredoxin - - - 0.00000000000000000000000000000000001757 146.0
PYH3_k127_1300856_0 PA domain - - - 6.058e-235 748.0
PYH3_k127_1300856_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003325 241.0
PYH3_k127_1300856_2 HEPN domain K09132 - - 0.0000000003628 68.0
PYH3_k127_1300856_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000001611 61.0
PYH3_k127_1315589_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.19e-294 922.0
PYH3_k127_1315589_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.481e-199 630.0
PYH3_k127_1315589_10 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000003537 77.0
PYH3_k127_1315589_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.499e-195 619.0
PYH3_k127_1315589_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 458.0
PYH3_k127_1315589_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 430.0
PYH3_k127_1315589_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 392.0
PYH3_k127_1315589_6 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 378.0
PYH3_k127_1315589_7 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001116 261.0
PYH3_k127_1315589_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009776 262.0
PYH3_k127_1315589_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000003752 144.0
PYH3_k127_1316097_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.128e-221 696.0
PYH3_k127_1316097_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 511.0
PYH3_k127_1316097_10 GNAT family acetyltransferase - - - 0.0001122 55.0
PYH3_k127_1316097_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
PYH3_k127_1316097_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 372.0
PYH3_k127_1316097_4 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 319.0
PYH3_k127_1316097_5 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000003231 219.0
PYH3_k127_1316097_6 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000009866 183.0
PYH3_k127_1316097_7 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000007157 178.0
PYH3_k127_1316097_8 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000005709 170.0
PYH3_k127_1326201_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 363.0
PYH3_k127_1326201_1 PFAM extracellular solute-binding protein family 1 K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 357.0
PYH3_k127_1326201_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000025 266.0
PYH3_k127_1328245_0 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 444.0
PYH3_k127_1328245_1 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.00000000000000000000000000000000836 130.0
PYH3_k127_1328245_2 Domain of unknown function (DUF1850) - - - 0.0000000000000005878 83.0
PYH3_k127_1336386_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.6e-206 649.0
PYH3_k127_1336386_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 464.0
PYH3_k127_1336386_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000004451 64.0
PYH3_k127_1339279_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
PYH3_k127_1339279_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
PYH3_k127_1339279_2 COG1132 ABC-type multidrug transport system, ATPase and permease components K18893 - - 0.00000000000000000000000000000000005552 138.0
PYH3_k127_1339279_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000001093 130.0
PYH3_k127_1339279_4 ABC transporter K06147,K18893 - - 0.0000000000000007507 81.0
PYH3_k127_1348235_0 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 436.0
PYH3_k127_1348235_1 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009901 238.0
PYH3_k127_1348235_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000001827 165.0
PYH3_k127_1349360_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 437.0
PYH3_k127_1349360_1 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 398.0
PYH3_k127_1364820_0 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000000000852 237.0
PYH3_k127_1364820_1 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.0000000000000000000000000000000003 138.0
PYH3_k127_1364820_2 Rubredoxin - - - 0.0000000000000000000000000000004779 124.0
PYH3_k127_1364820_3 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000000000000002453 87.0
PYH3_k127_1364820_4 Nickel-dependent hydrogenase - - - 0.000000000000005608 80.0
PYH3_k127_1392281_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 9.318e-235 743.0
PYH3_k127_1392281_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.158e-231 725.0
PYH3_k127_1392281_10 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000001639 138.0
PYH3_k127_1392281_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 604.0
PYH3_k127_1392281_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 468.0
PYH3_k127_1392281_4 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 460.0
PYH3_k127_1392281_5 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 379.0
PYH3_k127_1392281_6 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 305.0
PYH3_k127_1392281_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000125 185.0
PYH3_k127_1392281_8 Endoribonuclease L-PSP K10013 - - 0.000000000000000000000000000000000000000000000002094 177.0
PYH3_k127_1392281_9 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000009317 158.0
PYH3_k127_1403871_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001162 286.0
PYH3_k127_142129_0 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 436.0
PYH3_k127_142129_1 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 429.0
PYH3_k127_142129_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000009713 234.0
PYH3_k127_1438787_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.066e-265 827.0
PYH3_k127_1438787_1 Cytochrome b(N-terminal)/b6/petB - - - 1.375e-227 722.0
PYH3_k127_1438787_10 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000006232 179.0
PYH3_k127_1438787_11 - - - - 0.00000000000000000000000000000000000000004598 160.0
PYH3_k127_1438787_12 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000003074 126.0
PYH3_k127_1438787_13 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000001192 107.0
PYH3_k127_1438787_14 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.000000000000000000005086 93.0
PYH3_k127_1438787_15 PEP-CTERM motif - - - 0.00000000000000000003745 98.0
PYH3_k127_1438787_16 - - - - 0.0000000002066 65.0
PYH3_k127_1438787_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 518.0
PYH3_k127_1438787_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 430.0
PYH3_k127_1438787_4 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 327.0
PYH3_k127_1438787_5 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 291.0
PYH3_k127_1438787_6 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 295.0
PYH3_k127_1438787_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003613 286.0
PYH3_k127_1438787_8 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000001919 227.0
PYH3_k127_1438787_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000001323 184.0
PYH3_k127_1490875_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1e-266 827.0
PYH3_k127_1490875_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000001753 164.0
PYH3_k127_151588_0 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 332.0
PYH3_k127_151588_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000004144 102.0
PYH3_k127_151588_2 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000009004 81.0
PYH3_k127_151588_3 EamA-like transporter family K15270 - - 0.000001301 51.0
PYH3_k127_1554614_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 9.335e-231 724.0
PYH3_k127_1554614_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
PYH3_k127_1603194_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1142.0
PYH3_k127_1603194_1 Acyl-CoA dehydrogenase N terminal - - - 4.342e-277 862.0
PYH3_k127_1603194_10 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 381.0
PYH3_k127_1603194_11 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
PYH3_k127_1603194_12 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 333.0
PYH3_k127_1603194_13 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 323.0
PYH3_k127_1603194_14 cephalosporin hydroxylase K01190,K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002666 288.0
PYH3_k127_1603194_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005463 286.0
PYH3_k127_1603194_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 282.0
PYH3_k127_1603194_17 dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001268 271.0
PYH3_k127_1603194_18 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000004281 260.0
PYH3_k127_1603194_19 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009493 248.0
PYH3_k127_1603194_2 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.072e-272 851.0
PYH3_k127_1603194_20 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
PYH3_k127_1603194_21 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000001865 236.0
PYH3_k127_1603194_22 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000003829 215.0
PYH3_k127_1603194_23 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000005213 214.0
PYH3_k127_1603194_24 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000002553 198.0
PYH3_k127_1603194_25 spore germination - - - 0.00000000000000000000000000000000000000000000000000001418 200.0
PYH3_k127_1603194_26 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000007757 194.0
PYH3_k127_1603194_27 TraB family K09973 - - 0.0000000000000000000000000000000000000000000006281 177.0
PYH3_k127_1603194_28 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000000000002856 165.0
PYH3_k127_1603194_29 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000001073 166.0
PYH3_k127_1603194_3 CoA binding domain K09181 - - 9.733e-262 835.0
PYH3_k127_1603194_30 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000003429 167.0
PYH3_k127_1603194_31 hydrogenase maturation protease - - - 0.000000000000000000000000000000000006104 145.0
PYH3_k127_1603194_32 - - - - 0.0000000000000000000000000001236 123.0
PYH3_k127_1603194_33 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000009198 112.0
PYH3_k127_1603194_34 dksA traR - - - 0.0000000000000001097 85.0
PYH3_k127_1603194_35 protein conserved in bacteria - - - 0.00000000000000192 82.0
PYH3_k127_1603194_36 Cobalamin synthesis protein P47K - - - 0.0000005753 52.0
PYH3_k127_1603194_37 Transposase (IS116 IS110 IS902 family) - - - 0.000945 43.0
PYH3_k127_1603194_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.761e-250 779.0
PYH3_k127_1603194_5 Belongs to the thiolase family K00632 - 2.3.1.16 2.459e-204 641.0
PYH3_k127_1603194_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 495.0
PYH3_k127_1603194_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 447.0
PYH3_k127_1603194_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 444.0
PYH3_k127_1603194_9 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 398.0
PYH3_k127_1614147_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1016.0
PYH3_k127_1614147_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 2.309e-315 974.0
PYH3_k127_1614147_10 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
PYH3_k127_1614147_11 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000002085 190.0
PYH3_k127_1614147_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000008249 183.0
PYH3_k127_1614147_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000002828 184.0
PYH3_k127_1614147_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000001298 164.0
PYH3_k127_1614147_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000002341 143.0
PYH3_k127_1614147_16 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000001396 126.0
PYH3_k127_1614147_17 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000008336 111.0
PYH3_k127_1614147_18 Pfam:AmoA K07120 - - 0.0000000000000000000001052 101.0
PYH3_k127_1614147_19 ATP synthase I chain K02116 - - 0.000000000000001856 82.0
PYH3_k127_1614147_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.632e-280 867.0
PYH3_k127_1614147_20 Glucose / Sorbosone dehydrogenase - - - 0.0000000000005512 72.0
PYH3_k127_1614147_21 Ammonia monooxygenase K07120 - - 0.000003005 54.0
PYH3_k127_1614147_22 Protein involved in outer membrane biogenesis - - - 0.0002923 53.0
PYH3_k127_1614147_23 deiminase K05603 - 3.5.3.13 0.0006973 45.0
PYH3_k127_1614147_24 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0009538 45.0
PYH3_k127_1614147_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.263e-272 840.0
PYH3_k127_1614147_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 420.0
PYH3_k127_1614147_5 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 412.0
PYH3_k127_1614147_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 400.0
PYH3_k127_1614147_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 371.0
PYH3_k127_1614147_8 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 354.0
PYH3_k127_1614147_9 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
PYH3_k127_1619923_0 Belongs to the glycosyl hydrolase 13 family - - - 4.323e-284 882.0
PYH3_k127_1619923_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 614.0
PYH3_k127_1619923_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0000000000000000000000000000000000002706 143.0
PYH3_k127_1619923_3 Zn-ribbon protein possibly nucleic acid-binding - - - 0.0000000000000000000000000000000000003632 153.0
PYH3_k127_1630423_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 433.0
PYH3_k127_1630423_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 349.0
PYH3_k127_1630423_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000006527 180.0
PYH3_k127_1635796_0 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 420.0
PYH3_k127_1635796_1 PFAM transposase, mutator type K07493 - - 0.0000000000000000000000000000000000000000000000000000000000000000003132 229.0
PYH3_k127_1635796_2 Integrase core domain - - - 0.0000000000000000001533 91.0
PYH3_k127_1637513_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 424.0
PYH3_k127_1637513_1 RND efflux system, outer membrane lipoprotein K18139 - - 0.0000000000000000000008901 98.0
PYH3_k127_1657126_0 CoA-substrate-specific enzyme activase - - - 0.0 1970.0
PYH3_k127_1657126_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.215e-256 803.0
PYH3_k127_1657126_10 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 338.0
PYH3_k127_1657126_11 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 342.0
PYH3_k127_1657126_12 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 308.0
PYH3_k127_1657126_13 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 292.0
PYH3_k127_1657126_14 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001165 276.0
PYH3_k127_1657126_15 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001125 273.0
PYH3_k127_1657126_16 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 253.0
PYH3_k127_1657126_17 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000000000000000000005647 234.0
PYH3_k127_1657126_18 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000006066 213.0
PYH3_k127_1657126_19 Domain of unknown function (DUF4347) - - - 0.00000000000000000000000000000000000000000000162 175.0
PYH3_k127_1657126_2 membrane-associated Zn-dependent proteases 1 - - - 1.134e-226 722.0
PYH3_k127_1657126_20 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000002251 168.0
PYH3_k127_1657126_21 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000009683 153.0
PYH3_k127_1657126_22 - - - - 0.00000000000000000000000000000005663 132.0
PYH3_k127_1657126_23 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000001001 124.0
PYH3_k127_1657126_24 Protein of unknown function (DUF504) - - - 0.000000000000000000000000003705 114.0
PYH3_k127_1657126_25 - - - - 0.000000000000000000002403 96.0
PYH3_k127_1657126_26 GYD domain - - - 0.00000000000000000004888 95.0
PYH3_k127_1657126_27 Protein required for attachment to host cells - - - 0.0000000000000000000669 95.0
PYH3_k127_1657126_28 Belongs to the ParB family K03497 - - 0.0000000000003896 73.0
PYH3_k127_1657126_3 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 595.0
PYH3_k127_1657126_30 With YejAEF is involved in resistance to microcin C K02031,K02032 - - 0.00000002262 55.0
PYH3_k127_1657126_31 - - - - 0.000005742 55.0
PYH3_k127_1657126_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 592.0
PYH3_k127_1657126_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 568.0
PYH3_k127_1657126_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 432.0
PYH3_k127_1657126_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
PYH3_k127_1657126_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 376.0
PYH3_k127_1657126_9 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 361.0
PYH3_k127_1670655_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 3.9e-301 933.0
PYH3_k127_1670655_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.868e-242 751.0
PYH3_k127_1670655_10 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000008787 109.0
PYH3_k127_1670655_2 SAF - - - 8.482e-210 661.0
PYH3_k127_1670655_3 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 509.0
PYH3_k127_1670655_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 487.0
PYH3_k127_1670655_5 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 389.0
PYH3_k127_1670655_6 transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 352.0
PYH3_k127_1670655_7 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 342.0
PYH3_k127_1670655_8 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000001659 212.0
PYH3_k127_1670655_9 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000006137 154.0
PYH3_k127_1671029_0 carbohydrate binding - - - 0.0 3864.0
PYH3_k127_1671029_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 616.0
PYH3_k127_1671029_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 334.0
PYH3_k127_1671029_3 DnaJ C terminal domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002485 269.0
PYH3_k127_1671029_4 Ferritin, Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 265.0
PYH3_k127_1671029_5 BON domain K04065 - - 0.000000000000000000000000000000002754 133.0
PYH3_k127_1671029_6 - - - - 0.0000000000000000001478 94.0
PYH3_k127_1671029_7 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000001044 85.0
PYH3_k127_1671029_8 AI-2E family transporter - - - 0.0000006716 54.0
PYH3_k127_1671053_0 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 454.0
PYH3_k127_1671053_1 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001943 268.0
PYH3_k127_1672091_0 signal peptide protein K21006 - - 1.602e-262 838.0
PYH3_k127_1672091_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
PYH3_k127_1672091_10 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000000000004277 101.0
PYH3_k127_1672091_11 Bacterial Ig-like domain 2 - - - 0.00000005595 66.0
PYH3_k127_1672091_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 398.0
PYH3_k127_1672091_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 348.0
PYH3_k127_1672091_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 320.0
PYH3_k127_1672091_5 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 272.0
PYH3_k127_1672091_6 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000792 246.0
PYH3_k127_1672091_7 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000000000006401 169.0
PYH3_k127_1672091_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000003102 143.0
PYH3_k127_1672091_9 Tetratricopeptide repeat K21007 - - 0.0000000000000000000000000000000000008356 154.0
PYH3_k127_1681118_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.662e-221 697.0
PYH3_k127_1681118_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 578.0
PYH3_k127_1681118_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
PYH3_k127_1681118_11 binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 370.0
PYH3_k127_1681118_12 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 299.0
PYH3_k127_1681118_13 Catalyzes phosphorylation of fructose K00845,K00847 GO:0003674,GO:0003824,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.2,2.7.1.4 0.000000000001779 67.0
PYH3_k127_1681118_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 585.0
PYH3_k127_1681118_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 565.0
PYH3_k127_1681118_4 PFAM extracellular solute-binding protein family 1 K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 529.0
PYH3_k127_1681118_5 N-acyl-D-aspartate D-glutamate deacylase K06015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 537.0
PYH3_k127_1681118_6 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 538.0
PYH3_k127_1681118_7 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 457.0
PYH3_k127_1681118_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 436.0
PYH3_k127_1681118_9 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 398.0
PYH3_k127_169115_0 Transposase DDE domain - - - 3.825e-263 820.0
PYH3_k127_169115_1 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 525.0
PYH3_k127_169115_10 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.0000214 53.0
PYH3_k127_169115_11 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00002197 50.0
PYH3_k127_169115_12 - - - - 0.0005497 51.0
PYH3_k127_169115_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 418.0
PYH3_k127_169115_3 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
PYH3_k127_169115_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 404.0
PYH3_k127_169115_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000008538 240.0
PYH3_k127_169115_6 Transposase IS3 IS911 family protein K07497 - - 0.00000000000000000000000000000000000000002596 153.0
PYH3_k127_169115_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000001224 153.0
PYH3_k127_169115_8 Integrase catalytic region K07497 - - 0.000000000000000000000000007666 113.0
PYH3_k127_169115_9 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000003683 93.0
PYH3_k127_1702696_0 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 362.0
PYH3_k127_1725339_0 type VI secretion protein K11891 - - 0.0 1185.0
PYH3_k127_1725339_1 type VI secretion protein K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 475.0
PYH3_k127_1725339_2 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 454.0
PYH3_k127_1725339_3 TIGRFAM type VI secretion system FHA domain protein K07169,K11913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 327.0
PYH3_k127_1725339_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001317 262.0
PYH3_k127_1725339_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 258.0
PYH3_k127_1725339_6 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000001555 167.0
PYH3_k127_1725339_7 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.000000000000000000000000000004484 129.0
PYH3_k127_1753525_0 Iron-sulfur cluster binding protein K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 329.0
PYH3_k127_1753525_1 Transposase for IS481 element - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 321.0
PYH3_k127_1753525_2 Universal stress protein family - - - 0.0001393 52.0
PYH3_k127_176117_0 Proton-conducting membrane transporter - - - 7.6e-308 955.0
PYH3_k127_176117_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.218e-301 947.0
PYH3_k127_176117_10 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000732 276.0
PYH3_k127_176117_11 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000177 288.0
PYH3_k127_176117_12 SmpA / OmlA family - - - 0.00000000000000000000000000000005596 131.0
PYH3_k127_176117_13 copG family - - - 0.0000000000000000000005622 100.0
PYH3_k127_176117_14 aspartyl asparaginyl K12979 - - 0.000000000533 64.0
PYH3_k127_176117_15 Tetratricopeptide repeat K21010 - - 0.0000001454 55.0
PYH3_k127_176117_16 KR domain K00019 - 1.1.1.30 0.0001444 49.0
PYH3_k127_176117_2 Proton-conducting membrane transporter K12141 - - 6.078e-248 772.0
PYH3_k127_176117_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 5.101e-209 661.0
PYH3_k127_176117_4 glycosyl transferase K21011 - - 1.128e-197 630.0
PYH3_k127_176117_5 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 567.0
PYH3_k127_176117_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 552.0
PYH3_k127_176117_7 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 496.0
PYH3_k127_176117_8 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 474.0
PYH3_k127_176117_9 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 316.0
PYH3_k127_17680_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 284.0
PYH3_k127_17680_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000003471 247.0
PYH3_k127_17680_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000000003163 157.0
PYH3_k127_17680_3 PFAM PIN domain - - - 0.0000000000000000000000001193 111.0
PYH3_k127_17680_4 ORF6N domain - - - 0.0000000000000000000003796 104.0
PYH3_k127_17680_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000004651 57.0
PYH3_k127_1779641_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 2.773e-212 677.0
PYH3_k127_1779641_1 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 602.0
PYH3_k127_1779641_10 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000002126 88.0
PYH3_k127_1779641_2 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 591.0
PYH3_k127_1779641_3 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 325.0
PYH3_k127_1779641_4 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
PYH3_k127_1779641_5 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006272 251.0
PYH3_k127_1779641_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 258.0
PYH3_k127_1779641_7 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001538 231.0
PYH3_k127_1779641_8 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000002383 198.0
PYH3_k127_1779641_9 - - - - 0.000000000000000000000000003175 115.0
PYH3_k127_1799563_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 597.0
PYH3_k127_1799563_1 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 480.0
PYH3_k127_1799563_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 479.0
PYH3_k127_1799563_3 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000001633 184.0
PYH3_k127_1799563_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000004754 62.0
PYH3_k127_1799563_5 cytochrome complex assembly - - - 0.00001449 54.0
PYH3_k127_1804410_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.205e-309 968.0
PYH3_k127_1804410_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.898e-273 844.0
PYH3_k127_1804410_10 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.00000000000000002447 89.0
PYH3_k127_1804410_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 555.0
PYH3_k127_1804410_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 362.0
PYH3_k127_1804410_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002859 260.0
PYH3_k127_1804410_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000007452 220.0
PYH3_k127_1804410_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000003724 183.0
PYH3_k127_1804410_7 transcriptional - - - 0.00000000000000000000000000000000000000000000003781 172.0
PYH3_k127_1804410_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000001979 166.0
PYH3_k127_1804410_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000102 108.0
PYH3_k127_1808443_0 Neisseria PilC beta-propeller domain K02674 - - 2.139e-239 780.0
PYH3_k127_1808443_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 372.0
PYH3_k127_1808443_2 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000000004353 250.0
PYH3_k127_1808443_3 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000001494 191.0
PYH3_k127_1808443_4 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000002508 153.0
PYH3_k127_1808443_5 Type II transport protein GspH K08084 - - 0.000000000000000000000000000000000001301 147.0
PYH3_k127_1808443_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000000001836 135.0
PYH3_k127_1808443_7 type IV pilus modification protein PilV K02671 - - 0.0000000000000000002769 93.0
PYH3_k127_1808443_8 import inner membrane translocase, subunit Tim44 - - - 0.0001037 48.0
PYH3_k127_1816957_0 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 450.0
PYH3_k127_1816957_1 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 389.0
PYH3_k127_1816957_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 373.0
PYH3_k127_1816957_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001334 136.0
PYH3_k127_1816957_4 PFAM glutaredoxin - - - 0.000000000000000000001979 99.0
PYH3_k127_186369_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007383 264.0
PYH3_k127_186369_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000001149 230.0
PYH3_k127_186369_2 transcriptional regulator K07734 - - 0.0000000000000000000000000000007996 124.0
PYH3_k127_1873611_0 Uncharacterized protein family (UPF0051) K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000008322 233.0
PYH3_k127_1873611_1 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001557 221.0
PYH3_k127_1873611_2 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000004727 173.0
PYH3_k127_1873611_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000153 131.0
PYH3_k127_1894517_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 8.43e-212 672.0
PYH3_k127_1894517_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 609.0
PYH3_k127_1894517_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 560.0
PYH3_k127_1894517_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 379.0
PYH3_k127_1894517_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 366.0
PYH3_k127_1894517_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
PYH3_k127_1894517_6 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000002807 204.0
PYH3_k127_1894517_7 ferredoxin - - - 0.00000000000000000000000000000442 119.0
PYH3_k127_191375_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 434.0
PYH3_k127_191375_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.000000000000000000000000000000000000000000000000009033 180.0
PYH3_k127_191375_2 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.0000000000000000000000000000000000000000006797 163.0
PYH3_k127_1915249_0 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 300.0
PYH3_k127_1915249_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000007573 237.0
PYH3_k127_1915249_2 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000000000000003737 194.0
PYH3_k127_1915249_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000002972 99.0
PYH3_k127_1915249_4 PEP-CTERM motif - - - 0.0000000000000001292 88.0
PYH3_k127_1950501_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 3.936e-267 853.0
PYH3_k127_1950501_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.299e-264 825.0
PYH3_k127_1950501_2 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 7.728e-218 684.0
PYH3_k127_1950501_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 472.0
PYH3_k127_1950501_4 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 380.0
PYH3_k127_1950501_5 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
PYH3_k127_1950501_6 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 370.0
PYH3_k127_1950501_7 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 334.0
PYH3_k127_1950501_8 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000001728 147.0
PYH3_k127_1962046_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 387.0
PYH3_k127_1962046_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 371.0
PYH3_k127_1962046_2 Bacterial regulatory proteins, lacI family K02529 - - 0.0000000000000002306 82.0
PYH3_k127_1975617_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 7.739e-224 707.0
PYH3_k127_1975617_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 332.0
PYH3_k127_2003643_0 CoA-transferase family III K07749 - 2.8.3.16 3.202e-201 635.0
PYH3_k127_2003643_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 579.0
PYH3_k127_2003643_10 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000002275 199.0
PYH3_k127_2003643_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000011 181.0
PYH3_k127_2003643_12 membrane - - - 0.0000000000000000000000000000000000035 141.0
PYH3_k127_2003643_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000933 133.0
PYH3_k127_2003643_14 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000001762 121.0
PYH3_k127_2003643_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 503.0
PYH3_k127_2003643_3 NMT1-like family K02051,K15576,K22067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 498.0
PYH3_k127_2003643_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 492.0
PYH3_k127_2003643_5 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 446.0
PYH3_k127_2003643_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 367.0
PYH3_k127_2003643_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001684 267.0
PYH3_k127_2003643_8 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000002248 215.0
PYH3_k127_2003643_9 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000003094 213.0
PYH3_k127_2028642_0 Protein of unknown function - - - 8.937e-278 902.0
PYH3_k127_2028642_1 peptidase U62, modulator of DNA gyrase K03568 - - 2.245e-217 685.0
PYH3_k127_2028642_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 362.0
PYH3_k127_209425_0 glycosyl transferase family 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 346.0
PYH3_k127_209425_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000008394 223.0
PYH3_k127_215785_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 588.0
PYH3_k127_215785_1 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 524.0
PYH3_k127_215785_10 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000069 103.0
PYH3_k127_215785_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 476.0
PYH3_k127_215785_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 464.0
PYH3_k127_215785_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH3_k127_215785_5 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000002247 244.0
PYH3_k127_215785_6 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000002576 226.0
PYH3_k127_215785_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000004238 182.0
PYH3_k127_215785_8 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000005244 141.0
PYH3_k127_215785_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000004554 125.0
PYH3_k127_216264_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 1.772e-260 809.0
PYH3_k127_216264_1 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 582.0
PYH3_k127_216264_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 542.0
PYH3_k127_216264_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 498.0
PYH3_k127_216264_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 473.0
PYH3_k127_216264_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 386.0
PYH3_k127_216264_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000002508 238.0
PYH3_k127_216264_7 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000005572 153.0
PYH3_k127_216264_8 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000009992 105.0
PYH3_k127_2279930_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009315 259.0
PYH3_k127_2307106_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.607e-212 679.0
PYH3_k127_2307106_1 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K17204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 589.0
PYH3_k127_2307106_10 - - - - 0.00000000000000000000000000000000002687 137.0
PYH3_k127_2307106_11 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000008863 126.0
PYH3_k127_2307106_12 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000001262 112.0
PYH3_k127_2307106_13 membrane - - - 0.00000008862 59.0
PYH3_k127_2307106_14 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00003664 51.0
PYH3_k127_2307106_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 533.0
PYH3_k127_2307106_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 498.0
PYH3_k127_2307106_4 ABC-type sugar transport system periplasmic component K10439,K17202,K17205,K17213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 406.0
PYH3_k127_2307106_5 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 391.0
PYH3_k127_2307106_6 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 322.0
PYH3_k127_2307106_7 2-Keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 307.0
PYH3_k127_2307106_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000003754 189.0
PYH3_k127_2307106_9 RbsD / FucU transport protein family - - - 0.000000000000000000000000000000000000000004447 158.0
PYH3_k127_2308986_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 374.0
PYH3_k127_2308986_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000005682 48.0
PYH3_k127_230969_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 4.839e-197 630.0
PYH3_k127_230969_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007062 252.0
PYH3_k127_230969_2 Belongs to the 'phage' integrase family - - - 0.0001668 44.0
PYH3_k127_2318049_0 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 414.0
PYH3_k127_2318049_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 397.0
PYH3_k127_2318049_10 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000001137 210.0
PYH3_k127_2318049_11 - - - - 0.000000000000000000000000000000000000000000000000000002 198.0
PYH3_k127_2318049_12 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000003142 176.0
PYH3_k127_2318049_2 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 334.0
PYH3_k127_2318049_3 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 329.0
PYH3_k127_2318049_4 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 323.0
PYH3_k127_2318049_5 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 324.0
PYH3_k127_2318049_6 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
PYH3_k127_2318049_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007599 272.0
PYH3_k127_2318049_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005542 261.0
PYH3_k127_2318049_9 Domain of unknown function (DUF4384) - - - 0.000000000000000000000000000000000000000000000000000000000000000005757 246.0
PYH3_k127_2330066_0 D-amino acid K00285 - 1.4.5.1 9.238e-211 660.0
PYH3_k127_2330066_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 486.0
PYH3_k127_2330066_2 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 484.0
PYH3_k127_2330066_3 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 442.0
PYH3_k127_2330066_4 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 308.0
PYH3_k127_2330066_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000005374 263.0
PYH3_k127_2330066_6 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000001063 198.0
PYH3_k127_2330066_7 COG0112 Glycine serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000003007 167.0
PYH3_k127_2330066_8 Type II transport protein GspH K08084 - - 0.000000000000001059 87.0
PYH3_k127_2330066_9 - - - - 0.0000000000001153 83.0
PYH3_k127_2349377_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000003221 162.0
PYH3_k127_2349377_1 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000000002484 111.0
PYH3_k127_2349377_2 Protein of unknown function DUF86 - - - 0.00000000000000000000002009 104.0
PYH3_k127_2349377_3 Type I site-specific restriction-modification system, R (Restriction) subunit and related K01153 - 3.1.21.3 0.0000002405 54.0
PYH3_k127_2397953_0 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.092e-201 636.0
PYH3_k127_2397953_1 CoA-transferase family III K07749 - 2.8.3.16 3.493e-198 623.0
PYH3_k127_2397953_10 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001569 255.0
PYH3_k127_2397953_11 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000005044 246.0
PYH3_k127_2397953_12 lipase activity - - - 0.0000000000000000000000000000000000000000000000000001053 199.0
PYH3_k127_2397953_13 PQ loop repeat K15383 - - 0.000000000000000000000000005366 115.0
PYH3_k127_2397953_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 542.0
PYH3_k127_2397953_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 457.0
PYH3_k127_2397953_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 411.0
PYH3_k127_2397953_5 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 401.0
PYH3_k127_2397953_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 340.0
PYH3_k127_2397953_7 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
PYH3_k127_2397953_8 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008698 269.0
PYH3_k127_2397953_9 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
PYH3_k127_2426132_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 1.667e-282 876.0
PYH3_k127_2426132_1 formate dehydrogenase K00123 - 1.17.1.9 2.029e-261 810.0
PYH3_k127_2426132_10 alginic acid biosynthetic process K12287 - - 0.0000000000000000000000000000000000000000000000002156 203.0
PYH3_k127_2426132_11 Prokaryotic N-terminal methylation motif K12285 - - 0.000000000000000000000000000000000000000000000002153 183.0
PYH3_k127_2426132_12 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000007583 156.0
PYH3_k127_2426132_13 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000001014 126.0
PYH3_k127_2426132_14 Prokaryotic N-terminal methylation motif K10924 - - 0.0000000000000000000000000001333 120.0
PYH3_k127_2426132_15 Pilus assembly protein PilX K12286 - - 0.0000000000000000000000001792 114.0
PYH3_k127_2426132_16 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.00000000000000000000006988 100.0
PYH3_k127_2426132_17 Pilus assembly protein K12279 - - 0.0000000000000000001322 100.0
PYH3_k127_2426132_18 Tfp pilus assembly protein FimT K10926 - - 0.0000000000000003079 87.0
PYH3_k127_2426132_19 PFAM Fimbrial assembly family protein - - - 0.0000000000001311 79.0
PYH3_k127_2426132_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.082e-237 754.0
PYH3_k127_2426132_20 carbon utilization K12280 - - 0.0000000000004739 79.0
PYH3_k127_2426132_22 Tetratricopeptide repeat K12284 - - 0.0000253 57.0
PYH3_k127_2426132_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 584.0
PYH3_k127_2426132_4 type II and III secretion system protein K02453,K12282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 503.0
PYH3_k127_2426132_5 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 460.0
PYH3_k127_2426132_6 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 375.0
PYH3_k127_2426132_7 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 317.0
PYH3_k127_2426132_8 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 322.0
PYH3_k127_2426132_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002561 282.0
PYH3_k127_244189_0 - - - - 0.00000000000000000000000000000000000000000000000007815 196.0
PYH3_k127_244189_1 SurA N-terminal domain - - - 0.00000000000000000000000000000006841 128.0
PYH3_k127_2447766_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1439.0
PYH3_k127_2447766_1 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 4.441e-248 771.0
PYH3_k127_2447766_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 599.0
PYH3_k127_2447766_3 Na Pi-cotransporter II-related protein K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 595.0
PYH3_k127_2447766_4 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 492.0
PYH3_k127_2447766_5 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
PYH3_k127_2447766_6 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002315 282.0
PYH3_k127_2447766_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000004491 202.0
PYH3_k127_2447766_8 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00003922 47.0
PYH3_k127_2468414_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 5.717e-271 847.0
PYH3_k127_2468414_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 1.349e-223 708.0
PYH3_k127_2468414_10 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 276.0
PYH3_k127_2468414_11 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000001297 186.0
PYH3_k127_2468414_12 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000006989 188.0
PYH3_k127_2468414_13 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000002928 178.0
PYH3_k127_2468414_14 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000002142 181.0
PYH3_k127_2468414_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000000006205 148.0
PYH3_k127_2468414_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001768 147.0
PYH3_k127_2468414_17 ASCH - - - 0.0000000000000000000000000000003538 128.0
PYH3_k127_2468414_19 DnaJ domain protein - - - 0.0000009869 57.0
PYH3_k127_2468414_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 2.136e-223 707.0
PYH3_k127_2468414_3 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 8.08e-217 677.0
PYH3_k127_2468414_4 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 493.0
PYH3_k127_2468414_5 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 436.0
PYH3_k127_2468414_6 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 409.0
PYH3_k127_2468414_7 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 400.0
PYH3_k127_2468414_8 threonine dehydratase K17989 GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 372.0
PYH3_k127_2468414_9 Protein conserved in bacteria K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 342.0
PYH3_k127_2480157_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.718e-308 959.0
PYH3_k127_2480157_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.281e-296 917.0
PYH3_k127_2480157_10 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 355.0
PYH3_k127_2480157_11 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 304.0
PYH3_k127_2480157_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 262.0
PYH3_k127_2480157_13 Cytochrome K08738 - - 0.0000000000000000000000000000000001504 135.0
PYH3_k127_2480157_14 Universal stress protein - - - 0.00000000000000000000906 93.0
PYH3_k127_2480157_15 - - - - 0.00000004452 57.0
PYH3_k127_2480157_2 AMP-binding enzyme C-terminal domain K18661 - - 1.906e-224 707.0
PYH3_k127_2480157_3 PFAM major facilitator superfamily MFS_1 K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 601.0
PYH3_k127_2480157_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 475.0
PYH3_k127_2480157_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 464.0
PYH3_k127_2480157_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 457.0
PYH3_k127_2480157_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 441.0
PYH3_k127_2480157_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 396.0
PYH3_k127_2480157_9 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 393.0
PYH3_k127_2517014_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 421.0
PYH3_k127_2517014_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 366.0
PYH3_k127_2517014_2 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000005213 166.0
PYH3_k127_2517014_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000006579 147.0
PYH3_k127_2523768_0 Zinc-binding domain of primase-helicase K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
PYH3_k127_2523768_1 - - - - 0.000000000000000000000000000001873 124.0
PYH3_k127_2523768_2 Domain of unknown function (DUF1845) - - - 0.0000008636 54.0
PYH3_k127_2523768_3 - - - - 0.000006086 52.0
PYH3_k127_2548898_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 503.0
PYH3_k127_2548898_1 Protein of unknown function (DUF499) K06922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 339.0
PYH3_k127_2548898_2 transcriptional regulator K07726 - - 0.00000000000000000000000002955 112.0
PYH3_k127_2548898_3 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000003392 104.0
PYH3_k127_2548898_4 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000001942 72.0
PYH3_k127_2548898_5 ADP binding - - - 0.0009318 47.0
PYH3_k127_2553328_0 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 509.0
PYH3_k127_2553328_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 420.0
PYH3_k127_2553328_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 402.0
PYH3_k127_2586351_0 impB/mucB/samB family K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001908 287.0
PYH3_k127_2586351_1 Damage-inducible protein DinB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006756 259.0
PYH3_k127_2586351_2 ORF6N domain - - - 0.000000000000000000000000000000000000000000005641 167.0
PYH3_k127_2586351_3 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000000000000000000001222 96.0
PYH3_k127_2586351_4 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.0000000000000005364 80.0
PYH3_k127_2586351_5 Protein of unknown function (DUF2442) - - - 0.0000000000000159 77.0
PYH3_k127_2615247_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 8.106e-270 834.0
PYH3_k127_2615247_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 586.0
PYH3_k127_2615247_10 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000000005283 78.0
PYH3_k127_2615247_11 Cytochrome oxidase maturation protein - - - 0.00000003725 57.0
PYH3_k127_2615247_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 587.0
PYH3_k127_2615247_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 382.0
PYH3_k127_2615247_4 Bacterial regulatory proteins, crp family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 353.0
PYH3_k127_2615247_5 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 331.0
PYH3_k127_2615247_6 cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000004269 204.0
PYH3_k127_2615247_7 FixH family K09926 - - 0.000000000000000000000000000000607 128.0
PYH3_k127_2615247_8 - - - - 0.000000000000000000000000003104 114.0
PYH3_k127_2615247_9 biogenesis protein K09792 - - 0.0000000000000001676 85.0
PYH3_k127_2628408_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 515.0
PYH3_k127_2628408_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 417.0
PYH3_k127_2628408_2 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.000000000000000000000000000000000000000000000000007714 192.0
PYH3_k127_264588_0 AMP-binding enzyme C-terminal domain - - - 1.243e-235 738.0
PYH3_k127_264588_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 450.0
PYH3_k127_264588_10 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000002631 195.0
PYH3_k127_264588_11 Biopolymer transport K03559 - - 0.000000000000000000000000000000000009332 150.0
PYH3_k127_264588_12 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000005942 130.0
PYH3_k127_264588_13 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000002377 97.0
PYH3_k127_264588_14 Universal stress protein - - - 0.000000000000711 72.0
PYH3_k127_264588_2 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 400.0
PYH3_k127_264588_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 331.0
PYH3_k127_264588_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 331.0
PYH3_k127_264588_5 Biopolymer transport K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000537 274.0
PYH3_k127_264588_6 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001246 265.0
PYH3_k127_264588_7 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001918 268.0
PYH3_k127_264588_8 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007941 226.0
PYH3_k127_264588_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000006428 200.0
PYH3_k127_2673617_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 522.0
PYH3_k127_2673617_1 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004438 273.0
PYH3_k127_2673695_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1047.0
PYH3_k127_2673695_1 Highly conserved protein containing a thioredoxin domain K06888 - - 9.021e-236 751.0
PYH3_k127_2673695_10 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000218 132.0
PYH3_k127_2673695_11 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000001564 130.0
PYH3_k127_2673695_12 PFAM SpoVT AbrB - - - 0.00000000000000000000000000001788 119.0
PYH3_k127_2673695_13 - - - - 0.00000000000000000000007774 99.0
PYH3_k127_2673695_2 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 467.0
PYH3_k127_2673695_3 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 417.0
PYH3_k127_2673695_4 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 315.0
PYH3_k127_2673695_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
PYH3_k127_2673695_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
PYH3_k127_2673695_7 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008209 231.0
PYH3_k127_2673695_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000005458 225.0
PYH3_k127_2673695_9 COGs COG1569 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000000000000000000009426 183.0
PYH3_k127_2676463_0 ABC-type Fe3 transport system permease component K02011 - - 6.004e-254 795.0
PYH3_k127_2676463_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 3.482e-203 637.0
PYH3_k127_2676463_10 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000005611 88.0
PYH3_k127_2676463_2 ABC-type Fe3 transport system, periplasmic component - - - 8.571e-196 621.0
PYH3_k127_2676463_3 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 483.0
PYH3_k127_2676463_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 459.0
PYH3_k127_2676463_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 402.0
PYH3_k127_2676463_6 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 320.0
PYH3_k127_2676463_7 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
PYH3_k127_2676463_8 PFAM acyl-coA-binding protein, ACBP - - - 0.0000000000000000000000000000000008315 132.0
PYH3_k127_2676463_9 CHRD domain - - - 0.0000000000000000000000000001326 123.0
PYH3_k127_2708096_0 Histidine kinase K02487,K06596 - - 0.0 1250.0
PYH3_k127_2708096_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.041e-289 894.0
PYH3_k127_2708096_10 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 394.0
PYH3_k127_2708096_11 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 371.0
PYH3_k127_2708096_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 336.0
PYH3_k127_2708096_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 314.0
PYH3_k127_2708096_14 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 301.0
PYH3_k127_2708096_15 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003813 275.0
PYH3_k127_2708096_16 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
PYH3_k127_2708096_17 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 260.0
PYH3_k127_2708096_18 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000002043 247.0
PYH3_k127_2708096_19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
PYH3_k127_2708096_2 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 3.339e-209 658.0
PYH3_k127_2708096_20 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000006138 231.0
PYH3_k127_2708096_21 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000003698 213.0
PYH3_k127_2708096_22 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000006433 211.0
PYH3_k127_2708096_23 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000363 197.0
PYH3_k127_2708096_24 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000001034 186.0
PYH3_k127_2708096_25 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000007251 177.0
PYH3_k127_2708096_26 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000804 173.0
PYH3_k127_2708096_27 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000002433 175.0
PYH3_k127_2708096_28 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000003278 166.0
PYH3_k127_2708096_29 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000007548 152.0
PYH3_k127_2708096_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 1.461e-201 640.0
PYH3_k127_2708096_30 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000001661 143.0
PYH3_k127_2708096_31 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000003503 123.0
PYH3_k127_2708096_32 CheW-like domain K02659 - - 0.000000000000000000000000000006916 125.0
PYH3_k127_2708096_33 CRISPR_assoc - - - 0.00000778 57.0
PYH3_k127_2708096_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 570.0
PYH3_k127_2708096_5 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 539.0
PYH3_k127_2708096_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 516.0
PYH3_k127_2708096_7 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 524.0
PYH3_k127_2708096_8 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 497.0
PYH3_k127_2708096_9 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 462.0
PYH3_k127_2710583_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 5.274e-285 899.0
PYH3_k127_2710583_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.638e-201 637.0
PYH3_k127_2710583_10 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008577 247.0
PYH3_k127_2710583_11 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000009456 245.0
PYH3_k127_2710583_12 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000002093 235.0
PYH3_k127_2710583_13 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000005067 216.0
PYH3_k127_2710583_14 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000001057 145.0
PYH3_k127_2710583_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001081 139.0
PYH3_k127_2710583_16 peptidyl-prolyl K03775 - 5.2.1.8 0.0000000000000000000000000000000104 134.0
PYH3_k127_2710583_17 - - - - 0.000000009025 66.0
PYH3_k127_2710583_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 556.0
PYH3_k127_2710583_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 400.0
PYH3_k127_2710583_4 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 384.0
PYH3_k127_2710583_5 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 380.0
PYH3_k127_2710583_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 372.0
PYH3_k127_2710583_7 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 330.0
PYH3_k127_2710583_8 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001286 278.0
PYH3_k127_2710583_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
PYH3_k127_2722135_0 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 580.0
PYH3_k127_2722135_1 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 396.0
PYH3_k127_2722135_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 284.0
PYH3_k127_2722135_3 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
PYH3_k127_2722135_4 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000009038 225.0
PYH3_k127_2722135_5 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000002685 157.0
PYH3_k127_2722135_6 Methyltransferase K08316 - 2.1.1.171 0.0000000000000003441 82.0
PYH3_k127_2746141_0 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
PYH3_k127_2746141_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000002084 148.0
PYH3_k127_2746141_2 - - - - 0.00000000000000000007996 94.0
PYH3_k127_2747558_0 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 362.0
PYH3_k127_2747558_1 PFAM RNA-directed DNA polymerase (reverse transcriptase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 331.0
PYH3_k127_2747558_2 CoA-binding domain protein K09181 - - 0.000000000000000000000000000003153 136.0
PYH3_k127_2747558_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000003634 112.0
PYH3_k127_2787000_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 499.0
PYH3_k127_2787000_1 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 301.0
PYH3_k127_2787000_2 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
PYH3_k127_2787000_3 acyl-CoA dehydrogenase - - - 0.000000011 65.0
PYH3_k127_2787002_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 488.0
PYH3_k127_2787002_1 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 300.0
PYH3_k127_2787002_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000007126 210.0
PYH3_k127_2787002_3 acyl-CoA dehydrogenase - - - 0.000000000000000071 93.0
PYH3_k127_2827674_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 3.072e-264 830.0
PYH3_k127_2827674_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 4.009e-242 762.0
PYH3_k127_2827674_2 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 396.0
PYH3_k127_2827674_3 viral genome integration into host DNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 413.0
PYH3_k127_2827674_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 336.0
PYH3_k127_2827674_5 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000002344 225.0
PYH3_k127_2827674_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000002534 141.0
PYH3_k127_2827674_7 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000002717 131.0
PYH3_k127_2827674_8 Alpha beta hydrolase - - - 0.0003961 46.0
PYH3_k127_2832597_0 GTP-binding protein K06207 - - 0.0 1006.0
PYH3_k127_2832597_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
PYH3_k127_2832597_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006718 289.0
PYH3_k127_2832597_3 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001348 260.0
PYH3_k127_2839662_0 Transposase K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
PYH3_k127_2839662_1 IS66 Orf2 like protein - - - 0.00000000000000000000000000000000000000000000000000000001322 207.0
PYH3_k127_2839662_2 Transposase K07483 - - 0.0000000000000000001092 94.0
PYH3_k127_2839662_3 - - - - 0.000000000000000141 83.0
PYH3_k127_2843887_0 Dehydratase family K13875 - 4.2.1.25 9.82e-302 932.0
PYH3_k127_2843887_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 511.0
PYH3_k127_2843887_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 509.0
PYH3_k127_2843887_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 441.0
PYH3_k127_2843887_4 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 436.0
PYH3_k127_2843887_5 PFAM NAD-dependent epimerase dehydratase K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
PYH3_k127_2843887_6 transcription regulator containing HTH domain - - - 0.00000000000000000000000000000000000000000000000002629 181.0
PYH3_k127_2843887_7 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.000000000000000000000000000000000000000000002966 166.0
PYH3_k127_2843887_8 Endonuclease/Exonuclease/phosphatase family - - - 0.000186 48.0
PYH3_k127_2846762_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.514e-311 965.0
PYH3_k127_2846762_1 heat shock protein binding - - - 2.719e-260 823.0
PYH3_k127_2846762_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000184 240.0
PYH3_k127_2846762_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000001449 235.0
PYH3_k127_2846762_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000007039 205.0
PYH3_k127_2846762_13 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000005017 155.0
PYH3_k127_2846762_14 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000001055 57.0
PYH3_k127_2846762_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 5.037e-209 662.0
PYH3_k127_2846762_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 5.637e-203 654.0
PYH3_k127_2846762_4 Decaheme c-type cytochrome, DmsE family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 394.0
PYH3_k127_2846762_5 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 385.0
PYH3_k127_2846762_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
PYH3_k127_2846762_7 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 305.0
PYH3_k127_2846762_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
PYH3_k127_2846762_9 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005495 244.0
PYH3_k127_2872908_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 1.087e-228 713.0
PYH3_k127_2872908_1 Domain of unknown function (DUF3390) K18929 - - 1.633e-203 651.0
PYH3_k127_2872908_10 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003268 277.0
PYH3_k127_2872908_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000004615 264.0
PYH3_k127_2872908_12 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
PYH3_k127_2872908_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000009547 198.0
PYH3_k127_2872908_14 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000408 203.0
PYH3_k127_2872908_15 - - - - 0.00000000000000000000000000000000000000000001851 166.0
PYH3_k127_2872908_16 Cyclase dehydrase - - - 0.00000000000000000000000000000000000002232 156.0
PYH3_k127_2872908_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000002722 104.0
PYH3_k127_2872908_18 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000005323 51.0
PYH3_k127_2872908_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 583.0
PYH3_k127_2872908_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 493.0
PYH3_k127_2872908_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 479.0
PYH3_k127_2872908_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 460.0
PYH3_k127_2872908_6 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 377.0
PYH3_k127_2872908_7 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 347.0
PYH3_k127_2872908_8 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001892 282.0
PYH3_k127_2872908_9 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
PYH3_k127_2889055_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000004435 127.0
PYH3_k127_2889055_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position - - - 0.0000000000000000000000000000558 131.0
PYH3_k127_2889055_2 PFAM OmpA MotB domain protein - - - 0.000000000001244 76.0
PYH3_k127_2889055_3 alpha amylase, catalytic region - - - 0.00000000001376 66.0
PYH3_k127_2889055_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.00000000003419 66.0
PYH3_k127_2889055_5 Meiotic cell cortex C-terminal pleckstrin homology K17978 GO:0000001,GO:0000003,GO:0000226,GO:0000266,GO:0000280,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005856,GO:0005938,GO:0006810,GO:0006928,GO:0006996,GO:0007005,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007127,GO:0008092,GO:0008104,GO:0008150,GO:0009987,GO:0010970,GO:0015630,GO:0015631,GO:0016043,GO:0022402,GO:0022414,GO:0030473,GO:0030705,GO:0030863,GO:0030981,GO:0030989,GO:0032065,GO:0032507,GO:0033036,GO:0034613,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043495,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045185,GO:0046907,GO:0048285,GO:0048308,GO:0048311,GO:0051012,GO:0051179,GO:0051234,GO:0051235,GO:0051321,GO:0051640,GO:0051641,GO:0051646,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0061982,GO:0065007,GO:0065008,GO:0070727,GO:0071840,GO:0071944,GO:0072384,GO:0099111,GO:0099568,GO:0140013,GO:1903046 - 0.000006344 58.0
PYH3_k127_2894101_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 310.0
PYH3_k127_2894101_1 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001382 252.0
PYH3_k127_2894101_2 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.00000000000000000000000000000000000000000000000000000000000000000000105 238.0
PYH3_k127_2904270_0 - - - - 0.0 2008.0
PYH3_k127_2904270_1 - - - - 0.0 1743.0
PYH3_k127_2946156_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.19e-264 827.0
PYH3_k127_2946156_1 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 606.0
PYH3_k127_2946156_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 460.0
PYH3_k127_2946156_3 PFAM Serine threonine protein kinase-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 397.0
PYH3_k127_2946156_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005114 280.0
PYH3_k127_2946156_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000004423 251.0
PYH3_k127_2946156_6 LppC putative lipoprotein K07121 - - 0.000000002234 66.0
PYH3_k127_2964254_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1177.0
PYH3_k127_2964254_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1053.0
PYH3_k127_2964254_10 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004213 274.0
PYH3_k127_2964254_11 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000002307 198.0
PYH3_k127_2964254_12 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000001245 196.0
PYH3_k127_2964254_13 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000004708 166.0
PYH3_k127_2964254_14 transcriptional regulator - - - 0.0000000000000000000000000000000000000009025 155.0
PYH3_k127_2964254_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001295 156.0
PYH3_k127_2964254_16 acetyltransferase - - - 0.00000000000000000000000000000000001071 142.0
PYH3_k127_2964254_17 - - - - 0.0000000000000000000000000001775 121.0
PYH3_k127_2964254_18 Domain of unknown function (DUF4437) - - - 0.0000000000005931 76.0
PYH3_k127_2964254_19 Double zinc ribbon - - - 0.0004606 51.0
PYH3_k127_2964254_2 Alpha beta hydrolase K03821 - - 5.604e-207 661.0
PYH3_k127_2964254_3 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 567.0
PYH3_k127_2964254_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 558.0
PYH3_k127_2964254_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 536.0
PYH3_k127_2964254_6 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 447.0
PYH3_k127_2964254_7 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 371.0
PYH3_k127_2964254_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 373.0
PYH3_k127_2964254_9 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000032 268.0
PYH3_k127_2982278_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 3.323e-243 760.0
PYH3_k127_2982278_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 376.0
PYH3_k127_2982278_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
PYH3_k127_3003193_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.449e-250 782.0
PYH3_k127_3003193_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.4e-216 685.0
PYH3_k127_3003193_2 metal-dependent phosphoesterases (PHP family) K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
PYH3_k127_3003193_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 342.0
PYH3_k127_3003193_4 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 302.0
PYH3_k127_3003193_5 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 288.0
PYH3_k127_3003193_6 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
PYH3_k127_3003193_7 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000001638 170.0
PYH3_k127_3014273_0 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 518.0
PYH3_k127_3014273_1 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 486.0
PYH3_k127_3014273_2 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 479.0
PYH3_k127_3014273_3 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 429.0
PYH3_k127_3048965_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 481.0
PYH3_k127_3048965_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 393.0
PYH3_k127_3048965_2 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 313.0
PYH3_k127_3048965_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 303.0
PYH3_k127_3048965_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007853 287.0
PYH3_k127_3048965_5 DoxX-like family - - - 0.0000000000000000000000000000000000000000000000001937 180.0
PYH3_k127_3048965_6 Major Facilitator Superfamily - - - 0.0000000000004753 72.0
PYH3_k127_3048965_7 DNA integration K04763 - - 0.000001149 50.0
PYH3_k127_3166514_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.816e-265 839.0
PYH3_k127_3195307_0 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 341.0
PYH3_k127_3195307_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000006944 106.0
PYH3_k127_3195307_2 Phosphopantetheine attachment site - - - 0.00000000000000009694 92.0
PYH3_k127_3195794_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 8.512e-302 930.0
PYH3_k127_3195794_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 333.0
PYH3_k127_3215216_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 383.0
PYH3_k127_3215216_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001083 228.0
PYH3_k127_3215216_2 - - - - 0.000000000000000000000000000000000000000000000000000005799 195.0
PYH3_k127_3215216_3 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000001052 184.0
PYH3_k127_3215216_4 transcription regulator containing HTH domain K18831 - - 0.000000000000000000000000001586 117.0
PYH3_k127_3215216_5 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system - - - 0.000000000000000000000001154 106.0
PYH3_k127_3215216_6 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000542 81.0
PYH3_k127_3216213_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 352.0
PYH3_k127_3216213_1 Domain of unknown function (DUF4347) - - - 0.0000001213 62.0
PYH3_k127_32229_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1186.0
PYH3_k127_32229_1 Periplasmic binding protein K01999 - - 6.537e-205 649.0
PYH3_k127_32229_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
PYH3_k127_32229_11 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
PYH3_k127_32229_12 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007787 279.0
PYH3_k127_32229_13 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004648 253.0
PYH3_k127_32229_14 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002005 251.0
PYH3_k127_32229_15 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
PYH3_k127_32229_16 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000000000000000000000000381 199.0
PYH3_k127_32229_17 rhamnose metabolic process - - - 0.000000000000000000000000000000006869 129.0
PYH3_k127_32229_18 - - - - 0.000000000000000000000002086 113.0
PYH3_k127_32229_19 AcrB/AcrD/AcrF family K03296,K18138,K18902 - - 0.00000000000000000000007051 99.0
PYH3_k127_32229_2 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 539.0
PYH3_k127_32229_20 Protein of unknown function (DUF3303) - - - 0.00000000000000000000176 96.0
PYH3_k127_32229_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 510.0
PYH3_k127_32229_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 423.0
PYH3_k127_32229_5 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 423.0
PYH3_k127_32229_6 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 418.0
PYH3_k127_32229_7 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 417.0
PYH3_k127_32229_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 403.0
PYH3_k127_32229_9 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 367.0
PYH3_k127_3225512_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 1.438e-196 639.0
PYH3_k127_3225512_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 514.0
PYH3_k127_3225512_2 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 490.0
PYH3_k127_3225512_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 432.0
PYH3_k127_3225512_4 utilization protein B K13795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 423.0
PYH3_k127_3225512_5 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 343.0
PYH3_k127_3225512_6 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 343.0
PYH3_k127_3225512_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006254 241.0
PYH3_k127_3245973_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.375e-268 845.0
PYH3_k127_3245973_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.272e-238 743.0
PYH3_k127_3245973_10 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 513.0
PYH3_k127_3245973_11 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 502.0
PYH3_k127_3245973_12 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 457.0
PYH3_k127_3245973_13 FAD binding K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 453.0
PYH3_k127_3245973_14 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 443.0
PYH3_k127_3245973_15 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 365.0
PYH3_k127_3245973_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 386.0
PYH3_k127_3245973_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 292.0
PYH3_k127_3245973_18 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 289.0
PYH3_k127_3245973_19 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
PYH3_k127_3245973_2 Glycolate oxidase subunit GlcD K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 6.131e-234 734.0
PYH3_k127_3245973_20 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003026 284.0
PYH3_k127_3245973_21 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004452 276.0
PYH3_k127_3245973_22 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000001052 202.0
PYH3_k127_3245973_23 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000006188 170.0
PYH3_k127_3245973_24 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000005329 172.0
PYH3_k127_3245973_25 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000003349 161.0
PYH3_k127_3245973_26 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000001172 157.0
PYH3_k127_3245973_27 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000002044 132.0
PYH3_k127_3245973_28 - - - - 0.000000000000000000005587 103.0
PYH3_k127_3245973_29 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000002267 84.0
PYH3_k127_3245973_3 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 4.979e-224 703.0
PYH3_k127_3245973_30 Dodecin K09165 - - 0.000000000000000004032 87.0
PYH3_k127_3245973_31 Mitomycin resistance protein K07343 - - 0.00000000000000001167 90.0
PYH3_k127_3245973_32 - - - - 0.000000000000008515 75.0
PYH3_k127_3245973_33 regulator - - - 0.00000000000009136 79.0
PYH3_k127_3245973_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.302e-223 711.0
PYH3_k127_3245973_5 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 579.0
PYH3_k127_3245973_6 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 574.0
PYH3_k127_3245973_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 570.0
PYH3_k127_3245973_8 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 550.0
PYH3_k127_3245973_9 AlkA N-terminal domain K13529 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 525.0
PYH3_k127_3252254_0 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 306.0
PYH3_k127_3252254_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000117 75.0
PYH3_k127_3256346_0 PFAM Type II secretion system protein E K02454,K02652,K12276 - - 6.755e-236 744.0
PYH3_k127_3256346_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 473.0
PYH3_k127_3256346_10 type II secretion system protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001141 202.0
PYH3_k127_3256346_11 TIGRFAM general secretion pathway protein H K02457 - - 0.000000000000000000000000000000000000165 146.0
PYH3_k127_3256346_12 Pfam:N_methyl_2 K02459 - - 0.0000000000000000000000000000000002889 140.0
PYH3_k127_3256346_13 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000000000000000000000000001539 126.0
PYH3_k127_3256346_14 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000000000000001747 119.0
PYH3_k127_3256346_15 - - - - 0.00000000002029 73.0
PYH3_k127_3256346_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 445.0
PYH3_k127_3256346_3 TIGRFAM rfaE bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 405.0
PYH3_k127_3256346_5 Type II secretion system K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 298.0
PYH3_k127_3256346_6 PFAM type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000004818 247.0
PYH3_k127_3256346_7 PFAM Fimbrial assembly family protein K02461 - - 0.00000000000000000000000000000000000000000000000000000000000007703 226.0
PYH3_k127_3256346_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000003458 214.0
PYH3_k127_3256346_9 PFAM type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000002671 217.0
PYH3_k127_3259297_0 IS66 C-terminal element - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003659 259.0
PYH3_k127_3259297_1 COG3436 Transposase and inactivated derivatives K07484 - - 0.00000000000000000000000000000000000000000000002878 177.0
PYH3_k127_3259297_2 COG2801 Transposase and inactivated derivatives - - - 0.000000007515 61.0
PYH3_k127_3265079_0 Histidine kinase K05962 - 2.7.13.1 0.000000000000000000000000000000001901 135.0
PYH3_k127_3265079_1 - - - - 0.000000000000000000000000001045 114.0
PYH3_k127_3265079_2 UPF0391 membrane protein - - - 0.000000000000001295 78.0
PYH3_k127_3265079_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000008347 74.0
PYH3_k127_3265079_5 SMART Transport-associated and nodulation region - - - 0.00000002131 61.0
PYH3_k127_3286949_0 DNA polymerase K02337 - 2.7.7.7 0.0 1150.0
PYH3_k127_3286949_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 561.0
PYH3_k127_3286949_2 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 517.0
PYH3_k127_3286949_3 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 338.0
PYH3_k127_3286949_4 - - - - 0.00000000000000000000000000000000001811 143.0
PYH3_k127_3286949_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000003057 140.0
PYH3_k127_3286949_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000007012 113.0
PYH3_k127_3286949_7 SNARE associated Golgi protein - - - 0.0000000000000000000000002733 112.0
PYH3_k127_3286949_8 Sel1 domain protein repeat-containing protein K07126 - - 0.0000001183 62.0
PYH3_k127_3293736_0 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 319.0
PYH3_k127_3293736_1 helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000009155 236.0
PYH3_k127_3330720_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 1.935e-203 643.0
PYH3_k127_3330720_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 529.0
PYH3_k127_3330720_2 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 346.0
PYH3_k127_3330720_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001311 276.0
PYH3_k127_3330720_4 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000003772 209.0
PYH3_k127_3330720_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000001801 132.0
PYH3_k127_3330720_6 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000665 62.0
PYH3_k127_3367901_0 oxidoreductase K04090 - 1.2.7.8 0.0 1456.0
PYH3_k127_3367901_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.636e-253 801.0
PYH3_k127_3367901_2 FAD dependent oxidoreductase - - - 1.707e-204 646.0
PYH3_k127_3367901_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 389.0
PYH3_k127_3367901_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 356.0
PYH3_k127_3367901_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 292.0
PYH3_k127_3367901_6 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001734 274.0
PYH3_k127_3367901_7 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
PYH3_k127_3367901_8 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000002899 212.0
PYH3_k127_3367901_9 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000005297 158.0
PYH3_k127_3400686_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1744.0
PYH3_k127_3400686_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1216.0
PYH3_k127_3400686_10 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 518.0
PYH3_k127_3400686_11 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 471.0
PYH3_k127_3400686_12 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 464.0
PYH3_k127_3400686_13 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 444.0
PYH3_k127_3400686_14 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 444.0
PYH3_k127_3400686_15 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
PYH3_k127_3400686_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 426.0
PYH3_k127_3400686_17 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 422.0
PYH3_k127_3400686_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 403.0
PYH3_k127_3400686_19 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 404.0
PYH3_k127_3400686_2 Required for chromosome condensation and partitioning K03529 - - 0.0 1115.0
PYH3_k127_3400686_20 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 391.0
PYH3_k127_3400686_21 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 390.0
PYH3_k127_3400686_22 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 392.0
PYH3_k127_3400686_23 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 368.0
PYH3_k127_3400686_24 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 380.0
PYH3_k127_3400686_25 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 342.0
PYH3_k127_3400686_26 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
PYH3_k127_3400686_27 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 325.0
PYH3_k127_3400686_28 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 326.0
PYH3_k127_3400686_29 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003728 277.0
PYH3_k127_3400686_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1021.0
PYH3_k127_3400686_30 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009331 281.0
PYH3_k127_3400686_31 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000365 237.0
PYH3_k127_3400686_32 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000001929 234.0
PYH3_k127_3400686_33 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
PYH3_k127_3400686_34 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000017 226.0
PYH3_k127_3400686_35 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
PYH3_k127_3400686_36 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000001925 216.0
PYH3_k127_3400686_37 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000007789 203.0
PYH3_k127_3400686_38 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000008861 203.0
PYH3_k127_3400686_39 Oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000000006957 170.0
PYH3_k127_3400686_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.491e-288 898.0
PYH3_k127_3400686_40 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000008846 167.0
PYH3_k127_3400686_41 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000006344 155.0
PYH3_k127_3400686_42 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000009605 124.0
PYH3_k127_3400686_43 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000001997 113.0
PYH3_k127_3400686_44 Domain of unknown function (DUF4124) - - - 0.0000000000000000004764 95.0
PYH3_k127_3400686_45 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000001155 79.0
PYH3_k127_3400686_46 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000009066 75.0
PYH3_k127_3400686_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 5.892e-286 897.0
PYH3_k127_3400686_6 ABC transporter C-terminal domain K06158 - - 1.017e-258 811.0
PYH3_k127_3400686_7 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.629e-239 749.0
PYH3_k127_3400686_8 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 539.0
PYH3_k127_3400686_9 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 515.0
PYH3_k127_3414930_0 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000002334 189.0
PYH3_k127_3414930_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000005313 177.0
PYH3_k127_3414930_2 calcium-dependent cysteine-type endopeptidase activity K08578,K08585 - - 0.0001557 54.0
PYH3_k127_3438579_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 459.0
PYH3_k127_3438579_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 380.0
PYH3_k127_3438579_2 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001713 252.0
PYH3_k127_3438579_3 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 K11906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000193 258.0
PYH3_k127_3438579_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000006271 198.0
PYH3_k127_3438579_5 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000008882 173.0
PYH3_k127_3438579_6 CcdB protein K19163 - - 0.00004166 50.0
PYH3_k127_3461621_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 6.286e-205 653.0
PYH3_k127_3461621_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 533.0
PYH3_k127_3461621_2 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 447.0
PYH3_k127_3461621_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001056 119.0
PYH3_k127_3461621_4 - - - - 0.000000000006052 78.0
PYH3_k127_3461621_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000001651 55.0
PYH3_k127_3465479_0 General function prediction only K06020 - 3.6.3.25 1.886e-290 900.0
PYH3_k127_3465479_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 586.0
PYH3_k127_3465479_2 PFAM PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 430.0
PYH3_k127_3465479_3 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000002665 194.0
PYH3_k127_3465479_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001252 110.0
PYH3_k127_3465479_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000001907 84.0
PYH3_k127_3476774_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1105.0
PYH3_k127_3476774_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.757e-316 978.0
PYH3_k127_3476774_10 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 282.0
PYH3_k127_3476774_11 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
PYH3_k127_3476774_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001459 277.0
PYH3_k127_3476774_13 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K03940 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005428 262.0
PYH3_k127_3476774_14 - - - - 0.00000000000000000000000000000000000000000000000002989 187.0
PYH3_k127_3476774_15 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000003821 151.0
PYH3_k127_3476774_16 Twin-arginine translocation pathway signal protein - - - 0.00000000000000000000000000000000003994 141.0
PYH3_k127_3476774_17 Protein of unknown function (DUF541) - - - 0.00000000000000000000000002547 117.0
PYH3_k127_3476774_18 RDD family protein 2 - - - 0.0000000000000000000000002217 111.0
PYH3_k127_3476774_19 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000001447 107.0
PYH3_k127_3476774_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.056e-267 830.0
PYH3_k127_3476774_20 Protein of unknown function (DUF3106) - - - 0.0000000000000000000002547 103.0
PYH3_k127_3476774_21 Protein of unknown function (DUF3619) - - - 0.000000000000000002107 91.0
PYH3_k127_3476774_3 GMC oxidoreductase - - - 4.696e-223 710.0
PYH3_k127_3476774_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 565.0
PYH3_k127_3476774_5 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 470.0
PYH3_k127_3476774_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 396.0
PYH3_k127_3476774_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 323.0
PYH3_k127_3476774_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 290.0
PYH3_k127_3484653_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 295.0
PYH3_k127_3484653_1 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003669 278.0
PYH3_k127_3484653_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004773 275.0
PYH3_k127_3484653_3 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000002665 194.0
PYH3_k127_3484653_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000003197 123.0
PYH3_k127_3485908_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.197e-202 637.0
PYH3_k127_3485908_1 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 467.0
PYH3_k127_3485908_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 266.0
PYH3_k127_3485908_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
PYH3_k127_3485908_4 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000000000000000000000000000000000000000000000808 208.0
PYH3_k127_3485908_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
PYH3_k127_3485908_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000001714 191.0
PYH3_k127_3485908_7 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000131 127.0
PYH3_k127_3485908_8 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000006561 85.0
PYH3_k127_3491233_0 DDE superfamily endonuclease K07494 - - 2.851e-231 717.0
PYH3_k127_3491233_1 Transmembrane family 220, helix - - - 0.0001392 50.0
PYH3_k127_3491233_2 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0002535 46.0
PYH3_k127_3491233_3 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0008146 43.0
PYH3_k127_349587_0 Periplasmic binding protein domain K01999 - - 5.329e-195 614.0
PYH3_k127_349587_1 Urea ABC transporter, urea binding protein K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 601.0
PYH3_k127_349587_2 ANTAR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 329.0
PYH3_k127_349587_3 PFAM Integrase catalytic region K07494 - - 0.000000000000000000000000000001669 122.0
PYH3_k127_349587_4 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000003495 62.0
PYH3_k127_3505517_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 402.0
PYH3_k127_3505517_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 354.0
PYH3_k127_3505517_10 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
PYH3_k127_3505517_11 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000001608 216.0
PYH3_k127_3505517_12 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000444 205.0
PYH3_k127_3505517_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000005529 208.0
PYH3_k127_3505517_14 TPM domain - - - 0.00000000000000000000000000000000000000000000000002619 184.0
PYH3_k127_3505517_15 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000003411 197.0
PYH3_k127_3505517_16 SnoaL-like domain - - - 0.000000000000000000000000005198 111.0
PYH3_k127_3505517_17 Protein of unknown function (DUF2892) - - - 0.00000000000000000000302 95.0
PYH3_k127_3505517_2 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 331.0
PYH3_k127_3505517_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 319.0
PYH3_k127_3505517_4 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 325.0
PYH3_k127_3505517_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 297.0
PYH3_k127_3505517_6 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 289.0
PYH3_k127_3505517_7 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
PYH3_k127_3505517_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001707 249.0
PYH3_k127_3505517_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
PYH3_k127_3586595_0 cytosine deaminase K01485 - 3.5.4.1 4.082e-225 702.0
PYH3_k127_3586595_1 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 433.0
PYH3_k127_3586595_10 BON domain - - - 0.00000000000000000000000000000000000000003528 163.0
PYH3_k127_3586595_11 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000004173 160.0
PYH3_k127_3586595_12 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000007066 126.0
PYH3_k127_3586595_13 Type II secretion system protein B K02451 - - 0.0000000000000000357 86.0
PYH3_k127_3586595_14 Protein of unknown function (DUF3144) - - - 0.000000003287 64.0
PYH3_k127_3586595_15 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00007828 46.0
PYH3_k127_3586595_2 MFS transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 407.0
PYH3_k127_3586595_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 377.0
PYH3_k127_3586595_4 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 361.0
PYH3_k127_3586595_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 327.0
PYH3_k127_3586595_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 299.0
PYH3_k127_3586595_7 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000001664 223.0
PYH3_k127_3586595_8 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000003337 235.0
PYH3_k127_3586595_9 - - - - 0.00000000000000000000000000000000000000000000000000000159 200.0
PYH3_k127_3613973_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 411.0
PYH3_k127_3613973_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 344.0
PYH3_k127_3613973_2 Protein of unknown function (DUF3429) - - - 0.000000000000000007306 91.0
PYH3_k127_3613973_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.00000000000002892 75.0
PYH3_k127_3659011_0 peptidase M24 K01262 - 3.4.11.9 4.842e-255 799.0
PYH3_k127_3659011_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 393.0
PYH3_k127_3659011_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00001739 54.0
PYH3_k127_3659011_11 - - - - 0.0002626 45.0
PYH3_k127_3659011_2 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 385.0
PYH3_k127_3659011_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 360.0
PYH3_k127_3659011_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
PYH3_k127_3659011_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
PYH3_k127_3659011_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
PYH3_k127_3659011_7 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006857 244.0
PYH3_k127_3659011_8 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000001652 237.0
PYH3_k127_3659011_9 Beta-lactamase - - - 0.00000000000000000000000000000000000005493 148.0
PYH3_k127_3663531_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1028.0
PYH3_k127_3663531_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1010.0
PYH3_k127_3663531_10 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 548.0
PYH3_k127_3663531_11 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 544.0
PYH3_k127_3663531_12 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
PYH3_k127_3663531_13 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 501.0
PYH3_k127_3663531_14 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 494.0
PYH3_k127_3663531_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 481.0
PYH3_k127_3663531_16 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 463.0
PYH3_k127_3663531_17 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 439.0
PYH3_k127_3663531_18 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 432.0
PYH3_k127_3663531_19 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 419.0
PYH3_k127_3663531_2 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1007.0
PYH3_k127_3663531_20 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 423.0
PYH3_k127_3663531_21 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 411.0
PYH3_k127_3663531_22 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 410.0
PYH3_k127_3663531_23 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 403.0
PYH3_k127_3663531_24 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 359.0
PYH3_k127_3663531_25 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 352.0
PYH3_k127_3663531_26 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 310.0
PYH3_k127_3663531_27 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 306.0
PYH3_k127_3663531_28 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009671 278.0
PYH3_k127_3663531_29 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001295 270.0
PYH3_k127_3663531_3 Molecular chaperone. Has ATPase activity K04079 - - 6.708e-299 928.0
PYH3_k127_3663531_30 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005567 278.0
PYH3_k127_3663531_31 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000005459 277.0
PYH3_k127_3663531_32 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 263.0
PYH3_k127_3663531_33 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
PYH3_k127_3663531_34 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007913 256.0
PYH3_k127_3663531_35 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 263.0
PYH3_k127_3663531_36 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
PYH3_k127_3663531_37 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000005786 259.0
PYH3_k127_3663531_38 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000007185 250.0
PYH3_k127_3663531_39 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
PYH3_k127_3663531_4 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 8.419e-280 870.0
PYH3_k127_3663531_40 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
PYH3_k127_3663531_41 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000142 223.0
PYH3_k127_3663531_42 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000002194 214.0
PYH3_k127_3663531_43 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000006816 203.0
PYH3_k127_3663531_44 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000003389 207.0
PYH3_k127_3663531_45 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000004174 193.0
PYH3_k127_3663531_46 Haem-degrading K11477 - - 0.0000000000000000000000000000000000000000000000000004211 196.0
PYH3_k127_3663531_47 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000006449 209.0
PYH3_k127_3663531_48 DUF218 domain - - - 0.00000000000000000000000000000000000000000000008902 178.0
PYH3_k127_3663531_49 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000002184 169.0
PYH3_k127_3663531_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 8.697e-278 888.0
PYH3_k127_3663531_50 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000001236 159.0
PYH3_k127_3663531_51 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000001222 157.0
PYH3_k127_3663531_52 Copper resistance protein D - - - 0.0000000000000000000000000000000000002367 148.0
PYH3_k127_3663531_53 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000004408 141.0
PYH3_k127_3663531_54 membrane - - - 0.000000000000000000000000000000000001548 147.0
PYH3_k127_3663531_55 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000002563 130.0
PYH3_k127_3663531_56 Protein conserved in bacteria K09705 - - 0.000000000000000000000000000003663 128.0
PYH3_k127_3663531_57 AraC-like ligand binding domain - - - 0.0000000000000000000000000004455 116.0
PYH3_k127_3663531_58 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000007302 116.0
PYH3_k127_3663531_59 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000003333 99.0
PYH3_k127_3663531_6 PFAM AMP-dependent synthetase and ligase K00666 - - 1.77e-271 844.0
PYH3_k127_3663531_60 TM2 domain - - - 0.0000000000000000000008757 101.0
PYH3_k127_3663531_61 - - - - 0.00000000000000000001992 98.0
PYH3_k127_3663531_62 NlpC P60 family protein K19303 - - 0.000000001481 62.0
PYH3_k127_3663531_63 NlpC/P60 family - - - 0.0004972 46.0
PYH3_k127_3663531_7 Cysteine-rich domain - - - 1.302e-204 646.0
PYH3_k127_3663531_8 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 611.0
PYH3_k127_3663531_9 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 610.0
PYH3_k127_3676957_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1514.0
PYH3_k127_3676957_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1298.0
PYH3_k127_3676957_10 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 503.0
PYH3_k127_3676957_11 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 471.0
PYH3_k127_3676957_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 445.0
PYH3_k127_3676957_13 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 404.0
PYH3_k127_3676957_14 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 404.0
PYH3_k127_3676957_15 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 396.0
PYH3_k127_3676957_16 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 373.0
PYH3_k127_3676957_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 338.0
PYH3_k127_3676957_18 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 318.0
PYH3_k127_3676957_19 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 310.0
PYH3_k127_3676957_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 9.765e-222 694.0
PYH3_k127_3676957_20 squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
PYH3_k127_3676957_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 289.0
PYH3_k127_3676957_22 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001143 273.0
PYH3_k127_3676957_23 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005793 275.0
PYH3_k127_3676957_24 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
PYH3_k127_3676957_25 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000005998 237.0
PYH3_k127_3676957_26 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000009982 217.0
PYH3_k127_3676957_27 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000001143 223.0
PYH3_k127_3676957_28 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000007074 176.0
PYH3_k127_3676957_29 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000003948 150.0
PYH3_k127_3676957_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.426e-219 695.0
PYH3_k127_3676957_30 Peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000008272 149.0
PYH3_k127_3676957_31 - - - - 0.000000000000000002164 92.0
PYH3_k127_3676957_32 Protein of unknown function (DUF465) - - - 0.00000000000000002227 83.0
PYH3_k127_3676957_33 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000001973 80.0
PYH3_k127_3676957_34 - - - - 0.0002429 45.0
PYH3_k127_3676957_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.077e-216 682.0
PYH3_k127_3676957_5 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.995e-206 658.0
PYH3_k127_3676957_6 Belongs to the thiolase family K00626 - 2.3.1.9 1.714e-197 629.0
PYH3_k127_3676957_7 HELICc2 K03722 - 3.6.4.12 3.282e-196 636.0
PYH3_k127_3676957_8 Belongs to the thiolase family K00626 - 2.3.1.9 7.301e-195 613.0
PYH3_k127_3676957_9 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 562.0
PYH3_k127_369094_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 5.459e-266 841.0
PYH3_k127_369094_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 516.0
PYH3_k127_369094_10 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000001491 154.0
PYH3_k127_369094_11 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000009432 144.0
PYH3_k127_369094_12 TonB C terminal K03646 - - 0.00000000000000000000002835 111.0
PYH3_k127_369094_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 463.0
PYH3_k127_369094_3 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 408.0
PYH3_k127_369094_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 394.0
PYH3_k127_369094_5 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 304.0
PYH3_k127_369094_6 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 303.0
PYH3_k127_369094_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
PYH3_k127_369094_8 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000001192 202.0
PYH3_k127_369094_9 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000751 152.0
PYH3_k127_3705853_0 synthetase K01907 - 6.2.1.16 1.277e-284 893.0
PYH3_k127_3705853_1 abc transporter K15738 - - 1.701e-208 670.0
PYH3_k127_3705853_10 PFAM MmgE PrpD family protein - - - 0.00000000000000000000594 95.0
PYH3_k127_3705853_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 436.0
PYH3_k127_3705853_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 430.0
PYH3_k127_3705853_4 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 395.0
PYH3_k127_3705853_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 381.0
PYH3_k127_3705853_6 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 296.0
PYH3_k127_3705853_7 Glycine-zipper domain - - - 0.00000000000000000000000000000000000001926 150.0
PYH3_k127_3705853_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000003952 122.0
PYH3_k127_3705853_9 - - - - 0.0000000000000000000003117 101.0
PYH3_k127_3723623_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 474.0
PYH3_k127_3723623_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 401.0
PYH3_k127_3723623_2 Short-chain dehydrogenase reductase sdr K22185 - 1.1.1.175 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
PYH3_k127_3723623_3 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000001607 176.0
PYH3_k127_3723623_4 Biotin-requiring enzyme - - - 0.0000000000000000002293 91.0
PYH3_k127_3744178_0 Dehydratase family K01690 - 4.2.1.12 2.391e-273 852.0
PYH3_k127_3744178_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.534e-204 649.0
PYH3_k127_3744178_2 Maltoporin (phage lambda and maltose receptor) K02024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 407.0
PYH3_k127_3744178_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 336.0
PYH3_k127_3744178_4 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000002345 223.0
PYH3_k127_3744178_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000001387 160.0
PYH3_k127_3744178_6 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000008303 78.0
PYH3_k127_3744178_7 Flp pilus assembly protein TadD, contains TPR repeats - - - 0.000004053 57.0
PYH3_k127_3744178_8 PFAM Transposase DDE domain - - - 0.000008409 48.0
PYH3_k127_3784552_0 Tricorn protease homolog K08676 - - 0.0 1099.0
PYH3_k127_3784552_1 Male sterility protein - - - 0.0 1018.0
PYH3_k127_3784552_10 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 314.0
PYH3_k127_3784552_11 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 311.0
PYH3_k127_3784552_12 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000007837 220.0
PYH3_k127_3784552_13 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000292 181.0
PYH3_k127_3784552_14 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000007465 176.0
PYH3_k127_3784552_15 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000426 154.0
PYH3_k127_3784552_16 PFAM poly granule associated family protein - - - 0.0000000000000000000000000000000000002613 146.0
PYH3_k127_3784552_17 GtrA-like protein - - - 0.0000000000000000000000000000000002294 142.0
PYH3_k127_3784552_18 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000001529 76.0
PYH3_k127_3784552_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 7.799e-248 779.0
PYH3_k127_3784552_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.322e-220 698.0
PYH3_k127_3784552_4 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 4.516e-220 708.0
PYH3_k127_3784552_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 495.0
PYH3_k127_3784552_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 486.0
PYH3_k127_3784552_7 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 427.0
PYH3_k127_3784552_8 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH3_k127_3784552_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
PYH3_k127_3800249_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 404.0
PYH3_k127_3800249_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 383.0
PYH3_k127_3800249_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000003283 227.0
PYH3_k127_3800249_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000008983 128.0
PYH3_k127_3800249_4 - - - - 0.000001995 50.0
PYH3_k127_3820574_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 4.712e-274 854.0
PYH3_k127_3820574_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 443.0
PYH3_k127_3820574_2 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 351.0
PYH3_k127_3820574_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 300.0
PYH3_k127_3820574_4 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 309.0
PYH3_k127_3820574_5 Proteasome subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002457 272.0
PYH3_k127_3820574_6 Ankyrin repeats (3 copies) K06867,K21440 - - 0.0000000000000000000000000000000000000000000000001688 184.0
PYH3_k127_3820574_7 - - - - 0.0000000000000000000000000000000000000001163 160.0
PYH3_k127_3820574_8 PQQ enzyme repeat - - - 0.000000000000000000000000000000168 129.0
PYH3_k127_38294_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1730.0
PYH3_k127_38294_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.885e-253 786.0
PYH3_k127_38294_10 LysM domain K08086 - - 0.0000000000000000000000000000000000005111 145.0
PYH3_k127_38294_11 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000197 156.0
PYH3_k127_38294_12 gluconokinase activity - - - 0.000000000000000000000004702 106.0
PYH3_k127_38294_13 Entericidin EcnA/B family - - - 0.00000005334 55.0
PYH3_k127_38294_14 Domain of unknown function (DUF1127) - - - 0.0003703 43.0
PYH3_k127_38294_15 PFAM Integrase catalytic region K07497 - - 0.0005996 51.0
PYH3_k127_38294_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 587.0
PYH3_k127_38294_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 581.0
PYH3_k127_38294_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 568.0
PYH3_k127_38294_5 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 496.0
PYH3_k127_38294_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 427.0
PYH3_k127_38294_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
PYH3_k127_38294_8 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
PYH3_k127_38294_9 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006586 297.0
PYH3_k127_3832723_0 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000000000000000005209 247.0
PYH3_k127_3832723_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000003466 95.0
PYH3_k127_383498_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 5.186e-199 631.0
PYH3_k127_383498_1 binding-protein-dependent transport systems inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 593.0
PYH3_k127_383498_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 535.0
PYH3_k127_383498_3 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000004471 206.0
PYH3_k127_3847199_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.017e-227 719.0
PYH3_k127_3847199_1 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 608.0
PYH3_k127_3847199_10 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000005547 155.0
PYH3_k127_3847199_11 cell division protein - - - 0.0000000000000000000000000003017 126.0
PYH3_k127_3847199_12 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000001614 94.0
PYH3_k127_3847199_13 LysR substrate binding domain K03566 - - 0.000000003597 65.0
PYH3_k127_3847199_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 506.0
PYH3_k127_3847199_3 Binding-protein-dependent transport system inner membrane component K10009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 426.0
PYH3_k127_3847199_4 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 374.0
PYH3_k127_3847199_5 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 358.0
PYH3_k127_3847199_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
PYH3_k127_3847199_7 Pfam Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 312.0
PYH3_k127_3847199_8 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000009296 218.0
PYH3_k127_3847199_9 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000001169 187.0
PYH3_k127_3852585_0 o-acetylhomoserine K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 551.0
PYH3_k127_3852585_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001894 265.0
PYH3_k127_3852585_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
PYH3_k127_3852585_3 Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004512 234.0
PYH3_k127_3857590_0 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 586.0
PYH3_k127_3857590_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 514.0
PYH3_k127_3857590_2 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
PYH3_k127_3857590_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003406 231.0
PYH3_k127_3857590_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000713 233.0
PYH3_k127_3857590_5 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.00000006605 54.0
PYH3_k127_3895274_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 479.0
PYH3_k127_3895274_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 463.0
PYH3_k127_3895274_2 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 271.0
PYH3_k127_3895274_3 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000000000000000000000000000003293 235.0
PYH3_k127_3895274_4 General secretion pathway protein K02672 - - 0.0000000000000000000000000000004483 133.0
PYH3_k127_3895274_5 type IV pilus modification protein PilV - - - 0.0000000000000000000000000001672 133.0
PYH3_k127_3895274_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000012 108.0
PYH3_k127_3895274_7 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000001876 78.0
PYH3_k127_3895274_8 Type II transport protein GspH K08084 - - 0.0000000003746 68.0
PYH3_k127_3895331_0 General secretion pathway protein K02672 - - 0.0000000000000000000000000000000000000006573 159.0
PYH3_k127_3895331_1 type IV pilus modification protein PilV - - - 0.0000000000000000000005144 106.0
PYH3_k127_3895331_2 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000009749 98.0
PYH3_k127_3895331_3 Pilus assembly protein PilX - - - 0.0000000000000001226 93.0
PYH3_k127_3895331_4 Type II transport protein GspH K08084 - - 0.00000000000004764 80.0
PYH3_k127_3915749_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1564.0
PYH3_k127_3915749_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 5e-324 998.0
PYH3_k127_3915749_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.444e-308 960.0
PYH3_k127_3915749_3 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 3.912e-240 750.0
PYH3_k127_3915749_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
PYH3_k127_3915749_5 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 504.0
PYH3_k127_3972048_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1033.0
PYH3_k127_3972048_1 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.17e-303 945.0
PYH3_k127_3972048_10 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 318.0
PYH3_k127_3972048_11 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 291.0
PYH3_k127_3972048_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 287.0
PYH3_k127_3972048_13 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 284.0
PYH3_k127_3972048_14 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001417 280.0
PYH3_k127_3972048_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006969 291.0
PYH3_k127_3972048_16 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004182 252.0
PYH3_k127_3972048_18 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000001911 191.0
PYH3_k127_3972048_19 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000009579 179.0
PYH3_k127_3972048_2 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 560.0
PYH3_k127_3972048_20 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000009897 181.0
PYH3_k127_3972048_21 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.0000000000000000000000000000004853 128.0
PYH3_k127_3972048_22 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000002544 96.0
PYH3_k127_3972048_24 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000008223 86.0
PYH3_k127_3972048_25 chaperone-mediated protein folding - - - 0.000000000001159 79.0
PYH3_k127_3972048_3 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 524.0
PYH3_k127_3972048_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 474.0
PYH3_k127_3972048_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 460.0
PYH3_k127_3972048_6 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 448.0
PYH3_k127_3972048_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 462.0
PYH3_k127_3972048_8 Aldo/keto reductase family - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 351.0
PYH3_k127_3972048_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 340.0
PYH3_k127_3972356_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1485.0
PYH3_k127_3972356_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 9.193e-318 980.0
PYH3_k127_3972356_10 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 451.0
PYH3_k127_3972356_11 DNA recombination protein, rmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 464.0
PYH3_k127_3972356_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 400.0
PYH3_k127_3972356_13 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 352.0
PYH3_k127_3972356_14 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
PYH3_k127_3972356_15 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 279.0
PYH3_k127_3972356_16 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001512 254.0
PYH3_k127_3972356_17 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000000000001206 198.0
PYH3_k127_3972356_18 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000000147 193.0
PYH3_k127_3972356_19 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000000000000000000001895 177.0
PYH3_k127_3972356_2 FtsX-like permease family K02004 - - 3.19e-285 898.0
PYH3_k127_3972356_20 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000000001203 163.0
PYH3_k127_3972356_21 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000004045 106.0
PYH3_k127_3972356_22 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000008757 104.0
PYH3_k127_3972356_23 PIN domain - - - 0.000000000000000000105 102.0
PYH3_k127_3972356_24 3' exoribonuclease, RNase T-like - - - 0.00000001602 67.0
PYH3_k127_3972356_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.795e-249 773.0
PYH3_k127_3972356_4 MmgE/PrpD family K01720 - 4.2.1.79 4.68e-249 776.0
PYH3_k127_3972356_5 acyl-CoA dehydrogenase activity - - - 3.057e-210 670.0
PYH3_k127_3972356_6 Ketoacyl-synthetase C-terminal extension - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 605.0
PYH3_k127_3972356_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 557.0
PYH3_k127_3972356_8 Aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009279 492.0
PYH3_k127_3972356_9 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 458.0
PYH3_k127_3979169_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 497.0
PYH3_k127_3979169_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 456.0
PYH3_k127_3979169_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 452.0
PYH3_k127_3979169_3 Integrase - - - 0.0000000000000000006304 89.0
PYH3_k127_4005720_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1165.0
PYH3_k127_4005720_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 569.0
PYH3_k127_4005720_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
PYH3_k127_4005720_3 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000006834 180.0
PYH3_k127_4005720_4 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000005684 137.0
PYH3_k127_4005720_5 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000006154 89.0
PYH3_k127_4005720_6 - - - - 0.00000000000001006 76.0
PYH3_k127_4017042_0 PFAM ABC transporter K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 436.0
PYH3_k127_4017042_1 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 421.0
PYH3_k127_4017042_2 COG1176 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 382.0
PYH3_k127_4017042_3 transcriptional - - - 0.0000000000000000000000000000000000000000004127 168.0
PYH3_k127_4017042_4 Acyl-transferase - - - 0.00000000000000000000000006344 109.0
PYH3_k127_4017042_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000855 101.0
PYH3_k127_4071518_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1013.0
PYH3_k127_4071518_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 574.0
PYH3_k127_4071518_10 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.000006504 51.0
PYH3_k127_4071518_11 - - - - 0.00003979 53.0
PYH3_k127_4071518_2 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 515.0
PYH3_k127_4071518_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 478.0
PYH3_k127_4071518_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000007116 210.0
PYH3_k127_4071518_5 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000001348 209.0
PYH3_k127_4071518_6 Protein of unknown function (DUF3579) - - - 0.00000000000000000000000000000000000002675 147.0
PYH3_k127_4071518_7 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000003579 105.0
PYH3_k127_4071518_8 diguanylate cyclase - - - 0.000000000000000000000004332 118.0
PYH3_k127_4071518_9 Bacterial transcriptional activator domain - - - 0.00000000000004172 82.0
PYH3_k127_4077203_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1403.0
PYH3_k127_4077203_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.658e-304 940.0
PYH3_k127_4077203_10 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 464.0
PYH3_k127_4077203_11 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 397.0
PYH3_k127_4077203_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 402.0
PYH3_k127_4077203_13 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 375.0
PYH3_k127_4077203_14 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
PYH3_k127_4077203_15 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 335.0
PYH3_k127_4077203_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 331.0
PYH3_k127_4077203_17 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 287.0
PYH3_k127_4077203_18 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009644 269.0
PYH3_k127_4077203_19 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000008738 266.0
PYH3_k127_4077203_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.118e-291 899.0
PYH3_k127_4077203_20 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002451 268.0
PYH3_k127_4077203_21 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000003322 226.0
PYH3_k127_4077203_22 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000168 184.0
PYH3_k127_4077203_23 - - - - 0.0000000000000000000000000000000000000000001618 174.0
PYH3_k127_4077203_24 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000001128 153.0
PYH3_k127_4077203_25 Ribosomal protein L31 K02909 - - 0.0000000000000000000000000000004484 131.0
PYH3_k127_4077203_26 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000002389 105.0
PYH3_k127_4077203_27 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000002601 81.0
PYH3_k127_4077203_28 Helix-hairpin-helix motif K02237 - - 0.000000000006319 74.0
PYH3_k127_4077203_29 Lipopolysaccharide assembly protein A domain K08992 - - 0.000002842 56.0
PYH3_k127_4077203_3 Domain of Unknown Function (DUF748) - - - 3.418e-240 784.0
PYH3_k127_4077203_30 cysteine synthase K01738 - 2.5.1.47 0.0004679 46.0
PYH3_k127_4077203_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.809e-239 745.0
PYH3_k127_4077203_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 518.0
PYH3_k127_4077203_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 502.0
PYH3_k127_4077203_7 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 483.0
PYH3_k127_4077203_8 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 475.0
PYH3_k127_4077203_9 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 477.0
PYH3_k127_4094361_0 DNA polymerase X family K02347 - - 5.953e-235 739.0
PYH3_k127_4094361_1 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 449.0
PYH3_k127_4094361_10 response regulator - - - 0.00000000000000000000000006086 121.0
PYH3_k127_4094361_11 - - - - 0.00000000000000000008763 90.0
PYH3_k127_4094361_12 Immunoglobulin - - - 0.00000000000002026 78.0
PYH3_k127_4094361_13 - - - - 0.000000000005467 76.0
PYH3_k127_4094361_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 435.0
PYH3_k127_4094361_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 347.0
PYH3_k127_4094361_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 286.0
PYH3_k127_4094361_5 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002891 243.0
PYH3_k127_4094361_6 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000000000002411 201.0
PYH3_k127_4094361_7 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000002827 201.0
PYH3_k127_4094361_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000001392 146.0
PYH3_k127_4094361_9 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000006014 140.0
PYH3_k127_4195861_0 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 567.0
PYH3_k127_4195861_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 457.0
PYH3_k127_4195861_2 Copper resistance protein D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 366.0
PYH3_k127_4195861_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 313.0
PYH3_k127_4195861_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 257.0
PYH3_k127_4195861_5 CopC domain - - - 0.00000000000000000000000001042 119.0
PYH3_k127_4195861_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000001093 59.0
PYH3_k127_4195861_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000006263 54.0
PYH3_k127_4205673_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 461.0
PYH3_k127_4205673_1 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 390.0
PYH3_k127_4205673_2 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 295.0
PYH3_k127_4205673_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
PYH3_k127_4205673_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000009521 211.0
PYH3_k127_4205673_5 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000222 130.0
PYH3_k127_4205673_6 Phosphopantetheine attachment site - - - 0.00000000000000000009043 99.0
PYH3_k127_4205673_7 Transglutaminase/protease-like homologues - - - 0.000000001814 62.0
PYH3_k127_4221369_0 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 315.0
PYH3_k127_4221369_1 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001525 281.0
PYH3_k127_4221369_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000001405 174.0
PYH3_k127_4294477_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1321.0
PYH3_k127_4294477_1 Domain of unknown function (DUF5117) - - - 2.668e-213 697.0
PYH3_k127_4294477_2 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003879 266.0
PYH3_k127_4294477_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009997 229.0
PYH3_k127_4296042_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 306.0
PYH3_k127_4296042_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000001074 236.0
PYH3_k127_4325622_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
PYH3_k127_4325622_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 510.0
PYH3_k127_4325622_10 Protein of unknown function (DUF2846) - - - 0.000000000000000000001285 99.0
PYH3_k127_4325622_11 Putative zinc ribbon domain - - - 0.00000000000000000002015 94.0
PYH3_k127_4325622_2 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 495.0
PYH3_k127_4325622_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 409.0
PYH3_k127_4325622_4 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 399.0
PYH3_k127_4325622_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 388.0
PYH3_k127_4325622_6 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 372.0
PYH3_k127_4325622_7 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000001799 199.0
PYH3_k127_4325622_8 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000002793 190.0
PYH3_k127_4325622_9 - - - - 0.00000000000000000000000000000000000000000252 167.0
PYH3_k127_4392896_0 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000003513 163.0
PYH3_k127_4392896_1 WD40 repeat, subgroup - - - 0.000000000000000000000000000001538 140.0
PYH3_k127_4392896_2 - - - - 0.0007961 48.0
PYH3_k127_4404816_0 FAD dependent oxidoreductase central domain - - - 0.0 1323.0
PYH3_k127_4404816_1 Peptidase M61 - - - 4.399e-209 666.0
PYH3_k127_4404816_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 437.0
PYH3_k127_4404816_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 381.0
PYH3_k127_4404816_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000001016 179.0
PYH3_k127_4404816_5 - - - - 0.00000000000000000002396 103.0
PYH3_k127_4404816_6 - - - - 0.00000000000009416 76.0
PYH3_k127_4404816_7 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000001912 53.0
PYH3_k127_4427320_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1007.0
PYH3_k127_4427320_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.628e-299 939.0
PYH3_k127_4427320_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.698e-216 691.0
PYH3_k127_4427320_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 578.0
PYH3_k127_4427320_4 PFAM extracellular solute-binding protein family 1 K17315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 502.0
PYH3_k127_4427320_5 ABC transporter K10111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 327.0
PYH3_k127_4427320_6 - - - - 0.000000000000000000000000000000000000000000005466 177.0
PYH3_k127_4441344_0 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 413.0
PYH3_k127_4441344_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 321.0
PYH3_k127_4441344_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 266.0
PYH3_k127_4441344_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000603 196.0
PYH3_k127_4441344_4 Transposase K00957,K07497 - 2.7.7.4 0.0000000000000897 83.0
PYH3_k127_4509409_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1508.0
PYH3_k127_4509409_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1298.0
PYH3_k127_4509409_10 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 5.183e-209 653.0
PYH3_k127_4509409_100 zinc-ribbon domain - - - 0.000000000000000000000000000000000003209 151.0
PYH3_k127_4509409_101 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000001785 137.0
PYH3_k127_4509409_102 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000001402 144.0
PYH3_k127_4509409_103 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000000000000000000004038 141.0
PYH3_k127_4509409_104 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000000963 128.0
PYH3_k127_4509409_105 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000001002 127.0
PYH3_k127_4509409_106 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000001381 130.0
PYH3_k127_4509409_107 KTSC domain - - - 0.000000000000000000000000000007043 119.0
PYH3_k127_4509409_108 Flagellar protein FliS K02422 - - 0.0000000000000000000000000008467 118.0
PYH3_k127_4509409_109 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000000001112 110.0
PYH3_k127_4509409_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.403e-208 656.0
PYH3_k127_4509409_110 membrane K06077 - - 0.0000000000000000000000001844 111.0
PYH3_k127_4509409_111 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000001015 102.0
PYH3_k127_4509409_112 Histidine kinase-like ATPase domain - - - 0.0000000000000000000002882 101.0
PYH3_k127_4509409_113 Flagellar protein FliT K02423 - - 0.00000000000000000106 92.0
PYH3_k127_4509409_114 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000002949 83.0
PYH3_k127_4509409_115 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000000000000009552 84.0
PYH3_k127_4509409_116 - - - - 0.0000000000000001054 90.0
PYH3_k127_4509409_117 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000006559 81.0
PYH3_k127_4509409_118 Malic enzyme, NAD binding domain K00027,K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40 0.000000000000001636 79.0
PYH3_k127_4509409_119 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000006975 78.0
PYH3_k127_4509409_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.109e-205 649.0
PYH3_k127_4509409_120 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000005895 72.0
PYH3_k127_4509409_121 Flagellar hook-length control protein FliK - - - 0.0000000005745 71.0
PYH3_k127_4509409_122 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000007877 64.0
PYH3_k127_4509409_123 Belongs to the ParA family K04562 - - 0.000000008659 66.0
PYH3_k127_4509409_124 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000128 54.0
PYH3_k127_4509409_125 - K06950 - - 0.000002712 59.0
PYH3_k127_4509409_126 Patatin-like phospholipase K07001 - - 0.000009605 52.0
PYH3_k127_4509409_127 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000107 56.0
PYH3_k127_4509409_128 Malic enzyme K00029 - 1.1.1.40 0.00001774 47.0
PYH3_k127_4509409_129 FlaG protein K06603 - - 0.00003329 51.0
PYH3_k127_4509409_13 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.389e-203 654.0
PYH3_k127_4509409_130 malic enzyme K00029 - 1.1.1.40 0.00007774 45.0
PYH3_k127_4509409_131 - - - - 0.0002231 46.0
PYH3_k127_4509409_132 Protein of unknown function (DUF721) - - - 0.0002508 50.0
PYH3_k127_4509409_14 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 607.0
PYH3_k127_4509409_15 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 610.0
PYH3_k127_4509409_16 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 579.0
PYH3_k127_4509409_17 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 555.0
PYH3_k127_4509409_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 591.0
PYH3_k127_4509409_19 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 556.0
PYH3_k127_4509409_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.158e-275 858.0
PYH3_k127_4509409_20 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 546.0
PYH3_k127_4509409_21 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 561.0
PYH3_k127_4509409_22 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 542.0
PYH3_k127_4509409_23 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 550.0
PYH3_k127_4509409_24 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 536.0
PYH3_k127_4509409_25 Sigma-54 interaction domain K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 542.0
PYH3_k127_4509409_26 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 531.0
PYH3_k127_4509409_27 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 538.0
PYH3_k127_4509409_28 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 497.0
PYH3_k127_4509409_29 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 497.0
PYH3_k127_4509409_3 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.339e-268 844.0
PYH3_k127_4509409_30 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 502.0
PYH3_k127_4509409_31 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 502.0
PYH3_k127_4509409_32 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 483.0
PYH3_k127_4509409_33 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 457.0
PYH3_k127_4509409_34 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 466.0
PYH3_k127_4509409_35 Flagellar basal body rod protein K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 445.0
PYH3_k127_4509409_36 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 441.0
PYH3_k127_4509409_37 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 436.0
PYH3_k127_4509409_38 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 421.0
PYH3_k127_4509409_39 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 407.0
PYH3_k127_4509409_4 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 9.263e-259 804.0
PYH3_k127_4509409_40 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 399.0
PYH3_k127_4509409_41 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 410.0
PYH3_k127_4509409_42 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 395.0
PYH3_k127_4509409_43 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 388.0
PYH3_k127_4509409_44 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 383.0
PYH3_k127_4509409_45 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 377.0
PYH3_k127_4509409_46 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 377.0
PYH3_k127_4509409_47 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 354.0
PYH3_k127_4509409_48 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
PYH3_k127_4509409_49 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 344.0
PYH3_k127_4509409_5 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.636e-251 779.0
PYH3_k127_4509409_50 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 341.0
PYH3_k127_4509409_51 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH3_k127_4509409_52 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 319.0
PYH3_k127_4509409_53 Periplasmic sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 343.0
PYH3_k127_4509409_54 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 317.0
PYH3_k127_4509409_55 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 329.0
PYH3_k127_4509409_56 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 319.0
PYH3_k127_4509409_57 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
PYH3_k127_4509409_58 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 310.0
PYH3_k127_4509409_59 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 322.0
PYH3_k127_4509409_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 4.861e-246 771.0
PYH3_k127_4509409_60 FHA Domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
PYH3_k127_4509409_61 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 289.0
PYH3_k127_4509409_62 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 294.0
PYH3_k127_4509409_63 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 291.0
PYH3_k127_4509409_64 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000612 313.0
PYH3_k127_4509409_65 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001216 281.0
PYH3_k127_4509409_66 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005057 291.0
PYH3_k127_4509409_67 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
PYH3_k127_4509409_68 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
PYH3_k127_4509409_69 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 271.0
PYH3_k127_4509409_7 RNB K01147 - 3.1.13.1 5.269e-219 697.0
PYH3_k127_4509409_70 Rod binding protein K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003003 280.0
PYH3_k127_4509409_71 Flagellar basal-body rod protein FlgF K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
PYH3_k127_4509409_72 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003506 265.0
PYH3_k127_4509409_73 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008442 265.0
PYH3_k127_4509409_74 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 254.0
PYH3_k127_4509409_75 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
PYH3_k127_4509409_76 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000007578 249.0
PYH3_k127_4509409_77 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000001078 233.0
PYH3_k127_4509409_78 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005426 231.0
PYH3_k127_4509409_79 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000005152 222.0
PYH3_k127_4509409_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.454e-213 677.0
PYH3_k127_4509409_80 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000000000000000000000000000000000003813 231.0
PYH3_k127_4509409_81 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000003563 214.0
PYH3_k127_4509409_82 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000005059 222.0
PYH3_k127_4509409_83 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000002581 201.0
PYH3_k127_4509409_84 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000005757 195.0
PYH3_k127_4509409_85 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
PYH3_k127_4509409_86 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001419 190.0
PYH3_k127_4509409_87 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000001589 196.0
PYH3_k127_4509409_88 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000004369 187.0
PYH3_k127_4509409_89 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000002467 185.0
PYH3_k127_4509409_9 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 6.566e-213 677.0
PYH3_k127_4509409_90 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000002557 178.0
PYH3_k127_4509409_91 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000000000000000278 175.0
PYH3_k127_4509409_92 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000006331 171.0
PYH3_k127_4509409_93 YbaK prolyl-tRNA synthetase associated - - - 0.00000000000000000000000000000000000000000006364 170.0
PYH3_k127_4509409_94 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000002297 170.0
PYH3_k127_4509409_95 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000001819 159.0
PYH3_k127_4509409_96 YGGT family K02221 - - 0.00000000000000000000000000000000000000001019 160.0
PYH3_k127_4509409_97 mRNA catabolic process - - - 0.0000000000000000000000000000000000000002019 157.0
PYH3_k127_4509409_98 Redoxin domain protein - - - 0.000000000000000000000000000000000000005058 152.0
PYH3_k127_4509409_99 LuxR family transcriptional regulator K13041 - - 0.00000000000000000000000000000000000002032 152.0
PYH3_k127_4576331_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3e-323 998.0
PYH3_k127_4576331_1 Belongs to the CarB family K01955 - 6.3.5.5 9.945e-317 976.0
PYH3_k127_4576331_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001463 284.0
PYH3_k127_4576331_11 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001913 285.0
PYH3_k127_4576331_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001974 254.0
PYH3_k127_4576331_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000002182 228.0
PYH3_k127_4576331_14 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000001538 187.0
PYH3_k127_4576331_15 CRS1_YhbY K07574 - - 0.000000000000000000000000000000001666 134.0
PYH3_k127_4576331_16 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000006971 130.0
PYH3_k127_4576331_2 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 5.286e-204 640.0
PYH3_k127_4576331_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 615.0
PYH3_k127_4576331_4 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 510.0
PYH3_k127_4576331_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 483.0
PYH3_k127_4576331_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 437.0
PYH3_k127_4576331_7 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 426.0
PYH3_k127_4576331_8 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 407.0
PYH3_k127_4576331_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 309.0
PYH3_k127_4593772_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 1.045e-287 897.0
PYH3_k127_4593772_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.552e-194 614.0
PYH3_k127_4593772_10 CobW/HypB/UreG, nucleotide-binding domain - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0008715 51.0
PYH3_k127_4593772_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 587.0
PYH3_k127_4593772_3 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 564.0
PYH3_k127_4593772_4 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 353.0
PYH3_k127_4593772_5 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 295.0
PYH3_k127_4593772_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006206 282.0
PYH3_k127_4593772_7 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
PYH3_k127_4593772_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000001419 269.0
PYH3_k127_4593772_9 DDE superfamily endonuclease - - - 0.000000000000000000001211 94.0
PYH3_k127_4607765_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.671e-303 949.0
PYH3_k127_4607765_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.048e-242 764.0
PYH3_k127_4607765_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002645 190.0
PYH3_k127_4607765_11 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.00000000000000000000000000000000000000000000007579 183.0
PYH3_k127_4607765_12 Belongs to the 'phage' integrase family - - - 0.00000000000000001718 91.0
PYH3_k127_4607765_13 LAO AO transport system ATPase K07588 - - 0.0000000002287 63.0
PYH3_k127_4607765_14 - - - - 0.00005664 47.0
PYH3_k127_4607765_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.083e-214 672.0
PYH3_k127_4607765_3 Extracellular solute-binding protein K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 599.0
PYH3_k127_4607765_4 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 596.0
PYH3_k127_4607765_5 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 498.0
PYH3_k127_4607765_6 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 452.0
PYH3_k127_4607765_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 412.0
PYH3_k127_4607765_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000002627 226.0
PYH3_k127_4607765_9 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000008724 208.0
PYH3_k127_468784_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1249.0
PYH3_k127_468784_1 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007217 274.0
PYH3_k127_468784_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000001669 122.0
PYH3_k127_468784_3 PEP-CTERM motif - - - 0.0002024 51.0
PYH3_k127_4712316_0 Ammonium transporter K03320 - - 5.473e-229 723.0
PYH3_k127_4712316_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 3.351e-226 710.0
PYH3_k127_4712316_10 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 363.0
PYH3_k127_4712316_11 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 372.0
PYH3_k127_4712316_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH3_k127_4712316_13 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009521 263.0
PYH3_k127_4712316_14 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
PYH3_k127_4712316_15 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
PYH3_k127_4712316_16 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001587 236.0
PYH3_k127_4712316_17 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000844 233.0
PYH3_k127_4712316_18 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
PYH3_k127_4712316_19 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000003783 230.0
PYH3_k127_4712316_2 Glutamate-cysteine ligase K01919 - 6.3.2.2 4.679e-198 629.0
PYH3_k127_4712316_20 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000000006701 214.0
PYH3_k127_4712316_21 Auxin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000002269 201.0
PYH3_k127_4712316_22 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000006841 195.0
PYH3_k127_4712316_23 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000002034 155.0
PYH3_k127_4712316_24 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000002833 116.0
PYH3_k127_4712316_25 Membrane fusogenic activity K09806 - - 0.000000000000000002329 89.0
PYH3_k127_4712316_26 Domain of unknown function (DUF4124) - - - 0.0000000000002254 79.0
PYH3_k127_4712316_27 Glycosyl transferases group 1 - - - 0.000000101 61.0
PYH3_k127_4712316_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 602.0
PYH3_k127_4712316_4 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 587.0
PYH3_k127_4712316_5 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 574.0
PYH3_k127_4712316_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 551.0
PYH3_k127_4712316_7 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 487.0
PYH3_k127_4712316_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 406.0
PYH3_k127_4712316_9 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 361.0
PYH3_k127_4735934_0 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 416.0
PYH3_k127_4735934_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH3_k127_4735934_2 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000006476 179.0
PYH3_k127_4736123_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 2.579e-244 763.0
PYH3_k127_4736123_1 Prolyl oligopeptidase family - - - 2.736e-220 701.0
PYH3_k127_4736123_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000001554 220.0
PYH3_k127_4736123_11 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000003412 174.0
PYH3_k127_4736123_12 - - - - 0.0000000000000000000000000000000000002675 158.0
PYH3_k127_4736123_13 - - - - 0.00000000000000000000003571 104.0
PYH3_k127_4736123_14 - - - - 0.00000000000000000000006986 108.0
PYH3_k127_4736123_15 Domain of unknown function (DUF1840) - - - 0.000000000000004712 79.0
PYH3_k127_4736123_16 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000006068 75.0
PYH3_k127_4736123_17 - - - - 0.00000000003188 70.0
PYH3_k127_4736123_2 von Willebrand factor, type A K07114 - - 8.744e-215 686.0
PYH3_k127_4736123_3 Sulfatase - - - 7.274e-213 682.0
PYH3_k127_4736123_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 581.0
PYH3_k127_4736123_5 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 465.0
PYH3_k127_4736123_6 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 270.0
PYH3_k127_4736123_7 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
PYH3_k127_4736123_8 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000007994 233.0
PYH3_k127_4736123_9 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000007131 211.0
PYH3_k127_4747620_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.172e-199 640.0
PYH3_k127_4747620_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 500.0
PYH3_k127_4747620_10 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000003611 158.0
PYH3_k127_4747620_11 similarity to GP 3192745 - - - 0.0000000000000000000000000002069 117.0
PYH3_k127_4747620_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 482.0
PYH3_k127_4747620_3 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 482.0
PYH3_k127_4747620_4 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 456.0
PYH3_k127_4747620_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 351.0
PYH3_k127_4747620_6 Major facilitator superfamily K07552,K18552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 336.0
PYH3_k127_4747620_7 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000001087 233.0
PYH3_k127_4747620_8 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000002286 237.0
PYH3_k127_4747620_9 PFAM Secreted repeat of - - - 0.00000000000000000000000000000000000000000000000002548 182.0
PYH3_k127_4817212_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.764e-228 711.0
PYH3_k127_4817212_1 ribonuclease, Rne Rng family K08301 - - 6.885e-228 716.0
PYH3_k127_4817212_10 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 299.0
PYH3_k127_4817212_11 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 297.0
PYH3_k127_4817212_12 heptosyltransferase K02843 - - 0.00000000000000000000000000000000000000000000000000000000000437 220.0
PYH3_k127_4817212_13 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000002145 210.0
PYH3_k127_4817212_14 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000001658 203.0
PYH3_k127_4817212_15 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.000000000000000000000000000000000000000000000000004151 190.0
PYH3_k127_4817212_16 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000003537 174.0
PYH3_k127_4817212_17 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000003521 172.0
PYH3_k127_4817212_18 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000009068 175.0
PYH3_k127_4817212_19 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000004165 158.0
PYH3_k127_4817212_2 Belongs to the GARS family K01945 - 6.3.4.13 1.171e-198 630.0
PYH3_k127_4817212_20 methyltransferase - - - 0.0000000000000000001011 102.0
PYH3_k127_4817212_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 550.0
PYH3_k127_4817212_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 514.0
PYH3_k127_4817212_5 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 492.0
PYH3_k127_4817212_6 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 398.0
PYH3_k127_4817212_7 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
PYH3_k127_4817212_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 326.0
PYH3_k127_4817212_9 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 310.0
PYH3_k127_4846550_0 CHASE - - - 0.00000000000000000000000000000000000000000000000000000000000000000002501 241.0
PYH3_k127_4846550_1 cyclic-guanylate-specific phosphodiesterase activity - - - 0.0000000000000001584 87.0
PYH3_k127_4846550_2 histidine kinase A domain protein - - - 0.00000000000009785 76.0
PYH3_k127_4914688_0 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 6.512e-247 771.0
PYH3_k127_4914688_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 6.434e-246 768.0
PYH3_k127_4914688_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 515.0
PYH3_k127_4914688_3 signal transduction protein containing sensor and EAL - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 325.0
PYH3_k127_4914688_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007847 241.0
PYH3_k127_4914688_5 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
PYH3_k127_4914688_6 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000000000004178 202.0
PYH3_k127_4914688_7 Formate dehydrogenase gamma subunit K00127 - - 0.00000000000000000000000000000000000000000000002405 179.0
PYH3_k127_4914688_8 esterase - - - 0.0000000000000000000000000003263 119.0
PYH3_k127_4920191_0 FAD linked oxidase domain protein - - - 0.0 2015.0
PYH3_k127_4920191_1 - - - - 0.0000000000000000000000000000000000003129 149.0
PYH3_k127_4922776_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.631e-264 819.0
PYH3_k127_4922776_1 protein related to plant photosystem II stability assembly factor - - - 6.057e-214 670.0
PYH3_k127_4922776_10 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000006557 181.0
PYH3_k127_4922776_11 Involved in biosynthesis of extracellular polysaccharides - - - 0.0000000000000000000000000000000000000000000000003447 180.0
PYH3_k127_4922776_12 ThiS family K03636 - - 0.000000000000000000000000000000001431 130.0
PYH3_k127_4922776_13 membrane K08972 - - 0.00000000000000000000000000000003343 132.0
PYH3_k127_4922776_14 - - - - 0.00004861 51.0
PYH3_k127_4922776_2 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 416.0
PYH3_k127_4922776_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 294.0
PYH3_k127_4922776_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 289.0
PYH3_k127_4922776_5 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001123 284.0
PYH3_k127_4922776_6 Glutathione S-transferase, N-terminal domain K11208 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
PYH3_k127_4922776_7 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003392 230.0
PYH3_k127_4922776_8 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000000000001009 217.0
PYH3_k127_4922776_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000473 209.0
PYH3_k127_4931833_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 440.0
PYH3_k127_4931833_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
PYH3_k127_4931833_2 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000001842 109.0
PYH3_k127_4933917_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.183e-225 718.0
PYH3_k127_4933917_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.862e-221 693.0
PYH3_k127_4933917_10 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 355.0
PYH3_k127_4933917_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 357.0
PYH3_k127_4933917_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 291.0
PYH3_k127_4933917_13 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 287.0
PYH3_k127_4933917_14 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001641 284.0
PYH3_k127_4933917_15 (FHA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH3_k127_4933917_16 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006036 257.0
PYH3_k127_4933917_17 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001416 246.0
PYH3_k127_4933917_18 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000001145 216.0
PYH3_k127_4933917_19 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000007456 211.0
PYH3_k127_4933917_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.482e-203 637.0
PYH3_k127_4933917_20 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000007284 213.0
PYH3_k127_4933917_21 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000007408 156.0
PYH3_k127_4933917_22 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000001258 145.0
PYH3_k127_4933917_23 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000003014 139.0
PYH3_k127_4933917_24 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000002147 84.0
PYH3_k127_4933917_25 Pfam Transposase - - - 0.00000000000005026 72.0
PYH3_k127_4933917_26 - - - - 0.000000000134 66.0
PYH3_k127_4933917_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 548.0
PYH3_k127_4933917_4 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 532.0
PYH3_k127_4933917_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 508.0
PYH3_k127_4933917_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 490.0
PYH3_k127_4933917_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 445.0
PYH3_k127_4933917_8 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 444.0
PYH3_k127_4933917_9 Mg2 and Co2 transporter K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 392.0
PYH3_k127_4938788_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.858e-252 802.0
PYH3_k127_4967229_0 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 478.0
PYH3_k127_4967229_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002063 261.0
PYH3_k127_4967229_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00003837 49.0
PYH3_k127_4984219_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 332.0
PYH3_k127_4984219_1 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 328.0
PYH3_k127_4984219_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000001674 151.0
PYH3_k127_4984219_3 NHL repeat - - - 0.0000000000000000000000000000000000006665 143.0
PYH3_k127_4984219_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000001731 122.0
PYH3_k127_4984219_5 DNA replication protein - - - 0.000000006635 61.0
PYH3_k127_4995188_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1037.0
PYH3_k127_4995188_1 prolyl oligopeptidase K01322 - 3.4.21.26 2.489e-219 700.0
PYH3_k127_4995188_10 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000002939 226.0
PYH3_k127_4995188_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000001431 166.0
PYH3_k127_4995188_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000001032 150.0
PYH3_k127_4995188_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 587.0
PYH3_k127_4995188_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 523.0
PYH3_k127_4995188_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 452.0
PYH3_k127_4995188_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 409.0
PYH3_k127_4995188_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 358.0
PYH3_k127_4995188_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
PYH3_k127_4995188_8 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 285.0
PYH3_k127_4995188_9 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008069 233.0
PYH3_k127_5007246_0 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000000000002914 229.0
PYH3_k127_5007246_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000001657 212.0
PYH3_k127_5007246_2 Protein of unknown function (DUF2788) - - - 0.000000000000000000000002182 105.0
PYH3_k127_5007246_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000007705 56.0
PYH3_k127_5012398_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1579.0
PYH3_k127_5012398_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1277.0
PYH3_k127_5012398_10 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 294.0
PYH3_k127_5012398_11 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
PYH3_k127_5012398_12 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
PYH3_k127_5012398_13 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004414 248.0
PYH3_k127_5012398_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000008073 214.0
PYH3_k127_5012398_15 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000002736 161.0
PYH3_k127_5012398_16 Ferredoxin K05337 - - 0.0000000000000000000000000000000004418 133.0
PYH3_k127_5012398_17 Protein conserved in bacteria - - - 0.00000000000000000000000000000006431 132.0
PYH3_k127_5012398_18 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000001647 132.0
PYH3_k127_5012398_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000005248 113.0
PYH3_k127_5012398_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1016.0
PYH3_k127_5012398_20 DNA integration - - - 0.00003834 49.0
PYH3_k127_5012398_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.613e-228 710.0
PYH3_k127_5012398_4 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 587.0
PYH3_k127_5012398_5 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 387.0
PYH3_k127_5012398_6 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
PYH3_k127_5012398_7 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
PYH3_k127_5012398_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 325.0
PYH3_k127_5012398_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 299.0
PYH3_k127_5025618_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 4.443e-312 967.0
PYH3_k127_5025618_1 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000003544 153.0
PYH3_k127_5025618_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000009965 140.0
PYH3_k127_5025618_3 Cytochrome c K08738 - - 0.0000000000000000000000000000004045 124.0
PYH3_k127_5025618_4 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000001557 94.0
PYH3_k127_5025618_5 receptor K16087,K16089 - - 0.0000000001381 62.0
PYH3_k127_5031410_0 B12 binding domain K00548 - 2.1.1.13 0.0 1835.0
PYH3_k127_5031410_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 385.0
PYH3_k127_5031410_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000005188 165.0
PYH3_k127_5031410_3 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000002323 161.0
PYH3_k127_5031410_4 - - - - 0.000000000000000000000000000000318 136.0
PYH3_k127_5031410_5 Protein of unknown function (DUF3567) - - - 0.000000000000000000000002859 104.0
PYH3_k127_5031410_6 Homeodomain-like domain - - - 0.00008775 46.0
PYH3_k127_5041966_0 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
PYH3_k127_5041966_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000006852 144.0
PYH3_k127_5041966_2 PFAM peptidase - - - 0.0000000000005498 69.0
PYH3_k127_5067274_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2365.0
PYH3_k127_5067274_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2305.0
PYH3_k127_5067274_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000005117 154.0
PYH3_k127_5067274_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000003026 87.0
PYH3_k127_5067274_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000006926 77.0
PYH3_k127_5067274_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1234.0
PYH3_k127_5067274_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 338.0
PYH3_k127_5067274_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 302.0
PYH3_k127_5067274_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001732 270.0
PYH3_k127_5067274_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001118 267.0
PYH3_k127_5067274_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 246.0
PYH3_k127_5067274_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000002575 227.0
PYH3_k127_5067274_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000033 189.0
PYH3_k127_5068009_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2522.0
PYH3_k127_5068009_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 1.056e-288 907.0
PYH3_k127_5068009_10 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 538.0
PYH3_k127_5068009_11 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 517.0
PYH3_k127_5068009_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 464.0
PYH3_k127_5068009_13 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0003674,GO:0003824,GO:0003920,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016491,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030097,GO:0030099,GO:0030154,GO:0030224,GO:0032501,GO:0032502,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046038,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0048513,GO:0048534,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1903131 1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 464.0
PYH3_k127_5068009_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 460.0
PYH3_k127_5068009_15 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 457.0
PYH3_k127_5068009_16 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 456.0
PYH3_k127_5068009_17 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 420.0
PYH3_k127_5068009_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 430.0
PYH3_k127_5068009_19 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 414.0
PYH3_k127_5068009_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.175e-250 780.0
PYH3_k127_5068009_20 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 414.0
PYH3_k127_5068009_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 405.0
PYH3_k127_5068009_22 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 403.0
PYH3_k127_5068009_23 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 385.0
PYH3_k127_5068009_24 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 378.0
PYH3_k127_5068009_25 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 367.0
PYH3_k127_5068009_26 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 366.0
PYH3_k127_5068009_27 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 366.0
PYH3_k127_5068009_28 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 365.0
PYH3_k127_5068009_29 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 348.0
PYH3_k127_5068009_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.657e-237 738.0
PYH3_k127_5068009_30 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
PYH3_k127_5068009_31 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 331.0
PYH3_k127_5068009_32 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 330.0
PYH3_k127_5068009_33 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 322.0
PYH3_k127_5068009_34 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 321.0
PYH3_k127_5068009_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 317.0
PYH3_k127_5068009_36 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 304.0
PYH3_k127_5068009_37 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000156 280.0
PYH3_k127_5068009_38 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 280.0
PYH3_k127_5068009_39 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002225 271.0
PYH3_k127_5068009_4 Secretin and TonB N terminus short domain K02666 - - 1.157e-229 734.0
PYH3_k127_5068009_40 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007217 274.0
PYH3_k127_5068009_41 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002003 260.0
PYH3_k127_5068009_42 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
PYH3_k127_5068009_43 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007562 257.0
PYH3_k127_5068009_44 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000368 247.0
PYH3_k127_5068009_45 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000001538 258.0
PYH3_k127_5068009_46 PFAM cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
PYH3_k127_5068009_47 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000001518 243.0
PYH3_k127_5068009_48 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000001656 228.0
PYH3_k127_5068009_49 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000268 228.0
PYH3_k127_5068009_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.362e-208 657.0
PYH3_k127_5068009_50 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000001045 226.0
PYH3_k127_5068009_51 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000002139 222.0
PYH3_k127_5068009_52 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000112 224.0
PYH3_k127_5068009_53 PFAM Ig domain protein, group 1 domain protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000001267 241.0
PYH3_k127_5068009_54 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000003316 221.0
PYH3_k127_5068009_55 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000001308 211.0
PYH3_k127_5068009_56 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000002801 207.0
PYH3_k127_5068009_57 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000001056 201.0
PYH3_k127_5068009_58 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000001687 196.0
PYH3_k127_5068009_59 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000000000345 192.0
PYH3_k127_5068009_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 606.0
PYH3_k127_5068009_60 Psort location Extracellular, score K07126 - - 0.00000000000000000000000000000000000000000000000000002909 196.0
PYH3_k127_5068009_61 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000002925 186.0
PYH3_k127_5068009_62 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000003478 194.0
PYH3_k127_5068009_63 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000007649 190.0
PYH3_k127_5068009_64 Cupin domain - - - 0.000000000000000000000000000000000000000000000004689 179.0
PYH3_k127_5068009_65 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000004304 175.0
PYH3_k127_5068009_66 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000113 171.0
PYH3_k127_5068009_67 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001699 165.0
PYH3_k127_5068009_68 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000002991 166.0
PYH3_k127_5068009_69 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000003717 171.0
PYH3_k127_5068009_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 570.0
PYH3_k127_5068009_70 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000002835 165.0
PYH3_k127_5068009_71 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000225 160.0
PYH3_k127_5068009_72 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003194 150.0
PYH3_k127_5068009_73 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000008704 147.0
PYH3_k127_5068009_74 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000001009 149.0
PYH3_k127_5068009_75 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000001084 149.0
PYH3_k127_5068009_76 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000354 145.0
PYH3_k127_5068009_77 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000005642 147.0
PYH3_k127_5068009_78 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000002804 144.0
PYH3_k127_5068009_79 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000000000001959 137.0
PYH3_k127_5068009_8 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 547.0
PYH3_k127_5068009_80 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000000002734 140.0
PYH3_k127_5068009_81 tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000003709 134.0
PYH3_k127_5068009_82 Redoxin domain protein - - - 0.00000000000000000000000000000000473 140.0
PYH3_k127_5068009_83 RNA-binding protein S4 K04762 - - 0.0000000000000000000000000000000629 130.0
PYH3_k127_5068009_84 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000001366 129.0
PYH3_k127_5068009_85 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000009948 120.0
PYH3_k127_5068009_86 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000003755 104.0
PYH3_k127_5068009_87 Ribosomal protein L30 K02907 - - 0.0000000000000000003518 93.0
PYH3_k127_5068009_88 Ribosomal L29 protein K02904 - - 0.00000000000000009356 86.0
PYH3_k127_5068009_89 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000006926 77.0
PYH3_k127_5068009_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 539.0
PYH3_k127_5068009_90 Ribosomal protein L36 K02919 - - 0.000000000000008782 74.0
PYH3_k127_5068009_91 STAS domain K07122 - - 0.0000000000001284 74.0
PYH3_k127_5100585_0 PFAM transposase IS66 - - - 9.392e-248 773.0
PYH3_k127_5100585_1 IS66 Orf2 like protein - - - 0.00000000000000000000000000000000000000000000000000000000003541 207.0
PYH3_k127_5100585_2 Transposase K07483 - - 0.000000000003756 71.0
PYH3_k127_5120254_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000002336 191.0
PYH3_k127_5120254_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000002765 158.0
PYH3_k127_5120254_2 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.00000000004252 75.0
PYH3_k127_5151751_0 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 359.0
PYH3_k127_5151751_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000004846 235.0
PYH3_k127_5151751_2 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000005059 151.0
PYH3_k127_5151751_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000004901 114.0
PYH3_k127_5151751_4 Prokaryotic cytochrome b561 - - - 0.00000000000000000000271 98.0
PYH3_k127_5151751_5 lipolytic protein G-D-S-L family - - - 0.000000000000001901 89.0
PYH3_k127_5151751_6 LTXXQ motif family protein - - - 0.0002695 50.0
PYH3_k127_5165117_0 ABC transporter transmembrane region K06147 - - 3.191e-263 831.0
PYH3_k127_5165117_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 584.0
PYH3_k127_5165117_10 - - - - 0.00000000000000000000000000000000000000009384 160.0
PYH3_k127_5165117_11 - - - - 0.00000000000000000000000000001502 127.0
PYH3_k127_5165117_12 Fumarase C C-terminus K01744 - 4.3.1.1 0.00001574 49.0
PYH3_k127_5165117_2 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 584.0
PYH3_k127_5165117_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 547.0
PYH3_k127_5165117_4 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 547.0
PYH3_k127_5165117_5 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 448.0
PYH3_k127_5165117_6 acid transport system permease K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 384.0
PYH3_k127_5165117_7 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 353.0
PYH3_k127_5165117_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 279.0
PYH3_k127_5165117_9 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000008614 198.0
PYH3_k127_519115_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1545.0
PYH3_k127_519115_1 L-serine dehydratase K01752 - 4.3.1.17 7.981e-228 715.0
PYH3_k127_519115_10 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 419.0
PYH3_k127_519115_11 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
PYH3_k127_519115_12 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
PYH3_k127_519115_13 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 336.0
PYH3_k127_519115_14 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 314.0
PYH3_k127_519115_15 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000001615 229.0
PYH3_k127_519115_16 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000001365 189.0
PYH3_k127_519115_17 amidase activity - - - 0.000000000000000000000000000000000000000000000000001701 186.0
PYH3_k127_519115_19 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000001949 134.0
PYH3_k127_519115_2 PERMEase K06901 - - 1.661e-225 710.0
PYH3_k127_519115_20 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000006961 134.0
PYH3_k127_519115_21 - - - - 0.00000000000000000000000000003511 122.0
PYH3_k127_519115_22 peptidoglycan-binding protein, lysm - - - 0.0000000000000000006789 88.0
PYH3_k127_519115_23 Protein of unknown function (DUF2877) - - - 0.00000000000000002306 93.0
PYH3_k127_519115_3 ABC-type dipeptide transport system periplasmic component K02035 - - 1.265e-220 694.0
PYH3_k127_519115_4 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 617.0
PYH3_k127_519115_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 502.0
PYH3_k127_519115_6 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 503.0
PYH3_k127_519115_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 450.0
PYH3_k127_519115_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 424.0
PYH3_k127_519115_9 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 411.0
PYH3_k127_5203533_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 4.718e-310 962.0
PYH3_k127_5203533_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.041e-280 871.0
PYH3_k127_5203533_10 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
PYH3_k127_5203533_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
PYH3_k127_5203533_12 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
PYH3_k127_5203533_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000005754 159.0
PYH3_k127_5203533_14 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000007452 143.0
PYH3_k127_5203533_15 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000005561 127.0
PYH3_k127_5203533_16 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000000000000000005645 97.0
PYH3_k127_5203533_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.276e-245 766.0
PYH3_k127_5203533_3 Methionine gamma-lyase K01761 - 4.4.1.11 2.179e-209 660.0
PYH3_k127_5203533_4 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 570.0
PYH3_k127_5203533_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 575.0
PYH3_k127_5203533_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 549.0
PYH3_k127_5203533_7 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 469.0
PYH3_k127_5203533_8 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 353.0
PYH3_k127_5203533_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 313.0
PYH3_k127_5213501_0 Flavin containing amine oxidoreductase K06955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 475.0
PYH3_k127_5213501_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 303.0
PYH3_k127_5213501_10 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.0000000000001511 74.0
PYH3_k127_5213501_11 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.0000000000002668 72.0
PYH3_k127_5213501_13 Alpha/beta hydrolase family - - - 0.0000000001016 66.0
PYH3_k127_5213501_2 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005504 265.0
PYH3_k127_5213501_3 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003416 243.0
PYH3_k127_5213501_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000002259 220.0
PYH3_k127_5213501_5 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000008069 216.0
PYH3_k127_5213501_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000008813 176.0
PYH3_k127_5213501_7 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000000000000000003388 128.0
PYH3_k127_5213501_8 - - - - 0.00000000000000000007748 95.0
PYH3_k127_5213501_9 - - - - 0.000000000000000003588 85.0
PYH3_k127_5223836_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 427.0
PYH3_k127_5223836_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.00000000000000000000000000000000000000000000000000000001751 197.0
PYH3_k127_5223836_2 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.00000000000000000000000000000000000000001576 159.0
PYH3_k127_5236191_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 387.0
PYH3_k127_5236191_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 366.0
PYH3_k127_5236191_2 - - - - 0.000000000009785 66.0
PYH3_k127_5236191_3 - - - - 0.000002345 56.0
PYH3_k127_5248302_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0 1003.0
PYH3_k127_5248302_1 peptidase dimerisation domain protein - - - 2.053e-209 657.0
PYH3_k127_5248302_2 deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 590.0
PYH3_k127_5248302_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 541.0
PYH3_k127_5248302_4 Nucleoside-binding outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000001195 226.0
PYH3_k127_5248302_5 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000005593 185.0
PYH3_k127_5248302_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000008147 181.0
PYH3_k127_5248302_7 Family of unknown function (DUF5329) - - - 0.000000000000000000000000000000000002478 142.0
PYH3_k127_5248302_8 s cog2930 - - - 0.000000000000001004 77.0
PYH3_k127_5298000_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.064e-265 822.0
PYH3_k127_5298000_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 543.0
PYH3_k127_5298000_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000003071 188.0
PYH3_k127_5298000_3 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000464 136.0
PYH3_k127_5298000_4 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000002342 107.0
PYH3_k127_5298000_5 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000007112 97.0
PYH3_k127_5298000_6 HEPN domain - - - 0.000000000000001575 83.0
PYH3_k127_5298000_7 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000001654 67.0
PYH3_k127_5361387_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
PYH3_k127_5361387_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 489.0
PYH3_k127_5361387_10 Protein of unknown function (DUF1289) K06938 - - 0.000000000000001108 79.0
PYH3_k127_5361387_11 - - - - 0.00000000003698 74.0
PYH3_k127_5361387_12 pyridoxamine 5-phosphate - - - 0.00002997 47.0
PYH3_k127_5361387_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 308.0
PYH3_k127_5361387_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000009836 224.0
PYH3_k127_5361387_4 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
PYH3_k127_5361387_6 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000008823 190.0
PYH3_k127_5361387_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000004257 174.0
PYH3_k127_5361387_8 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000007938 150.0
PYH3_k127_5361387_9 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000008289 111.0
PYH3_k127_5376521_0 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 399.0
PYH3_k127_5376521_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000242 194.0
PYH3_k127_5376521_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000001011 94.0
PYH3_k127_5376521_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000001155 69.0
PYH3_k127_5397064_0 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 592.0
PYH3_k127_5397064_1 Pfam:DUF989 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 573.0
PYH3_k127_5397064_2 Basic membrane lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000001952 223.0
PYH3_k127_5397064_3 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000004976 175.0
PYH3_k127_5397064_4 - - - - 0.000000000000000000000001781 110.0
PYH3_k127_5397064_5 peptidyl-tyrosine sulfation - - - 0.0002336 46.0
PYH3_k127_5403745_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 3.316e-266 844.0
PYH3_k127_5403745_1 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 582.0
PYH3_k127_5403745_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 458.0
PYH3_k127_5403745_3 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 367.0
PYH3_k127_5403745_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000001684 217.0
PYH3_k127_5403745_5 PFAM TonB-dependent receptor, beta-barrel K02014 - - 0.0004026 45.0
PYH3_k127_5437112_0 Damage-inducible protein DinB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001494 249.0
PYH3_k127_5437112_1 ORF6N domain - - - 0.0000000000000000000000000000003863 124.0
PYH3_k127_5437112_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.0000000000000005546 86.0
PYH3_k127_5445394_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1148.0
PYH3_k127_5445394_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 624.0
PYH3_k127_5445394_10 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000000000000000005218 214.0
PYH3_k127_5445394_11 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000005839 204.0
PYH3_k127_5445394_12 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000003929 198.0
PYH3_k127_5445394_13 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000005542 158.0
PYH3_k127_5445394_14 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000003862 150.0
PYH3_k127_5445394_2 Heavy-metal-associated domain K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 539.0
PYH3_k127_5445394_3 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 383.0
PYH3_k127_5445394_4 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 374.0
PYH3_k127_5445394_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 365.0
PYH3_k127_5445394_6 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 364.0
PYH3_k127_5445394_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 335.0
PYH3_k127_5445394_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000002145 250.0
PYH3_k127_5445394_9 PFAM Fructosamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007733 254.0
PYH3_k127_5447299_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1547.0
PYH3_k127_5447299_1 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 1.965e-300 931.0
PYH3_k127_5447299_10 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002364 279.0
PYH3_k127_5447299_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000001191 228.0
PYH3_k127_5447299_12 Complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
PYH3_k127_5447299_13 LysM domain K08086 - - 0.00000000000000000000000000000000000000000000000000007527 206.0
PYH3_k127_5447299_14 Sporulation related domain K03749 - - 0.000000000000000000000000002492 120.0
PYH3_k127_5447299_15 Ion channel - - - 0.0000000000000000000000001319 109.0
PYH3_k127_5447299_16 Colicin V production protein K03558 - - 0.0000000000000000000000009873 109.0
PYH3_k127_5447299_17 Staphylococcal nuclease homologues - - - 0.000000000000000000142 96.0
PYH3_k127_5447299_18 helix_turn_helix, Lux Regulon - - - 0.0000000000000009663 79.0
PYH3_k127_5447299_19 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000005152 77.0
PYH3_k127_5447299_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.623e-250 781.0
PYH3_k127_5447299_20 Alpha/beta hydrolase family - - - 0.00000000001318 67.0
PYH3_k127_5447299_21 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000888 60.0
PYH3_k127_5447299_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 6.72e-226 704.0
PYH3_k127_5447299_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 536.0
PYH3_k127_5447299_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 510.0
PYH3_k127_5447299_6 Periplasmic binding protein-like domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 502.0
PYH3_k127_5447299_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 478.0
PYH3_k127_5447299_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 364.0
PYH3_k127_5447299_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 313.0
PYH3_k127_5449704_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1659.0
PYH3_k127_5449704_1 NADPH-dependent glutamate synthase beta - - - 1.302e-310 962.0
PYH3_k127_5449704_10 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 448.0
PYH3_k127_5449704_11 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 442.0
PYH3_k127_5449704_12 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 407.0
PYH3_k127_5449704_13 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 395.0
PYH3_k127_5449704_14 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 355.0
PYH3_k127_5449704_15 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 345.0
PYH3_k127_5449704_16 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 340.0
PYH3_k127_5449704_17 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003231 258.0
PYH3_k127_5449704_18 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000002359 250.0
PYH3_k127_5449704_19 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000262 198.0
PYH3_k127_5449704_2 Fe-S oxidoreductase K21834 - - 7.313e-287 885.0
PYH3_k127_5449704_20 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000165 197.0
PYH3_k127_5449704_21 Belongs to the DsrF TusC family K07236 - - 0.0000000000000000000000000000000000000000000000003879 177.0
PYH3_k127_5449704_22 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000005283 162.0
PYH3_k127_5449704_23 Cas6 Crispr - - - 0.00000000000000000000000000000000000000005033 160.0
PYH3_k127_5449704_24 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000003132 156.0
PYH3_k127_5449704_25 - - - - 0.0000000000000000000000000000000000000006027 160.0
PYH3_k127_5449704_26 DsrC like protein K11179 - - 0.000000000000000000000000000000000000007102 153.0
PYH3_k127_5449704_27 DsrH like protein K07237 - - 0.0000000000000000000000000000000001294 134.0
PYH3_k127_5449704_28 - - - - 0.000000000000000000000001189 109.0
PYH3_k127_5449704_29 PFAM CBS domain containing protein - - - 0.00000000000000000000009755 104.0
PYH3_k127_5449704_3 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.763e-248 770.0
PYH3_k127_5449704_30 - - - - 0.0000000000000000000005424 98.0
PYH3_k127_5449704_31 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000006278 91.0
PYH3_k127_5449704_32 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000004665 79.0
PYH3_k127_5449704_4 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 9.238e-231 732.0
PYH3_k127_5449704_5 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.554e-221 696.0
PYH3_k127_5449704_6 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 7.317e-213 664.0
PYH3_k127_5449704_7 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 588.0
PYH3_k127_5449704_8 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 480.0
PYH3_k127_5449704_9 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 478.0
PYH3_k127_5459315_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.529e-198 639.0
PYH3_k127_5459315_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 511.0
PYH3_k127_5459315_10 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.000000000000001885 76.0
PYH3_k127_5459315_11 Type II transport protein GspH K08084 - - 0.000000000000009681 82.0
PYH3_k127_5459315_12 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000002118 80.0
PYH3_k127_5459315_13 Pilus assembly protein K08084 - - 0.00000000000006637 79.0
PYH3_k127_5459315_2 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 537.0
PYH3_k127_5459315_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006668 253.0
PYH3_k127_5459315_4 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000957 198.0
PYH3_k127_5459315_5 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000001295 177.0
PYH3_k127_5459315_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000009578 162.0
PYH3_k127_5459315_7 pilus modification protein PilV K02671 - - 0.0000000000000000003228 94.0
PYH3_k127_5459315_8 TonB family K03832 - - 0.000000000000000006597 91.0
PYH3_k127_5459315_9 PilX N-terminal K02673 - - 0.00000000000000001158 93.0
PYH3_k127_5475051_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1275.0
PYH3_k127_5475051_1 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1016.0
PYH3_k127_5475051_10 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 299.0
PYH3_k127_5475051_11 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000001493 214.0
PYH3_k127_5475051_12 HIUase/Transthyretin family K07127 - 3.5.2.17 0.0000000000000000000000000000000001048 136.0
PYH3_k127_5475051_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000001372 123.0
PYH3_k127_5475051_14 phosphocarrier protein HPr K11189 - - 0.0000000000000000005672 90.0
PYH3_k127_5475051_15 Mechanosensitive ion channel - - - 0.000001625 53.0
PYH3_k127_5475051_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 6.977e-224 704.0
PYH3_k127_5475051_3 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 615.0
PYH3_k127_5475051_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 477.0
PYH3_k127_5475051_5 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 452.0
PYH3_k127_5475051_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 389.0
PYH3_k127_5475051_7 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 385.0
PYH3_k127_5475051_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 381.0
PYH3_k127_5475051_9 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
PYH3_k127_5515245_0 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 592.0
PYH3_k127_5515245_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 445.0
PYH3_k127_5515245_2 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002674 284.0
PYH3_k127_5515245_3 Type II secretion system protein B K02451 - - 0.0000000006005 64.0
PYH3_k127_5515245_4 Ureidoglycolate lyase - - - 0.00002409 48.0
PYH3_k127_5553722_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.09e-218 693.0
PYH3_k127_5553722_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 531.0
PYH3_k127_5553722_10 PFAM beta-lactamase domain protein - - - 0.0004509 46.0
PYH3_k127_5553722_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 520.0
PYH3_k127_5553722_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 448.0
PYH3_k127_5553722_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 276.0
PYH3_k127_5553722_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000003484 256.0
PYH3_k127_5553722_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
PYH3_k127_5553722_7 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000003838 174.0
PYH3_k127_5553722_8 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000000000000000001049 141.0
PYH3_k127_5553722_9 protein domain associated with - - - 0.0000000000000000000000000000000000397 146.0
PYH3_k127_5573361_0 Beta/gamma crystallins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 334.0
PYH3_k127_5573361_1 cell septum assembly - - - 0.00000000000000005309 83.0
PYH3_k127_5573361_2 Protein kinase domain K08282 - 2.7.11.1 0.00000000000009586 71.0
PYH3_k127_5575862_0 PFAM AMP-dependent synthetase and ligase K00666,K01897,K18661 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 372.0
PYH3_k127_5575862_1 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 305.0
PYH3_k127_5575862_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 293.0
PYH3_k127_5575862_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000009823 237.0
PYH3_k127_5596470_0 Adenylosuccinate lyase C-terminal K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 597.0
PYH3_k127_5596470_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 458.0
PYH3_k127_5596470_10 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000004574 61.0
PYH3_k127_5596470_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 443.0
PYH3_k127_5596470_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 403.0
PYH3_k127_5596470_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
PYH3_k127_5596470_5 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 295.0
PYH3_k127_5596470_6 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 294.0
PYH3_k127_5596470_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000006637 252.0
PYH3_k127_5596470_8 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000000000005096 159.0
PYH3_k127_5596470_9 PFAM cytochrome c - - - 0.0000000003583 70.0
PYH3_k127_5613305_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 595.0
PYH3_k127_5613305_1 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 595.0
PYH3_k127_5613305_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000001285 193.0
PYH3_k127_5613305_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000008089 104.0
PYH3_k127_5613305_4 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000001777 98.0
PYH3_k127_5672524_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.492e-310 960.0
PYH3_k127_5672524_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.877e-253 786.0
PYH3_k127_5672524_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 574.0
PYH3_k127_5672524_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
PYH3_k127_5672524_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 335.0
PYH3_k127_5672524_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009591 261.0
PYH3_k127_5672524_6 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000001125 223.0
PYH3_k127_5672524_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000001592 184.0
PYH3_k127_5672524_8 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000002034 185.0
PYH3_k127_5672524_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000001904 81.0
PYH3_k127_5728938_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1394.0
PYH3_k127_5728938_1 Large family of predicted nucleotide-binding domains K07175 - - 9.62e-243 760.0
PYH3_k127_5728938_10 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 426.0
PYH3_k127_5728938_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 314.0
PYH3_k127_5728938_12 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001832 284.0
PYH3_k127_5728938_13 PFAM Fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
PYH3_k127_5728938_14 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003166 270.0
PYH3_k127_5728938_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001208 241.0
PYH3_k127_5728938_16 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
PYH3_k127_5728938_17 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000002303 211.0
PYH3_k127_5728938_18 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000006176 205.0
PYH3_k127_5728938_19 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000005087 192.0
PYH3_k127_5728938_2 Aminotransferase K14261 - - 6.467e-227 707.0
PYH3_k127_5728938_20 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000007755 186.0
PYH3_k127_5728938_21 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000000007853 184.0
PYH3_k127_5728938_22 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000004158 150.0
PYH3_k127_5728938_23 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000006895 147.0
PYH3_k127_5728938_24 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000008714 149.0
PYH3_k127_5728938_25 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000007138 89.0
PYH3_k127_5728938_26 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000007473 98.0
PYH3_k127_5728938_27 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000003055 90.0
PYH3_k127_5728938_28 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000008294 65.0
PYH3_k127_5728938_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.642e-218 685.0
PYH3_k127_5728938_4 homoserine dehydrogenase K00003 - 1.1.1.3 2.309e-199 629.0
PYH3_k127_5728938_5 Threonine synthase K01733 - 4.2.3.1 6.141e-194 619.0
PYH3_k127_5728938_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 519.0
PYH3_k127_5728938_7 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 494.0
PYH3_k127_5728938_8 JmjC domain, hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 477.0
PYH3_k127_5728938_9 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 504.0
PYH3_k127_5735561_0 PFAM carboxyl transferase K01615 - 4.1.1.70 1.508e-267 829.0
PYH3_k127_5735561_1 Mrr N-terminal domain K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 388.0
PYH3_k127_5735561_2 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000006407 240.0
PYH3_k127_5735561_3 ORF6N domain - - - 0.000000000000000000000000000000000000000000000002373 179.0
PYH3_k127_5735561_4 Pfam:DUF1446 - - - 0.0000000000000000000000000000000000000000006992 163.0
PYH3_k127_5735561_5 Domain of unknown function (DUF4387) - - - 0.0000000000000000000000000000000000000001801 152.0
PYH3_k127_5735561_6 - - - - 0.00000000000000000000000000000000001939 137.0
PYH3_k127_5735561_7 PIN domain K07063 - - 0.0000000000000000000000125 108.0
PYH3_k127_5735561_8 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000001603 80.0
PYH3_k127_5761529_0 Cupin domain - - - 0.000000000000000000001839 96.0
PYH3_k127_5761876_0 Histidine kinase - - - 0.00000000000000000000000000000000005852 148.0
PYH3_k127_5761876_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00006289 46.0
PYH3_k127_5765038_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 475.0
PYH3_k127_5765038_1 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 302.0
PYH3_k127_5783555_0 oxidoreductase activity - - - 0.0 1079.0
PYH3_k127_5783555_1 Belongs to the malate synthase family K01638 - 2.3.3.9 4.484e-277 859.0
PYH3_k127_5783555_10 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 378.0
PYH3_k127_5783555_11 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 312.0
PYH3_k127_5783555_12 Di-haem cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000003124 240.0
PYH3_k127_5783555_13 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000006518 234.0
PYH3_k127_5783555_14 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000422 214.0
PYH3_k127_5783555_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000002347 92.0
PYH3_k127_5783555_16 to GCN5-related N-acetyltransferase of Proteobacteria UniRef RepID Q46ZY6_RALEJ K03790 - 2.3.1.128 0.00000000000000005939 89.0
PYH3_k127_5783555_17 - - - - 0.00000000002781 64.0
PYH3_k127_5783555_18 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000001093 59.0
PYH3_k127_5783555_2 Isocitrate lyase K01637 - 4.1.3.1 3.16e-250 779.0
PYH3_k127_5783555_3 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 576.0
PYH3_k127_5783555_4 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 571.0
PYH3_k127_5783555_5 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 522.0
PYH3_k127_5783555_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 525.0
PYH3_k127_5783555_7 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 522.0
PYH3_k127_5783555_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 454.0
PYH3_k127_5783555_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 419.0
PYH3_k127_5785816_0 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 1.675e-241 757.0
PYH3_k127_5785816_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 526.0
PYH3_k127_5785816_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 432.0
PYH3_k127_5785816_3 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 408.0
PYH3_k127_5785816_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
PYH3_k127_5785816_5 - - - - 0.000000000000000000000000008933 115.0
PYH3_k127_5798657_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1312.0
PYH3_k127_5798657_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1264.0
PYH3_k127_5798657_10 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.021e-202 658.0
PYH3_k127_5798657_11 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 583.0
PYH3_k127_5798657_12 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 553.0
PYH3_k127_5798657_13 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 535.0
PYH3_k127_5798657_14 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 540.0
PYH3_k127_5798657_15 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 522.0
PYH3_k127_5798657_16 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 514.0
PYH3_k127_5798657_17 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 501.0
PYH3_k127_5798657_18 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 493.0
PYH3_k127_5798657_19 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 487.0
PYH3_k127_5798657_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1013.0
PYH3_k127_5798657_20 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 482.0
PYH3_k127_5798657_21 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 452.0
PYH3_k127_5798657_22 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 416.0
PYH3_k127_5798657_23 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 398.0
PYH3_k127_5798657_24 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 395.0
PYH3_k127_5798657_25 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 365.0
PYH3_k127_5798657_26 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 359.0
PYH3_k127_5798657_27 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 339.0
PYH3_k127_5798657_28 mechanosensitive K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 352.0
PYH3_k127_5798657_29 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 329.0
PYH3_k127_5798657_3 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 9.542e-297 937.0
PYH3_k127_5798657_30 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 315.0
PYH3_k127_5798657_31 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 310.0
PYH3_k127_5798657_32 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 297.0
PYH3_k127_5798657_33 Serine hydrolase (FSH1) K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 287.0
PYH3_k127_5798657_34 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 284.0
PYH3_k127_5798657_35 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
PYH3_k127_5798657_36 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004313 263.0
PYH3_k127_5798657_37 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007769 267.0
PYH3_k127_5798657_38 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002525 254.0
PYH3_k127_5798657_39 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000001006 237.0
PYH3_k127_5798657_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 7.273e-268 843.0
PYH3_k127_5798657_40 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000002927 235.0
PYH3_k127_5798657_41 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001198 241.0
PYH3_k127_5798657_42 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000003586 237.0
PYH3_k127_5798657_43 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000002947 228.0
PYH3_k127_5798657_44 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
PYH3_k127_5798657_45 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000002253 224.0
PYH3_k127_5798657_46 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000002395 210.0
PYH3_k127_5798657_47 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000009107 203.0
PYH3_k127_5798657_48 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000008401 214.0
PYH3_k127_5798657_49 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000004243 184.0
PYH3_k127_5798657_5 TRAP dicarboxylate transporter, DctM subunit K03299 - - 2.121e-254 796.0
PYH3_k127_5798657_50 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000001824 184.0
PYH3_k127_5798657_51 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000001993 179.0
PYH3_k127_5798657_52 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000005041 193.0
PYH3_k127_5798657_53 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001124 172.0
PYH3_k127_5798657_54 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000007274 168.0
PYH3_k127_5798657_55 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000001525 160.0
PYH3_k127_5798657_56 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000004473 161.0
PYH3_k127_5798657_57 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000664 159.0
PYH3_k127_5798657_58 biopolymer transport K03559 - - 0.00000000000000000000000000000000000000009141 154.0
PYH3_k127_5798657_59 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000007597 144.0
PYH3_k127_5798657_6 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 9.656e-236 733.0
PYH3_k127_5798657_60 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000001846 143.0
PYH3_k127_5798657_61 Cold shock protein K03704 - - 0.0000000000000000000000000000000003239 134.0
PYH3_k127_5798657_62 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000005275 127.0
PYH3_k127_5798657_63 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000953 101.0
PYH3_k127_5798657_64 Trm112p-like protein K09791 - - 0.0000000000000000000001695 98.0
PYH3_k127_5798657_65 Cytochrome c, class I - - - 0.000000000000000000001975 100.0
PYH3_k127_5798657_7 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.734e-225 703.0
PYH3_k127_5798657_8 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.26e-214 681.0
PYH3_k127_5798657_9 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.534e-202 637.0
PYH3_k127_588278_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 2.528e-251 780.0
PYH3_k127_588278_1 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 1.435e-204 642.0
PYH3_k127_588278_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 454.0
PYH3_k127_588278_3 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001512 279.0
PYH3_k127_588278_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000112 177.0
PYH3_k127_588278_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000001427 116.0
PYH3_k127_588278_6 Succinylglutamate desuccinylase - - - 0.000000000008379 72.0
PYH3_k127_589240_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1323.0
PYH3_k127_589240_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 606.0
PYH3_k127_589240_10 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 289.0
PYH3_k127_589240_11 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
PYH3_k127_589240_12 PFAM pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
PYH3_k127_589240_13 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000004086 231.0
PYH3_k127_589240_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
PYH3_k127_589240_15 Glyoxalase bleomycin resistance - - - 0.00000000000000000000000000000000000000000000000000004121 189.0
PYH3_k127_589240_16 Protein of unknown function (DUF1059) - - - 0.000000000000000000000000249 108.0
PYH3_k127_589240_17 - - - - 0.000000003351 58.0
PYH3_k127_589240_18 - - - - 0.00000008929 53.0
PYH3_k127_589240_19 - - - - 0.0000026 52.0
PYH3_k127_589240_2 amp-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 511.0
PYH3_k127_589240_3 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 385.0
PYH3_k127_589240_4 ATPases associated with a variety of cellular activities K10025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 376.0
PYH3_k127_589240_5 Ligated ion channel L-glutamate- and glycine-binding site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 329.0
PYH3_k127_589240_6 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 335.0
PYH3_k127_589240_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
PYH3_k127_589240_8 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 300.0
PYH3_k127_589240_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 297.0
PYH3_k127_5945534_0 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
PYH3_k127_5945534_1 PFAM Bacterial transcriptional activator domain - - - 0.000000000000000000000000002071 121.0
PYH3_k127_5973694_0 MMPL family K07003 - - 0.0 1064.0
PYH3_k127_5973694_1 Protein of unknown function (DUF1302) - - - 5.995e-216 681.0
PYH3_k127_5973694_2 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006025 240.0
PYH3_k127_5973752_0 MMPL family K07003 - - 0.0 1067.0
PYH3_k127_5973752_1 Protein of unknown function (DUF1302) - - - 8.21e-216 681.0
PYH3_k127_5973752_2 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001219 242.0
PYH3_k127_5986456_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 3.655e-244 763.0
PYH3_k127_5986456_1 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 3.589e-224 707.0
PYH3_k127_5986456_10 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 370.0
PYH3_k127_5986456_11 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 378.0
PYH3_k127_5986456_12 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 373.0
PYH3_k127_5986456_13 Type ii and iii secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
PYH3_k127_5986456_14 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
PYH3_k127_5986456_15 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000001086 214.0
PYH3_k127_5986456_16 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08319 - 1.1.1.411 0.000000000000000000005732 100.0
PYH3_k127_5986456_18 - - - - 0.000000000000001856 82.0
PYH3_k127_5986456_19 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.00000000005807 70.0
PYH3_k127_5986456_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 569.0
PYH3_k127_5986456_21 - - - - 0.000006165 53.0
PYH3_k127_5986456_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 528.0
PYH3_k127_5986456_4 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 522.0
PYH3_k127_5986456_5 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 496.0
PYH3_k127_5986456_6 ATPases associated with a variety of cellular activities K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 477.0
PYH3_k127_5986456_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 453.0
PYH3_k127_5986456_8 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 416.0
PYH3_k127_5986456_9 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 411.0
PYH3_k127_6001749_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 572.0
PYH3_k127_6001749_1 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000007058 209.0
PYH3_k127_6001749_2 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000006744 100.0
PYH3_k127_6001749_3 Acetyl-CoA carboxylase, central region - - - 0.0000000000000001153 81.0
PYH3_k127_6001749_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000008206 70.0
PYH3_k127_6001749_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0005536 46.0
PYH3_k127_6057427_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 457.0
PYH3_k127_6057427_1 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000006141 181.0
PYH3_k127_6057427_2 KR domain - - - 0.00000000000000000000000000000000000000000000001955 172.0
PYH3_k127_6060670_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000003952 226.0
PYH3_k127_6060670_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000008664 151.0
PYH3_k127_6084275_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 586.0
PYH3_k127_6084275_1 Flagellar assembly protein FliH K02411 - - 0.000000000000000000000008059 110.0
PYH3_k127_6084275_2 flagellar export protein FliJ K02413 - - 0.0000000003962 66.0
PYH3_k127_6093246_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 396.0
PYH3_k127_6093246_1 HI0933-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 377.0
PYH3_k127_6093246_2 Domain of unknown function (DUF4863) - - - 0.00000000000000000000000000000000000000000000000002358 185.0
PYH3_k127_6093246_3 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000004129 175.0
PYH3_k127_6093246_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000004244 149.0
PYH3_k127_6093246_5 AMP-binding enzyme K12508 - 6.2.1.34 0.00000000000002414 75.0
PYH3_k127_6093246_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.00000000001141 65.0
PYH3_k127_6093246_7 AMP-binding enzyme K12508 - 6.2.1.34 0.00000000005024 73.0
PYH3_k127_6123049_0 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 569.0
PYH3_k127_6123049_1 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 485.0
PYH3_k127_6123049_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 325.0
PYH3_k127_6123049_3 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001317 261.0
PYH3_k127_6123049_4 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000003607 193.0
PYH3_k127_6123049_5 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000002581 121.0
PYH3_k127_6123049_6 Cytochrome c, class I - - - 0.0000000000000000000000003577 108.0
PYH3_k127_6124337_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 318.0
PYH3_k127_6124337_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
PYH3_k127_6124337_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000003118 179.0
PYH3_k127_6124337_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001781 173.0
PYH3_k127_6124337_4 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000004969 123.0
PYH3_k127_6124337_5 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000009797 133.0
PYH3_k127_6124337_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000001111 59.0
PYH3_k127_6142459_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000539 264.0
PYH3_k127_6142459_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000001435 227.0
PYH3_k127_6142459_2 transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000000008342 192.0
PYH3_k127_6211267_0 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 497.0
PYH3_k127_6211267_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000387 287.0
PYH3_k127_6211267_2 Lysin motif - - - 0.00000000000000000000000000000000001067 145.0
PYH3_k127_6214106_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 430.0
PYH3_k127_6214106_1 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
PYH3_k127_6214106_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000001718 184.0
PYH3_k127_6214106_3 - - - - 0.000000000000000000003137 101.0
PYH3_k127_6218545_0 Sodium/calcium exchanger protein K07301 - - 2.557e-206 644.0
PYH3_k127_6218545_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 641.0
PYH3_k127_6218545_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 611.0
PYH3_k127_6218545_3 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 579.0
PYH3_k127_6218545_4 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 516.0
PYH3_k127_6218545_5 Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 300.0
PYH3_k127_6218545_6 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000000000000002455 223.0
PYH3_k127_6218545_7 - - - - 0.00000000000000000000000000000000000000000000000000000000007433 207.0
PYH3_k127_6218545_8 - - - - 0.0000000000000000000000000000000000000000000000000000000001108 206.0
PYH3_k127_6218545_9 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000000000009306 124.0
PYH3_k127_6260414_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 486.0
PYH3_k127_6260414_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 422.0
PYH3_k127_6260414_2 Integrase - - - 0.000000000000000000000000000000000000000005019 156.0
PYH3_k127_6260414_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000002026 73.0
PYH3_k127_6290453_0 Belongs to the peptidase M16 family K07263 - - 3.613e-270 852.0
PYH3_k127_6290453_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 363.0
PYH3_k127_6290453_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000001513 235.0
PYH3_k127_6290453_11 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000007121 175.0
PYH3_k127_6290453_12 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000006162 170.0
PYH3_k127_6290453_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004544 168.0
PYH3_k127_6290453_14 - - - - 0.0000000000000000000000000000000009994 132.0
PYH3_k127_6290453_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000001297 84.0
PYH3_k127_6290453_16 Domain of unknown function (DUF4936) - - - 0.000009038 57.0
PYH3_k127_6290453_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 338.0
PYH3_k127_6290453_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 322.0
PYH3_k127_6290453_4 Aminomethyltransferase folate-binding domain K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001548 263.0
PYH3_k127_6290453_5 proteins homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000008254 257.0
PYH3_k127_6290453_6 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000009834 254.0
PYH3_k127_6290453_7 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007653 246.0
PYH3_k127_6290453_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000007865 239.0
PYH3_k127_6290453_9 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000002475 232.0
PYH3_k127_6323005_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 298.0
PYH3_k127_6323005_1 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006106 266.0
PYH3_k127_6337805_0 helicase K03657 - 3.6.4.12 1.758e-292 912.0
PYH3_k127_6337805_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 4.076e-230 726.0
PYH3_k127_6337805_10 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 363.0
PYH3_k127_6337805_11 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 355.0
PYH3_k127_6337805_12 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 343.0
PYH3_k127_6337805_13 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 334.0
PYH3_k127_6337805_14 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 325.0
PYH3_k127_6337805_15 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
PYH3_k127_6337805_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002008 272.0
PYH3_k127_6337805_17 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000153 268.0
PYH3_k127_6337805_18 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005124 258.0
PYH3_k127_6337805_19 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006042 263.0
PYH3_k127_6337805_2 phospholipase C - - - 3.546e-227 723.0
PYH3_k127_6337805_20 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000006807 246.0
PYH3_k127_6337805_21 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000009465 234.0
PYH3_k127_6337805_22 Aminotransferase K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000005092 184.0
PYH3_k127_6337805_23 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000002059 172.0
PYH3_k127_6337805_24 Endoribonuclease L-PSP - - - 0.00000000000000000000000000008332 121.0
PYH3_k127_6337805_25 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000001759 95.0
PYH3_k127_6337805_26 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000001754 67.0
PYH3_k127_6337805_28 ATPases associated with a variety of cellular activities K01996 - - 0.0000001694 56.0
PYH3_k127_6337805_29 Nucleotidyltransferase domain K07075 - - 0.000001775 51.0
PYH3_k127_6337805_3 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 5.568e-214 679.0
PYH3_k127_6337805_30 branched-chain amino acid K01996 - - 0.00009942 49.0
PYH3_k127_6337805_4 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 2.03e-205 653.0
PYH3_k127_6337805_5 Receptor family ligand binding region K01999 - - 2.167e-200 630.0
PYH3_k127_6337805_6 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 525.0
PYH3_k127_6337805_7 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 510.0
PYH3_k127_6337805_8 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 456.0
PYH3_k127_6337805_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 380.0
PYH3_k127_6347109_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000007711 224.0
PYH3_k127_6347109_1 - - - - 0.0000000000000000000000000000000000000001768 167.0
PYH3_k127_6347109_2 glycosyl transferase family 8 - - - 0.00000000000000000000000000007103 121.0
PYH3_k127_6359305_0 cysteine protease - - - 2.923e-236 749.0
PYH3_k127_6359305_1 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 513.0
PYH3_k127_6359305_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 487.0
PYH3_k127_6359305_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 432.0
PYH3_k127_6359305_4 AMP-binding enzyme C-terminal domain K16029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 370.0
PYH3_k127_6359305_5 - - - - 0.0000000000000000000000000000000000000000000000000000000001125 209.0
PYH3_k127_6359305_6 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.000000000000000000000000000000000000000000000003774 179.0
PYH3_k127_6359305_7 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000001146 182.0
PYH3_k127_6359305_8 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.00000000000000000000000000000006671 127.0
PYH3_k127_6359305_9 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000003534 126.0
PYH3_k127_6361656_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.784e-304 937.0
PYH3_k127_6361656_1 PrkA AAA domain K07180 - - 2.805e-279 872.0
PYH3_k127_6361656_10 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 507.0
PYH3_k127_6361656_11 Group II intron, maturase-specific domain K00986,K15342 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 493.0
PYH3_k127_6361656_12 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 481.0
PYH3_k127_6361656_13 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 461.0
PYH3_k127_6361656_14 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
PYH3_k127_6361656_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
PYH3_k127_6361656_16 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 419.0
PYH3_k127_6361656_17 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 410.0
PYH3_k127_6361656_18 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 408.0
PYH3_k127_6361656_19 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 409.0
PYH3_k127_6361656_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.863e-256 810.0
PYH3_k127_6361656_20 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 402.0
PYH3_k127_6361656_21 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 389.0
PYH3_k127_6361656_22 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 356.0
PYH3_k127_6361656_23 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 349.0
PYH3_k127_6361656_24 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 353.0
PYH3_k127_6361656_25 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 327.0
PYH3_k127_6361656_26 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
PYH3_k127_6361656_27 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 310.0
PYH3_k127_6361656_28 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001904 264.0
PYH3_k127_6361656_29 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002568 252.0
PYH3_k127_6361656_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.386e-231 719.0
PYH3_k127_6361656_30 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004874 253.0
PYH3_k127_6361656_31 peptidase, M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002825 263.0
PYH3_k127_6361656_32 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000001925 239.0
PYH3_k127_6361656_33 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000002033 244.0
PYH3_k127_6361656_34 cytochrome C oxidase K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000003731 241.0
PYH3_k127_6361656_35 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000009567 252.0
PYH3_k127_6361656_36 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
PYH3_k127_6361656_37 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000224 227.0
PYH3_k127_6361656_38 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000006978 218.0
PYH3_k127_6361656_39 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000008295 232.0
PYH3_k127_6361656_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.639e-211 667.0
PYH3_k127_6361656_40 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000008575 218.0
PYH3_k127_6361656_41 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000001274 216.0
PYH3_k127_6361656_42 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000732 196.0
PYH3_k127_6361656_43 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000000008172 192.0
PYH3_k127_6361656_44 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000002485 191.0
PYH3_k127_6361656_45 Cell division ATP-binding protein ftsE K09812 - - 0.00000000000000000000000000000000000000000000000001791 188.0
PYH3_k127_6361656_46 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000005536 179.0
PYH3_k127_6361656_47 SURF1-like protein - - - 0.000000000000000000000000000000000000000000004255 175.0
PYH3_k127_6361656_48 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000001139 172.0
PYH3_k127_6361656_49 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000004351 149.0
PYH3_k127_6361656_5 Peptidase family S49 K04773 - - 7.825e-211 672.0
PYH3_k127_6361656_50 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000003851 143.0
PYH3_k127_6361656_51 Protein of unknown function (DUF3299) K09950 - - 0.00000000000000000000000000000000003418 144.0
PYH3_k127_6361656_52 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000004182 138.0
PYH3_k127_6361656_53 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000001477 136.0
PYH3_k127_6361656_54 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000003084 132.0
PYH3_k127_6361656_55 Conserved hypothetical protein 95 - - - 0.0000000000000000000006669 109.0
PYH3_k127_6361656_56 Integral membrane protein (DUF2244) - - - 0.000000000000000000001752 99.0
PYH3_k127_6361656_57 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000006446 95.0
PYH3_k127_6361656_58 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000005576 85.0
PYH3_k127_6361656_6 SpoVR family K06415 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 556.0
PYH3_k127_6361656_60 Protein of unknown function (DUF2970) - - - 0.000000000000001848 84.0
PYH3_k127_6361656_61 - - - - 0.00000000000001832 76.0
PYH3_k127_6361656_62 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000007934 83.0
PYH3_k127_6361656_63 Heavy-metal-associated domain - - - 0.0000000000002072 74.0
PYH3_k127_6361656_64 Protein of unknown function (DUF2909) - - - 0.0000000000007326 72.0
PYH3_k127_6361656_65 - - - - 0.000005545 57.0
PYH3_k127_6361656_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 541.0
PYH3_k127_6361656_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 512.0
PYH3_k127_6361656_9 Cobalamin biosynthesis protein CobW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 499.0
PYH3_k127_6377355_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1017.0
PYH3_k127_6377355_1 Hydroxymethylglutaryl-CoA lyase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 443.0
PYH3_k127_6377355_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 420.0
PYH3_k127_6377355_3 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 350.0
PYH3_k127_6377355_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 327.0
PYH3_k127_6377355_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 260.0
PYH3_k127_6377355_6 - - - - 0.00000000000000000000000000000000000004238 163.0
PYH3_k127_6377355_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000521 145.0
PYH3_k127_6377355_8 HNH nucleases - - - 0.00001142 51.0
PYH3_k127_6443656_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1999.0
PYH3_k127_6443656_1 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1367.0
PYH3_k127_6443656_2 FAD binding domain - - - 0.0 1139.0
PYH3_k127_6443656_3 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 5.343e-218 691.0
PYH3_k127_6443656_4 Magnesium transport protein CorA - - - 6.389e-213 674.0
PYH3_k127_6443656_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
PYH3_k127_6443656_6 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000009933 188.0
PYH3_k127_6443656_7 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000000000000002964 143.0
PYH3_k127_6443656_8 ABC-type dipeptide transport system, periplasmic component - - - 0.000000000000000005618 90.0
PYH3_k127_6453209_0 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
PYH3_k127_6453209_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 366.0
PYH3_k127_6453209_2 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 319.0
PYH3_k127_6453209_3 Glycosyl transferase 4-like domain K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 314.0
PYH3_k127_6453209_4 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000348 293.0
PYH3_k127_6453209_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000004573 222.0
PYH3_k127_6453209_6 Glycosyltransferase like family 2 K13005 - 2.4.1.60 0.0000000000000000000000000000000000007558 152.0
PYH3_k127_6453209_7 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000001147 114.0
PYH3_k127_6453209_8 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000002168 114.0
PYH3_k127_6476731_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 4.361e-307 953.0
PYH3_k127_6476731_1 Sodium calcium K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 480.0
PYH3_k127_6476731_10 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.00000000006606 64.0
PYH3_k127_6476731_11 PFAM Methyltransferase type 11 - - - 0.000000001615 66.0
PYH3_k127_6476731_12 ATP-grasp domain - - - 0.00000203 56.0
PYH3_k127_6476731_13 - - - - 0.00001912 52.0
PYH3_k127_6476731_14 ubiE/COQ5 methyltransferase family - - - 0.00004667 52.0
PYH3_k127_6476731_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 396.0
PYH3_k127_6476731_3 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 370.0
PYH3_k127_6476731_4 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 325.0
PYH3_k127_6476731_5 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
PYH3_k127_6476731_6 DNA recombination protein, rmuC K09760 - - 0.000000000000000000000000000000000000000000000000000001165 202.0
PYH3_k127_6476731_7 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000004001 193.0
PYH3_k127_6476731_8 Putative transposase - - - 0.00000000000009527 81.0
PYH3_k127_6476731_9 Putative transposase - - - 0.000000000001344 69.0
PYH3_k127_6484375_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.232e-270 841.0
PYH3_k127_6484375_1 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 605.0
PYH3_k127_6484375_11 - - - - 0.00001145 50.0
PYH3_k127_6484375_2 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 503.0
PYH3_k127_6484375_3 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 419.0
PYH3_k127_6484375_5 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006331 278.0
PYH3_k127_6484375_6 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001349 251.0
PYH3_k127_6484375_7 - - - - 0.000000000000000000000000000002609 124.0
PYH3_k127_6484375_8 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000004259 116.0
PYH3_k127_6484375_9 SnoaL-like domain - - - 0.00000000002262 70.0
PYH3_k127_6484725_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1085.0
PYH3_k127_6484725_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 542.0
PYH3_k127_6484725_10 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 289.0
PYH3_k127_6484725_11 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000001039 224.0
PYH3_k127_6484725_12 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000001795 178.0
PYH3_k127_6484725_13 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000001169 150.0
PYH3_k127_6484725_14 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000006218 141.0
PYH3_k127_6484725_15 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000009631 134.0
PYH3_k127_6484725_16 PFAM thioesterase superfamily protein K01075 - 3.1.2.23 0.0000000000000000000000000001554 120.0
PYH3_k127_6484725_17 Domain of unknown function (DUF1992) - - - 0.00000000000000000000001561 106.0
PYH3_k127_6484725_18 Cysteine rich repeat - - - 0.000001016 60.0
PYH3_k127_6484725_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 497.0
PYH3_k127_6484725_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 453.0
PYH3_k127_6484725_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 421.0
PYH3_k127_6484725_5 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 418.0
PYH3_k127_6484725_6 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 384.0
PYH3_k127_6484725_7 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 333.0
PYH3_k127_6484725_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 307.0
PYH3_k127_6484725_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 294.0
PYH3_k127_6533080_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.866e-253 797.0
PYH3_k127_6533080_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 7.605e-232 731.0
PYH3_k127_6533080_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 346.0
PYH3_k127_6533080_11 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
PYH3_k127_6533080_12 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 301.0
PYH3_k127_6533080_13 Cytochrome B561 - - - 0.0000000000000000000000000000000000000000000000000000000000003585 218.0
PYH3_k127_6533080_14 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000008654 154.0
PYH3_k127_6533080_15 Preprotein translocase K03210 - - 0.00000000000000000000000000000006275 128.0
PYH3_k127_6533080_16 PFAM cytochrome c - - - 0.0000000000000002777 80.0
PYH3_k127_6533080_18 OsmC-like protein - - - 0.0002036 47.0
PYH3_k127_6533080_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 582.0
PYH3_k127_6533080_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 452.0
PYH3_k127_6533080_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 431.0
PYH3_k127_6533080_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 425.0
PYH3_k127_6533080_6 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 426.0
PYH3_k127_6533080_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 444.0
PYH3_k127_6533080_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 405.0
PYH3_k127_6533080_9 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 356.0
PYH3_k127_6545468_0 Multidrug ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 437.0
PYH3_k127_6545468_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 429.0
PYH3_k127_6545468_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 371.0
PYH3_k127_6545468_3 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 324.0
PYH3_k127_6545468_4 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 0.0000000000000000000000000000000000000000000000003962 179.0
PYH3_k127_6547643_0 oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 436.0
PYH3_k127_6547643_1 Glycine cleavage H-protein - - - 0.000000000000000000000003929 108.0
PYH3_k127_6547643_2 DsrE/DsrF-like family - - - 0.0000000000002572 79.0
PYH3_k127_6566401_0 L-carnitine dehydratase bile acid-inducible protein F - - - 4.232e-195 615.0
PYH3_k127_6566401_1 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 344.0
PYH3_k127_6566401_2 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000001895 103.0
PYH3_k127_6566401_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000002006 87.0
PYH3_k127_6576085_0 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 351.0
PYH3_k127_6576085_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000005347 88.0
PYH3_k127_6597441_0 PFAM Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 398.0
PYH3_k127_6597441_1 GON domain - - - 0.00000000000000000000000000000000000000002625 171.0
PYH3_k127_6597441_2 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000003132 104.0
PYH3_k127_6597441_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000007972 98.0
PYH3_k127_6597441_4 Glucose / Sorbosone dehydrogenase - - - 0.00000001536 67.0
PYH3_k127_6608068_0 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 381.0
PYH3_k127_6608068_1 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
PYH3_k127_660919_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1049.0
PYH3_k127_660919_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 7.907e-282 878.0
PYH3_k127_660919_10 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 370.0
PYH3_k127_660919_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002285 273.0
PYH3_k127_660919_12 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001371 261.0
PYH3_k127_660919_13 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006132 239.0
PYH3_k127_660919_14 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000005726 221.0
PYH3_k127_660919_15 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
PYH3_k127_660919_16 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000003484 194.0
PYH3_k127_660919_17 2 iron, 2 sulfur cluster binding K22070,K22071 - - 0.00000000000000000000000000000000000000000000000001427 181.0
PYH3_k127_660919_18 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000002287 181.0
PYH3_k127_660919_19 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000001301 166.0
PYH3_k127_660919_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.228e-239 747.0
PYH3_k127_660919_20 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000006311 132.0
PYH3_k127_660919_21 nitrogen regulatory protein P-II - - - 0.000000000000000000000000003695 125.0
PYH3_k127_660919_22 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000002872 109.0
PYH3_k127_660919_23 - - - - 0.00000000003726 68.0
PYH3_k127_660919_24 - - - - 0.0000004473 61.0
PYH3_k127_660919_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.033e-228 711.0
PYH3_k127_660919_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.898e-212 674.0
PYH3_k127_660919_5 His Kinase A (phosphoacceptor) domain - - - 2.643e-194 645.0
PYH3_k127_660919_6 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 586.0
PYH3_k127_660919_7 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 556.0
PYH3_k127_660919_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 536.0
PYH3_k127_660919_9 permease K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
PYH3_k127_6620046_0 Sulfate transporter antisigma-factor antagonist STAS - - - 7.14e-274 848.0
PYH3_k127_6620046_1 AI-2E family transporter - - - 0.000000000001252 69.0
PYH3_k127_6648550_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 315.0
PYH3_k127_6648550_1 nUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000007093 194.0
PYH3_k127_6648550_2 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000002404 154.0
PYH3_k127_6648550_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000006386 148.0
PYH3_k127_6651299_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 5.443e-305 949.0
PYH3_k127_6651299_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.361e-255 790.0
PYH3_k127_6651299_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.321e-245 762.0
PYH3_k127_6651299_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 309.0
PYH3_k127_6651299_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001397 244.0
PYH3_k127_6651299_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000009484 168.0
PYH3_k127_6654344_0 beta' subunit K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 597.0
PYH3_k127_6654344_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 524.0
PYH3_k127_6654344_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 473.0
PYH3_k127_6654344_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 301.0
PYH3_k127_6654344_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000001153 160.0
PYH3_k127_6654344_5 Putative regulatory protein - - - 0.00000000000000000001843 93.0
PYH3_k127_666689_0 PFAM transposase IS66 - - - 1.422e-262 818.0
PYH3_k127_666689_1 PFAM IS66 Orf2 family protein - - - 0.00000000000000000000000000000000000000000000000000000001934 203.0
PYH3_k127_666689_2 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000000000000000000000006663 136.0
PYH3_k127_6667270_0 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 387.0
PYH3_k127_6667270_1 FAD dependent oxidoreductase central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
PYH3_k127_6695348_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.291e-261 823.0
PYH3_k127_6695348_1 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.752e-209 663.0
PYH3_k127_6695348_10 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000003584 154.0
PYH3_k127_6695348_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000006658 121.0
PYH3_k127_6695348_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000001217 84.0
PYH3_k127_6695348_2 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 571.0
PYH3_k127_6695348_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 563.0
PYH3_k127_6695348_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 499.0
PYH3_k127_6695348_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 475.0
PYH3_k127_6695348_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 397.0
PYH3_k127_6695348_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 308.0
PYH3_k127_6695348_8 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000000000000000000003988 201.0
PYH3_k127_6695348_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000217 172.0
PYH3_k127_6699127_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 6.768e-243 760.0
PYH3_k127_6699127_1 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 533.0
PYH3_k127_6699127_10 Aldehyde dehydrogenase K15514 - 1.2.1.77 0.00004389 46.0
PYH3_k127_6699127_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 421.0
PYH3_k127_6699127_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 402.0
PYH3_k127_6699127_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 406.0
PYH3_k127_6699127_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 366.0
PYH3_k127_6699127_6 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 344.0
PYH3_k127_6699127_7 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000002261 247.0
PYH3_k127_6699127_8 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
PYH3_k127_6699127_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000001791 122.0
PYH3_k127_6724917_0 sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 428.0
PYH3_k127_6724917_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 316.0
PYH3_k127_6724917_2 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000001019 165.0
PYH3_k127_6724917_3 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.0000000000000009978 77.0
PYH3_k127_6736012_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 536.0
PYH3_k127_6736012_1 - - - - 0.00000000000004102 76.0
PYH3_k127_6742263_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.714e-285 895.0
PYH3_k127_6742263_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.213e-272 849.0
PYH3_k127_6742263_10 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 328.0
PYH3_k127_6742263_11 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 299.0
PYH3_k127_6742263_12 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 299.0
PYH3_k127_6742263_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001667 273.0
PYH3_k127_6742263_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000008694 250.0
PYH3_k127_6742263_15 - - - - 0.000000000000000000000000000000000000007209 151.0
PYH3_k127_6742263_16 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000001883 117.0
PYH3_k127_6742263_2 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.872e-259 806.0
PYH3_k127_6742263_3 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 3.098e-211 671.0
PYH3_k127_6742263_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 554.0
PYH3_k127_6742263_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 504.0
PYH3_k127_6742263_6 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 492.0
PYH3_k127_6742263_7 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
PYH3_k127_6742263_8 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 413.0
PYH3_k127_6742263_9 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 337.0
PYH3_k127_6782354_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1461.0
PYH3_k127_6782354_1 PFAM FAD binding domain, FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 541.0
PYH3_k127_6782354_10 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000001205 126.0
PYH3_k127_6782354_11 Domain of unknown function (DUF4266) - - - 0.0000000000000000001561 96.0
PYH3_k127_6782354_12 Helix-turn-helix domain - - - 0.000000000000000001016 86.0
PYH3_k127_6782354_13 Phage integrase family - - - 0.00000000000000008147 81.0
PYH3_k127_6782354_14 Phage integrase family - - - 0.0000000000008189 74.0
PYH3_k127_6782354_15 Belongs to the 'phage' integrase family - - - 0.00000006821 57.0
PYH3_k127_6782354_16 Phage integrase family - - - 0.0000008969 51.0
PYH3_k127_6782354_17 Domain of unknown function (DUF4124) - - - 0.0001162 50.0
PYH3_k127_6782354_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 454.0
PYH3_k127_6782354_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
PYH3_k127_6782354_4 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 359.0
PYH3_k127_6782354_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 289.0
PYH3_k127_6782354_6 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 297.0
PYH3_k127_6782354_7 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
PYH3_k127_6782354_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
PYH3_k127_6782354_9 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003591 259.0
PYH3_k127_6825477_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 512.0
PYH3_k127_6825477_1 Plasmid stabilization system - - - 0.000000000000000003286 84.0
PYH3_k127_6825477_2 Methyltransferase - - - 0.0006253 47.0
PYH3_k127_6843341_0 Participates in both transcription termination and antitermination K02600 - - 1.639e-212 671.0
PYH3_k127_6843341_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 400.0
PYH3_k127_6843341_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 362.0
PYH3_k127_6843341_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000009647 167.0
PYH3_k127_6860476_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 429.0
PYH3_k127_6860476_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000001617 188.0
PYH3_k127_6860476_2 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000004247 108.0
PYH3_k127_687853_0 protein N-acetylglucosaminyltransferase activity - - - 1.606e-228 727.0
PYH3_k127_687853_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 606.0
PYH3_k127_687853_10 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 334.0
PYH3_k127_687853_11 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 309.0
PYH3_k127_687853_12 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 264.0
PYH3_k127_687853_13 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 259.0
PYH3_k127_687853_14 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 257.0
PYH3_k127_687853_15 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
PYH3_k127_687853_16 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000000000000000000006364 231.0
PYH3_k127_687853_17 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
PYH3_k127_687853_18 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000005031 216.0
PYH3_k127_687853_19 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000001371 211.0
PYH3_k127_687853_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 561.0
PYH3_k127_687853_20 - - - - 0.0000000000000000000000000000000000000000000000000000000002609 214.0
PYH3_k127_687853_21 Phosphoglycerate mutase K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000455 203.0
PYH3_k127_687853_22 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000005162 207.0
PYH3_k127_687853_23 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000008948 211.0
PYH3_k127_687853_24 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000003245 197.0
PYH3_k127_687853_25 Gram-negative porin K03285 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000004833 189.0
PYH3_k127_687853_26 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000002136 178.0
PYH3_k127_687853_27 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000001087 138.0
PYH3_k127_687853_28 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000008729 123.0
PYH3_k127_687853_29 Hsp20/alpha crystallin family - - - 0.000000000000000000000000003485 116.0
PYH3_k127_687853_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 496.0
PYH3_k127_687853_30 CAAX protease self-immunity K07052 - - 0.0000000000000000000000007316 113.0
PYH3_k127_687853_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 492.0
PYH3_k127_687853_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 480.0
PYH3_k127_687853_6 NADH:flavin oxidoreductase / NADH oxidase family K00354 - 1.6.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 472.0
PYH3_k127_687853_7 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 479.0
PYH3_k127_687853_8 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 395.0
PYH3_k127_687853_9 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 390.0
PYH3_k127_6886656_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1216.0
PYH3_k127_6886656_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 614.0
PYH3_k127_6886656_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 470.0
PYH3_k127_6886656_3 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000002157 56.0
PYH3_k127_6897878_0 Extracellular solute-binding protein K17321 - - 7e-323 997.0
PYH3_k127_6897878_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 3.446e-314 981.0
PYH3_k127_6897878_10 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 355.0
PYH3_k127_6897878_11 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
PYH3_k127_6897878_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 289.0
PYH3_k127_6897878_13 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
PYH3_k127_6897878_14 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001256 248.0
PYH3_k127_6897878_15 [2Fe-2S] binding domain K04107 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000002609 237.0
PYH3_k127_6897878_16 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000000000000000000000002523 226.0
PYH3_k127_6897878_17 PFAM Cytochrome c, class I K08738 - - 0.000000000000000000000000000000000000000000000000001241 186.0
PYH3_k127_6897878_18 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000005375 188.0
PYH3_k127_6897878_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000008492 157.0
PYH3_k127_6897878_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 608.0
PYH3_k127_6897878_20 transcriptional regulator - - - 0.0000000000000000000000000000000001207 137.0
PYH3_k127_6897878_21 small integral membrane protein - - - 0.00000000000000000000000000000001196 130.0
PYH3_k127_6897878_22 Thioesterase - - - 0.000000000000000000000000000005538 124.0
PYH3_k127_6897878_23 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000003967 127.0
PYH3_k127_6897878_24 Hemerythrin HHE cation binding domain - - - 0.000000000000000001364 93.0
PYH3_k127_6897878_25 amine dehydrogenase activity K13730 - - 0.00000003448 65.0
PYH3_k127_6897878_3 Binding-protein-dependent transport system inner membrane component K17323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 482.0
PYH3_k127_6897878_4 Belongs to the ABC transporter superfamily K17325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 477.0
PYH3_k127_6897878_5 permease K17322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 460.0
PYH3_k127_6897878_6 Belongs to the ABC transporter superfamily K17324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 437.0
PYH3_k127_6897878_7 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 361.0
PYH3_k127_6897878_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 357.0
PYH3_k127_6897878_9 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 349.0
PYH3_k127_6901651_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 576.0
PYH3_k127_6901651_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002182 265.0
PYH3_k127_6901651_2 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
PYH3_k127_6901651_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000005113 199.0
PYH3_k127_6901651_4 DNA-binding - - - 0.00000000000000000000000000000000000000000000000000001114 195.0
PYH3_k127_6901651_5 - - - - 0.00000000000000000000000000000000000003275 151.0
PYH3_k127_6901651_6 Dienelactone hydrolase family - - - 0.000000000002988 70.0
PYH3_k127_6935806_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 554.0
PYH3_k127_6935806_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 531.0
PYH3_k127_6935806_10 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
PYH3_k127_6935806_11 tetR family - - - 0.0000000000000000000000000000000000000000000000000000002002 202.0
PYH3_k127_6935806_12 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000005268 194.0
PYH3_k127_6935806_13 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000006138 160.0
PYH3_k127_6935806_14 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000008365 139.0
PYH3_k127_6935806_15 - - - - 0.0000000000000000000000000001354 129.0
PYH3_k127_6935806_16 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000001731 106.0
PYH3_k127_6935806_17 Phospholipid methyltransferase - - - 0.000000000000004369 81.0
PYH3_k127_6935806_18 Heavy-metal resistance - - - 0.0000000000000625 81.0
PYH3_k127_6935806_2 Trypsin K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 477.0
PYH3_k127_6935806_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 453.0
PYH3_k127_6935806_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 417.0
PYH3_k127_6935806_5 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 387.0
PYH3_k127_6935806_6 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 363.0
PYH3_k127_6935806_7 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 327.0
PYH3_k127_6935806_8 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 333.0
PYH3_k127_6935806_9 Two component transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 299.0
PYH3_k127_6947936_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 323.0
PYH3_k127_6980104_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000006995 238.0
PYH3_k127_6980104_1 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000002644 141.0
PYH3_k127_6985406_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 368.0
PYH3_k127_6985406_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001126 261.0
PYH3_k127_6985406_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000006648 109.0
PYH3_k127_7048879_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5e-324 998.0
PYH3_k127_7048879_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.531e-282 879.0
PYH3_k127_7048879_10 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 411.0
PYH3_k127_7048879_11 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 392.0
PYH3_k127_7048879_12 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 386.0
PYH3_k127_7048879_13 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 387.0
PYH3_k127_7048879_14 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 375.0
PYH3_k127_7048879_15 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 392.0
PYH3_k127_7048879_16 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 359.0
PYH3_k127_7048879_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 353.0
PYH3_k127_7048879_18 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
PYH3_k127_7048879_19 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
PYH3_k127_7048879_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.913e-247 780.0
PYH3_k127_7048879_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
PYH3_k127_7048879_21 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000047 280.0
PYH3_k127_7048879_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003135 256.0
PYH3_k127_7048879_23 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 254.0
PYH3_k127_7048879_24 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002742 267.0
PYH3_k127_7048879_25 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
PYH3_k127_7048879_26 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000004871 241.0
PYH3_k127_7048879_27 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000002489 216.0
PYH3_k127_7048879_28 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000003896 160.0
PYH3_k127_7048879_29 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000001495 152.0
PYH3_k127_7048879_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.036e-213 680.0
PYH3_k127_7048879_30 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000009099 150.0
PYH3_k127_7048879_31 Tautomerase enzyme - - - 0.0000000000000000000000000000000000004934 149.0
PYH3_k127_7048879_32 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000009519 135.0
PYH3_k127_7048879_33 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000002759 112.0
PYH3_k127_7048879_34 Domain of unknown function (DUF4845) - - - 0.00000000000000000000001732 104.0
PYH3_k127_7048879_35 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000006551 97.0
PYH3_k127_7048879_36 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.0000000000003486 77.0
PYH3_k127_7048879_37 - - - - 0.000000000004497 70.0
PYH3_k127_7048879_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.579e-205 643.0
PYH3_k127_7048879_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 548.0
PYH3_k127_7048879_6 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 525.0
PYH3_k127_7048879_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 446.0
PYH3_k127_7048879_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 441.0
PYH3_k127_7048879_9 Domain of unknown function (DUF3394) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 430.0
PYH3_k127_7069991_0 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 423.0
PYH3_k127_7069991_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000009795 188.0
PYH3_k127_7069991_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000003874 175.0
PYH3_k127_7069991_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000005498 130.0
PYH3_k127_7105553_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1762.0
PYH3_k127_7105553_1 efflux pump K18138,K18146 - - 0.0 1454.0
PYH3_k127_7105553_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 395.0
PYH3_k127_7105553_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 377.0
PYH3_k127_7105553_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 320.0
PYH3_k127_7105553_13 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003426 243.0
PYH3_k127_7105553_14 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
PYH3_k127_7105553_15 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000765 198.0
PYH3_k127_7105553_16 Thioesterase K07107,K12500 - - 0.000000000000000000000000000000000000000000000000000001314 195.0
PYH3_k127_7105553_17 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000009272 183.0
PYH3_k127_7105553_18 repressor for the acrAB genes K03577 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000003385 172.0
PYH3_k127_7105553_19 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000005169 164.0
PYH3_k127_7105553_2 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 9.188e-221 692.0
PYH3_k127_7105553_20 Ribbon-helix-helix domain - - - 0.00000000000000000000000000000000000000000248 158.0
PYH3_k127_7105553_21 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000007592 125.0
PYH3_k127_7105553_22 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000001321 125.0
PYH3_k127_7105553_23 - - - - 0.0000000000000000000000000004871 116.0
PYH3_k127_7105553_24 SMART Cold shock protein K03704 - - 0.000000000000000000000000001016 113.0
PYH3_k127_7105553_3 e1 component (alpha subunit) K00166 - 1.2.4.4 1.17e-199 630.0
PYH3_k127_7105553_4 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 607.0
PYH3_k127_7105553_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 560.0
PYH3_k127_7105553_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 545.0
PYH3_k127_7105553_7 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 520.0
PYH3_k127_7105553_8 Fic/DOC family N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 486.0
PYH3_k127_7105553_9 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 400.0
PYH3_k127_7109380_0 type II secretion system protein E K02454,K02652 - - 5.128e-209 659.0
PYH3_k127_7109380_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.593e-203 642.0
PYH3_k127_7109380_10 General Secretory Pathway K02463 - - 0.0000000000000000000000000000000000000000371 161.0
PYH3_k127_7109380_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000782 146.0
PYH3_k127_7109380_12 Cytochrome c K08738 - - 0.000000000000000000000000000003982 126.0
PYH3_k127_7109380_13 General secretion pathway protein L K02461 - - 0.0000000000000000000000000009698 127.0
PYH3_k127_7109380_14 general secretion pathway protein K02457 - - 0.00000000000000000000000008021 113.0
PYH3_k127_7109380_15 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000000003104 95.0
PYH3_k127_7109380_16 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000007023 86.0
PYH3_k127_7109380_17 ChrR Cupin-like domain - - - 0.000000000000000001872 93.0
PYH3_k127_7109380_18 general secretion pathway protein K02459 - - 0.000000000000000008607 94.0
PYH3_k127_7109380_19 General secretion pathway K02462 - - 0.0000000000000001005 86.0
PYH3_k127_7109380_2 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 630.0
PYH3_k127_7109380_20 Anti-sigma factor - - - 0.00000000000002905 78.0
PYH3_k127_7109380_21 general secretion pathway protein K02452 - - 0.00000000004007 71.0
PYH3_k127_7109380_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 496.0
PYH3_k127_7109380_4 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 434.0
PYH3_k127_7109380_5 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
PYH3_k127_7109380_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 298.0
PYH3_k127_7109380_7 Domain of unknown function (DUF4439) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004274 236.0
PYH3_k127_7109380_8 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000003812 209.0
PYH3_k127_7109380_9 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000002465 206.0
PYH3_k127_7111439_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 403.0
PYH3_k127_7111439_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 286.0
PYH3_k127_7129699_0 Dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 1.044e-199 627.0
PYH3_k127_7129699_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 597.0
PYH3_k127_7129699_2 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 434.0
PYH3_k127_7129699_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00001508 51.0
PYH3_k127_7131493_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1171.0
PYH3_k127_7131493_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.935e-245 769.0
PYH3_k127_7131493_10 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000000008174 194.0
PYH3_k127_7131493_11 Flagellar motor switch protein FliN K02417,K03225 - - 0.0000000000000000000000000000000000000000007433 167.0
PYH3_k127_7131493_12 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000006907 119.0
PYH3_k127_7131493_13 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000008288 117.0
PYH3_k127_7131493_14 membrane - - - 0.000000000000000000004646 101.0
PYH3_k127_7131493_15 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000006715 72.0
PYH3_k127_7131493_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 606.0
PYH3_k127_7131493_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 529.0
PYH3_k127_7131493_4 Flagellar motor switch K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 436.0
PYH3_k127_7131493_5 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 374.0
PYH3_k127_7131493_6 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 309.0
PYH3_k127_7131493_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 286.0
PYH3_k127_7131493_8 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000004061 234.0
PYH3_k127_7131493_9 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000000000000000000000006892 226.0
PYH3_k127_7137261_0 Integrase core domain K07497 - - 0.000000000000000000000006155 101.0
PYH3_k127_7137261_1 Integrase core domain K07497 - - 0.00000000000000000001027 94.0
PYH3_k127_7137261_2 Methyltransferase domain - - - 0.000000000000008076 77.0
PYH3_k127_7137261_3 - - - - 0.00000000000668 76.0
PYH3_k127_7193865_0 4Fe-4S dicluster domain K18930 - - 0.0 1164.0
PYH3_k127_7193865_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 531.0
PYH3_k127_7193865_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 439.0
PYH3_k127_7193865_3 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 317.0
PYH3_k127_7193865_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000003611 198.0
PYH3_k127_7193865_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000001802 141.0
PYH3_k127_7193865_6 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000009104 69.0
PYH3_k127_7193865_7 Protein of unknown function (DUF1439) - - - 0.0001824 51.0
PYH3_k127_7230475_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 580.0
PYH3_k127_7230475_1 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 372.0
PYH3_k127_7230475_2 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 319.0
PYH3_k127_7230475_3 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 310.0
PYH3_k127_7230475_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001499 280.0
PYH3_k127_7230475_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000181 201.0
PYH3_k127_7230475_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000398 171.0
PYH3_k127_7230475_7 Protein of unknown function (DUF2783) - - - 0.0000000000000002826 81.0
PYH3_k127_7230475_8 - - - - 0.0005322 47.0
PYH3_k127_7230475_9 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.000686 44.0
PYH3_k127_7235819_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 2.57e-204 642.0
PYH3_k127_7235819_1 Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000000000000000000000000002531 181.0
PYH3_k127_7235819_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000047 123.0
PYH3_k127_7235819_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000129 112.0
PYH3_k127_7235819_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000002499 89.0
PYH3_k127_7235819_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000562 63.0
PYH3_k127_7235819_6 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000000001551 65.0
PYH3_k127_7240069_0 Ammonium Transporter Family K03320,K06580 - - 8.308e-219 685.0
PYH3_k127_7240069_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 507.0
PYH3_k127_7240069_2 PFAM MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 400.0
PYH3_k127_7240069_3 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000000000132 231.0
PYH3_k127_7240069_4 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000002372 199.0
PYH3_k127_7240069_5 Cytochrome c K17223 - - 0.00000000000000000000038 109.0
PYH3_k127_725707_0 PFAM Glycosyl transferase, family 2 - - - 0.0 1129.0
PYH3_k127_725707_1 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 4.303e-213 670.0
PYH3_k127_725707_10 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 474.0
PYH3_k127_725707_11 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 468.0
PYH3_k127_725707_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 448.0
PYH3_k127_725707_13 Belongs to the GPI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 409.0
PYH3_k127_725707_14 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 402.0
PYH3_k127_725707_15 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
PYH3_k127_725707_16 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 381.0
PYH3_k127_725707_17 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 363.0
PYH3_k127_725707_18 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 359.0
PYH3_k127_725707_19 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 367.0
PYH3_k127_725707_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 7.003e-211 662.0
PYH3_k127_725707_20 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 344.0
PYH3_k127_725707_21 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 314.0
PYH3_k127_725707_22 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 306.0
PYH3_k127_725707_23 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 284.0
PYH3_k127_725707_24 O-Methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006634 274.0
PYH3_k127_725707_25 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000459 271.0
PYH3_k127_725707_26 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003843 270.0
PYH3_k127_725707_27 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009466 263.0
PYH3_k127_725707_28 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000007665 256.0
PYH3_k127_725707_29 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
PYH3_k127_725707_3 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 591.0
PYH3_k127_725707_30 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 248.0
PYH3_k127_725707_31 phenylacetic acid degradation protein paaN - - - 0.000000000000000000000000000000000000000000000000000000000000000004956 234.0
PYH3_k127_725707_32 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000000000000142 222.0
PYH3_k127_725707_33 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.0000000000000000000000000000000000000000000000000000005788 194.0
PYH3_k127_725707_34 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000008891 198.0
PYH3_k127_725707_35 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.00000000000000000000000000000000000000000000000004986 186.0
PYH3_k127_725707_36 Membrane - - - 0.000000000000000000000000000000000000000000000005721 190.0
PYH3_k127_725707_37 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000007809 184.0
PYH3_k127_725707_38 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000003507 184.0
PYH3_k127_725707_39 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000001427 138.0
PYH3_k127_725707_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 592.0
PYH3_k127_725707_40 GtrA-like protein - - - 0.000000000000000000000000001519 121.0
PYH3_k127_725707_41 COGs COG2929 conserved K09803 - - 0.00000000000000000000004415 100.0
PYH3_k127_725707_42 - - - - 0.000000000000000000009206 108.0
PYH3_k127_725707_43 Glycosyl transferase family 2 - - - 0.00000000000000003823 86.0
PYH3_k127_725707_44 GtrA-like protein - - - 0.0000000000000004836 85.0
PYH3_k127_725707_45 Epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000002433 81.0
PYH3_k127_725707_46 - - - - 0.000000000007635 68.0
PYH3_k127_725707_47 histidine kinase A domain protein - - - 0.0000323 54.0
PYH3_k127_725707_48 Phenylacetic acid degradation protein PaaN - - - 0.0007342 50.0
PYH3_k127_725707_49 repeat-containing protein - - - 0.000752 48.0
PYH3_k127_725707_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 544.0
PYH3_k127_725707_6 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 557.0
PYH3_k127_725707_7 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 516.0
PYH3_k127_725707_8 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 514.0
PYH3_k127_725707_9 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 499.0
PYH3_k127_7271587_0 SNARE associated Golgi protein - - - 2.003e-316 985.0
PYH3_k127_7271587_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.347e-293 916.0
PYH3_k127_7271587_10 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002411 281.0
PYH3_k127_7271587_11 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005501 261.0
PYH3_k127_7271587_12 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006849 244.0
PYH3_k127_7271587_13 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008389 239.0
PYH3_k127_7271587_14 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
PYH3_k127_7271587_15 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000002805 178.0
PYH3_k127_7271587_16 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000002783 151.0
PYH3_k127_7271587_17 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000000000004749 155.0
PYH3_k127_7271587_19 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000003047 140.0
PYH3_k127_7271587_2 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 614.0
PYH3_k127_7271587_20 YHS domain protein - - - 0.000000000000000000000000000000008364 140.0
PYH3_k127_7271587_21 PIN domain - - - 0.0000000000000000000000000001013 121.0
PYH3_k127_7271587_22 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0000000000000000000000000008767 115.0
PYH3_k127_7271587_23 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000004543 114.0
PYH3_k127_7271587_24 Protein of unknown function (DUF1015) - - - 0.000000000000000001025 87.0
PYH3_k127_7271587_25 Acetoacetate decarboxylase (ADC) - - - 0.0000000000000005145 88.0
PYH3_k127_7271587_26 Amidohydrolase - - - 0.0000000000000009148 89.0
PYH3_k127_7271587_27 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.00000007717 57.0
PYH3_k127_7271587_28 positive regulation of growth - - - 0.00000008049 58.0
PYH3_k127_7271587_29 Transmembrane anti-sigma factor - - - 0.000007312 51.0
PYH3_k127_7271587_3 Belongs to the glycosyl hydrolase 13 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 594.0
PYH3_k127_7271587_4 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 567.0
PYH3_k127_7271587_5 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 451.0
PYH3_k127_7271587_6 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
PYH3_k127_7271587_7 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
PYH3_k127_7271587_8 Putative heavy-metal chelation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 336.0
PYH3_k127_7271587_9 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
PYH3_k127_7282026_0 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 1.432e-216 681.0
PYH3_k127_7282026_1 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 606.0
PYH3_k127_7282026_10 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 311.0
PYH3_k127_7282026_11 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005256 275.0
PYH3_k127_7282026_12 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000232 265.0
PYH3_k127_7282026_13 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
PYH3_k127_7282026_14 Phasin protein - - - 0.0000000000000000000000000000000000000001411 159.0
PYH3_k127_7282026_15 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000001437 105.0
PYH3_k127_7282026_16 - - - - 0.000000003243 63.0
PYH3_k127_7282026_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 410.0
PYH3_k127_7282026_3 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 392.0
PYH3_k127_7282026_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 379.0
PYH3_k127_7282026_5 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 380.0
PYH3_k127_7282026_6 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 368.0
PYH3_k127_7282026_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 348.0
PYH3_k127_7282026_8 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 347.0
PYH3_k127_7282026_9 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
PYH3_k127_7326883_0 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 593.0
PYH3_k127_7326883_1 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 402.0
PYH3_k127_7326883_2 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001362 284.0
PYH3_k127_7326883_3 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 276.0
PYH3_k127_7326883_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000007862 181.0
PYH3_k127_7326883_5 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000003167 130.0
PYH3_k127_7326883_6 Hemerythrin HHE cation binding domain - - - 0.0000000000000000001931 94.0
PYH3_k127_7326883_7 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000009244 56.0
PYH3_k127_7380229_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1309.0
PYH3_k127_7380229_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1274.0
PYH3_k127_7380229_10 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 447.0
PYH3_k127_7380229_11 THUMP domain K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 406.0
PYH3_k127_7380229_12 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 421.0
PYH3_k127_7380229_13 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 385.0
PYH3_k127_7380229_14 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 390.0
PYH3_k127_7380229_15 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 361.0
PYH3_k127_7380229_16 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
PYH3_k127_7380229_17 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 329.0
PYH3_k127_7380229_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 309.0
PYH3_k127_7380229_19 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 290.0
PYH3_k127_7380229_2 DNA helicase K03657 - 3.6.4.12 0.0 1028.0
PYH3_k127_7380229_20 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002577 278.0
PYH3_k127_7380229_21 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008755 252.0
PYH3_k127_7380229_22 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
PYH3_k127_7380229_23 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000005906 221.0
PYH3_k127_7380229_24 electron transfer activity K02305,K08738 - - 0.0000000000000000000000000000000000000000001099 168.0
PYH3_k127_7380229_25 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000001281 165.0
PYH3_k127_7380229_26 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000003985 153.0
PYH3_k127_7380229_27 Transcriptional - - - 0.0000000000000000000000000000000000000003537 159.0
PYH3_k127_7380229_28 Prokaryotic N-terminal methylation motif K02655 - - 0.0000000000000000000000000000000000003113 146.0
PYH3_k127_7380229_29 - - - - 0.000000000000000000000000000001299 131.0
PYH3_k127_7380229_3 Putative modulator of DNA gyrase - - - 3.121e-198 628.0
PYH3_k127_7380229_30 ABC transporter - - - 0.000000000005175 69.0
PYH3_k127_7380229_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 582.0
PYH3_k127_7380229_5 Pilus retraction K02669,K12203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 577.0
PYH3_k127_7380229_6 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 580.0
PYH3_k127_7380229_7 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 572.0
PYH3_k127_7380229_8 Tat pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 481.0
PYH3_k127_7380229_9 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 464.0
PYH3_k127_7380986_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 452.0
PYH3_k127_7380986_1 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 360.0
PYH3_k127_7380986_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000001915 55.0
PYH3_k127_7382661_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 535.0
PYH3_k127_7382661_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 526.0
PYH3_k127_7382661_2 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 367.0
PYH3_k127_7382661_3 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 291.0
PYH3_k127_7382661_4 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000008295 137.0
PYH3_k127_7382661_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000002393 95.0
PYH3_k127_7382661_6 - - - - 0.000000000006742 78.0
PYH3_k127_7382661_7 - - - - 0.00001162 57.0
PYH3_k127_7404842_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1355.0
PYH3_k127_7404842_1 Belongs to the transketolase family K00615 - 2.2.1.1 3.622e-299 934.0
PYH3_k127_7404842_10 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 442.0
PYH3_k127_7404842_11 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 341.0
PYH3_k127_7404842_12 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 292.0
PYH3_k127_7404842_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005522 270.0
PYH3_k127_7404842_14 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000553 219.0
PYH3_k127_7404842_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000002506 205.0
PYH3_k127_7404842_16 ribonuclease K01167 - 3.1.27.3 0.0000000000000000000000000000000000000249 148.0
PYH3_k127_7404842_17 Phosphoribulokinase K00855 - 2.7.1.19 0.0000000000000000000000000000001123 123.0
PYH3_k127_7404842_18 Tricorn protease C1 domain K03797 - 3.4.21.102 0.0000000000000000000000000000004258 139.0
PYH3_k127_7404842_19 Lysin motif - - - 0.000000000000000000000000000005375 132.0
PYH3_k127_7404842_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 2.764e-297 925.0
PYH3_k127_7404842_20 PFAM Patatin K07001 - - 0.0000000000000000000000001445 115.0
PYH3_k127_7404842_21 Barstar (barnase inhibitor) - - - 0.00000000000000000000003491 108.0
PYH3_k127_7404842_22 Rhomboid family - - - 0.00000000000000002832 91.0
PYH3_k127_7404842_23 Bacterial protein of unknown function (DUF937) - - - 0.0000000000003855 73.0
PYH3_k127_7404842_24 - - - - 0.000000009913 61.0
PYH3_k127_7404842_26 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000001716 55.0
PYH3_k127_7404842_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 3.469e-288 893.0
PYH3_k127_7404842_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.047e-224 710.0
PYH3_k127_7404842_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.155e-213 676.0
PYH3_k127_7404842_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 594.0
PYH3_k127_7404842_7 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 597.0
PYH3_k127_7404842_8 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 589.0
PYH3_k127_7404842_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 476.0
PYH3_k127_7427128_0 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 409.0
PYH3_k127_7427128_1 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000003827 60.0
PYH3_k127_7427128_2 Histone methylation protein DOT1 - - - 0.0000003456 54.0
PYH3_k127_7445020_0 ABC transporter transmembrane region K06147 - - 4.725e-274 861.0
PYH3_k127_7445020_1 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 413.0
PYH3_k127_7445020_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 382.0
PYH3_k127_7445020_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000003933 169.0
PYH3_k127_7445020_4 PFAM MAPEG family - - - 0.00000000000000000000000000000000000004565 149.0
PYH3_k127_7445020_5 - - - - 0.00000000000000000000000000000005172 131.0
PYH3_k127_7456652_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 586.0
PYH3_k127_7456652_1 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 481.0
PYH3_k127_7456652_2 Thioesterase - - - 0.000000000000000000000000000000000004536 141.0
PYH3_k127_7475340_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 5.22e-316 973.0
PYH3_k127_7475340_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.356e-271 846.0
PYH3_k127_7475340_10 - - - - 0.0000000000008586 72.0
PYH3_k127_7475340_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 491.0
PYH3_k127_7475340_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 350.0
PYH3_k127_7475340_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 330.0
PYH3_k127_7475340_5 ArgK protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
PYH3_k127_7475340_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000000000000000000002665 119.0
PYH3_k127_7475340_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000004511 94.0
PYH3_k127_7475340_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000007981 87.0
PYH3_k127_7475340_9 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000003154 74.0
PYH3_k127_7481082_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 529.0
PYH3_k127_7481082_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 535.0
PYH3_k127_7481082_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000124 271.0
PYH3_k127_7481082_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
PYH3_k127_7481082_4 amine dehydrogenase activity K13730 - - 0.0000000000000000000002693 97.0
PYH3_k127_7499794_0 to GP 6723233 - - - 3.443e-226 707.0
PYH3_k127_7499794_1 transposase K07497 - - 0.00000000000000000000000000000000000000000000000006758 182.0
PYH3_k127_7499794_2 transposase activity K07483 - - 0.0000000000000000000000000002957 118.0
PYH3_k127_7503266_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 497.0
PYH3_k127_7503266_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.00000000000000000000000009511 115.0
PYH3_k127_7503266_2 Uncharacterized protein family UPF0016 - - - 0.0000000000005831 69.0
PYH3_k127_7506824_0 ABC transporter K10441 - 3.6.3.17 1.388e-222 698.0
PYH3_k127_7506824_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 511.0
PYH3_k127_7506824_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 344.0
PYH3_k127_7506824_3 - - - - 0.00000000000000000000000000000000000000000000000000000008376 199.0
PYH3_k127_7506824_4 Putative lumazine-binding - - - 0.00000000000000000000000000000000000000000000000000002799 194.0
PYH3_k127_7506824_5 COG3436 Transposase and inactivated derivatives K07484 - - 0.000000000000000000000000000000000000000001094 163.0
PYH3_k127_7506824_6 COG2801 Transposase and inactivated derivatives - - - 0.0000002371 57.0
PYH3_k127_750734_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.981e-211 664.0
PYH3_k127_750734_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 604.0
PYH3_k127_750734_2 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000003212 109.0
PYH3_k127_7527936_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.042e-218 688.0
PYH3_k127_7527936_1 Cell shape determining protein, MreB Mrl family K03569 - - 1.292e-198 623.0
PYH3_k127_7527936_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
PYH3_k127_7527936_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 293.0
PYH3_k127_7527936_4 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000001468 234.0
PYH3_k127_7527936_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000006312 119.0
PYH3_k127_7545996_0 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 597.0
PYH3_k127_7545996_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 361.0
PYH3_k127_7545996_2 Acid phosphatase homologues - - - 0.000000003205 60.0
PYH3_k127_7545996_3 PFAM TspO MBR family K05770 - - 0.000000151 52.0
PYH3_k127_763679_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 575.0
PYH3_k127_763679_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 417.0
PYH3_k127_763679_2 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 327.0
PYH3_k127_763679_3 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000009222 221.0
PYH3_k127_763679_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001634 218.0
PYH3_k127_763679_5 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000002487 207.0
PYH3_k127_763679_6 - - - - 0.00000000000000000000000000000006622 128.0
PYH3_k127_763679_7 SNARE associated Golgi protein - - - 0.0000002859 51.0
PYH3_k127_7637104_0 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000001852 196.0
PYH3_k127_7637104_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000004969 136.0
PYH3_k127_7637104_2 PFAM CHAD domain containing protein - - - 0.00000000000007088 79.0
PYH3_k127_7651427_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 539.0
PYH3_k127_7651427_1 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000000001185 164.0
PYH3_k127_7651427_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000007346 127.0
PYH3_k127_7651427_3 Belongs to the UPF0178 family K09768 - - 0.000000000001703 69.0
PYH3_k127_7651427_4 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000003462 50.0
PYH3_k127_7651427_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000009598 50.0
PYH3_k127_7656974_0 receptor K02014 - - 1.574e-320 1006.0
PYH3_k127_7656974_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 3.581e-237 746.0
PYH3_k127_7656974_10 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
PYH3_k127_7656974_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002939 271.0
PYH3_k127_7656974_12 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
PYH3_k127_7656974_13 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000003767 208.0
PYH3_k127_7656974_14 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000005286 215.0
PYH3_k127_7656974_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000006194 204.0
PYH3_k127_7656974_16 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000005787 190.0
PYH3_k127_7656974_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000004499 160.0
PYH3_k127_7656974_18 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000005078 129.0
PYH3_k127_7656974_19 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000000000000174 103.0
PYH3_k127_7656974_2 TonB dependent receptor - - - 2.969e-224 728.0
PYH3_k127_7656974_20 - - - - 0.0000000000000000232 87.0
PYH3_k127_7656974_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 614.0
PYH3_k127_7656974_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 565.0
PYH3_k127_7656974_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 531.0
PYH3_k127_7656974_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 469.0
PYH3_k127_7656974_7 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 466.0
PYH3_k127_7656974_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 449.0
PYH3_k127_7656974_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 377.0
PYH3_k127_7674050_0 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 490.0
PYH3_k127_7674050_1 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
PYH3_k127_7674050_2 abc transporter atp-binding protein K05847 - - 0.0000000000000000000000000000000000000000000000005713 190.0
PYH3_k127_7674050_3 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000001256 99.0
PYH3_k127_769037_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1196.0
PYH3_k127_769037_1 helicase superfamily c-terminal domain K03724 - - 0.0 1059.0
PYH3_k127_769037_10 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 584.0
PYH3_k127_769037_11 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 590.0
PYH3_k127_769037_12 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 559.0
PYH3_k127_769037_13 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 517.0
PYH3_k127_769037_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 517.0
PYH3_k127_769037_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 494.0
PYH3_k127_769037_16 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 482.0
PYH3_k127_769037_17 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 471.0
PYH3_k127_769037_18 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 458.0
PYH3_k127_769037_19 alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 453.0
PYH3_k127_769037_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1034.0
PYH3_k127_769037_20 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 451.0
PYH3_k127_769037_21 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 445.0
PYH3_k127_769037_22 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 424.0
PYH3_k127_769037_23 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 395.0
PYH3_k127_769037_24 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
PYH3_k127_769037_25 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
PYH3_k127_769037_26 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 340.0
PYH3_k127_769037_27 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 330.0
PYH3_k127_769037_28 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 315.0
PYH3_k127_769037_29 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 306.0
PYH3_k127_769037_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.4e-323 996.0
PYH3_k127_769037_30 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 308.0
PYH3_k127_769037_31 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 300.0
PYH3_k127_769037_32 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 287.0
PYH3_k127_769037_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
PYH3_k127_769037_34 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
PYH3_k127_769037_35 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001747 245.0
PYH3_k127_769037_36 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007357 246.0
PYH3_k127_769037_37 Nudix hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000001143 192.0
PYH3_k127_769037_38 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000004079 185.0
PYH3_k127_769037_39 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000009045 179.0
PYH3_k127_769037_4 Elongation factor G, domain IV K02355 - - 6.339e-309 960.0
PYH3_k127_769037_40 Protein of unknown function (DUF1272) - - - 0.0000000000000000000000000000000000001706 142.0
PYH3_k127_769037_41 SWIB/MDM2 domain K03169 - 5.99.1.2 0.000000000000000000000000000000000001808 143.0
PYH3_k127_769037_42 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.0000000000000000000000000000001221 129.0
PYH3_k127_769037_43 Regulatory protein, FmdB family - - - 0.000000000000000000000000000002243 126.0
PYH3_k127_769037_44 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000003827 120.0
PYH3_k127_769037_45 - - - - 0.000000000000000000000000001979 114.0
PYH3_k127_769037_46 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000001115 112.0
PYH3_k127_769037_47 Copper binding periplasmic protein CusF - - - 0.0000000000000004969 83.0
PYH3_k127_769037_48 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000002213 55.0
PYH3_k127_769037_5 ABC transporter transmembrane region K06147,K18893 - - 8.233e-288 904.0
PYH3_k127_769037_6 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 6.637e-241 754.0
PYH3_k127_769037_7 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 1.409e-229 722.0
PYH3_k127_769037_8 Aldehyde dehydrogenase family - - - 4.427e-215 675.0
PYH3_k127_769037_9 B12 binding domain - - - 2.035e-207 660.0
PYH3_k127_7693581_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 342.0
PYH3_k127_7693581_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 337.0
PYH3_k127_7693581_2 COG0784 FOG CheY-like receiver K11443 - - 0.0000000000000000000000000000001274 130.0
PYH3_k127_7703745_0 AcrB/AcrD/AcrF family - - - 0.0 1620.0
PYH3_k127_7703745_1 ABC-type dipeptide transport system, periplasmic component K02035,K12368 - - 1.902e-291 900.0
PYH3_k127_7703745_10 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 452.0
PYH3_k127_7703745_11 ABC-type dipeptide oligopeptide nickel transport system, permease component K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
PYH3_k127_7703745_12 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 430.0
PYH3_k127_7703745_13 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 420.0
PYH3_k127_7703745_14 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 405.0
PYH3_k127_7703745_15 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 391.0
PYH3_k127_7703745_16 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 359.0
PYH3_k127_7703745_17 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 328.0
PYH3_k127_7703745_18 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 323.0
PYH3_k127_7703745_19 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
PYH3_k127_7703745_2 Belongs to the peptidase S16 family - - - 1.66e-284 896.0
PYH3_k127_7703745_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
PYH3_k127_7703745_21 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000001426 229.0
PYH3_k127_7703745_23 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000009253 158.0
PYH3_k127_7703745_24 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.0000000000000000000000000000000000001684 151.0
PYH3_k127_7703745_25 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000005051 93.0
PYH3_k127_7703745_26 PFAM Transposase IS200 like - - - 0.0000000009741 60.0
PYH3_k127_7703745_27 PFAM UspA - - - 0.0006768 50.0
PYH3_k127_7703745_3 alpha-glucan phosphorylase K00688 - 2.4.1.1 3.067e-249 790.0
PYH3_k127_7703745_4 ABC-type dipeptide oligopeptide nickel transport K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 567.0
PYH3_k127_7703745_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 589.0
PYH3_k127_7703745_6 TAP-like protein K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 541.0
PYH3_k127_7703745_7 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 499.0
PYH3_k127_7703745_8 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 486.0
PYH3_k127_7703745_9 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 457.0
PYH3_k127_7714358_0 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000009851 196.0
PYH3_k127_7714358_1 HemY protein N-terminus K02498 - - 0.00000000000000000002733 94.0
PYH3_k127_7714358_2 Uroporphyrinogen-III synthase K01719,K13543 - 2.1.1.107,4.2.1.75 0.000003217 55.0
PYH3_k127_7735091_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.92e-253 792.0
PYH3_k127_7735091_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000003239 140.0
PYH3_k127_7770996_0 ATPase involved in DNA repair - - - 0.0 1185.0
PYH3_k127_7770996_1 ribosome binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 415.0
PYH3_k127_7777684_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1682.0
PYH3_k127_7777684_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.188e-253 801.0
PYH3_k127_7777684_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000002264 159.0
PYH3_k127_7777684_11 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000000664 159.0
PYH3_k127_7777684_12 - - - - 0.0000000000000000000003642 105.0
PYH3_k127_7777684_13 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000008987 74.0
PYH3_k127_7777684_14 Domain of unknown function (DUF1902) - - - 0.0004888 47.0
PYH3_k127_7777684_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 604.0
PYH3_k127_7777684_3 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 588.0
PYH3_k127_7777684_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 477.0
PYH3_k127_7777684_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 434.0
PYH3_k127_7777684_6 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 324.0
PYH3_k127_7777684_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
PYH3_k127_7777684_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000008915 209.0
PYH3_k127_7777684_9 Protein of unknown function (DUF2459) - - - 0.00000000000000000000000000000000000000000003524 171.0
PYH3_k127_7873227_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1229.0
PYH3_k127_7873227_1 type VI secretion protein K11900 - - 1.286e-284 878.0
PYH3_k127_7873227_10 ImpA, N-terminal, type VI secretion system K11902 - - 0.0000000000000000000000001867 113.0
PYH3_k127_7873227_11 - - - - 0.000000000003407 79.0
PYH3_k127_7873227_2 Type VI secretion protein K11896 - - 1.49e-255 803.0
PYH3_k127_7873227_3 rhs element vgr protein K11904 - - 1.162e-209 661.0
PYH3_k127_7873227_4 type VI secretion protein K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 321.0
PYH3_k127_7873227_5 Virulence protein SciE type K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 315.0
PYH3_k127_7873227_6 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 292.0
PYH3_k127_7873227_7 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000002233 190.0
PYH3_k127_7873227_8 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.00000000000000000000000000000000000000000000000001266 187.0
PYH3_k127_7873227_9 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000144 144.0
PYH3_k127_7920151_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 567.0
PYH3_k127_7920151_1 Soluble lytic murein K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 571.0
PYH3_k127_7920151_2 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000003073 253.0
PYH3_k127_7920151_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000001288 183.0
PYH3_k127_7920151_4 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000003657 128.0
PYH3_k127_7968332_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 396.0
PYH3_k127_7968332_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 338.0
PYH3_k127_7968332_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
PYH3_k127_7968332_3 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
PYH3_k127_7984283_0 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 475.0
PYH3_k127_7984283_1 DJ-1/PfpI family - - - 0.0000000000001032 72.0
PYH3_k127_7988143_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 595.0
PYH3_k127_7988143_1 mechanosensitive ion channel K03442,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 330.0
PYH3_k127_7988143_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 322.0
PYH3_k127_7988143_3 amine dehydrogenase activity - - - 0.000000000000614 72.0
PYH3_k127_8085205_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 436.0
PYH3_k127_8085205_1 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 421.0
PYH3_k127_8085205_2 KorB domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000003973 243.0
PYH3_k127_8085205_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000003322 183.0
PYH3_k127_8085205_4 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000000007649 176.0
PYH3_k127_8085205_5 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000005788 146.0
PYH3_k127_8085205_6 Oxidoreductase activity. It is involved in the biological process described with metabolic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000003874 53.0
PYH3_k127_8096395_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1151.0
PYH3_k127_8096395_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 5.847e-211 667.0
PYH3_k127_8096395_2 PFAM ATPase associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 428.0
PYH3_k127_8096395_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 418.0
PYH3_k127_8096395_4 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 346.0
PYH3_k127_8096395_5 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 295.0
PYH3_k127_8096395_6 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000558 112.0
PYH3_k127_8096395_7 - - - - 0.000000000000000002803 91.0
PYH3_k127_8102887_0 COG4974 Site-specific recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
PYH3_k127_8102887_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 381.0
PYH3_k127_8102887_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 363.0
PYH3_k127_8102887_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001594 265.0
PYH3_k127_8102887_4 Belongs to the 'phage' integrase family - - - 0.0000000653 63.0
PYH3_k127_812421_0 GGDEF domain - - - 2.469e-316 990.0
PYH3_k127_812421_1 GGDEF domain - - - 8.246e-286 904.0
PYH3_k127_812421_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.998e-270 833.0
PYH3_k127_812421_3 Subtilase family - - - 2.873e-247 786.0
PYH3_k127_812421_4 Subtilase family - - - 2.438e-220 703.0
PYH3_k127_812421_5 Subtilase family - - - 2.643e-208 665.0
PYH3_k127_8148279_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 1.044e-224 700.0
PYH3_k127_8148279_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 580.0
PYH3_k127_8148279_10 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000001367 127.0
PYH3_k127_8148279_11 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.00000000000000000001369 95.0
PYH3_k127_8148279_2 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 575.0
PYH3_k127_8148279_3 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 516.0
PYH3_k127_8148279_4 Branched-chain amino acid transport system / permease component K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 516.0
PYH3_k127_8148279_5 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 387.0
PYH3_k127_8148279_6 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 356.0
PYH3_k127_8148279_7 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 340.0
PYH3_k127_8148279_8 ATPases associated with a variety of cellular activities K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 319.0
PYH3_k127_8148279_9 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000302 241.0
PYH3_k127_8157951_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 5.867e-302 946.0
PYH3_k127_8157951_1 Formyl transferase K19640 - - 2.785e-214 685.0
PYH3_k127_8157951_10 transcriptional regulators K03892 - - 0.0000000000000000000000000000000000236 138.0
PYH3_k127_8157951_11 - - - - 0.000000000000000000000000000000000416 147.0
PYH3_k127_8157951_12 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000001977 108.0
PYH3_k127_8157951_13 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000004102 106.0
PYH3_k127_8157951_14 - - - - 0.0000000000000000000008431 102.0
PYH3_k127_8157951_15 Transcriptional regulator K07722 - - 0.000000000007118 67.0
PYH3_k127_8157951_16 Belongs to the HypD family K04654 - - 0.00000002359 59.0
PYH3_k127_8157951_2 Belongs to the HypD family K04654 - - 1.311e-196 621.0
PYH3_k127_8157951_3 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 537.0
PYH3_k127_8157951_4 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 532.0
PYH3_k127_8157951_5 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 408.0
PYH3_k127_8157951_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 308.0
PYH3_k127_8157951_7 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000005626 231.0
PYH3_k127_8157951_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000007813 176.0
PYH3_k127_8157951_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000002151 152.0
PYH3_k127_8172173_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 495.0
PYH3_k127_8172173_1 ErfK YbiS YcfS YnhG family protein K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 424.0
PYH3_k127_8172173_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
PYH3_k127_8172173_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 344.0
PYH3_k127_8172173_4 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
PYH3_k127_8172173_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000736 179.0
PYH3_k127_8172173_6 - - - - 0.000000000002006 79.0
PYH3_k127_8223314_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 344.0
PYH3_k127_8223314_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000133 174.0
PYH3_k127_8223314_2 Histidine kinase K20975 - 2.7.13.3 0.000000000000001477 83.0
PYH3_k127_83131_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 3.733e-263 826.0
PYH3_k127_83131_1 Dehydrogenase K15515 - 1.2.1.81 5.23e-210 661.0
PYH3_k127_83131_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.829e-208 658.0
PYH3_k127_83131_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 490.0
PYH3_k127_83131_4 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000003744 140.0
PYH3_k127_83131_5 Transcriptional regulator IclR - - - 0.0000000000000000001802 94.0
PYH3_k127_83131_6 Tripartite tricarboxylate transporter family receptor - - - 0.000002675 49.0
PYH3_k127_83512_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1053.0
PYH3_k127_83512_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 493.0
PYH3_k127_83512_2 PFAM Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000000000003321 153.0
PYH3_k127_83512_3 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000000000000000000000000000003552 143.0
PYH3_k127_83512_4 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000001793 131.0
PYH3_k127_83512_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000004955 111.0
PYH3_k127_83512_6 - - - - 0.000000000000002254 85.0
PYH3_k127_8369437_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 538.0
PYH3_k127_8369437_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 511.0
PYH3_k127_8369437_10 Ferredoxin - - - 0.000000000000000000000000000000000000000000001854 166.0
PYH3_k127_8369437_11 BON domain - - - 0.0000000000000000000000000000000000000000002138 169.0
PYH3_k127_8369437_12 Thioredoxin-like - - - 0.000000000000000000000000000000000000000003178 171.0
PYH3_k127_8369437_13 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000001256 161.0
PYH3_k127_8369437_14 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000004894 145.0
PYH3_k127_8369437_15 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000004871 124.0
PYH3_k127_8369437_16 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000001395 124.0
PYH3_k127_8369437_17 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000002969 122.0
PYH3_k127_8369437_18 LppC putative lipoprotein K07121 - - 0.000000000000000000000008872 107.0
PYH3_k127_8369437_19 Sporulation domain protein - - - 0.000000000000008188 83.0
PYH3_k127_8369437_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 385.0
PYH3_k127_8369437_20 - - - - 0.000000000002879 74.0
PYH3_k127_8369437_3 PFAM aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 311.0
PYH3_k127_8369437_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
PYH3_k127_8369437_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001345 272.0
PYH3_k127_8369437_6 PFAM VanZ family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005641 282.0
PYH3_k127_8369437_7 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 269.0
PYH3_k127_8369437_8 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000001801 240.0
PYH3_k127_8369437_9 HIT domain - - - 0.00000000000000000000000000000000000000000000003007 179.0
PYH3_k127_8411102_0 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 427.0
PYH3_k127_8411102_1 GAF domain K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 380.0
PYH3_k127_8411102_2 ABC-2 family transporter protein K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 300.0
PYH3_k127_8411102_3 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 287.0
PYH3_k127_8411102_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
PYH3_k127_8411102_5 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002293 244.0
PYH3_k127_8411102_6 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007353 247.0
PYH3_k127_8411102_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000001476 168.0
PYH3_k127_8411102_8 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000007038 121.0
PYH3_k127_8411102_9 PFAM Major facilitator superfamily K02575 - - 0.00000000000000001431 85.0
PYH3_k127_8420143_0 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 9.53e-246 774.0
PYH3_k127_8420143_1 Predicted membrane protein (DUF2339) - - - 3.284e-208 688.0
PYH3_k127_8420143_10 Domain of unknown function (DUF3597) - - - 0.00001663 51.0
PYH3_k127_8420143_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 453.0
PYH3_k127_8420143_3 hydrolase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 336.0
PYH3_k127_8420143_4 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 319.0
PYH3_k127_8420143_5 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
PYH3_k127_8420143_6 FAD dependent oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000002021 247.0
PYH3_k127_8420143_7 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005739 227.0
PYH3_k127_8420143_8 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000008763 198.0
PYH3_k127_8420143_9 Pilin (bacterial filament) K02650 - - 0.000006541 53.0
PYH3_k127_8421385_0 Elements of external origin K07494 - - 1.116e-208 652.0
PYH3_k127_8421385_1 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 301.0
PYH3_k127_8567035_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 416.0
PYH3_k127_8567035_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
PYH3_k127_8567035_2 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000001187 118.0
PYH3_k127_8567035_3 receptor K16087 - - 0.0000000000000000000001491 103.0
PYH3_k127_8567035_4 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000123 86.0
PYH3_k127_8611838_0 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000108 269.0
PYH3_k127_8611838_1 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000233 224.0
PYH3_k127_8611838_2 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000001103 160.0
PYH3_k127_8611838_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000008114 111.0
PYH3_k127_8611838_4 Histidine kinase - - - 0.0000000000000000000001394 100.0
PYH3_k127_8644812_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1277.0
PYH3_k127_8644812_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
PYH3_k127_8644812_2 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
PYH3_k127_8644812_3 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
PYH3_k127_8644812_4 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000004889 187.0
PYH3_k127_8644812_5 - - - - 0.0000000000000000000000000000000000000000000004654 171.0
PYH3_k127_8644812_6 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000000209 170.0
PYH3_k127_8644812_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000003839 126.0
PYH3_k127_8644812_8 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000228 123.0
PYH3_k127_8644812_9 - - - - 0.000000000000000000000005006 105.0
PYH3_k127_8651699_0 Multicopper oxidase - - - 1.785e-218 684.0
PYH3_k127_8651699_1 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000005502 161.0
PYH3_k127_8651699_2 Copper binding periplasmic protein CusF - - - 0.0000000000000000000003783 101.0
PYH3_k127_8654388_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.711e-207 651.0
PYH3_k127_8654388_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 573.0
PYH3_k127_8654388_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000001595 62.0
PYH3_k127_8654388_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 552.0
PYH3_k127_8654388_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 541.0
PYH3_k127_8654388_4 3-5 exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
PYH3_k127_8654388_5 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 312.0
PYH3_k127_8654388_6 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 237.0
PYH3_k127_8654388_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001062 234.0
PYH3_k127_8654388_8 Tetratricopeptide repeat K02656 - - 0.00000000000000000000000000000000000000000000000000000000003396 220.0
PYH3_k127_8654388_9 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000002202 126.0
PYH3_k127_8655373_0 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 426.0
PYH3_k127_8655373_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000004288 198.0
PYH3_k127_8655373_2 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000005094 74.0
PYH3_k127_8675963_0 chaperone-mediated protein folding K12132 - 2.7.11.1 1.065e-266 851.0
PYH3_k127_8736502_0 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000000004804 224.0
PYH3_k127_8736502_1 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000004107 168.0
PYH3_k127_8736502_2 mRNA binding K07339 - - 0.00000000000001215 85.0
PYH3_k127_8736502_3 Glyoxalase-like domain - - - 0.00000013 53.0
PYH3_k127_8756455_0 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 1.345e-216 685.0
PYH3_k127_8756455_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 381.0
PYH3_k127_8756455_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008978 264.0
PYH3_k127_8756455_3 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
PYH3_k127_8756455_4 DNA integration - - - 0.000002465 49.0
PYH3_k127_8785437_0 fad dependent oxidoreductase K07137 - - 6.698e-288 894.0
PYH3_k127_8785437_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.747e-253 804.0
PYH3_k127_8785437_10 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000762 192.0
PYH3_k127_8785437_11 Branched-chain amino acid permease - - - 0.0000000000000000000000000000000000000000000000000005268 207.0
PYH3_k127_8785437_12 - - - - 0.00000000000000000000000000000000001617 143.0
PYH3_k127_8785437_13 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000004259 136.0
PYH3_k127_8785437_14 SnoaL-like domain - - - 0.000000000000000000000000000000501 127.0
PYH3_k127_8785437_15 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000209 117.0
PYH3_k127_8785437_16 Methyltransferase domain - - - 0.00000000000000000000002047 103.0
PYH3_k127_8785437_17 Zinc-finger domain - - - 0.00000000000000000000002136 103.0
PYH3_k127_8785437_18 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000002039 103.0
PYH3_k127_8785437_19 - - - - 0.0000000000000000000004135 103.0
PYH3_k127_8785437_2 4Fe-4S dicluster domain - - - 7.531e-246 769.0
PYH3_k127_8785437_20 FAD linked oxidases, C-terminal domain K18930 - - 0.00000000002627 67.0
PYH3_k127_8785437_21 Lipase class 3 family protein - - - 0.0004385 53.0
PYH3_k127_8785437_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 578.0
PYH3_k127_8785437_4 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 546.0
PYH3_k127_8785437_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 499.0
PYH3_k127_8785437_6 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 398.0
PYH3_k127_8785437_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 364.0
PYH3_k127_8785437_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
PYH3_k127_8785437_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
PYH3_k127_889167_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.568e-276 860.0
PYH3_k127_889167_1 PFAM Peptidase family M20 M25 M40, Peptidase dimerization domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 550.0
PYH3_k127_889167_2 Transketolase, C-terminal domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 492.0
PYH3_k127_889167_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 464.0
PYH3_k127_889167_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000009634 225.0
PYH3_k127_889167_5 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000004474 166.0
PYH3_k127_889167_6 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000005552 138.0
PYH3_k127_889167_7 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000001274 134.0
PYH3_k127_889167_8 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000906 129.0
PYH3_k127_889167_9 FMN binding - - - 0.0000000000000000000000000002022 124.0
PYH3_k127_8923027_0 Dynamin family - - - 2.917e-195 630.0
PYH3_k127_8923027_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 577.0
PYH3_k127_8923027_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004618 273.0
PYH3_k127_8923027_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000001795 242.0
PYH3_k127_8923027_12 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
PYH3_k127_8923027_13 PFAM peptidase S16 lon domain protein K07157 - - 0.0000000000000000000000000000000000000000000000000000001406 203.0
PYH3_k127_8923027_14 PFAM PsiF repeat protein - - - 0.000000000000000000005085 96.0
PYH3_k127_8923027_15 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000002016 98.0
PYH3_k127_8923027_16 Acetyltransferase (GNAT) family - - - 0.00000000007725 64.0
PYH3_k127_8923027_17 - - - - 0.0009645 43.0
PYH3_k127_8923027_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 523.0
PYH3_k127_8923027_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 429.0
PYH3_k127_8923027_4 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 386.0
PYH3_k127_8923027_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 377.0
PYH3_k127_8923027_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 340.0
PYH3_k127_8923027_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 333.0
PYH3_k127_8923027_8 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 324.0
PYH3_k127_8923027_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
PYH3_k127_8964944_0 Tetratricopeptide repeat - - - 2.141e-231 733.0
PYH3_k127_8964944_1 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 481.0
PYH3_k127_8964944_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001068 279.0
PYH3_k127_8964944_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000006346 219.0
PYH3_k127_898224_0 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 541.0
PYH3_k127_898224_1 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 517.0
PYH3_k127_898224_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 300.0
PYH3_k127_898224_11 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 299.0
PYH3_k127_898224_12 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 301.0
PYH3_k127_898224_13 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 258.0
PYH3_k127_898224_14 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000009361 230.0
PYH3_k127_898224_15 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000005613 201.0
PYH3_k127_898224_16 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000001057 190.0
PYH3_k127_898224_17 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000003089 177.0
PYH3_k127_898224_18 Chalcone isomerase-like - - - 0.000000000000000000000000000000000002428 147.0
PYH3_k127_898224_19 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000001561 128.0
PYH3_k127_898224_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 501.0
PYH3_k127_898224_20 - - - - 0.000000000000000000000000004372 119.0
PYH3_k127_898224_21 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000003094 109.0
PYH3_k127_898224_22 Protein of unknown function (DUF3108) - - - 0.0000000000000000006108 95.0
PYH3_k127_898224_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 476.0
PYH3_k127_898224_4 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 398.0
PYH3_k127_898224_5 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
PYH3_k127_898224_6 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 335.0
PYH3_k127_898224_7 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 333.0
PYH3_k127_898224_8 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
PYH3_k127_898224_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 309.0
PYH3_k127_9055823_0 DNA polymerase III K02342 - 2.7.7.7 1.792e-253 794.0
PYH3_k127_9055823_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 554.0
PYH3_k127_9055823_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 389.0
PYH3_k127_9055823_3 Nad-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 336.0
PYH3_k127_9055823_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000003159 222.0
PYH3_k127_9055823_5 Protein of unknown function (DUF2905) - - - 0.0000000000000000883 85.0
PYH3_k127_9074179_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 432.0
PYH3_k127_9074179_1 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 373.0
PYH3_k127_9074179_2 NAD(FAD)-dependent dehydrogenase - - - 0.000000000000000000000000004885 113.0
PYH3_k127_9074179_3 ABC transporter permease K02053 - - 0.000000000000000000002035 94.0
PYH3_k127_9094057_0 Malic enzyme K00029 - 1.1.1.40 0.0 1080.0
PYH3_k127_9094057_1 Phosphoesterase family - - - 1.204e-198 631.0
PYH3_k127_9094057_2 aldo keto reductase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
PYH3_k127_9094057_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 363.0
PYH3_k127_9094057_4 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21607 - 1.1.1.404 0.00000000000000000000000000000000000000000000000000000000000000000001118 245.0
PYH3_k127_9094057_5 Related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001392 243.0
PYH3_k127_9094057_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008029 224.0
PYH3_k127_9094057_7 Acyl dehydratase - - - 0.00000000000000000000000000000000000000003174 158.0
PYH3_k127_9094057_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001876 146.0
PYH3_k127_9094057_9 signal peptide protein - - - 0.000007835 51.0
PYH3_k127_9175710_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1064.0
PYH3_k127_9222979_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 4.977e-244 769.0
PYH3_k127_9222979_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.785e-240 752.0
PYH3_k127_9222979_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 1.846e-224 706.0
PYH3_k127_9222979_3 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 560.0
PYH3_k127_9222979_4 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 549.0
PYH3_k127_9248854_0 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 460.0
PYH3_k127_9248854_1 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 398.0
PYH3_k127_9248854_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 287.0
PYH3_k127_9248854_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000001129 246.0
PYH3_k127_9248854_4 - - - - 0.000000000000000000000000001908 118.0
PYH3_k127_9268971_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 460.0
PYH3_k127_9268971_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 343.0
PYH3_k127_9281656_0 DNA integration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 555.0
PYH3_k127_9281656_1 Domain of unknown function (DUF927) K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 313.0
PYH3_k127_9281656_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000304 184.0
PYH3_k127_9281656_3 Multicopper oxidase - - - 0.000000000000000000000000000000000000516 156.0
PYH3_k127_9281656_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000004468 137.0
PYH3_k127_9281656_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000002171 106.0
PYH3_k127_9281656_6 - - - - 0.00000001397 59.0
PYH3_k127_9281656_7 - - - - 0.000001302 55.0
PYH3_k127_9281656_8 - - - - 0.0001187 48.0
PYH3_k127_9281656_9 Belongs to the isocitrate lyase PEP mutase superfamily. Methylisocitrate lyase family - - - 0.0001843 46.0
PYH3_k127_9304790_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
PYH3_k127_9304790_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000004431 99.0
PYH3_k127_9304790_2 Helix-turn-helix domain - - - 0.000000000000000000002285 94.0
PYH3_k127_9372330_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 377.0
PYH3_k127_9372330_1 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008854 282.0
PYH3_k127_9372330_2 aminopeptidase N K01256 - 3.4.11.2 0.00000000000000000000000000000000000000006718 154.0
PYH3_k127_9372330_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000005395 112.0
PYH3_k127_9384671_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 569.0
PYH3_k127_9384671_1 - - - - 0.0000000000000000000000000002161 117.0
PYH3_k127_9384671_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000003311 63.0
PYH3_k127_9396052_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 5.46e-307 977.0
PYH3_k127_9396052_1 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 469.0
PYH3_k127_9396052_10 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000000000004826 213.0
PYH3_k127_9396052_11 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000000007671 154.0
PYH3_k127_9396052_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.0000000000000000000000000000000173 143.0
PYH3_k127_9396052_13 Na+/H+ antiporter subunit K05564,K05571 - - 0.00000000000000000000000000002089 124.0
PYH3_k127_9396052_14 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.000000000000000000000003131 105.0
PYH3_k127_9396052_15 - - - - 0.00000000000004108 79.0
PYH3_k127_9396052_16 Protein of unknown function (DUF2934) - - - 0.0000004409 57.0
PYH3_k127_9396052_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 451.0
PYH3_k127_9396052_3 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 404.0
PYH3_k127_9396052_4 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
PYH3_k127_9396052_5 Membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 346.0
PYH3_k127_9396052_6 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 326.0
PYH3_k127_9396052_7 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 285.0
PYH3_k127_9396052_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000003665 232.0
PYH3_k127_9396052_9 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000003014 235.0
PYH3_k127_9415471_0 Acyl-CoA dehydrogenase, middle domain - - - 3.617e-212 664.0
PYH3_k127_9415471_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 588.0
PYH3_k127_9415471_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000008714 215.0
PYH3_k127_9415471_3 GYD domain - - - 0.000000000000000000000000000000525 124.0
PYH3_k127_9415471_4 Transcriptional regulator - - - 0.000000000000277 69.0
PYH3_k127_9415471_5 Zinc-binding dehydrogenase - - - 0.00002396 52.0
PYH3_k127_9415471_7 Protein of unknown function (DUF3617) - - - 0.00006445 51.0
PYH3_k127_9415471_8 Tripartite tricarboxylate transporter family receptor - - - 0.0006689 46.0
PYH3_k127_9427258_0 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000003293 164.0
PYH3_k127_9427258_1 - - - - 0.000000000000003992 76.0
PYH3_k127_9454220_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1335.0
PYH3_k127_9454220_1 Domain of unknown function (DUF4393) - - - 0.0000000000000000000000000000000000000000000000000000002571 203.0
PYH3_k127_9454220_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000001481 112.0
PYH3_k127_9454220_3 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000004543 100.0
PYH3_k127_9454220_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000006655 76.0
PYH3_k127_9454220_5 Plasmid stabilization system K19092 GO:0002790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030255,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0043684,GO:0044097,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0097159,GO:1901363 - 0.000215 44.0
PYH3_k127_9468690_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 500.0
PYH3_k127_9468690_1 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 424.0
PYH3_k127_9468690_10 competence protein COMEC - - - 0.000000000000000005853 94.0
PYH3_k127_9468690_11 competence protein COMEC - - - 0.000000001077 69.0
PYH3_k127_9468690_12 extracellular polysaccharide biosynthetic process K16554 - - 0.00000004705 55.0
PYH3_k127_9468690_13 Psort location Cytoplasmic, score - - - 0.0009344 46.0
PYH3_k127_9468690_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 428.0
PYH3_k127_9468690_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 341.0
PYH3_k127_9468690_4 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000253 274.0
PYH3_k127_9468690_5 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002854 251.0
PYH3_k127_9468690_6 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000001405 222.0
PYH3_k127_9468690_7 GDYXXLXY protein - - - 0.0000000000000000000000000000000000000000000000000000000001075 224.0
PYH3_k127_9468690_8 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000000001377 96.0
PYH3_k127_9468690_9 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000002981 92.0
PYH3_k127_9504140_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
PYH3_k127_9504140_1 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000002303 180.0
PYH3_k127_9504140_2 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000001126 117.0
PYH3_k127_9504140_3 pyridoxamine 5-phosphate - - - 0.000000000000000000000005176 107.0
PYH3_k127_9552232_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 513.0
PYH3_k127_9552232_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 487.0
PYH3_k127_9552232_10 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000005181 198.0
PYH3_k127_9552232_11 PFAM Negative transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000006672 179.0
PYH3_k127_9552232_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001255 166.0
PYH3_k127_9552232_14 Nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000002443 151.0
PYH3_k127_9552232_15 replication factor c K16247 - - 0.00000000000000000000000004994 111.0
PYH3_k127_9552232_16 - - - - 0.0000000000004199 80.0
PYH3_k127_9552232_17 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000002261 66.0
PYH3_k127_9552232_18 Pkd domain containing protein - - - 0.00000003508 60.0
PYH3_k127_9552232_19 Phage capsid family - - - 0.000002107 59.0
PYH3_k127_9552232_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 376.0
PYH3_k127_9552232_3 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 353.0
PYH3_k127_9552232_4 Protein of unknown function (DUF3631) K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 366.0
PYH3_k127_9552232_5 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 346.0
PYH3_k127_9552232_6 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 334.0
PYH3_k127_9552232_7 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 324.0
PYH3_k127_9552232_8 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008038 269.0
PYH3_k127_9552232_9 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001377 237.0
PYH3_k127_9583932_0 Peptidase C39 family K13409 - - 5.43e-203 653.0
PYH3_k127_9583932_1 transposase IS116 IS110 IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 546.0
PYH3_k127_9583932_2 Lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 448.0
PYH3_k127_9583932_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 408.0
PYH3_k127_9583932_4 reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 409.0
PYH3_k127_9583932_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 291.0
PYH3_k127_9583932_6 HlyD family secretion protein K13408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004388 265.0
PYH3_k127_9583932_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001325 226.0
PYH3_k127_958583_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 328.0
PYH3_k127_958583_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000001602 139.0
PYH3_k127_958583_2 PFAM cytochrome c - - - 0.0000000000000000413 82.0
PYH3_k127_9588700_0 ankyrin repeats - - - 1.579e-257 813.0
PYH3_k127_9588700_1 Phosphoglucomutase K01835 - 5.4.2.2 4.536e-252 786.0
PYH3_k127_9588700_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.109e-203 640.0
PYH3_k127_9588700_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 528.0
PYH3_k127_9588700_4 ATPases associated with a variety of cellular activities K10112 - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
PYH3_k127_9588700_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000008333 153.0
PYH3_k127_9588700_6 - - - - 0.0000000000000000000000000005645 118.0
PYH3_k127_9588700_7 Helix-turn-helix domain - - - 0.000000000000003747 77.0
PYH3_k127_9589500_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.338e-242 766.0
PYH3_k127_9589500_1 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 4.173e-222 701.0
PYH3_k127_9589500_10 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000001876 173.0
PYH3_k127_9589500_11 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000002656 137.0
PYH3_k127_9589500_12 cellulase activity - - - 0.0000000000000000000002105 112.0
PYH3_k127_9589500_13 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000001293 97.0
PYH3_k127_9589500_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 580.0
PYH3_k127_9589500_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 433.0
PYH3_k127_9589500_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 351.0
PYH3_k127_9589500_5 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
PYH3_k127_9589500_6 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
PYH3_k127_9589500_7 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000009541 243.0
PYH3_k127_9589500_8 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000006097 181.0
PYH3_k127_9589500_9 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000147 179.0
PYH3_k127_9648009_0 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 340.0
PYH3_k127_9648009_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000001904 204.0
PYH3_k127_9648009_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000008755 113.0
PYH3_k127_9648009_3 part of a sulfur-relay system K11179 - - 0.0000000000000000000002483 98.0
PYH3_k127_9648009_4 - - - - 0.00000000000000000001459 98.0
PYH3_k127_9648009_5 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000002042 64.0
PYH3_k127_9648009_6 - - - - 0.000003529 51.0
PYH3_k127_9649053_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 464.0
PYH3_k127_9649053_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 317.0
PYH3_k127_9649053_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 290.0
PYH3_k127_9649053_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004386 255.0
PYH3_k127_9649053_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000004088 177.0
PYH3_k127_9649053_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000003636 167.0
PYH3_k127_9649053_6 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000114 126.0
PYH3_k127_9649053_7 protein conserved in bacteria - - - 0.00000000000000000000000145 115.0
PYH3_k127_9700107_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.354e-247 781.0
PYH3_k127_9700107_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 546.0
PYH3_k127_9700107_10 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000007942 117.0
PYH3_k127_9700107_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 419.0
PYH3_k127_9700107_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 377.0
PYH3_k127_9700107_4 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 376.0
PYH3_k127_9700107_5 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000008343 225.0
PYH3_k127_9700107_6 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000001358 192.0
PYH3_k127_9700107_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000004819 156.0
PYH3_k127_9700107_8 sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000002354 131.0
PYH3_k127_9700107_9 Histidine kinase - - - 0.0000000000000000000000000000001208 129.0
PYH3_k127_9733342_0 Rad50 zinc hook motif K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 345.0
PYH3_k127_9733342_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000002342 119.0
PYH3_k127_9745306_0 COG0457 FOG TPR repeat - - - 3.422e-215 681.0
PYH3_k127_9745306_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 552.0
PYH3_k127_9745306_10 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
PYH3_k127_9745306_11 Cupin domain - - - 0.00000000000000000000000000000000000000000000001868 178.0
PYH3_k127_9745306_12 TIGRFAM DnaA regulatory inactivator Hda K10763 - - 0.000000000000000000000000000000000000000000000401 184.0
PYH3_k127_9745306_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000005194 166.0
PYH3_k127_9745306_14 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000613 166.0
PYH3_k127_9745306_15 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000005089 154.0
PYH3_k127_9745306_16 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000003765 116.0
PYH3_k127_9745306_17 DsrE/DsrF-like family K09004 - - 0.0000000000000000000001146 104.0
PYH3_k127_9745306_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 535.0
PYH3_k127_9745306_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 492.0
PYH3_k127_9745306_4 Patatin phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 466.0
PYH3_k127_9745306_5 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 463.0
PYH3_k127_9745306_6 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 347.0
PYH3_k127_9745306_7 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 332.0
PYH3_k127_9745306_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 308.0
PYH3_k127_9745306_9 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 291.0