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Overview

ID MAG03252
Name PYH3_bin.66
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum JAUVQV01
Class JAUVQV01
Order
Family
Genus
Species
Assembly information
Completeness (%) 88.29
Contamination (%) 1.67
GC content (%) 65.0
N50 (bp) 13,966
Genome size (bp) 2,245,168

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1977

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1098843_0 Helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 484.0
PYH3_k127_1098843_1 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 323.0
PYH3_k127_1098843_2 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000002027 264.0
PYH3_k127_1098843_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000005095 143.0
PYH3_k127_1098843_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000007112 97.0
PYH3_k127_1098843_5 TIGRFAM regulatory protein, FmdB - - - 0.0000000000004221 74.0
PYH3_k127_1266897_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 452.0
PYH3_k127_1266897_1 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 311.0
PYH3_k127_1266897_2 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000355 184.0
PYH3_k127_1266897_3 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000007237 184.0
PYH3_k127_1266897_4 polysaccharide biosynthetic process - - - 0.000005903 57.0
PYH3_k127_1347328_0 Belongs to the ClpA ClpB family K03696 - - 2.892e-263 824.0
PYH3_k127_1347328_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 524.0
PYH3_k127_1347328_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 514.0
PYH3_k127_1347328_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 306.0
PYH3_k127_1347328_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000006199 214.0
PYH3_k127_1347328_5 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000008586 111.0
PYH3_k127_1347328_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000139 52.0
PYH3_k127_1347328_7 - - - - 0.00008506 49.0
PYH3_k127_1347328_8 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0001986 54.0
PYH3_k127_1359470_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 507.0
PYH3_k127_1359470_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 433.0
PYH3_k127_1359470_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 387.0
PYH3_k127_1359470_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 316.0
PYH3_k127_1359470_4 QueT transporter K16928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001146 255.0
PYH3_k127_1359470_5 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000001102 217.0
PYH3_k127_1359470_6 - - - - 0.0000000000000000000000000000000000000000002722 171.0
PYH3_k127_1359470_7 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.000000000000000000000000000000000000305 155.0
PYH3_k127_1359470_8 Belongs to the 'phage' integrase family - - - 0.000000000000002961 77.0
PYH3_k127_1381846_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 393.0
PYH3_k127_1381846_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 345.0
PYH3_k127_1381846_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000008691 189.0
PYH3_k127_1381846_11 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000164 167.0
PYH3_k127_1381846_12 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000003512 161.0
PYH3_k127_1381846_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000008022 93.0
PYH3_k127_1381846_14 - - - - 0.0006963 48.0
PYH3_k127_1381846_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 338.0
PYH3_k127_1381846_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 325.0
PYH3_k127_1381846_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 290.0
PYH3_k127_1381846_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
PYH3_k127_1381846_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007637 279.0
PYH3_k127_1381846_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
PYH3_k127_1381846_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000003595 213.0
PYH3_k127_1381846_9 FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000004221 190.0
PYH3_k127_1408028_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.742e-306 953.0
PYH3_k127_1408028_1 Acyl-CoA synthetase (NDP forming) K09181 - - 7.182e-215 688.0
PYH3_k127_1408028_10 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001259 262.0
PYH3_k127_1408028_11 Cytidylate kinase-like family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000526 246.0
PYH3_k127_1408028_12 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000003432 251.0
PYH3_k127_1408028_13 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000001858 222.0
PYH3_k127_1408028_14 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000003546 217.0
PYH3_k127_1408028_15 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000736 192.0
PYH3_k127_1408028_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000001043 171.0
PYH3_k127_1408028_17 Rhomboid family - - - 0.000000000000000000000000000000000000000002673 170.0
PYH3_k127_1408028_18 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000005158 140.0
PYH3_k127_1408028_19 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000001385 132.0
PYH3_k127_1408028_2 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 2.763e-203 670.0
PYH3_k127_1408028_20 Glycosyl transferase family 41 K09667 - 2.4.1.255 0.000000000000000000000002925 119.0
PYH3_k127_1408028_21 anaerobic respiration - - - 0.000000000000000000001203 106.0
PYH3_k127_1408028_22 biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000001305 86.0
PYH3_k127_1408028_23 Thioredoxin domain - - - 0.00000000000000336 77.0
PYH3_k127_1408028_24 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000001654 78.0
PYH3_k127_1408028_25 TonB C terminal K03646,K03832 - - 0.000000005768 67.0
PYH3_k127_1408028_26 Alternative locus ID - - - 0.0000005474 60.0
PYH3_k127_1408028_3 acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 608.0
PYH3_k127_1408028_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 539.0
PYH3_k127_1408028_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 370.0
PYH3_k127_1408028_6 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 298.0
PYH3_k127_1408028_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 281.0
PYH3_k127_1408028_8 DRTGG domain protein K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003872 271.0
PYH3_k127_1408028_9 thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001222 264.0
PYH3_k127_1489635_0 Pyridoxal-phosphate dependent enzyme K05396,K17950 - 4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 404.0
PYH3_k127_1489635_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 413.0
PYH3_k127_1489635_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000001071 179.0
PYH3_k127_1489635_11 LUD domain - - - 0.0000000000000000000000000000000000004755 149.0
PYH3_k127_1489635_12 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000004893 88.0
PYH3_k127_1489635_13 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000004467 84.0
PYH3_k127_1489635_14 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001063 74.0
PYH3_k127_1489635_15 TOBE domain - - - 0.0000000000003057 72.0
PYH3_k127_1489635_16 - - - - 0.00000000002844 77.0
PYH3_k127_1489635_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.000447 42.0
PYH3_k127_1489635_2 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 332.0
PYH3_k127_1489635_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 303.0
PYH3_k127_1489635_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002989 301.0
PYH3_k127_1489635_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000007474 241.0
PYH3_k127_1489635_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000459 222.0
PYH3_k127_1489635_7 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
PYH3_k127_1489635_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000001615 198.0
PYH3_k127_1489635_9 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000000000007997 173.0
PYH3_k127_150841_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.208e-284 899.0
PYH3_k127_150841_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.769e-275 865.0
PYH3_k127_150841_10 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.0000000000000000001616 94.0
PYH3_k127_150841_11 - - - - 0.000000000000000003362 97.0
PYH3_k127_150841_2 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 552.0
PYH3_k127_150841_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 486.0
PYH3_k127_150841_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
PYH3_k127_150841_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 330.0
PYH3_k127_150841_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000003675 218.0
PYH3_k127_150841_7 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000008951 199.0
PYH3_k127_150841_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000001487 124.0
PYH3_k127_150841_9 Methyltransferase domain protein - - - 0.0000000000000000000002229 112.0
PYH3_k127_1573071_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 456.0
PYH3_k127_1573071_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 342.0
PYH3_k127_1573071_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006614 271.0
PYH3_k127_1573071_3 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000001694 145.0
PYH3_k127_1645366_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1137.0
PYH3_k127_1645366_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 450.0
PYH3_k127_1645366_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000000000000003915 96.0
PYH3_k127_1645366_2 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 381.0
PYH3_k127_1645366_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 386.0
PYH3_k127_1645366_4 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 355.0
PYH3_k127_1645366_5 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000003465 235.0
PYH3_k127_1645366_6 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000007436 214.0
PYH3_k127_1645366_7 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000000000002829 204.0
PYH3_k127_1645366_8 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000003212 202.0
PYH3_k127_1645366_9 phosphorelay signal transduction system - - - 0.0000000000000000000000001541 119.0
PYH3_k127_1668053_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 395.0
PYH3_k127_1668053_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 320.0
PYH3_k127_1668053_10 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000004509 76.0
PYH3_k127_1668053_11 - - - - 0.000000001736 72.0
PYH3_k127_1668053_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000008204 57.0
PYH3_k127_1668053_13 NHL repeat containing protein - - - 0.000008721 60.0
PYH3_k127_1668053_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005091 285.0
PYH3_k127_1668053_3 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000008892 159.0
PYH3_k127_1668053_4 PAS fold - - - 0.0000000000000000000000000000000000000003868 167.0
PYH3_k127_1668053_5 Nitroreductase family - - - 0.0000000000000000000000000000000000006604 146.0
PYH3_k127_1668053_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000172 141.0
PYH3_k127_1668053_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000004793 108.0
PYH3_k127_1668053_8 Smr domain K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.000000000000000000000003565 113.0
PYH3_k127_1668053_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000009368 86.0
PYH3_k127_1729786_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 391.0
PYH3_k127_1729786_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001075 286.0
PYH3_k127_1729786_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 260.0
PYH3_k127_1729786_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000003676 199.0
PYH3_k127_1729786_4 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000008396 152.0
PYH3_k127_1729786_5 - - - - 0.00000000000004076 86.0
PYH3_k127_1729786_7 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K15342 - - 0.0008835 45.0
PYH3_k127_1747898_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 304.0
PYH3_k127_1747898_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
PYH3_k127_1747898_2 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000000001071 129.0
PYH3_k127_1747898_3 peptidase - - - 0.000000000000000000000000006293 124.0
PYH3_k127_1747898_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000004761 53.0
PYH3_k127_1747898_5 - - - - 0.00001082 53.0
PYH3_k127_1760079_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 481.0
PYH3_k127_1760079_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 419.0
PYH3_k127_1760079_11 Late competence development protein ComFB K02241 - - 0.0005426 49.0
PYH3_k127_1760079_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 295.0
PYH3_k127_1760079_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000001719 209.0
PYH3_k127_1760079_4 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000009175 169.0
PYH3_k127_1760079_6 cell wall binding repeat 2 - - - 0.00000000000000000006194 106.0
PYH3_k127_1760079_7 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000002857 89.0
PYH3_k127_1760079_8 cellulase activity - - - 0.0000000000001422 85.0
PYH3_k127_1760079_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000002231 62.0
PYH3_k127_178442_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 360.0
PYH3_k127_178442_2 Thioredoxin-like - - - 0.0000000000005183 75.0
PYH3_k127_178442_3 Member of the two-component regulatory system HssS HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity) K02483 - - 0.000003206 57.0
PYH3_k127_178442_4 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00001037 59.0
PYH3_k127_1800794_0 Chaperone of endosialidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 389.0
PYH3_k127_1800794_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000005884 175.0
PYH3_k127_1800794_2 oligosaccharyl transferase activity - - - 0.000000000000000000000000000001603 138.0
PYH3_k127_1800794_3 oligosaccharyl transferase activity - - - 0.0000000000000000000000000703 123.0
PYH3_k127_1800794_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000001567 119.0
PYH3_k127_1800794_5 Carboxypeptidase regulatory-like domain - - - 0.0000000004703 74.0
PYH3_k127_1840116_0 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 475.0
PYH3_k127_1840116_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 351.0
PYH3_k127_1840116_2 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000213 299.0
PYH3_k127_1840116_3 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000007842 225.0
PYH3_k127_1840116_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000005378 213.0
PYH3_k127_2054525_0 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 582.0
PYH3_k127_2054525_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 429.0
PYH3_k127_2054525_10 oxidoreductase activity - - - 0.0002154 52.0
PYH3_k127_2054525_2 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 402.0
PYH3_k127_2054525_3 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 394.0
PYH3_k127_2054525_4 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 357.0
PYH3_k127_2054525_5 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 334.0
PYH3_k127_2054525_6 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000005856 167.0
PYH3_k127_2054525_7 membrane K08972 - - 0.0000000000000000000009623 99.0
PYH3_k127_2054525_8 YacP-like NYN domain K06962 - - 0.000000000001211 78.0
PYH3_k127_2054525_9 PFAM TOBE domain - - - 0.000000000005559 68.0
PYH3_k127_2122815_0 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000003438 171.0
PYH3_k127_2122815_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000001113 126.0
PYH3_k127_2122815_2 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.00000000000000000000000001371 116.0
PYH3_k127_2122815_3 Tetratricopeptide repeat - - - 0.0000000007689 67.0
PYH3_k127_2132601_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1161.0
PYH3_k127_2132601_1 PFAM Radical SAM K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 347.0
PYH3_k127_2132601_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000001745 170.0
PYH3_k127_2132601_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000001473 123.0
PYH3_k127_2132601_4 self proteolysis - - - 0.0000000000000000000000000000376 123.0
PYH3_k127_2280731_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
PYH3_k127_2280731_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
PYH3_k127_2280731_2 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002178 239.0
PYH3_k127_2280731_3 PFAM PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000001801 145.0
PYH3_k127_2280731_4 PFAM ADP-ribosylation factor family K06883 - - 0.000000000001972 79.0
PYH3_k127_2280731_5 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000005537 60.0
PYH3_k127_2280731_6 Thiopurine S-methyltransferase (TPMT) - - - 0.0001753 53.0
PYH3_k127_2303049_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 335.0
PYH3_k127_2303049_1 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000179 126.0
PYH3_k127_2303049_2 Calcineurin-like phosphoesterase - - - 0.00000008511 62.0
PYH3_k127_2394232_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1052.0
PYH3_k127_2394232_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.089e-305 944.0
PYH3_k127_2394232_10 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 543.0
PYH3_k127_2394232_11 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 538.0
PYH3_k127_2394232_12 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 520.0
PYH3_k127_2394232_13 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 491.0
PYH3_k127_2394232_14 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 476.0
PYH3_k127_2394232_15 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 423.0
PYH3_k127_2394232_16 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 411.0
PYH3_k127_2394232_17 denitrification pathway K02569,K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 376.0
PYH3_k127_2394232_18 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 331.0
PYH3_k127_2394232_19 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 323.0
PYH3_k127_2394232_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 2.013e-253 795.0
PYH3_k127_2394232_20 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 297.0
PYH3_k127_2394232_21 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 258.0
PYH3_k127_2394232_22 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000241 262.0
PYH3_k127_2394232_23 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000003653 242.0
PYH3_k127_2394232_24 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000006472 234.0
PYH3_k127_2394232_25 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000006323 236.0
PYH3_k127_2394232_26 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000001382 239.0
PYH3_k127_2394232_27 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000004794 224.0
PYH3_k127_2394232_28 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000003437 208.0
PYH3_k127_2394232_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000292 199.0
PYH3_k127_2394232_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.963e-208 661.0
PYH3_k127_2394232_30 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000003962 203.0
PYH3_k127_2394232_31 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000002005 195.0
PYH3_k127_2394232_32 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000003284 175.0
PYH3_k127_2394232_33 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000001953 171.0
PYH3_k127_2394232_34 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000002945 171.0
PYH3_k127_2394232_35 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000006439 170.0
PYH3_k127_2394232_36 AIR carboxylase K01588 - 5.4.99.18 0.00000000000000000000000000000000000000003469 156.0
PYH3_k127_2394232_37 - - - - 0.00000000000000000000000000000000000006461 155.0
PYH3_k127_2394232_38 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000316 141.0
PYH3_k127_2394232_39 - - - - 0.0000000000000000000000000000000488 132.0
PYH3_k127_2394232_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.001e-196 628.0
PYH3_k127_2394232_40 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000004542 120.0
PYH3_k127_2394232_41 - - - - 0.000000000000000000000000001095 114.0
PYH3_k127_2394232_42 Fibronectin type 3 domain - - - 0.000000000000000000000003387 117.0
PYH3_k127_2394232_43 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000005722 106.0
PYH3_k127_2394232_45 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000243 94.0
PYH3_k127_2394232_46 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000003793 83.0
PYH3_k127_2394232_47 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000004023 87.0
PYH3_k127_2394232_48 Lipopolysaccharide-assembly - - - 0.000000000001389 75.0
PYH3_k127_2394232_49 Necessary for formate dehydrogenase activity K02380 - - 0.000000000002365 68.0
PYH3_k127_2394232_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.328e-195 621.0
PYH3_k127_2394232_50 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000001155 73.0
PYH3_k127_2394232_51 response regulator K11444 - 2.7.7.65 0.000000001327 72.0
PYH3_k127_2394232_52 - K09794 - - 0.0000002853 55.0
PYH3_k127_2394232_53 DNA polymerase III (delta' subunit) K02340 - 2.7.7.7 0.000002047 60.0
PYH3_k127_2394232_54 Domain of unknown function (DUF4390) - - - 0.000003045 57.0
PYH3_k127_2394232_55 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000009288 53.0
PYH3_k127_2394232_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 591.0
PYH3_k127_2394232_7 PAS domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 604.0
PYH3_k127_2394232_8 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 592.0
PYH3_k127_2394232_9 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 556.0
PYH3_k127_2412355_0 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 449.0
PYH3_k127_2412355_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001297 283.0
PYH3_k127_2412355_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001632 268.0
PYH3_k127_2412355_3 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000005213 201.0
PYH3_k127_2412355_4 Dimerisation domain - - - 0.00000000000000000002005 96.0
PYH3_k127_2452656_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.082e-302 938.0
PYH3_k127_2452656_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003222 270.0
PYH3_k127_2452656_2 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000003385 220.0
PYH3_k127_2452656_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000001363 175.0
PYH3_k127_2452656_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000001569 135.0
PYH3_k127_2452656_5 - - - - 0.0000000000000000000000000007946 131.0
PYH3_k127_2458141_0 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 464.0
PYH3_k127_2458141_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 450.0
PYH3_k127_2458141_10 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000004744 136.0
PYH3_k127_2458141_11 GIY-YIG catalytic domain K07461 - - 0.00000000000000001051 87.0
PYH3_k127_2458141_12 COG0784 FOG CheY-like receiver - - - 0.0000000214 67.0
PYH3_k127_2458141_13 S-layer homology domain - - - 0.0000002402 60.0
PYH3_k127_2458141_14 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0001701 52.0
PYH3_k127_2458141_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 376.0
PYH3_k127_2458141_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 319.0
PYH3_k127_2458141_4 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000006754 238.0
PYH3_k127_2458141_5 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
PYH3_k127_2458141_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000007036 211.0
PYH3_k127_2458141_7 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000002261 173.0
PYH3_k127_2458141_8 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000002267 152.0
PYH3_k127_2458141_9 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000006261 131.0
PYH3_k127_2463155_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000007228 102.0
PYH3_k127_2497228_0 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 468.0
PYH3_k127_2497228_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 449.0
PYH3_k127_2497228_10 heat shock protein binding - - - 0.0000004488 63.0
PYH3_k127_2497228_2 Ribosomal protein L11 methyltransferase (PrmA) K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
PYH3_k127_2497228_3 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000002583 196.0
PYH3_k127_2497228_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000003813 188.0
PYH3_k127_2497228_5 - - - - 0.000000000000000000000000000000000000000008915 167.0
PYH3_k127_2497228_6 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000002447 105.0
PYH3_k127_2497228_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000004252 68.0
PYH3_k127_2497228_8 Histidine kinase - - - 0.0000001974 63.0
PYH3_k127_2497228_9 Methyltransferase domain K14369 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249 2.1.1.254 0.0000002414 61.0
PYH3_k127_2503805_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 351.0
PYH3_k127_2503805_1 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.000000000000000000000000000000000000000000612 158.0
PYH3_k127_2503805_10 outer membrane protein A K03286 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 - 0.000000006994 66.0
PYH3_k127_2503805_11 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000723 63.0
PYH3_k127_2503805_12 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00002281 51.0
PYH3_k127_2503805_13 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001479 46.0
PYH3_k127_2503805_14 - - - - 0.0007058 43.0
PYH3_k127_2503805_2 - - - - 0.00000000000000000000000000000000000000004228 156.0
PYH3_k127_2503805_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.00000000000000000129 93.0
PYH3_k127_2503805_6 oligosaccharyl transferase activity - - - 0.00000000000000000218 100.0
PYH3_k127_2503805_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000001291 73.0
PYH3_k127_2503805_8 Hep Hag repeat protein - - - 0.000000000006749 78.0
PYH3_k127_2503805_9 Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000002833 73.0
PYH3_k127_2586300_0 Ceramidase - - - 0.0000000000000000000000000000000000000000000000000000001316 206.0
PYH3_k127_2586300_1 DinB family - - - 0.000000000000000000000000000000000000000000000004044 180.0
PYH3_k127_2586300_2 oligosaccharyl transferase activity - - - 0.00000000000000000000000005179 124.0
PYH3_k127_2586300_3 chaperone-mediated protein folding - - - 0.0000000000000000000000006813 121.0
PYH3_k127_2586300_5 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000004967 81.0
PYH3_k127_259173_0 elongation factor Tu domain 2 protein K02355 - - 4.887e-241 764.0
PYH3_k127_259173_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000003205 263.0
PYH3_k127_259173_2 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000283 138.0
PYH3_k127_259173_3 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000001119 128.0
PYH3_k127_259173_4 PFAM response regulator receiver - - - 0.000000000000000000000000008727 114.0
PYH3_k127_259173_5 cyclic nucleotide-binding K10914 - - 0.00000000000000000001758 104.0
PYH3_k127_2603898_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 554.0
PYH3_k127_2603898_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 515.0
PYH3_k127_2603898_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000001629 183.0
PYH3_k127_2603898_3 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000001372 105.0
PYH3_k127_2630349_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 520.0
PYH3_k127_2630349_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 427.0
PYH3_k127_2630349_2 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001577 264.0
PYH3_k127_2630349_3 NfeD-like C-terminal, partner-binding K07340 - - 0.000000000000000000000000000000000000000000000000000001003 195.0
PYH3_k127_2630349_4 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000472 104.0
PYH3_k127_2630349_5 lipolytic protein G-D-S-L family - - - 0.0000000000001404 82.0
PYH3_k127_2630349_6 - - - - 0.00001207 49.0
PYH3_k127_2682895_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 481.0
PYH3_k127_2682895_1 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 418.0
PYH3_k127_2682895_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004676 263.0
PYH3_k127_2682895_4 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000001557 107.0
PYH3_k127_2785662_0 Elongator protein 3, MiaB family, Radical SAM K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 595.0
PYH3_k127_2785662_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 508.0
PYH3_k127_2785662_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000222 281.0
PYH3_k127_2785662_11 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005948 266.0
PYH3_k127_2785662_12 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002245 251.0
PYH3_k127_2785662_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000008672 190.0
PYH3_k127_2785662_14 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000000000000000001912 193.0
PYH3_k127_2785662_15 protein kinase activity K06915 - - 0.0000000000000000000000000000000000004451 143.0
PYH3_k127_2785662_16 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000004991 130.0
PYH3_k127_2785662_17 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.0000000000000000000000000002312 125.0
PYH3_k127_2785662_18 Domain of unknown function DUF11 - - - 0.00000000000000000000006826 118.0
PYH3_k127_2785662_19 C-terminal domain of CHU protein family - - - 0.00000000000001491 90.0
PYH3_k127_2785662_2 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 521.0
PYH3_k127_2785662_21 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.000000000002734 83.0
PYH3_k127_2785662_22 AAA-like domain - - - 0.00000000001683 72.0
PYH3_k127_2785662_24 signal peptide processing K13280 - 3.4.21.89 0.000001536 58.0
PYH3_k127_2785662_25 AAA-like domain - - - 0.00002604 56.0
PYH3_k127_2785662_3 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 440.0
PYH3_k127_2785662_4 sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 421.0
PYH3_k127_2785662_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 419.0
PYH3_k127_2785662_6 Sulfate ABC transporter, permease protein CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
PYH3_k127_2785662_7 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 328.0
PYH3_k127_2785662_8 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 318.0
PYH3_k127_2785662_9 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
PYH3_k127_2794871_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.397e-262 824.0
PYH3_k127_2794871_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 352.0
PYH3_k127_2794871_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 340.0
PYH3_k127_2794871_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000008845 195.0
PYH3_k127_2794871_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000001042 174.0
PYH3_k127_2794871_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006093 134.0
PYH3_k127_2861262_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 7.325e-283 897.0
PYH3_k127_2861262_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 529.0
PYH3_k127_2861262_10 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 324.0
PYH3_k127_2861262_11 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 304.0
PYH3_k127_2861262_12 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000002443 263.0
PYH3_k127_2861262_13 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006378 267.0
PYH3_k127_2861262_14 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000002631 236.0
PYH3_k127_2861262_15 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
PYH3_k127_2861262_16 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000001315 233.0
PYH3_k127_2861262_17 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
PYH3_k127_2861262_18 ABC-2 type transporter K09688,K09690 - - 0.000000000000000000000000000000000000000000000000000000001544 209.0
PYH3_k127_2861262_19 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000000000004483 147.0
PYH3_k127_2861262_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 450.0
PYH3_k127_2861262_20 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K02169 - 2.1.1.197,2.1.1.222,2.1.1.64 0.00000006874 60.0
PYH3_k127_2861262_21 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000007886 62.0
PYH3_k127_2861262_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 434.0
PYH3_k127_2861262_4 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 425.0
PYH3_k127_2861262_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 416.0
PYH3_k127_2861262_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 403.0
PYH3_k127_2861262_7 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 400.0
PYH3_k127_2861262_8 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 382.0
PYH3_k127_2861262_9 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 382.0
PYH3_k127_2865027_0 glutamine synthetase, type I K01915 - 6.3.1.2 1.399e-208 659.0
PYH3_k127_2865027_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 339.0
PYH3_k127_2865027_10 Domain of unknown function (DUF4349) - - - 0.000007005 59.0
PYH3_k127_2865027_11 Domain of unknown function (DUF4340) - - - 0.00006038 55.0
PYH3_k127_2865027_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
PYH3_k127_2865027_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001261 222.0
PYH3_k127_2865027_4 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000002231 231.0
PYH3_k127_2865027_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001157 232.0
PYH3_k127_2865027_6 ECF sigma factor K03088 - - 0.000000000000000000000000000000000001346 148.0
PYH3_k127_2865027_7 metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000008466 137.0
PYH3_k127_2865027_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000001148 134.0
PYH3_k127_2865027_9 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000001539 119.0
PYH3_k127_2914773_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1093.0
PYH3_k127_2914773_1 heme binding K21471 - - 0.000000000000000000000000002764 111.0
PYH3_k127_2914773_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000004554 109.0
PYH3_k127_2914773_3 Tetratricopeptide repeat - - - 0.000000000000008243 90.0
PYH3_k127_2984766_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 380.0
PYH3_k127_2984766_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
PYH3_k127_2984766_10 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000000001138 154.0
PYH3_k127_2984766_11 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000003871 141.0
PYH3_k127_2984766_12 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000001932 136.0
PYH3_k127_2984766_13 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000005997 129.0
PYH3_k127_2984766_14 Tetratricopeptide repeat - - - 0.00000000000000000000000002606 112.0
PYH3_k127_2984766_15 PFAM response regulator receiver - - - 0.0000000000000000000001015 102.0
PYH3_k127_2984766_16 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000007687 108.0
PYH3_k127_2984766_17 lysyltransferase activity K07027 - - 0.0000000000000000001461 104.0
PYH3_k127_2984766_18 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000001022 98.0
PYH3_k127_2984766_19 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.00000000000000006287 94.0
PYH3_k127_2984766_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000004964 192.0
PYH3_k127_2984766_20 - - - - 0.00000004358 66.0
PYH3_k127_2984766_21 PA14 domain - - - 0.000009667 55.0
PYH3_k127_2984766_3 Bacterial transferase hexapeptide (six repeats) K00633,K00661 - 2.3.1.18,2.3.1.79 0.000000000000000000000000000000000000000000000000000228 195.0
PYH3_k127_2984766_4 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000004729 194.0
PYH3_k127_2984766_5 O-methyltransferase, family 2 - - - 0.0000000000000000000000000000000000000000000000001287 192.0
PYH3_k127_2984766_6 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.000000000000000000000000000000000000000000000002126 180.0
PYH3_k127_2984766_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000001086 175.0
PYH3_k127_2984766_8 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000002069 179.0
PYH3_k127_2984766_9 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000007277 180.0
PYH3_k127_3037956_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 489.0
PYH3_k127_3037956_1 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 483.0
PYH3_k127_3037956_10 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000001403 136.0
PYH3_k127_3037956_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000555 124.0
PYH3_k127_3037956_12 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000002459 112.0
PYH3_k127_3037956_13 - - - - 0.000000005486 64.0
PYH3_k127_3037956_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
PYH3_k127_3037956_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 389.0
PYH3_k127_3037956_4 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 342.0
PYH3_k127_3037956_5 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003947 242.0
PYH3_k127_3037956_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000593 230.0
PYH3_k127_3037956_7 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000002114 212.0
PYH3_k127_3037956_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000002273 194.0
PYH3_k127_3037956_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000146 177.0
PYH3_k127_3183286_0 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 378.0
PYH3_k127_3183286_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 375.0
PYH3_k127_3183286_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 295.0
PYH3_k127_3183286_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000000000000000000000000000000000000008475 179.0
PYH3_k127_3183286_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000004214 149.0
PYH3_k127_3312138_0 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 528.0
PYH3_k127_3312138_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 520.0
PYH3_k127_3312138_10 response regulator K02485,K03413 - - 0.00000000000000006364 84.0
PYH3_k127_3312138_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000001283 72.0
PYH3_k127_3312138_12 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000008497 70.0
PYH3_k127_3312138_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 467.0
PYH3_k127_3312138_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
PYH3_k127_3312138_4 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 336.0
PYH3_k127_3312138_5 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
PYH3_k127_3312138_6 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000002435 150.0
PYH3_k127_3312138_7 - - - - 0.000000000000000000000000005271 128.0
PYH3_k127_3312138_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000001072 119.0
PYH3_k127_3312138_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000001189 95.0
PYH3_k127_3330913_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 520.0
PYH3_k127_3330913_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 432.0
PYH3_k127_3330913_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 372.0
PYH3_k127_3330913_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 310.0
PYH3_k127_3330913_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 310.0
PYH3_k127_3330913_5 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
PYH3_k127_3330913_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
PYH3_k127_3330913_7 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000001567 188.0
PYH3_k127_3340223_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 403.0
PYH3_k127_3340223_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 393.0
PYH3_k127_3340223_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 384.0
PYH3_k127_3340223_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 334.0
PYH3_k127_3340223_4 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000009176 82.0
PYH3_k127_3340691_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.104e-206 659.0
PYH3_k127_3340691_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 470.0
PYH3_k127_3340691_2 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000006198 171.0
PYH3_k127_3340691_3 Universal stress protein family - - - 0.0000000000000000000000000000000000000001793 155.0
PYH3_k127_3340691_4 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000001213 125.0
PYH3_k127_3340691_5 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000006561 111.0
PYH3_k127_3340691_6 response regulator, receiver K03407 - 2.7.13.3 0.000000000000000000006699 97.0
PYH3_k127_3340691_7 Protein of unknown function (DUF1573) - - - 0.0000000001585 72.0
PYH3_k127_3340691_8 - - - - 0.0000008043 55.0
PYH3_k127_3439540_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 604.0
PYH3_k127_3439540_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 588.0
PYH3_k127_3439540_10 heat shock protein binding - - - 0.000000000007603 71.0
PYH3_k127_3439540_11 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000003193 53.0
PYH3_k127_3439540_12 hsp70-Hsp90 organizing protein K09553 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009611,GO:0009628,GO:0009987,GO:0010033,GO:0016043,GO:0022607,GO:0031072,GO:0033554,GO:0034605,GO:0034622,GO:0035966,GO:0042221,GO:0043933,GO:0044085,GO:0050896,GO:0051131,GO:0051716,GO:0051879,GO:0065003,GO:0070417,GO:0070678,GO:0071840 - 0.0007801 47.0
PYH3_k127_3439540_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 563.0
PYH3_k127_3439540_3 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 335.0
PYH3_k127_3439540_4 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 291.0
PYH3_k127_3439540_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000006341 234.0
PYH3_k127_3439540_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000002756 148.0
PYH3_k127_3439540_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000002866 151.0
PYH3_k127_3439540_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000002278 108.0
PYH3_k127_3439540_9 denitrification pathway - - - 0.00000000000000000006373 99.0
PYH3_k127_3504621_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.09e-218 693.0
PYH3_k127_3504621_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.195e-209 659.0
PYH3_k127_3504621_10 PFAM ATP synthase subunit C K02124 - - 0.00000000000004112 78.0
PYH3_k127_3504621_11 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000001617 61.0
PYH3_k127_3504621_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000002898 66.0
PYH3_k127_3504621_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0004566 43.0
PYH3_k127_3504621_2 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 379.0
PYH3_k127_3504621_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000007298 223.0
PYH3_k127_3504621_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000002474 199.0
PYH3_k127_3504621_5 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000006767 184.0
PYH3_k127_3504621_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000007175 173.0
PYH3_k127_3504621_7 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000005529 159.0
PYH3_k127_3504621_8 Phospholipid methyltransferase - - - 0.00000000000000000000000000000004364 133.0
PYH3_k127_3504621_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000003838 78.0
PYH3_k127_3548025_0 Domain of unknown function (DUF1998) K06877 - - 1.128e-226 725.0
PYH3_k127_3548025_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 582.0
PYH3_k127_3548025_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 291.0
PYH3_k127_3548025_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006052 247.0
PYH3_k127_3548025_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000004078 172.0
PYH3_k127_3548025_5 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000005421 175.0
PYH3_k127_3548025_6 Extracellular repeat protein, HAF family - - - 0.000000000000000000000000000000000000000004571 168.0
PYH3_k127_3548025_7 system, mannose fructose sorbose family, IID component K02796 - - 0.0000000000000000000002446 110.0
PYH3_k127_3548025_8 Phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000519 93.0
PYH3_k127_35891_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.456e-229 717.0
PYH3_k127_35891_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000002202 244.0
PYH3_k127_35891_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000005669 117.0
PYH3_k127_35891_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000001031 118.0
PYH3_k127_35891_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000002583 115.0
PYH3_k127_35891_5 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000002817 79.0
PYH3_k127_35891_6 ATP synthesis coupled proton transport K02109 - - 0.0000008717 57.0
PYH3_k127_3599230_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1101.0
PYH3_k127_3599230_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.423e-308 965.0
PYH3_k127_3599230_10 Domain of unknown function (DUF4833) - - - 0.000000000000000000000005958 109.0
PYH3_k127_3599230_11 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000006455 108.0
PYH3_k127_3599230_12 Histidine kinase - - - 0.00000000000000002536 90.0
PYH3_k127_3599230_13 TPR repeat - - - 0.000000000000003183 85.0
PYH3_k127_3599230_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 491.0
PYH3_k127_3599230_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 357.0
PYH3_k127_3599230_4 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 332.0
PYH3_k127_3599230_5 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000003135 232.0
PYH3_k127_3599230_6 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000001667 222.0
PYH3_k127_3599230_7 acetyltransferase K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000007607 205.0
PYH3_k127_3599230_8 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000005338 145.0
PYH3_k127_3599230_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000001937 132.0
PYH3_k127_3669898_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 6.729e-210 679.0
PYH3_k127_3669898_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 581.0
PYH3_k127_3669898_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 314.0
PYH3_k127_3669898_11 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 304.0
PYH3_k127_3669898_12 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 292.0
PYH3_k127_3669898_13 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003389 295.0
PYH3_k127_3669898_14 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000005933 213.0
PYH3_k127_3669898_15 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000002599 181.0
PYH3_k127_3669898_16 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000009552 182.0
PYH3_k127_3669898_17 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000001934 189.0
PYH3_k127_3669898_18 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000826 184.0
PYH3_k127_3669898_19 OsmC-like protein K07397 - - 0.00000000000000000000000000000000001862 140.0
PYH3_k127_3669898_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 577.0
PYH3_k127_3669898_20 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000007527 137.0
PYH3_k127_3669898_21 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000003436 147.0
PYH3_k127_3669898_22 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000002399 126.0
PYH3_k127_3669898_23 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000008487 108.0
PYH3_k127_3669898_24 AsnC family - - - 0.0000000000000000118 84.0
PYH3_k127_3669898_25 Tetratricopeptide repeat - - - 0.0000000000003006 81.0
PYH3_k127_3669898_26 Protein of unknown function (DUF3179) - - - 0.000000000006502 73.0
PYH3_k127_3669898_27 Glutathione peroxidase - - - 0.00000843 57.0
PYH3_k127_3669898_28 Tetratricopeptide repeat - - - 0.00002516 57.0
PYH3_k127_3669898_29 - - - - 0.0000958 51.0
PYH3_k127_3669898_3 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 509.0
PYH3_k127_3669898_30 FecR protein - - - 0.00009991 55.0
PYH3_k127_3669898_31 Sulfotransferase family - - - 0.0002117 54.0
PYH3_k127_3669898_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 451.0
PYH3_k127_3669898_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 406.0
PYH3_k127_3669898_6 PFAM peptidase M29, aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 382.0
PYH3_k127_3669898_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 382.0
PYH3_k127_3669898_8 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 352.0
PYH3_k127_3669898_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 350.0
PYH3_k127_367885_0 biotin carboxylase activity K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 586.0
PYH3_k127_367885_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 404.0
PYH3_k127_367885_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 297.0
PYH3_k127_367885_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000003129 180.0
PYH3_k127_367885_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000009479 182.0
PYH3_k127_367885_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000001866 156.0
PYH3_k127_367885_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000008143 156.0
PYH3_k127_367885_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000008948 145.0
PYH3_k127_367885_8 Roadblock/LC7 domain - - - 0.0000001311 58.0
PYH3_k127_367885_9 Tetratricopeptide repeat - - - 0.0000007264 58.0
PYH3_k127_3744066_0 FecR protein - - - 0.0 1088.0
PYH3_k127_3744066_1 CHASE2 K01768 - 4.6.1.1 6.538e-201 649.0
PYH3_k127_3744066_10 COG3209 Rhs family protein - - - 0.000000008938 68.0
PYH3_k127_3744066_11 denitrification pathway - - - 0.000003687 59.0
PYH3_k127_3744066_2 metalloenzyme domain protein K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 458.0
PYH3_k127_3744066_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
PYH3_k127_3744066_4 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000001768 211.0
PYH3_k127_3744066_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000009125 185.0
PYH3_k127_3744066_6 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000726 164.0
PYH3_k127_3744066_7 - - - - 0.00000000000001837 82.0
PYH3_k127_3744066_8 - - - - 0.000000000000359 71.0
PYH3_k127_3744066_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000002519 71.0
PYH3_k127_3747804_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.96e-196 642.0
PYH3_k127_3747804_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 545.0
PYH3_k127_3747804_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 482.0
PYH3_k127_3747804_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 392.0
PYH3_k127_3747804_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
PYH3_k127_3747804_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002046 229.0
PYH3_k127_3747804_6 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.00000000000000000000000000005721 126.0
PYH3_k127_3747804_7 Belongs to the Smg family K03747 - - 0.00000000009463 70.0
PYH3_k127_378967_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 5.965e-199 627.0
PYH3_k127_378967_1 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 506.0
PYH3_k127_378967_10 efflux transmembrane transporter activity K03296,K12340 - - 0.0000000000000000000000000002439 130.0
PYH3_k127_378967_11 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000001938 59.0
PYH3_k127_378967_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 505.0
PYH3_k127_378967_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 444.0
PYH3_k127_378967_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 422.0
PYH3_k127_378967_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 391.0
PYH3_k127_378967_6 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 308.0
PYH3_k127_378967_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000001243 225.0
PYH3_k127_378967_8 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000002093 211.0
PYH3_k127_378967_9 PFAM Radical SAM - - - 0.0000000000000000000000000000000000005701 153.0
PYH3_k127_3800580_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1075.0
PYH3_k127_3800580_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.072e-274 856.0
PYH3_k127_3800580_10 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 350.0
PYH3_k127_3800580_11 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 326.0
PYH3_k127_3800580_12 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 298.0
PYH3_k127_3800580_13 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
PYH3_k127_3800580_14 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000653 274.0
PYH3_k127_3800580_15 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005487 259.0
PYH3_k127_3800580_16 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000005464 263.0
PYH3_k127_3800580_17 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000003039 238.0
PYH3_k127_3800580_18 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000002268 233.0
PYH3_k127_3800580_19 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000002095 230.0
PYH3_k127_3800580_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 582.0
PYH3_k127_3800580_20 RNA-DNA hybrid ribonuclease activity K03470,K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000004223 235.0
PYH3_k127_3800580_21 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000001484 210.0
PYH3_k127_3800580_22 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000003294 214.0
PYH3_k127_3800580_23 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000001527 217.0
PYH3_k127_3800580_24 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000001448 201.0
PYH3_k127_3800580_25 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000004207 200.0
PYH3_k127_3800580_26 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000005558 189.0
PYH3_k127_3800580_27 MgtC family K07507 - - 0.00000000000000000000000000000000000001924 152.0
PYH3_k127_3800580_28 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000223 153.0
PYH3_k127_3800580_29 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000000006008 128.0
PYH3_k127_3800580_3 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 564.0
PYH3_k127_3800580_30 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000002792 87.0
PYH3_k127_3800580_31 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000003541 84.0
PYH3_k127_3800580_32 - - - - 0.0000000000000001687 88.0
PYH3_k127_3800580_33 - - - - 0.0000000000000008458 90.0
PYH3_k127_3800580_34 PFAM YbbR family protein - - - 0.000000000000002027 87.0
PYH3_k127_3800580_35 - - - - 0.00000000000001833 75.0
PYH3_k127_3800580_36 peptidyl-tyrosine sulfation - - - 0.0000000003651 68.0
PYH3_k127_3800580_37 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000006049 68.0
PYH3_k127_3800580_39 Iron-sulfur cluster-binding domain K22227 - - 0.0000001384 63.0
PYH3_k127_3800580_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 435.0
PYH3_k127_3800580_40 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0008703 43.0
PYH3_k127_3800580_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 430.0
PYH3_k127_3800580_6 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 430.0
PYH3_k127_3800580_7 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 394.0
PYH3_k127_3800580_8 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 371.0
PYH3_k127_3800580_9 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 366.0
PYH3_k127_3815141_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.686e-298 939.0
PYH3_k127_3815141_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 495.0
PYH3_k127_3815141_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 436.0
PYH3_k127_3815141_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002698 290.0
PYH3_k127_3815141_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002749 274.0
PYH3_k127_3815141_5 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000006168 195.0
PYH3_k127_3815141_6 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.0000000000000000005895 94.0
PYH3_k127_3815141_7 - - - - 0.0003054 47.0
PYH3_k127_3823327_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 438.0
PYH3_k127_3823327_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 333.0
PYH3_k127_3823327_2 protein secretion K02460 - - 0.000000000000000000000000000000000000007297 158.0
PYH3_k127_3823327_3 Prokaryotic N-terminal methylation motif K02459 - - 0.000000395 61.0
PYH3_k127_3823327_4 Pilus assembly protein K02461,K02662 - - 0.00003266 55.0
PYH3_k127_3823327_5 general secretion pathway protein K02458 - - 0.0003791 49.0
PYH3_k127_3864585_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 9.373e-195 633.0
PYH3_k127_3864585_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 560.0
PYH3_k127_3864585_2 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 479.0
PYH3_k127_3864585_3 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 467.0
PYH3_k127_3864585_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 462.0
PYH3_k127_3864585_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
PYH3_k127_3864585_6 Domain of unknown function DUF128 K09720 - - 0.00000000000000000000000000000000000005979 147.0
PYH3_k127_3864585_7 Type II secretion system protein B K02451 - - 0.00000000364 68.0
PYH3_k127_3864585_8 Histidine kinase K07646 - 2.7.13.3 0.000000012 60.0
PYH3_k127_3886093_0 Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 488.0
PYH3_k127_3886093_1 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 467.0
PYH3_k127_3886093_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001431 269.0
PYH3_k127_3886093_11 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000009933 259.0
PYH3_k127_3886093_12 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000003058 168.0
PYH3_k127_3886093_13 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000008043 160.0
PYH3_k127_3886093_14 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000001454 150.0
PYH3_k127_3886093_15 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000005913 155.0
PYH3_k127_3886093_16 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000002661 139.0
PYH3_k127_3886093_17 Evidence 5 No homology to any previously reported sequences - - - 0.0000008507 59.0
PYH3_k127_3886093_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 449.0
PYH3_k127_3886093_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 389.0
PYH3_k127_3886093_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
PYH3_k127_3886093_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 319.0
PYH3_k127_3886093_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 318.0
PYH3_k127_3886093_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 322.0
PYH3_k127_3886093_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 289.0
PYH3_k127_3886093_9 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 280.0
PYH3_k127_4007953_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 519.0
PYH3_k127_4007953_1 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 415.0
PYH3_k127_4007953_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000241 274.0
PYH3_k127_4007953_3 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000218 219.0
PYH3_k127_4007953_4 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000008504 221.0
PYH3_k127_4007953_5 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000005981 212.0
PYH3_k127_4007953_6 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000007296 181.0
PYH3_k127_4007953_7 phosphorelay signal transduction system - - - 0.0000000001739 69.0
PYH3_k127_4058586_0 Domain of unknown function (DUF1846) - - - 1.342e-264 822.0
PYH3_k127_4058586_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 475.0
PYH3_k127_4058586_2 PFAM Basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 410.0
PYH3_k127_4058586_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 368.0
PYH3_k127_4058586_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 366.0
PYH3_k127_4058586_5 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000003314 98.0
PYH3_k127_4058586_6 SMART Tetratricopeptide domain protein - - - 0.00000000000000001946 89.0
PYH3_k127_4058586_7 cellulase activity K20276 - - 0.0000000000002777 83.0
PYH3_k127_4077772_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1689.0
PYH3_k127_4077772_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 604.0
PYH3_k127_4077772_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000009584 129.0
PYH3_k127_4077772_11 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000001419 113.0
PYH3_k127_4077772_12 TIGRFAM diguanylate cyclase - - - 0.0000000000000000000002188 108.0
PYH3_k127_4077772_13 Thioredoxin - - - 0.0000000000000000000008259 100.0
PYH3_k127_4077772_14 HD domain K07814 - - 0.0000000000000001149 91.0
PYH3_k127_4077772_15 - - - - 0.000000000000003003 78.0
PYH3_k127_4077772_16 - - - - 0.000000002875 59.0
PYH3_k127_4077772_2 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 496.0
PYH3_k127_4077772_3 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 412.0
PYH3_k127_4077772_4 PFAM homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000204 289.0
PYH3_k127_4077772_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000343 263.0
PYH3_k127_4077772_6 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000002347 246.0
PYH3_k127_4077772_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000003532 175.0
PYH3_k127_4077772_8 Thioredoxin - - - 0.00000000000000000000000000000000000000000006735 164.0
PYH3_k127_4077772_9 PFAM nitroreductase - - - 0.00000000000000000000000000000003748 132.0
PYH3_k127_4078847_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 362.0
PYH3_k127_4078847_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 347.0
PYH3_k127_4078847_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001703 280.0
PYH3_k127_4078847_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
PYH3_k127_4078847_4 Putative glutamine amidotransferase K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000364 265.0
PYH3_k127_4078847_5 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000001527 158.0
PYH3_k127_4078847_6 4 iron, 4 sulfur cluster binding - - - 0.00000000001989 65.0
PYH3_k127_4078847_7 Transmembrane and TPR repeat-containing protein 1 - - - 0.000003258 58.0
PYH3_k127_4078847_8 Aerotolerance regulator N-terminal - - - 0.000007891 59.0
PYH3_k127_4108706_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.442e-266 829.0
PYH3_k127_4108706_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 493.0
PYH3_k127_4108706_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
PYH3_k127_4108706_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 445.0
PYH3_k127_4108706_4 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001104 290.0
PYH3_k127_4108706_5 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
PYH3_k127_4108706_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002998 282.0
PYH3_k127_4108706_7 NIL - - - 0.0000000000000000000000000000000000000000001313 163.0
PYH3_k127_4108706_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001203 153.0
PYH3_k127_4108706_9 addiction module antidote protein HigA K21498 - - 0.000000000000000000000000000000009879 129.0
PYH3_k127_4179665_0 DEAD DEAH box helicase K06877 - - 2.651e-291 925.0
PYH3_k127_4179665_1 FtsX-like permease family K02004 - - 2.749e-274 867.0
PYH3_k127_4179665_10 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000001896 207.0
PYH3_k127_4179665_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000335 194.0
PYH3_k127_4179665_12 - - - - 0.000000000000000000000000000000000000000000000000193 180.0
PYH3_k127_4179665_13 DinB superfamily - - - 0.000000000000000000000000000000000000000000002426 170.0
PYH3_k127_4179665_14 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000006435 175.0
PYH3_k127_4179665_15 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000004201 165.0
PYH3_k127_4179665_16 Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000002701 131.0
PYH3_k127_4179665_17 metallopeptidase activity - - - 0.00000000000000000000000000001046 130.0
PYH3_k127_4179665_18 - - - - 0.00000000000000000000000005109 110.0
PYH3_k127_4179665_19 Rhodanese Homology Domain - - - 0.00000000000000000000000007831 114.0
PYH3_k127_4179665_2 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 543.0
PYH3_k127_4179665_20 mRNA binding K07339 - - 0.0000000000000000000002054 98.0
PYH3_k127_4179665_21 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000003287 98.0
PYH3_k127_4179665_22 sulfur carrier activity - - - 0.000000000001434 78.0
PYH3_k127_4179665_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000000007782 74.0
PYH3_k127_4179665_3 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 486.0
PYH3_k127_4179665_4 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 347.0
PYH3_k127_4179665_5 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 321.0
PYH3_k127_4179665_6 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
PYH3_k127_4179665_7 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001096 250.0
PYH3_k127_4179665_8 PFAM GCN5-related N-acetyltransferase K03824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000198 237.0
PYH3_k127_4179665_9 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000001582 227.0
PYH3_k127_4220741_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 575.0
PYH3_k127_4220741_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 475.0
PYH3_k127_4220741_10 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000006378 172.0
PYH3_k127_4220741_11 - - - - 0.00000000000000000000000000000000000000002067 166.0
PYH3_k127_4220741_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000006121 171.0
PYH3_k127_4220741_13 PQQ-like domain - - - 0.0000000000000000000000000000000000004601 155.0
PYH3_k127_4220741_14 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.00000000000000000000000000000348 129.0
PYH3_k127_4220741_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 289.0
PYH3_k127_4220741_3 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009589 255.0
PYH3_k127_4220741_4 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000018 232.0
PYH3_k127_4220741_5 domain protein - - - 0.000000000000000000000000000000000000000000000000001321 198.0
PYH3_k127_4220741_6 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000001244 189.0
PYH3_k127_4220741_7 - - - - 0.0000000000000000000000000000000000000000000000009747 188.0
PYH3_k127_4220741_8 - - - - 0.00000000000000000000000000000000000000000000005947 187.0
PYH3_k127_4220741_9 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000269 178.0
PYH3_k127_4234403_0 SMART Elongator protein 3 MiaB NifB K22227 - - 4.643e-207 647.0
PYH3_k127_4234403_1 HI0933-like protein K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 439.0
PYH3_k127_4234403_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
PYH3_k127_4234403_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 366.0
PYH3_k127_4234403_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
PYH3_k127_4234403_5 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.00000000000000000000000002361 111.0
PYH3_k127_4234403_6 self proteolysis K01081,K01119,K01286,K01992,K07258 - 3.1.3.5,3.1.3.6,3.1.4.16,3.4.16.4 0.0000000001103 74.0
PYH3_k127_4234403_7 type IV pilus modification protein PilV K02458,K02671 - - 0.00000001459 64.0
PYH3_k127_4234403_8 Type II transport protein GspH K08084 - - 0.00005061 52.0
PYH3_k127_4234403_9 Type IV Pilus-assembly protein W K02672 - - 0.0001718 54.0
PYH3_k127_4237711_0 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 541.0
PYH3_k127_4237711_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 477.0
PYH3_k127_4237711_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
PYH3_k127_4237711_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003187 252.0
PYH3_k127_4237711_4 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000001793 136.0
PYH3_k127_4237711_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000001164 117.0
PYH3_k127_4331003_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000005135 198.0
PYH3_k127_4331003_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000009114 155.0
PYH3_k127_4331003_2 Class III cytochrome C family - - - 0.0003158 49.0
PYH3_k127_4337152_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 502.0
PYH3_k127_4337152_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 473.0
PYH3_k127_4337152_10 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005158 270.0
PYH3_k127_4337152_11 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
PYH3_k127_4337152_12 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001503 244.0
PYH3_k127_4337152_13 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004289 221.0
PYH3_k127_4337152_14 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000001894 204.0
PYH3_k127_4337152_15 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000161 220.0
PYH3_k127_4337152_16 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000002675 190.0
PYH3_k127_4337152_17 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000000000000000000000000000000002581 175.0
PYH3_k127_4337152_18 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000005307 168.0
PYH3_k127_4337152_19 SMART Cold shock protein K03704 - - 0.00000000000000000000000008708 108.0
PYH3_k127_4337152_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 471.0
PYH3_k127_4337152_20 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000007281 101.0
PYH3_k127_4337152_21 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000004153 81.0
PYH3_k127_4337152_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 451.0
PYH3_k127_4337152_4 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 403.0
PYH3_k127_4337152_5 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 333.0
PYH3_k127_4337152_6 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 347.0
PYH3_k127_4337152_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 324.0
PYH3_k127_4337152_8 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 310.0
PYH3_k127_4337152_9 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004197 286.0
PYH3_k127_4399771_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 521.0
PYH3_k127_4399771_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000001421 103.0
PYH3_k127_4448489_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1099.0
PYH3_k127_4448489_1 Seven times multi-haem cytochrome CxxCH - - - 3.244e-205 649.0
PYH3_k127_4448489_10 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000397 209.0
PYH3_k127_4448489_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000468 197.0
PYH3_k127_4448489_12 Transglycosylase K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000004755 194.0
PYH3_k127_4448489_13 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000002984 188.0
PYH3_k127_4448489_14 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000000000000000000003192 182.0
PYH3_k127_4448489_15 - - - - 0.00000000000000000000000000000000000006687 145.0
PYH3_k127_4448489_16 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000133 113.0
PYH3_k127_4448489_17 - - - - 0.00000000000139 76.0
PYH3_k127_4448489_2 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 611.0
PYH3_k127_4448489_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 419.0
PYH3_k127_4448489_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 411.0
PYH3_k127_4448489_5 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 356.0
PYH3_k127_4448489_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
PYH3_k127_4448489_8 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002 297.0
PYH3_k127_4448489_9 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000001431 231.0
PYH3_k127_4543302_0 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 373.0
PYH3_k127_4543302_1 Restriction endonuclease - - - 0.00000000000000000000000000000000000004929 143.0
PYH3_k127_4543302_2 - - - - 0.0000000000000000000000000000007927 125.0
PYH3_k127_4543302_3 ORF6N domain - - - 0.00000000000000000000000000004652 119.0
PYH3_k127_4543302_4 - - - - 0.000000000000000000002044 98.0
PYH3_k127_4543302_5 ORF6N domain - - - 0.000000000007652 66.0
PYH3_k127_4543302_6 Bacterial extracellular solute-binding protein K10938 - - 0.00007137 51.0
PYH3_k127_4578728_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.92e-274 861.0
PYH3_k127_4578728_1 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000000000000000000000000000913 246.0
PYH3_k127_4578728_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000006566 233.0
PYH3_k127_4578728_3 Histidine kinase K07651 - 2.7.13.3 0.00000000000000000000000000000000000000000000000005004 200.0
PYH3_k127_4578728_4 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000002475 134.0
PYH3_k127_4578728_5 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000009727 130.0
PYH3_k127_4578728_6 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000001891 114.0
PYH3_k127_4578728_7 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000003766 78.0
PYH3_k127_4578728_8 Domain of unknown function (DUF1858) - - - 0.00000000001305 69.0
PYH3_k127_462673_0 ABC transporter K06020 - 3.6.3.25 2.256e-281 876.0
PYH3_k127_462673_1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 2.352e-231 730.0
PYH3_k127_462673_10 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000007248 239.0
PYH3_k127_462673_11 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002647 207.0
PYH3_k127_462673_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001774 186.0
PYH3_k127_462673_13 Universal stress protein - - - 0.000000000000000000000000000000000000000000000001073 184.0
PYH3_k127_462673_14 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000005343 176.0
PYH3_k127_462673_15 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000105 187.0
PYH3_k127_462673_16 Curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000003253 175.0
PYH3_k127_462673_17 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000001801 175.0
PYH3_k127_462673_18 Protein of unknown function (DUF975) - - - 0.0000000000000000000000000000000000000009563 158.0
PYH3_k127_462673_19 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000001129 143.0
PYH3_k127_462673_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 423.0
PYH3_k127_462673_20 Acyltransferase family - - - 0.0000000000000000000000000000000006486 144.0
PYH3_k127_462673_21 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000001237 143.0
PYH3_k127_462673_22 Flavodoxin-like fold - - - 0.00000000000000000000000000001264 132.0
PYH3_k127_462673_23 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000000008979 121.0
PYH3_k127_462673_24 NifU-like domain - - - 0.000000000000000000000000003707 113.0
PYH3_k127_462673_25 NHL repeat - - - 0.000000000000000000000001119 123.0
PYH3_k127_462673_26 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000003009 99.0
PYH3_k127_462673_27 oligosaccharyl transferase activity - - - 0.00000000000000000001168 107.0
PYH3_k127_462673_28 - - - - 0.0000000000000000247 93.0
PYH3_k127_462673_29 Rubrerythrin - - - 0.0000000000000008479 84.0
PYH3_k127_462673_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 377.0
PYH3_k127_462673_30 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000002905 70.0
PYH3_k127_462673_31 PA14 domain - - - 0.0000000001068 76.0
PYH3_k127_462673_33 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00003313 52.0
PYH3_k127_462673_34 type IV pilus assembly PilZ - - - 0.0006148 46.0
PYH3_k127_462673_4 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 346.0
PYH3_k127_462673_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 335.0
PYH3_k127_462673_6 ThiS-like ubiquitin K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 299.0
PYH3_k127_462673_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 289.0
PYH3_k127_462673_8 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
PYH3_k127_462673_9 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000105 259.0
PYH3_k127_4662060_0 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 372.0
PYH3_k127_4662060_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 302.0
PYH3_k127_4662060_2 ABC transporter K01996,K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008619 257.0
PYH3_k127_4662060_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009659 274.0
PYH3_k127_4896502_0 Amp-dependent synthetase and ligase K00655,K01897 - 2.3.1.51,6.2.1.3 8.543e-255 816.0
PYH3_k127_4896502_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000157 265.0
PYH3_k127_4896502_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000004528 255.0
PYH3_k127_4896502_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000008579 186.0
PYH3_k127_5022564_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000005763 211.0
PYH3_k127_5022564_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000001053 181.0
PYH3_k127_5022564_2 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000003703 125.0
PYH3_k127_5022564_3 Bacterial membrane protein YfhO - - - 0.0000000000006172 81.0
PYH3_k127_5059731_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 314.0
PYH3_k127_5059731_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 294.0
PYH3_k127_5059731_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 288.0
PYH3_k127_5059731_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000001088 271.0
PYH3_k127_5059731_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000007877 184.0
PYH3_k127_5059731_5 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000001249 189.0
PYH3_k127_5059731_6 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000002772 185.0
PYH3_k127_5059731_7 Glycosyl transferases group 1 K02844 - - 0.00000000000000000000000000000000000000004761 165.0
PYH3_k127_5059731_8 - - - - 0.00003554 49.0
PYH3_k127_5071658_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 602.0
PYH3_k127_5071658_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 530.0
PYH3_k127_5071658_10 - - - - 0.0000002285 57.0
PYH3_k127_5071658_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0005965 51.0
PYH3_k127_5071658_2 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 491.0
PYH3_k127_5071658_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
PYH3_k127_5071658_4 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 297.0
PYH3_k127_5071658_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000005355 263.0
PYH3_k127_5071658_6 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000005558 233.0
PYH3_k127_5071658_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000004109 212.0
PYH3_k127_5071658_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.00000000000000000000000000000000000000001454 166.0
PYH3_k127_5071658_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000002206 71.0
PYH3_k127_5139692_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 591.0
PYH3_k127_5139692_1 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 396.0
PYH3_k127_5139692_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009488 357.0
PYH3_k127_5139692_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
PYH3_k127_5139692_4 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001182 234.0
PYH3_k127_5193471_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 466.0
PYH3_k127_5193471_1 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 405.0
PYH3_k127_5193471_2 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 367.0
PYH3_k127_5193471_3 Glycosyl transferase family 41 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.00000000000002078 80.0
PYH3_k127_5224210_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.124e-272 867.0
PYH3_k127_5224210_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 2.544e-246 779.0
PYH3_k127_5224210_10 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.00000000000000000000000000000000000002498 161.0
PYH3_k127_5224210_11 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000000000000000005979 147.0
PYH3_k127_5224210_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000004086 107.0
PYH3_k127_5224210_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000002135 81.0
PYH3_k127_5224210_14 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000002278 82.0
PYH3_k127_5224210_15 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.00000000001041 77.0
PYH3_k127_5224210_16 COG0500 SAM-dependent methyltransferases K03183 - 2.1.1.163,2.1.1.201 0.0000000001485 74.0
PYH3_k127_5224210_17 NHL repeat - - - 0.0001612 53.0
PYH3_k127_5224210_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 416.0
PYH3_k127_5224210_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 395.0
PYH3_k127_5224210_4 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
PYH3_k127_5224210_5 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 296.0
PYH3_k127_5224210_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000009862 192.0
PYH3_k127_5224210_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000009533 194.0
PYH3_k127_5224210_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000001362 183.0
PYH3_k127_5224210_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000571 154.0
PYH3_k127_5225098_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004393 276.0
PYH3_k127_5225098_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000001915 200.0
PYH3_k127_5225098_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000002433 192.0
PYH3_k127_5225098_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000004961 152.0
PYH3_k127_5225098_4 Chemotaxis protein CheY K02658 - - 0.00000000000000000000000002657 115.0
PYH3_k127_5225098_5 SpoVG K06412 - - 0.0000000000000001148 83.0
PYH3_k127_5225098_6 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000007836 68.0
PYH3_k127_5233130_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 576.0
PYH3_k127_5233130_1 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 490.0
PYH3_k127_5233130_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000001395 190.0
PYH3_k127_5233130_11 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000003798 193.0
PYH3_k127_5233130_12 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH3_k127_5233130_13 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000002553 164.0
PYH3_k127_5233130_14 Belongs to the V-ATPase proteolipid subunit family K02124 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000002091 143.0
PYH3_k127_5233130_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000001858 141.0
PYH3_k127_5233130_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000001005 123.0
PYH3_k127_5233130_17 metal-dependent phosphohydrolase HD region - - - 0.000000005477 67.0
PYH3_k127_5233130_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 477.0
PYH3_k127_5233130_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 370.0
PYH3_k127_5233130_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 316.0
PYH3_k127_5233130_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 327.0
PYH3_k127_5233130_6 116 kDa subunit K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 314.0
PYH3_k127_5233130_7 YceG-like family K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001059 268.0
PYH3_k127_5233130_8 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000007697 222.0
PYH3_k127_5233130_9 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000888 227.0
PYH3_k127_5234350_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 514.0
PYH3_k127_5234350_1 PFAM Type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008294 258.0
PYH3_k127_5234350_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000007922 172.0
PYH3_k127_5234350_3 nucleotide catabolic process - - - 0.0000000000000003085 93.0
PYH3_k127_5234350_4 Receptor family ligand binding region K01999 - - 0.00001112 54.0
PYH3_k127_5290448_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 456.0
PYH3_k127_5290448_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 406.0
PYH3_k127_5290448_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 392.0
PYH3_k127_5290448_3 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 368.0
PYH3_k127_5290448_4 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 364.0
PYH3_k127_5290448_5 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000006415 199.0
PYH3_k127_5290448_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000001745 125.0
PYH3_k127_5290448_7 Domain of unknown function (DUF362) - - - 0.00000000000000000002927 98.0
PYH3_k127_5326536_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 428.0
PYH3_k127_5326536_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003313 268.0
PYH3_k127_5326536_2 aconitate hydratase K01681 - 4.2.1.3 0.000000000000000000000000000000000003713 140.0
PYH3_k127_5326536_3 - - - - 0.0000000000000000000008993 100.0
PYH3_k127_5367333_0 hydrogenase large subunit K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 456.0
PYH3_k127_5367333_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 378.0
PYH3_k127_5367333_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001147 267.0
PYH3_k127_5367333_3 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000005569 122.0
PYH3_k127_5367333_4 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.000000000000000000000000133 106.0
PYH3_k127_5367333_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000284 74.0
PYH3_k127_5370331_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 7.884e-268 839.0
PYH3_k127_5370331_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.455e-226 723.0
PYH3_k127_5370331_10 Ribosomal protein L35 K02916 - - 0.00000000000000000000005004 100.0
PYH3_k127_5370331_11 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000006651 96.0
PYH3_k127_5370331_12 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000002544 92.0
PYH3_k127_5370331_13 Protein of unknown function (DUF448) K07742 - - 0.0000000000000001364 88.0
PYH3_k127_5370331_14 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.0000000000002119 72.0
PYH3_k127_5370331_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000001677 66.0
PYH3_k127_5370331_16 Cell division protein ZapA K09888 - - 0.00000000004264 67.0
PYH3_k127_5370331_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 594.0
PYH3_k127_5370331_3 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 438.0
PYH3_k127_5370331_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 369.0
PYH3_k127_5370331_5 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 313.0
PYH3_k127_5370331_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
PYH3_k127_5370331_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000001646 149.0
PYH3_k127_5370331_8 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000007753 138.0
PYH3_k127_5370331_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000001871 109.0
PYH3_k127_539880_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 558.0
PYH3_k127_539880_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 441.0
PYH3_k127_539880_2 Wzt C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 328.0
PYH3_k127_539880_3 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 325.0
PYH3_k127_539880_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 293.0
PYH3_k127_539880_5 O-Antigen ligase - - - 0.0000000000000000000000000000000001717 149.0
PYH3_k127_539880_6 Transcriptional regulator - - - 0.0000000000000000000000006002 109.0
PYH3_k127_5485009_0 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000468 276.0
PYH3_k127_5485009_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007732 254.0
PYH3_k127_5485009_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007839 245.0
PYH3_k127_5485009_3 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000002826 233.0
PYH3_k127_5485009_4 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000002598 211.0
PYH3_k127_5485009_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000003821 187.0
PYH3_k127_5485009_6 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000003298 162.0
PYH3_k127_5485009_7 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000002287 154.0
PYH3_k127_5485009_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000201 145.0
PYH3_k127_5485009_9 Sh3 type 3 domain protein K02450,K12132 - 2.7.11.1 0.000000000000001083 85.0
PYH3_k127_5485677_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000002625 210.0
PYH3_k127_5485677_2 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000005151 60.0
PYH3_k127_5515604_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000001956 142.0
PYH3_k127_5515604_1 Bacterial membrane protein YfhO - - - 0.0006588 51.0
PYH3_k127_5543641_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001822 265.0
PYH3_k127_5543641_1 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 260.0
PYH3_k127_5543641_2 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000007832 190.0
PYH3_k127_5543641_3 nuclease activity K18828 - - 0.0000000000000000000000000000000000001197 145.0
PYH3_k127_5543641_4 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000004029 94.0
PYH3_k127_5543641_5 - - - - 0.00000002883 59.0
PYH3_k127_5545102_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 499.0
PYH3_k127_5545102_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000004889 265.0
PYH3_k127_5545102_2 amine dehydrogenase activity K20276,K21430 - - 0.00003015 56.0
PYH3_k127_5589150_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003054 281.0
PYH3_k127_5589150_1 - - - - 0.00000000000000000000000000000000000000000000000000000000006455 220.0
PYH3_k127_5589150_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000001014 126.0
PYH3_k127_5589150_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000001882 102.0
PYH3_k127_5611183_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 383.0
PYH3_k127_5611183_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 330.0
PYH3_k127_5611183_2 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003424 310.0
PYH3_k127_5611183_3 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000002337 232.0
PYH3_k127_5611183_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000001567 157.0
PYH3_k127_5611183_5 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000002235 113.0
PYH3_k127_5611183_6 RHS Repeat - - - 0.0000000000000000001295 106.0
PYH3_k127_5611183_7 TIGRFAM YD repeat protein - - - 0.000000005482 71.0
PYH3_k127_56320_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 8.079e-209 661.0
PYH3_k127_56320_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 488.0
PYH3_k127_56320_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 468.0
PYH3_k127_56320_3 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000000000000000000000005427 175.0
PYH3_k127_56320_4 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000001806 161.0
PYH3_k127_5653170_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 398.0
PYH3_k127_5653170_1 Efflux ABC transporter permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 358.0
PYH3_k127_5653170_2 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 353.0
PYH3_k127_5653170_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006571 262.0
PYH3_k127_5653170_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
PYH3_k127_5653170_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000001693 196.0
PYH3_k127_5653170_6 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000005104 125.0
PYH3_k127_5653170_7 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000001394 126.0
PYH3_k127_5653170_8 Protein of unknown function (DUF2905) - - - 0.00000000001408 70.0
PYH3_k127_5729545_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 352.0
PYH3_k127_5729545_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006472 271.0
PYH3_k127_5729545_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002745 269.0
PYH3_k127_5729545_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000001695 237.0
PYH3_k127_5729545_4 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000001356 204.0
PYH3_k127_5729545_5 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000002474 184.0
PYH3_k127_5729545_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000003661 77.0
PYH3_k127_5729545_7 histidine kinase HAMP region domain protein - - - 0.000000002302 60.0
PYH3_k127_5758115_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 400.0
PYH3_k127_5758115_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 381.0
PYH3_k127_5758115_10 cellulase activity - - - 0.00000000003388 76.0
PYH3_k127_5758115_11 - - - - 0.0000000007173 67.0
PYH3_k127_5758115_12 Arginase family K01480 - 3.5.3.11 0.0000001066 62.0
PYH3_k127_5758115_13 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component' - GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.00004577 51.0
PYH3_k127_5758115_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 348.0
PYH3_k127_5758115_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 311.0
PYH3_k127_5758115_4 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 300.0
PYH3_k127_5758115_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 299.0
PYH3_k127_5758115_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000182 284.0
PYH3_k127_5758115_7 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004663 257.0
PYH3_k127_5758115_8 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000009932 178.0
PYH3_k127_5758115_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000003901 163.0
PYH3_k127_5820210_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 459.0
PYH3_k127_5820210_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001384 304.0
PYH3_k127_5820210_2 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002175 259.0
PYH3_k127_5820210_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000001431 130.0
PYH3_k127_5820210_4 Glycosyltransferase family 9 (heptosyltransferase) K02841 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000004247 126.0
PYH3_k127_5820210_5 copG family - - - 0.00000000000000000007866 91.0
PYH3_k127_5820210_6 Belongs to the 'phage' integrase family - - - 0.00002902 53.0
PYH3_k127_5838713_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1268.0
PYH3_k127_5838713_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.277e-240 759.0
PYH3_k127_5838713_10 subunit c K02119 - - 0.0000000000000000004078 99.0
PYH3_k127_5838713_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000001773 64.0
PYH3_k127_5838713_12 general secretion pathway protein K02457,K02650 - - 0.0000002132 59.0
PYH3_k127_5838713_13 Putative regulatory protein - - - 0.000004084 56.0
PYH3_k127_5838713_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.177e-215 678.0
PYH3_k127_5838713_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 376.0
PYH3_k127_5838713_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 372.0
PYH3_k127_5838713_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
PYH3_k127_5838713_6 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000002568 180.0
PYH3_k127_5838713_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000002364 163.0
PYH3_k127_5838713_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000001165 129.0
PYH3_k127_5838713_9 - - - - 0.000000000000000000000000006795 124.0
PYH3_k127_5841538_0 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 386.0
PYH3_k127_5841538_1 PFAM Beta-ketoacyl synthase K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001236 293.0
PYH3_k127_5841538_2 PFAM Lipid A 3-O-deacylase-related - - - 0.000000000000000000000000000000000000000000000002755 179.0
PYH3_k127_5841538_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000004351 175.0
PYH3_k127_5841538_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000009653 82.0
PYH3_k127_5850781_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1392.0
PYH3_k127_5850781_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.081e-211 675.0
PYH3_k127_5850781_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 310.0
PYH3_k127_5850781_11 anaerobic respiration - - - 0.00000000000000000000000000000000000000000000000000000000000000263 237.0
PYH3_k127_5850781_12 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000004241 183.0
PYH3_k127_5850781_13 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000002111 130.0
PYH3_k127_5850781_14 Bacterial regulatory protein, Fis family - - - 0.000000000000000009088 94.0
PYH3_k127_5850781_15 Tetratricopeptide repeat - - - 0.0000000000000425 86.0
PYH3_k127_5850781_16 TIGRFAM addiction module toxin, RelE StbE family K06218 - - 0.00000000004947 66.0
PYH3_k127_5850781_17 ferrous iron transmembrane transporter activity - - - 0.00000001402 57.0
PYH3_k127_5850781_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 524.0
PYH3_k127_5850781_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 486.0
PYH3_k127_5850781_4 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 406.0
PYH3_k127_5850781_5 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
PYH3_k127_5850781_6 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 355.0
PYH3_k127_5850781_7 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
PYH3_k127_5850781_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 352.0
PYH3_k127_5850781_9 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 308.0
PYH3_k127_6039601_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.519e-246 781.0
PYH3_k127_6039601_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 404.0
PYH3_k127_6039601_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001016 285.0
PYH3_k127_6039601_3 HEAT repeats - - - 0.0000000000000000000000000000000000000000000004994 187.0
PYH3_k127_6039601_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000008459 160.0
PYH3_k127_6039601_5 response regulator K07720 - - 0.000000000000000000001608 104.0
PYH3_k127_6091286_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 344.0
PYH3_k127_6091286_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000001532 210.0
PYH3_k127_6091286_2 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000001119 201.0
PYH3_k127_6091286_3 - - - - 0.0000000000000000000000000000000005973 149.0
PYH3_k127_6150170_0 Carbamoyltransferase C-terminus K00612 - - 5.926e-273 850.0
PYH3_k127_6150170_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 407.0
PYH3_k127_6150170_10 - - - - 0.000000000000001603 87.0
PYH3_k127_6150170_11 - - - - 0.000000000000002162 77.0
PYH3_k127_6150170_12 Acyltransferase family - - - 0.00000000004853 74.0
PYH3_k127_6150170_2 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 342.0
PYH3_k127_6150170_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
PYH3_k127_6150170_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
PYH3_k127_6150170_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001268 288.0
PYH3_k127_6150170_6 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000009149 248.0
PYH3_k127_6150170_7 acetyltransferase, isoleucine patch superfamily K03818 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
PYH3_k127_6150170_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000002645 139.0
PYH3_k127_6150170_9 - - - - 0.00000000000000001088 88.0
PYH3_k127_6151414_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.77e-241 760.0
PYH3_k127_6151414_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 422.0
PYH3_k127_6151414_10 domain protein K03499 - - 0.00002032 48.0
PYH3_k127_6151414_2 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 386.0
PYH3_k127_6151414_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
PYH3_k127_6151414_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002808 269.0
PYH3_k127_6151414_5 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000001043 266.0
PYH3_k127_6151414_6 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000001277 197.0
PYH3_k127_6151414_7 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000001193 196.0
PYH3_k127_6151414_8 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000393 180.0
PYH3_k127_6151414_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000004033 79.0
PYH3_k127_6169761_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000003201 131.0
PYH3_k127_6169761_1 Bacterial membrane protein YfhO - - - 0.0000000000367 76.0
PYH3_k127_6267295_0 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
PYH3_k127_6267295_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 263.0
PYH3_k127_6267295_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000002817 242.0
PYH3_k127_6267295_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000001887 197.0
PYH3_k127_6267295_4 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000001536 148.0
PYH3_k127_6267295_5 Domain of unknown function (DUF4115) - - - 0.0000000000000000000009477 106.0
PYH3_k127_6267295_6 cheY-homologous receiver domain - - - 0.000000000000000000002244 103.0
PYH3_k127_6267295_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0005304 52.0
PYH3_k127_6381966_0 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000004432 198.0
PYH3_k127_6381966_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000164 159.0
PYH3_k127_6381966_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000003027 103.0
PYH3_k127_6381966_3 4Fe-4S binding domain - - - 0.000000000000000562 82.0
PYH3_k127_6381966_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000003851 67.0
PYH3_k127_6381966_5 - - - - 0.000000000005587 79.0
PYH3_k127_6393660_0 P-type ATPase K17686 - 3.6.3.54 1.384e-235 758.0
PYH3_k127_6393660_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 469.0
PYH3_k127_6393660_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 409.0
PYH3_k127_6393660_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
PYH3_k127_6393660_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000007887 207.0
PYH3_k127_6393660_5 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000000000133 172.0
PYH3_k127_6393660_6 - - - - 0.0000005911 59.0
PYH3_k127_643488_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005968 243.0
PYH3_k127_643488_1 oligosaccharyl transferase activity - - - 0.0000000000000000007523 98.0
PYH3_k127_643488_2 lipolytic protein G-D-S-L family K20306 - - 0.00000001977 66.0
PYH3_k127_6478960_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 507.0
PYH3_k127_6478960_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 424.0
PYH3_k127_6478960_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 328.0
PYH3_k127_6478960_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 322.0
PYH3_k127_6557640_0 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 557.0
PYH3_k127_6557640_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 400.0
PYH3_k127_6557640_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000008736 197.0
PYH3_k127_6557640_3 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.0000000000000000000000000000000000000000000000000002732 203.0
PYH3_k127_6557640_4 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000001163 193.0
PYH3_k127_6598454_0 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 462.0
PYH3_k127_6598454_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 448.0
PYH3_k127_6598454_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 431.0
PYH3_k127_6598454_3 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000365 219.0
PYH3_k127_6598454_4 - - - - 0.0000000000000008131 87.0
PYH3_k127_6598454_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000003104 64.0
PYH3_k127_6598454_6 small metal-binding protein - - - 0.0000003612 54.0
PYH3_k127_6678355_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 589.0
PYH3_k127_6678355_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 559.0
PYH3_k127_6678355_10 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 306.0
PYH3_k127_6678355_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000002914 213.0
PYH3_k127_6678355_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000001681 115.0
PYH3_k127_6678355_13 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000248 107.0
PYH3_k127_6678355_14 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000002078 80.0
PYH3_k127_6678355_15 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000002322 74.0
PYH3_k127_6678355_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 535.0
PYH3_k127_6678355_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 494.0
PYH3_k127_6678355_4 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 427.0
PYH3_k127_6678355_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 401.0
PYH3_k127_6678355_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 388.0
PYH3_k127_6678355_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 387.0
PYH3_k127_6678355_8 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 307.0
PYH3_k127_6678355_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 295.0
PYH3_k127_6865924_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 586.0
PYH3_k127_6865924_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 559.0
PYH3_k127_6865924_10 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002023 275.0
PYH3_k127_6865924_12 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000007986 248.0
PYH3_k127_6865924_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001136 251.0
PYH3_k127_6865924_14 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000001799 234.0
PYH3_k127_6865924_15 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001349 182.0
PYH3_k127_6865924_16 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000005471 168.0
PYH3_k127_6865924_17 1,7-bisphosphate phosphatase - - - 0.000000000000000000000000000000000000000831 155.0
PYH3_k127_6865924_18 Peptidase family M48 - - - 0.00000000000000000000000000000000000125 152.0
PYH3_k127_6865924_19 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000192 141.0
PYH3_k127_6865924_2 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 478.0
PYH3_k127_6865924_20 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP - - - 0.000000000000000000000000000006043 127.0
PYH3_k127_6865924_21 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000001033 93.0
PYH3_k127_6865924_22 ubiE/COQ5 methyltransferase family - - - 0.0000000000001001 82.0
PYH3_k127_6865924_23 SH3 domain - - - 0.00000006681 64.0
PYH3_k127_6865924_24 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000002031 61.0
PYH3_k127_6865924_25 COG3209 Rhs family protein - - - 0.0002269 53.0
PYH3_k127_6865924_26 PFAM UbiA prenyltransferase - - - 0.0003703 43.0
PYH3_k127_6865924_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 400.0
PYH3_k127_6865924_4 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 380.0
PYH3_k127_6865924_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 384.0
PYH3_k127_6865924_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 344.0
PYH3_k127_6865924_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 296.0
PYH3_k127_6865924_8 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003532 270.0
PYH3_k127_6865924_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002198 291.0
PYH3_k127_6910735_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
PYH3_k127_6910735_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 402.0
PYH3_k127_6910735_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 366.0
PYH3_k127_6910735_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000001469 235.0
PYH3_k127_6910735_4 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000004476 218.0
PYH3_k127_7037532_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 611.0
PYH3_k127_7037532_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 556.0
PYH3_k127_7037532_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 501.0
PYH3_k127_7037532_3 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 441.0
PYH3_k127_7037532_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 332.0
PYH3_k127_7037532_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003238 273.0
PYH3_k127_7037532_6 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000001177 201.0
PYH3_k127_7037532_7 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000001316 208.0
PYH3_k127_7037532_8 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000002184 196.0
PYH3_k127_7037532_9 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000002075 159.0
PYH3_k127_705889_0 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000007027 197.0
PYH3_k127_705889_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000007844 167.0
PYH3_k127_705889_2 anaerobic respiration - - - 0.000000000000000000000000000202 118.0
PYH3_k127_705889_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000002574 116.0
PYH3_k127_705889_5 denitrification pathway - - - 0.000000000000001433 88.0
PYH3_k127_705889_8 ExbD TolR K03559 - - 0.00000001712 61.0
PYH3_k127_7275486_0 SMART Elongator protein 3 MiaB NifB - - - 5.31e-224 723.0
PYH3_k127_7275486_1 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 558.0
PYH3_k127_7275486_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000164 126.0
PYH3_k127_7275486_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000001731 120.0
PYH3_k127_7275486_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 513.0
PYH3_k127_7275486_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 411.0
PYH3_k127_7275486_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 382.0
PYH3_k127_7275486_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 293.0
PYH3_k127_7275486_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000003432 232.0
PYH3_k127_7275486_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000001225 193.0
PYH3_k127_7275486_8 - K16923 - - 0.000000000000000000000000000000000000000000000003547 199.0
PYH3_k127_7275486_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000003216 191.0
PYH3_k127_7287643_0 PFAM cation transporter K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 515.0
PYH3_k127_7287643_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008069 276.0
PYH3_k127_7287643_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000002241 167.0
PYH3_k127_7287643_3 - - - - 0.000000000000000000000006338 117.0
PYH3_k127_7287643_4 Tetratricopeptide repeat - - - 0.0000000000000002295 87.0
PYH3_k127_7319412_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1038.0
PYH3_k127_7319412_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0000000000000000000000000000000000000000000000000000313 196.0
PYH3_k127_7319412_2 protein trimerization K02453 - - 0.000000001142 65.0
PYH3_k127_7351527_0 Cache domain - - - 7.185e-258 808.0
PYH3_k127_7351527_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 488.0
PYH3_k127_7351527_10 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000001164 237.0
PYH3_k127_7351527_11 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000504 241.0
PYH3_k127_7351527_12 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000005793 227.0
PYH3_k127_7351527_13 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.0000000000000000000000000000000000000000000000000000000000001609 221.0
PYH3_k127_7351527_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000008675 207.0
PYH3_k127_7351527_15 inorganic diphosphatase activity K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000009496 203.0
PYH3_k127_7351527_16 Membrane - - - 0.00000000000000000000000000000000000000000000000000001964 191.0
PYH3_k127_7351527_17 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000001094 196.0
PYH3_k127_7351527_18 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000009332 186.0
PYH3_k127_7351527_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000006707 160.0
PYH3_k127_7351527_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 453.0
PYH3_k127_7351527_21 Cupin domain - - - 0.0000000000000000000000000000001047 126.0
PYH3_k127_7351527_22 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000001172 126.0
PYH3_k127_7351527_23 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000003663 81.0
PYH3_k127_7351527_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 442.0
PYH3_k127_7351527_4 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 394.0
PYH3_k127_7351527_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 375.0
PYH3_k127_7351527_6 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 348.0
PYH3_k127_7351527_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 323.0
PYH3_k127_7351527_8 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001843 279.0
PYH3_k127_7351527_9 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006506 248.0
PYH3_k127_7390376_0 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 404.0
PYH3_k127_7390376_1 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001701 218.0
PYH3_k127_7390376_10 endonuclease activity - - - 0.000000000000007283 79.0
PYH3_k127_7390376_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0004167 53.0
PYH3_k127_7390376_2 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000002425 166.0
PYH3_k127_7390376_3 phenylacetic acid degradation protein PaaD K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.00000000000000000000000000000009479 131.0
PYH3_k127_7390376_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000001192 127.0
PYH3_k127_7390376_5 - - - - 0.000000000000000000000000000002112 125.0
PYH3_k127_7390376_6 mRNA binding - - - 0.0000000000000000000000000008982 116.0
PYH3_k127_7390376_7 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000000011 111.0
PYH3_k127_7390376_8 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000586 113.0
PYH3_k127_7390376_9 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000004375 96.0
PYH3_k127_7398579_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 396.0
PYH3_k127_7398579_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 293.0
PYH3_k127_7398579_10 - - - - 0.00005475 52.0
PYH3_k127_7398579_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
PYH3_k127_7398579_3 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000006643 223.0
PYH3_k127_7398579_4 Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000665 198.0
PYH3_k127_7398579_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000004253 166.0
PYH3_k127_7398579_6 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000005123 167.0
PYH3_k127_7398579_7 - - - - 0.0000000000000000000000000000000000001557 159.0
PYH3_k127_7398579_8 PFAM glutaredoxin - - - 0.0000000000000000000006205 98.0
PYH3_k127_7398579_9 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000007379 89.0
PYH3_k127_7417830_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.236e-214 672.0
PYH3_k127_7417830_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 351.0
PYH3_k127_7417830_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000005612 232.0
PYH3_k127_7417830_3 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000002132 195.0
PYH3_k127_7417830_4 Transposase DDE domain - - - 0.00000000002794 63.0
PYH3_k127_7417830_5 chlorophyll binding - - - 0.0000003049 65.0
PYH3_k127_7456424_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 2.46e-210 683.0
PYH3_k127_7456424_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 2.066e-198 629.0
PYH3_k127_7456424_2 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 531.0
PYH3_k127_7456424_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 433.0
PYH3_k127_7456424_4 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 289.0
PYH3_k127_7456424_5 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000001047 176.0
PYH3_k127_7456424_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000001151 145.0
PYH3_k127_7456424_7 Phosphoglucose isomerase - - - 0.00000000000000000000000000000007629 127.0
PYH3_k127_7456424_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000001898 93.0
PYH3_k127_7461182_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 368.0
PYH3_k127_7461182_1 Peptidase family M23 K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000001022 263.0
PYH3_k127_7461182_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000001529 211.0
PYH3_k127_7461182_3 PFAM FMN-binding domain - - - 0.0000000000000000000000000000000000000000000002457 184.0
PYH3_k127_7461182_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000001249 169.0
PYH3_k127_7461182_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000004165 138.0
PYH3_k127_7461182_6 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.000008925 59.0
PYH3_k127_7492381_0 CheA signal transduction histidine K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 402.0
PYH3_k127_7492381_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002151 293.0
PYH3_k127_7492381_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000003954 198.0
PYH3_k127_7492381_3 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000002079 169.0
PYH3_k127_7492381_4 Phospholipase K07001 - - 0.0000000000000001337 91.0
PYH3_k127_7492381_5 chemotaxis signal transduction protein K03408 - - 0.00000002235 66.0
PYH3_k127_7492381_6 Redoxin - - - 0.0003381 48.0
PYH3_k127_7509952_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 434.0
PYH3_k127_7509952_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 342.0
PYH3_k127_7509952_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007004 252.0
PYH3_k127_7509952_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000007547 148.0
PYH3_k127_7509952_4 transferase, hexapeptide repeat - - - 0.0000000000000000000000000000000001308 136.0
PYH3_k127_7509952_5 - - - - 0.0000000006523 62.0
PYH3_k127_7519100_0 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 364.0
PYH3_k127_7519100_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000003339 186.0
PYH3_k127_7519100_2 nucleoside recognition domain protein - - - 0.0000000000000000000000000000005136 130.0
PYH3_k127_7519100_3 Nucleoside recognition - - - 0.00000000000000000004658 100.0
PYH3_k127_7519100_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000001 70.0
PYH3_k127_754591_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.584e-229 728.0
PYH3_k127_754591_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 581.0
PYH3_k127_754591_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 431.0
PYH3_k127_754591_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 398.0
PYH3_k127_754591_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000001045 254.0
PYH3_k127_754591_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000164 247.0
PYH3_k127_754591_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000009476 204.0
PYH3_k127_754591_7 denitrification pathway - - - 0.00000000000000000000000000000000000000000000006326 188.0
PYH3_k127_754591_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002203 165.0
PYH3_k127_754591_9 Histone deacetylase domain K04768 - - 0.0000000000000000000002154 102.0
PYH3_k127_7566806_0 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000001822 262.0
PYH3_k127_7566806_1 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000008152 237.0
PYH3_k127_7566806_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000007772 117.0
PYH3_k127_7566806_3 Protein of unknown function DUF86 - - - 0.00000000000000000000000001799 112.0
PYH3_k127_7566806_4 PIN domain - - - 0.00000000000000000000000002484 114.0
PYH3_k127_7566806_5 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000001896 100.0
PYH3_k127_7566806_6 SpoVT / AbrB like domain - - - 0.00000000003415 66.0
PYH3_k127_7566806_7 Pentapeptide repeats (9 copies) K15352,K18555 - - 0.000000001614 70.0
PYH3_k127_7566806_8 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000001494 56.0
PYH3_k127_7566806_9 AMP-binding enzyme K01912 - 6.2.1.30 0.00006446 47.0
PYH3_k127_7612834_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 421.0
PYH3_k127_7612834_1 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000001223 187.0
PYH3_k127_7612834_2 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000004175 179.0
PYH3_k127_7612834_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000004071 165.0
PYH3_k127_7612834_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000001483 114.0
PYH3_k127_7612834_5 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000143 58.0
PYH3_k127_7642510_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 448.0
PYH3_k127_7642510_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 374.0
PYH3_k127_7642510_10 enoyl-CoA hydratase K01715 - 4.2.1.17 0.000000000000000000000000000001717 130.0
PYH3_k127_7642510_11 NAD+ binding K00022 - 1.1.1.35 0.000000000000000000002305 108.0
PYH3_k127_7642510_12 acyl carrier protein K02078 - - 0.0000000000000001076 84.0
PYH3_k127_7642510_13 Domain of unknown function (DUF4872) - - - 0.00000000001151 67.0
PYH3_k127_7642510_14 Fibronectin type III domain protein K21571 - - 0.00005061 52.0
PYH3_k127_7642510_15 - - - - 0.0002762 52.0
PYH3_k127_7642510_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 330.0
PYH3_k127_7642510_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 299.0
PYH3_k127_7642510_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002842 292.0
PYH3_k127_7642510_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000749 290.0
PYH3_k127_7642510_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
PYH3_k127_7642510_7 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000003882 169.0
PYH3_k127_7642510_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000007516 136.0
PYH3_k127_7642510_9 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000001434 136.0
PYH3_k127_7696397_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1172.0
PYH3_k127_7696397_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 9.603e-227 749.0
PYH3_k127_7696397_10 TIGRFAM YD repeat protein - - - 0.000006165 53.0
PYH3_k127_7696397_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 548.0
PYH3_k127_7696397_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 522.0
PYH3_k127_7696397_4 malonyl-CoA biosynthetic process K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 377.0
PYH3_k127_7696397_5 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 299.0
PYH3_k127_7696397_6 arylsulfatase activity K07014 - - 0.000000000000000000000000000000000000000000000000000000134 218.0
PYH3_k127_7696397_7 LysE type translocator - - - 0.000000000000000000000000000000000000000000000002515 181.0
PYH3_k127_7696397_8 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000003544 113.0
PYH3_k127_7696397_9 - - - - 0.00000000000000000000005164 109.0
PYH3_k127_7729191_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 523.0
PYH3_k127_7729191_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 442.0
PYH3_k127_7729191_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
PYH3_k127_7729191_3 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 394.0
PYH3_k127_7729191_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 285.0
PYH3_k127_7729191_5 anaerobic respiration - - - 0.00000000000000000000000000000000000000000000000000005368 209.0
PYH3_k127_7729191_6 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000002008 168.0
PYH3_k127_7729191_7 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000001201 125.0
PYH3_k127_7729191_8 SMART Tetratricopeptide - - - 0.000000000000000000002857 101.0
PYH3_k127_77357_0 MMPL family K07003 - - 4.194e-211 681.0
PYH3_k127_77357_1 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 499.0
PYH3_k127_77357_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 430.0
PYH3_k127_77357_3 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 397.0
PYH3_k127_77357_4 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000005917 212.0
PYH3_k127_77357_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000002307 201.0
PYH3_k127_77357_6 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000008449 163.0
PYH3_k127_77357_7 dehydratase - - - 0.000000000000000000000000000000001468 138.0
PYH3_k127_77357_8 - - - - 0.0000000000000000000000000005889 121.0
PYH3_k127_77357_9 PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ K02372 - 4.2.1.59 0.0000000000000000003557 92.0
PYH3_k127_7757229_0 Heat shock 70 kDa protein K04043 - - 4.207e-297 922.0
PYH3_k127_7757229_1 Cytochrome c554 and c-prime - - - 2.575e-221 714.0
PYH3_k127_7757229_10 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 317.0
PYH3_k127_7757229_11 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
PYH3_k127_7757229_12 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 308.0
PYH3_k127_7757229_13 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000968 284.0
PYH3_k127_7757229_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001809 271.0
PYH3_k127_7757229_15 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000001335 235.0
PYH3_k127_7757229_16 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000006694 228.0
PYH3_k127_7757229_17 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000000000000000002809 209.0
PYH3_k127_7757229_18 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000002942 193.0
PYH3_k127_7757229_19 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000008834 206.0
PYH3_k127_7757229_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 586.0
PYH3_k127_7757229_20 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000001853 195.0
PYH3_k127_7757229_21 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000008061 182.0
PYH3_k127_7757229_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000591 174.0
PYH3_k127_7757229_23 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000199 164.0
PYH3_k127_7757229_24 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000001724 144.0
PYH3_k127_7757229_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000004626 144.0
PYH3_k127_7757229_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000005298 141.0
PYH3_k127_7757229_27 PFAM CheW domain protein K03408 - - 0.000000000000000000000002894 109.0
PYH3_k127_7757229_28 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000004171 93.0
PYH3_k127_7757229_29 - - - - 0.000000008925 66.0
PYH3_k127_7757229_3 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 488.0
PYH3_k127_7757229_30 - - - - 0.0000001226 63.0
PYH3_k127_7757229_32 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00001737 56.0
PYH3_k127_7757229_33 Putative zinc-finger - - - 0.0005947 49.0
PYH3_k127_7757229_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 466.0
PYH3_k127_7757229_5 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 464.0
PYH3_k127_7757229_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 456.0
PYH3_k127_7757229_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 366.0
PYH3_k127_7757229_8 smart pdz dhr glgf K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 353.0
PYH3_k127_7757229_9 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 339.0
PYH3_k127_7798098_0 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 421.0
PYH3_k127_7798098_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 351.0
PYH3_k127_7798098_10 histidine kinase A domain protein - - - 0.00000000000000000000000000000003447 135.0
PYH3_k127_7798098_11 Kelch motif - - - 0.000000000000000000000001338 112.0
PYH3_k127_7798098_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000001566 106.0
PYH3_k127_7798098_13 Protein of unknown function (DUF3343) - - - 0.000000001465 64.0
PYH3_k127_7798098_14 - - - - 0.00000007408 57.0
PYH3_k127_7798098_15 RDD family - - - 0.0000001321 64.0
PYH3_k127_7798098_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 350.0
PYH3_k127_7798098_3 Transcriptional regulator IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 293.0
PYH3_k127_7798098_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
PYH3_k127_7798098_5 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.00000000000000000000000000000000000000000000000000000000004755 222.0
PYH3_k127_7798098_6 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000005098 207.0
PYH3_k127_7798098_7 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000001584 201.0
PYH3_k127_7798098_8 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000001175 176.0
PYH3_k127_7798098_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000002564 167.0
PYH3_k127_7815651_0 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 338.0
PYH3_k127_7815651_1 PFAM ketose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001491 280.0
PYH3_k127_7815651_2 GAF domain - - - 0.00000000000000000000000000000000000000000001888 171.0
PYH3_k127_7815651_3 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000323 117.0
PYH3_k127_7815651_4 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000001985 110.0
PYH3_k127_7815651_5 lactoylglutathione lyase activity K01759,K05606,K08234 - 4.4.1.5,5.1.99.1 0.0000000005772 69.0
PYH3_k127_7899517_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.393e-217 685.0
PYH3_k127_7899517_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 386.0
PYH3_k127_7899517_10 PAS domain - - - 0.0000000000000000000000000000002612 138.0
PYH3_k127_7899517_11 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000004912 81.0
PYH3_k127_7899517_13 Two component signalling adaptor domain K03408 - - 0.0001728 51.0
PYH3_k127_7899517_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 377.0
PYH3_k127_7899517_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 362.0
PYH3_k127_7899517_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 337.0
PYH3_k127_7899517_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000854 250.0
PYH3_k127_7899517_6 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000003629 211.0
PYH3_k127_7899517_7 response regulator - - - 0.0000000000000000000000000000000000000001678 163.0
PYH3_k127_7899517_8 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000001012 149.0
PYH3_k127_7899517_9 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - 0.000000000000000000000000000000000003754 154.0
PYH3_k127_8078312_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 1.724e-219 699.0
PYH3_k127_8078312_1 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
PYH3_k127_8078312_2 S4 RNA-binding domain - - - 0.00000000000000001251 85.0
PYH3_k127_8078312_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.00000000000005203 79.0
PYH3_k127_8078312_4 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00001371 55.0
PYH3_k127_8182695_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 329.0
PYH3_k127_8182695_1 3' exoribonuclease family, domain 2 K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 319.0
PYH3_k127_8182695_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
PYH3_k127_8182695_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000151 231.0
PYH3_k127_8182695_4 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000006346 203.0
PYH3_k127_8182695_5 Omptin family - - - 0.0000000000000000000000000000000000000005895 162.0
PYH3_k127_8182695_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000001823 112.0
PYH3_k127_8182695_7 Sporulation and spore germination - - - 0.00000000000001841 81.0
PYH3_k127_8220181_0 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 586.0
PYH3_k127_8220181_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000009186 197.0
PYH3_k127_8220181_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000004331 119.0
PYH3_k127_8260787_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 586.0
PYH3_k127_8260787_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 316.0
PYH3_k127_8260787_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 313.0
PYH3_k127_8260787_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007419 247.0
PYH3_k127_8260787_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979,K19714 - 1.1.3.48,2.7.7.38 0.00000000000000000000000000000000000000000000000000000001722 207.0
PYH3_k127_8260787_5 Methyltransferase domain - - - 0.0000000000000000000000005842 115.0
PYH3_k127_8260787_6 O-Antigen ligase K18814 - - 0.0000000000000001345 93.0
PYH3_k127_8260787_7 PFAM Glycosyl transferase family 2 - - - 0.0000001626 53.0
PYH3_k127_8342091_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 401.0
PYH3_k127_8342091_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 395.0
PYH3_k127_8342091_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000006933 148.0
PYH3_k127_8342091_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 0.000000000000000000000000000000000002182 142.0
PYH3_k127_8346764_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 9.808e-206 672.0
PYH3_k127_8346764_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 528.0
PYH3_k127_8346764_2 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 361.0
PYH3_k127_8346764_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 362.0
PYH3_k127_8346764_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 260.0
PYH3_k127_8346764_5 PFAM Rubrerythrin - - - 0.000000000000000000000004221 108.0
PYH3_k127_8346764_6 AAA domain K07133 - - 0.000000000000000683 81.0
PYH3_k127_8346764_7 ResB-like family - - - 0.0000000000001413 82.0
PYH3_k127_8346764_8 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0002558 52.0
PYH3_k127_8351095_0 GTP-binding protein TypA K06207 - - 1.48e-259 813.0
PYH3_k127_8351095_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 1.728e-231 727.0
PYH3_k127_8351095_2 ABC transporter, transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 554.0
PYH3_k127_8351095_3 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 502.0
PYH3_k127_8351095_4 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 432.0
PYH3_k127_8351095_5 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009893 252.0
PYH3_k127_8351095_6 Iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000006065 218.0
PYH3_k127_8351095_7 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000244 204.0
PYH3_k127_8351095_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000001688 100.0
PYH3_k127_8393670_0 General secretory system II, protein E domain protein K02454 - - 1.872e-270 843.0
PYH3_k127_8393670_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 450.0
PYH3_k127_8393670_10 response regulator receiver K02481 - - 0.000000000000000000004336 97.0
PYH3_k127_8393670_11 COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription - - - 0.000000000000000000006699 97.0
PYH3_k127_8393670_12 EamA-like transporter family - - - 0.0000000000000000001889 92.0
PYH3_k127_8393670_13 - - - - 0.000000000000000006146 85.0
PYH3_k127_8393670_15 - - - - 0.000000000000002482 79.0
PYH3_k127_8393670_16 thiol-disulfide isomerase and thioredoxins - - - 0.0000000000001026 79.0
PYH3_k127_8393670_17 Methyltransferase domain - - - 0.000000000006262 77.0
PYH3_k127_8393670_2 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 411.0
PYH3_k127_8393670_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 400.0
PYH3_k127_8393670_4 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 355.0
PYH3_k127_8393670_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000002984 223.0
PYH3_k127_8393670_6 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000005292 204.0
PYH3_k127_8393670_7 DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000002747 170.0
PYH3_k127_8393670_8 Phosphate ABC transporter substrate-binding protein K02040 - - 0.0000000000000000000000000000007691 133.0
PYH3_k127_8393670_9 EamA-like transporter family - - - 0.00000000000000000000000008161 120.0
PYH3_k127_8400228_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 559.0
PYH3_k127_8400228_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 544.0
PYH3_k127_8400228_10 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000001414 179.0
PYH3_k127_8400228_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000003097 119.0
PYH3_k127_8400228_12 Preprotein translocase subunit K03210 - - 0.0000000000000000000002158 100.0
PYH3_k127_8400228_13 Parallel beta-helix repeats - - - 0.0000000000000000000002463 113.0
PYH3_k127_8400228_14 cheY-homologous receiver domain - - - 0.00000000000000001864 87.0
PYH3_k127_8400228_15 Pfam Adenylate and Guanylate cyclase catalytic domain K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000009782 94.0
PYH3_k127_8400228_16 Recombination protein O C terminal K03584 - - 0.00000000000001023 84.0
PYH3_k127_8400228_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 418.0
PYH3_k127_8400228_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 415.0
PYH3_k127_8400228_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 303.0
PYH3_k127_8400228_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001782 263.0
PYH3_k127_8400228_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007167 256.0
PYH3_k127_8400228_7 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000002487 229.0
PYH3_k127_8400228_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000001022 211.0
PYH3_k127_8400228_9 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000006251 190.0
PYH3_k127_8498335_0 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 439.0
PYH3_k127_8498335_1 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
PYH3_k127_8498335_10 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000001199 157.0
PYH3_k127_8498335_11 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000005622 137.0
PYH3_k127_8498335_12 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000001544 127.0
PYH3_k127_8498335_13 NUDIX hydrolase - - - 0.00000000000000001123 91.0
PYH3_k127_8498335_14 lipolytic protein G-D-S-L family - - - 0.00000001216 67.0
PYH3_k127_8498335_15 MORN repeat variant - - - 0.00000002563 63.0
PYH3_k127_8498335_16 Nad-dependent epimerase dehydratase - - - 0.000003062 52.0
PYH3_k127_8498335_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
PYH3_k127_8498335_3 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 367.0
PYH3_k127_8498335_4 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 336.0
PYH3_k127_8498335_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K01784,K12450 - 4.2.1.46,4.2.1.76,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 267.0
PYH3_k127_8498335_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006142 255.0
PYH3_k127_8498335_7 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000003545 223.0
PYH3_k127_8498335_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000001075 158.0
PYH3_k127_8498335_9 Cupin 2, conserved barrel domain protein K01810 - 5.3.1.9 0.00000000000000000000000000000000000002415 149.0
PYH3_k127_852665_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000003653 158.0
PYH3_k127_852665_1 Bacterial membrane protein YfhO - - - 0.000000000004924 79.0
PYH3_k127_8561005_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 508.0
PYH3_k127_8561005_1 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 411.0
PYH3_k127_8561005_2 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 384.0
PYH3_k127_8561005_3 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 375.0
PYH3_k127_8561005_4 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
PYH3_k127_8561005_5 Sensor diguanylate cyclase, PAS domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 314.0
PYH3_k127_8561005_6 Glycosyltransferase, group 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 300.0
PYH3_k127_8561005_7 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000004416 219.0
PYH3_k127_8561005_8 Histidine kinase A domain protein K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000003614 188.0
PYH3_k127_8561005_9 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000004055 181.0
PYH3_k127_8591351_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 583.0
PYH3_k127_8591351_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 306.0
PYH3_k127_8591351_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009113 259.0
PYH3_k127_8591351_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000002484 174.0
PYH3_k127_8591351_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000006718 154.0
PYH3_k127_8591351_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000001031 155.0
PYH3_k127_8591351_6 Transcriptional regulator - - - 0.0000000000000000000265 93.0
PYH3_k127_8591351_9 Helix-turn-helix - - - 0.00009549 48.0
PYH3_k127_8619363_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.263e-295 924.0
PYH3_k127_8619363_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.49e-221 690.0
PYH3_k127_8619363_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 316.0
PYH3_k127_8619363_3 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000006529 230.0
PYH3_k127_8619363_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
PYH3_k127_8619363_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000513 166.0
PYH3_k127_8619363_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000009084 132.0
PYH3_k127_8619363_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000001778 88.0
PYH3_k127_8619363_8 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000006889 81.0
PYH3_k127_8619363_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000009909 60.0
PYH3_k127_8627236_0 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
PYH3_k127_8627236_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000001327 211.0
PYH3_k127_8627236_2 ComF family K02242 - - 0.0000000000000000000000000000000000514 144.0
PYH3_k127_8627236_3 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000134 139.0
PYH3_k127_8627236_4 chain release factor K15034 - - 0.000000000000000000000000002131 116.0
PYH3_k127_8627236_5 HEAT repeat - - - 0.000000000000000006679 89.0
PYH3_k127_8627236_6 Bacterial Ig-like domain (group 3) - - - 0.000000000000004932 89.0
PYH3_k127_8627236_7 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000007819 59.0
PYH3_k127_8645888_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 478.0
PYH3_k127_8645888_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 469.0
PYH3_k127_8645888_2 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 338.0
PYH3_k127_8658086_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1882.0
PYH3_k127_8658086_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1670.0
PYH3_k127_8658086_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000001448 103.0
PYH3_k127_8658086_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000003103 84.0
PYH3_k127_8658086_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002863 61.0
PYH3_k127_8658086_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2e-323 1004.0
PYH3_k127_8658086_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 319.0
PYH3_k127_8658086_4 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000001377 231.0
PYH3_k127_8658086_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
PYH3_k127_8658086_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
PYH3_k127_8658086_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000478 214.0
PYH3_k127_8658086_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000008059 171.0
PYH3_k127_8658086_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002608 133.0
PYH3_k127_8710544_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 503.0
PYH3_k127_8710544_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 503.0
PYH3_k127_8710544_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000005352 132.0
PYH3_k127_8710544_11 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000001383 121.0
PYH3_k127_8710544_12 Belongs to the ompA family K03640 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - 0.00000000000000000006294 94.0
PYH3_k127_8710544_13 regulatory protein RecX K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002956 79.0
PYH3_k127_8710544_14 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000004624 58.0
PYH3_k127_8710544_15 Putative beta-barrel porin 2 K20920 - - 0.000007305 58.0
PYH3_k127_8710544_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 477.0
PYH3_k127_8710544_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
PYH3_k127_8710544_4 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000005848 185.0
PYH3_k127_8710544_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000281 183.0
PYH3_k127_8710544_6 pfam php K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000005685 187.0
PYH3_k127_8710544_7 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000001661 174.0
PYH3_k127_8710544_8 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000001065 152.0
PYH3_k127_8710544_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000003686 156.0
PYH3_k127_8758849_0 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000000000000000007667 206.0
PYH3_k127_8758849_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000612 183.0
PYH3_k127_8758849_2 FecR protein - - - 0.00000000007463 72.0
PYH3_k127_8758849_3 HEPN domain - - - 0.0000005005 59.0
PYH3_k127_8814145_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 609.0
PYH3_k127_8814145_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 496.0
PYH3_k127_8814145_2 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 357.0
PYH3_k127_8814145_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000002288 249.0
PYH3_k127_8814145_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000005293 190.0
PYH3_k127_8814145_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000003121 162.0
PYH3_k127_8814145_6 - - - - 0.000000000000000000000000000005606 139.0
PYH3_k127_8814145_7 ABC transporter substrate binding protein K01989 - - 0.0000000000000002024 92.0
PYH3_k127_8834424_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 556.0
PYH3_k127_8834424_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 283.0
PYH3_k127_8834424_2 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003756 256.0
PYH3_k127_8834424_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000221 212.0
PYH3_k127_8834424_4 PFAM haloacid - - - 0.00000000000000000000000000000000000000001157 162.0
PYH3_k127_8834424_5 - - - - 0.0000000000000000000000000000000000006916 143.0
PYH3_k127_8834424_6 IMG reference gene - - - 0.00000000000000000000000000000001311 145.0
PYH3_k127_8834424_7 - - - - 0.0000004817 59.0
PYH3_k127_8874219_0 Peptidase family M28 - - - 0.0 1028.0
PYH3_k127_8874219_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.456e-223 713.0
PYH3_k127_8874219_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 379.0
PYH3_k127_8874219_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 370.0
PYH3_k127_8874219_4 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 328.0
PYH3_k127_8874219_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 287.0
PYH3_k127_8874219_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0002776 49.0
PYH3_k127_8896534_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 362.0
PYH3_k127_8896534_1 PFAM Extracellular solute-binding protein, family 3 K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 343.0
PYH3_k127_8896534_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 327.0
PYH3_k127_8896534_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 310.0
PYH3_k127_8896534_4 Lysin motif - - - 0.0000000000000000000003286 109.0
PYH3_k127_8896534_5 Outer membrane lipoprotein - - - 0.0000000000000000000003416 106.0
PYH3_k127_8896534_6 Protein of unknown function (DUF721) - - - 0.00000000005406 69.0
PYH3_k127_8945797_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 573.0
PYH3_k127_8945797_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 430.0
PYH3_k127_8945797_10 - - - - 0.000000000000000000000000000000003085 131.0
PYH3_k127_8945797_11 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000758 90.0
PYH3_k127_8945797_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 372.0
PYH3_k127_8945797_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 370.0
PYH3_k127_8945797_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
PYH3_k127_8945797_5 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 257.0
PYH3_k127_8945797_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005933 245.0
PYH3_k127_8945797_7 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000004378 234.0
PYH3_k127_8945797_8 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000111 211.0
PYH3_k127_8945797_9 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000002444 151.0
PYH3_k127_8947268_0 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 419.0
PYH3_k127_8947268_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000007143 244.0
PYH3_k127_8947268_2 transglycosylase K08309 - - 0.0000000000000000000000000000000008985 150.0
PYH3_k127_8960311_0 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000133 281.0
PYH3_k127_8960311_1 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000001175 209.0
PYH3_k127_8960311_2 Histidine kinase K02491 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001782 217.0
PYH3_k127_8960311_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000002344 141.0
PYH3_k127_8960311_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000003283 78.0
PYH3_k127_8960311_5 Diguanylate cyclase - - - 0.00000000000005254 87.0
PYH3_k127_8960311_6 His Kinase A (phosphoacceptor) domain - - - 0.000131 49.0
PYH3_k127_8964415_0 involved in lipopolysaccharide K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 308.0
PYH3_k127_8964415_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005198 235.0
PYH3_k127_8964415_2 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000006288 195.0
PYH3_k127_8964415_3 polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000357 160.0
PYH3_k127_8964415_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000476 140.0
PYH3_k127_8969860_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 3.167e-209 677.0
PYH3_k127_8969860_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 557.0
PYH3_k127_8969860_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 347.0
PYH3_k127_8969860_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 315.0
PYH3_k127_8969860_4 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000005257 174.0
PYH3_k127_8969860_5 PFAM peptidase - - - 0.000000000000000000000000000000009152 138.0
PYH3_k127_8969860_6 'Cold-shock' DNA-binding domain K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000001268 106.0
PYH3_k127_9054726_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 394.0
PYH3_k127_9054726_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002847 298.0
PYH3_k127_9054726_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000001416 106.0
PYH3_k127_9054726_3 Parallel beta-helix repeats - - - 0.00000000000000001315 98.0
PYH3_k127_9054726_4 amine dehydrogenase activity - - - 0.000000000000005801 89.0
PYH3_k127_9056109_0 CBS domain containing protein K00974 - 2.7.7.72 1.032e-221 718.0
PYH3_k127_9056109_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 574.0
PYH3_k127_9056109_10 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004489 273.0
PYH3_k127_9056109_11 Subtilase family K01342 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000008661 274.0
PYH3_k127_9056109_12 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001742 256.0
PYH3_k127_9056109_13 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000007843 229.0
PYH3_k127_9056109_14 membrane organization K20543 - - 0.00000000000000000000000000000000000000000000000000000000000003021 229.0
PYH3_k127_9056109_15 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000007407 214.0
PYH3_k127_9056109_16 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000154 203.0
PYH3_k127_9056109_17 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000002924 193.0
PYH3_k127_9056109_18 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000001633 184.0
PYH3_k127_9056109_19 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000001122 179.0
PYH3_k127_9056109_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 582.0
PYH3_k127_9056109_20 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000134 163.0
PYH3_k127_9056109_21 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000004488 138.0
PYH3_k127_9056109_22 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000938 123.0
PYH3_k127_9056109_23 deoxyhypusine monooxygenase activity - - - 0.000000000000000000005048 109.0
PYH3_k127_9056109_24 Domain of unknown function (DUF1844) - - - 0.0000000000000000002224 93.0
PYH3_k127_9056109_25 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000003362 89.0
PYH3_k127_9056109_26 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000001336 68.0
PYH3_k127_9056109_27 PBS lyase HEAT-like repeat - - - 0.00000002158 68.0
PYH3_k127_9056109_28 Tetratricopeptide repeat protein - - - 0.0007616 52.0
PYH3_k127_9056109_3 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 474.0
PYH3_k127_9056109_4 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 468.0
PYH3_k127_9056109_5 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 407.0
PYH3_k127_9056109_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 376.0
PYH3_k127_9056109_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 331.0
PYH3_k127_9056109_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 287.0
PYH3_k127_9056109_9 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 280.0
PYH3_k127_9131855_0 glutamate synthase alpha subunit K00265 - 1.4.1.13,1.4.1.14 0.0 1729.0
PYH3_k127_9131855_1 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 434.0
PYH3_k127_9131855_2 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000001482 252.0
PYH3_k127_9131855_3 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000005588 234.0
PYH3_k127_9131855_4 - - - - 0.00000000000000003708 81.0
PYH3_k127_9198701_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 482.0
PYH3_k127_9198701_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 474.0
PYH3_k127_9198701_10 cyclic nucleotide binding K10914 - - 0.000000000000000002236 92.0
PYH3_k127_9198701_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000001408 90.0
PYH3_k127_9198701_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.0000000000000001942 83.0
PYH3_k127_9198701_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 361.0
PYH3_k127_9198701_3 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 326.0
PYH3_k127_9198701_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000003655 220.0
PYH3_k127_9198701_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000006344 153.0
PYH3_k127_9198701_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000001303 140.0
PYH3_k127_9198701_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000983 139.0
PYH3_k127_9198701_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.0000000000000000000000000000002861 139.0
PYH3_k127_9198701_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000003081 114.0
PYH3_k127_9223516_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.285e-213 665.0
PYH3_k127_9223516_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.159e-199 628.0
PYH3_k127_9223516_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
PYH3_k127_9223516_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004299 207.0
PYH3_k127_9223516_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000009909 205.0
PYH3_k127_9223516_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001313 208.0
PYH3_k127_9223516_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001006 198.0
PYH3_k127_9223516_15 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
PYH3_k127_9223516_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000005171 183.0
PYH3_k127_9223516_17 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001285 177.0
PYH3_k127_9223516_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000001679 174.0
PYH3_k127_9223516_19 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000001425 169.0
PYH3_k127_9223516_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 399.0
PYH3_k127_9223516_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000003406 152.0
PYH3_k127_9223516_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000004266 150.0
PYH3_k127_9223516_22 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001126 148.0
PYH3_k127_9223516_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000005534 137.0
PYH3_k127_9223516_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001572 132.0
PYH3_k127_9223516_25 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000009087 129.0
PYH3_k127_9223516_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000001325 112.0
PYH3_k127_9223516_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003229 104.0
PYH3_k127_9223516_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000005131 94.0
PYH3_k127_9223516_29 Ribosomal protein L36 K02919 - - 0.00000000000002691 72.0
PYH3_k127_9223516_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 391.0
PYH3_k127_9223516_30 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001283 66.0
PYH3_k127_9223516_31 Ribosomal protein L30 K02907 - - 0.0000000002721 69.0
PYH3_k127_9223516_32 - - - - 0.0000004916 57.0
PYH3_k127_9223516_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 322.0
PYH3_k127_9223516_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 295.0
PYH3_k127_9223516_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001451 282.0
PYH3_k127_9223516_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
PYH3_k127_9223516_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
PYH3_k127_9223516_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
PYH3_k127_9231516_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 538.0
PYH3_k127_9231516_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 332.0
PYH3_k127_9231516_10 Helix-hairpin-helix motif K02237 - - 0.0000000000000001681 83.0
PYH3_k127_9231516_11 Mo-molybdopterin cofactor metabolic process K03635,K03831,K09121 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75,2.8.1.12,4.99.1.12 0.000000000001043 74.0
PYH3_k127_9231516_12 dextransucrase activity K01728,K06324,K08100,K18197,K20276 GO:0005575,GO:0005576 1.16.3.3,1.3.3.5,4.2.2.2,4.2.2.23 0.00000000006234 77.0
PYH3_k127_9231516_13 PKD domain K09607,K19668 - 3.2.1.91 0.0000003137 65.0
PYH3_k127_9231516_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 293.0
PYH3_k127_9231516_3 stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001925 273.0
PYH3_k127_9231516_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000005436 191.0
PYH3_k127_9231516_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000001423 194.0
PYH3_k127_9231516_6 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000002259 170.0
PYH3_k127_9231516_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000003172 136.0
PYH3_k127_9231516_8 Kelch motif - - - 0.000000000000000000000000002657 131.0
PYH3_k127_9231516_9 ABC transporter K02065 - - 0.0000000000000000008713 87.0
PYH3_k127_9271773_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 3.253e-210 679.0
PYH3_k127_9271773_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 535.0
PYH3_k127_9271773_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000007213 241.0
PYH3_k127_9271773_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000001156 209.0
PYH3_k127_9271773_4 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000002184 119.0
PYH3_k127_9271773_5 oligosaccharyl transferase activity - - - 0.00000000000000000000001558 113.0
PYH3_k127_9298192_0 PFAM Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000001257 179.0
PYH3_k127_9298192_1 - - - - 0.000000000000000000000000000000000000000001295 165.0
PYH3_k127_9298192_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000003183 115.0
PYH3_k127_9298192_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00002879 53.0
PYH3_k127_9357381_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 430.0
PYH3_k127_9357381_1 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001326 195.0
PYH3_k127_9357381_2 lipolytic protein G-D-S-L family - - - 0.000005699 56.0
PYH3_k127_9390855_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 541.0
PYH3_k127_9390855_1 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 496.0
PYH3_k127_9390855_10 PilT protein domain protein - - - 0.00000000000000008766 85.0
PYH3_k127_9390855_11 OmpA family - - - 0.0001283 47.0
PYH3_k127_9390855_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 426.0
PYH3_k127_9390855_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001066 222.0
PYH3_k127_9390855_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000005554 213.0
PYH3_k127_9390855_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000002311 182.0
PYH3_k127_9390855_6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.0000000000000000000000000003456 130.0
PYH3_k127_9390855_7 oligosaccharyl transferase activity - - - 0.0000000000000000000000005177 121.0
PYH3_k127_9390855_8 PFAM Bacterial Ig-like domain (group 2) - - - 0.00000000000000000000007625 115.0
PYH3_k127_9390855_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000001361 113.0
PYH3_k127_9454497_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 2.183e-242 769.0
PYH3_k127_9454497_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 493.0
PYH3_k127_9454497_10 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000003246 229.0
PYH3_k127_9454497_11 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000006191 235.0
PYH3_k127_9454497_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000002434 237.0
PYH3_k127_9454497_13 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000001098 233.0
PYH3_k127_9454497_14 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000009739 218.0
PYH3_k127_9454497_15 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000001468 160.0
PYH3_k127_9454497_16 PFAM HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000001171 162.0
PYH3_k127_9454497_17 Protein of unknown function DUF58 - - - 0.000000000000000000000004729 117.0
PYH3_k127_9454497_18 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000008076 103.0
PYH3_k127_9454497_19 NusG domain II - - - 0.00000000000001861 78.0
PYH3_k127_9454497_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 474.0
PYH3_k127_9454497_22 Protein of unknown function (DUF4013) - - - 0.00000009085 64.0
PYH3_k127_9454497_23 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000028 59.0
PYH3_k127_9454497_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 391.0
PYH3_k127_9454497_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 392.0
PYH3_k127_9454497_5 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 347.0
PYH3_k127_9454497_6 ABC-2 family transporter protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 332.0
PYH3_k127_9454497_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 345.0
PYH3_k127_9454497_8 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 298.0
PYH3_k127_9454497_9 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004583 271.0
PYH3_k127_9459549_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.426e-251 816.0
PYH3_k127_9459549_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 345.0
PYH3_k127_9459549_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000005285 194.0
PYH3_k127_9459549_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000005951 175.0
PYH3_k127_9459549_4 lyase activity - - - 0.000000000000000000000000000000000000000000000008493 189.0
PYH3_k127_9459549_5 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000007383 161.0
PYH3_k127_9459549_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000004792 108.0
PYH3_k127_9459549_8 Domain of unknown function (DUF4388) - - - 0.0000003407 59.0
PYH3_k127_9534373_0 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 494.0
PYH3_k127_9534373_1 UDP binding domain K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 372.0
PYH3_k127_9534373_3 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000002612 193.0
PYH3_k127_9534373_4 Parallel beta-helix repeats - - - 0.000000000000000002406 98.0
PYH3_k127_9577314_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 586.0
PYH3_k127_9577314_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 486.0
PYH3_k127_9577314_10 TfoX N-terminal domain - - - 0.000000000000000000000000000000000001571 141.0
PYH3_k127_9577314_11 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.00000000000000000000005705 103.0
PYH3_k127_9577314_12 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000005702 99.0
PYH3_k127_9577314_13 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000007812 94.0
PYH3_k127_9577314_14 oligosaccharyl transferase activity - - - 0.0000000000000003869 91.0
PYH3_k127_9577314_15 Acetyltransferase (GNAT) domain - - - 0.00000002683 62.0
PYH3_k127_9577314_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000374 53.0
PYH3_k127_9577314_17 oligosaccharyl transferase activity - - - 0.00001681 50.0
PYH3_k127_9577314_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 483.0
PYH3_k127_9577314_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 458.0
PYH3_k127_9577314_4 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 426.0
PYH3_k127_9577314_5 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 379.0
PYH3_k127_9577314_6 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 356.0
PYH3_k127_9577314_7 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 349.0
PYH3_k127_9577314_8 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 346.0
PYH3_k127_9577314_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 297.0
PYH3_k127_9597573_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.389e-227 723.0
PYH3_k127_9597573_1 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 309.0
PYH3_k127_9597573_2 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000001008 220.0
PYH3_k127_9597573_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000002072 150.0
PYH3_k127_9597573_4 Two component signalling adaptor domain K03408 - - 0.0000000000000000002864 96.0
PYH3_k127_9597573_5 PFAM ApbE family lipoprotein K09740 - - 0.0001764 46.0
PYH3_k127_9686218_0 Nickel-dependent hydrogenase - - - 4.581e-205 646.0
PYH3_k127_9686218_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 548.0
PYH3_k127_9686218_10 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000232 207.0
PYH3_k127_9686218_11 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000007914 175.0
PYH3_k127_9686218_12 HI0933 family K07007 - - 0.0000000000000000000000000000000000006604 146.0
PYH3_k127_9686218_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000006959 156.0
PYH3_k127_9686218_14 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000000000000000002341 136.0
PYH3_k127_9686218_15 maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.00000000000000000000000001179 115.0
PYH3_k127_9686218_16 alkyl hydroperoxide reductase activity - - - 0.0000000003295 63.0
PYH3_k127_9686218_17 PFAM S-layer homology domain - - - 0.000297 51.0
PYH3_k127_9686218_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 473.0
PYH3_k127_9686218_3 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 416.0
PYH3_k127_9686218_4 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 414.0
PYH3_k127_9686218_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 336.0
PYH3_k127_9686218_6 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005603 279.0
PYH3_k127_9686218_7 PFAM NLP P60 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 267.0
PYH3_k127_9686218_8 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001306 249.0
PYH3_k127_9686218_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000055 233.0
PYH3_k127_9739123_0 Phosphoesterase family - - - 1.486e-233 748.0
PYH3_k127_9739123_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000006364 203.0
PYH3_k127_9754250_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.109e-209 666.0
PYH3_k127_9754250_1 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 534.0
PYH3_k127_9754250_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 406.0
PYH3_k127_9754250_3 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000004378 236.0
PYH3_k127_9754250_4 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000001152 208.0
PYH3_k127_9754250_5 Domain of unknown function (DUF1848) - - - 0.000000000000000000000000000000000000000002151 171.0
PYH3_k127_9754250_6 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000001004 143.0
PYH3_k127_9754942_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 525.0
PYH3_k127_9754942_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 491.0
PYH3_k127_9754942_10 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007153 247.0
PYH3_k127_9754942_11 NQR2, RnfD, RnfE family K03614 - - 0.0000000000000000000000000000000000000000000000000000002288 205.0
PYH3_k127_9754942_12 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000005617 198.0
PYH3_k127_9754942_13 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000003866 117.0
PYH3_k127_9754942_2 RnfC Barrel sandwich hybrid domain K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 470.0
PYH3_k127_9754942_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 462.0
PYH3_k127_9754942_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 408.0
PYH3_k127_9754942_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 402.0
PYH3_k127_9754942_6 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 383.0
PYH3_k127_9754942_7 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 308.0
PYH3_k127_9754942_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 289.0
PYH3_k127_9754942_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0