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Overview

ID MAG03249
Name PYH3_bin.60
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family CSP1-6
Genus AR37
Species
Assembly information
Completeness (%) 78.13
Contamination (%) 2.65
GC content (%) 68.0
N50 (bp) 11,280
Genome size (bp) 3,102,157

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3090

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1025618_0 Adenylate and Guanylate cyclase catalytic domain - - - 6.606e-318 1008.0
PYH3_k127_1025618_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000004004 205.0
PYH3_k127_1025618_2 HAMP domain - - - 0.000000000000000000000000000000000000000000000000003402 192.0
PYH3_k127_1025618_3 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000004732 121.0
PYH3_k127_1025618_4 - - - - 0.000000006504 67.0
PYH3_k127_1035197_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1017.0
PYH3_k127_1035197_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.577e-291 911.0
PYH3_k127_1035197_10 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 292.0
PYH3_k127_1035197_11 Cell division protein ZipA - - - 0.000000000000000000000000000000000000000000000000000000000006989 212.0
PYH3_k127_1035197_12 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000001939 220.0
PYH3_k127_1035197_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000004087 218.0
PYH3_k127_1035197_14 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000603 186.0
PYH3_k127_1035197_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000001311 168.0
PYH3_k127_1035197_16 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000000001027 151.0
PYH3_k127_1035197_17 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.0000000000000000000000000000000000005797 157.0
PYH3_k127_1035197_18 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000002394 130.0
PYH3_k127_1035197_19 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000002076 126.0
PYH3_k127_1035197_2 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 1.145e-236 747.0
PYH3_k127_1035197_20 Domain of unknown function DUF302 - - - 0.000000000000000000000003522 107.0
PYH3_k127_1035197_21 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000004872 96.0
PYH3_k127_1035197_22 Protein of unknown function (DUF2905) - - - 0.0000000000000000008138 97.0
PYH3_k127_1035197_23 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000002745 85.0
PYH3_k127_1035197_24 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000002934 82.0
PYH3_k127_1035197_3 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 591.0
PYH3_k127_1035197_4 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 576.0
PYH3_k127_1035197_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 507.0
PYH3_k127_1035197_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 392.0
PYH3_k127_1035197_7 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 399.0
PYH3_k127_1035197_8 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
PYH3_k127_1035197_9 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 298.0
PYH3_k127_1088155_0 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002356 250.0
PYH3_k127_1088155_1 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000002233 252.0
PYH3_k127_1088155_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000001634 213.0
PYH3_k127_1088155_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000002371 153.0
PYH3_k127_1088155_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000006005 148.0
PYH3_k127_1088155_5 - - - - 0.0000000000000000000000000000001709 140.0
PYH3_k127_1088155_6 rRNA (guanine-N2-)-methyltransferase activity - - - 0.000000000000000003374 93.0
PYH3_k127_1088155_7 Cytochrome c K00406,K08906 - - 0.0000000000354 75.0
PYH3_k127_1111303_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.861e-268 840.0
PYH3_k127_1111303_1 Amidohydrolase family K01466 - 3.5.2.5 2.518e-215 692.0
PYH3_k127_1111303_10 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000002473 206.0
PYH3_k127_1111303_11 PFAM binding-protein-dependent transport systems inner membrane component K15554 - - 0.000000000000000000000000000000000000000000000000000001361 205.0
PYH3_k127_1111303_12 PFAM Xanthine uracil vitamin C permease K06901 - - 0.0000000000000000000000000000000000000000000000001292 180.0
PYH3_k127_1111303_13 NMT1-like family - - - 0.0000000000000000000000000000000000000000000001191 189.0
PYH3_k127_1111303_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000001077 173.0
PYH3_k127_1111303_15 Domain of unknown function (DUF4387) - - - 0.0000000000000000000000000009582 115.0
PYH3_k127_1111303_16 DNA-sulfur modification-associated - - - 0.000000000000000006951 96.0
PYH3_k127_1111303_17 SnoaL-like domain - - - 0.0000478 49.0
PYH3_k127_1111303_2 GMC oxidoreductase K00108 - 1.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 543.0
PYH3_k127_1111303_3 Pfam:DUF1446 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 510.0
PYH3_k127_1111303_4 Dihydropyrimidinase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 315.0
PYH3_k127_1111303_5 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 314.0
PYH3_k127_1111303_6 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002177 294.0
PYH3_k127_1111303_7 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000006644 265.0
PYH3_k127_1111303_8 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000002009 265.0
PYH3_k127_1111303_9 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000003188 214.0
PYH3_k127_1146173_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 497.0
PYH3_k127_1146173_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 441.0
PYH3_k127_1146173_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
PYH3_k127_1146173_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 383.0
PYH3_k127_1146173_4 - - - - 0.000000000000000000000000000000000000000000000000000000005 207.0
PYH3_k127_1146173_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000215 209.0
PYH3_k127_1146173_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000004119 175.0
PYH3_k127_1167595_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 360.0
PYH3_k127_1167595_1 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 344.0
PYH3_k127_1167595_10 oxidation-reduction process - - - 0.00000000000000000000000000000000837 132.0
PYH3_k127_1167595_11 Protein of unknown function, DUF488 - - - 0.0000000000000003264 87.0
PYH3_k127_1167595_12 Contains selenocysteine K07401 - - 0.00001506 49.0
PYH3_k127_1167595_2 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 323.0
PYH3_k127_1167595_3 ribosylpyrimidine nucleosidase activity K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 308.0
PYH3_k127_1167595_4 D-amino-acid K18482 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 304.0
PYH3_k127_1167595_5 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000007115 274.0
PYH3_k127_1167595_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006464 268.0
PYH3_k127_1167595_7 TIGRFAM membrane complex biogenesis protein, BtpA family K06971 - - 0.000000000000000000000000000000000000000000000006519 177.0
PYH3_k127_1167595_8 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000009086 164.0
PYH3_k127_1167595_9 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000001799 151.0
PYH3_k127_117840_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 459.0
PYH3_k127_117840_1 AMP-binding enzyme K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 408.0
PYH3_k127_117840_10 metallo-beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000884 211.0
PYH3_k127_117840_11 Thioesterase superfamily K01075 - 3.1.2.23 0.00000000000000000000000008366 111.0
PYH3_k127_117840_12 - - - - 0.0000000000000000001643 97.0
PYH3_k127_117840_13 - - - - 0.0000000002271 70.0
PYH3_k127_117840_2 Ethanolamine utilization protein EutJ K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 328.0
PYH3_k127_117840_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 297.0
PYH3_k127_117840_4 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003823 265.0
PYH3_k127_117840_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002811 263.0
PYH3_k127_117840_6 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000003903 222.0
PYH3_k127_117840_7 PFAM SNF2-related protein K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001861 212.0
PYH3_k127_117840_8 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000002522 210.0
PYH3_k127_117840_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000000000000000000005255 213.0
PYH3_k127_1223265_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.169e-204 648.0
PYH3_k127_1223265_1 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000002125 145.0
PYH3_k127_1223265_2 Radical SAM - - - 0.000000000000000000000002424 110.0
PYH3_k127_1223265_3 response regulator K02481 - - 0.0000000000000001189 89.0
PYH3_k127_1267144_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 419.0
PYH3_k127_1267144_1 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004381 258.0
PYH3_k127_1267144_2 - - - - 0.000000000000000000004837 100.0
PYH3_k127_1273854_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1122.0
PYH3_k127_1273854_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.156e-213 685.0
PYH3_k127_1273854_2 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 474.0
PYH3_k127_1273854_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 432.0
PYH3_k127_1273854_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
PYH3_k127_1273854_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000003529 133.0
PYH3_k127_1273854_6 oligosaccharyl transferase activity - - - 0.000008367 57.0
PYH3_k127_1273854_7 gag-polyprotein putative aspartyl protease - - - 0.00003043 55.0
PYH3_k127_1275599_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 488.0
PYH3_k127_1275599_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 314.0
PYH3_k127_1275599_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000003264 107.0
PYH3_k127_1299067_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 6.729e-200 641.0
PYH3_k127_1299067_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 602.0
PYH3_k127_1299067_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 430.0
PYH3_k127_1299067_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 384.0
PYH3_k127_1299067_4 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 286.0
PYH3_k127_1322297_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 476.0
PYH3_k127_1322297_1 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 434.0
PYH3_k127_1322297_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000606 256.0
PYH3_k127_1322297_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000002036 225.0
PYH3_k127_1322297_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000001737 207.0
PYH3_k127_1322297_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000006563 216.0
PYH3_k127_1322297_6 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000564 165.0
PYH3_k127_1322297_7 - - - - 0.0000000001624 67.0
PYH3_k127_1362567_0 Rieske 2Fe-2S domain protein K16319,K18074,K18242 - 1.14.12.1,1.14.12.15,1.14.13.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 541.0
PYH3_k127_1362567_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 506.0
PYH3_k127_1362567_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000008259 168.0
PYH3_k127_1362567_11 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000001238 145.0
PYH3_k127_1362567_12 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000002637 131.0
PYH3_k127_1362567_14 Sporulation related domain - - - 0.0004623 46.0
PYH3_k127_1362567_2 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 337.0
PYH3_k127_1362567_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 314.0
PYH3_k127_1362567_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02032,K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 310.0
PYH3_k127_1362567_5 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000007982 254.0
PYH3_k127_1362567_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000001088 234.0
PYH3_k127_1362567_7 Ring hydroxylating beta subunit K18075 - 1.14.12.15 0.00000000000000000000000000000000000000000000000001108 186.0
PYH3_k127_1362567_8 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000001847 181.0
PYH3_k127_1362567_9 PFAM RES domain - - - 0.000000000000000000000000000000000000000000002274 168.0
PYH3_k127_1373367_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 594.0
PYH3_k127_1373367_1 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 481.0
PYH3_k127_1373367_2 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 423.0
PYH3_k127_1373367_3 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
PYH3_k127_1373367_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001591 294.0
PYH3_k127_1373367_5 TIGRFAM MoaD family protein K03636 - - 0.0000000000000000000000000000000003502 133.0
PYH3_k127_1373367_6 NIL - - - 0.0000000000000005843 85.0
PYH3_k127_1375411_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 326.0
PYH3_k127_1375411_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 294.0
PYH3_k127_1375411_2 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000603 274.0
PYH3_k127_1375411_3 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000008012 153.0
PYH3_k127_1375411_4 DoxX K15977 - - 0.0000000000000000000000000000000000001486 148.0
PYH3_k127_1375411_5 - - - - 0.000000000000000000000000002073 116.0
PYH3_k127_1375411_6 PFAM extracellular solute-binding protein family 5 K02035,K13889 - - 0.000000000000001413 80.0
PYH3_k127_1375411_7 - - - - 0.000001012 54.0
PYH3_k127_1375411_8 OsmC-like protein - - - 0.000001894 53.0
PYH3_k127_1389505_0 elongation factor G K02355 - - 2.817e-226 720.0
PYH3_k127_1389505_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 385.0
PYH3_k127_1389505_2 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 379.0
PYH3_k127_1389505_3 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 376.0
PYH3_k127_1389505_4 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 317.0
PYH3_k127_1389505_5 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002652 276.0
PYH3_k127_1389505_6 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000007256 72.0
PYH3_k127_139687_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 3.093e-232 750.0
PYH3_k127_139687_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K00697,K01087,K16055 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.00000000000000000000000000000000001135 148.0
PYH3_k127_139687_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000001015 78.0
PYH3_k127_1406453_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 525.0
PYH3_k127_1406453_1 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 381.0
PYH3_k127_1406453_2 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 334.0
PYH3_k127_1406453_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 319.0
PYH3_k127_1406453_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000003148 240.0
PYH3_k127_1406453_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000001439 216.0
PYH3_k127_1406453_7 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000001402 153.0
PYH3_k127_1406453_8 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000005317 99.0
PYH3_k127_1415081_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 524.0
PYH3_k127_1415081_1 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 407.0
PYH3_k127_1415081_10 Cysteine-rich CPXCG - - - 0.000000000002142 68.0
PYH3_k127_1415081_2 serine-type peptidase activity K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 310.0
PYH3_k127_1415081_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001429 280.0
PYH3_k127_1415081_4 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 271.0
PYH3_k127_1415081_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002949 241.0
PYH3_k127_1415081_6 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000001241 238.0
PYH3_k127_1415081_7 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000001519 169.0
PYH3_k127_1415081_8 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000009416 145.0
PYH3_k127_1424592_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 424.0
PYH3_k127_1424592_1 branched-chain amino acid transport system, permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 425.0
PYH3_k127_1424592_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 318.0
PYH3_k127_1424592_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 291.0
PYH3_k127_1424592_4 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001312 253.0
PYH3_k127_1424592_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000201 251.0
PYH3_k127_1424592_6 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH3_k127_1424592_7 dehydratase - - - 0.000000000000000000000000000000009467 140.0
PYH3_k127_1424592_8 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000002722 103.0
PYH3_k127_1431086_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 597.0
PYH3_k127_1431086_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
PYH3_k127_1431086_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000004836 235.0
PYH3_k127_1431086_3 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000148 183.0
PYH3_k127_1431086_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000008331 194.0
PYH3_k127_1431086_5 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000004162 141.0
PYH3_k127_1431086_6 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000558 146.0
PYH3_k127_1478046_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.694e-210 668.0
PYH3_k127_1478046_1 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
PYH3_k127_1478046_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 351.0
PYH3_k127_1478046_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 303.0
PYH3_k127_1478046_4 lactate metabolic process - - - 0.000000000000000000000000000000003705 141.0
PYH3_k127_1478046_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000009527 134.0
PYH3_k127_1478046_6 Major facilitator superfamily - - - 0.0000000000000118 81.0
PYH3_k127_1478046_7 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00003236 53.0
PYH3_k127_1492479_0 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 350.0
PYH3_k127_1492479_1 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 251.0
PYH3_k127_1492479_2 PFAM CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000256 101.0
PYH3_k127_1504132_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 477.0
PYH3_k127_1504132_1 shikimate 3-dehydrogenase (NADP+) activity K00800,K10669 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19,2.7.1.160 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 451.0
PYH3_k127_1504132_2 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 328.0
PYH3_k127_1504132_3 Oxidoreductase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0006810,GO:0008150,GO:0008152,GO:0012505,GO:0016192,GO:0016197,GO:0016482,GO:0016491,GO:0031410,GO:0031982,GO:0042147,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055114,GO:0097708 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 332.0
PYH3_k127_1504132_4 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 314.0
PYH3_k127_1504132_5 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000005254 256.0
PYH3_k127_1504132_6 - - - - 0.00000000000000000000000000000001598 137.0
PYH3_k127_1504132_7 cyclic nucleotide-binding - - - 0.0000000000000156 84.0
PYH3_k127_1525496_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.964e-228 732.0
PYH3_k127_1525496_1 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 359.0
PYH3_k127_1525496_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 320.0
PYH3_k127_1525496_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
PYH3_k127_1525496_4 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000003025 212.0
PYH3_k127_1525496_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000001824 145.0
PYH3_k127_1525496_6 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000009109 98.0
PYH3_k127_1544103_0 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 326.0
PYH3_k127_1544103_1 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000001295 183.0
PYH3_k127_1544103_2 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.000000000000000000000000000000000004339 151.0
PYH3_k127_1544103_3 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000003694 140.0
PYH3_k127_1544103_4 Amidohydrolase family - - - 0.000000002311 61.0
PYH3_k127_1589761_0 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 591.0
PYH3_k127_1589761_1 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003457 270.0
PYH3_k127_1589761_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000005414 166.0
PYH3_k127_1589761_3 PFAM Alpha beta hydrolase fold-3 domain protein - - - 0.000000000000003865 81.0
PYH3_k127_1589761_4 PIN domain - - - 0.00000000000004433 77.0
PYH3_k127_1589761_5 MlaA lipoprotein K04754 - - 0.00000000001418 70.0
PYH3_k127_1618853_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.408e-281 884.0
PYH3_k127_1618853_1 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000008688 176.0
PYH3_k127_1618853_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000003342 159.0
PYH3_k127_1618853_3 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000004621 115.0
PYH3_k127_1618853_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000004307 98.0
PYH3_k127_1618853_6 chelatase subunit ChlI K07391 - - 0.000000000000649 68.0
PYH3_k127_1659297_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 473.0
PYH3_k127_1659297_1 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
PYH3_k127_1659297_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 297.0
PYH3_k127_1659297_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002136 269.0
PYH3_k127_1659297_4 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005268 251.0
PYH3_k127_1659297_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000354 147.0
PYH3_k127_1659297_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000007982 134.0
PYH3_k127_1659297_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000003485 112.0
PYH3_k127_1659297_8 amine dehydrogenase activity - - - 0.000000000000000000000001388 107.0
PYH3_k127_1659297_9 amine dehydrogenase activity - - - 0.00000002687 58.0
PYH3_k127_173005_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 336.0
PYH3_k127_173005_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000001404 164.0
PYH3_k127_173005_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000003028 128.0
PYH3_k127_173005_3 Multicopper oxidase - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009628,GO:0009888,GO:0009987,GO:0009991,GO:0010073,GO:0012505,GO:0016020,GO:0016036,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032501,GO:0032502,GO:0033554,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048507,GO:0048856,GO:0050896,GO:0051716,GO:0052716,GO:0055114,GO:0071496,GO:0071944,GO:0080167 - 0.00000000000000004887 81.0
PYH3_k127_1735677_0 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 458.0
PYH3_k127_1735677_1 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 416.0
PYH3_k127_1735677_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 370.0
PYH3_k127_1735677_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
PYH3_k127_1735677_4 PFAM Lipase, class 3 K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
PYH3_k127_1735677_5 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000244 271.0
PYH3_k127_1735677_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
PYH3_k127_1735677_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000003817 213.0
PYH3_k127_1735677_8 atp-binding protein - - - 0.00000000000000000000000000000000000000000003279 181.0
PYH3_k127_180972_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 1.468e-283 896.0
PYH3_k127_180972_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.139e-223 708.0
PYH3_k127_180972_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 385.0
PYH3_k127_180972_11 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 369.0
PYH3_k127_180972_12 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 323.0
PYH3_k127_180972_13 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 327.0
PYH3_k127_180972_14 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004401 275.0
PYH3_k127_180972_15 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000001798 244.0
PYH3_k127_180972_16 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000001414 176.0
PYH3_k127_180972_17 Flavin reductase like domain - - - 0.00000000000000000000000000000000000001032 150.0
PYH3_k127_180972_18 methyltransferase - - - 0.000000000000000000000000000000000004587 156.0
PYH3_k127_180972_19 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000002283 147.0
PYH3_k127_180972_2 phosphate transport system permease protein K02038 - - 3.156e-207 664.0
PYH3_k127_180972_20 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000002646 147.0
PYH3_k127_180972_21 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000254 140.0
PYH3_k127_180972_22 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000003394 111.0
PYH3_k127_180972_23 EamA-like transporter family - - - 0.0000000000000000000000003597 116.0
PYH3_k127_180972_24 PFAM response regulator receiver K07657 - - 0.0000000000000000000177 96.0
PYH3_k127_180972_25 Belongs to the peptidase S1C family - - - 0.000000000000001101 87.0
PYH3_k127_180972_26 Putative zinc-finger - - - 0.0001458 53.0
PYH3_k127_180972_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.116e-199 644.0
PYH3_k127_180972_4 NAD synthase K01916 - 6.3.1.5 1.221e-195 625.0
PYH3_k127_180972_5 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 539.0
PYH3_k127_180972_6 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 497.0
PYH3_k127_180972_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 505.0
PYH3_k127_180972_8 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 414.0
PYH3_k127_180972_9 carbamoyl transferase, NodU family K00612,K16035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 413.0
PYH3_k127_1823366_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 424.0
PYH3_k127_1823366_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 423.0
PYH3_k127_1823366_2 Conserved protein of dim6 ntab family - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
PYH3_k127_1823366_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000007616 175.0
PYH3_k127_1823366_4 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000007278 136.0
PYH3_k127_1823366_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000001024 91.0
PYH3_k127_1823366_6 Thioredoxin - - - 0.000000000006971 75.0
PYH3_k127_1823366_7 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0002103 45.0
PYH3_k127_1825449_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 522.0
PYH3_k127_1825449_1 transmembrane signaling receptor activity K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 395.0
PYH3_k127_1825449_10 phosphorelay signal transduction system K02658 - - 0.0000000000000000000000000000000001062 137.0
PYH3_k127_1825449_11 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000001308 136.0
PYH3_k127_1825449_12 Conserved TM helix - - - 0.0000000000000000000000000005284 121.0
PYH3_k127_1825449_13 Two component signalling adaptor domain K02487,K06596 - - 0.00000000000000000000000478 113.0
PYH3_k127_1825449_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000003134 66.0
PYH3_k127_1825449_15 chemotaxis K02659,K03408 - - 0.00000000001457 71.0
PYH3_k127_1825449_2 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 325.0
PYH3_k127_1825449_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001733 268.0
PYH3_k127_1825449_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
PYH3_k127_1825449_5 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005137 266.0
PYH3_k127_1825449_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
PYH3_k127_1825449_7 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008223 274.0
PYH3_k127_1825449_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000001005 243.0
PYH3_k127_1825449_9 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000007327 149.0
PYH3_k127_1957851_0 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 317.0
PYH3_k127_1957851_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000339 275.0
PYH3_k127_1957851_2 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000001194 75.0
PYH3_k127_1965099_0 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 482.0
PYH3_k127_1965099_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 355.0
PYH3_k127_1965099_10 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000003395 208.0
PYH3_k127_1965099_11 Formate hydrogenlyase K12136,K15827 - - 0.0000000000000000000000000000000000000000000000000001869 189.0
PYH3_k127_1965099_12 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000008072 185.0
PYH3_k127_1965099_13 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000134 172.0
PYH3_k127_1965099_14 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000003033 142.0
PYH3_k127_1965099_15 response to copper ion K07156 - - 0.0000000000000004603 83.0
PYH3_k127_1965099_16 - - - - 0.00002835 50.0
PYH3_k127_1965099_17 - - - - 0.0003135 50.0
PYH3_k127_1965099_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 327.0
PYH3_k127_1965099_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 314.0
PYH3_k127_1965099_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 307.0
PYH3_k127_1965099_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
PYH3_k127_1965099_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002111 292.0
PYH3_k127_1965099_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
PYH3_k127_1965099_8 AsmA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008538 269.0
PYH3_k127_1965099_9 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000001624 230.0
PYH3_k127_1984192_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 510.0
PYH3_k127_1984192_1 peptidase m48, ste24p - - - 0.000000000000000000000000000000000000000000002189 181.0
PYH3_k127_1984192_2 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000002989 147.0
PYH3_k127_1984192_3 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.000000000000000000009116 96.0
PYH3_k127_1984192_4 - - - - 0.0001721 50.0
PYH3_k127_2003366_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
PYH3_k127_2003366_1 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000007928 183.0
PYH3_k127_2003366_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000003684 172.0
PYH3_k127_2003366_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000003945 137.0
PYH3_k127_2003366_4 Tetratricopeptide repeat - - - 0.000000000001371 76.0
PYH3_k127_2023692_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 2.079e-216 688.0
PYH3_k127_2023692_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 6.93e-215 689.0
PYH3_k127_2023692_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 448.0
PYH3_k127_2023692_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 398.0
PYH3_k127_2023692_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 316.0
PYH3_k127_2023692_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 304.0
PYH3_k127_2023692_6 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000002122 215.0
PYH3_k127_2023692_7 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000000003651 201.0
PYH3_k127_2027011_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 472.0
PYH3_k127_2027011_1 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 372.0
PYH3_k127_2027011_2 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000267 165.0
PYH3_k127_2027011_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000001106 66.0
PYH3_k127_2038894_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 529.0
PYH3_k127_2038894_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 443.0
PYH3_k127_2038894_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000001662 232.0
PYH3_k127_2038894_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000002703 127.0
PYH3_k127_2038894_4 integral membrane protein - - - 0.000000000000000000004512 99.0
PYH3_k127_2043771_0 - - - - 4.395e-295 917.0
PYH3_k127_2043771_1 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 568.0
PYH3_k127_2043771_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 436.0
PYH3_k127_2043771_3 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000007061 188.0
PYH3_k127_2043771_4 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000002326 180.0
PYH3_k127_2043771_5 AhpC/TSA antioxidant enzyme - - - 0.000000000000000000000000001286 116.0
PYH3_k127_2043771_6 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000001566 71.0
PYH3_k127_2043771_8 AhpC/TSA antioxidant enzyme - GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009636,GO:0009987,GO:0016209,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0005123 43.0
PYH3_k127_205501_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 321.0
PYH3_k127_205501_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000001437 166.0
PYH3_k127_205501_2 PFAM outer membrane efflux protein K15725 - - 0.00000000000009223 78.0
PYH3_k127_20742_0 3' exoribonuclease family, domain 2 K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 305.0
PYH3_k127_20742_1 N-Acetylmuramoyl-L-alanine amidase K13730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 289.0
PYH3_k127_20742_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000004696 245.0
PYH3_k127_20742_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000001823 198.0
PYH3_k127_20742_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000002823 162.0
PYH3_k127_20742_5 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000002666 141.0
PYH3_k127_20742_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000001016 95.0
PYH3_k127_20742_7 Uncharacterised nucleotidyltransferase - - - 0.000000000000002057 89.0
PYH3_k127_20742_8 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0001627 48.0
PYH3_k127_20742_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0009664 49.0
PYH3_k127_2090423_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 419.0
PYH3_k127_2090423_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000006428 68.0
PYH3_k127_2094056_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 4.487e-249 782.0
PYH3_k127_2094056_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 448.0
PYH3_k127_2094056_2 - - - - 0.00000000000000000000001062 103.0
PYH3_k127_2094056_3 Transmembrane secretion effector - - - 0.000000000000000004096 89.0
PYH3_k127_2116087_0 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 380.0
PYH3_k127_2116087_1 ATP-binding region, ATPase domain protein domain protein K00384,K01338,K11527 - 1.8.1.9,2.7.13.3,3.4.21.53 0.000000000000000000000000000000000000000000000000000000002263 225.0
PYH3_k127_2116087_2 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000000000000000000000000000000000000000000000000000004427 198.0
PYH3_k127_212099_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 509.0
PYH3_k127_212099_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000001944 199.0
PYH3_k127_212099_2 Catalyzes the NAD-dependent oxidation of glucose 6- phosphate to 6-phosphogluconolactone K19243 - 1.1.1.388 0.0000000000000000000000000000000000000000000427 174.0
PYH3_k127_212099_3 - - - - 0.0000000000000000000000000000000000002893 145.0
PYH3_k127_2123830_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 451.0
PYH3_k127_2123830_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 384.0
PYH3_k127_2123830_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000002245 127.0
PYH3_k127_2123830_3 Winged helix-turn helix - - - 0.000000000000000000000000009943 111.0
PYH3_k127_217209_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 445.0
PYH3_k127_217209_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 340.0
PYH3_k127_217209_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 289.0
PYH3_k127_2179890_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.046e-278 871.0
PYH3_k127_2179890_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 560.0
PYH3_k127_2179890_10 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000004321 199.0
PYH3_k127_2179890_11 Putative cyclase - - - 0.000000000000000000000000000000000000000000000003395 186.0
PYH3_k127_2179890_12 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000004513 166.0
PYH3_k127_2179890_13 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000004168 153.0
PYH3_k127_2179890_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 473.0
PYH3_k127_2179890_3 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 473.0
PYH3_k127_2179890_4 PFAM Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 472.0
PYH3_k127_2179890_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 446.0
PYH3_k127_2179890_6 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 422.0
PYH3_k127_2179890_7 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 381.0
PYH3_k127_2179890_8 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 372.0
PYH3_k127_2179890_9 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000002758 198.0
PYH3_k127_2196419_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 520.0
PYH3_k127_2196419_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 403.0
PYH3_k127_2196419_2 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003307 244.0
PYH3_k127_2196419_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
PYH3_k127_2196419_4 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000000000000000009183 211.0
PYH3_k127_2198183_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.5e-213 715.0
PYH3_k127_2198183_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 597.0
PYH3_k127_2198183_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000001412 201.0
PYH3_k127_2198183_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000001841 186.0
PYH3_k127_2198183_12 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000003924 181.0
PYH3_k127_2198183_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000005909 177.0
PYH3_k127_2198183_14 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000009584 129.0
PYH3_k127_2198183_15 phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000003572 119.0
PYH3_k127_2198183_16 endonuclease activity - - - 0.000000000000000000000005872 106.0
PYH3_k127_2198183_2 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 606.0
PYH3_k127_2198183_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 571.0
PYH3_k127_2198183_4 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 491.0
PYH3_k127_2198183_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 488.0
PYH3_k127_2198183_6 PFAM Na Picotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 377.0
PYH3_k127_2198183_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 329.0
PYH3_k127_2198183_8 Trypsin-like serine protease K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000838 280.0
PYH3_k127_2198183_9 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000901 190.0
PYH3_k127_2272103_0 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 316.0
PYH3_k127_2272103_1 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.00000000000000000000000000000000000000000000000000184 197.0
PYH3_k127_2272103_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000006639 161.0
PYH3_k127_2272103_3 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000004894 130.0
PYH3_k127_2291561_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 452.0
PYH3_k127_2291561_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000005992 115.0
PYH3_k127_2293052_0 COG0457 FOG TPR repeat - - - 1.438e-203 660.0
PYH3_k127_2293052_1 Carbohydrate-selective porin, OprB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 541.0
PYH3_k127_2293052_2 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 451.0
PYH3_k127_2293052_3 PFAM CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 415.0
PYH3_k127_2293052_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 297.0
PYH3_k127_2293052_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000009211 203.0
PYH3_k127_2293052_6 - - - - 0.00000000000000000000000316 108.0
PYH3_k127_2293052_7 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000001616 78.0
PYH3_k127_2336897_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.864e-245 771.0
PYH3_k127_2336897_1 histidine kinase, HAMP K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 563.0
PYH3_k127_2336897_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000002088 141.0
PYH3_k127_2336897_11 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000001007 62.0
PYH3_k127_2336897_12 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0004679 46.0
PYH3_k127_2336897_2 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 524.0
PYH3_k127_2336897_3 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 405.0
PYH3_k127_2336897_4 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007832 287.0
PYH3_k127_2336897_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000002568 258.0
PYH3_k127_2336897_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000005141 242.0
PYH3_k127_2336897_7 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
PYH3_k127_2336897_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000004301 175.0
PYH3_k127_2336897_9 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000007335 157.0
PYH3_k127_2366439_0 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1032.0
PYH3_k127_2366439_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.249e-269 854.0
PYH3_k127_2366439_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 599.0
PYH3_k127_2366439_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 319.0
PYH3_k127_2366439_4 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000004004 239.0
PYH3_k127_2366439_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000002233 190.0
PYH3_k127_2366439_6 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000000000000007845 123.0
PYH3_k127_2366439_7 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000001632 57.0
PYH3_k127_2382966_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1678.0
PYH3_k127_2382966_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 3.734e-211 660.0
PYH3_k127_2382966_2 AMP-binding enzyme C-terminal domain K04116,K12507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 501.0
PYH3_k127_2382966_3 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 353.0
PYH3_k127_2382966_4 chaperone-mediated protein complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 314.0
PYH3_k127_2382966_5 Pas domain - - - 0.0000000000000000000000000000000000000000000003961 175.0
PYH3_k127_2382966_6 Pas domain - - - 0.00000000000000000000000000000000000000000006925 168.0
PYH3_k127_2382966_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000007715 102.0
PYH3_k127_2382966_8 chaperone-mediated protein complex assembly - - - 0.00000000000000000000525 105.0
PYH3_k127_2388278_0 Nitrile hydratase K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000104 272.0
PYH3_k127_2388278_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001264 264.0
PYH3_k127_2388278_2 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000189 243.0
PYH3_k127_2388278_3 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000004332 170.0
PYH3_k127_2388278_4 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001357 119.0
PYH3_k127_2388278_5 endonuclease activity - - - 0.0000000000000000000001473 102.0
PYH3_k127_2388278_6 Nitrile hydratase beta subunit - - - 0.000000000000000000236 99.0
PYH3_k127_2400525_0 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 548.0
PYH3_k127_2400525_1 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001481 286.0
PYH3_k127_2400525_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000004095 120.0
PYH3_k127_2400525_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000003532 62.0
PYH3_k127_2401624_0 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 303.0
PYH3_k127_2401624_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 259.0
PYH3_k127_2401624_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000513 119.0
PYH3_k127_2480995_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 2.138e-262 827.0
PYH3_k127_2480995_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.142e-243 772.0
PYH3_k127_2480995_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004484 252.0
PYH3_k127_2480995_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
PYH3_k127_2480995_12 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000518 242.0
PYH3_k127_2480995_13 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000005729 246.0
PYH3_k127_2480995_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000004858 134.0
PYH3_k127_2480995_15 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000174 128.0
PYH3_k127_2480995_16 O-linked GlcNAc transferase - - - 0.0000000000000000000000000002526 126.0
PYH3_k127_2480995_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000001198 109.0
PYH3_k127_2480995_18 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000001456 96.0
PYH3_k127_2480995_19 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000003612 88.0
PYH3_k127_2480995_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.65e-217 689.0
PYH3_k127_2480995_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 1.345e-197 627.0
PYH3_k127_2480995_4 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 563.0
PYH3_k127_2480995_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 539.0
PYH3_k127_2480995_6 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 399.0
PYH3_k127_2480995_7 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 396.0
PYH3_k127_2480995_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
PYH3_k127_2480995_9 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 302.0
PYH3_k127_2490725_0 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
PYH3_k127_2490725_1 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005176 273.0
PYH3_k127_2490725_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001491 257.0
PYH3_k127_2490725_3 ABC-type Mn2 Zn2 transport K09816 - - 0.00000000000000000000000000000000000000000000000000000000002615 215.0
PYH3_k127_2490725_4 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000007547 213.0
PYH3_k127_2490725_5 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000004104 129.0
PYH3_k127_2490725_6 phosphatidate phosphatase activity - - - 0.000000000003654 74.0
PYH3_k127_2495716_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 511.0
PYH3_k127_2495716_1 PFAM Short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 374.0
PYH3_k127_2495716_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003744 281.0
PYH3_k127_2495716_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000001028 158.0
PYH3_k127_2495716_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000001309 105.0
PYH3_k127_2495716_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000001761 89.0
PYH3_k127_2532752_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 4.294e-312 974.0
PYH3_k127_2532752_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 644.0
PYH3_k127_2532752_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 329.0
PYH3_k127_2532752_11 tRNA processing K06864,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 323.0
PYH3_k127_2532752_12 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 313.0
PYH3_k127_2532752_13 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 304.0
PYH3_k127_2532752_14 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004539 278.0
PYH3_k127_2532752_15 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001693 266.0
PYH3_k127_2532752_16 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000006831 248.0
PYH3_k127_2532752_17 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 235.0
PYH3_k127_2532752_18 'Molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000000000489 226.0
PYH3_k127_2532752_19 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000001482 227.0
PYH3_k127_2532752_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 463.0
PYH3_k127_2532752_20 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000111 215.0
PYH3_k127_2532752_21 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000006129 149.0
PYH3_k127_2532752_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14751 - - 0.00000000000000000000000000000005039 133.0
PYH3_k127_2532752_23 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000002454 123.0
PYH3_k127_2532752_24 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000452 109.0
PYH3_k127_2532752_25 HNH endonuclease - - - 0.00000000000000336 77.0
PYH3_k127_2532752_26 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0001056 49.0
PYH3_k127_2532752_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 398.0
PYH3_k127_2532752_4 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 381.0
PYH3_k127_2532752_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 370.0
PYH3_k127_2532752_6 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 361.0
PYH3_k127_2532752_7 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 340.0
PYH3_k127_2532752_8 SMART Elongator protein 3 MiaB NifB K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 337.0
PYH3_k127_2532752_9 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 331.0
PYH3_k127_253940_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 567.0
PYH3_k127_253940_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000001613 204.0
PYH3_k127_253940_2 CoA-binding domain protein - - - 0.00000000000000698 75.0
PYH3_k127_2558919_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 371.0
PYH3_k127_2558919_1 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000004882 248.0
PYH3_k127_2558919_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000002438 74.0
PYH3_k127_2571086_0 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 2.464e-204 645.0
PYH3_k127_2571086_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 358.0
PYH3_k127_2571086_2 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000006896 249.0
PYH3_k127_2571086_3 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
PYH3_k127_2571086_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000002385 222.0
PYH3_k127_2571086_5 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.0000000000000000000000727 103.0
PYH3_k127_2626697_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 610.0
PYH3_k127_2626697_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000007986 198.0
PYH3_k127_2626697_2 Mandelate Racemase Muconate Lactonizing - - - 0.000000000000000003232 98.0
PYH3_k127_2626697_3 Tautomerase enzyme - - - 0.00000000003235 68.0
PYH3_k127_2626697_4 FecR protein - - - 0.0009111 53.0
PYH3_k127_2641954_0 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003166 288.0
PYH3_k127_2641954_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005679 252.0
PYH3_k127_2641954_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003684 235.0
PYH3_k127_2641954_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000001399 230.0
PYH3_k127_2641954_4 - - - - 0.000000000001958 69.0
PYH3_k127_2682701_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.346e-239 753.0
PYH3_k127_2682701_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 525.0
PYH3_k127_2682701_10 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003231 286.0
PYH3_k127_2682701_11 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000003151 248.0
PYH3_k127_2682701_12 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000006921 248.0
PYH3_k127_2682701_13 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000957 245.0
PYH3_k127_2682701_14 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000009487 244.0
PYH3_k127_2682701_15 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00003,K00058,K01752,K16843 - 1.1.1.3,1.1.1.310,1.1.1.399,1.1.1.95,4.3.1.17 0.00000000000000000000000000000000000000000000000000000000421 214.0
PYH3_k127_2682701_16 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000005809 210.0
PYH3_k127_2682701_17 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000001338 164.0
PYH3_k127_2682701_18 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002124 165.0
PYH3_k127_2682701_19 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000006649 156.0
PYH3_k127_2682701_2 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 481.0
PYH3_k127_2682701_20 Luciferase-like monooxygenase - - - 0.00000000000000000000000001103 112.0
PYH3_k127_2682701_21 Thioredoxin - - - 0.00000000000000000000000001749 124.0
PYH3_k127_2682701_22 - - - - 0.000000000000000000000007884 108.0
PYH3_k127_2682701_23 - - - - 0.0000000004549 63.0
PYH3_k127_2682701_24 - - - - 0.00000006509 60.0
PYH3_k127_2682701_3 MacB-like periplasmic core domain K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 466.0
PYH3_k127_2682701_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 467.0
PYH3_k127_2682701_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 430.0
PYH3_k127_2682701_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 390.0
PYH3_k127_2682701_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 314.0
PYH3_k127_2682701_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 319.0
PYH3_k127_2682701_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 290.0
PYH3_k127_2701091_0 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 365.0
PYH3_k127_2701091_1 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000008042 279.0
PYH3_k127_2701091_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000004882 213.0
PYH3_k127_2701091_3 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000001212 166.0
PYH3_k127_2701091_4 NIPSNAP - - - 0.00000000000000000000000000000000136 133.0
PYH3_k127_2701091_5 Carboxymuconolactone decarboxylase family - - - 0.000000000008229 68.0
PYH3_k127_2701091_6 Belongs to the GcvT family - - - 0.00000003048 66.0
PYH3_k127_2701091_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000117 50.0
PYH3_k127_2732660_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 602.0
PYH3_k127_2732660_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000001711 121.0
PYH3_k127_2732660_2 AraC-like ligand binding domain - - - 0.00000000000000000002555 95.0
PYH3_k127_2732660_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000003136 81.0
PYH3_k127_2732660_4 Tautomerase enzyme - - - 0.0000000002142 63.0
PYH3_k127_2742262_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 5.761e-230 721.0
PYH3_k127_2742262_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 561.0
PYH3_k127_2742262_10 ATP-binding region ATPase domain protein - - - 0.00000000007166 74.0
PYH3_k127_2742262_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 524.0
PYH3_k127_2742262_3 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005635 285.0
PYH3_k127_2742262_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
PYH3_k127_2742262_5 CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004452 227.0
PYH3_k127_2742262_6 Copper/zinc superoxide dismutase (SODC) - - - 0.0000000000000000000000000000000000000000001808 168.0
PYH3_k127_2742262_7 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000127 155.0
PYH3_k127_2742262_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000001903 144.0
PYH3_k127_2742262_9 Putative restriction endonuclease - - - 0.000000000000278 81.0
PYH3_k127_2742488_0 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 571.0
PYH3_k127_2742488_1 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 462.0
PYH3_k127_2742488_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 449.0
PYH3_k127_2742488_3 Peptidase, M23 - - - 0.0000000000000000000000000000000000000001101 164.0
PYH3_k127_2742488_4 PFAM conserved K07027 - - 0.00000000000000000000000000000007079 144.0
PYH3_k127_2742488_5 ECF sigma factor K03088 - - 0.0000000000000000000000000001362 125.0
PYH3_k127_2742488_6 Polymer-forming cytoskeletal - - - 0.0000000000000000000002363 101.0
PYH3_k127_2742488_7 carboxylic ester hydrolase activity - - - 0.0000008507 51.0
PYH3_k127_2773207_0 dehydrogenase - - - 3.759e-206 663.0
PYH3_k127_2773207_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 559.0
PYH3_k127_2773207_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002986 248.0
PYH3_k127_2773207_3 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000005632 231.0
PYH3_k127_2773207_4 transferase activity, transferring glycosyl groups K20444 - - 0.0000000000000000000000000000000000000000000000000000000001205 219.0
PYH3_k127_2773207_5 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.0000000000000000000000000000000000000000000000000000000001967 229.0
PYH3_k127_2773207_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000003475 186.0
PYH3_k127_2773207_7 Oxidoreductase FAD-binding domain K16246 - - 0.0000000000000000000000004997 113.0
PYH3_k127_2773207_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000006313 62.0
PYH3_k127_2773207_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0003118 51.0
PYH3_k127_2811501_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 597.0
PYH3_k127_2811501_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 537.0
PYH3_k127_2811501_10 AhpC/TSA antioxidant enzyme - - - 0.00000000000000000000000000000001123 131.0
PYH3_k127_2811501_11 GYD domain - - - 0.0000000000000000001218 92.0
PYH3_k127_2811501_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0005692 43.0
PYH3_k127_2811501_2 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 370.0
PYH3_k127_2811501_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 344.0
PYH3_k127_2811501_4 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 293.0
PYH3_k127_2811501_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005035 284.0
PYH3_k127_2811501_6 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000004983 224.0
PYH3_k127_2811501_7 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000004102 210.0
PYH3_k127_2811501_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000005919 153.0
PYH3_k127_2811501_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000003102 154.0
PYH3_k127_2843282_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K16901 - 1.14.14.8,1.14.14.9 4.649e-202 642.0
PYH3_k127_2843282_1 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 424.0
PYH3_k127_2843282_10 - - - - 0.000000000000000000000000004581 112.0
PYH3_k127_2843282_11 - - - - 0.000000002312 59.0
PYH3_k127_2843282_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 436.0
PYH3_k127_2843282_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 377.0
PYH3_k127_2843282_4 L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 362.0
PYH3_k127_2843282_5 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 366.0
PYH3_k127_2843282_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006038 291.0
PYH3_k127_2843282_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000007228 239.0
PYH3_k127_2843282_8 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000001903 206.0
PYH3_k127_2843282_9 SnoaL-like polyketide cyclase K07255 - - 0.0000000000000000000000000000000000000000000000000006287 188.0
PYH3_k127_291332_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 472.0
PYH3_k127_291332_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 372.0
PYH3_k127_291332_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001043 284.0
PYH3_k127_291332_3 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000003044 205.0
PYH3_k127_291332_4 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000002297 201.0
PYH3_k127_291332_5 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000006563 151.0
PYH3_k127_2921428_0 Sulfatase K01130 - 3.1.6.1 0.0 1185.0
PYH3_k127_2921428_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1084.0
PYH3_k127_2921428_10 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
PYH3_k127_2921428_11 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000002057 157.0
PYH3_k127_2921428_12 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000000000004194 153.0
PYH3_k127_2921428_13 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000001189 145.0
PYH3_k127_2921428_14 Alkylmercury lyase - - - 0.0000000000000000000000000000000005567 136.0
PYH3_k127_2921428_15 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000001532 119.0
PYH3_k127_2921428_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 579.0
PYH3_k127_2921428_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 522.0
PYH3_k127_2921428_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 492.0
PYH3_k127_2921428_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 439.0
PYH3_k127_2921428_6 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 377.0
PYH3_k127_2921428_7 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 332.0
PYH3_k127_2921428_8 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 314.0
PYH3_k127_2921428_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 293.0
PYH3_k127_2934221_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.371e-298 940.0
PYH3_k127_2934221_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 2.05e-205 655.0
PYH3_k127_2934221_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
PYH3_k127_2934221_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000001253 214.0
PYH3_k127_2934221_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000000000000000000000000006766 211.0
PYH3_k127_2934221_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000023 55.0
PYH3_k127_3001262_0 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 399.0
PYH3_k127_3001262_1 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 354.0
PYH3_k127_3001262_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005339 283.0
PYH3_k127_3001262_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000069 260.0
PYH3_k127_3125028_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 621.0
PYH3_k127_3125028_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009124 257.0
PYH3_k127_3125028_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000003593 239.0
PYH3_k127_3125028_3 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000000000000000000002028 240.0
PYH3_k127_3125028_4 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000124 238.0
PYH3_k127_3172984_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 324.0
PYH3_k127_3172984_1 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005513 237.0
PYH3_k127_3172984_2 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000006002 113.0
PYH3_k127_3172984_3 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000002281 93.0
PYH3_k127_317442_0 PFAM aminotransferase class-III K01845,K21585 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016740,GO:0016769,GO:0016853,GO:0016866,GO:0016869,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044464,GO:0046148,GO:0046395,GO:0046440,GO:0046483,GO:0046501,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 404.0
PYH3_k127_317442_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000001681 151.0
PYH3_k127_317442_2 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000000000001937 132.0
PYH3_k127_317442_3 ThiF family K03148,K03636,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000001386 106.0
PYH3_k127_3230850_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 428.0
PYH3_k127_3230850_1 PFAM extracellular solute-binding protein family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 374.0
PYH3_k127_3230850_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 347.0
PYH3_k127_3230850_3 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 302.0
PYH3_k127_3230850_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 287.0
PYH3_k127_3230850_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000007664 199.0
PYH3_k127_3230850_6 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.0000000000000139 81.0
PYH3_k127_3230850_7 - - - - 0.00002221 51.0
PYH3_k127_3283436_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006207 297.0
PYH3_k127_3283436_1 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00002767 51.0
PYH3_k127_3327492_0 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 428.0
PYH3_k127_3327492_1 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 398.0
PYH3_k127_3327492_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000003097 125.0
PYH3_k127_3327492_12 ABC transporter substrate binding protein K01989 - - 0.0005809 42.0
PYH3_k127_3327492_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 374.0
PYH3_k127_3327492_3 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 344.0
PYH3_k127_3327492_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008277 258.0
PYH3_k127_3327492_5 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000009601 241.0
PYH3_k127_3327492_6 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000001426 191.0
PYH3_k127_3327492_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000001948 191.0
PYH3_k127_3327492_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000003813 186.0
PYH3_k127_3327492_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000001013 165.0
PYH3_k127_3337505_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 2.477e-205 648.0
PYH3_k127_3337505_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 592.0
PYH3_k127_3337505_2 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000003958 229.0
PYH3_k127_3337505_3 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001616 197.0
PYH3_k127_3337505_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000003694 126.0
PYH3_k127_3337505_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000001635 73.0
PYH3_k127_334227_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 392.0
PYH3_k127_334227_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 319.0
PYH3_k127_334227_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001896 98.0
PYH3_k127_334227_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000006037 106.0
PYH3_k127_334227_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000003206 80.0
PYH3_k127_334227_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000006419 74.0
PYH3_k127_334227_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000001371 240.0
PYH3_k127_334227_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000115 211.0
PYH3_k127_334227_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001266 187.0
PYH3_k127_334227_5 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000005677 182.0
PYH3_k127_334227_6 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001218 165.0
PYH3_k127_334227_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000002711 134.0
PYH3_k127_334227_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004241 131.0
PYH3_k127_334227_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000437 123.0
PYH3_k127_3373217_0 PFAM FAD linked oxidase domain protein - - - 1.1e-304 964.0
PYH3_k127_3373217_1 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 1.203e-230 732.0
PYH3_k127_3373217_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000003539 82.0
PYH3_k127_3419529_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 580.0
PYH3_k127_3419529_1 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 458.0
PYH3_k127_3419529_10 FtsX-like permease family K02004 - - 0.0001147 45.0
PYH3_k127_3419529_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 456.0
PYH3_k127_3419529_3 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000001821 220.0
PYH3_k127_3419529_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000006387 214.0
PYH3_k127_3419529_5 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000003412 177.0
PYH3_k127_3419529_6 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000001687 150.0
PYH3_k127_3419529_7 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000000000000002565 143.0
PYH3_k127_3419529_8 Regulatory protein, FmdB family - - - 0.000000002028 63.0
PYH3_k127_3419529_9 PFAM NHL repeat containing protein K13735 - - 0.000004918 58.0
PYH3_k127_3496728_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 487.0
PYH3_k127_3496728_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001376 267.0
PYH3_k127_3496728_2 TPR repeat - - - 0.00000000000000000000000000000000000000000003932 172.0
PYH3_k127_3496728_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000001038 144.0
PYH3_k127_3496728_4 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.00000000000000000000000000000001125 141.0
PYH3_k127_3513811_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 601.0
PYH3_k127_3513811_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 605.0
PYH3_k127_3513811_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 295.0
PYH3_k127_3513811_3 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000435 289.0
PYH3_k127_3513811_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000007415 222.0
PYH3_k127_3513811_5 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000000000000000000001526 169.0
PYH3_k127_3585765_0 Circularly permuted ATP-grasp type 2 - - - 1.419e-214 686.0
PYH3_k127_3585765_1 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 3.197e-197 627.0
PYH3_k127_3585765_10 cellular water homeostasis K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
PYH3_k127_3585765_11 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000002201 201.0
PYH3_k127_3585765_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001394 170.0
PYH3_k127_3585765_13 - - - - 0.0000000000000192 75.0
PYH3_k127_3585765_14 - - - - 0.0000001274 62.0
PYH3_k127_3585765_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 503.0
PYH3_k127_3585765_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 449.0
PYH3_k127_3585765_4 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 445.0
PYH3_k127_3585765_5 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 392.0
PYH3_k127_3585765_6 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 340.0
PYH3_k127_3585765_7 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 290.0
PYH3_k127_3585765_8 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
PYH3_k127_3585765_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 273.0
PYH3_k127_3586742_0 Sugar (and other) transporter - - - 7.685e-216 677.0
PYH3_k127_3586742_1 Carboxyl transferase domain - - - 1.274e-209 662.0
PYH3_k127_3586742_10 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000001285 112.0
PYH3_k127_3586742_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000003997 109.0
PYH3_k127_3586742_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000001163 77.0
PYH3_k127_3586742_13 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.000000000002095 76.0
PYH3_k127_3586742_14 Tfp pilus assembly protein FimT K10926 - - 0.000001193 59.0
PYH3_k127_3586742_15 Prokaryotic N-terminal methylation motif - - - 0.0002275 51.0
PYH3_k127_3586742_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 329.0
PYH3_k127_3586742_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 295.0
PYH3_k127_3586742_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000145 278.0
PYH3_k127_3586742_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000001468 180.0
PYH3_k127_3586742_6 PFAM Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000009596 166.0
PYH3_k127_3586742_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000426 149.0
PYH3_k127_3586742_8 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000002781 136.0
PYH3_k127_3586742_9 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000002822 142.0
PYH3_k127_3607899_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 584.0
PYH3_k127_3607899_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 471.0
PYH3_k127_3607899_10 Mut7-C ubiquitin - - - 0.00000002214 60.0
PYH3_k127_3607899_11 Homeodomain-like domain - - - 0.00002399 50.0
PYH3_k127_3607899_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0001502 51.0
PYH3_k127_3607899_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 454.0
PYH3_k127_3607899_3 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007761 265.0
PYH3_k127_3607899_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000002028 224.0
PYH3_k127_3607899_5 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
PYH3_k127_3607899_6 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000003325 225.0
PYH3_k127_3607899_7 Protein of unknown function (DUF3105) - - - 0.0000000000000000000000000000000000000000001314 166.0
PYH3_k127_3607899_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000007597 67.0
PYH3_k127_3607899_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000301 69.0
PYH3_k127_3700016_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 490.0
PYH3_k127_3700016_1 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 406.0
PYH3_k127_3700016_10 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.0007961 44.0
PYH3_k127_3700016_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 388.0
PYH3_k127_3700016_3 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.000000000000000000000000000000000000000000000000000000000000000656 225.0
PYH3_k127_3700016_4 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000006558 217.0
PYH3_k127_3700016_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000003819 187.0
PYH3_k127_3700016_6 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.00000000000000000000000000000000000000000007729 163.0
PYH3_k127_3700016_7 -acetyltransferase - - - 0.00000000000000000000000001915 115.0
PYH3_k127_3706547_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 439.0
PYH3_k127_3706547_1 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 371.0
PYH3_k127_3706547_2 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000000005524 227.0
PYH3_k127_3706547_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000005496 238.0
PYH3_k127_3706547_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000008041 231.0
PYH3_k127_3706547_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000001897 139.0
PYH3_k127_3706547_6 Allophanate hydrolase subunit 1 K01941,K01965 - 6.3.4.6,6.4.1.3 0.00000000000000000005616 97.0
PYH3_k127_3738871_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 368.0
PYH3_k127_3738871_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 290.0
PYH3_k127_3738871_10 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000003954 118.0
PYH3_k127_3738871_11 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000007546 63.0
PYH3_k127_3738871_12 Redoxin - - - 0.000000983 56.0
PYH3_k127_3738871_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007485 257.0
PYH3_k127_3738871_3 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000428 256.0
PYH3_k127_3738871_4 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008157 256.0
PYH3_k127_3738871_5 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000004748 184.0
PYH3_k127_3738871_6 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000127 150.0
PYH3_k127_3738871_7 Thioredoxin - - - 0.0000000000000000000000000000000000002684 156.0
PYH3_k127_3738871_8 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000001035 135.0
PYH3_k127_3738871_9 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000000532 130.0
PYH3_k127_377945_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000001482 217.0
PYH3_k127_377945_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000002 201.0
PYH3_k127_377945_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000002119 72.0
PYH3_k127_3780208_0 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 424.0
PYH3_k127_3780208_1 Trypsin-like serine protease K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007505 278.0
PYH3_k127_3780208_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
PYH3_k127_3780208_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004401 240.0
PYH3_k127_3780208_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000006602 128.0
PYH3_k127_3780208_5 Histidine kinase K07647 - 2.7.13.3 0.0003955 50.0
PYH3_k127_3926019_0 Metallopeptidase family M24 - - - 5.119e-200 634.0
PYH3_k127_3926019_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 372.0
PYH3_k127_3926019_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 368.0
PYH3_k127_3926019_3 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002237 282.0
PYH3_k127_3926019_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000001322 203.0
PYH3_k127_3926019_5 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000002622 172.0
PYH3_k127_3926019_6 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.00000003408 57.0
PYH3_k127_3926019_7 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000007448 53.0
PYH3_k127_39289_0 Luciferase-like monooxygenase - - - 1.335e-206 648.0
PYH3_k127_39289_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 411.0
PYH3_k127_39289_2 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.0000000000002912 76.0
PYH3_k127_3936865_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.145e-219 709.0
PYH3_k127_3936865_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.745e-216 684.0
PYH3_k127_3936865_10 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000000000001701 189.0
PYH3_k127_3936865_11 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000005379 153.0
PYH3_k127_3936865_12 Ferredoxin - - - 0.000000000000000000000000000000000002155 140.0
PYH3_k127_3936865_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000005166 109.0
PYH3_k127_3936865_14 SMART Tetratricopeptide - - - 0.000000003125 65.0
PYH3_k127_3936865_15 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000229 60.0
PYH3_k127_3936865_16 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00004432 55.0
PYH3_k127_3936865_2 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 457.0
PYH3_k127_3936865_3 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 451.0
PYH3_k127_3936865_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 380.0
PYH3_k127_3936865_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 316.0
PYH3_k127_3936865_6 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 285.0
PYH3_k127_3936865_7 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000004845 271.0
PYH3_k127_3936865_8 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008844 258.0
PYH3_k127_3936865_9 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000001119 198.0
PYH3_k127_3941592_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 411.0
PYH3_k127_3941592_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000137 274.0
PYH3_k127_3941592_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005163 267.0
PYH3_k127_3941592_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000004408 230.0
PYH3_k127_3941592_4 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000004446 122.0
PYH3_k127_3950938_0 Dehydrogenase - - - 3.239e-217 701.0
PYH3_k127_3950938_1 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 606.0
PYH3_k127_3950938_2 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 499.0
PYH3_k127_3950938_3 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 472.0
PYH3_k127_3950938_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 467.0
PYH3_k127_3950938_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 350.0
PYH3_k127_3950938_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 302.0
PYH3_k127_3950938_7 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000007048 267.0
PYH3_k127_3950938_8 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000000006654 160.0
PYH3_k127_3950938_9 oxidation-reduction process - - - 0.0000000000000000000000000000000000005125 144.0
PYH3_k127_3972182_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.4e-323 1015.0
PYH3_k127_3972182_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 379.0
PYH3_k127_3972182_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 375.0
PYH3_k127_3972182_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 362.0
PYH3_k127_3972182_4 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 341.0
PYH3_k127_3972182_5 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 315.0
PYH3_k127_3972182_6 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002711 227.0
PYH3_k127_3972182_7 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000001099 149.0
PYH3_k127_3972182_8 Helix-turn-helix - - - 0.0000000000000002666 90.0
PYH3_k127_397257_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 516.0
PYH3_k127_397257_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 500.0
PYH3_k127_397257_10 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000009637 174.0
PYH3_k127_397257_11 Involved in molybdopterin and thiamine biosynthesis, family 2 K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000001788 119.0
PYH3_k127_397257_12 - - - - 0.000000000000000000000009803 109.0
PYH3_k127_397257_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000001217 91.0
PYH3_k127_397257_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 451.0
PYH3_k127_397257_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 462.0
PYH3_k127_397257_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 433.0
PYH3_k127_397257_5 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 333.0
PYH3_k127_397257_6 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 312.0
PYH3_k127_397257_7 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 314.0
PYH3_k127_397257_8 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 287.0
PYH3_k127_397257_9 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000001791 199.0
PYH3_k127_3980808_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000002473 233.0
PYH3_k127_3980808_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000969 163.0
PYH3_k127_3980808_2 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000001116 165.0
PYH3_k127_4025468_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003295 261.0
PYH3_k127_4025468_1 spermidine putrescine ABC transporter, permease K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000422 267.0
PYH3_k127_4025468_2 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000004855 100.0
PYH3_k127_4055641_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 514.0
PYH3_k127_4055641_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 465.0
PYH3_k127_4055641_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
PYH3_k127_4055641_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001934 235.0
PYH3_k127_4055641_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000000000000000000000000000000273 211.0
PYH3_k127_4055641_13 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000004924 220.0
PYH3_k127_4055641_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000002823 211.0
PYH3_k127_4055641_15 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001727 203.0
PYH3_k127_4055641_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000004186 205.0
PYH3_k127_4055641_17 Fumarylacetoacetate (FAA) hydrolase family K01617,K02554 - 4.1.1.77,4.2.1.80 0.000000000000000000000000000000000000000000000000002994 195.0
PYH3_k127_4055641_18 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000000000000003977 184.0
PYH3_k127_4055641_19 dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000003417 152.0
PYH3_k127_4055641_2 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 415.0
PYH3_k127_4055641_20 NUDIX domain - - - 0.00000000000000000000000000001042 129.0
PYH3_k127_4055641_21 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000000000000005375 107.0
PYH3_k127_4055641_22 SCP-2 sterol transfer family - - - 0.0000000000000000000004997 100.0
PYH3_k127_4055641_23 Cytochrome C' - - - 0.000000000000991 80.0
PYH3_k127_4055641_24 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.00000000002132 74.0
PYH3_k127_4055641_25 iron ion homeostasis - - - 0.00000006433 64.0
PYH3_k127_4055641_26 Zn-dependent protease, contains TPR repeats - - - 0.00002656 54.0
PYH3_k127_4055641_3 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 402.0
PYH3_k127_4055641_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 352.0
PYH3_k127_4055641_5 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 317.0
PYH3_k127_4055641_6 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 309.0
PYH3_k127_4055641_7 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001395 285.0
PYH3_k127_4055641_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 274.0
PYH3_k127_4055641_9 Belongs to the enoyl-CoA hydratase isomerase family K07546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002682 254.0
PYH3_k127_4075255_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.054e-195 619.0
PYH3_k127_4075255_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 423.0
PYH3_k127_4075255_2 domain protein - - - 0.000000000000000000000000000000000000000000000000000006528 200.0
PYH3_k127_4091476_0 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 363.0
PYH3_k127_4091476_1 hydrolase of alkaline phosphatase superfamily K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 368.0
PYH3_k127_4091476_10 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.000000000000000000000000000000000000000000000000005764 202.0
PYH3_k127_4091476_11 KR domain - - - 0.000000000000000000000000000000000000000000000008722 180.0
PYH3_k127_4091476_12 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000001306 176.0
PYH3_k127_4091476_13 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000001832 136.0
PYH3_k127_4091476_14 60Kd inner membrane protein - - - 0.000000000000000000000000000000001226 148.0
PYH3_k127_4091476_15 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000005422 132.0
PYH3_k127_4091476_16 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000002227 106.0
PYH3_k127_4091476_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 340.0
PYH3_k127_4091476_3 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
PYH3_k127_4091476_4 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003665 272.0
PYH3_k127_4091476_5 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 252.0
PYH3_k127_4091476_6 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001191 256.0
PYH3_k127_4091476_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000003433 246.0
PYH3_k127_4091476_8 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000006656 248.0
PYH3_k127_4091476_9 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005986 224.0
PYH3_k127_4140383_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.713e-221 699.0
PYH3_k127_4140383_1 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 372.0
PYH3_k127_4140383_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 359.0
PYH3_k127_4140383_3 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 327.0
PYH3_k127_4140383_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000003853 169.0
PYH3_k127_4140383_5 OstA-like protein K09774 - - 0.00000000000000001626 92.0
PYH3_k127_4140383_6 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.000001143 59.0
PYH3_k127_4140383_7 SMART CBS domain containing protein K00974 - 2.7.7.72 0.0001474 50.0
PYH3_k127_4140383_8 RNA polymerase sigma54 factor K03092 - - 0.0003638 46.0
PYH3_k127_4164843_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 2.823e-281 880.0
PYH3_k127_4164843_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 486.0
PYH3_k127_4164843_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
PYH3_k127_4164843_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 313.0
PYH3_k127_4164843_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 300.0
PYH3_k127_4164843_5 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 256.0
PYH3_k127_4164843_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000002526 179.0
PYH3_k127_4164843_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000852 169.0
PYH3_k127_4164843_8 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000001837 142.0
PYH3_k127_4178343_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 500.0
PYH3_k127_4178343_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 362.0
PYH3_k127_4178343_2 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 361.0
PYH3_k127_4178343_3 - - - - 0.000000000000000000000000000000000000000000000000000000001068 212.0
PYH3_k127_4178343_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000007599 154.0
PYH3_k127_4178343_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000002657 52.0
PYH3_k127_4202382_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
PYH3_k127_4202382_1 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 322.0
PYH3_k127_4202382_10 Rhodanese Homology Domain - - - 0.00000000000000000000000002472 113.0
PYH3_k127_4202382_11 Major facilitator superfamily K08161 - - 0.00006682 55.0
PYH3_k127_4202382_2 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 262.0
PYH3_k127_4202382_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000321 257.0
PYH3_k127_4202382_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001811 247.0
PYH3_k127_4202382_5 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000001799 205.0
PYH3_k127_4202382_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000003997 206.0
PYH3_k127_4202382_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000001004 187.0
PYH3_k127_4202382_8 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000005997 139.0
PYH3_k127_4202382_9 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000502 131.0
PYH3_k127_4211323_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 2.576e-213 689.0
PYH3_k127_4211323_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 523.0
PYH3_k127_4211323_10 - - - - 0.000000000000000000001853 98.0
PYH3_k127_4211323_11 other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000000389 89.0
PYH3_k127_4211323_2 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 370.0
PYH3_k127_4211323_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 319.0
PYH3_k127_4211323_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 291.0
PYH3_k127_4211323_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
PYH3_k127_4211323_6 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000005739 214.0
PYH3_k127_4211323_7 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000003424 212.0
PYH3_k127_4211323_8 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000005756 184.0
PYH3_k127_4211323_9 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000003418 190.0
PYH3_k127_4213014_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.706e-248 775.0
PYH3_k127_4213014_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 507.0
PYH3_k127_4213014_10 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000006246 233.0
PYH3_k127_4213014_11 COG1226 Kef-type K transport systems K08714 - - 0.000000000000000000000000000000000000000000000000000000000000007959 230.0
PYH3_k127_4213014_12 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000009706 233.0
PYH3_k127_4213014_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000446 200.0
PYH3_k127_4213014_14 - - - - 0.00000000000000004569 90.0
PYH3_k127_4213014_15 DNA-binding transcription factor activity K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000197 80.0
PYH3_k127_4213014_16 Nitrogen regulatory protein P-II - - - 0.000000000002557 74.0
PYH3_k127_4213014_17 toxin-antitoxin pair type II binding - - - 0.0003676 45.0
PYH3_k127_4213014_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 509.0
PYH3_k127_4213014_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 462.0
PYH3_k127_4213014_4 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 437.0
PYH3_k127_4213014_5 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 399.0
PYH3_k127_4213014_6 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 391.0
PYH3_k127_4213014_7 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 359.0
PYH3_k127_4213014_8 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 341.0
PYH3_k127_4213014_9 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 299.0
PYH3_k127_4305361_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 348.0
PYH3_k127_4305361_1 abc transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 287.0
PYH3_k127_4305361_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001094 284.0
PYH3_k127_4305361_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000271 98.0
PYH3_k127_4305361_4 Histidine kinase - - - 0.0000000000000000006842 92.0
PYH3_k127_4305361_5 ATP-independent chaperone mediated protein folding - - - 0.0001815 51.0
PYH3_k127_4310168_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 448.0
PYH3_k127_4310168_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000005809 210.0
PYH3_k127_4310168_2 Endoribonuclease L-PSP K09021 - - 0.00000000000000000000000000000000000006892 146.0
PYH3_k127_4310168_3 Major Facilitator Superfamily K08177 - - 0.00000000000000000004099 98.0
PYH3_k127_4310168_4 - - - - 0.000000000002345 70.0
PYH3_k127_4316423_0 Adenylate and Guanylate cyclase catalytic domain - - - 2.119e-314 995.0
PYH3_k127_4316423_1 lipopolysaccharide transport K22110 - - 3.072e-309 957.0
PYH3_k127_4316423_2 choline dehydrogenase activity - - - 4.511e-273 847.0
PYH3_k127_4316423_3 radical SAM domain protein K04034 - 1.21.98.3 1.929e-225 714.0
PYH3_k127_4316423_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 445.0
PYH3_k127_4316423_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 336.0
PYH3_k127_4316423_6 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 310.0
PYH3_k127_4316423_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002811 149.0
PYH3_k127_4316423_8 Putative zinc-finger - - - 0.00000001133 61.0
PYH3_k127_4347132_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 406.0
PYH3_k127_4347132_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002038 281.0
PYH3_k127_4347132_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000005996 205.0
PYH3_k127_4347132_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000006884 108.0
PYH3_k127_4347132_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000004702 90.0
PYH3_k127_4347132_5 dmso reductase anchor subunit K18363 - - 0.0000000688 62.0
PYH3_k127_4351594_0 benzoyl-CoA oxygenase - - - 9.056e-236 747.0
PYH3_k127_4351594_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 3.947e-223 705.0
PYH3_k127_4351594_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 385.0
PYH3_k127_4351594_3 oxidation-reduction process - - - 0.000000000000000000000000233 117.0
PYH3_k127_4351594_4 Anti-sigma-K factor rskA - - - 0.00001174 55.0
PYH3_k127_4370850_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 468.0
PYH3_k127_4370850_1 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
PYH3_k127_4370850_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 374.0
PYH3_k127_4370850_3 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 357.0
PYH3_k127_4370850_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000006662 232.0
PYH3_k127_4370850_5 Protein of unknown function (DUF2877) - - - 0.00000000000004565 78.0
PYH3_k127_4376133_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 408.0
PYH3_k127_4376133_1 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 391.0
PYH3_k127_4376133_2 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 336.0
PYH3_k127_4376133_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000004685 274.0
PYH3_k127_4376133_4 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
PYH3_k127_4376133_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000001459 211.0
PYH3_k127_4376133_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000003971 165.0
PYH3_k127_4376133_7 Phosphonate ABC transporter K02044 - - 0.000000000000000000000000000000000000000002456 169.0
PYH3_k127_4376133_8 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.00000000000000000000000000000008739 127.0
PYH3_k127_4376133_9 integral membrane protein - - - 0.000001531 56.0
PYH3_k127_4399697_0 sodium-dependent phosphate transmembrane transporter activity - - - 0.0000000000000001291 87.0
PYH3_k127_4399697_1 Major Facilitator Superfamily - - - 0.00008226 45.0
PYH3_k127_4416956_0 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
PYH3_k127_4416956_1 Radical SAM domain protein K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003449 280.0
PYH3_k127_4416956_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000004495 170.0
PYH3_k127_4416956_3 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000004783 146.0
PYH3_k127_4416956_4 - - - - 0.00000000000000000000000002963 117.0
PYH3_k127_4440951_0 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 471.0
PYH3_k127_4440951_1 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 304.0
PYH3_k127_4440951_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 258.0
PYH3_k127_4440951_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000002778 200.0
PYH3_k127_4465464_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 375.0
PYH3_k127_4465464_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 323.0
PYH3_k127_4465464_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006593 269.0
PYH3_k127_4465464_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004757 255.0
PYH3_k127_4465464_4 - - - - 0.00000000000002106 85.0
PYH3_k127_4479668_0 PFAM Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 572.0
PYH3_k127_4479668_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000685 261.0
PYH3_k127_4479668_2 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000009864 150.0
PYH3_k127_4479668_3 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000009531 142.0
PYH3_k127_4479668_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000009526 103.0
PYH3_k127_4479668_5 SMART protein phosphatase 2C domain protein - - - 0.0000000000000005987 93.0
PYH3_k127_4479668_6 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0000007907 61.0
PYH3_k127_4479668_7 SMART TRASH domain protein - - - 0.0004623 46.0
PYH3_k127_4480451_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 2.083e-200 636.0
PYH3_k127_4480451_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 554.0
PYH3_k127_4480451_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 413.0
PYH3_k127_4480451_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 320.0
PYH3_k127_4480451_4 Alpha beta hydrolase superfamily K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001784 288.0
PYH3_k127_4480451_5 DinB family - - - 0.00000000000000000000000000001156 124.0
PYH3_k127_4480451_6 chemotaxis protein K06595 GO:0003674,GO:0005488,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0020037,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0046906,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:1901363 - 0.0001122 52.0
PYH3_k127_4501271_0 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000008682 155.0
PYH3_k127_4501271_1 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000005326 149.0
PYH3_k127_4501271_2 Outer membrane lipoprotein - - - 0.0000000000000000001225 99.0
PYH3_k127_4501271_3 Putative zinc-finger - GO:0005575,GO:0016020 - 0.00001236 54.0
PYH3_k127_4510786_0 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 513.0
PYH3_k127_4510786_1 lipopolysaccharide transport K22110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 413.0
PYH3_k127_4510786_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 371.0
PYH3_k127_4510786_3 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001344 274.0
PYH3_k127_4510786_4 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000001731 111.0
PYH3_k127_4510786_5 Belongs to the UPF0276 family K09930 - - 0.0000000000000004758 79.0
PYH3_k127_4658002_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 340.0
PYH3_k127_4658002_1 symporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004271 268.0
PYH3_k127_4658002_2 MlaC protein K07323 - - 0.00000000000000000000000000000000008192 141.0
PYH3_k127_4658002_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000491 104.0
PYH3_k127_4733141_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 389.0
PYH3_k127_4733141_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 330.0
PYH3_k127_4733141_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
PYH3_k127_4733141_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000003284 118.0
PYH3_k127_4733141_4 LUD domain K00782,K18929 - - 0.00000000000000000000000004175 116.0
PYH3_k127_4733141_5 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000001448 91.0
PYH3_k127_4733141_6 haloacid dehalogenase K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000339 85.0
PYH3_k127_4777351_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 526.0
PYH3_k127_4777351_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 376.0
PYH3_k127_4777351_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 328.0
PYH3_k127_4777351_3 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 322.0
PYH3_k127_4777351_4 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000003196 129.0
PYH3_k127_4777351_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000001417 72.0
PYH3_k127_4804105_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 625.0
PYH3_k127_4804105_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001617 278.0
PYH3_k127_4804105_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08256 - 2.4.1.345,2.7.8.5 0.000000000000000000000000000000000005949 143.0
PYH3_k127_4817865_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 629.0
PYH3_k127_4817865_10 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000003228 221.0
PYH3_k127_4817865_11 Sugar (and other) transporter K08161 - - 0.00000000000000000000000000000000000000000006488 178.0
PYH3_k127_4817865_12 - - - - 0.0000000000000000000001105 99.0
PYH3_k127_4817865_13 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000001234 78.0
PYH3_k127_4817865_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 488.0
PYH3_k127_4817865_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 453.0
PYH3_k127_4817865_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 385.0
PYH3_k127_4817865_5 Serine aminopeptidase, S33 - GO:0003674,GO:0003824,GO:0004301,GO:0005488,GO:0005515,GO:0016787,GO:0016801,GO:0016803,GO:0018742,GO:0042802,GO:0042803,GO:0046983 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 387.0
PYH3_k127_4817865_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 323.0
PYH3_k127_4817865_7 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 292.0
PYH3_k127_4817865_8 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 292.0
PYH3_k127_4817865_9 Luciferase-like monooxygenase K00320,K14728 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004259 261.0
PYH3_k127_482030_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 377.0
PYH3_k127_482030_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 312.0
PYH3_k127_482030_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000193 267.0
PYH3_k127_482030_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000009161 199.0
PYH3_k127_482030_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000002644 76.0
PYH3_k127_482030_5 Carboxymuconolactone decarboxylase family - - - 0.000000001653 64.0
PYH3_k127_482536_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 6.247e-286 888.0
PYH3_k127_482536_1 Periplasmic binding protein domain K01999 - - 2.647e-195 619.0
PYH3_k127_482536_10 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000004398 153.0
PYH3_k127_482536_11 nickel cation binding K03190 - - 0.000000000000000000000000006926 121.0
PYH3_k127_482536_12 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000001077 74.0
PYH3_k127_482536_13 Protein of unknown function (DUF4089) - - - 0.00000731 51.0
PYH3_k127_482536_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 409.0
PYH3_k127_482536_3 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 375.0
PYH3_k127_482536_4 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 319.0
PYH3_k127_482536_5 TIGRFAM ABC transporter, urea, ATP-binding protein, UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 312.0
PYH3_k127_482536_6 ATPases associated with a variety of cellular activities K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
PYH3_k127_482536_7 PFAM Urease beta subunit K01429,K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000000000592 171.0
PYH3_k127_482536_8 Urease, gamma subunit - - - 0.0000000000000000000000000000000000000000000002604 168.0
PYH3_k127_482536_9 ANTAR K07183,K22010 - - 0.000000000000000000000000000000000000000001056 164.0
PYH3_k127_4877629_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 436.0
PYH3_k127_4877629_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000004246 275.0
PYH3_k127_4877629_2 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000002943 201.0
PYH3_k127_4877629_3 Conserved region in glutamate synthase - - - 0.0000000000000000004871 92.0
PYH3_k127_4877629_4 PFAM FAD binding domain K11472 - - 0.0000000008884 59.0
PYH3_k127_4879456_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 406.0
PYH3_k127_4879456_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 380.0
PYH3_k127_4879456_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 358.0
PYH3_k127_4879456_3 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000007892 241.0
PYH3_k127_4879456_4 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000003964 153.0
PYH3_k127_4879456_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000003129 97.0
PYH3_k127_4879456_6 - - - - 0.0003345 45.0
PYH3_k127_4914596_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 3.319e-217 694.0
PYH3_k127_4914596_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 503.0
PYH3_k127_4914596_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 378.0
PYH3_k127_4914596_3 Gaf domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 368.0
PYH3_k127_4914596_4 PFAM aminotransferase class V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000007198 88.0
PYH3_k127_4934170_0 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 604.0
PYH3_k127_4934170_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 437.0
PYH3_k127_4934170_2 - - - - 0.000000000000001629 81.0
PYH3_k127_4955340_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 443.0
PYH3_k127_4955340_1 argininosuccinate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 369.0
PYH3_k127_4955340_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
PYH3_k127_4955340_3 Sterol carrier protein - - - 0.00000000000000000000000000000000000001347 149.0
PYH3_k127_4955340_4 - - - - 0.000000000000000000000000427 113.0
PYH3_k127_4955340_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000004693 107.0
PYH3_k127_4969059_0 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 488.0
PYH3_k127_4969059_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 481.0
PYH3_k127_4969059_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 359.0
PYH3_k127_4969059_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 333.0
PYH3_k127_4969059_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004611 290.0
PYH3_k127_4969059_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001303 270.0
PYH3_k127_4969059_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 257.0
PYH3_k127_4969059_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000001771 214.0
PYH3_k127_4995640_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 499.0
PYH3_k127_4995640_1 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 421.0
PYH3_k127_4995640_2 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 349.0
PYH3_k127_4995640_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 275.0
PYH3_k127_4995640_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000001077 155.0
PYH3_k127_4995640_5 Putative zinc-finger - - - 0.000000001502 71.0
PYH3_k127_4995640_6 ABC transporter substrate binding protein K01989 - - 0.0000005113 51.0
PYH3_k127_5037406_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1653.0
PYH3_k127_5037406_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003674 254.0
PYH3_k127_5037406_2 Lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000001421 207.0
PYH3_k127_5037406_3 YacP-like NYN domain K06962 - - 0.00000000000000005296 87.0
PYH3_k127_5103756_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1475.0
PYH3_k127_5103756_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 514.0
PYH3_k127_5103756_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000002156 126.0
PYH3_k127_5103756_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000003413 61.0
PYH3_k127_5117018_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 2.968e-252 794.0
PYH3_k127_5117018_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 408.0
PYH3_k127_5117018_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001098 82.0
PYH3_k127_5117018_11 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000001641 62.0
PYH3_k127_5117018_12 Protein of unknown function (DUF721) - - - 0.0000001527 60.0
PYH3_k127_5117018_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0001232 53.0
PYH3_k127_5117018_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 383.0
PYH3_k127_5117018_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 369.0
PYH3_k127_5117018_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 325.0
PYH3_k127_5117018_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 311.0
PYH3_k127_5117018_6 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002372 288.0
PYH3_k127_5117018_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000007991 221.0
PYH3_k127_5117018_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000004625 172.0
PYH3_k127_5117018_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000006281 142.0
PYH3_k127_5122068_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 5.05e-269 851.0
PYH3_k127_5122068_1 Protein export membrane protein K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 497.0
PYH3_k127_5122068_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 487.0
PYH3_k127_5122068_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 428.0
PYH3_k127_5122068_4 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001558 269.0
PYH3_k127_5122068_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005611 253.0
PYH3_k127_5122068_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000002482 193.0
PYH3_k127_5122068_7 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000005336 109.0
PYH3_k127_5122068_8 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000002201 103.0
PYH3_k127_5122068_9 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000002278 92.0
PYH3_k127_5147139_0 Domain of unknown function (DUF1998) K06877 - - 1.288e-242 772.0
PYH3_k127_5147139_1 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 374.0
PYH3_k127_5147139_2 VanZ like family - - - 0.00000000001233 70.0
PYH3_k127_5180486_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 1.824e-206 655.0
PYH3_k127_5180486_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 603.0
PYH3_k127_5180486_10 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000003136 224.0
PYH3_k127_5180486_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000168 129.0
PYH3_k127_5180486_12 DinB family - - - 0.000000000000000001775 93.0
PYH3_k127_5180486_13 Serine aminopeptidase, S33 - - - 0.00001003 54.0
PYH3_k127_5180486_14 SnoaL-like domain - - - 0.0009687 42.0
PYH3_k127_5180486_2 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 473.0
PYH3_k127_5180486_3 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 480.0
PYH3_k127_5180486_4 transporter, DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 453.0
PYH3_k127_5180486_5 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 417.0
PYH3_k127_5180486_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 383.0
PYH3_k127_5180486_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 348.0
PYH3_k127_5180486_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
PYH3_k127_5180486_9 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002616 279.0
PYH3_k127_519141_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 501.0
PYH3_k127_519141_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 486.0
PYH3_k127_519141_10 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000004973 93.0
PYH3_k127_519141_2 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 478.0
PYH3_k127_519141_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 379.0
PYH3_k127_519141_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 349.0
PYH3_k127_519141_5 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000312 298.0
PYH3_k127_519141_6 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000005428 237.0
PYH3_k127_519141_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000007469 196.0
PYH3_k127_519141_8 Belongs to the bacterial solute-binding protein 9 family K02077,K09815 - - 0.000000000000000000000000000000000000000000000000003729 188.0
PYH3_k127_519141_9 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000001336 191.0
PYH3_k127_5212888_0 ABC transporter - - - 3.231e-268 835.0
PYH3_k127_5212888_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 422.0
PYH3_k127_5212888_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 385.0
PYH3_k127_5212888_3 amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 366.0
PYH3_k127_5212888_4 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 347.0
PYH3_k127_5212888_5 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 230.0
PYH3_k127_5215680_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 2.315e-194 616.0
PYH3_k127_5215680_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 598.0
PYH3_k127_5215680_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 459.0
PYH3_k127_5215680_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 354.0
PYH3_k127_5215680_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 349.0
PYH3_k127_5215680_5 2-phosphosulpholactate phosphatase - - - 0.00000000000000000002323 97.0
PYH3_k127_5215740_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 2.886e-210 664.0
PYH3_k127_5215740_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 517.0
PYH3_k127_5215740_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 283.0
PYH3_k127_5215740_3 domain protein K01992,K06994 - - 0.00000000000000000000000000000000000000000000000000000000000002608 228.0
PYH3_k127_5215740_4 PFAM Dimethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001332 201.0
PYH3_k127_5215740_5 - - - - 0.0000000000000000000000000001285 121.0
PYH3_k127_5215740_6 Rieske [2Fe-2S] domain - - - 0.00000000000000000000009514 101.0
PYH3_k127_5228457_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 473.0
PYH3_k127_5228457_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 450.0
PYH3_k127_5228457_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000001314 144.0
PYH3_k127_5239651_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000001693 165.0
PYH3_k127_5239651_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000004028 165.0
PYH3_k127_5245695_0 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 359.0
PYH3_k127_5245695_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 344.0
PYH3_k127_5245695_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20454 - 4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 344.0
PYH3_k127_5245695_3 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000002748 191.0
PYH3_k127_5263489_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 432.0
PYH3_k127_5263489_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000008382 216.0
PYH3_k127_5263489_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000006315 94.0
PYH3_k127_5263489_3 - - - - 0.0000002003 59.0
PYH3_k127_5278200_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 554.0
PYH3_k127_5278200_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 488.0
PYH3_k127_537493_0 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 451.0
PYH3_k127_537493_1 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000334 221.0
PYH3_k127_537493_2 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000005617 183.0
PYH3_k127_537493_3 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000006378 172.0
PYH3_k127_5406087_0 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 479.0
PYH3_k127_5406087_1 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 430.0
PYH3_k127_5406087_2 Cysteine-rich domain protein K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000513 267.0
PYH3_k127_5406087_3 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000711 162.0
PYH3_k127_5406087_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000005918 107.0
PYH3_k127_5411898_0 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 572.0
PYH3_k127_5411898_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 460.0
PYH3_k127_5411898_2 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000001066 260.0
PYH3_k127_5411898_3 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000001152 196.0
PYH3_k127_5411898_4 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000003796 123.0
PYH3_k127_5411898_5 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000001987 77.0
PYH3_k127_5411898_6 PFAM transport-associated K04065 - - 0.000000006079 64.0
PYH3_k127_5421481_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.784e-200 634.0
PYH3_k127_5421481_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 323.0
PYH3_k127_5421481_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000005101 145.0
PYH3_k127_5421481_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000614 139.0
PYH3_k127_5421481_12 Ribosomal protein L30 K02907 - - 0.0000000000001 74.0
PYH3_k127_5421481_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000004386 66.0
PYH3_k127_5421481_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 268.0
PYH3_k127_5421481_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000008293 249.0
PYH3_k127_5421481_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000009254 211.0
PYH3_k127_5421481_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000002099 210.0
PYH3_k127_5421481_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000008721 195.0
PYH3_k127_5421481_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001244 191.0
PYH3_k127_5421481_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000002097 168.0
PYH3_k127_5421481_9 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001884 166.0
PYH3_k127_5450814_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.026e-219 690.0
PYH3_k127_5450814_1 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 612.0
PYH3_k127_5450814_10 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000001633 175.0
PYH3_k127_5450814_11 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000009932 178.0
PYH3_k127_5450814_12 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000004438 160.0
PYH3_k127_5450814_13 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.000000000000000000000000000000000000003501 165.0
PYH3_k127_5450814_14 regulation of translation K03530 - - 0.0000000000000000000000000000001646 126.0
PYH3_k127_5450814_15 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000002089 119.0
PYH3_k127_5450814_16 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000722 106.0
PYH3_k127_5450814_17 response regulator, receiver - - - 0.00000000000166 74.0
PYH3_k127_5450814_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 542.0
PYH3_k127_5450814_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 437.0
PYH3_k127_5450814_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 395.0
PYH3_k127_5450814_5 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 310.0
PYH3_k127_5450814_6 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000623 279.0
PYH3_k127_5450814_7 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 262.0
PYH3_k127_5450814_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000003195 230.0
PYH3_k127_5450814_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001872 203.0
PYH3_k127_5455449_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 368.0
PYH3_k127_5455449_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000001857 190.0
PYH3_k127_5455449_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000002557 82.0
PYH3_k127_5455449_3 acetyltransferase - - - 0.000000007847 58.0
PYH3_k127_5455449_4 Binding-protein-dependent transport system inner membrane component K02026,K05815 - - 0.0000002247 53.0
PYH3_k127_5464334_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
PYH3_k127_5464334_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000001247 235.0
PYH3_k127_5464334_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000004649 151.0
PYH3_k127_5464334_3 Protein conserved in bacteria K06320 - - 0.0000000000000000000000000000000001691 145.0
PYH3_k127_5464334_4 Cytochrome c K08738 - - 0.00000000000000000000000000000006044 130.0
PYH3_k127_5472231_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1088.0
PYH3_k127_5472231_1 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 554.0
PYH3_k127_5472231_10 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000007687 207.0
PYH3_k127_5472231_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000007987 207.0
PYH3_k127_5472231_12 Histidine kinase K02482,K03557 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000002172 207.0
PYH3_k127_5472231_13 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000001453 194.0
PYH3_k127_5472231_14 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000716 157.0
PYH3_k127_5472231_15 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000006511 128.0
PYH3_k127_5472231_16 Flavin-nucleotide-binding protein K07005 - - 0.00000000000000000004039 98.0
PYH3_k127_5472231_17 - - - - 0.000000000000000001281 87.0
PYH3_k127_5472231_18 - - - - 0.00000000000004092 82.0
PYH3_k127_5472231_2 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 377.0
PYH3_k127_5472231_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 321.0
PYH3_k127_5472231_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 322.0
PYH3_k127_5472231_5 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 313.0
PYH3_k127_5472231_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 293.0
PYH3_k127_5472231_7 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007715 254.0
PYH3_k127_5472231_8 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000001079 248.0
PYH3_k127_5472231_9 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
PYH3_k127_5527545_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 355.0
PYH3_k127_5527545_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 338.0
PYH3_k127_5527545_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000009993 198.0
PYH3_k127_5527545_3 Thioesterase-like superfamily - - - 0.0000000000000000000000000000003372 128.0
PYH3_k127_5527545_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000001627 124.0
PYH3_k127_5527545_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000001938 68.0
PYH3_k127_5534735_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000004987 117.0
PYH3_k127_5534735_2 Helix-hairpin-helix motif - - - 0.0000000000000000000003241 101.0
PYH3_k127_5575740_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1328.0
PYH3_k127_5575740_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1111.0
PYH3_k127_5575740_11 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.0000005226 60.0
PYH3_k127_5575740_2 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 616.0
PYH3_k127_5575740_3 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 598.0
PYH3_k127_5575740_4 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 517.0
PYH3_k127_5575740_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 430.0
PYH3_k127_5575740_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 307.0
PYH3_k127_5575740_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000004465 211.0
PYH3_k127_5575740_8 sulfur oxidation protein soxY K17226 - - 0.0000000000000000004936 93.0
PYH3_k127_5575740_9 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000002085 61.0
PYH3_k127_562177_0 Thiamine pyrophosphate enzyme, central domain - - - 9.454e-248 808.0
PYH3_k127_562177_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.456e-245 801.0
PYH3_k127_562177_2 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 495.0
PYH3_k127_562177_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
PYH3_k127_562177_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 347.0
PYH3_k127_562177_5 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 289.0
PYH3_k127_562177_6 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004331 290.0
PYH3_k127_562177_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000003392 94.0
PYH3_k127_562177_8 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000004158 74.0
PYH3_k127_562177_9 DinB superfamily - - - 0.00000000000005291 84.0
PYH3_k127_5628836_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.23e-248 779.0
PYH3_k127_5628836_1 SNF2 family N-terminal domain - - - 4.624e-233 733.0
PYH3_k127_5628836_10 PFAM SWIM zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
PYH3_k127_5628836_11 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000001067 238.0
PYH3_k127_5628836_12 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001716 245.0
PYH3_k127_5628836_13 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000788 234.0
PYH3_k127_5628836_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000006507 172.0
PYH3_k127_5628836_15 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000002005 129.0
PYH3_k127_5628836_16 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.000000000000000000000000001135 124.0
PYH3_k127_5628836_17 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000003678 80.0
PYH3_k127_5628836_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 573.0
PYH3_k127_5628836_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 481.0
PYH3_k127_5628836_4 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 453.0
PYH3_k127_5628836_5 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
PYH3_k127_5628836_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 364.0
PYH3_k127_5628836_7 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 318.0
PYH3_k127_5628836_8 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 300.0
PYH3_k127_5628836_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000933 287.0
PYH3_k127_5630731_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 604.0
PYH3_k127_5630731_1 penicillin-binding protein K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 469.0
PYH3_k127_5630731_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 404.0
PYH3_k127_5630731_3 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 290.0
PYH3_k127_5630731_4 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000008067 226.0
PYH3_k127_5630731_5 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000003697 183.0
PYH3_k127_5631888_0 DNA polymerase type-B family K02336 - 2.7.7.7 2.614e-223 716.0
PYH3_k127_5631888_1 Putative modulator of DNA gyrase K03568 - - 2.846e-208 662.0
PYH3_k127_5631888_10 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000024 190.0
PYH3_k127_5631888_11 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000406 189.0
PYH3_k127_5631888_12 dienelactone hydrolase - - - 0.000000000000000000000000000000003228 146.0
PYH3_k127_5631888_13 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000867 113.0
PYH3_k127_5631888_14 lipopolysaccharide transmembrane transporter activity K07058 - - 0.000000000000000000222 102.0
PYH3_k127_5631888_15 DSBA-like thioredoxin domain - - - 0.000000000000000001585 92.0
PYH3_k127_5631888_16 RDD family - - - 0.000000000000000003585 91.0
PYH3_k127_5631888_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000001291 61.0
PYH3_k127_5631888_18 Domain of unknown function (DUF309) K09763 - - 0.00000001296 66.0
PYH3_k127_5631888_2 metallopeptidase activity K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 452.0
PYH3_k127_5631888_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 382.0
PYH3_k127_5631888_4 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 362.0
PYH3_k127_5631888_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 340.0
PYH3_k127_5631888_6 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000002009 269.0
PYH3_k127_5631888_7 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000243 250.0
PYH3_k127_5631888_8 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000004844 243.0
PYH3_k127_5631888_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000009742 230.0
PYH3_k127_5645613_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 602.0
PYH3_k127_5645613_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 462.0
PYH3_k127_5645613_2 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 364.0
PYH3_k127_5645613_3 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000003975 135.0
PYH3_k127_5648698_0 amino acid - - - 2.391e-211 674.0
PYH3_k127_5648698_1 Amino acid permease - - - 1.103e-206 659.0
PYH3_k127_5648698_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000001102 96.0
PYH3_k127_5648698_11 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000001485 86.0
PYH3_k127_5648698_12 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000007588 51.0
PYH3_k127_5648698_13 Protein of unknown function (DUF971) - - - 0.00004266 50.0
PYH3_k127_5648698_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 494.0
PYH3_k127_5648698_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 379.0
PYH3_k127_5648698_4 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000003297 195.0
PYH3_k127_5648698_5 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000704 160.0
PYH3_k127_5648698_6 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000002782 152.0
PYH3_k127_5648698_7 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000002604 139.0
PYH3_k127_5648698_8 8-oxoguanine DNA glycosylase K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.0000000000000000000000000000000001017 144.0
PYH3_k127_5648698_9 PFAM SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.00000000000000000000000001362 123.0
PYH3_k127_567851_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 7.7e-213 674.0
PYH3_k127_567851_1 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 366.0
PYH3_k127_567851_10 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000001119 133.0
PYH3_k127_567851_11 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000001709 113.0
PYH3_k127_567851_12 Bifunctional nuclease K08999 - - 0.0000000000000000000000005081 115.0
PYH3_k127_567851_13 Thioesterase superfamily - - - 0.00004685 54.0
PYH3_k127_567851_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 348.0
PYH3_k127_567851_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
PYH3_k127_567851_4 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 262.0
PYH3_k127_567851_5 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000002706 258.0
PYH3_k127_567851_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006606 256.0
PYH3_k127_567851_7 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000008043 187.0
PYH3_k127_567851_8 major facilitator superfamily - - - 0.000000000000000000000000000000000000001022 164.0
PYH3_k127_567851_9 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.00000000000000000000000000000000000001802 156.0
PYH3_k127_5683086_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 561.0
PYH3_k127_5683086_1 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 379.0
PYH3_k127_5683086_10 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000003973 78.0
PYH3_k127_5683086_2 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 375.0
PYH3_k127_5683086_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 345.0
PYH3_k127_5683086_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 346.0
PYH3_k127_5683086_5 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
PYH3_k127_5683086_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000905 237.0
PYH3_k127_5683086_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000003429 165.0
PYH3_k127_5683086_8 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000003586 145.0
PYH3_k127_5683086_9 Histidine kinase - - - 0.0000000000000000000001255 103.0
PYH3_k127_5707183_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1149.0
PYH3_k127_5707183_1 Belongs to the ClpA ClpB family K03696 - - 5e-324 1009.0
PYH3_k127_5707183_10 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 347.0
PYH3_k127_5707183_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 344.0
PYH3_k127_5707183_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 325.0
PYH3_k127_5707183_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 321.0
PYH3_k127_5707183_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 307.0
PYH3_k127_5707183_15 inositol 2-dehydrogenase activity K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 299.0
PYH3_k127_5707183_16 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 300.0
PYH3_k127_5707183_17 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000001775 266.0
PYH3_k127_5707183_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000002298 247.0
PYH3_k127_5707183_19 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000003453 236.0
PYH3_k127_5707183_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 6.419e-298 939.0
PYH3_k127_5707183_20 (Rhomboid) family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000001751 228.0
PYH3_k127_5707183_21 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000001626 182.0
PYH3_k127_5707183_22 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000599 180.0
PYH3_k127_5707183_23 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000000004315 171.0
PYH3_k127_5707183_24 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000007635 139.0
PYH3_k127_5707183_25 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001326 137.0
PYH3_k127_5707183_26 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000001871 106.0
PYH3_k127_5707183_27 SMART helix-turn-helix domain protein K15539 - - 0.00000000000000000000026 108.0
PYH3_k127_5707183_28 Collagen alpha-1(III) K19719,K19720 GO:0001101,GO:0001501,GO:0001568,GO:0001775,GO:0001944,GO:0002020,GO:0002682,GO:0002683,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005581,GO:0005583,GO:0005586,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006464,GO:0006807,GO:0006950,GO:0007154,GO:0007155,GO:0007160,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007229,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007517,GO:0007596,GO:0007599,GO:0008150,GO:0008152,GO:0009314,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009887,GO:0009888,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010721,GO:0012505,GO:0016043,GO:0018149,GO:0019538,GO:0019838,GO:0019899,GO:0021537,GO:0021543,GO:0021987,GO:0022008,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030168,GO:0030198,GO:0030199,GO:0030334,GO:0030336,GO:0030900,GO:0031012,GO:0031589,GO:0031974,GO:0032501,GO:0032502,GO:0032879,GO:0032991,GO:0034097,GO:0035023,GO:0035025,GO:0035239,GO:0035295,GO:0035904,GO:0035909,GO:0036211,GO:0040012,GO:0040013,GO:0042060,GO:0042221,GO:0043062,GO:0043170,GO:0043200,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043588,GO:0043933,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045595,GO:0045596,GO:0046332,GO:0046578,GO:0046579,GO:0048407,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048565,GO:0048583,GO:0048584,GO:0048585,GO:0048644,GO:0048699,GO:0048729,GO:0048731,GO:0048745,GO:0048844,GO:0048856,GO:0048869,GO:0050767,GO:0050768,GO:0050776,GO:0050777,GO:0050789,GO:0050793,GO:0050794,GO:0050817,GO:0050839,GO:0050878,GO:0050896,GO:0051056,GO:0051057,GO:0051093,GO:0051239,GO:0051241,GO:0051270,GO:0051271,GO:0051716,GO:0051960,GO:0051961,GO:0055123,GO:0060284,GO:0060322,GO:0060414,GO:0060415,GO:0060537,GO:0060840,GO:0061061,GO:0062023,GO:0065007,GO:0065008,GO:0070013,GO:0070848,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071363,GO:0071417,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0097435,GO:0098643,GO:0098644,GO:0099080,GO:0099081,GO:0099512,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533,GO:2000026,GO:2000145,GO:2000146,GO:2001222,GO:2001223 - 0.000002366 57.0
PYH3_k127_5707183_29 Belongs to the peptidase M16 family K07263 - - 0.0005076 46.0
PYH3_k127_5707183_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 573.0
PYH3_k127_5707183_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007823 564.0
PYH3_k127_5707183_5 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 533.0
PYH3_k127_5707183_6 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 486.0
PYH3_k127_5707183_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 411.0
PYH3_k127_5707183_8 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 411.0
PYH3_k127_5707183_9 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 351.0
PYH3_k127_5715259_0 Polysaccharide deacetylase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 295.0
PYH3_k127_5715259_1 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000002062 162.0
PYH3_k127_5715259_2 - - - - 0.00000000000000000000000000000000000004177 159.0
PYH3_k127_5764892_0 Peptidase dimerisation domain K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 402.0
PYH3_k127_5764892_1 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 293.0
PYH3_k127_5764892_10 Thioesterase family - - - 0.00000000000000000000000000000004195 129.0
PYH3_k127_5764892_11 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000267 125.0
PYH3_k127_5764892_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001622 289.0
PYH3_k127_5764892_3 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000154 267.0
PYH3_k127_5764892_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 269.0
PYH3_k127_5764892_5 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003626 251.0
PYH3_k127_5764892_6 Receptor family ligand binding region family protein 22 K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004655 269.0
PYH3_k127_5764892_7 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000001579 202.0
PYH3_k127_5764892_8 PFAM NUDIX domain - - - 0.00000000000000000000000000000000000000000000003797 175.0
PYH3_k127_5764892_9 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000002567 143.0
PYH3_k127_5782945_0 Belongs to the CinA family - - - 1.262e-202 639.0
PYH3_k127_5782945_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000186 226.0
PYH3_k127_5782945_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000004838 222.0
PYH3_k127_5782945_3 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000006459 198.0
PYH3_k127_5782945_4 extracellular solute-binding protein, family 5 - - - 0.0000000000000000000000000000000000000000000000000008785 205.0
PYH3_k127_5782945_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000008447 174.0
PYH3_k127_5782945_6 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.000000000000000000000000000000000000002371 156.0
PYH3_k127_5782945_7 methyltransferase - - - 0.00007066 46.0
PYH3_k127_5807389_0 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 554.0
PYH3_k127_5807389_1 Protein of unknown function K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 416.0
PYH3_k127_5807389_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000001872 93.0
PYH3_k127_5807389_11 - - - - 0.0000006526 57.0
PYH3_k127_5807389_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 316.0
PYH3_k127_5807389_3 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000000000000000000001649 229.0
PYH3_k127_5807389_4 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000000000000000000177 206.0
PYH3_k127_5807389_5 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000003347 208.0
PYH3_k127_5807389_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000002088 183.0
PYH3_k127_5807389_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000006712 177.0
PYH3_k127_5807389_8 Protein of unknown function - - - 0.000000000000000000000000000000000000001247 171.0
PYH3_k127_5807389_9 - - - - 0.000000000000000000000000000000004478 137.0
PYH3_k127_5864740_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 2.635e-235 761.0
PYH3_k127_5864740_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 568.0
PYH3_k127_5864740_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 483.0
PYH3_k127_5864740_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 419.0
PYH3_k127_5864740_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 362.0
PYH3_k127_5864740_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 357.0
PYH3_k127_5864740_6 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
PYH3_k127_5864740_7 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005121 265.0
PYH3_k127_5864740_8 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000005093 179.0
PYH3_k127_5878878_0 Bacterial sugar transferase K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 501.0
PYH3_k127_5878878_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000009836 190.0
PYH3_k127_5901886_0 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 595.0
PYH3_k127_5901886_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 554.0
PYH3_k127_5901886_2 L-carnitine dehydratase bile acid-inducible protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 545.0
PYH3_k127_5901886_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 385.0
PYH3_k127_5901886_4 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
PYH3_k127_5901886_5 PFAM MaoC like domain - - - 0.000000000000000000002475 109.0
PYH3_k127_5912584_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 537.0
PYH3_k127_5912584_1 ABC transporter K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 307.0
PYH3_k127_5912584_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000004604 259.0
PYH3_k127_5912584_3 Belongs to the CinA family - - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
PYH3_k127_5912584_4 - - - - 0.000000000000000000000000000004305 138.0
PYH3_k127_5912584_5 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000006607 117.0
PYH3_k127_5912584_6 Major Facilitator Superfamily - - - 0.000000000000000001344 89.0
PYH3_k127_5924617_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 443.0
PYH3_k127_5924617_1 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 417.0
PYH3_k127_5924617_10 MaoC like domain - - - 0.0000000000000000000000000000000000000001178 156.0
PYH3_k127_5924617_11 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000008518 132.0
PYH3_k127_5924617_12 dehydratase - - - 0.000000000005501 77.0
PYH3_k127_5924617_13 N-terminal half of MaoC dehydratase - - - 0.00000001294 60.0
PYH3_k127_5924617_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 366.0
PYH3_k127_5924617_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
PYH3_k127_5924617_4 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 377.0
PYH3_k127_5924617_5 ABC-type sugar K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 329.0
PYH3_k127_5924617_6 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 322.0
PYH3_k127_5924617_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
PYH3_k127_5924617_8 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000108 228.0
PYH3_k127_5924617_9 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000003076 181.0
PYH3_k127_5944103_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 550.0
PYH3_k127_5944103_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 559.0
PYH3_k127_5944103_10 Tripartite tricarboxylate transporter TctB family - - - 0.00000001204 63.0
PYH3_k127_5944103_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 385.0
PYH3_k127_5944103_3 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 342.0
PYH3_k127_5944103_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 333.0
PYH3_k127_5944103_5 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 315.0
PYH3_k127_5944103_6 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006497 246.0
PYH3_k127_5944103_7 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000002216 126.0
PYH3_k127_5944103_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000003442 98.0
PYH3_k127_5944103_9 Alcohol dehydrogenase GroES-like domain K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000001937 69.0
PYH3_k127_5990907_0 4Fe-4S dicluster domain K00184 - - 3.305e-211 692.0
PYH3_k127_5990907_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 549.0
PYH3_k127_5990907_10 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000002113 128.0
PYH3_k127_5990907_11 Transcriptional regulator - - - 0.000000000000000000000002026 109.0
PYH3_k127_5990907_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000003129 111.0
PYH3_k127_5990907_13 ThiF family K03148,K03636,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000001851 99.0
PYH3_k127_5990907_14 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000007364 80.0
PYH3_k127_5990907_2 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
PYH3_k127_5990907_3 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 509.0
PYH3_k127_5990907_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 438.0
PYH3_k127_5990907_5 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 337.0
PYH3_k127_5990907_6 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000319 230.0
PYH3_k127_5990907_7 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000001327 207.0
PYH3_k127_5990907_8 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000001391 194.0
PYH3_k127_5990907_9 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000002475 138.0
PYH3_k127_5998578_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 1.686e-199 629.0
PYH3_k127_5998578_1 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 567.0
PYH3_k127_5998578_10 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000008857 217.0
PYH3_k127_5998578_11 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000001133 159.0
PYH3_k127_5998578_12 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000002522 164.0
PYH3_k127_5998578_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000004469 118.0
PYH3_k127_5998578_14 - - - - 0.00000000000000000000003835 107.0
PYH3_k127_5998578_15 InterPro IPR007367 - - - 0.000000000000000000005792 102.0
PYH3_k127_5998578_16 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000001092 104.0
PYH3_k127_5998578_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000004738 91.0
PYH3_k127_5998578_18 Redoxin K03564 - 1.11.1.15 0.00000000001071 69.0
PYH3_k127_5998578_19 - - - - 0.000000008418 64.0
PYH3_k127_5998578_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 499.0
PYH3_k127_5998578_20 Redoxin K03386 - 1.11.1.15 0.000001171 51.0
PYH3_k127_5998578_21 - - - - 0.0001718 51.0
PYH3_k127_5998578_22 Transposase - - - 0.0007587 49.0
PYH3_k127_5998578_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 363.0
PYH3_k127_5998578_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 356.0
PYH3_k127_5998578_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 346.0
PYH3_k127_5998578_6 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 327.0
PYH3_k127_5998578_7 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005923 284.0
PYH3_k127_5998578_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000021 270.0
PYH3_k127_6033405_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1093.0
PYH3_k127_6033405_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 508.0
PYH3_k127_6033405_2 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000009225 183.0
PYH3_k127_6033405_3 FixH - - - 0.00000000000000000000002977 107.0
PYH3_k127_6033405_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000001167 90.0
PYH3_k127_6033405_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000001254 68.0
PYH3_k127_6033405_6 Sulphur transport K07112 - - 0.000003537 50.0
PYH3_k127_6033405_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000006353 50.0
PYH3_k127_6085218_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 502.0
PYH3_k127_6085218_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 383.0
PYH3_k127_6085218_10 Nitronate monooxygenase K00459 - 1.13.12.16 0.00004089 48.0
PYH3_k127_6085218_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 349.0
PYH3_k127_6085218_3 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 335.0
PYH3_k127_6085218_4 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000001578 227.0
PYH3_k127_6085218_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000001563 192.0
PYH3_k127_6085218_6 membrane K08978 - - 0.000000000000000000000000000000000000000000000001021 183.0
PYH3_k127_6085218_7 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000001094 160.0
PYH3_k127_6085218_8 - - - - 0.000000000000000000002371 99.0
PYH3_k127_6085218_9 Protein of unknown function (DUF2442) - - - 0.000000003148 62.0
PYH3_k127_6152187_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.039e-201 636.0
PYH3_k127_6152187_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 431.0
PYH3_k127_6152187_10 ATPase, P-type K01531 - 3.6.3.2 0.000005769 48.0
PYH3_k127_6152187_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000006606 179.0
PYH3_k127_6152187_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000006662 146.0
PYH3_k127_6152187_4 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000005181 106.0
PYH3_k127_6152187_5 Universal stress protein - - - 0.000000000000000000006202 101.0
PYH3_k127_6152187_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000002179 93.0
PYH3_k127_6152187_7 Cbs domain K04767 - - 0.00000000000000009918 85.0
PYH3_k127_6152187_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000006284 72.0
PYH3_k127_6152187_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000001323 57.0
PYH3_k127_6168191_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002946 278.0
PYH3_k127_6168191_1 cobalamin binding K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000001542 220.0
PYH3_k127_6168191_2 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000167 80.0
PYH3_k127_6217148_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 504.0
PYH3_k127_6217148_1 PFAM dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 462.0
PYH3_k127_6217148_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 391.0
PYH3_k127_6217148_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000001572 145.0
PYH3_k127_6217148_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000001053 122.0
PYH3_k127_6232894_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 424.0
PYH3_k127_6232894_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000167 253.0
PYH3_k127_6232894_2 transglycosylase K08309 - - 0.000000000000000000000000000000000000000000005334 181.0
PYH3_k127_6232894_3 iron-sulfur cluster assembly K07400,K13628,K15724 - - 0.000000000000000000000000006734 115.0
PYH3_k127_6232894_4 RDD family - - - 0.0000000000003761 78.0
PYH3_k127_6232894_5 Major Facilitator Superfamily - - - 0.00000004911 59.0
PYH3_k127_6232894_6 Peptidase family M48 - - - 0.00002868 55.0
PYH3_k127_6241387_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 476.0
PYH3_k127_6241387_1 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000005039 173.0
PYH3_k127_6244702_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.597e-250 792.0
PYH3_k127_6244702_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 484.0
PYH3_k127_6244702_10 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000003419 153.0
PYH3_k127_6244702_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000002402 159.0
PYH3_k127_6244702_12 PFAM cyclic nucleotide-binding K16922 - - 0.0000000000000000000000000000009559 138.0
PYH3_k127_6244702_13 DivIVA protein K04074 - - 0.00000000000000000000006497 104.0
PYH3_k127_6244702_14 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000007673 84.0
PYH3_k127_6244702_15 YGGT family K02221 - - 0.000000000000001174 88.0
PYH3_k127_6244702_16 SNARE associated Golgi protein - - - 0.000000000000002111 84.0
PYH3_k127_6244702_17 DUF167 - - - 0.00000000000008224 77.0
PYH3_k127_6244702_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 471.0
PYH3_k127_6244702_3 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
PYH3_k127_6244702_4 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 388.0
PYH3_k127_6244702_5 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 377.0
PYH3_k127_6244702_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002836 276.0
PYH3_k127_6244702_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000004138 227.0
PYH3_k127_6244702_8 Cupin domain - - - 0.0000000000000000000000000000000000000000000000002488 178.0
PYH3_k127_6244702_9 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000002726 189.0
PYH3_k127_6267346_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 525.0
PYH3_k127_6267346_1 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007683 282.0
PYH3_k127_6267346_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000001432 205.0
PYH3_k127_6267346_3 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000002309 173.0
PYH3_k127_6267346_4 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000001181 165.0
PYH3_k127_6267346_5 Uncharacterized ACR, COG1430 K09005 - - 0.000002652 56.0
PYH3_k127_6267346_6 - - - - 0.00002805 57.0
PYH3_k127_6277118_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 518.0
PYH3_k127_6277118_1 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 322.0
PYH3_k127_6277118_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000001205 186.0
PYH3_k127_6277118_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000003229 111.0
PYH3_k127_6280541_0 Peptidase family M1 domain K08776 - - 6.978e-226 728.0
PYH3_k127_6280541_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 422.0
PYH3_k127_6280541_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000001088 166.0
PYH3_k127_6280541_11 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000001469 166.0
PYH3_k127_6280541_12 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000002721 140.0
PYH3_k127_6280541_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000001161 134.0
PYH3_k127_6280541_14 Major Facilitator Superfamily - - - 0.00000000000000000000000000001771 132.0
PYH3_k127_6280541_15 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000001479 114.0
PYH3_k127_6280541_16 - - - - 0.0000000000000000000000004744 120.0
PYH3_k127_6280541_17 Vitamin B12 dependent methionine synthase, activation domain - - - 0.00000000000000006743 89.0
PYH3_k127_6280541_18 CDGSH-type zinc finger. Function unknown. - - - 0.00000000001501 71.0
PYH3_k127_6280541_19 Sugar (and other) transporter - - - 0.000021 55.0
PYH3_k127_6280541_2 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 391.0
PYH3_k127_6280541_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 340.0
PYH3_k127_6280541_4 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000004036 256.0
PYH3_k127_6280541_5 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000004721 246.0
PYH3_k127_6280541_6 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000007408 241.0
PYH3_k127_6280541_7 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000006899 228.0
PYH3_k127_6280541_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000001152 228.0
PYH3_k127_6280541_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000004114 178.0
PYH3_k127_629474_0 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 355.0
PYH3_k127_629474_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000009174 179.0
PYH3_k127_629474_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000004143 85.0
PYH3_k127_629586_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 2.958e-265 827.0
PYH3_k127_629586_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000003505 211.0
PYH3_k127_629586_2 Polysaccharide deacetylase - - - 0.000002986 50.0
PYH3_k127_6326243_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.2e-218 698.0
PYH3_k127_6326243_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
PYH3_k127_6326243_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 473.0
PYH3_k127_6326243_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 422.0
PYH3_k127_6326243_4 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
PYH3_k127_6326243_5 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000673 233.0
PYH3_k127_6326243_6 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000001378 189.0
PYH3_k127_6326243_7 Enoyl-CoA hydratase K16425 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 - 0.000000000000000000000000000000000000000001829 166.0
PYH3_k127_6326243_8 PFAM histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000001968 147.0
PYH3_k127_6346575_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1216.0
PYH3_k127_6346575_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 430.0
PYH3_k127_6373825_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 340.0
PYH3_k127_6373825_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000125 265.0
PYH3_k127_6373825_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000009717 77.0
PYH3_k127_6373825_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000003053 63.0
PYH3_k127_6373825_4 Belongs to the 'phage' integrase family - - - 0.0003134 46.0
PYH3_k127_6408525_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 489.0
PYH3_k127_6408525_1 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000000000008063 127.0
PYH3_k127_6411525_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 8.695e-228 720.0
PYH3_k127_6411525_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.257e-206 651.0
PYH3_k127_6411525_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 475.0
PYH3_k127_6411525_3 Binding-protein-dependent transport system inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 426.0
PYH3_k127_6411525_4 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 423.0
PYH3_k127_6411525_5 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 398.0
PYH3_k127_6411525_6 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 290.0
PYH3_k127_6411525_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000009862 174.0
PYH3_k127_6411525_8 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000001824 66.0
PYH3_k127_6508573_0 ABC transporter K03701 - - 0.0 1257.0
PYH3_k127_6508573_1 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 479.0
PYH3_k127_6508573_10 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000005208 139.0
PYH3_k127_6508573_12 Acyl dehydratase - - - 0.00000000000000001822 94.0
PYH3_k127_6508573_13 DinB superfamily - - - 0.000000000000004813 81.0
PYH3_k127_6508573_14 N-terminal half of MaoC dehydratase - - - 0.0000001907 63.0
PYH3_k127_6508573_2 Pyruvate kinase, alpha/beta domain K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 423.0
PYH3_k127_6508573_3 amp-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 309.0
PYH3_k127_6508573_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 272.0
PYH3_k127_6508573_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002226 234.0
PYH3_k127_6508573_6 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000001507 218.0
PYH3_k127_6508573_7 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000005985 200.0
PYH3_k127_6508573_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000002027 177.0
PYH3_k127_6508573_9 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000007167 151.0
PYH3_k127_6594085_0 PLD-like domain - - - 4.752e-236 743.0
PYH3_k127_6594085_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 307.0
PYH3_k127_6607746_0 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 523.0
PYH3_k127_6607746_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000001509 119.0
PYH3_k127_6607746_2 Cytochrome c K00406 - - 0.000000001559 64.0
PYH3_k127_6657474_0 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 391.0
PYH3_k127_6657474_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 339.0
PYH3_k127_6657474_10 Putative zinc-finger - - - 0.00000000007654 67.0
PYH3_k127_6657474_11 LysM domain - - - 0.00007202 54.0
PYH3_k127_6657474_2 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 314.0
PYH3_k127_6657474_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000762 282.0
PYH3_k127_6657474_4 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
PYH3_k127_6657474_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000001145 241.0
PYH3_k127_6657474_6 Thioredoxin-like - - - 0.0000000000000000000000000000000001796 139.0
PYH3_k127_6657474_7 Protein conserved in bacteria - - - 0.000000000000000000000000000001255 134.0
PYH3_k127_6657474_8 Pup-like protein K13570 - - 0.000000000000002014 77.0
PYH3_k127_6657474_9 regulatory protein, FmdB family - - - 0.00000000001972 66.0
PYH3_k127_6694668_0 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 494.0
PYH3_k127_6694668_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 414.0
PYH3_k127_6694668_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000002791 230.0
PYH3_k127_6694668_3 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000000000000000000000001204 167.0
PYH3_k127_6721599_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2479.0
PYH3_k127_6721599_1 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.031e-241 753.0
PYH3_k127_6721599_10 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 306.0
PYH3_k127_6721599_11 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002129 280.0
PYH3_k127_6721599_12 COG0583 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000176 266.0
PYH3_k127_6721599_13 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001429 192.0
PYH3_k127_6721599_14 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001257 163.0
PYH3_k127_6721599_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000005941 158.0
PYH3_k127_6721599_16 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000004835 158.0
PYH3_k127_6721599_17 FAD binding domain K11472 - - 0.000000000000000000000002627 108.0
PYH3_k127_6721599_18 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.0000000000000000002133 92.0
PYH3_k127_6721599_19 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000001323 76.0
PYH3_k127_6721599_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 2.941e-231 732.0
PYH3_k127_6721599_20 - - - - 0.0000000000001398 74.0
PYH3_k127_6721599_3 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 539.0
PYH3_k127_6721599_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 461.0
PYH3_k127_6721599_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 439.0
PYH3_k127_6721599_6 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 426.0
PYH3_k127_6721599_7 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 419.0
PYH3_k127_6721599_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 401.0
PYH3_k127_6721599_9 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 308.0
PYH3_k127_6732191_0 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 385.0
PYH3_k127_6732191_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002292 269.0
PYH3_k127_6732191_2 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000007889 50.0
PYH3_k127_6764743_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 560.0
PYH3_k127_6764743_1 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002555 255.0
PYH3_k127_6764743_2 thiamine pyrophosphate protein TPP binding domain protein K01652,K12253 - 2.2.1.6,4.1.1.75 0.00000000000000000000000000000000000000000000000000000000003576 216.0
PYH3_k127_679079_0 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
PYH3_k127_679079_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 310.0
PYH3_k127_679079_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 308.0
PYH3_k127_679079_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
PYH3_k127_679079_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
PYH3_k127_679079_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 317.0
PYH3_k127_679079_6 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001619 225.0
PYH3_k127_679079_7 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000007596 166.0
PYH3_k127_6812234_0 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 608.0
PYH3_k127_6812234_1 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 528.0
PYH3_k127_6812234_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 492.0
PYH3_k127_6812234_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 437.0
PYH3_k127_6812234_4 of the double-stranded beta helix - - - 0.0000000000000000000000000000000000000000000000000000000000000004771 224.0
PYH3_k127_6812234_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000008725 174.0
PYH3_k127_6812234_6 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001553 177.0
PYH3_k127_6812234_7 Arginine repressor, DNA binding domain K03402 - - 0.000000000000000000002162 100.0
PYH3_k127_6860963_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 6.668e-269 859.0
PYH3_k127_6860963_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.321e-211 665.0
PYH3_k127_6860963_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000001052 214.0
PYH3_k127_6860963_11 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000005124 207.0
PYH3_k127_6860963_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000002228 152.0
PYH3_k127_6860963_13 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000000000000005889 111.0
PYH3_k127_6860963_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000007107 123.0
PYH3_k127_6860963_15 - - - - 0.00000709 57.0
PYH3_k127_6860963_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 476.0
PYH3_k127_6860963_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 436.0
PYH3_k127_6860963_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 440.0
PYH3_k127_6860963_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
PYH3_k127_6860963_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000007402 263.0
PYH3_k127_6860963_7 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000002362 239.0
PYH3_k127_6860963_8 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000001728 242.0
PYH3_k127_6860963_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000001659 233.0
PYH3_k127_6870833_0 PFAM AMP-dependent synthetase and ligase K00666 - - 5.242e-299 944.0
PYH3_k127_6876418_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 9.834e-267 830.0
PYH3_k127_6876418_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 445.0
PYH3_k127_6876418_2 rRNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002992 218.0
PYH3_k127_6876418_3 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000003713 209.0
PYH3_k127_6886047_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 554.0
PYH3_k127_6886047_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 444.0
PYH3_k127_6886047_10 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000002926 151.0
PYH3_k127_6886047_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000001897 141.0
PYH3_k127_6886047_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000001678 130.0
PYH3_k127_6886047_13 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000008374 82.0
PYH3_k127_6886047_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 406.0
PYH3_k127_6886047_3 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 387.0
PYH3_k127_6886047_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006734 280.0
PYH3_k127_6886047_5 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003507 230.0
PYH3_k127_6886047_6 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
PYH3_k127_6886047_7 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
PYH3_k127_6886047_8 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000005969 181.0
PYH3_k127_6886047_9 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000002346 156.0
PYH3_k127_6903554_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1155.0
PYH3_k127_6903554_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.073e-214 682.0
PYH3_k127_6903554_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 400.0
PYH3_k127_6903554_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 295.0
PYH3_k127_6903554_4 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008555 262.0
PYH3_k127_6903554_5 protein, possibly involved in aromatic compounds catabolism - - - 0.000002938 59.0
PYH3_k127_6938260_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 477.0
PYH3_k127_6938260_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 395.0
PYH3_k127_6938260_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 293.0
PYH3_k127_6938260_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
PYH3_k127_6938260_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006133 263.0
PYH3_k127_6938260_5 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000009188 194.0
PYH3_k127_6938260_6 transport system periplasmic component K01989 - - 0.00000000000000000000271 98.0
PYH3_k127_6939153_0 Bacterial extracellular solute-binding protein K05813 - - 2.775e-196 622.0
PYH3_k127_6939153_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001354 272.0
PYH3_k127_6955475_0 Peptide ABC transporter substrate-binding protein K02035 - - 3.067e-289 896.0
PYH3_k127_6955475_1 sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 542.0
PYH3_k127_6955475_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 484.0
PYH3_k127_6955475_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 422.0
PYH3_k127_6955475_4 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 382.0
PYH3_k127_6955475_5 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 310.0
PYH3_k127_6955475_6 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
PYH3_k127_6955475_7 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001317 282.0
PYH3_k127_6955475_8 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000001089 240.0
PYH3_k127_6955475_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001889 192.0
PYH3_k127_696910_0 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000000007915 154.0
PYH3_k127_696910_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000007405 132.0
PYH3_k127_696910_2 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000000000000000008485 134.0
PYH3_k127_696910_3 PFAM CBS domain K04767 - - 0.0000000000000000001682 94.0
PYH3_k127_696910_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000002892 55.0
PYH3_k127_6979416_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 469.0
PYH3_k127_6979416_1 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 448.0
PYH3_k127_6979416_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 393.0
PYH3_k127_6979416_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000002354 131.0
PYH3_k127_7010847_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 485.0
PYH3_k127_7010847_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 477.0
PYH3_k127_7010847_10 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 319.0
PYH3_k127_7010847_11 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 307.0
PYH3_k127_7010847_12 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 313.0
PYH3_k127_7010847_13 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007015 275.0
PYH3_k127_7010847_14 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
PYH3_k127_7010847_15 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 262.0
PYH3_k127_7010847_16 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008925 263.0
PYH3_k127_7010847_17 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000252 260.0
PYH3_k127_7010847_18 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000003289 238.0
PYH3_k127_7010847_19 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000001032 248.0
PYH3_k127_7010847_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 463.0
PYH3_k127_7010847_20 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000001216 225.0
PYH3_k127_7010847_21 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000004558 212.0
PYH3_k127_7010847_22 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000153 211.0
PYH3_k127_7010847_23 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000001596 183.0
PYH3_k127_7010847_24 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000008192 169.0
PYH3_k127_7010847_25 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000001631 148.0
PYH3_k127_7010847_26 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000001411 133.0
PYH3_k127_7010847_27 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000006525 137.0
PYH3_k127_7010847_28 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000262 124.0
PYH3_k127_7010847_29 Carboxymuconolactone decarboxylase family - - - 0.00000000000001061 77.0
PYH3_k127_7010847_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 417.0
PYH3_k127_7010847_30 Carboxymuconolactone decarboxylase family - - - 0.0001322 50.0
PYH3_k127_7010847_4 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 377.0
PYH3_k127_7010847_5 NADP-dependent K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 372.0
PYH3_k127_7010847_6 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 363.0
PYH3_k127_7010847_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 362.0
PYH3_k127_7010847_8 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 353.0
PYH3_k127_7010847_9 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 319.0
PYH3_k127_7014328_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1117.0
PYH3_k127_7014328_1 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 437.0
PYH3_k127_7014328_2 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 320.0
PYH3_k127_7014328_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001366 282.0
PYH3_k127_7014328_4 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000149 255.0
PYH3_k127_7014328_5 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000000218 182.0
PYH3_k127_7014328_6 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000001411 119.0
PYH3_k127_7014328_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000006927 93.0
PYH3_k127_7014328_8 Bacterial regulatory proteins, tetR family - - - 0.0000000002107 69.0
PYH3_k127_7028271_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 556.0
PYH3_k127_7028271_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 380.0
PYH3_k127_7028271_10 Thioredoxin-like - - - 0.0000006305 55.0
PYH3_k127_7028271_11 Redoxin K03564 - 1.11.1.15 0.00003408 53.0
PYH3_k127_7028271_2 NMT1 THI5-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 328.0
PYH3_k127_7028271_3 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 313.0
PYH3_k127_7028271_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009883 273.0
PYH3_k127_7028271_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH3_k127_7028271_6 PFAM N-formylglutamate amidohydrolase - - - 0.00000000000000000002324 101.0
PYH3_k127_7028271_7 Thioredoxin-like - - - 0.000000000000008807 78.0
PYH3_k127_7028271_8 Redoxin - - - 0.0000000005121 64.0
PYH3_k127_7028271_9 - - - - 0.00000008327 61.0
PYH3_k127_7031014_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 399.0
PYH3_k127_7031014_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 337.0
PYH3_k127_7031014_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 302.0
PYH3_k127_7031014_3 endonuclease activity - - - 0.00000000000000000000000000000000000000000007274 168.0
PYH3_k127_7031014_4 CopC domain - - - 0.000000000000000000000000000486 126.0
PYH3_k127_7031014_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000001547 114.0
PYH3_k127_7038184_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.729e-268 839.0
PYH3_k127_7038184_1 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 537.0
PYH3_k127_7038184_10 HNH nucleases - - - 0.000000000000000000000001149 113.0
PYH3_k127_7038184_12 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000003597 65.0
PYH3_k127_7038184_13 Methyltransferase domain - - - 0.00000005499 62.0
PYH3_k127_7038184_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 515.0
PYH3_k127_7038184_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 349.0
PYH3_k127_7038184_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
PYH3_k127_7038184_5 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 310.0
PYH3_k127_7038184_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000002486 213.0
PYH3_k127_7038184_7 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000006349 199.0
PYH3_k127_7038184_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000002127 175.0
PYH3_k127_7038184_9 PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 0.000000000000000000000000234 106.0
PYH3_k127_7042343_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 527.0
PYH3_k127_7042343_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 292.0
PYH3_k127_7042343_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000002127 253.0
PYH3_k127_7042343_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
PYH3_k127_7042343_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000002764 242.0
PYH3_k127_7042343_5 Transposase - - - 0.00000000000000001159 97.0
PYH3_k127_7042343_6 - - - - 0.0000000001252 73.0
PYH3_k127_7054035_0 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 435.0
PYH3_k127_7054035_1 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 365.0
PYH3_k127_7054035_2 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 260.0
PYH3_k127_7054035_3 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008021 255.0
PYH3_k127_7054035_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001769 259.0
PYH3_k127_7054035_5 NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000001434 229.0
PYH3_k127_7054035_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000149 152.0
PYH3_k127_7054035_7 PERMEase K06901 - - 0.0000000000000000000000000001051 118.0
PYH3_k127_7054035_9 - - - - 0.00006825 53.0
PYH3_k127_7084700_0 PFAM amidohydrolase K07045 - - 3.202e-196 627.0
PYH3_k127_7084700_1 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 347.0
PYH3_k127_7084700_2 3-isopropylmalate dehydrogenase activity K00052,K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85,1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000001294 282.0
PYH3_k127_7084700_3 Mannose-6-phosphate isomerase - - - 0.000000001735 65.0
PYH3_k127_7116246_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.39e-262 829.0
PYH3_k127_7116246_1 AcrB/AcrD/AcrF family - - - 1.914e-212 675.0
PYH3_k127_7116246_2 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 484.0
PYH3_k127_7116246_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 376.0
PYH3_k127_7116246_4 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000003687 251.0
PYH3_k127_7116246_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000201 112.0
PYH3_k127_7119829_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
PYH3_k127_7119829_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007412 302.0
PYH3_k127_7119829_2 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002792 198.0
PYH3_k127_7119829_3 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000001864 150.0
PYH3_k127_7119829_4 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000442 142.0
PYH3_k127_7119829_5 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000001729 65.0
PYH3_k127_7119829_6 - - - - 0.00000002158 58.0
PYH3_k127_7135762_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 602.0
PYH3_k127_7135762_1 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 314.0
PYH3_k127_7135762_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000001168 198.0
PYH3_k127_7135762_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000001191 147.0
PYH3_k127_7135762_4 Predicted permease - - - 0.000000000000000000000000000000002417 135.0
PYH3_k127_7135762_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000006567 94.0
PYH3_k127_7135762_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082 - 1.1.1.193 0.00000000000000001601 96.0
PYH3_k127_7135762_7 Histidine kinase K01768,K02660,K03406,K07315 - 3.1.3.3,4.6.1.1 0.000000327 63.0
PYH3_k127_7175162_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 590.0
PYH3_k127_7175162_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 460.0
PYH3_k127_7175162_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000004891 156.0
PYH3_k127_7175162_11 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000005855 86.0
PYH3_k127_7175162_12 Phosphoribosyl transferase domain - - - 0.000000000000006509 76.0
PYH3_k127_7175162_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 451.0
PYH3_k127_7175162_3 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 430.0
PYH3_k127_7175162_4 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
PYH3_k127_7175162_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 388.0
PYH3_k127_7175162_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 371.0
PYH3_k127_7175162_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007205 278.0
PYH3_k127_7175162_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000005797 246.0
PYH3_k127_7175162_9 NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000007408 156.0
PYH3_k127_7182000_0 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 560.0
PYH3_k127_7182000_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 468.0
PYH3_k127_7182000_10 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
PYH3_k127_7182000_11 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003561 267.0
PYH3_k127_7182000_12 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000004311 249.0
PYH3_k127_7182000_13 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001613 243.0
PYH3_k127_7182000_14 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000228 243.0
PYH3_k127_7182000_15 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000003712 225.0
PYH3_k127_7182000_16 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000004333 203.0
PYH3_k127_7182000_17 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000001231 161.0
PYH3_k127_7182000_18 ABC transporter K02003 - - 0.000000000000000000000000000000000000001804 149.0
PYH3_k127_7182000_19 EamA-like transporter family - - - 0.0000000000000000000000000000000000002355 153.0
PYH3_k127_7182000_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 452.0
PYH3_k127_7182000_21 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000002096 132.0
PYH3_k127_7182000_22 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000459 112.0
PYH3_k127_7182000_23 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.00000000000000000001141 99.0
PYH3_k127_7182000_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000001405 94.0
PYH3_k127_7182000_25 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000001317 81.0
PYH3_k127_7182000_26 Redoxin - - - 0.0000000000002244 70.0
PYH3_k127_7182000_27 Tetratricopeptide repeat - - - 0.000000000001389 77.0
PYH3_k127_7182000_28 Short repeat of unknown function (DUF308) - - - 0.00000000001439 73.0
PYH3_k127_7182000_29 DinB family - - - 0.0000000006067 65.0
PYH3_k127_7182000_3 ABC-type multidrug transport system ATPase and permease K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 425.0
PYH3_k127_7182000_4 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 400.0
PYH3_k127_7182000_5 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 349.0
PYH3_k127_7182000_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 334.0
PYH3_k127_7182000_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
PYH3_k127_7182000_8 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 293.0
PYH3_k127_7182000_9 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001644 287.0
PYH3_k127_722464_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 327.0
PYH3_k127_722464_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
PYH3_k127_722464_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006707 250.0
PYH3_k127_722464_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000002579 224.0
PYH3_k127_722464_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000005815 97.0
PYH3_k127_722464_5 Glycine-zipper domain - - - 0.000000000001438 68.0
PYH3_k127_722464_6 - - - - 0.000000000002235 74.0
PYH3_k127_722710_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 443.0
PYH3_k127_722710_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 417.0
PYH3_k127_722710_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 315.0
PYH3_k127_722710_3 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 293.0
PYH3_k127_722710_4 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 296.0
PYH3_k127_722710_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000004053 258.0
PYH3_k127_7231716_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.999e-297 932.0
PYH3_k127_7231716_1 DNA polymerase X family K02347,K04477 - - 4.639e-235 741.0
PYH3_k127_7231716_10 Universal stress protein family - - - 0.000000000000000000000006174 109.0
PYH3_k127_7231716_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.001e-217 702.0
PYH3_k127_7231716_3 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 395.0
PYH3_k127_7231716_4 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 294.0
PYH3_k127_7231716_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001693 258.0
PYH3_k127_7231716_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000002664 250.0
PYH3_k127_7231716_7 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000002886 216.0
PYH3_k127_7231716_8 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000003154 218.0
PYH3_k127_7231716_9 GYD domain - - - 0.00000000000000000000000000000006543 131.0
PYH3_k127_725326_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000008285 232.0
PYH3_k127_725326_1 - - - - 0.00001675 56.0
PYH3_k127_725326_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0001861 53.0
PYH3_k127_7260702_0 Methionine synthase K00548 - 2.1.1.13 0.0 1122.0
PYH3_k127_7260702_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 433.0
PYH3_k127_7260702_2 3-carboxyethylcatechol 2,3-dioxygenase activity K05713 - 1.13.11.16 0.0000000000000000000000000000000007714 143.0
PYH3_k127_7290548_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 601.0
PYH3_k127_7290548_1 SNARE-like domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001792 232.0
PYH3_k127_7290548_2 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000003421 201.0
PYH3_k127_7290548_3 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000888 71.0
PYH3_k127_7293437_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 446.0
PYH3_k127_7293437_1 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 389.0
PYH3_k127_7293437_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003971 294.0
PYH3_k127_7295295_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 317.0
PYH3_k127_7295295_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001814 275.0
PYH3_k127_7295295_2 Family 5 K02035 - - 0.0000000000000000000000000000000000000000000000008649 188.0
PYH3_k127_7312922_0 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 621.0
PYH3_k127_7312922_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 336.0
PYH3_k127_7312922_10 Haem-degrading - - - 0.00000001217 62.0
PYH3_k127_7312922_11 Tetratricopeptide repeat - - - 0.0001246 53.0
PYH3_k127_7312922_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 336.0
PYH3_k127_7312922_3 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 305.0
PYH3_k127_7312922_4 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008015 252.0
PYH3_k127_7312922_5 GTP binding K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
PYH3_k127_7312922_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008023 251.0
PYH3_k127_7312922_7 Roadblock/LC7 domain - - - 0.000000000000000000000000001725 119.0
PYH3_k127_7312922_8 Trypsin-like peptidase domain - - - 0.00000000000000006319 94.0
PYH3_k127_7312922_9 PFAM Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.0000000003586 66.0
PYH3_k127_7345046_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 606.0
PYH3_k127_7345046_1 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 302.0
PYH3_k127_7345046_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000001416 139.0
PYH3_k127_7345046_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000307 76.0
PYH3_k127_7345046_4 Belongs to the UPF0312 family - - - 0.000002867 58.0
PYH3_k127_7380060_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.244e-201 637.0
PYH3_k127_7380060_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 471.0
PYH3_k127_7380060_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 413.0
PYH3_k127_7380060_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 409.0
PYH3_k127_7380060_4 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
PYH3_k127_7380060_5 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000009269 165.0
PYH3_k127_7380060_6 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000001765 174.0
PYH3_k127_7380060_7 YMGG-like Gly-zipper - - - 0.0000001569 59.0
PYH3_k127_7412219_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 590.0
PYH3_k127_7412219_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 464.0
PYH3_k127_7412219_2 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
PYH3_k127_7412219_3 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
PYH3_k127_7412219_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000002743 196.0
PYH3_k127_7412219_5 - - - - 0.000000000000000000000000000000000000002489 153.0
PYH3_k127_7412219_6 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000771 126.0
PYH3_k127_7412219_7 quinone binding K12057,K22278 - 3.5.1.104 0.000000000000000000000000000009412 128.0
PYH3_k127_7412219_8 Pfam:DUF385 - - - 0.0000000000000000007368 92.0
PYH3_k127_7412219_9 PFAM Vitamin K epoxide reductase - - - 0.000000000000000007451 85.0
PYH3_k127_742094_0 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 436.0
PYH3_k127_742094_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 429.0
PYH3_k127_742094_10 Adenylate cyclase K01768 - 4.6.1.1 0.000000003675 60.0
PYH3_k127_742094_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 340.0
PYH3_k127_742094_3 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 331.0
PYH3_k127_742094_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 248.0
PYH3_k127_742094_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000001594 235.0
PYH3_k127_742094_6 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000007673 205.0
PYH3_k127_742094_7 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000009341 169.0
PYH3_k127_742094_8 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000002004 150.0
PYH3_k127_742094_9 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000001674 60.0
PYH3_k127_7443162_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000002306 235.0
PYH3_k127_7443162_1 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000001041 78.0
PYH3_k127_7443162_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000002636 57.0
PYH3_k127_7446814_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1086.0
PYH3_k127_7446814_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 8.469e-221 703.0
PYH3_k127_7446814_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 408.0
PYH3_k127_7446814_11 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 398.0
PYH3_k127_7446814_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 396.0
PYH3_k127_7446814_13 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 391.0
PYH3_k127_7446814_14 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 367.0
PYH3_k127_7446814_15 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 376.0
PYH3_k127_7446814_16 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 337.0
PYH3_k127_7446814_17 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 338.0
PYH3_k127_7446814_18 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 323.0
PYH3_k127_7446814_19 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 293.0
PYH3_k127_7446814_2 protein conserved in bacteria K07793 - - 3.359e-218 687.0
PYH3_k127_7446814_20 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000003753 261.0
PYH3_k127_7446814_21 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000001238 243.0
PYH3_k127_7446814_22 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000575 225.0
PYH3_k127_7446814_23 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000008566 222.0
PYH3_k127_7446814_24 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000001195 220.0
PYH3_k127_7446814_25 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000003537 218.0
PYH3_k127_7446814_26 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000007493 217.0
PYH3_k127_7446814_27 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000001088 209.0
PYH3_k127_7446814_28 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000004382 202.0
PYH3_k127_7446814_29 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000004411 211.0
PYH3_k127_7446814_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 516.0
PYH3_k127_7446814_30 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000005893 190.0
PYH3_k127_7446814_31 PFAM Bacterial regulatory proteins, gntR family K05799 - - 0.000000000000000000000000000000000000000000004699 173.0
PYH3_k127_7446814_32 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000001896 160.0
PYH3_k127_7446814_33 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000007202 135.0
PYH3_k127_7446814_34 Smr domain - - - 0.000000000000000000000000000007164 120.0
PYH3_k127_7446814_35 Endoribonuclease L-PSP - - - 0.000000000000000000000000000009934 124.0
PYH3_k127_7446814_36 SnoaL-like domain - - - 0.00000000000000000000000001355 113.0
PYH3_k127_7446814_37 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000007753 94.0
PYH3_k127_7446814_38 - - - - 0.0000001109 62.0
PYH3_k127_7446814_39 - - - - 0.000004518 54.0
PYH3_k127_7446814_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 520.0
PYH3_k127_7446814_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 488.0
PYH3_k127_7446814_6 PFAM extracellular solute-binding protein family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 491.0
PYH3_k127_7446814_7 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 453.0
PYH3_k127_7446814_8 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 434.0
PYH3_k127_7446814_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 431.0
PYH3_k127_7453574_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 1.132e-207 657.0
PYH3_k127_7453574_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 358.0
PYH3_k127_7453574_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000007115 166.0
PYH3_k127_7453574_3 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000001877 156.0
PYH3_k127_7473913_0 Amidohydrolase family - - - 1.483e-288 893.0
PYH3_k127_7473913_1 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 2.658e-238 756.0
PYH3_k127_7473913_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 422.0
PYH3_k127_7473913_11 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 415.0
PYH3_k127_7473913_12 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
PYH3_k127_7473913_13 Rieske [2Fe-2S] domain K21323 - 1.14.13.229,1.14.19.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 377.0
PYH3_k127_7473913_14 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 377.0
PYH3_k127_7473913_15 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 337.0
PYH3_k127_7473913_16 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 339.0
PYH3_k127_7473913_17 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 332.0
PYH3_k127_7473913_18 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 323.0
PYH3_k127_7473913_19 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 324.0
PYH3_k127_7473913_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 3.239e-206 649.0
PYH3_k127_7473913_20 serine-type endopeptidase activity K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 302.0
PYH3_k127_7473913_21 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 319.0
PYH3_k127_7473913_22 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009454 273.0
PYH3_k127_7473913_23 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000957 273.0
PYH3_k127_7473913_24 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000003291 259.0
PYH3_k127_7473913_25 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000216 240.0
PYH3_k127_7473913_26 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000534 234.0
PYH3_k127_7473913_27 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001171 226.0
PYH3_k127_7473913_28 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000007003 226.0
PYH3_k127_7473913_29 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
PYH3_k127_7473913_3 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 627.0
PYH3_k127_7473913_30 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000001226 217.0
PYH3_k127_7473913_31 Low molecular weight phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.00000000000000000000000000000000000000000000000000007329 207.0
PYH3_k127_7473913_32 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000002113 185.0
PYH3_k127_7473913_33 Enoyl-CoA hydratase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000007005 177.0
PYH3_k127_7473913_34 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000002552 151.0
PYH3_k127_7473913_35 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000008756 134.0
PYH3_k127_7473913_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.0000000000000000000000000004049 126.0
PYH3_k127_7473913_37 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000008191 119.0
PYH3_k127_7473913_38 AraC-like ligand binding domain - - - 0.000000000000000000000000114 119.0
PYH3_k127_7473913_39 AraC-like ligand binding domain - - - 0.0000000000000000000003642 109.0
PYH3_k127_7473913_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 589.0
PYH3_k127_7473913_40 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000004365 97.0
PYH3_k127_7473913_41 ABC transporter substrate binding protein K01989 - - 0.000000000000000001522 86.0
PYH3_k127_7473913_42 AhpC/TSA family - - - 0.000000000000000007995 88.0
PYH3_k127_7473913_44 ABC transporter substrate binding protein K01989 - - 0.000000000000003806 80.0
PYH3_k127_7473913_45 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000003201 76.0
PYH3_k127_7473913_48 DinB superfamily - - - 0.00003742 53.0
PYH3_k127_7473913_5 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 566.0
PYH3_k127_7473913_6 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 556.0
PYH3_k127_7473913_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 539.0
PYH3_k127_7473913_8 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 511.0
PYH3_k127_7473913_9 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 458.0
PYH3_k127_74768_0 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 498.0
PYH3_k127_74768_1 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 460.0
PYH3_k127_74768_2 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 400.0
PYH3_k127_74768_3 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 392.0
PYH3_k127_74768_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000001439 128.0
PYH3_k127_74768_5 NMT1-like family K07080 - - 0.000000009908 63.0
PYH3_k127_7500661_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 293.0
PYH3_k127_7500661_1 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005535 282.0
PYH3_k127_7500661_10 Peptidase family M23 - - - 0.000000000001048 76.0
PYH3_k127_7500661_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
PYH3_k127_7500661_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
PYH3_k127_7500661_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000005027 226.0
PYH3_k127_7500661_5 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.0000000000000000000000000000000000000000000000000000007795 199.0
PYH3_k127_7500661_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000004907 188.0
PYH3_k127_7500661_7 Zn peptidase - - - 0.00000000000000000000000000000000000000444 162.0
PYH3_k127_7500661_8 PFAM EamA-like transporter family - - - 0.00000000000000000001983 104.0
PYH3_k127_7500661_9 EamA-like transporter family - - - 0.000000000000000005705 94.0
PYH3_k127_7541583_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 469.0
PYH3_k127_7541583_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 463.0
PYH3_k127_7541583_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 366.0
PYH3_k127_7541583_3 3-hydroxyacyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
PYH3_k127_7541583_4 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 299.0
PYH3_k127_7541583_5 PFAM LrgB family protein - - - 0.000000000000000000000000000000000000000002918 169.0
PYH3_k127_7541583_6 Effector of murein hydrolase LrgA K06518 - - 0.00000000000000000000000001964 114.0
PYH3_k127_7541583_7 PFAM ROSMUCR transcriptional regulator - - - 0.00000000313 69.0
PYH3_k127_7548121_0 Protein of unknown function, DUF255 K06888 - - 1.021e-239 761.0
PYH3_k127_7548121_1 PFAM NAD-dependent epimerase dehydratase - - - 4.001e-226 715.0
PYH3_k127_7548121_10 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 382.0
PYH3_k127_7548121_11 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
PYH3_k127_7548121_12 Peptidase family M28 K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 343.0
PYH3_k127_7548121_13 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 338.0
PYH3_k127_7548121_14 B12 binding domain K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 324.0
PYH3_k127_7548121_15 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 327.0
PYH3_k127_7548121_16 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 310.0
PYH3_k127_7548121_17 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 306.0
PYH3_k127_7548121_18 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002108 269.0
PYH3_k127_7548121_19 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008743 267.0
PYH3_k127_7548121_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 2.524e-199 631.0
PYH3_k127_7548121_20 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
PYH3_k127_7548121_21 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008163 265.0
PYH3_k127_7548121_22 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000009221 256.0
PYH3_k127_7548121_23 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002592 252.0
PYH3_k127_7548121_24 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000003777 231.0
PYH3_k127_7548121_25 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000001419 234.0
PYH3_k127_7548121_26 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005729 225.0
PYH3_k127_7548121_27 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH3_k127_7548121_28 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000001956 214.0
PYH3_k127_7548121_29 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000027 209.0
PYH3_k127_7548121_3 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 592.0
PYH3_k127_7548121_30 - - - - 0.0000000000000000000000000000000000000000000000008686 186.0
PYH3_k127_7548121_31 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000008628 194.0
PYH3_k127_7548121_32 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000009265 181.0
PYH3_k127_7548121_33 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000002724 181.0
PYH3_k127_7548121_34 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000000000000000005707 178.0
PYH3_k127_7548121_35 KR domain - - - 0.0000000000000000000000000000000000000000000005705 175.0
PYH3_k127_7548121_36 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000005325 175.0
PYH3_k127_7548121_37 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000005305 154.0
PYH3_k127_7548121_38 phosphorelay signal transduction system K11443 - - 0.000000000000000000000000000000000002604 156.0
PYH3_k127_7548121_39 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000001983 146.0
PYH3_k127_7548121_4 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 489.0
PYH3_k127_7548121_40 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000266 142.0
PYH3_k127_7548121_41 Predicted membrane protein (DUF2079) - - - 0.0000000000000000000000000000001683 143.0
PYH3_k127_7548121_42 transferase activity, transferring acyl groups K03824,K15520 - 2.3.1.189 0.000000000000000000000000002256 127.0
PYH3_k127_7548121_43 carboxylic ester hydrolase activity - - - 0.00000000000000000000000001363 127.0
PYH3_k127_7548121_44 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000000001894 119.0
PYH3_k127_7548121_45 Desulfoferrodoxin K05919 - 1.15.1.2 0.00000000000000003135 90.0
PYH3_k127_7548121_46 X-Pro dipeptidyl-peptidase (S15 family) K06889,K07397 - - 0.00000000000003002 84.0
PYH3_k127_7548121_47 thiamine biosynthesis protein ThiS K03154 - - 0.0000000002734 64.0
PYH3_k127_7548121_48 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000005869 64.0
PYH3_k127_7548121_49 Carboxymuconolactone decarboxylase family - - - 0.00000007087 61.0
PYH3_k127_7548121_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 498.0
PYH3_k127_7548121_50 - - - - 0.0000001776 59.0
PYH3_k127_7548121_51 - - - - 0.000004978 53.0
PYH3_k127_7548121_52 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.000885 46.0
PYH3_k127_7548121_6 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 471.0
PYH3_k127_7548121_7 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 456.0
PYH3_k127_7548121_8 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 464.0
PYH3_k127_7548121_9 amine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 433.0
PYH3_k127_7569058_0 lipopolysaccharide transport K22110 - - 0.0 1285.0
PYH3_k127_7569058_1 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1275.0
PYH3_k127_7569058_10 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 309.0
PYH3_k127_7569058_11 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
PYH3_k127_7569058_12 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000001079 247.0
PYH3_k127_7569058_13 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000001964 231.0
PYH3_k127_7569058_14 - - - - 0.0000000000000000000000000000000000000000000000015 183.0
PYH3_k127_7569058_15 dehydratase - - - 0.0000000000000000000000000000000000000000000002771 178.0
PYH3_k127_7569058_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0032991,GO:0032993,GO:0043565,GO:0097159,GO:1901363 3.4.21.88 0.0000000000000000000000000000000000000000000153 169.0
PYH3_k127_7569058_17 LemA family K03744 - - 0.0000000000000000000000000000000000000000007028 165.0
PYH3_k127_7569058_18 - - - - 0.000000000000000000000000000000000000000001046 166.0
PYH3_k127_7569058_19 PFAM Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000005087 161.0
PYH3_k127_7569058_2 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.421e-196 624.0
PYH3_k127_7569058_20 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000008277 130.0
PYH3_k127_7569058_21 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000157 117.0
PYH3_k127_7569058_22 - - - - 0.0000000000000006475 88.0
PYH3_k127_7569058_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001608 74.0
PYH3_k127_7569058_24 Glycine-zipper domain - - - 0.00001194 57.0
PYH3_k127_7569058_25 Protein conserved in bacteria - - - 0.00001707 58.0
PYH3_k127_7569058_26 FecR protein - - - 0.00001842 56.0
PYH3_k127_7569058_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 476.0
PYH3_k127_7569058_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 421.0
PYH3_k127_7569058_5 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 383.0
PYH3_k127_7569058_6 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 324.0
PYH3_k127_7569058_7 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 322.0
PYH3_k127_7569058_8 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 313.0
PYH3_k127_7569058_9 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 317.0
PYH3_k127_7588670_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 348.0
PYH3_k127_7588670_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007286 260.0
PYH3_k127_7588670_2 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000000001066 226.0
PYH3_k127_7588670_3 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000007351 135.0
PYH3_k127_7588670_4 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.0000000000000000000000005451 111.0
PYH3_k127_7627003_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 335.0
PYH3_k127_7627003_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000008037 239.0
PYH3_k127_7627003_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000003855 151.0
PYH3_k127_7638426_0 COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000002431 143.0
PYH3_k127_7638426_2 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.0000000000000000000000003736 112.0
PYH3_k127_7638426_3 membrane K15977 - - 0.00000000000001697 81.0
PYH3_k127_7638426_4 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000001281 74.0
PYH3_k127_767056_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 393.0
PYH3_k127_767056_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 318.0
PYH3_k127_767056_2 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000406 259.0
PYH3_k127_767056_3 Binding-protein-dependent transport system inner membrane component K15771 - - 0.00000000000000000000000000000000000000000000000000000002519 209.0
PYH3_k127_767056_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000009177 201.0
PYH3_k127_767056_5 ABC-type sugar transport system, permease component K02026,K17323 - - 0.000000000000000000000000000000000000000000000000000003299 213.0
PYH3_k127_767056_6 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000297 182.0
PYH3_k127_767056_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000001558 144.0
PYH3_k127_767056_8 DinB superfamily - - - 0.000000000000001787 83.0
PYH3_k127_767056_9 L-aminopeptidase D-esterase K18572 - - 0.0000000000003581 74.0
PYH3_k127_7678845_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 539.0
PYH3_k127_7678845_1 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 509.0
PYH3_k127_7678845_2 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 474.0
PYH3_k127_7678845_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 412.0
PYH3_k127_7678845_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 378.0
PYH3_k127_7678845_5 PFAM type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000332 294.0
PYH3_k127_7678845_6 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000002929 242.0
PYH3_k127_7678845_7 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000003591 191.0
PYH3_k127_7678845_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000001562 186.0
PYH3_k127_7678845_9 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000009801 183.0
PYH3_k127_7702667_0 cytochrome P450 K00493,K21257 - 1.14.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 398.0
PYH3_k127_7702667_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 348.0
PYH3_k127_7702667_2 Belongs to the UbiD family K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 336.0
PYH3_k127_7702667_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001427 267.0
PYH3_k127_7702667_4 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000001325 213.0
PYH3_k127_7702667_5 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000001146 132.0
PYH3_k127_774785_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 448.0
PYH3_k127_774785_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 311.0
PYH3_k127_774785_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 309.0
PYH3_k127_774785_3 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000001881 154.0
PYH3_k127_774785_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000001494 145.0
PYH3_k127_774785_5 Glycosyl transferase, family 2 K07011,K20444 - - 0.0000000000000000000000001945 116.0
PYH3_k127_774785_6 - - - - 0.00000000000000000000006537 111.0
PYH3_k127_774785_7 Mycolic acid cyclopropane synthetase - - - 0.000000000004622 69.0
PYH3_k127_7747941_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 352.0
PYH3_k127_7747941_1 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 342.0
PYH3_k127_7747941_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003147 284.0
PYH3_k127_7747941_3 Luciferase-like monooxygenase - - - 0.0006191 46.0
PYH3_k127_7794824_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.72e-196 630.0
PYH3_k127_7794824_1 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 477.0
PYH3_k127_7794824_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 393.0
PYH3_k127_7794824_3 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 325.0
PYH3_k127_7794824_4 Wzy family polymerase, exosortase system type 1 associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 303.0
PYH3_k127_7794824_5 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000007206 216.0
PYH3_k127_7794824_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000008622 195.0
PYH3_k127_7794824_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003026 183.0
PYH3_k127_7794824_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000005572 152.0
PYH3_k127_7795114_0 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 297.0
PYH3_k127_7795114_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
PYH3_k127_7795114_2 - - - - 0.00000001949 63.0
PYH3_k127_7795114_3 YMGG-like Gly-zipper - - - 0.0000585 47.0
PYH3_k127_7811527_0 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 466.0
PYH3_k127_7811527_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 385.0
PYH3_k127_7811527_2 UDP binding domain K00012,K00066,K02472,K02474,K13015 - 1.1.1.132,1.1.1.136,1.1.1.22,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 356.0
PYH3_k127_7811527_3 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 349.0
PYH3_k127_7811527_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 349.0
PYH3_k127_7811527_5 Glycosyl transferases group 1 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 338.0
PYH3_k127_7811527_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 308.0
PYH3_k127_7811527_7 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000005746 220.0
PYH3_k127_7811527_8 Glycosyl transferases group 1 K16703 - - 0.00000000000000000000000000002266 131.0
PYH3_k127_7811527_9 transmembrane protein EpsH - - - 0.00006402 53.0
PYH3_k127_7820874_0 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 399.0
PYH3_k127_7820874_1 ABC transporter K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 358.0
PYH3_k127_7820874_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 335.0
PYH3_k127_7820874_3 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 325.0
PYH3_k127_7820874_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 300.0
PYH3_k127_7820874_5 Desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000001957 205.0
PYH3_k127_7820874_6 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000005773 124.0
PYH3_k127_7820874_7 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00000000000000000000000000007752 136.0
PYH3_k127_7824599_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 1.152e-251 788.0
PYH3_k127_7824599_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 570.0
PYH3_k127_7824599_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 516.0
PYH3_k127_7824599_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
PYH3_k127_7824599_4 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000004228 230.0
PYH3_k127_7824599_5 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000000002755 195.0
PYH3_k127_7824599_6 - - - - 0.000000000001003 72.0
PYH3_k127_7851805_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 5.664e-292 902.0
PYH3_k127_7851805_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 524.0
PYH3_k127_7851805_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006431 255.0
PYH3_k127_7851805_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000006885 195.0
PYH3_k127_7851805_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000726 96.0
PYH3_k127_7851805_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00004705 51.0
PYH3_k127_7858245_0 PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 604.0
PYH3_k127_7858245_1 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 297.0
PYH3_k127_7858245_10 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000001287 136.0
PYH3_k127_7858245_11 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000006366 130.0
PYH3_k127_7858245_12 dehydrogenases and related proteins - - - 0.000000000000000000000000004708 124.0
PYH3_k127_7858245_13 Methyltransferase FkbM domain - - - 0.0000000000000000000018 106.0
PYH3_k127_7858245_14 Polysaccharide biosynthesis protein - - - 0.00000000000000000002696 105.0
PYH3_k127_7858245_15 Glycosyl transferases group 1 - - - 0.0000000000000003973 93.0
PYH3_k127_7858245_16 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.0000000004739 73.0
PYH3_k127_7858245_17 PFAM Methyltransferase type 11 - - - 0.000000003901 67.0
PYH3_k127_7858245_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000459 269.0
PYH3_k127_7858245_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006886 278.0
PYH3_k127_7858245_4 - - - - 0.0000000000000000000000000000000000000000000000000000000002188 226.0
PYH3_k127_7858245_5 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000002283 213.0
PYH3_k127_7858245_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000001715 207.0
PYH3_k127_7858245_7 methyltransferase K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000001917 194.0
PYH3_k127_7858245_8 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000002453 156.0
PYH3_k127_7858245_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000003061 157.0
PYH3_k127_7873414_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 1.387e-217 692.0
PYH3_k127_7873414_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 576.0
PYH3_k127_7873414_2 Transglycosylase K05365,K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 565.0
PYH3_k127_7873414_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 451.0
PYH3_k127_7873414_4 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 362.0
PYH3_k127_7873414_5 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 329.0
PYH3_k127_7873414_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 290.0
PYH3_k127_7873414_7 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000001354 136.0
PYH3_k127_7873414_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000001292 96.0
PYH3_k127_7922731_0 N-terminal half of MaoC dehydratase - - - 5.909e-208 650.0
PYH3_k127_7922731_1 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 494.0
PYH3_k127_7922731_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 413.0
PYH3_k127_7922731_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 360.0
PYH3_k127_7922731_4 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000006925 238.0
PYH3_k127_7922731_5 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.0000000000000000000000000000000000000000000001344 169.0
PYH3_k127_7923831_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.632e-196 629.0
PYH3_k127_7923831_1 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 347.0
PYH3_k127_7923831_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000002894 198.0
PYH3_k127_7923831_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000002161 143.0
PYH3_k127_7923831_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000342 71.0
PYH3_k127_7923831_5 TonB C terminal K03832 - - 0.000000000001788 74.0
PYH3_k127_7923831_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000008385 50.0
PYH3_k127_7976246_0 Sulfate permease family K03321 - - 3.107e-218 713.0
PYH3_k127_7976246_1 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 291.0
PYH3_k127_7976246_2 acyl-CoA dehydrogenase K09456,K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000001442 255.0
PYH3_k127_7976246_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000005677 182.0
PYH3_k127_7979219_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 406.0
PYH3_k127_7979219_1 DJ-1/PfpI family K18199 - 4.2.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 284.0
PYH3_k127_7979219_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000007056 188.0
PYH3_k127_8119968_0 heat shock protein 70 K04043,K04044 - - 7.183e-198 634.0
PYH3_k127_8119968_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 569.0
PYH3_k127_8119968_10 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564 - 0.0000000000000000000000000000002158 126.0
PYH3_k127_8119968_11 DnaJ molecular chaperone homology domain K04082 - - 0.000000000000000000000000005224 120.0
PYH3_k127_8119968_12 Iron-sulphur cluster assembly - - - 0.000000000000000000000582 102.0
PYH3_k127_8119968_13 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000008328 100.0
PYH3_k127_8119968_14 NifU-like N terminal domain K04488 - - 0.0000000000000000393 87.0
PYH3_k127_8119968_16 glutaredoxin-like protein, YruB-family - - - 0.00000000001761 66.0
PYH3_k127_8119968_17 TPR repeat - - - 0.000000006763 68.0
PYH3_k127_8119968_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 533.0
PYH3_k127_8119968_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 460.0
PYH3_k127_8119968_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000476 261.0
PYH3_k127_8119968_5 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 258.0
PYH3_k127_8119968_6 oxidoreductase activity K07114,K16257 - - 0.00000000000000000000000000000000000000000000000000000000000000000001553 267.0
PYH3_k127_8119968_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000003473 225.0
PYH3_k127_8119968_8 Transcriptional regulator - - - 0.000000000000000000000000000000000004749 142.0
PYH3_k127_8119968_9 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000001128 148.0
PYH3_k127_8210_0 Copper amine oxidase, enzyme domain K00276 - 1.4.3.21 4.021e-274 865.0
PYH3_k127_8210_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 474.0
PYH3_k127_8210_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000006639 170.0
PYH3_k127_8210_3 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000001005 162.0
PYH3_k127_8210_4 transmembrane transport - - - 0.00000000000000000000000000000003663 130.0
PYH3_k127_8210_5 amino acid adenylation domain protein - - - 0.0000005342 57.0
PYH3_k127_8215024_0 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 521.0
PYH3_k127_8215024_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 304.0
PYH3_k127_8215024_2 YceG-like family K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001264 255.0
PYH3_k127_8215024_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000009859 135.0
PYH3_k127_8340730_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
PYH3_k127_8340730_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 490.0
PYH3_k127_8340730_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000002542 145.0
PYH3_k127_8340730_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000001536 113.0
PYH3_k127_8340730_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000002831 106.0
PYH3_k127_8340730_13 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000002612 86.0
PYH3_k127_8340730_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 372.0
PYH3_k127_8340730_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 384.0
PYH3_k127_8340730_4 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 370.0
PYH3_k127_8340730_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 319.0
PYH3_k127_8340730_6 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 297.0
PYH3_k127_8340730_7 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000003592 271.0
PYH3_k127_8340730_8 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001335 242.0
PYH3_k127_8340730_9 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000003883 226.0
PYH3_k127_834308_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.894e-246 768.0
PYH3_k127_834308_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 2.664e-243 760.0
PYH3_k127_834308_10 PAS domain - - - 0.00000000000000000000000000000000000000000007169 182.0
PYH3_k127_834308_11 oxidoreductase - - - 0.00000000000000000000000000000000000000002854 163.0
PYH3_k127_834308_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000007321 136.0
PYH3_k127_834308_13 phosphate regulon transcriptional regulatory protein PhoB K07657,K07659 - - 0.0000000000000000000000000000001259 129.0
PYH3_k127_834308_14 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000001736 114.0
PYH3_k127_834308_15 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000004461 105.0
PYH3_k127_834308_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000005692 105.0
PYH3_k127_834308_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000005212 79.0
PYH3_k127_834308_18 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000003683 70.0
PYH3_k127_834308_19 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000004634 57.0
PYH3_k127_834308_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
PYH3_k127_834308_20 Protein of unknown function (DUF507) K09804 - - 0.0003955 50.0
PYH3_k127_834308_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 361.0
PYH3_k127_834308_4 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
PYH3_k127_834308_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 318.0
PYH3_k127_834308_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 248.0
PYH3_k127_834308_7 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003776 247.0
PYH3_k127_834308_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000004771 237.0
PYH3_k127_834308_9 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000004668 189.0
PYH3_k127_836578_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000006836 217.0
PYH3_k127_836578_1 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000002559 182.0
PYH3_k127_836578_2 Cupin domain - - - 0.0000000000000000000000000000000000000008306 153.0
PYH3_k127_836578_3 General secretory system II, protein E domain protein K02652 - - 0.000000000000000009357 86.0
PYH3_k127_836578_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000002189 91.0
PYH3_k127_836578_5 Glutaredoxin K03676,K06191 - - 0.00000002158 58.0
PYH3_k127_8383055_0 indolepyruvate ferredoxin oxidoreductase activity K00175,K04090 - 1.2.7.11,1.2.7.3,1.2.7.8 0.0 1297.0
PYH3_k127_8383055_1 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 361.0
PYH3_k127_8383055_10 PFAM NLP P60 protein K20742,K21471 - 3.4.14.13 0.0002572 51.0
PYH3_k127_8383055_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 316.0
PYH3_k127_8383055_3 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 294.0
PYH3_k127_8383055_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002495 274.0
PYH3_k127_8383055_5 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000001865 211.0
PYH3_k127_8383055_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001473 203.0
PYH3_k127_8383055_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000001618 196.0
PYH3_k127_8383055_8 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000002621 164.0
PYH3_k127_8383055_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000007513 180.0
PYH3_k127_8384716_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 441.0
PYH3_k127_8384716_1 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000476 225.0
PYH3_k127_8384716_2 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000004086 60.0
PYH3_k127_8441977_0 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000001228 197.0
PYH3_k127_8441977_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000002817 186.0
PYH3_k127_8441977_2 PFAM UspA domain protein - - - 0.00000000000000000000002033 106.0
PYH3_k127_8441977_3 Belongs to the universal stress protein A family - - - 0.0000000000000000000007207 102.0
PYH3_k127_8441977_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000003047 87.0
PYH3_k127_8441977_5 Universal stress protein - - - 0.0000000000000000232 87.0
PYH3_k127_8445807_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 467.0
PYH3_k127_8445807_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000005626 165.0
PYH3_k127_8445807_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000003708 125.0
PYH3_k127_8449999_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.184e-271 854.0
PYH3_k127_8449999_1 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 434.0
PYH3_k127_8449999_2 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000001182 234.0
PYH3_k127_8449999_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000006747 204.0
PYH3_k127_8449999_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000004472 174.0
PYH3_k127_8449999_5 protein conserved in bacteria - - - 0.000002191 59.0
PYH3_k127_8459001_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 343.0
PYH3_k127_8488998_0 Large extracellular alpha-helical protein K06894 - - 0.0 1846.0
PYH3_k127_8488998_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 366.0
PYH3_k127_8488998_2 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000004389 225.0
PYH3_k127_8488998_3 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000008601 198.0
PYH3_k127_8496868_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.853e-244 764.0
PYH3_k127_8496868_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 522.0
PYH3_k127_8496868_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 419.0
PYH3_k127_8496868_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000165 197.0
PYH3_k127_8496868_4 - - - - 0.000000000000000000000000000000000000000002584 163.0
PYH3_k127_8496868_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000005826 148.0
PYH3_k127_8496868_6 Cell division protein FtsQ K03589 - - 0.00000121 56.0
PYH3_k127_8514154_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 351.0
PYH3_k127_8514154_1 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 359.0
PYH3_k127_8514154_2 Bifunctional protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001825 266.0
PYH3_k127_8514154_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000000000000000000002785 252.0
PYH3_k127_8514154_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000002936 191.0
PYH3_k127_8524644_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 565.0
PYH3_k127_8524644_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 543.0
PYH3_k127_8524644_10 alcohol dehydrogenase - - - 0.0000000000000000000000000000000001437 142.0
PYH3_k127_8524644_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000002516 94.0
PYH3_k127_8524644_13 protein conserved in bacteria K11904 - - 0.00000000000007685 77.0
PYH3_k127_8524644_2 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 370.0
PYH3_k127_8524644_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 360.0
PYH3_k127_8524644_4 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 341.0
PYH3_k127_8524644_5 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001398 289.0
PYH3_k127_8524644_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000019 250.0
PYH3_k127_8524644_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K13483,K20446 - 1.17.1.5,1.2.5.3 0.00000000000000000000000000000000000000000000895 178.0
PYH3_k127_8524644_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000001767 153.0
PYH3_k127_8528351_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
PYH3_k127_8528351_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 429.0
PYH3_k127_8528351_2 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000003794 215.0
PYH3_k127_8528351_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000002371 200.0
PYH3_k127_8528351_4 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000122 59.0
PYH3_k127_8528351_5 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000007937 54.0
PYH3_k127_8538803_0 Glutamate aspartate transport system permease protein GltJ K02029,K10003 - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
PYH3_k127_8538803_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000001124 202.0
PYH3_k127_8538803_2 Alpha beta hydrolase - - - 0.00000001954 64.0
PYH3_k127_8538803_3 Alpha/beta hydrolase family - GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0019233,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046839,GO:0046872,GO:0050877,GO:0050896,GO:0065007,GO:0065008,GO:0071704 - 0.000002892 55.0
PYH3_k127_8578455_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
PYH3_k127_8578455_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 350.0
PYH3_k127_8578455_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 340.0
PYH3_k127_8578455_3 P-loop containing region of AAA domain K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001644 287.0
PYH3_k127_8578455_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000004471 241.0
PYH3_k127_8578455_5 ATPases associated with a variety of cellular activities K01996 - - 0.000002069 58.0
PYH3_k127_8595945_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 475.0
PYH3_k127_8595945_1 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000003438 236.0
PYH3_k127_8595945_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000008423 216.0
PYH3_k127_8595945_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000009543 217.0
PYH3_k127_8595945_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000004022 163.0
PYH3_k127_8603885_0 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 404.0
PYH3_k127_8603885_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 391.0
PYH3_k127_8603885_2 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000008549 191.0
PYH3_k127_8603885_3 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000001896 184.0
PYH3_k127_8603885_4 MaoC like domain - - - 0.00000000000000000000000000000000000001884 157.0
PYH3_k127_8603885_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000307 45.0
PYH3_k127_8608423_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002388 292.0
PYH3_k127_8608423_1 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000007272 245.0
PYH3_k127_8608423_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000002789 198.0
PYH3_k127_8608423_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000003406 62.0
PYH3_k127_8638053_0 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 332.0
PYH3_k127_8638053_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 299.0
PYH3_k127_8638053_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 302.0
PYH3_k127_8638053_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 311.0
PYH3_k127_8638053_4 Methyltransferase fkbm family - - - 0.00000000000000000000000000000000000000000000000000001825 193.0
PYH3_k127_8638053_5 Glyoxalase-like domain - - - 0.0000000000000000000000005054 116.0
PYH3_k127_8640600_0 AMP-binding enzyme C-terminal domain - - - 1.634e-210 672.0
PYH3_k127_8640600_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 455.0
PYH3_k127_8640600_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 413.0
PYH3_k127_8640600_3 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 412.0
PYH3_k127_8640600_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000123 271.0
PYH3_k127_8657568_0 GTP-binding protein TypA K06207 - - 7.566e-263 827.0
PYH3_k127_8657568_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.857e-207 670.0
PYH3_k127_8657568_10 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000001404 235.0
PYH3_k127_8657568_11 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000001492 246.0
PYH3_k127_8657568_12 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001607 217.0
PYH3_k127_8657568_13 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000001035 195.0
PYH3_k127_8657568_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000369 188.0
PYH3_k127_8657568_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000006918 187.0
PYH3_k127_8657568_16 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000003457 181.0
PYH3_k127_8657568_17 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000007682 124.0
PYH3_k127_8657568_18 PAS PAC sensor hybrid histidine kinase - - - 0.000000000000000000000006821 107.0
PYH3_k127_8657568_19 PFAM regulatory protein, LysR K02019 - - 0.000000000000001048 83.0
PYH3_k127_8657568_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 520.0
PYH3_k127_8657568_20 - K09794 - - 0.0000007615 54.0
PYH3_k127_8657568_3 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 471.0
PYH3_k127_8657568_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 440.0
PYH3_k127_8657568_5 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 359.0
PYH3_k127_8657568_6 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 355.0
PYH3_k127_8657568_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 347.0
PYH3_k127_8657568_8 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 315.0
PYH3_k127_8657568_9 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 301.0
PYH3_k127_8688514_0 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 509.0
PYH3_k127_8688514_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 432.0
PYH3_k127_8688514_2 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 344.0
PYH3_k127_8688514_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000001297 229.0
PYH3_k127_8688514_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000001044 133.0
PYH3_k127_8690258_0 PFAM amidohydrolase K07045 - - 2.882e-202 634.0
PYH3_k127_8690258_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 592.0
PYH3_k127_8690258_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000008169 172.0
PYH3_k127_8690258_11 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000001708 168.0
PYH3_k127_8690258_12 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000001184 139.0
PYH3_k127_8690258_13 lactate metabolic process - - - 0.00000000000000000000000000000111 134.0
PYH3_k127_8690258_14 cytidylyl-transferase K00983,K21749 - 2.7.7.43,2.7.7.92 0.0000000000003611 76.0
PYH3_k127_8690258_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 489.0
PYH3_k127_8690258_3 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 457.0
PYH3_k127_8690258_4 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 374.0
PYH3_k127_8690258_5 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 368.0
PYH3_k127_8690258_6 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 326.0
PYH3_k127_8690258_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003493 262.0
PYH3_k127_8690258_8 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004105 242.0
PYH3_k127_8690258_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000005158 199.0
PYH3_k127_8702297_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.026e-280 875.0
PYH3_k127_8702297_1 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 443.0
PYH3_k127_8702297_10 Tetratricopeptide repeat - - - 0.0000009825 61.0
PYH3_k127_8702297_11 FecR protein - - - 0.0000691 56.0
PYH3_k127_8702297_12 Protein conserved in bacteria - - - 0.0004772 53.0
PYH3_k127_8702297_2 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005436 267.0
PYH3_k127_8702297_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000001048 127.0
PYH3_k127_8702297_4 Catalyzes the reduction of tatronate semialdehyde to D- glycerate K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000001091 130.0
PYH3_k127_8702297_5 histidine kinase A domain protein - - - 0.0000000000000000000000000000007995 130.0
PYH3_k127_8702297_6 RNA recognition motif - - - 0.0000000000000000000002663 101.0
PYH3_k127_8702297_7 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.00000000000002268 85.0
PYH3_k127_8702297_8 OsmC-like protein - - - 0.000000000001661 74.0
PYH3_k127_8702297_9 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000001896 66.0
PYH3_k127_876357_0 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000005828 228.0
PYH3_k127_876357_1 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000002524 225.0
PYH3_k127_876357_2 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000000000000000000000000000000000000001921 187.0
PYH3_k127_876357_3 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000007363 196.0
PYH3_k127_876357_4 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000002962 164.0
PYH3_k127_876357_5 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000002225 144.0
PYH3_k127_876357_6 arsenate reductase K00537 - 1.20.4.1 0.0000006007 57.0
PYH3_k127_8769088_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 4.898e-237 736.0
PYH3_k127_8769088_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000001055 221.0
PYH3_k127_8769088_3 Transposase IS116/IS110/IS902 family - - - 0.000000000000001302 87.0
PYH3_k127_8769088_5 PFAM Glycosyl transferase, group 1 K19424 - - 0.0001954 50.0
PYH3_k127_8784186_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 602.0
PYH3_k127_8784186_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 398.0
PYH3_k127_8784186_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002693 246.0
PYH3_k127_8784186_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000002152 226.0
PYH3_k127_8784186_4 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000002127 198.0
PYH3_k127_8784186_5 RNA-binding protein - - - 0.000000000000000000000002836 106.0
PYH3_k127_8842142_0 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 411.0
PYH3_k127_8842142_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 283.0
PYH3_k127_8842142_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000006796 167.0
PYH3_k127_8842142_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000001635 133.0
PYH3_k127_8901572_0 PFAM amidohydrolase K07045 - - 4.628e-205 642.0
PYH3_k127_8901572_1 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000005577 197.0
PYH3_k127_8901572_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000006322 199.0
PYH3_k127_8901572_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000001344 169.0
PYH3_k127_8901572_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000003329 111.0
PYH3_k127_8932955_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 560.0
PYH3_k127_8932955_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 370.0
PYH3_k127_8932955_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001094 287.0
PYH3_k127_8932955_3 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000007842 225.0
PYH3_k127_8932955_4 Methylmalonyl-CoA mutase K01848,K20906 - 5.4.99.2,5.4.99.64 0.000000000007392 66.0
PYH3_k127_8962170_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 6.656e-315 975.0
PYH3_k127_8962170_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 421.0
PYH3_k127_8962170_10 Luciferase-like monooxygenase - - - 0.0004649 49.0
PYH3_k127_8962170_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 300.0
PYH3_k127_8962170_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004644 274.0
PYH3_k127_8962170_4 PFAM thiamine pyrophosphate protein domain protein TPP-binding K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000001336 239.0
PYH3_k127_8962170_5 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000009685 231.0
PYH3_k127_8962170_6 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000003261 203.0
PYH3_k127_8962170_7 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000003468 145.0
PYH3_k127_8962170_9 - - - - 0.000003302 53.0
PYH3_k127_8964076_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 407.0
PYH3_k127_8964076_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 342.0
PYH3_k127_8964076_2 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 323.0
PYH3_k127_8964076_3 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000001847 136.0
PYH3_k127_8964076_4 hydroperoxide reductase activity - - - 0.000000000000000000000000000006602 128.0
PYH3_k127_8964076_5 Pkd domain containing protein - - - 0.00000000000000000000000000004134 128.0
PYH3_k127_8964076_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000001825 102.0
PYH3_k127_8964076_7 Aminotransferase K00812,K14267 - 2.6.1.1,2.6.1.17 0.0000000000000000000001949 107.0
PYH3_k127_8964076_8 STAS domain K04749 - - 0.000000000000001323 80.0
PYH3_k127_8964076_9 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.000000001609 68.0
PYH3_k127_9046656_0 4-hydroxyphenylacetate K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 520.0
PYH3_k127_9046656_1 branched-chain amino acid transport system, permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 406.0
PYH3_k127_9046656_10 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000005926 216.0
PYH3_k127_9046656_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000008455 207.0
PYH3_k127_9046656_12 Amidohydrolase - - - 0.000000000000000000000000002801 113.0
PYH3_k127_9046656_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000004888 95.0
PYH3_k127_9046656_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 386.0
PYH3_k127_9046656_3 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 341.0
PYH3_k127_9046656_4 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 345.0
PYH3_k127_9046656_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 310.0
PYH3_k127_9046656_6 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 291.0
PYH3_k127_9046656_7 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002148 278.0
PYH3_k127_9046656_8 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
PYH3_k127_9046656_9 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006138 267.0
PYH3_k127_9125199_0 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000001408 283.0
PYH3_k127_9125199_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000003816 189.0
PYH3_k127_9125199_2 Putative regulatory protein - - - 0.000000000000000000000000000000000001081 143.0
PYH3_k127_9125199_3 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000006991 115.0
PYH3_k127_9125199_4 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00007118 52.0
PYH3_k127_9156951_0 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 574.0
PYH3_k127_9156951_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 467.0
PYH3_k127_9156951_10 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000002038 148.0
PYH3_k127_9156951_11 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000002694 132.0
PYH3_k127_9156951_12 Cupredoxin-like domain - - - 0.0000000000000000002024 92.0
PYH3_k127_9156951_13 PFAM YCII-related domain K09780 - - 0.0000000004681 68.0
PYH3_k127_9156951_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 439.0
PYH3_k127_9156951_3 Serine hydrolase (FSH1) K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003345 276.0
PYH3_k127_9156951_4 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005235 261.0
PYH3_k127_9156951_5 Inositol monophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001026 244.0
PYH3_k127_9156951_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000008949 199.0
PYH3_k127_9156951_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000000000000000000001632 192.0
PYH3_k127_9156951_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000448 164.0
PYH3_k127_9156951_9 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000004097 156.0
PYH3_k127_9180105_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 323.0
PYH3_k127_9180105_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003866 258.0
PYH3_k127_9180105_2 TIGR00255 family - - - 0.00000000000000000000015 105.0
PYH3_k127_9180105_3 NMT1-like family K02051,K15553 - - 0.0001148 54.0
PYH3_k127_918833_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1299.0
PYH3_k127_918833_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1047.0
PYH3_k127_918833_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 373.0
PYH3_k127_918833_11 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 310.0
PYH3_k127_918833_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
PYH3_k127_918833_13 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 290.0
PYH3_k127_918833_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005674 268.0
PYH3_k127_918833_15 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000122 263.0
PYH3_k127_918833_16 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000003325 239.0
PYH3_k127_918833_17 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001558 214.0
PYH3_k127_918833_18 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000002444 188.0
PYH3_k127_918833_19 Polymer-forming cytoskeletal - - - 0.0000000000000000000002154 102.0
PYH3_k127_918833_2 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1030.0
PYH3_k127_918833_20 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000005979 107.0
PYH3_k127_918833_21 PAP2 superfamily - - - 0.00000000000000006304 86.0
PYH3_k127_918833_22 PAP2 superfamily - - - 0.0000000008562 66.0
PYH3_k127_918833_23 protein transport across the cell outer membrane K02453,K03219 - - 0.00002353 55.0
PYH3_k127_918833_24 protein trimerization - - - 0.0007773 51.0
PYH3_k127_918833_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.627e-213 679.0
PYH3_k127_918833_4 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 569.0
PYH3_k127_918833_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 549.0
PYH3_k127_918833_6 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 512.0
PYH3_k127_918833_7 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 490.0
PYH3_k127_918833_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 421.0
PYH3_k127_918833_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 415.0
PYH3_k127_9258831_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
PYH3_k127_9258831_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003176 281.0
PYH3_k127_9258831_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000006487 156.0
PYH3_k127_9258831_3 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000005177 102.0
PYH3_k127_9258831_4 - - - - 0.000000000000004493 79.0
PYH3_k127_9258831_5 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00001359 48.0
PYH3_k127_9318568_0 AMP-binding enzyme C-terminal domain K00666 - - 1.167e-261 819.0
PYH3_k127_9318568_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 524.0
PYH3_k127_9318568_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000001002 201.0
PYH3_k127_9318568_11 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000002641 193.0
PYH3_k127_9318568_12 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000006812 151.0
PYH3_k127_9318568_13 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000397 138.0
PYH3_k127_9318568_14 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000009953 102.0
PYH3_k127_9318568_15 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000005948 63.0
PYH3_k127_9318568_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 351.0
PYH3_k127_9318568_3 PFAM Acetamidase Formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 310.0
PYH3_k127_9318568_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 306.0
PYH3_k127_9318568_5 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001099 275.0
PYH3_k127_9318568_6 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005021 259.0
PYH3_k127_9318568_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009307 269.0
PYH3_k127_9318568_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001781 229.0
PYH3_k127_9318568_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001601 229.0
PYH3_k127_9318911_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 378.0
PYH3_k127_9318911_1 MmgE/PrpD family - - - 0.000025 48.0
PYH3_k127_9323516_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000002401 73.0
PYH3_k127_9323516_1 Electron transfer flavoprotein K03521 - - 0.00000005591 64.0
PYH3_k127_9323516_2 FAD binding domain K21401 - 1.3.99.38 0.0004424 53.0
PYH3_k127_9331569_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 488.0
PYH3_k127_9331569_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 494.0
PYH3_k127_9331569_2 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
PYH3_k127_9331569_3 Taurine catabolism dioxygenase TauD, TfdA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 339.0
PYH3_k127_9331569_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
PYH3_k127_9331569_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000002125 145.0
PYH3_k127_9331569_6 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000000000006067 122.0
PYH3_k127_9331569_7 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000001487 124.0
PYH3_k127_9331569_8 RF-1 domain K15034 - - 0.0000000000000000000000005166 108.0
PYH3_k127_9331569_9 Cytochrome c7 and related cytochrome c - - - 0.0000000000006276 82.0
PYH3_k127_9338996_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 452.0
PYH3_k127_9338996_1 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.00000000000000000000000000000000000000000000385 174.0
PYH3_k127_9356785_0 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 364.0
PYH3_k127_9356785_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000006168 236.0
PYH3_k127_9356785_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000007135 224.0
PYH3_k127_9356785_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000003967 83.0
PYH3_k127_9366139_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1084.0
PYH3_k127_9366139_1 Beta-lactamase - - - 4.539e-203 658.0
PYH3_k127_9366139_2 negative regulation of protein lipidation K19294 - - 9.874e-201 633.0
PYH3_k127_9366139_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 430.0
PYH3_k127_9366139_4 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 362.0
PYH3_k127_9366139_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
PYH3_k127_9366139_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003979 257.0
PYH3_k127_9366139_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009183 247.0
PYH3_k127_9366139_9 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.0000000000000000000000000000000007966 142.0
PYH3_k127_9390314_0 Drug exporters of the RND superfamily K06994 - - 3.214e-227 726.0
PYH3_k127_9390314_1 Carboxyl transferase domain - - - 8.408e-209 671.0
PYH3_k127_9390314_10 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 351.0
PYH3_k127_9390314_11 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 351.0
PYH3_k127_9390314_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 336.0
PYH3_k127_9390314_13 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
PYH3_k127_9390314_14 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 347.0
PYH3_k127_9390314_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004926 277.0
PYH3_k127_9390314_16 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 272.0
PYH3_k127_9390314_17 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
PYH3_k127_9390314_18 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001045 245.0
PYH3_k127_9390314_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000003699 246.0
PYH3_k127_9390314_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 9.564e-199 630.0
PYH3_k127_9390314_20 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
PYH3_k127_9390314_21 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000005327 256.0
PYH3_k127_9390314_22 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000009722 231.0
PYH3_k127_9390314_23 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000214 242.0
PYH3_k127_9390314_24 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000003032 230.0
PYH3_k127_9390314_25 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000003526 210.0
PYH3_k127_9390314_26 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000001121 212.0
PYH3_k127_9390314_27 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000003091 198.0
PYH3_k127_9390314_28 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000001681 173.0
PYH3_k127_9390314_29 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000003463 181.0
PYH3_k127_9390314_3 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 550.0
PYH3_k127_9390314_30 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000001223 145.0
PYH3_k127_9390314_31 DinB superfamily K07552 - - 0.000000000000000000000000000001723 129.0
PYH3_k127_9390314_33 Biotin-lipoyl like - - - 0.000000000000000004221 86.0
PYH3_k127_9390314_34 Belongs to the UPF0312 family - - - 0.0000000009277 68.0
PYH3_k127_9390314_35 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000001239 62.0
PYH3_k127_9390314_36 Helix-turn-helix domain - - - 0.00004956 48.0
PYH3_k127_9390314_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 496.0
PYH3_k127_9390314_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 489.0
PYH3_k127_9390314_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 377.0
PYH3_k127_9390314_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 374.0
PYH3_k127_9390314_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 366.0
PYH3_k127_9390314_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 353.0
PYH3_k127_9409754_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1140.0
PYH3_k127_9409754_1 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1093.0
PYH3_k127_9409754_2 Belongs to the phosphoglycerate kinase family K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 369.0
PYH3_k127_9409754_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 331.0
PYH3_k127_9409754_4 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000003076 148.0
PYH3_k127_9409754_5 IMP dehydrogenase activity K04767 - - 0.000000000000000002117 92.0
PYH3_k127_9466122_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
PYH3_k127_9466122_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
PYH3_k127_9466122_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000384 216.0
PYH3_k127_9466122_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000239 196.0
PYH3_k127_9482932_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000009438 236.0
PYH3_k127_9482932_1 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000003024 196.0
PYH3_k127_9482932_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.00000000000000000000000000000000000000008826 163.0
PYH3_k127_9482932_3 OsmC-like protein K06889,K07397 - - 0.000000000000002055 78.0
PYH3_k127_9482932_4 Lrp/AsnC ligand binding domain - - - 0.000000009825 67.0
PYH3_k127_9482932_5 OsmC-like protein K06889,K07397 - - 0.00000002676 57.0
PYH3_k127_9482932_6 Phosphate acyltransferases - - - 0.0000417 51.0
PYH3_k127_9503386_0 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 333.0
PYH3_k127_9503386_1 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 308.0
PYH3_k127_9503386_2 metallopeptidase activity K03592 - - 0.00000000000000000000000000000000000000000000000000000000006721 207.0
PYH3_k127_9504782_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 397.0
PYH3_k127_9504782_1 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
PYH3_k127_9504782_2 Binding-protein-dependent transport system inner membrane component K02025,K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001387 256.0
PYH3_k127_9504782_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000004259 231.0
PYH3_k127_9504782_4 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000004472 191.0
PYH3_k127_9504782_5 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000006461 186.0
PYH3_k127_9505297_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 1.293e-233 744.0
PYH3_k127_9505297_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003719 237.0
PYH3_k127_9505297_2 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000003575 188.0
PYH3_k127_9505297_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000004731 175.0
PYH3_k127_9505297_4 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000001472 140.0
PYH3_k127_9505297_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001193 144.0
PYH3_k127_9505297_6 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000004545 139.0
PYH3_k127_9505297_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000003046 121.0
PYH3_k127_9505297_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000002197 108.0
PYH3_k127_9505297_9 Protein of unknown function (DUF2889) - - - 0.00000004017 65.0
PYH3_k127_9537031_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 484.0
PYH3_k127_9537031_1 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 426.0
PYH3_k127_9537031_2 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000007584 218.0
PYH3_k127_9537031_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000002891 117.0
PYH3_k127_9546128_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.116e-279 869.0
PYH3_k127_9546128_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 506.0
PYH3_k127_9546128_2 CoA-transferase family III K07544,K07749 - 2.8.3.15,2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 431.0
PYH3_k127_9546128_3 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 360.0
PYH3_k127_9546128_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 305.0
PYH3_k127_9546128_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003182 290.0
PYH3_k127_9546128_6 Phosphate acyltransferases - - - 0.00000000000414 76.0
PYH3_k127_9657750_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 7.818e-220 728.0
PYH3_k127_9657750_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 297.0
PYH3_k127_9657750_2 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
PYH3_k127_9657750_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000002662 254.0
PYH3_k127_9657750_4 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000001959 230.0
PYH3_k127_9657750_5 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001765 214.0
PYH3_k127_9657750_6 - - - - 0.0000000000000000000000000000000000000000000000004863 183.0
PYH3_k127_9660850_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 417.0
PYH3_k127_9660850_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 425.0
PYH3_k127_9660850_2 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007265 282.0
PYH3_k127_9660850_3 GntR family transcriptional regulator K03486,K03710 - - 0.0000000000000000000000000691 112.0
PYH3_k127_9660850_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000009562 108.0
PYH3_k127_9677062_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.365e-241 763.0
PYH3_k127_9677062_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 2.386e-225 737.0
PYH3_k127_9677062_10 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 297.0
PYH3_k127_9677062_11 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000008093 231.0
PYH3_k127_9677062_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000001251 160.0
PYH3_k127_9677062_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000001876 128.0
PYH3_k127_9677062_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000001984 112.0
PYH3_k127_9677062_15 Regulatory protein, FmdB family - - - 0.0000000000000001237 85.0
PYH3_k127_9677062_16 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.000000000008023 74.0
PYH3_k127_9677062_17 YtxH-like protein - - - 0.000000004317 61.0
PYH3_k127_9677062_18 cAMP biosynthetic process K03765 - - 0.000000571 61.0
PYH3_k127_9677062_19 Evidence 5 No homology to any previously reported sequences K03765 - - 0.000001836 58.0
PYH3_k127_9677062_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 480.0
PYH3_k127_9677062_3 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 458.0
PYH3_k127_9677062_4 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 440.0
PYH3_k127_9677062_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 424.0
PYH3_k127_9677062_6 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 404.0
PYH3_k127_9677062_7 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 379.0
PYH3_k127_9677062_8 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 336.0
PYH3_k127_9677062_9 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 335.0
PYH3_k127_9680830_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.337e-277 870.0
PYH3_k127_9680830_1 AMP-binding enzyme K01897 - 6.2.1.3 1.034e-207 663.0
PYH3_k127_9680830_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 438.0
PYH3_k127_9680830_11 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 436.0
PYH3_k127_9680830_12 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 399.0
PYH3_k127_9680830_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 398.0
PYH3_k127_9680830_14 Branched-chain amino acid transport K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 391.0
PYH3_k127_9680830_15 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 400.0
PYH3_k127_9680830_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 374.0
PYH3_k127_9680830_17 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 370.0
PYH3_k127_9680830_18 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 346.0
PYH3_k127_9680830_19 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000002468 171.0
PYH3_k127_9680830_2 Periplasmic binding protein domain K01999 - - 3.347e-195 616.0
PYH3_k127_9680830_20 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000005734 168.0
PYH3_k127_9680830_21 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000004483 147.0
PYH3_k127_9680830_22 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000002261 132.0
PYH3_k127_9680830_23 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000002474 122.0
PYH3_k127_9680830_3 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 581.0
PYH3_k127_9680830_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 535.0
PYH3_k127_9680830_5 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 492.0
PYH3_k127_9680830_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 475.0
PYH3_k127_9680830_7 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 475.0
PYH3_k127_9680830_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 440.0
PYH3_k127_9680830_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 440.0
PYH3_k127_969490_0 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 444.0
PYH3_k127_969490_1 Belongs to the TtcA family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 349.0
PYH3_k127_969490_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000001053 235.0
PYH3_k127_969490_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000001035 126.0
PYH3_k127_969490_4 Beta-ketoacyl synthase, N-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000001618 120.0
PYH3_k127_969490_5 thiamine diphosphate biosynthetic process K03154 - - 0.00000000003584 70.0
PYH3_k127_969490_7 Protein of unknown function (DUF1569) - - - 0.000002113 57.0
PYH3_k127_970362_0 COG3209 Rhs family protein - - - 9.864e-269 890.0
PYH3_k127_970362_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.271e-236 753.0
PYH3_k127_970362_10 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000002703 191.0
PYH3_k127_970362_11 COG3209 Rhs family protein - - - 0.00000000000000000000000000001966 139.0
PYH3_k127_970362_14 Methionine biosynthesis protein MetW K00574 - 2.1.1.79 0.000001322 60.0
PYH3_k127_970362_15 Chemotaxis sensory transducer K03406 - - 0.0000112 58.0
PYH3_k127_970362_2 thiamine transport K02011 - - 4.294e-235 744.0
PYH3_k127_970362_3 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 525.0
PYH3_k127_970362_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 411.0
PYH3_k127_970362_5 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 387.0
PYH3_k127_970362_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 335.0
PYH3_k127_970362_7 Methionine biosynthesis protein MetW K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 322.0
PYH3_k127_970362_8 IPT/TIG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007568 249.0
PYH3_k127_970362_9 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000001957 233.0
PYH3_k127_970493_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 515.0
PYH3_k127_970493_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 445.0
PYH3_k127_970493_10 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K03606 - - 0.000000000549 60.0
PYH3_k127_970493_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 346.0
PYH3_k127_970493_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 317.0
PYH3_k127_970493_4 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
PYH3_k127_970493_5 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000397 153.0
PYH3_k127_970493_6 Sigma-70 region 2 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000006803 145.0
PYH3_k127_970493_7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000003672 138.0
PYH3_k127_970493_8 O-Antigen ligase K18814 - - 0.0000000000000000000003949 109.0
PYH3_k127_970493_9 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000001721 102.0
PYH3_k127_9716091_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 565.0
PYH3_k127_9716091_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 511.0
PYH3_k127_9716091_2 CoA-transferase family III K07544,K07749 - 2.8.3.15,2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 398.0
PYH3_k127_9716091_3 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002711 275.0
PYH3_k127_9716091_4 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000002331 216.0
PYH3_k127_9716091_5 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000004219 68.0
PYH3_k127_993124_0 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 345.0
PYH3_k127_993124_1 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003257 234.0
PYH3_k127_993124_2 PFAM MOSC domain - - - 0.000000000000000000000000000000004037 144.0