Overview

ID MAG03305
Name REGS1_bin.4
Sample SMP0079
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dormibacteria
Order Dormibacterales
Family Dormibacteraceae
Genus 40CM-4-65-16
Species
Assembly information
Completeness (%) 78.05
Contamination (%) 1.72
GC content (%) 67.0
N50 (bp) 12,658
Genome size (bp) 1,982,584

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1906

Gene name Description KEGG GOs EC E-value Score Sequence
REGS1_k127_10249_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 457.0
REGS1_k127_10249_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 434.0
REGS1_k127_10249_2 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000001019 226.0
REGS1_k127_10249_3 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000009738 87.0
REGS1_k127_10249_4 Helix-turn-helix XRE-family like proteins K20342,K20391 - - 0.0009356 49.0
REGS1_k127_108996_0 von Willebrand factor (vWF) type A domain K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 574.0
REGS1_k127_108996_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 484.0
REGS1_k127_108996_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000001676 127.0
REGS1_k127_108996_11 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000001348 94.0
REGS1_k127_108996_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 452.0
REGS1_k127_108996_3 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 391.0
REGS1_k127_108996_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000001893 241.0
REGS1_k127_108996_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002598 229.0
REGS1_k127_108996_6 AdoMet dependent proline di-methyltransferase - - - 0.000000000000000000000000000000000000014 155.0
REGS1_k127_108996_7 SnoaL-like domain - - - 0.00000000000000000000000000000000000002048 146.0
REGS1_k127_108996_8 oxidoreductase K00334 - 1.6.5.3 0.0000000000000000000000000000000000001226 150.0
REGS1_k127_108996_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000002686 135.0
REGS1_k127_116041_0 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 446.0
REGS1_k127_116041_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 410.0
REGS1_k127_116041_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000005199 114.0
REGS1_k127_116041_11 - - - - 0.000000000000000004031 88.0
REGS1_k127_116041_12 helix_turn_helix, mercury resistance - - - 0.00000000002429 72.0
REGS1_k127_116041_2 SMART von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 338.0
REGS1_k127_116041_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 313.0
REGS1_k127_116041_4 chorismate binding enzyme K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 278.0
REGS1_k127_116041_5 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001694 242.0
REGS1_k127_116041_6 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000002154 222.0
REGS1_k127_116041_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000001398 216.0
REGS1_k127_116041_8 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000000000000000000000000000000000001478 214.0
REGS1_k127_116041_9 CGNR zinc finger - - - 0.0000000000000000000000000000000000000000000897 165.0
REGS1_k127_1180150_0 1-deoxy-D-xylulose-5-phosphate synthase K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004644 274.0
REGS1_k127_1180150_1 ABC transporter K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000006966 226.0
REGS1_k127_1180150_2 Peptidase family M23 K21471 - - 0.0000000000000000000000000000005424 139.0
REGS1_k127_1180150_3 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000002768 94.0
REGS1_k127_1182132_0 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 554.0
REGS1_k127_1182132_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 445.0
REGS1_k127_1182132_2 organic acid phosphorylation K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 384.0
REGS1_k127_1182132_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 362.0
REGS1_k127_1182132_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000001579 215.0
REGS1_k127_1182132_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000009092 192.0
REGS1_k127_1182132_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000004438 169.0
REGS1_k127_1182132_7 Cyclic-di-AMP receptor - - - 0.000000000000000000000000002988 121.0
REGS1_k127_1182132_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000003089 116.0
REGS1_k127_1182132_9 Belongs to the UPF0234 family K09767 - - 0.00000000000000000001958 94.0
REGS1_k127_1187265_0 Cysteine-rich domain K21834 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 497.0
REGS1_k127_1187265_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 301.0
REGS1_k127_1205245_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 2.529e-235 751.0
REGS1_k127_1205245_1 S-adenosylhomocysteine deaminase activity K01485,K03365 GO:0003674,GO:0003824,GO:0004131,GO:0005488,GO:0005506,GO:0005515,GO:0006139,GO:0006206,GO:0006208,GO:0006209,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0019439,GO:0019858,GO:0034641,GO:0035888,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.4.1,3.5.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 472.0
REGS1_k127_1205245_10 Pfam:DUF46 - - - 0.00000000000000004368 91.0
REGS1_k127_1205245_11 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000008606 91.0
REGS1_k127_1205245_12 PFAM OsmC family protein - - - 0.0000000000000002745 87.0
REGS1_k127_1205245_13 Dolichol kinase K18678 GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006720,GO:0006721,GO:0006766,GO:0006775,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0010276,GO:0016101,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017144,GO:0018130,GO:0033306,GO:0034308,GO:0042360,GO:0042362,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1903173 2.7.1.182 0.000000001534 67.0
REGS1_k127_1205245_14 Dienelactone hydrolase - - - 0.000000004741 66.0
REGS1_k127_1205245_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000004227 56.0
REGS1_k127_1205245_16 PAS fold - - - 0.0009359 48.0
REGS1_k127_1205245_2 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 471.0
REGS1_k127_1205245_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 426.0
REGS1_k127_1205245_4 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000309 189.0
REGS1_k127_1205245_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000007539 168.0
REGS1_k127_1205245_6 Transthyretin K07127 - 3.5.2.17 0.0000000000000000000000000000001573 126.0
REGS1_k127_1205245_7 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000006791 113.0
REGS1_k127_1205245_8 sulfur carrier activity - - - 0.000000000000000000000009703 103.0
REGS1_k127_1205245_9 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000508 104.0
REGS1_k127_120978_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 503.0
REGS1_k127_120978_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000003219 226.0
REGS1_k127_120978_2 DNA methylase K00590 - 2.1.1.113 0.00000000000002689 82.0
REGS1_k127_1212450_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008893 288.0
REGS1_k127_1212450_1 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001559 252.0
REGS1_k127_1212450_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000001085 222.0
REGS1_k127_1212450_3 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
REGS1_k127_1212450_4 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000005058 152.0
REGS1_k127_1212740_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 457.0
REGS1_k127_1212740_1 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 313.0
REGS1_k127_1212740_2 ABC-2 family transporter protein - - - 0.0000000000000000000000001932 113.0
REGS1_k127_1214653_0 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 384.0
REGS1_k127_1214653_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 368.0
REGS1_k127_1214653_10 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000000000000000000000000000000000003679 157.0
REGS1_k127_1214653_11 Low molecular weight phosphotyrosine protein phosphatase K03741,K18701 - 1.20.4.1,2.8.4.2 0.0000000000000000000000000000000000001502 145.0
REGS1_k127_1214653_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000002514 147.0
REGS1_k127_1214653_13 phosphate transport regulator K07220 - - 0.000000000000000000000000000000003443 138.0
REGS1_k127_1214653_14 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000145 140.0
REGS1_k127_1214653_15 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000006544 130.0
REGS1_k127_1214653_16 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000003749 121.0
REGS1_k127_1214653_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000004584 125.0
REGS1_k127_1214653_18 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K10810 - 2.5.1.3,5.3.99.10 0.00000000000000000000007551 109.0
REGS1_k127_1214653_19 Monogalactosyldiacylglycerol (MGDG) synthase - - - 0.00000000000425 74.0
REGS1_k127_1214653_2 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 343.0
REGS1_k127_1214653_20 thiamine biosynthesis protein ThiS K03154 - - 0.00000000002853 69.0
REGS1_k127_1214653_21 Cytochrome b(C-terminal)/b6/petD K03888 - - 0.000008098 56.0
REGS1_k127_1214653_22 Periplasmic component of the Tol biopolymer transport system - - - 0.00001579 58.0
REGS1_k127_1214653_23 - - - - 0.0001863 54.0
REGS1_k127_1214653_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 310.0
REGS1_k127_1214653_4 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 313.0
REGS1_k127_1214653_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 306.0
REGS1_k127_1214653_6 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 311.0
REGS1_k127_1214653_7 Two component transcriptional regulator, winged helix family K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000003226 211.0
REGS1_k127_1214653_8 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000006239 201.0
REGS1_k127_1214653_9 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000006914 185.0
REGS1_k127_1261225_0 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000004323 215.0
REGS1_k127_1261225_1 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000001179 144.0
REGS1_k127_1261225_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000002931 86.0
REGS1_k127_1261225_3 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000004376 52.0
REGS1_k127_1267055_0 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K16012,K16014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 498.0
REGS1_k127_1267055_1 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013,K16014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 425.0
REGS1_k127_1267055_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000006345 136.0
REGS1_k127_1267055_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00001125 51.0
REGS1_k127_1267055_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00001386 53.0
REGS1_k127_1267618_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 575.0
REGS1_k127_1267618_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 348.0
REGS1_k127_1267618_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 324.0
REGS1_k127_1267618_3 FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000000000000000000000001048 179.0
REGS1_k127_1267618_4 alpha-ribazole phosphatase activity K01834,K02226,K03574,K15634 - 3.1.3.73,3.6.1.55,5.4.2.11,5.4.2.12 0.0000000000000000000004443 104.0
REGS1_k127_1267618_5 FtsZ-dependent cytokinesis - - - 0.0000000000000000001662 98.0
REGS1_k127_1267618_6 Thioesterase superfamily - - - 0.00000000000000002928 86.0
REGS1_k127_1299043_0 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 444.0
REGS1_k127_1299043_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006482 250.0
REGS1_k127_1299043_2 NhaP-type Na H and K H K03316 - - 0.0000000000000000000000000000000000000000000000000000000000001761 227.0
REGS1_k127_1299043_3 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000008591 210.0
REGS1_k127_1299043_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000001825 130.0
REGS1_k127_1299043_5 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000002084 114.0
REGS1_k127_1299043_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000001102 68.0
REGS1_k127_130997_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 518.0
REGS1_k127_130997_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 464.0
REGS1_k127_130997_10 HhH-GPD superfamily base excision DNA repair protein - - - 0.0001278 45.0
REGS1_k127_130997_11 RNA polymerase K03088 - - 0.0003759 47.0
REGS1_k127_130997_2 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 397.0
REGS1_k127_130997_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 362.0
REGS1_k127_130997_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 296.0
REGS1_k127_130997_5 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000006318 272.0
REGS1_k127_130997_6 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001382 258.0
REGS1_k127_130997_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000426 177.0
REGS1_k127_130997_8 PFAM HhH-GPD family protein - - - 0.000000000000000000000000000000000000001634 151.0
REGS1_k127_130997_9 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.0000000000000000000000000000004215 129.0
REGS1_k127_132555_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 7.704e-210 676.0
REGS1_k127_132555_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 475.0
REGS1_k127_132555_10 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000007027 210.0
REGS1_k127_132555_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000003485 200.0
REGS1_k127_132555_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000001763 204.0
REGS1_k127_132555_13 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000003196 180.0
REGS1_k127_132555_14 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000003459 145.0
REGS1_k127_132555_15 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000005186 74.0
REGS1_k127_132555_16 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000001842 56.0
REGS1_k127_132555_2 magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 437.0
REGS1_k127_132555_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 398.0
REGS1_k127_132555_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 335.0
REGS1_k127_132555_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
REGS1_k127_132555_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 316.0
REGS1_k127_132555_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001251 269.0
REGS1_k127_132555_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 256.0
REGS1_k127_132555_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
REGS1_k127_1340996_0 Peptidase M16C associated K06972 - - 3.141e-284 910.0
REGS1_k127_1340996_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 489.0
REGS1_k127_1340996_10 Asp23 family, cell envelope-related function - - - 0.000000000000000000000007394 106.0
REGS1_k127_1340996_11 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000003287 96.0
REGS1_k127_1340996_12 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000003885 76.0
REGS1_k127_1340996_13 pyridoxamine 5-phosphate K05558 - - 0.000000000002088 70.0
REGS1_k127_1340996_14 membrane - - - 0.0000000001251 72.0
REGS1_k127_1340996_16 - - - - 0.0004185 44.0
REGS1_k127_1340996_2 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 398.0
REGS1_k127_1340996_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 355.0
REGS1_k127_1340996_4 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 358.0
REGS1_k127_1340996_5 PFAM histone deacetylase superfamily K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 343.0
REGS1_k127_1340996_6 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000206 227.0
REGS1_k127_1340996_7 PFAM Formiminotransferase K00603,K01746 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000001679 203.0
REGS1_k127_1340996_8 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000001248 165.0
REGS1_k127_1340996_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000003023 163.0
REGS1_k127_13634_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 1.01e-208 659.0
REGS1_k127_1394607_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1252.0
REGS1_k127_1394607_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 519.0
REGS1_k127_1394607_10 transmembrane transport K01992,K09696 - - 0.000000000000000000000000000000000003342 154.0
REGS1_k127_1394607_11 - - - - 0.00000000000000000000000000001156 124.0
REGS1_k127_1394607_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175,K13713 - 2.1.2.2,6.3.2.6,6.3.4.13 0.00000000000000000000000000138 115.0
REGS1_k127_1394607_13 ABC transporter K01990 - - 0.00000001246 60.0
REGS1_k127_1394607_14 cyclase dehydrase - - - 0.000001864 56.0
REGS1_k127_1394607_15 - - - - 0.000002118 58.0
REGS1_k127_1394607_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 498.0
REGS1_k127_1394607_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009267,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009987,GO:0009991,GO:0016036,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0034654,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 383.0
REGS1_k127_1394607_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 334.0
REGS1_k127_1394607_5 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 302.0
REGS1_k127_1394607_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 280.0
REGS1_k127_1394607_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000009774 198.0
REGS1_k127_1394607_8 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000006569 196.0
REGS1_k127_1394607_9 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000004003 165.0
REGS1_k127_1403896_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 546.0
REGS1_k127_1403896_1 Acetylornithine deacetylase K01439,K05831 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 463.0
REGS1_k127_1403896_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002215 279.0
REGS1_k127_1403896_3 PFAM peptidase S58 DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 275.0
REGS1_k127_1403896_4 alpha-ribazole phosphatase activity K01834,K02226,K03574,K15634 - 3.1.3.73,3.6.1.55,5.4.2.11,5.4.2.12 0.0000000000000000000000000000000000000000000000000000002435 202.0
REGS1_k127_1403896_5 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000008161 174.0
REGS1_k127_1403896_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000001565 121.0
REGS1_k127_1441251_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 590.0
REGS1_k127_1441251_1 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000001417 147.0
REGS1_k127_1441251_2 Bacterial lipid A biosynthesis acyltransferase K22311 - 2.3.1.265 0.0000000000000000000000000000001078 135.0
REGS1_k127_1441251_3 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000425 83.0
REGS1_k127_1441251_4 DNA-binding transcription factor activity K03892 - - 0.00000000008379 67.0
REGS1_k127_152946_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000001816 156.0
REGS1_k127_152946_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000003806 91.0
REGS1_k127_152946_2 Phosphoenolpyruvate hydrolase-like - - - 0.0009163 43.0
REGS1_k127_1531606_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000347 211.0
REGS1_k127_1531606_1 - - - - 0.000000000000000000000000000000000000000000000000001254 190.0
REGS1_k127_1531606_2 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000000000000000000000000003593 129.0
REGS1_k127_1531606_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000001638 65.0
REGS1_k127_1531606_4 Polymer-forming cytoskeletal - - - 0.00005823 51.0
REGS1_k127_1578600_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004711 292.0
REGS1_k127_1578600_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000009227 93.0
REGS1_k127_1578600_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000006813 77.0
REGS1_k127_1615496_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1319.0
REGS1_k127_1615496_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.451e-278 865.0
REGS1_k127_1615496_10 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 417.0
REGS1_k127_1615496_11 HMGL-like K18314 - 4.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 405.0
REGS1_k127_1615496_12 deiminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 387.0
REGS1_k127_1615496_13 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
REGS1_k127_1615496_14 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 377.0
REGS1_k127_1615496_15 CYTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 347.0
REGS1_k127_1615496_16 transporter mgtE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002941 292.0
REGS1_k127_1615496_17 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008206 245.0
REGS1_k127_1615496_18 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000075 227.0
REGS1_k127_1615496_19 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000007556 223.0
REGS1_k127_1615496_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.244e-235 747.0
REGS1_k127_1615496_20 - - - - 0.000000000000000000000000000000000000000000000000000000006697 213.0
REGS1_k127_1615496_21 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000003049 156.0
REGS1_k127_1615496_22 PBP superfamily domain - - - 0.00000000000000000000000000000000000001421 156.0
REGS1_k127_1615496_23 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.00000000000000000000000000000003459 136.0
REGS1_k127_1615496_24 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000005312 127.0
REGS1_k127_1615496_25 Cation efflux family - - - 0.000000000000000000000000001587 126.0
REGS1_k127_1615496_26 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000693 109.0
REGS1_k127_1615496_27 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000001156 98.0
REGS1_k127_1615496_28 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000007132 74.0
REGS1_k127_1615496_29 Glycosyltransferase family 87 - - - 0.0000000000008332 80.0
REGS1_k127_1615496_3 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 3.677e-201 634.0
REGS1_k127_1615496_30 - - - - 0.000000000003271 76.0
REGS1_k127_1615496_31 - - - - 0.00000001221 61.0
REGS1_k127_1615496_32 Helix-turn-helix XRE-family like proteins - - - 0.0000002827 57.0
REGS1_k127_1615496_33 Polyketide cyclase / dehydrase and lipid transport - - - 0.000003085 57.0
REGS1_k127_1615496_34 metal-sulfur cluster biosynthetic enzyme - - - 0.000009283 51.0
REGS1_k127_1615496_35 CAAX protease self-immunity - - - 0.00001179 55.0
REGS1_k127_1615496_36 Flp Fap pilin component - - - 0.00003161 49.0
REGS1_k127_1615496_37 PFAM WD40 domain protein beta Propeller K03641 - - 0.00008184 52.0
REGS1_k127_1615496_38 RDD family - - - 0.0002958 51.0
REGS1_k127_1615496_39 Pyridoxamine 5'-phosphate oxidase - - - 0.0003834 51.0
REGS1_k127_1615496_4 H( )-stimulated, divalent metal cation uptake system - - - 2.497e-198 631.0
REGS1_k127_1615496_40 DUF167 K09131 - - 0.0003961 46.0
REGS1_k127_1615496_41 Cro/C1-type HTH DNA-binding domain - - - 0.0008573 46.0
REGS1_k127_1615496_5 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 604.0
REGS1_k127_1615496_6 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 586.0
REGS1_k127_1615496_7 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299,K03281 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 563.0
REGS1_k127_1615496_8 alpha amylase, catalytic K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 466.0
REGS1_k127_1615496_9 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 417.0
REGS1_k127_16359_0 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 449.0
REGS1_k127_16359_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000001856 263.0
REGS1_k127_16359_2 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000004546 211.0
REGS1_k127_164047_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 1048.0
REGS1_k127_164047_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000001297 117.0
REGS1_k127_1671586_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 351.0
REGS1_k127_1671586_1 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 329.0
REGS1_k127_1671586_2 Small multidrug resistance protein K03297 - - 0.000004673 49.0
REGS1_k127_1686421_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 321.0
REGS1_k127_1686421_1 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006401 260.0
REGS1_k127_1686421_2 cheY-homologous receiver domain - - - 0.000000000000000000000000001777 124.0
REGS1_k127_1793484_0 Succinyl-CoA ligase like flavodoxin domain - - - 1.979e-279 887.0
REGS1_k127_1793484_1 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 3.208e-210 673.0
REGS1_k127_1793484_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001049 285.0
REGS1_k127_1793484_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007839 249.0
REGS1_k127_1793484_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000001594 237.0
REGS1_k127_1793484_5 CBS-domain-containing membrane protein - - - 0.00000000000000001537 88.0
REGS1_k127_1793484_6 Histidine kinase - - - 0.00000000000136 70.0
REGS1_k127_1793484_7 - - - - 0.0001171 48.0
REGS1_k127_1863563_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.881e-273 870.0
REGS1_k127_1863563_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 442.0
REGS1_k127_1863563_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000001795 164.0
REGS1_k127_1863563_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000003649 175.0
REGS1_k127_1863563_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000001413 150.0
REGS1_k127_1863563_13 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.0000000000000000000002445 103.0
REGS1_k127_1863563_14 YGGT family K02221 - - 0.00000000002096 68.0
REGS1_k127_1863563_15 DinB superfamily - - - 0.0001297 52.0
REGS1_k127_1863563_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 404.0
REGS1_k127_1863563_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 367.0
REGS1_k127_1863563_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 327.0
REGS1_k127_1863563_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000003448 273.0
REGS1_k127_1863563_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
REGS1_k127_1863563_7 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000001888 187.0
REGS1_k127_1863563_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000001225 178.0
REGS1_k127_1863563_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000004137 170.0
REGS1_k127_1910251_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000002194 229.0
REGS1_k127_1910251_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
REGS1_k127_1941642_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 412.0
REGS1_k127_1941642_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
REGS1_k127_1941642_2 phosphate transport system permease protein K02037,K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051704,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000007382 256.0
REGS1_k127_1941642_3 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001588 208.0
REGS1_k127_1941642_4 Ribosomal RNA small subunit methyltransferase K03501 - 2.1.1.170 0.00000000000000000000000000000000000003801 151.0
REGS1_k127_1941642_5 Regulatory protein, FmdB - - - 0.0000000009636 63.0
REGS1_k127_1973829_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 567.0
REGS1_k127_1973829_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 556.0
REGS1_k127_1973829_2 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 417.0
REGS1_k127_1973829_3 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
REGS1_k127_1973829_4 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000009081 141.0
REGS1_k127_1973829_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000007265 86.0
REGS1_k127_1973829_6 - - - - 0.0000000003905 70.0
REGS1_k127_205914_0 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 286.0
REGS1_k127_205914_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002045 283.0
REGS1_k127_205914_2 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000001764 246.0
REGS1_k127_205914_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000004953 233.0
REGS1_k127_205914_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001078 215.0
REGS1_k127_205914_5 TM2 domain - - - 0.000000000000000000001003 99.0
REGS1_k127_205914_6 2-phospho-L-lactate guanylyltransferase K14941 - 2.7.7.68 0.0000000000000000001069 97.0
REGS1_k127_205914_7 Yqey-like protein - - - 0.000000000000000000379 98.0
REGS1_k127_21206_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.941e-209 663.0
REGS1_k127_21206_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 550.0
REGS1_k127_21206_10 Multidrug ABC transporter permease - - - 0.0000000000000000000000000000002437 133.0
REGS1_k127_21206_11 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000001281 87.0
REGS1_k127_21206_12 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000005029 81.0
REGS1_k127_21206_14 40-residue YVTN family beta-propeller repeat - - - 0.0003177 52.0
REGS1_k127_21206_2 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 359.0
REGS1_k127_21206_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 314.0
REGS1_k127_21206_4 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 322.0
REGS1_k127_21206_5 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000001603 237.0
REGS1_k127_21206_6 collagen metabolic process K08677 - - 0.00000000000000000000000000000000000000000000000000000000000000008097 243.0
REGS1_k127_21206_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000002638 224.0
REGS1_k127_21206_9 peptidase activity - - - 0.000000000000000000000000000000000000000004341 173.0
REGS1_k127_212834_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 4.067e-234 731.0
REGS1_k127_212834_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 477.0
REGS1_k127_212834_10 Transcriptional regulator - - - 0.0000000000000000000000000003325 123.0
REGS1_k127_212834_11 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000000000005451 100.0
REGS1_k127_212834_12 Rhodanese Homology Domain - - - 0.00000000000000000000971 95.0
REGS1_k127_212834_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 385.0
REGS1_k127_212834_3 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 367.0
REGS1_k127_212834_4 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 329.0
REGS1_k127_212834_5 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 335.0
REGS1_k127_212834_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 328.0
REGS1_k127_212834_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 245.0
REGS1_k127_212834_8 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000006793 178.0
REGS1_k127_212834_9 Pfam:DUF59 - - - 0.000000000000000000000000000002962 124.0
REGS1_k127_2213826_0 PFAM Transketolase central region K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 462.0
REGS1_k127_2213826_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 429.0
REGS1_k127_2213826_10 amino acid - - - 0.00000000000000000000005211 107.0
REGS1_k127_2213826_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 418.0
REGS1_k127_2213826_3 PFAM Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 327.0
REGS1_k127_2213826_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 304.0
REGS1_k127_2213826_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 293.0
REGS1_k127_2213826_6 PFAM dehydrogenase, E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000002101 239.0
REGS1_k127_2213826_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000005785 229.0
REGS1_k127_2213826_8 May be required for sporulation K09762 - - 0.0000000000000000000000000000000000000000000005886 178.0
REGS1_k127_2213826_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000001425 134.0
REGS1_k127_2290127_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 477.0
REGS1_k127_2290127_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000005484 172.0
REGS1_k127_2290127_2 ECF sigma factor K03088 - - 0.00000002049 61.0
REGS1_k127_2313141_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
REGS1_k127_2313141_1 Beta-phosphoglucomutase family hydrolase - GO:0003674,GO:0003824,GO:0008801,GO:0016853,GO:0016866,GO:0016868 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 321.0
REGS1_k127_2313141_2 hydrolase, family 65, central catalytic K05342 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.64 0.000000000000000000000000000000000000000000000000000000000000000002177 232.0
REGS1_k127_2321247_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 534.0
REGS1_k127_2321247_1 Ribosomal protein S1-like RNA-binding domain K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 309.0
REGS1_k127_2321247_2 O-Antigen ligase K02847 - - 0.00003851 56.0
REGS1_k127_2321247_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0001273 45.0
REGS1_k127_2338791_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.119e-260 819.0
REGS1_k127_2338791_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 303.0
REGS1_k127_2338791_2 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000003295 143.0
REGS1_k127_2338791_3 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000005018 89.0
REGS1_k127_2374757_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.465e-210 681.0
REGS1_k127_2374757_1 Cell division protein FtsA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 303.0
REGS1_k127_2374757_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654,K10966 - 3.4.23.43 0.0000000000000552 80.0
REGS1_k127_2374757_11 Bacterial PH domain - - - 0.0000000000006696 76.0
REGS1_k127_2374757_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000006141 253.0
REGS1_k127_2374757_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000001809 213.0
REGS1_k127_2374757_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000005875 198.0
REGS1_k127_2374757_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.000000000000000000000000000000000000000000000003625 182.0
REGS1_k127_2374757_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000009698 185.0
REGS1_k127_2374757_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000004181 169.0
REGS1_k127_2374757_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000002343 125.0
REGS1_k127_2374757_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000003625 116.0
REGS1_k127_2394525_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 1.782e-266 850.0
REGS1_k127_2394525_1 Belongs to the transketolase family K00615 - 2.2.1.1 4.582e-264 827.0
REGS1_k127_2394525_2 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 580.0
REGS1_k127_2394525_3 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 339.0
REGS1_k127_2394525_4 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 310.0
REGS1_k127_2394525_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000002491 182.0
REGS1_k127_2394525_6 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000001252 83.0
REGS1_k127_2412296_0 4-alpha-glucanotransferase K00700,K00705,K02438,K06044 - 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 501.0
REGS1_k127_2412296_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 403.0
REGS1_k127_2412296_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000005235 227.0
REGS1_k127_2426725_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 7.958e-215 682.0
REGS1_k127_2426725_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000002341 143.0
REGS1_k127_2426725_2 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000005498 130.0
REGS1_k127_2455984_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 448.0
REGS1_k127_2455984_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000008816 191.0
REGS1_k127_2455984_2 Belongs to the FPP GGPP synthase family K00805,K21275 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 0.0000000000000000000000000000000000000000000003736 184.0
REGS1_k127_2455984_3 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000003196 118.0
REGS1_k127_2455984_4 Bacterial regulatory proteins, tetR family - - - 0.0000000004794 68.0
REGS1_k127_2461891_0 synthase K06044 - 5.4.99.15 5.692e-258 819.0
REGS1_k127_2461891_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 295.0
REGS1_k127_249418_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009417 283.0
REGS1_k127_249418_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000001442 147.0
REGS1_k127_249418_2 PFAM Sporulation and spore germination - - - 0.00000000000001304 80.0
REGS1_k127_2544114_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 2.234e-206 652.0
REGS1_k127_2544114_1 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 534.0
REGS1_k127_2544114_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000001973 84.0
REGS1_k127_2544114_11 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000004688 73.0
REGS1_k127_2544114_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000005533 64.0
REGS1_k127_2544114_13 LppX_LprAFG lipoprotein K14954,K14955 GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561 - 0.0000365 55.0
REGS1_k127_2544114_2 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 428.0
REGS1_k127_2544114_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 333.0
REGS1_k127_2544114_4 - - - - 0.000000000000000000000000000000000000000000000000000000008427 202.0
REGS1_k127_2544114_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000001264 136.0
REGS1_k127_2544114_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000001734 120.0
REGS1_k127_2544114_7 Peptidase family M23 - - - 0.000000000000000000000009329 114.0
REGS1_k127_2544114_8 SPTR D1C1B9 DinB family protein - - - 0.000000000000000000009212 106.0
REGS1_k127_2544114_9 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000009071 79.0
REGS1_k127_2562415_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 448.0
REGS1_k127_2562415_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 385.0
REGS1_k127_2562415_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 344.0
REGS1_k127_2562415_3 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 324.0
REGS1_k127_2564116_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 336.0
REGS1_k127_2564116_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000006021 244.0
REGS1_k127_2564116_2 transcriptional regulator K03892 - - 0.000000000000000001257 90.0
REGS1_k127_2564116_3 Fic/DOC family - - - 0.0000004037 55.0
REGS1_k127_2564116_4 mRNA transport K14320 GO:0000003,GO:0003008,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005737,GO:0005783,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006810,GO:0006913,GO:0007610,GO:0007611,GO:0007612,GO:0008150,GO:0009566,GO:0012505,GO:0015630,GO:0016020,GO:0019953,GO:0022414,GO:0031090,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046907,GO:0050877,GO:0050890,GO:0051169,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0070013 - 0.0001134 54.0
REGS1_k127_2584437_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 468.0
REGS1_k127_2584437_1 Thi4 family K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 436.0
REGS1_k127_2584437_10 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000008883 158.0
REGS1_k127_2584437_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000009002 142.0
REGS1_k127_2584437_12 protein histidine kinase activity K10819 - 2.7.13.3 0.000000000000000000000003433 121.0
REGS1_k127_2584437_13 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000001338 107.0
REGS1_k127_2584437_14 thioesterase - - - 0.00000000000000002369 87.0
REGS1_k127_2584437_15 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.000000000000093 82.0
REGS1_k127_2584437_16 Belongs to the peptidase S51 family - - - 0.000000000006057 77.0
REGS1_k127_2584437_17 helix_turn_helix ASNC type - - - 0.000108 48.0
REGS1_k127_2584437_18 Histidine kinase - - - 0.0001081 56.0
REGS1_k127_2584437_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 402.0
REGS1_k127_2584437_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 358.0
REGS1_k127_2584437_4 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 323.0
REGS1_k127_2584437_5 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 327.0
REGS1_k127_2584437_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 301.0
REGS1_k127_2584437_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001421 190.0
REGS1_k127_2584437_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000003268 181.0
REGS1_k127_2584437_9 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000156 170.0
REGS1_k127_2661576_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 425.0
REGS1_k127_2661576_1 flavoprotein involved in K transport K07222 - - 0.00000000000000000000002358 106.0
REGS1_k127_2661576_2 - - - - 0.000005221 56.0
REGS1_k127_2661576_3 Histidine kinase - - - 0.00003746 53.0
REGS1_k127_2670928_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.808e-194 632.0
REGS1_k127_2670928_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 567.0
REGS1_k127_2670928_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
REGS1_k127_2670928_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000003599 101.0
REGS1_k127_269574_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.496e-223 704.0
REGS1_k127_269574_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 526.0
REGS1_k127_269574_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000008973 178.0
REGS1_k127_269574_11 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000002346 151.0
REGS1_k127_269574_12 NUDIX hydrolase - - - 0.000000000000000000000000008853 121.0
REGS1_k127_269574_13 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000149 110.0
REGS1_k127_269574_14 PFAM PHA accumulation regulator DNA-binding protein - - - 0.00000000000000000001196 98.0
REGS1_k127_269574_15 Domain of unknown function (DUF4332) - - - 0.0000001368 61.0
REGS1_k127_269574_16 Bacterial protein of unknown function (DUF881) - - - 0.0000002191 62.0
REGS1_k127_269574_17 Bacterial protein of unknown function (DUF881) - - - 0.0000002808 61.0
REGS1_k127_269574_18 WD40-like Beta Propeller Repeat - - - 0.0004509 53.0
REGS1_k127_269574_2 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 515.0
REGS1_k127_269574_3 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 498.0
REGS1_k127_269574_4 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 449.0
REGS1_k127_269574_5 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 418.0
REGS1_k127_269574_6 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 392.0
REGS1_k127_269574_7 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 301.0
REGS1_k127_269574_8 PFAM NAD-dependent epimerase dehydratase K01784 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000003297 235.0
REGS1_k127_269574_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006601 231.0
REGS1_k127_2758249_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 6.887e-199 643.0
REGS1_k127_2758249_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 368.0
REGS1_k127_2758249_2 Family 5 K15580 - - 0.0000000000000000000000000000000000000000000000000004125 209.0
REGS1_k127_2758249_3 Family 5 K15580 - - 0.0000000000000000000000000000000000000000000004657 192.0
REGS1_k127_2758249_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000009802 61.0
REGS1_k127_2766319_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 288.0
REGS1_k127_2766319_1 Small Multidrug Resistance protein K03297 - - 0.00000000000000000002542 101.0
REGS1_k127_2797215_0 OmpA family - - - 0.0 1758.0
REGS1_k127_2797215_1 Domain of unknown function DUF11 - - - 0.0 1378.0
REGS1_k127_2797215_2 Tetratricopeptide repeat - - - 1.26e-212 675.0
REGS1_k127_2797215_3 - - - - 0.00000000000000000000000000000000000000000000000003102 186.0
REGS1_k127_2820181_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 347.0
REGS1_k127_2820181_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001722 279.0
REGS1_k127_2820181_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000007288 246.0
REGS1_k127_2820181_3 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000004355 169.0
REGS1_k127_29730_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 7.597e-240 755.0
REGS1_k127_29730_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 313.0
REGS1_k127_29730_2 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003258 277.0
REGS1_k127_29730_3 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000014 232.0
REGS1_k127_29730_4 PFAM Type II IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000205 235.0
REGS1_k127_29730_5 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000002022 145.0
REGS1_k127_29730_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000004613 153.0
REGS1_k127_29730_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000006456 106.0
REGS1_k127_29730_8 type II secretion system K12510 - - 0.00000000008146 73.0
REGS1_k127_29730_9 Type II secretion system K12511 - - 0.00002928 55.0
REGS1_k127_298902_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 517.0
REGS1_k127_298902_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 444.0
REGS1_k127_298902_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 393.0
REGS1_k127_298902_3 Phosphopantetheine attachment site - - - 0.0000000000001284 74.0
REGS1_k127_3135370_0 A circularly permuted ATPgrasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 560.0
REGS1_k127_3135370_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 559.0
REGS1_k127_3135370_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 322.0
REGS1_k127_3135370_3 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000001078 257.0
REGS1_k127_3135370_4 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000002571 239.0
REGS1_k127_3135370_5 transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000004187 198.0
REGS1_k127_3135370_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000003599 183.0
REGS1_k127_3135370_7 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000003429 126.0
REGS1_k127_3135370_8 YCII-related domain - - - 0.0000000000000000000003152 99.0
REGS1_k127_336706_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 366.0
REGS1_k127_336706_1 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000001152 203.0
REGS1_k127_336706_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000005978 124.0
REGS1_k127_336706_3 Belongs to the eIF-2B alpha beta delta subunits family - - - 0.0002357 51.0
REGS1_k127_3417776_0 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 434.0
REGS1_k127_3417776_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000004097 240.0
REGS1_k127_3417776_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000001929 146.0
REGS1_k127_3417776_3 formate dehydrogenase (NAD+) activity K00123,K05299,K22015 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.10,1.17.1.9,1.17.99.7 0.000000000000004472 77.0
REGS1_k127_3470831_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 327.0
REGS1_k127_3470831_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002447 285.0
REGS1_k127_3470831_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000003322 248.0
REGS1_k127_3470831_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000001212 234.0
REGS1_k127_3470831_4 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000004856 221.0
REGS1_k127_3470831_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000002335 203.0
REGS1_k127_3470831_6 cyclic nucleotide-binding domain - - - 0.000000000000000000000000000000004539 149.0
REGS1_k127_3470831_7 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000000001594 142.0
REGS1_k127_3470831_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00003771 48.0
REGS1_k127_3486751_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.904e-283 893.0
REGS1_k127_3486751_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.739e-259 812.0
REGS1_k127_3486751_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 307.0
REGS1_k127_3486751_11 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 291.0
REGS1_k127_3486751_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002064 282.0
REGS1_k127_3486751_13 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000001691 208.0
REGS1_k127_3486751_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000007011 151.0
REGS1_k127_3486751_15 Transcriptional regulatory protein, C terminal K02483,K07669 - - 0.00000000000000000000000000000000000005945 151.0
REGS1_k127_3486751_16 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000003131 143.0
REGS1_k127_3486751_17 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.0000000000000000000000000000000003953 143.0
REGS1_k127_3486751_18 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000000000000000006185 132.0
REGS1_k127_3486751_19 CAAX protease self-immunity - - - 0.0000000000000000000000000001023 129.0
REGS1_k127_3486751_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 563.0
REGS1_k127_3486751_20 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000008798 109.0
REGS1_k127_3486751_21 Signal transduction histidine kinase K07777 - 2.7.13.3 0.000000000000000000000002176 113.0
REGS1_k127_3486751_22 Sigma-70 factor, region 1.2 K03086 - - 0.0000000001268 70.0
REGS1_k127_3486751_23 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000003417 59.0
REGS1_k127_3486751_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0001531 49.0
REGS1_k127_3486751_25 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.0008194 49.0
REGS1_k127_3486751_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 472.0
REGS1_k127_3486751_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 460.0
REGS1_k127_3486751_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 393.0
REGS1_k127_3486751_6 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 366.0
REGS1_k127_3486751_7 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 329.0
REGS1_k127_3486751_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 317.0
REGS1_k127_3486751_9 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 314.0
REGS1_k127_3501158_0 ABC transporter K06147 - - 6.33e-221 706.0
REGS1_k127_3501158_1 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000003036 215.0
REGS1_k127_3501158_2 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000001943 115.0
REGS1_k127_3501158_3 - - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000005645 106.0
REGS1_k127_3501158_4 - - - - 0.000000000000000001604 92.0
REGS1_k127_3560243_0 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000002599 210.0
REGS1_k127_3560243_1 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000005252 161.0
REGS1_k127_3560243_2 - - - - 0.0000000000000000000000000000000000002341 143.0
REGS1_k127_3569512_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 536.0
REGS1_k127_3569512_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 390.0
REGS1_k127_3569512_10 Peptidase family M50 - - - 0.000000000000000000002151 106.0
REGS1_k127_3569512_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000003292 73.0
REGS1_k127_3569512_2 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 417.0
REGS1_k127_3569512_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 388.0
REGS1_k127_3569512_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 377.0
REGS1_k127_3569512_5 CTP:tRNA cytidylyltransferase activity K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 298.0
REGS1_k127_3569512_6 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000009301 246.0
REGS1_k127_3569512_7 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000005585 208.0
REGS1_k127_3569512_8 metallochaperone-like domain K07402 - - 0.00000000000000000000000000000000000005126 150.0
REGS1_k127_3569512_9 Protein of unknown function (DUF1003) - - - 0.000000000000000000000005183 108.0
REGS1_k127_3665065_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 573.0
REGS1_k127_3665065_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 500.0
REGS1_k127_3665065_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000003882 226.0
REGS1_k127_3665065_3 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000003805 190.0
REGS1_k127_3665065_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000008866 158.0
REGS1_k127_3665065_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000008877 148.0
REGS1_k127_3665065_6 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000004231 145.0
REGS1_k127_3665065_7 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000001963 125.0
REGS1_k127_3665065_8 Multicopper oxidase - - - 0.00000004926 64.0
REGS1_k127_3671760_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 356.0
REGS1_k127_3671760_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 316.0
REGS1_k127_3671760_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000006344 155.0
REGS1_k127_3671760_11 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000000000000000479 158.0
REGS1_k127_3671760_12 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.0000000000000000000000007745 111.0
REGS1_k127_3671760_13 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000661 113.0
REGS1_k127_3671760_14 N-terminal half of MaoC dehydratase - - - 0.00000000000441 76.0
REGS1_k127_3671760_15 Pfam Major Facilitator Superfamily K08223 - - 0.000000001327 70.0
REGS1_k127_3671760_2 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 293.0
REGS1_k127_3671760_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000223 280.0
REGS1_k127_3671760_4 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000045 279.0
REGS1_k127_3671760_5 NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000006168 243.0
REGS1_k127_3671760_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
REGS1_k127_3671760_7 Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway K15525 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016137,GO:0016138,GO:0016787,GO:0016810,GO:0016811,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 3.5.1.103 0.0000000000000000000000000000000000000000000000000000000002654 211.0
REGS1_k127_3671760_8 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000005456 171.0
REGS1_k127_3671760_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08256 - 2.4.1.345,2.7.8.5 0.0000000000000000000000000000000000000001316 158.0
REGS1_k127_3716828_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000009821 230.0
REGS1_k127_3716828_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000001882 198.0
REGS1_k127_3716828_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000267 165.0
REGS1_k127_3716828_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000002977 89.0
REGS1_k127_3716828_4 Putative diguanylate phosphodiesterase - - - 0.00000000001419 72.0
REGS1_k127_3716828_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00001355 51.0
REGS1_k127_373967_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 319.0
REGS1_k127_373967_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 297.0
REGS1_k127_373967_10 protein secretion K03116 - - 0.0000000004727 63.0
REGS1_k127_373967_11 - - - - 0.000007168 48.0
REGS1_k127_373967_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003182 265.0
REGS1_k127_373967_3 Polyprenyl synthetase K00805,K21275 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 0.00000000000000000000000000000000000000000000000000000000003367 225.0
REGS1_k127_373967_4 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000002167 198.0
REGS1_k127_373967_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000009919 178.0
REGS1_k127_373967_6 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000005218 155.0
REGS1_k127_373967_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000007275 132.0
REGS1_k127_373967_8 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.000000000000000000000004512 110.0
REGS1_k127_373967_9 Zincin-like metallopeptidase - - - 0.00000000000000001624 87.0
REGS1_k127_377255_0 FGGY family of carbohydrate kinases, N-terminal domain K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 541.0
REGS1_k127_377255_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 498.0
REGS1_k127_377255_2 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009342 267.0
REGS1_k127_377255_3 SnoaL-like polyketide cyclase - - - 0.0000000000009715 73.0
REGS1_k127_38164_0 helicase superfamily c-terminal domain K06877 - - 3.024e-266 844.0
REGS1_k127_38164_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 425.0
REGS1_k127_38164_10 Sigma-70 region 2 K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000007046 90.0
REGS1_k127_38164_11 Domain of unknown function (DUF309) K09763 - - 0.000000000002119 78.0
REGS1_k127_38164_12 PFAM TadE family protein - - - 0.0000001463 60.0
REGS1_k127_38164_13 PFAM TadE family protein - - - 0.000001371 58.0
REGS1_k127_38164_14 Regulatory protein, FmdB family - - - 0.000001734 56.0
REGS1_k127_38164_15 Putative Flp pilus-assembly TadE/G-like K07114 - - 0.0001065 53.0
REGS1_k127_38164_2 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 388.0
REGS1_k127_38164_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 383.0
REGS1_k127_38164_4 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 302.0
REGS1_k127_38164_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000111 234.0
REGS1_k127_38164_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000001187 200.0
REGS1_k127_38164_7 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000006858 195.0
REGS1_k127_38164_8 PFAM molybdopterin binding - - - 0.00000000000000000000000000000000000000002272 165.0
REGS1_k127_38164_9 RNase_H superfamily K07502 - - 0.000000000000000000000000000000002562 146.0
REGS1_k127_3868194_0 DEAD/H associated K03724 - - 0.0 1476.0
REGS1_k127_3868194_1 Oligopeptidase F K08602 - - 8.469e-213 678.0
REGS1_k127_3868194_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 313.0
REGS1_k127_3868194_3 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000008876 242.0
REGS1_k127_3868194_4 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000001131 177.0
REGS1_k127_3868194_5 Cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000001196 129.0
REGS1_k127_3868194_6 FR47-like protein - - - 0.000000000000000000000000002314 116.0
REGS1_k127_3868194_7 - - - - 0.00000000000000000000003389 106.0
REGS1_k127_3868194_8 Phage integrase, N-terminal SAM-like domain - - - 0.00001749 48.0
REGS1_k127_3927546_0 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000001762 145.0
REGS1_k127_3927546_1 Transcriptional regulator, MarR family - - - 0.0000000000000000000000000000000002217 139.0
REGS1_k127_3927546_2 Amidohydrolase K07045 - - 0.000000000000000000000000000001574 123.0
REGS1_k127_3927546_3 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000006091 112.0
REGS1_k127_3927546_4 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000001809 109.0
REGS1_k127_3927546_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000001005 55.0
REGS1_k127_3927546_6 Transcriptional regulator - - - 0.000006976 50.0
REGS1_k127_3946067_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 288.0
REGS1_k127_3946067_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000001428 254.0
REGS1_k127_3946067_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000000000000000000000001183 194.0
REGS1_k127_3946067_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000008852 147.0
REGS1_k127_3946067_4 beta-lactamase domain protein K13075 - 3.1.1.81 0.00000000000000000000000000002798 133.0
REGS1_k127_3946067_5 Redoxin - - - 0.00000000000000000000001835 115.0
REGS1_k127_3956045_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 314.0
REGS1_k127_3956045_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000195 249.0
REGS1_k127_3956045_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000001744 71.0
REGS1_k127_399576_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 451.0
REGS1_k127_399576_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 437.0
REGS1_k127_399576_2 homoserine dehydrogenase NAD-binding K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 371.0
REGS1_k127_399576_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000001343 227.0
REGS1_k127_399576_4 Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000003857 211.0
REGS1_k127_399576_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000003651 153.0
REGS1_k127_399576_6 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000001745 140.0
REGS1_k127_399576_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000003134 122.0
REGS1_k127_399576_8 DNA-templated transcription, initiation K03088 - - 0.00000000000000002545 90.0
REGS1_k127_399580_0 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 560.0
REGS1_k127_399580_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 417.0
REGS1_k127_399580_2 tRNA synthetases class I (W and Y) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 376.0
REGS1_k127_399580_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
REGS1_k127_399580_4 RuvA, C-terminal domain K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000001506 135.0
REGS1_k127_399580_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000008373 121.0
REGS1_k127_399580_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000009899 68.0
REGS1_k127_40233_0 PAS fold-4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 446.0
REGS1_k127_40233_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.00000000000000000000000000000000000000000000000000007838 197.0
REGS1_k127_40233_2 Glycosyl transferase family group 2 K11936 - - 0.000000000000000000000000000728 132.0
REGS1_k127_40233_3 Psort location CytoplasmicMembrane, score - - - 0.000000000000000432 89.0
REGS1_k127_40233_4 Helix-turn-helix domain - - - 0.000008002 54.0
REGS1_k127_4059040_0 DEAD DEAH box helicase domain protein K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 444.0
REGS1_k127_4059040_1 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
REGS1_k127_4059040_10 Transcriptional regulator K13640 - - 0.00000000000009661 76.0
REGS1_k127_4059040_2 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008504 257.0
REGS1_k127_4059040_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008861 237.0
REGS1_k127_4059040_4 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000001011 222.0
REGS1_k127_4059040_5 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000206 223.0
REGS1_k127_4059040_6 Putative manganese efflux pump - - - 0.0000000000000000000000000000000000000000000002074 173.0
REGS1_k127_4059040_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000002611 164.0
REGS1_k127_4059040_8 - - - - 0.0000000000000000000000000000252 122.0
REGS1_k127_4059040_9 Protein conserved in bacteria K09764 - - 0.000000000000000006324 86.0
REGS1_k127_4097290_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 352.0
REGS1_k127_4097290_1 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 320.0
REGS1_k127_4097290_2 PFAM ABC transporter related K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 276.0
REGS1_k127_4097290_3 ECF transporter, substrate-specific component K16927 - - 0.000000000000000000000000000000000000000000491 168.0
REGS1_k127_4097290_4 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000006193 99.0
REGS1_k127_4097290_5 Cobalt transport protein K16785 - - 0.00000000000000000009341 103.0
REGS1_k127_4097290_6 PFAM Prenyltransferase squalene oxidase - - - 0.0000001051 61.0
REGS1_k127_4114883_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 482.0
REGS1_k127_4114883_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 359.0
REGS1_k127_4114883_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 327.0
REGS1_k127_4114883_3 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 322.0
REGS1_k127_4114883_4 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 323.0
REGS1_k127_4114883_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 304.0
REGS1_k127_4114883_6 MFS/sugar transport protein - - - 0.0000000000000002626 79.0
REGS1_k127_4114883_7 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.000002293 52.0
REGS1_k127_4243747_0 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000004528 239.0
REGS1_k127_4243747_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000002443 192.0
REGS1_k127_4321752_0 AIR synthase related protein, C-terminal domain K01952 - 6.3.5.3 1.233e-246 785.0
REGS1_k127_4321752_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 485.0
REGS1_k127_4321752_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 341.0
REGS1_k127_4321752_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 324.0
REGS1_k127_4321752_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 331.0
REGS1_k127_4321752_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000169 88.0
REGS1_k127_4321752_6 Formyl transferase K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000008338 58.0
REGS1_k127_4612123_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.476e-194 618.0
REGS1_k127_4612123_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 578.0
REGS1_k127_4612123_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060,K08322 - 1.1.1.103,1.1.1.380 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 499.0
REGS1_k127_4612123_3 PFAM ABC-3 protein K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 333.0
REGS1_k127_4612123_4 PFAM periplasmic solute binding protein K02077,K09815,K09818,K11707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 295.0
REGS1_k127_4612123_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004723 281.0
REGS1_k127_4612123_6 zinc-transporting ATPase activity K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004269 261.0
REGS1_k127_4612123_7 diguanylate cyclase - - - 0.000000000000000000000000000000003941 133.0
REGS1_k127_4612123_8 Belongs to the Fur family K03711 - - 0.00000000000004585 81.0
REGS1_k127_4612123_9 Rdx family K07401 - - 0.000000003675 60.0
REGS1_k127_4621088_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 5.856e-212 671.0
REGS1_k127_4621088_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001364 275.0
REGS1_k127_4621088_10 response regulator, receiver - - - 0.0001071 44.0
REGS1_k127_4621088_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000184 231.0
REGS1_k127_4621088_3 PFAM Hly-III family protein K11068 - - 0.000000000000000000000000000000000000000000000001643 181.0
REGS1_k127_4621088_4 Sortase family - - - 0.000000000000000009857 93.0
REGS1_k127_4621088_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000002808 64.0
REGS1_k127_4621088_6 - - - - 0.00000000027 70.0
REGS1_k127_4621088_7 Peptidoglycan-binding domain 1 protein - - - 0.0000000003446 69.0
REGS1_k127_4621088_8 Acetyltransferase (GNAT) family - - - 0.0000004555 58.0
REGS1_k127_4621088_9 FR47-like protein - - - 0.000002557 51.0
REGS1_k127_4623770_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 1.257e-249 806.0
REGS1_k127_4623770_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 514.0
REGS1_k127_4623770_10 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000001266 116.0
REGS1_k127_4623770_11 Alpha/beta hydrolase family K07020 - - 0.00000000000000000002963 97.0
REGS1_k127_4623770_12 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043142,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000007676 72.0
REGS1_k127_4623770_13 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000006902 57.0
REGS1_k127_4623770_2 Belongs to the glycosyl hydrolase 57 family K01176,K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 470.0
REGS1_k127_4623770_3 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 462.0
REGS1_k127_4623770_4 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 417.0
REGS1_k127_4623770_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004203 250.0
REGS1_k127_4623770_6 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000003619 238.0
REGS1_k127_4623770_7 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000000000004788 229.0
REGS1_k127_4623770_8 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000002318 154.0
REGS1_k127_4623770_9 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000109 126.0
REGS1_k127_4628901_0 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 450.0
REGS1_k127_4628901_1 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 319.0
REGS1_k127_4628901_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000007086 59.0
REGS1_k127_4628901_11 Evidence 4 Homologs of previously reported genes of - - - 0.0000114 47.0
REGS1_k127_4628901_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 316.0
REGS1_k127_4628901_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 304.0
REGS1_k127_4628901_4 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004442 260.0
REGS1_k127_4628901_5 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
REGS1_k127_4628901_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004204 258.0
REGS1_k127_4628901_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000001912 190.0
REGS1_k127_4628901_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000001999 109.0
REGS1_k127_4628901_9 Pfam SNARE associated Golgi protein K03975 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001113 63.0
REGS1_k127_4636790_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 482.0
REGS1_k127_4636790_1 Acyltransferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 287.0
REGS1_k127_4636790_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000207 164.0
REGS1_k127_4636790_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000001698 162.0
REGS1_k127_4636790_4 Universal stress protein - - - 0.00000000001523 70.0
REGS1_k127_4637675_0 AAA domain - - - 8.87e-263 833.0
REGS1_k127_4637675_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 3.972e-237 765.0
REGS1_k127_4637675_10 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 425.0
REGS1_k127_4637675_11 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 410.0
REGS1_k127_4637675_12 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 397.0
REGS1_k127_4637675_13 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 402.0
REGS1_k127_4637675_14 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 379.0
REGS1_k127_4637675_15 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 372.0
REGS1_k127_4637675_16 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 366.0
REGS1_k127_4637675_17 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 358.0
REGS1_k127_4637675_18 ferric reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
REGS1_k127_4637675_19 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 331.0
REGS1_k127_4637675_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 2.616e-223 719.0
REGS1_k127_4637675_20 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 322.0
REGS1_k127_4637675_21 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 312.0
REGS1_k127_4637675_22 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 300.0
REGS1_k127_4637675_23 Exporter of polyketide antibiotics K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001368 292.0
REGS1_k127_4637675_24 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 278.0
REGS1_k127_4637675_25 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
REGS1_k127_4637675_26 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002372 260.0
REGS1_k127_4637675_27 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003549 258.0
REGS1_k127_4637675_28 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001575 256.0
REGS1_k127_4637675_29 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000007884 235.0
REGS1_k127_4637675_3 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 8.183e-206 659.0
REGS1_k127_4637675_30 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000003601 233.0
REGS1_k127_4637675_31 - - - - 0.000000000000000000000000000000000000000000000000000000000001757 220.0
REGS1_k127_4637675_32 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000502 207.0
REGS1_k127_4637675_33 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
REGS1_k127_4637675_34 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000006109 194.0
REGS1_k127_4637675_35 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000968 201.0
REGS1_k127_4637675_36 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000005242 179.0
REGS1_k127_4637675_37 nodulation - - - 0.0000000000000000000000000000000000000000000002502 185.0
REGS1_k127_4637675_38 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000002772 168.0
REGS1_k127_4637675_39 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000007671 154.0
REGS1_k127_4637675_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.128e-194 622.0
REGS1_k127_4637675_40 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000006356 157.0
REGS1_k127_4637675_41 Cupin domain - - - 0.00000000000000000000000000000000000002244 151.0
REGS1_k127_4637675_42 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000004237 140.0
REGS1_k127_4637675_43 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000003769 142.0
REGS1_k127_4637675_44 - - - - 0.00000000000000000000000000000005493 141.0
REGS1_k127_4637675_45 - - - - 0.0000000000000000000000000008005 120.0
REGS1_k127_4637675_46 Alpha beta K06889 - - 0.000000000000000000000000004695 117.0
REGS1_k127_4637675_47 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000009877 108.0
REGS1_k127_4637675_48 ATP synthase subunit C K02124 - - 0.00000000000000000000000261 118.0
REGS1_k127_4637675_49 FMN-binding domain protein - - - 0.0000000000000000000000571 106.0
REGS1_k127_4637675_5 carbohydrate transport K02027,K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 602.0
REGS1_k127_4637675_50 PFAM Heat shock protein Hsp20 K13993 - - 0.000000000000000000000279 102.0
REGS1_k127_4637675_51 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000003168 92.0
REGS1_k127_4637675_52 ATP synthase subunit D K02120 - - 0.0000000000000000005468 95.0
REGS1_k127_4637675_53 PspC domain - - - 0.000000000000000001659 92.0
REGS1_k127_4637675_54 Belongs to the universal stress protein A family - - - 0.000000000000000002803 91.0
REGS1_k127_4637675_55 - - - - 0.00000000000000001659 93.0
REGS1_k127_4637675_56 AMP binding - - - 0.00000000000000005624 90.0
REGS1_k127_4637675_57 Efflux transporter, RND family, MFP subunit K02005,K13888 - - 0.0000000000000002682 93.0
REGS1_k127_4637675_58 - - - - 0.00000000001595 77.0
REGS1_k127_4637675_59 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.0000000005288 68.0
REGS1_k127_4637675_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 604.0
REGS1_k127_4637675_60 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000002118 61.0
REGS1_k127_4637675_61 Universal stress protein - - - 0.00000001427 66.0
REGS1_k127_4637675_62 PFAM TPR repeat-containing protein - - - 0.00000015 64.0
REGS1_k127_4637675_63 LURP-one-related - - - 0.00000173 57.0
REGS1_k127_4637675_64 Protein of unknown function (DUF998) - - - 0.000001785 57.0
REGS1_k127_4637675_65 Response regulator receiver - - - 0.0001415 48.0
REGS1_k127_4637675_66 hyperosmotic response K04065 - - 0.0001669 51.0
REGS1_k127_4637675_67 - - - - 0.0003244 48.0
REGS1_k127_4637675_7 Proline racemase K01777,K12658 - 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 496.0
REGS1_k127_4637675_8 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 507.0
REGS1_k127_4637675_9 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 424.0
REGS1_k127_4660856_0 hydrolase, family 65, central catalytic K05342 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.64 1.607e-269 846.0
REGS1_k127_4660856_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000001425 146.0
REGS1_k127_4660856_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000001373 139.0
REGS1_k127_4660856_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000001565 136.0
REGS1_k127_4665957_0 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 494.0
REGS1_k127_4665957_1 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 347.0
REGS1_k127_4665957_2 involved in chromosome partitioning K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000001294 239.0
REGS1_k127_4665957_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000001761 199.0
REGS1_k127_4665957_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000009057 190.0
REGS1_k127_4665957_5 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000005457 180.0
REGS1_k127_4665957_6 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000006176 152.0
REGS1_k127_4665957_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000001968 102.0
REGS1_k127_4665957_8 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000008735 89.0
REGS1_k127_4666558_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 9.48e-223 713.0
REGS1_k127_4666558_1 cellulose binding - - - 1.045e-206 651.0
REGS1_k127_4666558_2 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 340.0
REGS1_k127_4666558_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 271.0
REGS1_k127_4666558_4 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000004093 231.0
REGS1_k127_4666558_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000001469 133.0
REGS1_k127_4666558_6 Zinc-binding dehydrogenase - - - 0.0000000008662 59.0
REGS1_k127_4675692_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 506.0
REGS1_k127_4675692_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 387.0
REGS1_k127_4675692_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 325.0
REGS1_k127_4675692_3 COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
REGS1_k127_4675692_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000007509 216.0
REGS1_k127_4675692_5 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000008643 214.0
REGS1_k127_4675692_6 Uncharacterised protein family (UPF0182) K09118 - - 0.00000000000000000000000000000007857 137.0
REGS1_k127_4675692_7 Methyltransferase domain K07003 - - 0.00000000000000000000003391 109.0
REGS1_k127_4675692_8 Acetyltransferase (GNAT) domain - - - 0.000000000006835 76.0
REGS1_k127_4675692_9 DNA-binding helix-turn-helix protein - - - 0.0003508 50.0
REGS1_k127_4681906_0 amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 300.0
REGS1_k127_4681906_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
REGS1_k127_4681906_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004602 270.0
REGS1_k127_4692676_0 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 419.0
REGS1_k127_4692676_1 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000009488 220.0
REGS1_k127_4692676_2 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000003001 139.0
REGS1_k127_4692676_3 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K09471 - - 0.000000000000000001287 89.0
REGS1_k127_4699795_0 acyl-CoA dehydrogenase K09456 - - 2.357e-222 702.0
REGS1_k127_4699795_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 499.0
REGS1_k127_4699795_2 H( )-stimulated, divalent metal cation uptake system K03322 GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015077,GO:0015078,GO:0015086,GO:0015291,GO:0015292,GO:0015293,GO:0015318,GO:0015672,GO:0015684,GO:0015691,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042221,GO:0044425,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070574,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 488.0
REGS1_k127_4699795_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
REGS1_k127_4699795_4 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
REGS1_k127_4699795_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000003065 111.0
REGS1_k127_4708492_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 325.0
REGS1_k127_4708492_1 TIGRFAM stage V sporulation protein E, cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 313.0
REGS1_k127_4708492_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 309.0
REGS1_k127_4708492_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002467 288.0
REGS1_k127_4708492_4 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000002633 231.0
REGS1_k127_4708492_5 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000001126 225.0
REGS1_k127_4708492_6 small basic protein - - - 0.00000000000000000000000004191 115.0
REGS1_k127_4708492_7 POTRA domain, FtsQ-type K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000327 56.0
REGS1_k127_4725610_0 Belongs to the malate synthase family K01638 - 2.3.3.9 2.051e-249 779.0
REGS1_k127_4725610_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 395.0
REGS1_k127_4725610_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 346.0
REGS1_k127_4725610_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000001231 242.0
REGS1_k127_4725610_4 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000000000000000000008788 199.0
REGS1_k127_4725610_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000000000437 184.0
REGS1_k127_4725610_6 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000002232 69.0
REGS1_k127_4762701_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 9.218e-218 684.0
REGS1_k127_4762701_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 559.0
REGS1_k127_4762701_2 AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 558.0
REGS1_k127_4762701_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 331.0
REGS1_k127_4762701_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000497 160.0
REGS1_k127_4762701_5 FCD - - - 0.000000000000000000000001124 107.0
REGS1_k127_4767292_0 Glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 1136.0
REGS1_k127_4767292_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.073e-262 823.0
REGS1_k127_4767292_10 Purine catabolism regulatory protein-like family K09684 - - 0.000000000000000000000000000000000000000000000000000001893 212.0
REGS1_k127_4767292_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000009024 168.0
REGS1_k127_4767292_12 antisigma factor binding K04749 - - 0.00000000000000000000001961 103.0
REGS1_k127_4767292_13 response regulator, receiver - - - 0.00000000000000000000002901 108.0
REGS1_k127_4767292_14 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000004976 68.0
REGS1_k127_4767292_15 Histidine kinase - - - 0.0000006053 55.0
REGS1_k127_4767292_2 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 480.0
REGS1_k127_4767292_3 PFAM Type II IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 437.0
REGS1_k127_4767292_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001015 271.0
REGS1_k127_4767292_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
REGS1_k127_4767292_6 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
REGS1_k127_4767292_7 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000004967 232.0
REGS1_k127_4767292_8 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001995 222.0
REGS1_k127_4767292_9 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000005524 222.0
REGS1_k127_4783407_0 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
REGS1_k127_4783407_1 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 388.0
REGS1_k127_4783407_2 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000004616 83.0
REGS1_k127_4783407_3 C4-type zinc ribbon domain K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000003737 66.0
REGS1_k127_4802907_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 515.0
REGS1_k127_4802907_1 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 307.0
REGS1_k127_4802907_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002011 256.0
REGS1_k127_4802907_3 CoA-transferase family III - - - 0.00000000000000000000000000000115 125.0
REGS1_k127_4807786_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 407.0
REGS1_k127_4807786_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 360.0
REGS1_k127_4807786_10 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000003916 168.0
REGS1_k127_4807786_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000002228 156.0
REGS1_k127_4807786_12 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006491 141.0
REGS1_k127_4807786_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000001348 139.0
REGS1_k127_4807786_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000173 116.0
REGS1_k127_4807786_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000004843 113.0
REGS1_k127_4807786_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000003094 108.0
REGS1_k127_4807786_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000006317 96.0
REGS1_k127_4807786_18 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000001166 83.0
REGS1_k127_4807786_19 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000002894 71.0
REGS1_k127_4807786_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000497 260.0
REGS1_k127_4807786_20 Ribosomal protein L30 K02907 - - 0.00000001288 66.0
REGS1_k127_4807786_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008414 254.0
REGS1_k127_4807786_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000002652 222.0
REGS1_k127_4807786_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000005165 222.0
REGS1_k127_4807786_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000002716 213.0
REGS1_k127_4807786_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001967 217.0
REGS1_k127_4807786_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000008425 194.0
REGS1_k127_4807786_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000001096 172.0
REGS1_k127_4814451_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.933e-298 940.0
REGS1_k127_4814451_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 516.0
REGS1_k127_4814451_10 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000009918 146.0
REGS1_k127_4814451_11 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000004136 139.0
REGS1_k127_4814451_12 TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase K01438 - 3.5.1.16 0.000000000000002162 77.0
REGS1_k127_4814451_13 Domain of unknown function (DUF222) - - - 0.000000000005436 67.0
REGS1_k127_4814451_14 ribosomal protein S20 K02968 - - 0.0000000001218 66.0
REGS1_k127_4814451_15 exodeoxyribonuclease I activity - - - 0.000000002296 69.0
REGS1_k127_4814451_16 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0001071 53.0
REGS1_k127_4814451_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01317,K01925,K01928,K01932 - 3.4.21.10,6.3.2.13,6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 409.0
REGS1_k127_4814451_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 375.0
REGS1_k127_4814451_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 347.0
REGS1_k127_4814451_5 Class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 324.0
REGS1_k127_4814451_6 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008699 273.0
REGS1_k127_4814451_7 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
REGS1_k127_4814451_8 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000222 192.0
REGS1_k127_4814451_9 PFAM ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000009154 164.0
REGS1_k127_4817254_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
REGS1_k127_4817254_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000008858 179.0
REGS1_k127_4817254_2 PFAM response regulator receiver - - - 0.0000000000000000000000000007356 121.0
REGS1_k127_4817254_3 Histidine kinase - - - 0.00000000000000000002506 98.0
REGS1_k127_4817254_4 protein complex oligomerization - - - 0.00008388 55.0
REGS1_k127_4820746_0 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 403.0
REGS1_k127_4820746_1 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 380.0
REGS1_k127_4820746_10 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000061 138.0
REGS1_k127_4820746_11 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000003472 105.0
REGS1_k127_4820746_12 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000002716 100.0
REGS1_k127_4820746_13 - - - - 0.000000000000000001448 92.0
REGS1_k127_4820746_14 Belongs to the UPF0761 family K07058 - - 0.0000000000181 74.0
REGS1_k127_4820746_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 369.0
REGS1_k127_4820746_3 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005754 277.0
REGS1_k127_4820746_4 Predicted Zn-dependent protease (DUF2268) - - - 0.0000000000000000000000000000000000000000000000000000000000000003376 230.0
REGS1_k127_4820746_5 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000001087 218.0
REGS1_k127_4820746_6 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00000000000000000000000000000000000000000000000000000000002264 217.0
REGS1_k127_4820746_7 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.00000000000000000000000000000000000000000000000000000006848 203.0
REGS1_k127_4820746_8 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000001745 188.0
REGS1_k127_4820746_9 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000004709 150.0
REGS1_k127_4834313_0 Branched-chain amino acid aminotransferase K00826 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 514.0
REGS1_k127_4834313_1 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000655 111.0
REGS1_k127_4834313_2 PFAM Transglycosylase-associated protein - - - 0.000000000000002503 78.0
REGS1_k127_4852728_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.357e-268 835.0
REGS1_k127_4852728_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 8.636e-201 643.0
REGS1_k127_4852728_10 Belongs to the class-I aminoacyl-tRNA synthetase family K15526 - 6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 320.0
REGS1_k127_4852728_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 317.0
REGS1_k127_4852728_12 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 302.0
REGS1_k127_4852728_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 281.0
REGS1_k127_4852728_14 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004005 273.0
REGS1_k127_4852728_15 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000327 273.0
REGS1_k127_4852728_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001044 265.0
REGS1_k127_4852728_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000006557 217.0
REGS1_k127_4852728_18 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000003554 168.0
REGS1_k127_4852728_19 Membrane-associated protein - - - 0.0000000000000000000000000000000000000002859 162.0
REGS1_k127_4852728_2 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 568.0
REGS1_k127_4852728_20 deaminated base DNA N-glycosylase activity K03648,K21929 - 3.2.2.27 0.0000000000000000000000000000000000000006158 156.0
REGS1_k127_4852728_21 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000001696 152.0
REGS1_k127_4852728_22 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000001491 148.0
REGS1_k127_4852728_23 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000006853 137.0
REGS1_k127_4852728_24 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000006443 120.0
REGS1_k127_4852728_25 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.000000000000000000000000001979 114.0
REGS1_k127_4852728_26 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000004341 114.0
REGS1_k127_4852728_27 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000001208 106.0
REGS1_k127_4852728_28 YCII-related domain - - - 0.000000000000000000095 93.0
REGS1_k127_4852728_29 Domain of unknown function (DUF4349) - - - 0.000000000000000001018 97.0
REGS1_k127_4852728_3 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 544.0
REGS1_k127_4852728_30 Rieske [2Fe-2S] domain - - - 0.000000000000000001791 97.0
REGS1_k127_4852728_31 conserved protein (DUF2203) - - - 0.000000000000000003585 91.0
REGS1_k127_4852728_32 Protein of unknown function (DUF971) K03593 - - 0.000000000000000008327 92.0
REGS1_k127_4852728_33 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000002345 70.0
REGS1_k127_4852728_34 Multicopper oxidase - - - 0.000000001484 70.0
REGS1_k127_4852728_35 - - - - 0.00004328 51.0
REGS1_k127_4852728_36 Domain of unknown function (DU1801) - - - 0.0001348 45.0
REGS1_k127_4852728_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 511.0
REGS1_k127_4852728_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 362.0
REGS1_k127_4852728_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 361.0
REGS1_k127_4852728_7 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 359.0
REGS1_k127_4852728_8 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 353.0
REGS1_k127_4852728_9 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 341.0
REGS1_k127_4860425_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.12e-199 638.0
REGS1_k127_4860425_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 419.0
REGS1_k127_4860425_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000001688 243.0
REGS1_k127_4902747_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004549 263.0
REGS1_k127_4902747_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 0.000000000001518 72.0
REGS1_k127_4986480_0 PFAM Type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 452.0
REGS1_k127_4986480_1 COG4963 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.000000002801 70.0
REGS1_k127_4986480_2 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.000000008193 66.0
REGS1_k127_4986480_3 Camp-dependent protein kinase type K04739 GO:0000086,GO:0000166,GO:0000278,GO:0000902,GO:0000904,GO:0001664,GO:0001674,GO:0001932,GO:0001933,GO:0001934,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005886,GO:0005929,GO:0005952,GO:0006082,GO:0006469,GO:0006629,GO:0006631,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0007399,GO:0007409,GO:0007411,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007622,GO:0007623,GO:0007626,GO:0008150,GO:0008152,GO:0008603,GO:0009410,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010389,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010720,GO:0014070,GO:0015630,GO:0016020,GO:0016043,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019752,GO:0019866,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0022402,GO:0022406,GO:0022607,GO:0023052,GO:0030030,GO:0030031,GO:0030104,GO:0030154,GO:0030182,GO:0030234,GO:0030291,GO:0030315,GO:0030425,GO:0030534,GO:0030551,GO:0030552,GO:0030554,GO:0031090,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031625,GO:0031690,GO:0031698,GO:0031966,GO:0031967,GO:0031975,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032870,GO:0032989,GO:0032990,GO:0032991,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035556,GO:0036094,GO:0036477,GO:0040011,GO:0042060,GO:0042220,GO:0042221,GO:0042325,GO:0042326,GO:0042327,GO:0042330,GO:0042383,GO:0042493,GO:0042585,GO:0042592,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043025,GO:0043073,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043197,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043279,GO:0043434,GO:0043436,GO:0043549,GO:0043900,GO:0043902,GO:0043933,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044297,GO:0044309,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0044853,GO:0045121,GO:0045202,GO:0045471,GO:0045475,GO:0045595,GO:0045597,GO:0045787,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046677,GO:0046983,GO:0048148,GO:0048149,GO:0048468,GO:0048471,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048871,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050817,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051094,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051248,GO:0051259,GO:0051291,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051446,GO:0051640,GO:0051641,GO:0051716,GO:0051726,GO:0060255,GO:0060271,GO:0060281,GO:0060282,GO:0060284,GO:0060359,GO:0061564,GO:0061695,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072347,GO:0080090,GO:0090068,GO:0097159,GO:0097305,GO:0097332,GO:0097338,GO:0097367,GO:0097447,GO:0097458,GO:0097485,GO:0097546,GO:0097711,GO:0098589,GO:0098590,GO:0098772,GO:0098794,GO:0098805,GO:0098857,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0120039,GO:0140056,GO:1900193,GO:1900195,GO:1901265,GO:1901363,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901987,GO:1901990,GO:1902494,GO:1902749,GO:1902911,GO:1903047,GO:1903429,GO:1903431,GO:1903538,GO:1904146,GO:1905879,GO:1905881,GO:1990234,GO:2000241,GO:2000243,GO:2000479,GO:2000480 - 0.00000004563 66.0
REGS1_k127_4986480_4 Armadillo/beta-catenin-like repeats - - - 0.000002143 59.0
REGS1_k127_4986480_5 pfam rdd - - - 0.000005778 50.0
REGS1_k127_5061994_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 304.0
REGS1_k127_5061994_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 314.0
REGS1_k127_5061994_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000176 116.0
REGS1_k127_5061994_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000002572 117.0
REGS1_k127_5061994_12 Protein conserved in bacteria - - - 0.000000001566 64.0
REGS1_k127_5061994_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000003259 237.0
REGS1_k127_5061994_3 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
REGS1_k127_5061994_4 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000002955 180.0
REGS1_k127_5061994_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000003305 178.0
REGS1_k127_5061994_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000001127 171.0
REGS1_k127_5061994_7 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000000002412 151.0
REGS1_k127_5061994_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000001557 155.0
REGS1_k127_5061994_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000002573 138.0
REGS1_k127_5153724_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 391.0
REGS1_k127_5153724_1 ATPases associated with a variety of cellular activities K01995,K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 334.0
REGS1_k127_5153724_2 ATPases associated with a variety of cellular activities K01996,K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 305.0
REGS1_k127_5153724_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000003681 190.0
REGS1_k127_5153724_4 - - - - 0.000000000000000000000000335 115.0
REGS1_k127_5271776_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.177e-256 800.0
REGS1_k127_5271776_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.294e-200 645.0
REGS1_k127_5271776_2 DNA polymerase III, epsilon subunit K02342,K03722 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 591.0
REGS1_k127_5271776_3 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 309.0
REGS1_k127_5271776_4 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000001425 198.0
REGS1_k127_5271776_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000009125 203.0
REGS1_k127_5271776_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000002961 189.0
REGS1_k127_5271776_7 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000193 151.0
REGS1_k127_5271776_8 Transmembrane secretion effector - - - 0.000000000000000000000000000000003922 144.0
REGS1_k127_5321366_0 ABC transporter transmembrane region K06147 - - 9.056e-205 656.0
REGS1_k127_5321366_1 ABC transporter related K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 565.0
REGS1_k127_5321366_10 B3/4 domain K04567 - 6.1.1.6 0.00000000000000000000000001761 116.0
REGS1_k127_5321366_11 TIGRFAM MoaD family protein K03636 - - 0.00000000000000000000000006402 109.0
REGS1_k127_5321366_12 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000001633 98.0
REGS1_k127_5321366_13 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000001871 98.0
REGS1_k127_5321366_14 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000003681 85.0
REGS1_k127_5321366_15 methionine transport K02071 - - 0.0000000000000006474 81.0
REGS1_k127_5321366_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 510.0
REGS1_k127_5321366_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 478.0
REGS1_k127_5321366_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 374.0
REGS1_k127_5321366_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 327.0
REGS1_k127_5321366_6 aldo keto reductase family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 312.0
REGS1_k127_5321366_7 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000002436 180.0
REGS1_k127_5321366_8 Phosphoesterase family K21302 - 3.1.3.64 0.00000000000000000000000000000000000000000000005967 185.0
REGS1_k127_5321366_9 - - - - 0.0000000000000000000000000000000000000000000005552 172.0
REGS1_k127_5322816_0 Domain of unknown function (DUF2088) - - - 2.026e-205 651.0
REGS1_k127_5322816_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 607.0
REGS1_k127_5322816_10 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000001274 229.0
REGS1_k127_5322816_11 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000002813 217.0
REGS1_k127_5322816_12 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000001028 190.0
REGS1_k127_5322816_13 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000001574 196.0
REGS1_k127_5322816_14 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000003602 169.0
REGS1_k127_5322816_15 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000002217 128.0
REGS1_k127_5322816_16 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.000000000000000000000001775 117.0
REGS1_k127_5322816_17 CcmB protein K02194 - - 0.000000000000000000000004986 115.0
REGS1_k127_5322816_18 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000001111 103.0
REGS1_k127_5322816_19 PFAM peptidase M23B - - - 0.00000000000000000000008751 112.0
REGS1_k127_5322816_2 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 507.0
REGS1_k127_5322816_20 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000007719 102.0
REGS1_k127_5322816_21 PFAM NUDIX hydrolase - - - 0.0000000000000000006931 94.0
REGS1_k127_5322816_22 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.000000000000000007873 96.0
REGS1_k127_5322816_23 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000002984 83.0
REGS1_k127_5322816_24 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000003663 75.0
REGS1_k127_5322816_25 Mechanosensitive ion channel - - - 0.0000000000042 76.0
REGS1_k127_5322816_26 RDD family - - - 0.000000000007852 74.0
REGS1_k127_5322816_27 F420H(2)-dependent quinone reductase - - - 0.000000000009499 67.0
REGS1_k127_5322816_3 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 459.0
REGS1_k127_5322816_4 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 386.0
REGS1_k127_5322816_5 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 368.0
REGS1_k127_5322816_6 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
REGS1_k127_5322816_7 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 297.0
REGS1_k127_5322816_8 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
REGS1_k127_5322816_9 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002372 265.0
REGS1_k127_5329679_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 512.0
REGS1_k127_5329679_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 336.0
REGS1_k127_5329679_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 306.0
REGS1_k127_5329679_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000004904 251.0
REGS1_k127_5329679_4 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000004603 251.0
REGS1_k127_5329679_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000001615 235.0
REGS1_k127_5329679_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000001275 128.0
REGS1_k127_5329679_7 PucR C-terminal helix-turn-helix domain - - - 0.0000000000000004177 91.0
REGS1_k127_5329679_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.000000000009871 72.0
REGS1_k127_537620_0 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 3.167e-225 728.0
REGS1_k127_537620_1 Alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 627.0
REGS1_k127_537620_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 411.0
REGS1_k127_537620_3 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 326.0
REGS1_k127_5396335_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.481e-264 832.0
REGS1_k127_5396335_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 405.0
REGS1_k127_545770_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.278e-236 739.0
REGS1_k127_545770_1 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 441.0
REGS1_k127_545770_10 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001323 227.0
REGS1_k127_545770_11 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000002899 209.0
REGS1_k127_545770_12 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000004604 177.0
REGS1_k127_545770_13 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000001327 162.0
REGS1_k127_545770_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000002056 137.0
REGS1_k127_545770_15 phosphatidate phosphatase activity - - - 0.000000000000000000000000003952 122.0
REGS1_k127_545770_17 MMPL family K06994 - - 0.0000000001147 67.0
REGS1_k127_545770_18 Psort location CytoplasmicMembrane, score - - - 0.00001698 53.0
REGS1_k127_545770_19 Flavodoxin domain K00230 - 1.3.5.3 0.00001995 55.0
REGS1_k127_545770_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 394.0
REGS1_k127_545770_3 COG0798 Arsenite efflux pump ACR3 and related K03325,K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 397.0
REGS1_k127_545770_4 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 360.0
REGS1_k127_545770_5 MMPL family K06994,K20470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 353.0
REGS1_k127_545770_6 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 296.0
REGS1_k127_545770_7 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 300.0
REGS1_k127_545770_8 Transport permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000001006 234.0
REGS1_k127_545770_9 Adenosine/AMP deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000009984 233.0
REGS1_k127_55768_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.829e-221 701.0
REGS1_k127_55768_1 Peptidase family M3 K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 608.0
REGS1_k127_55768_10 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003569 253.0
REGS1_k127_55768_11 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000004602 255.0
REGS1_k127_55768_12 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000009137 185.0
REGS1_k127_55768_13 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000003426 175.0
REGS1_k127_55768_14 alpha beta - - - 0.00000000000000000000000000000000000000000000106 175.0
REGS1_k127_55768_15 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000008681 164.0
REGS1_k127_55768_16 acetyltransferase - - - 0.00000000000000000000000000000000001618 151.0
REGS1_k127_55768_17 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000003583 153.0
REGS1_k127_55768_18 carbon monoxide dehydrogenase subunit G - - - 0.00000000000000000000000000000001371 134.0
REGS1_k127_55768_19 EamA-like transporter family - - - 0.0000000000000000000000000000009268 133.0
REGS1_k127_55768_2 the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 538.0
REGS1_k127_55768_20 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000003005 122.0
REGS1_k127_55768_21 - - - - 0.00000000000000000000002374 111.0
REGS1_k127_55768_22 PFAM Methyltransferase type 11 - - - 0.0000000000000000000009341 108.0
REGS1_k127_55768_23 Bacterial regulatory proteins, tetR family - - - 0.000000000000001473 85.0
REGS1_k127_55768_24 Cold shock K03704 - - 0.0000000000003154 74.0
REGS1_k127_55768_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 412.0
REGS1_k127_55768_4 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 409.0
REGS1_k127_55768_5 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 350.0
REGS1_k127_55768_6 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 334.0
REGS1_k127_55768_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002665 286.0
REGS1_k127_55768_8 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001775 277.0
REGS1_k127_55768_9 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 252.0
REGS1_k127_559927_0 exo-alpha-(2->6)-sialidase activity - - - 6.125e-209 666.0
REGS1_k127_559927_1 High-affinity nickel-transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 484.0
REGS1_k127_559927_2 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 368.0
REGS1_k127_559927_3 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003676 275.0
REGS1_k127_559927_4 - - - - 0.0000000000000000009891 98.0
REGS1_k127_559927_5 - - - - 0.00000000005928 70.0
REGS1_k127_559927_6 Bacterial regulatory proteins, tetR family - - - 0.00000001642 58.0
REGS1_k127_559927_7 CAAX protease self-immunity - - - 0.000004092 58.0
REGS1_k127_559927_8 5-oxoprolinase (ATP-hydrolyzing) activity - - - 0.0003837 51.0
REGS1_k127_5602487_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.12e-241 756.0
REGS1_k127_5602487_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 622.0
REGS1_k127_5602487_2 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 340.0
REGS1_k127_5602487_3 Predicted membrane protein (DUF2079) - - - 0.000000001424 70.0
REGS1_k127_5685963_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003765 273.0
REGS1_k127_5685963_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000001565 255.0
REGS1_k127_5685963_2 PFAM O-methyltransferase, family 3 - - - 0.00000000000000000000000000000000000008814 149.0
REGS1_k127_5786149_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 578.0
REGS1_k127_5786149_1 COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 546.0
REGS1_k127_5786149_10 Cache domain - - - 0.00000000000000000000000000002798 133.0
REGS1_k127_5786149_11 Beta-lactamase superfamily domain - - - 0.00000000000000000000001139 112.0
REGS1_k127_5786149_12 - - - - 0.00000000000000000001161 96.0
REGS1_k127_5786149_13 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000002069 100.0
REGS1_k127_5786149_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 446.0
REGS1_k127_5786149_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 381.0
REGS1_k127_5786149_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000002132 255.0
REGS1_k127_5786149_5 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001221 236.0
REGS1_k127_5786149_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000001224 209.0
REGS1_k127_5786149_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000001475 203.0
REGS1_k127_5786149_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000357 192.0
REGS1_k127_5786149_9 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000004289 170.0
REGS1_k127_5818005_0 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 332.0
REGS1_k127_5818005_1 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
REGS1_k127_5832524_0 Drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 594.0
REGS1_k127_5832524_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000006533 221.0
REGS1_k127_5832524_2 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000001088 145.0
REGS1_k127_5832524_3 peptidase activity - - - 0.00000000000000000000000002382 123.0
REGS1_k127_5832524_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000002634 53.0
REGS1_k127_5843032_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 429.0
REGS1_k127_5843032_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 364.0
REGS1_k127_5843032_10 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000005276 182.0
REGS1_k127_5843032_11 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000002593 174.0
REGS1_k127_5843032_12 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000003228 108.0
REGS1_k127_5843032_13 - - - - 0.00000005823 60.0
REGS1_k127_5843032_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 312.0
REGS1_k127_5843032_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007617 266.0
REGS1_k127_5843032_4 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
REGS1_k127_5843032_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
REGS1_k127_5843032_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000003573 254.0
REGS1_k127_5843032_7 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
REGS1_k127_5843032_8 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000001186 228.0
REGS1_k127_5843032_9 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000007601 227.0
REGS1_k127_5847241_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 - - 7.466e-248 782.0
REGS1_k127_5847241_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.994e-208 678.0
REGS1_k127_5847241_10 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000002059 242.0
REGS1_k127_5847241_11 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008144,GO:0008150,GO:0008559,GO:0015238,GO:0015399,GO:0015405,GO:0015893,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902495,GO:1990195,GO:1990196,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000002728 253.0
REGS1_k127_5847241_12 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000001205 228.0
REGS1_k127_5847241_13 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000006241 218.0
REGS1_k127_5847241_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000004249 195.0
REGS1_k127_5847241_15 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000006674 166.0
REGS1_k127_5847241_16 MgtC family K07507 - - 0.00000000000000000000000000000000005208 139.0
REGS1_k127_5847241_17 CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.00000000000000000000001592 103.0
REGS1_k127_5847241_18 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000003277 105.0
REGS1_k127_5847241_19 Hydroxysteroid dehydrogenase like 2 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000008093 90.0
REGS1_k127_5847241_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.867e-202 639.0
REGS1_k127_5847241_20 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000008945 88.0
REGS1_k127_5847241_21 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000001292 83.0
REGS1_k127_5847241_22 hydrolase (HAD superfamily) K07025 - - 0.000000000002469 76.0
REGS1_k127_5847241_23 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000003659 72.0
REGS1_k127_5847241_24 CsbD-like - - - 0.000000006336 59.0
REGS1_k127_5847241_3 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 526.0
REGS1_k127_5847241_4 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 467.0
REGS1_k127_5847241_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 429.0
REGS1_k127_5847241_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 358.0
REGS1_k127_5847241_7 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 346.0
REGS1_k127_5847241_8 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 295.0
REGS1_k127_5847241_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004799 255.0
REGS1_k127_5853279_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 3.403e-198 628.0
REGS1_k127_5853279_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 527.0
REGS1_k127_5853279_2 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 507.0
REGS1_k127_5853279_3 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 413.0
REGS1_k127_5853279_4 ABC transporter (Permease K02054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 361.0
REGS1_k127_5853279_5 ABC transporter (permease) K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 324.0
REGS1_k127_5853279_6 oxidoreductase - - - 0.0000000000000000000000000000000083 136.0
REGS1_k127_5884021_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 465.0
REGS1_k127_5900088_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 522.0
REGS1_k127_5900088_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000186 231.0
REGS1_k127_5900088_2 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000006665 225.0
REGS1_k127_5900088_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07171 - - 0.0000000000000000000000000000000004418 133.0
REGS1_k127_5905533_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 522.0
REGS1_k127_5905533_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 302.0
REGS1_k127_5905533_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000001787 207.0
REGS1_k127_5905533_3 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000005117 192.0
REGS1_k127_5905533_4 EVE domain - - - 0.00000000000000000000000000000000000000000000000008845 183.0
REGS1_k127_5905533_5 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000005348 186.0
REGS1_k127_5905533_6 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms - - - 0.0000000000000000000000000000000000000000000008858 171.0
REGS1_k127_5905533_7 Sigma-70 region 2 K03088 - - 0.000000000000005789 82.0
REGS1_k127_5905533_8 Belongs to the metal hydrolase YfiT family - - - 0.0001383 51.0
REGS1_k127_5941224_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 597.0
REGS1_k127_5941224_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 518.0
REGS1_k127_5941224_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000218 295.0
REGS1_k127_5941224_11 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 269.0
REGS1_k127_5941224_12 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009113 254.0
REGS1_k127_5941224_13 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000005 251.0
REGS1_k127_5941224_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000006169 241.0
REGS1_k127_5941224_15 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000002476 208.0
REGS1_k127_5941224_16 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000006208 171.0
REGS1_k127_5941224_17 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000002029 147.0
REGS1_k127_5941224_18 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000969 140.0
REGS1_k127_5941224_19 Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase K07001 - - 0.00000000000000000000000000000000007783 149.0
REGS1_k127_5941224_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 515.0
REGS1_k127_5941224_20 Branched-chain amino acid transport system / permease component K01997 - - 0.000005682 48.0
REGS1_k127_5941224_3 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 503.0
REGS1_k127_5941224_4 UDP binding domain K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 436.0
REGS1_k127_5941224_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 426.0
REGS1_k127_5941224_6 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 412.0
REGS1_k127_5941224_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 411.0
REGS1_k127_5941224_8 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 308.0
REGS1_k127_5941224_9 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
REGS1_k127_5941335_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 353.0
REGS1_k127_5941335_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000001956 156.0
REGS1_k127_5941335_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000001161 116.0
REGS1_k127_5941335_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000002151 82.0
REGS1_k127_5967753_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.259e-265 837.0
REGS1_k127_5967753_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 456.0
REGS1_k127_5967753_10 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000006708 174.0
REGS1_k127_5967753_11 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000001098 112.0
REGS1_k127_5967753_12 TspO/MBR family K05770 - - 0.00000000000000000000002391 106.0
REGS1_k127_5967753_13 Metallo-beta-lactamase superfamily - - - 0.000000000000000000001301 101.0
REGS1_k127_5967753_14 PFAM Transglycosylase-associated protein - - - 0.000000000000001012 79.0
REGS1_k127_5967753_15 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000139 81.0
REGS1_k127_5967753_16 Pfam:DUF1049 - - - 0.0000000000001511 74.0
REGS1_k127_5967753_17 Protein of unknown function (DUF4242) - - - 0.000000000001341 68.0
REGS1_k127_5967753_18 Glycosyltransferase family 87 K16647 GO:0008150,GO:0040007 2.4.2.47 0.00000000313 69.0
REGS1_k127_5967753_19 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000001733 59.0
REGS1_k127_5967753_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 360.0
REGS1_k127_5967753_3 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 330.0
REGS1_k127_5967753_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 314.0
REGS1_k127_5967753_5 Coenzyme F420 hydrogenase dehydrogenase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 310.0
REGS1_k127_5967753_6 transferase activity, transferring glycosyl groups K20885 - 2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 308.0
REGS1_k127_5967753_7 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001393 299.0
REGS1_k127_5967753_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005461 254.0
REGS1_k127_5967753_9 Highly conserved protein containing a thioredoxin domain K02027 - - 0.00000000000000000000000000000000000000000000001502 186.0
REGS1_k127_5971047_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 1.214e-295 930.0
REGS1_k127_5971047_1 PFAM Type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 462.0
REGS1_k127_5971047_10 Peptidase M23 K21471 - - 0.0000000000000000000000000000000007298 145.0
REGS1_k127_5971047_11 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000002575 94.0
REGS1_k127_5971047_12 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000005568 59.0
REGS1_k127_5971047_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 370.0
REGS1_k127_5971047_3 ABC transporter K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001671 286.0
REGS1_k127_5971047_4 PFAM type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000001995 229.0
REGS1_k127_5971047_5 PFAM alpha beta hydrolase fold K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000001671 208.0
REGS1_k127_5971047_6 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000002081 212.0
REGS1_k127_5971047_7 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000001327 162.0
REGS1_k127_5971047_8 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000000000001029 153.0
REGS1_k127_5971047_9 competence protein - - - 0.000000000000000000000000000000000002389 146.0
REGS1_k127_6007901_0 mannose metabolic process K01191 - 3.2.1.24 2.459e-208 667.0
REGS1_k127_6007901_1 AzlC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001207 239.0
REGS1_k127_6007901_2 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000009552 156.0
REGS1_k127_6007901_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000001177 151.0
REGS1_k127_6007901_4 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000001424 103.0
REGS1_k127_6019719_0 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001462 279.0
REGS1_k127_6019719_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000002073 247.0
REGS1_k127_6019719_2 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000005533 131.0
REGS1_k127_6019719_3 Winged helix-turn helix - - - 0.00000000000000000000000000003355 123.0
REGS1_k127_6019719_4 DDE superfamily endonuclease - - - 0.0000000000000000000000000005866 119.0
REGS1_k127_6019719_5 Cupin domain - - - 0.0000000000001565 72.0
REGS1_k127_6041934_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 371.0
REGS1_k127_6041934_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 350.0
REGS1_k127_6041934_2 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 278.0
REGS1_k127_6068200_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.024e-238 743.0
REGS1_k127_6068200_1 KR domain - - - 2.326e-208 670.0
REGS1_k127_6068200_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 563.0
REGS1_k127_6068200_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004871 257.0
REGS1_k127_6068200_4 phosphorelay signal transduction system K07667 - - 0.000000000000000000000000000000000000000000000000000000000000003895 229.0
REGS1_k127_6068200_5 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000008292 216.0
REGS1_k127_6068200_6 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000004016 131.0
REGS1_k127_6068200_7 Amino acid permease K03294 - - 0.0000000000000000000000000002019 125.0
REGS1_k127_6068200_8 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000001896 106.0
REGS1_k127_6068200_9 protein kinase activity - - - 0.000000008022 64.0
REGS1_k127_6068586_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003415 254.0
REGS1_k127_6068586_1 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000002787 229.0
REGS1_k127_6068586_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000007108 187.0
REGS1_k127_6068586_3 ABC transporter - - - 0.0000000000000000000000001195 108.0
REGS1_k127_6090400_0 TIGRFAM DNA binding domain - - - 0.000000000000000000002076 101.0
REGS1_k127_6090400_1 Carboxymuconolactone decarboxylase family K14727 - 3.1.1.24,4.1.1.44 0.00000000001198 64.0
REGS1_k127_6090400_2 OsmC-like protein - - - 0.000004706 51.0
REGS1_k127_6090400_3 - - - - 0.00005019 55.0
REGS1_k127_6161700_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 357.0
REGS1_k127_6161700_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000002088 210.0
REGS1_k127_6161700_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000003701 157.0
REGS1_k127_6161700_3 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000001016 121.0
REGS1_k127_6161700_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000001219 64.0
REGS1_k127_6193744_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 594.0
REGS1_k127_6193744_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 387.0
REGS1_k127_6193744_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000001459 147.0
REGS1_k127_6193744_11 ATPase or kinase K06925 GO:0008150,GO:0040007 - 0.00000000000000000000001459 106.0
REGS1_k127_6193744_12 Putative zinc-finger - - - 0.0000000000002662 72.0
REGS1_k127_6193744_13 YbbR-like protein - - - 0.00000000002752 74.0
REGS1_k127_6193744_14 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000002317 70.0
REGS1_k127_6193744_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000004652 61.0
REGS1_k127_6193744_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 317.0
REGS1_k127_6193744_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 299.0
REGS1_k127_6193744_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002958 266.0
REGS1_k127_6193744_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000009736 233.0
REGS1_k127_6193744_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000004602 226.0
REGS1_k127_6193744_7 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000469 162.0
REGS1_k127_6193744_8 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000002597 154.0
REGS1_k127_6193744_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000001757 146.0
REGS1_k127_6221502_0 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002211 271.0
REGS1_k127_6221502_1 peptidase S1 and S6, chymotrypsin Hap K08372 - - 0.00000000000000000000000000000000000000000000000000007146 205.0
REGS1_k127_6221502_2 transglycosylase - - - 0.00000000000000000000000000002397 128.0
REGS1_k127_6221502_3 transcriptional - - - 0.00000000000000006976 83.0
REGS1_k127_6221502_4 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000006298 84.0
REGS1_k127_6221502_5 Transcriptional regulatory protein, C terminal K07666 - - 0.000000000001049 78.0
REGS1_k127_6221502_6 Family of unknown function (DUF5317) - - - 0.00001512 55.0
REGS1_k127_6222914_0 FAD binding domain K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 455.0
REGS1_k127_6222914_1 protocatechuate 3,4-dioxygenase, beta subunit' K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 343.0
REGS1_k127_6222914_2 Carboxymuconolactone decarboxylase family K01607,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000001053 172.0
REGS1_k127_6222914_3 Dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000003305 162.0
REGS1_k127_6222914_4 Periplasmic binding protein K01999 - - 0.0000000009636 63.0
REGS1_k127_6229729_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.949e-197 623.0
REGS1_k127_6229729_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 523.0
REGS1_k127_6229729_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 294.0
REGS1_k127_6229729_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 299.0
REGS1_k127_6229729_12 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001253 286.0
REGS1_k127_6229729_13 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
REGS1_k127_6229729_14 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000001288 220.0
REGS1_k127_6229729_15 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000003495 199.0
REGS1_k127_6229729_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000183 191.0
REGS1_k127_6229729_17 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000004813 173.0
REGS1_k127_6229729_18 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000009526 164.0
REGS1_k127_6229729_19 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000002964 143.0
REGS1_k127_6229729_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 499.0
REGS1_k127_6229729_20 TPR repeat - - - 0.000000000000000000000000000000001211 141.0
REGS1_k127_6229729_21 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000004081 136.0
REGS1_k127_6229729_22 Membrane K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000001325 107.0
REGS1_k127_6229729_23 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000002236 92.0
REGS1_k127_6229729_24 Uncharacterized conserved protein (DUF2277) - - - 0.000000000001063 71.0
REGS1_k127_6229729_25 - - - - 0.00004097 53.0
REGS1_k127_6229729_3 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 475.0
REGS1_k127_6229729_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 429.0
REGS1_k127_6229729_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 419.0
REGS1_k127_6229729_6 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 396.0
REGS1_k127_6229729_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 360.0
REGS1_k127_6229729_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 363.0
REGS1_k127_6229729_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 325.0
REGS1_k127_6280800_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 368.0
REGS1_k127_6280800_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 334.0
REGS1_k127_6280800_2 PFAM regulatory protein, MarR - - - 0.00002046 53.0
REGS1_k127_6329454_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001155 250.0
REGS1_k127_6329454_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000002723 160.0
REGS1_k127_6329454_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000001224 160.0
REGS1_k127_6329454_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000157 129.0
REGS1_k127_6431502_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01848 - 5.4.99.2 4.41e-227 717.0
REGS1_k127_6431502_1 PFAM carboxyl transferase - - - 4.099e-221 698.0
REGS1_k127_6431502_10 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 276.0
REGS1_k127_6431502_11 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000533 216.0
REGS1_k127_6431502_12 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000006316 195.0
REGS1_k127_6431502_13 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000005307 156.0
REGS1_k127_6431502_14 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000001007 151.0
REGS1_k127_6431502_15 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000005325 151.0
REGS1_k127_6431502_16 sterol carrier protein - - - 0.00000000000000000000001509 105.0
REGS1_k127_6431502_17 Protein of unknown function (DUF4013) - - - 0.000000001355 67.0
REGS1_k127_6431502_18 Protein of unknown function (DUF2752) - - - 0.0000006633 59.0
REGS1_k127_6431502_19 Domain of unknown function (DUF4190) - - - 0.000125 50.0
REGS1_k127_6431502_2 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 7.318e-214 679.0
REGS1_k127_6431502_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 518.0
REGS1_k127_6431502_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 428.0
REGS1_k127_6431502_5 Acyl-CoA dehydrogenase, C-terminal domain K00248,K18244 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 373.0
REGS1_k127_6431502_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 353.0
REGS1_k127_6431502_7 succinate-CoA ligase activity K01903 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 355.0
REGS1_k127_6431502_8 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 315.0
REGS1_k127_6431502_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005432 281.0
REGS1_k127_6590094_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000002458 109.0
REGS1_k127_6590094_1 Exporter of polyketide K01992 - - 0.00000000000566 79.0
REGS1_k127_6590094_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000001376 66.0
REGS1_k127_659160_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 535.0
REGS1_k127_659160_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 336.0
REGS1_k127_6620761_0 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 554.0
REGS1_k127_6620761_1 PAS fold - - - 0.0000000000000000000000118 109.0
REGS1_k127_6620761_2 - - - - 0.00000004236 59.0
REGS1_k127_6841627_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.353e-247 787.0
REGS1_k127_6841627_1 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 454.0
REGS1_k127_6841627_10 PBS lyase HEAT-like repeat - - - 0.0001507 54.0
REGS1_k127_6841627_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 302.0
REGS1_k127_6841627_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000002643 235.0
REGS1_k127_6841627_4 domain protein - - - 0.000000000000000000000000000000000000000396 157.0
REGS1_k127_6841627_5 Type II secretion system K12511 - - 0.0000000000000000000000000000001798 135.0
REGS1_k127_6841627_6 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000006407 130.0
REGS1_k127_6841627_7 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000792 72.0
REGS1_k127_6841627_8 AAA domain K02282 - - 0.00000003384 66.0
REGS1_k127_6841627_9 PFAM TadE family protein - - - 0.00007285 51.0
REGS1_k127_684433_0 Belongs to the ClpA ClpB family K03695,K03696 - - 1.969e-320 1000.0
REGS1_k127_684433_1 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 512.0
REGS1_k127_684433_10 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008919 241.0
REGS1_k127_684433_11 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
REGS1_k127_684433_12 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000003929 216.0
REGS1_k127_684433_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000003117 199.0
REGS1_k127_684433_14 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000124 204.0
REGS1_k127_684433_15 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000004234 189.0
REGS1_k127_684433_16 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000001103 172.0
REGS1_k127_684433_17 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000002555 150.0
REGS1_k127_684433_18 PFAM RDD domain containing protein - - - 0.0000000000000000000000000000000006705 140.0
REGS1_k127_684433_19 YacP-like NYN domain K06962 - - 0.0000000000000000000000003139 114.0
REGS1_k127_684433_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 448.0
REGS1_k127_684433_20 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000001054 86.0
REGS1_k127_684433_21 pathogenesis K02417,K02519 - - 0.00000000000000002972 92.0
REGS1_k127_684433_22 Transcriptional regulatory protein, C terminal K02483 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771 - 0.0000000000003049 72.0
REGS1_k127_684433_23 - - - - 0.00000000006684 71.0
REGS1_k127_684433_24 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000001718 59.0
REGS1_k127_684433_25 Domain of unknown function (DUF4350) - - - 0.000008288 59.0
REGS1_k127_684433_26 Domain of unknown function (DUF4129) - - - 0.0003792 53.0
REGS1_k127_684433_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 447.0
REGS1_k127_684433_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 418.0
REGS1_k127_684433_5 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 367.0
REGS1_k127_684433_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 318.0
REGS1_k127_684433_7 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 306.0
REGS1_k127_684433_8 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 263.0
REGS1_k127_684433_9 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004012 259.0
REGS1_k127_6949013_0 Methionine synthase K00548 - 2.1.1.13 0.0 1554.0
REGS1_k127_6949770_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 259.0
REGS1_k127_6949770_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000001492 213.0
REGS1_k127_6949770_2 PFAM Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000002687 114.0
REGS1_k127_6949770_3 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.0000000009285 67.0
REGS1_k127_6949770_4 PFAM PKD domain containing protein - - - 0.00007976 50.0
REGS1_k127_6953742_0 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 345.0
REGS1_k127_6953742_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 316.0
REGS1_k127_6953742_2 Mur ligase middle domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005836 286.0
REGS1_k127_6953742_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 0.000000000000000000000000000000000000000000000000000001389 205.0
REGS1_k127_6953742_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000004701 103.0
REGS1_k127_6953742_5 oligopeptidase that cleaves peptide bonds following arginine and lysine residues K01354 - 3.4.21.83 0.00000001487 56.0
REGS1_k127_6958906_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 408.0
REGS1_k127_6958906_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 308.0
REGS1_k127_6958906_2 polysaccharide catabolic process K05991 - 3.2.1.123 0.0000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
REGS1_k127_6958906_3 PucR C-terminal helix-turn-helix domain - - - 0.000000000000000000000000000000000000000001627 177.0
REGS1_k127_6958906_4 ATPases associated with a variety of cellular activities K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000001093 153.0
REGS1_k127_6958906_5 Peptidase, M23 K21471 - - 0.000000000000000000000000001732 128.0
REGS1_k127_6958906_6 ApbE family K03734 - 2.7.1.180 0.0000000000000000006558 88.0
REGS1_k127_6976007_0 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
REGS1_k127_6976007_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003844 242.0
REGS1_k127_6976007_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000002153 181.0
REGS1_k127_6976007_11 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000008065 172.0
REGS1_k127_6976007_12 TIGRFAM molybdenum cofactor synthesis domain K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000005881 166.0
REGS1_k127_6976007_13 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000001215 135.0
REGS1_k127_6976007_14 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000005025 134.0
REGS1_k127_6976007_15 AraC-like ligand binding domain - - - 0.0000000000000000000001105 99.0
REGS1_k127_6976007_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000002841 74.0
REGS1_k127_6976007_17 Protein of unknown function (DUF1706) - - - 0.00000000006247 71.0
REGS1_k127_6976007_18 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000003911 72.0
REGS1_k127_6976007_19 Redoxin K03564 - 1.11.1.15 0.00004626 46.0
REGS1_k127_6976007_2 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000001199 233.0
REGS1_k127_6976007_3 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000001356 219.0
REGS1_k127_6976007_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001212 230.0
REGS1_k127_6976007_5 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000002376 235.0
REGS1_k127_6976007_6 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000002418 220.0
REGS1_k127_6976007_7 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000008271 205.0
REGS1_k127_6976007_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000007276 183.0
REGS1_k127_6976007_9 5-oxoprolinase (ATP-hydrolyzing) activity K01457,K06351,K07160 - 3.5.1.54 0.0000000000000000000000000000000000000000000000001047 184.0
REGS1_k127_6985380_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 506.0
REGS1_k127_6985380_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 306.0
REGS1_k127_6985380_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000001604 169.0
REGS1_k127_6985380_3 MaoC like domain - - - 0.0000000000000000002697 92.0
REGS1_k127_6985380_4 N-terminal half of MaoC dehydratase - - - 0.0000000006073 68.0
REGS1_k127_6997631_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 505.0
REGS1_k127_6997631_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 422.0
REGS1_k127_6997631_10 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000005324 217.0
REGS1_k127_6997631_11 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000005113 209.0
REGS1_k127_6997631_12 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B - - - 0.00000000000000000000000000000000000000000000000000001309 199.0
REGS1_k127_6997631_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000002629 198.0
REGS1_k127_6997631_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000009397 190.0
REGS1_k127_6997631_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000003598 172.0
REGS1_k127_6997631_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000005307 156.0
REGS1_k127_6997631_17 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000004364 133.0
REGS1_k127_6997631_18 SPTR D1C1B9 DinB family protein - - - 0.00000000000000000000000000009757 121.0
REGS1_k127_6997631_19 Ribosomal protein S16 K02959 - - 0.0000000000000000000000000003156 121.0
REGS1_k127_6997631_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 350.0
REGS1_k127_6997631_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000001143 115.0
REGS1_k127_6997631_21 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000001415 121.0
REGS1_k127_6997631_22 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000005559 117.0
REGS1_k127_6997631_23 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000396 106.0
REGS1_k127_6997631_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000009783 91.0
REGS1_k127_6997631_25 Belongs to the UPF0102 family K07460 - - 0.000000000000000001174 93.0
REGS1_k127_6997631_26 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein K09787 - - 0.00000000000005626 76.0
REGS1_k127_6997631_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000001195 79.0
REGS1_k127_6997631_28 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000009996 70.0
REGS1_k127_6997631_29 KH domain K06960 - - 0.0000000004792 65.0
REGS1_k127_6997631_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 304.0
REGS1_k127_6997631_30 Putative ATP-binding cassette K01992 - - 0.000002023 61.0
REGS1_k127_6997631_31 Exporter of polyketide K01992 - - 0.000002629 60.0
REGS1_k127_6997631_4 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 303.0
REGS1_k127_6997631_5 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 254.0
REGS1_k127_6997631_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002013 249.0
REGS1_k127_6997631_7 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000008368 244.0
REGS1_k127_6997631_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000009013 243.0
REGS1_k127_6997631_9 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000002507 231.0
REGS1_k127_7013474_0 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 348.0
REGS1_k127_7013474_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
REGS1_k127_7013474_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001488 281.0
REGS1_k127_7013474_3 Domain of unknown function (DUF929) - - - 0.0000000000000000000000000000000000000000000000000000000000009963 221.0
REGS1_k127_7013474_4 COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000000000000000000003497 198.0
REGS1_k127_7013474_5 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000001955 189.0
REGS1_k127_7013474_6 quinone binding - - - 0.000000000000000000000000000000001597 134.0
REGS1_k127_7013474_7 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000193 133.0
REGS1_k127_7013474_8 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.0000292 51.0
REGS1_k127_7019656_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 3.594e-206 651.0
REGS1_k127_7019656_1 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 418.0
REGS1_k127_7019656_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 368.0
REGS1_k127_7019656_3 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000003547 229.0
REGS1_k127_7019656_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000003524 135.0
REGS1_k127_7019656_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000001762 121.0
REGS1_k127_7019656_6 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.000000000000002288 78.0
REGS1_k127_7028190_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 610.0
REGS1_k127_7028190_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 503.0
REGS1_k127_7028190_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 503.0
REGS1_k127_7028190_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649,K02594,K09011 - 2.3.1.182,2.3.3.13,2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 421.0
REGS1_k127_7028190_4 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 383.0
REGS1_k127_7028190_5 Dehydrogenase E1 component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001219 296.0
REGS1_k127_7028190_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000954 191.0
REGS1_k127_708966_0 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000002388 260.0
REGS1_k127_708966_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000003782 214.0
REGS1_k127_708966_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000001235 154.0
REGS1_k127_7098623_0 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
REGS1_k127_7098623_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000003707 220.0
REGS1_k127_7098623_2 FR47-like protein - - - 0.000000000000000000000000000000000000002273 158.0
REGS1_k127_7098623_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000004019 151.0
REGS1_k127_7098623_4 Thioesterase superfamily - - - 0.0000001142 59.0
REGS1_k127_7122030_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000001321 167.0
REGS1_k127_7122030_1 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000004853 128.0
REGS1_k127_7142624_0 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000001184 161.0
REGS1_k127_7142624_1 Transposase DDE domain group 1 - - - 0.000000000000000000005887 106.0
REGS1_k127_7142624_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000002575 94.0
REGS1_k127_7142624_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000003819 91.0
REGS1_k127_7142624_4 Belongs to the ompA family - - - 0.0000000000000007774 85.0
REGS1_k127_7146560_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 384.0
REGS1_k127_7146560_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 346.0
REGS1_k127_7146560_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
REGS1_k127_7146560_3 BON domain - - - 0.0000000000000000000000000000000000000000001726 168.0
REGS1_k127_7146560_4 OsmC-like protein - - - 0.0000000000000000000000002071 108.0
REGS1_k127_7146560_5 - - - - 0.000000007191 64.0
REGS1_k127_7146560_6 Universal stress protein - - - 0.000000727 61.0
REGS1_k127_7181736_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.092e-257 806.0
REGS1_k127_7181736_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 380.0
REGS1_k127_7181736_2 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 372.0
REGS1_k127_7181736_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 366.0
REGS1_k127_7181736_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000003101 235.0
REGS1_k127_7181736_5 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000002285 193.0
REGS1_k127_7181736_6 DNA recombination K09760 - - 0.0000000000000000000000000000000000000002712 165.0
REGS1_k127_7181736_7 metal ion binding K13355 - - 0.0000000000000000000000000000005501 133.0
REGS1_k127_7181736_8 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000306 104.0
REGS1_k127_7185237_0 Heat shock 70 kDa protein K04043 - - 5.795e-267 835.0
REGS1_k127_7185237_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.51e-229 729.0
REGS1_k127_7185237_10 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000002534 218.0
REGS1_k127_7185237_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000001971 203.0
REGS1_k127_7185237_12 ATP synthase A chain - - - 0.000000000000000000000000000000000000000000001926 179.0
REGS1_k127_7185237_13 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000003428 153.0
REGS1_k127_7185237_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000001956 149.0
REGS1_k127_7185237_15 Peptidase M50 - - - 0.000000000000000000000000000000000002013 149.0
REGS1_k127_7185237_16 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain K08372 - - 0.000000000000000000000000000000000004217 150.0
REGS1_k127_7185237_17 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000006212 120.0
REGS1_k127_7185237_18 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001037 116.0
REGS1_k127_7185237_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000099 99.0
REGS1_k127_7185237_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.672e-210 669.0
REGS1_k127_7185237_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0015988,GO:0015991,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000002533 89.0
REGS1_k127_7185237_21 Glycosyltransferase family 87 - - - 0.00000000000002392 85.0
REGS1_k127_7185237_22 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000001271 63.0
REGS1_k127_7185237_24 PFAM GCN5-related N-acetyltransferase - - - 0.00006845 52.0
REGS1_k127_7185237_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 513.0
REGS1_k127_7185237_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 400.0
REGS1_k127_7185237_5 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 407.0
REGS1_k127_7185237_6 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000004831 231.0
REGS1_k127_7185237_7 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000009665 226.0
REGS1_k127_7185237_8 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000471 224.0
REGS1_k127_7185237_9 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000807 218.0
REGS1_k127_7200036_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 610.0
REGS1_k127_7200036_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 547.0
REGS1_k127_7200036_10 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
REGS1_k127_7200036_11 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
REGS1_k127_7200036_12 Bacterial capsule synthesis protein PGA_cap K07282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002567 194.0
REGS1_k127_7200036_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000001648 188.0
REGS1_k127_7200036_14 Belongs to the peptidase S11 family K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.000000000000000000000000000000000001786 152.0
REGS1_k127_7200036_15 Mov34 MPN PAD-1 - - - 0.0000000000000000000000004303 115.0
REGS1_k127_7200036_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 427.0
REGS1_k127_7200036_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 418.0
REGS1_k127_7200036_4 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 417.0
REGS1_k127_7200036_5 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 407.0
REGS1_k127_7200036_6 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 379.0
REGS1_k127_7200036_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 362.0
REGS1_k127_7200036_8 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 329.0
REGS1_k127_7200036_9 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 310.0
REGS1_k127_7242576_0 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 330.0
REGS1_k127_7242576_1 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000002788 236.0
REGS1_k127_7242576_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000001089 81.0
REGS1_k127_7250821_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 324.0
REGS1_k127_7250821_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 258.0
REGS1_k127_7250821_2 Electron transport protein K03887 - - 0.00000000000000000000000000000000000000000000000000000000000001231 228.0
REGS1_k127_7250821_3 Polysaccharide biosynthesis protein - - - 0.00000000000000000001221 106.0
REGS1_k127_7250821_4 PFAM Exonuclease RNase T and DNA polymerase III K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.000000000000000000924 101.0
REGS1_k127_7250821_5 FAD dependent oxidoreductase - - - 0.000000000000007939 81.0
REGS1_k127_7250821_6 Cytochrome Cbb3 K03888 - - 0.000000006276 66.0
REGS1_k127_7264259_0 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 472.0
REGS1_k127_7264259_1 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008304 274.0
REGS1_k127_7264259_2 ABC transporter K01996 - - 0.00000000000000006043 89.0
REGS1_k127_7423858_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.205e-211 685.0
REGS1_k127_7423858_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 480.0
REGS1_k127_7423858_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 396.0
REGS1_k127_7423858_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 290.0
REGS1_k127_7423858_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000003336 217.0
REGS1_k127_7425956_0 exo-alpha-(2->6)-sialidase activity - - - 2.505e-212 679.0
REGS1_k127_7425956_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 610.0
REGS1_k127_7425956_10 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000007637 131.0
REGS1_k127_7425956_2 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007576 420.0
REGS1_k127_7425956_3 COGs COG0747 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 422.0
REGS1_k127_7425956_4 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 355.0
REGS1_k127_7425956_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 350.0
REGS1_k127_7425956_6 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000005251 263.0
REGS1_k127_7425956_7 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004435 260.0
REGS1_k127_7425956_8 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000008582 148.0
REGS1_k127_7425956_9 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000001822 136.0
REGS1_k127_7440620_0 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 505.0
REGS1_k127_7440620_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 368.0
REGS1_k127_7440620_10 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000001968 106.0
REGS1_k127_7440620_11 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000007567 94.0
REGS1_k127_7440620_2 beta-mannosidase K01192 - 3.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000004004 258.0
REGS1_k127_7440620_3 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000002653 236.0
REGS1_k127_7440620_4 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000002773 197.0
REGS1_k127_7440620_5 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000001225 178.0
REGS1_k127_7440620_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000535 171.0
REGS1_k127_7440620_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000001608 171.0
REGS1_k127_7440620_8 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000006172 152.0
REGS1_k127_7440620_9 acetyltransferase - - - 0.000000000000000000007101 105.0
REGS1_k127_7492293_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 3.058e-283 897.0
REGS1_k127_7492293_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.063e-222 701.0
REGS1_k127_7492293_2 Aldehyde dehydrogenase family K00135,K08324 GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 551.0
REGS1_k127_7492293_3 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000004237 223.0
REGS1_k127_7492293_4 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000001629 170.0
REGS1_k127_7492293_5 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000001869 96.0
REGS1_k127_7492293_6 CYTH domain K01768,K05873 - 4.6.1.1 0.0000000000000003354 86.0
REGS1_k127_7495224_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 293.0
REGS1_k127_7495224_1 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001474 276.0
REGS1_k127_7495224_2 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002014 274.0
REGS1_k127_7495224_3 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000005403 241.0
REGS1_k127_7495224_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000006646 213.0
REGS1_k127_7495224_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000005449 175.0
REGS1_k127_7495224_6 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000004047 184.0
REGS1_k127_7543906_0 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 458.0
REGS1_k127_7543906_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000005897 230.0
REGS1_k127_7543906_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000003091 204.0
REGS1_k127_7543906_3 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000007088 184.0
REGS1_k127_7543906_4 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000005136 139.0
REGS1_k127_7543906_5 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000002959 109.0
REGS1_k127_7543906_6 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000005013 81.0
REGS1_k127_7543906_7 Flp Fap pilin component K02651 - - 0.000001351 52.0
REGS1_k127_7621229_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 400.0
REGS1_k127_7621229_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000382 229.0
REGS1_k127_7621229_2 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000001053 208.0
REGS1_k127_7621229_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000003345 190.0
REGS1_k127_7621229_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000005099 171.0
REGS1_k127_7621229_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000008942 155.0
REGS1_k127_7621229_6 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.000000000000000197 86.0
REGS1_k127_7621229_7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000007111 81.0
REGS1_k127_7662485_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 466.0
REGS1_k127_7662485_1 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 357.0
REGS1_k127_7662485_2 tRNA processing K06864,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 294.0
REGS1_k127_7662485_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000008787 160.0
REGS1_k127_7840475_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.691e-255 803.0
REGS1_k127_7840475_1 PFAM amine oxidase K00274 - 1.4.3.4 2.72e-200 638.0
REGS1_k127_7840475_2 Major facilitator superfamily K03449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004683 273.0
REGS1_k127_7915523_0 Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 315.0
REGS1_k127_7915523_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 310.0
REGS1_k127_7915523_2 - - - - 0.0000000000000000000000000000000000000000000001311 180.0
REGS1_k127_7915523_3 - - - - 0.0000000000000000000000000000000000000001353 154.0
REGS1_k127_7915523_4 - - - - 0.00000000000000000000000006093 110.0
REGS1_k127_7915523_5 - - - - 0.0000000000000001644 84.0
REGS1_k127_8024412_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 473.0
REGS1_k127_8024412_1 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001987 248.0
REGS1_k127_8082339_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.673e-249 796.0
REGS1_k127_8082339_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 575.0
REGS1_k127_8082339_10 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000003412 57.0
REGS1_k127_8082339_11 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05559,K05565 - - 0.00002338 57.0
REGS1_k127_8082339_12 3-oxoacyl-(Acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.0006441 47.0
REGS1_k127_8082339_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 416.0
REGS1_k127_8082339_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 336.0
REGS1_k127_8082339_4 Clp protease K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
REGS1_k127_8082339_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003953 264.0
REGS1_k127_8082339_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000007177 235.0
REGS1_k127_8082339_7 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000004123 113.0
REGS1_k127_8082339_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000005747 79.0
REGS1_k127_8082339_9 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - 0.0000007538 59.0
REGS1_k127_8114600_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.265e-249 812.0
REGS1_k127_8114600_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 344.0
REGS1_k127_8114600_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000002182 238.0
REGS1_k127_8114600_3 MazG nucleotide pyrophosphohydrolase domain K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000001274 229.0
REGS1_k127_8114600_4 Peptidyl-tRNA hydrolase K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000002263 168.0
REGS1_k127_8114600_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000002478 179.0
REGS1_k127_8114600_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000002932 148.0
REGS1_k127_8114600_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000000000001757 97.0
REGS1_k127_8114600_8 Male sterility protein K12454 - 5.1.3.10 0.00000000000000001047 88.0
REGS1_k127_8114600_9 - - - - 0.0000000000004906 74.0
REGS1_k127_8186063_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 481.0
REGS1_k127_8186063_1 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 380.0
REGS1_k127_8186063_2 F420H(2)-dependent quinone reductase - - - 0.000000000074 65.0
REGS1_k127_8201649_0 Amino acid permease - - - 8.334e-215 678.0
REGS1_k127_8201649_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 496.0
REGS1_k127_8201649_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 349.0
REGS1_k127_8201649_3 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000002699 227.0
REGS1_k127_8201649_4 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K07010 - - 0.000000000000000000000000000000000000000002774 165.0
REGS1_k127_8201649_5 Secreted repeat of unknown function - - - 0.000000000000000000001088 99.0
REGS1_k127_8225836_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.425e-272 856.0
REGS1_k127_8225836_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 584.0
REGS1_k127_8225836_10 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003874 288.0
REGS1_k127_8225836_11 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005012 273.0
REGS1_k127_8225836_12 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001317 271.0
REGS1_k127_8225836_13 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000001519 250.0
REGS1_k127_8225836_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000006255 238.0
REGS1_k127_8225836_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000006574 223.0
REGS1_k127_8225836_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000007424 229.0
REGS1_k127_8225836_17 domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000003758 219.0
REGS1_k127_8225836_18 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000005378 213.0
REGS1_k127_8225836_19 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000121 210.0
REGS1_k127_8225836_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 575.0
REGS1_k127_8225836_20 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000001145 199.0
REGS1_k127_8225836_21 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000002259 196.0
REGS1_k127_8225836_22 Stage V sporulation protein S (SpoVS) K06416 - - 0.00000000000000000000000000000001504 129.0
REGS1_k127_8225836_23 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000002634 127.0
REGS1_k127_8225836_24 Ribosome-binding factor A K02834 - - 0.0000000000000000000000000000008387 129.0
REGS1_k127_8225836_25 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.00000000000000000000000000001216 134.0
REGS1_k127_8225836_26 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000617 101.0
REGS1_k127_8225836_27 Domain of unknown function (DUF4115) - - - 0.000000000000000003322 93.0
REGS1_k127_8225836_28 BNR/Asp-box repeat - - - 0.0000000000000006547 83.0
REGS1_k127_8225836_29 Protein of unknown function (DUF448) K07742 - - 0.000000000000549 76.0
REGS1_k127_8225836_3 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 556.0
REGS1_k127_8225836_30 Modulates RecA activity K03565 - - 0.0000000000009782 75.0
REGS1_k127_8225836_4 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 527.0
REGS1_k127_8225836_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 479.0
REGS1_k127_8225836_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 381.0
REGS1_k127_8225836_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
REGS1_k127_8225836_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 303.0
REGS1_k127_8225836_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 291.0
REGS1_k127_8242803_0 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 565.0
REGS1_k127_8242803_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 466.0
REGS1_k127_8242803_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000008908 92.0
REGS1_k127_8249687_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 484.0
REGS1_k127_8249687_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 345.0
REGS1_k127_8249687_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000001759 224.0
REGS1_k127_8249687_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000261 53.0
REGS1_k127_8270961_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1010.0
REGS1_k127_8270961_1 Beta-glucosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 515.0
REGS1_k127_8270961_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 493.0
REGS1_k127_8270961_3 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 342.0
REGS1_k127_8270961_4 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000002571 214.0
REGS1_k127_8270961_5 Maltogenic Amylase, C-terminal domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000008315 207.0
REGS1_k127_8270961_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000004713 184.0
REGS1_k127_8411379_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 7.193e-245 769.0
REGS1_k127_8411379_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 301.0
REGS1_k127_8411379_2 KDPG and KHG aldolase - - - 0.0000000000000000000000000000000002993 140.0
REGS1_k127_8411379_3 Flp Fap pilin component K02651 - - 0.0001344 46.0
REGS1_k127_8411379_4 Flp Fap pilin component K02651 - - 0.0004207 45.0
REGS1_k127_8414017_0 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 347.0
REGS1_k127_8414017_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 331.0
REGS1_k127_8414017_10 beta-lactamase domain protein K13075 - 3.1.1.81 0.00000000000000000000000000000003061 143.0
REGS1_k127_8414017_11 Redoxin - - - 0.000000000000000000007532 106.0
REGS1_k127_8414017_12 N-terminal half of MaoC dehydratase - - - 0.0000000000000009697 87.0
REGS1_k127_8414017_13 zinc-ribbon domain - - - 0.000002814 55.0
REGS1_k127_8414017_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
REGS1_k127_8414017_3 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 290.0
REGS1_k127_8414017_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000002086 262.0
REGS1_k127_8414017_5 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000000000002708 148.0
REGS1_k127_8414017_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000001206 147.0
REGS1_k127_8414017_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000009795 136.0
REGS1_k127_8414017_8 - - - - 0.000000000000000000000000000000008363 140.0
REGS1_k127_8414017_9 MaoC like domain - - - 0.00000000000000000000000000000001231 139.0
REGS1_k127_8436488_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 1.479e-238 754.0
REGS1_k127_8436488_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 466.0
REGS1_k127_8436488_10 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000004382 173.0
REGS1_k127_8436488_11 arginine transmembrane transporter activity - - - 0.00000000000000000000000000000000000000009281 158.0
REGS1_k127_8436488_12 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000002331 162.0
REGS1_k127_8436488_13 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000002979 151.0
REGS1_k127_8436488_14 Dodecin K09165 - - 0.000000000000000000000002466 104.0
REGS1_k127_8436488_15 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000737 100.0
REGS1_k127_8436488_16 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000008634 77.0
REGS1_k127_8436488_17 pfam cbs - - - 0.000000000005528 68.0
REGS1_k127_8436488_18 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000001039 63.0
REGS1_k127_8436488_19 PFAM FecR protein - - - 0.00000002806 66.0
REGS1_k127_8436488_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 316.0
REGS1_k127_8436488_20 PFAM FecR protein - - - 0.00000146 61.0
REGS1_k127_8436488_3 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
REGS1_k127_8436488_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005886 256.0
REGS1_k127_8436488_5 Psort location CytoplasmicMembrane, score K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000397 227.0
REGS1_k127_8436488_6 peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000203 202.0
REGS1_k127_8436488_7 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000002383 191.0
REGS1_k127_8436488_8 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000001566 182.0
REGS1_k127_8436488_9 Cbs domain - - - 0.0000000000000000000000000000000000000000000003716 179.0
REGS1_k127_8516038_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 582.0
REGS1_k127_8516038_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 290.0
REGS1_k127_8516038_10 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000005096 119.0
REGS1_k127_8516038_11 PFAM Transglycosylase-associated protein - - - 0.00000000000000000009109 93.0
REGS1_k127_8516038_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000001656 91.0
REGS1_k127_8516038_13 Putative esterase - - - 0.00000000000000004481 92.0
REGS1_k127_8516038_14 PFAM PspC domain K03973 - - 0.00000000005155 66.0
REGS1_k127_8516038_15 Dimerisation domain - - - 0.000000003694 61.0
REGS1_k127_8516038_16 2-phosphosulpholactate phosphatase - - - 0.000000578 54.0
REGS1_k127_8516038_17 Cupin 2, conserved barrel domain protein - - - 0.000005305 53.0
REGS1_k127_8516038_18 Diguanylate cyclase - - - 0.000006796 55.0
REGS1_k127_8516038_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001532 280.0
REGS1_k127_8516038_3 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 280.0
REGS1_k127_8516038_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000008743 264.0
REGS1_k127_8516038_5 Type IV secretory pathway, VirB4 - - - 0.000000000000000000000000000000000000000000000000000000002616 224.0
REGS1_k127_8516038_6 acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000002031 213.0
REGS1_k127_8516038_7 Phosphoglycerate mutase family K02226 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 0.00000000000000000000000000000000000000000000001675 185.0
REGS1_k127_8516038_8 Hydrolase, alpha beta domain protein K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000001915 181.0
REGS1_k127_8516038_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000004011 166.0
REGS1_k127_8548130_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 545.0
REGS1_k127_8548130_1 formate dehydrogenase, beta subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 437.0
REGS1_k127_8548130_2 CoA-transferase family III K14470 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016853,GO:0016866,GO:0016867,GO:0043427,GO:0071704 5.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 419.0
REGS1_k127_8548130_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 341.0
REGS1_k127_8548130_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
REGS1_k127_8548130_5 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 284.0
REGS1_k127_8548130_6 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000001403 263.0
REGS1_k127_8548130_7 Aldolase/RraA K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000009146 246.0
REGS1_k127_8548130_8 ferric iron binding K02380 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000001364 222.0
REGS1_k127_8548130_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000004221 94.0
REGS1_k127_8556995_0 - - - - 0.000000000000000000000000000000000000000000000000000000001799 208.0
REGS1_k127_8556995_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000006217 169.0
REGS1_k127_8556995_2 Uncharacterised protein, DegV family COG1307 - - - 0.00003186 46.0
REGS1_k127_8562591_0 Dehydrogenase E1 component K00615 - 2.2.1.1 5.389e-301 942.0
REGS1_k127_8562591_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 549.0
REGS1_k127_8562591_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 320.0
REGS1_k127_8562591_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 325.0
REGS1_k127_8562591_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 307.0
REGS1_k127_8562591_5 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000001139 75.0
REGS1_k127_8579308_0 PFAM type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000001754 183.0
REGS1_k127_8579308_1 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000001791 168.0
REGS1_k127_8579308_2 PFAM MerR family regulatory protein K13640 - - 0.0000000000007236 71.0
REGS1_k127_8579308_3 PFAM TadE family protein - - - 0.0000002374 61.0
REGS1_k127_8579308_4 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000749 60.0
REGS1_k127_8579308_5 Putative Flp pilus-assembly TadE/G-like - - - 0.000001545 57.0
REGS1_k127_8579308_6 TadE-like protein - - - 0.00005419 53.0
REGS1_k127_870196_0 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000001068 192.0
REGS1_k127_870196_1 membrane - - - 0.0000000000000000000004992 105.0
REGS1_k127_870196_2 Protein of unknown function, DUF393 - - - 0.00008658 49.0
REGS1_k127_870196_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.000316 44.0
REGS1_k127_8745306_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 325.0
REGS1_k127_8745306_1 PFAM binding-protein-dependent transport systems inner membrane component K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002083 268.0
REGS1_k127_8745306_2 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000007182 226.0
REGS1_k127_8745306_3 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.00000000000000000000000000000000000000000000001155 181.0
REGS1_k127_8745306_4 DNA binding domain - - - 0.0000000000000000000000000000000000005836 147.0
REGS1_k127_8828_0 Binding-protein-dependent transport system inner membrane component K02033 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 331.0
REGS1_k127_8828_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000002652 230.0
REGS1_k127_8828_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000009223 151.0
REGS1_k127_8828_3 Luciferase-like monooxygenase - - - 0.000001627 52.0
REGS1_k127_91370_0 PFAM Sodium calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 295.0
REGS1_k127_91370_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001919 223.0
REGS1_k127_91370_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000001069 199.0