GWM

Global Wetland Microbiome Database

Overview

Taxonomy
ID	MAG03306
Name	REGS1_bin.40
Sample	SMP0079 102.611633.112
Kingdom	Bacteria
Phylum	Acidobacteriota
Class	Vicinamibacteria
Order	Vicinamibacterales
Family	JAHECP01
Genus	JAHECP01
Species
Assembly information
Completeness (%)	72.54
Contamination (%)	0.23
GC content (%)	70.0
N50 (bp)	18,481
Genome size (bp)	2,648,153

Location

Module

Module ID	Module name	Total genes	Total steps	Contain genes	Contain steps	Percentage of genes	Percentage of steps

Genes2115

Gene name	Description	KEGG	GOs	EC	E-value	Score
REGS1_k127_1028714_0	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	K06978	-	-	2.108e-319	995.0
REGS1_k127_1028714_1	Gamma-glutamyltranspeptidase	K00681	-	2.3.2.2,3.4.19.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641	600.0
REGS1_k127_1028714_2	PFAM aldo keto reductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065	460.0
REGS1_k127_1028714_3	Beta-lactamase enzyme family	K17836	-	3.5.2.6	0.00000000000000000000000000000000000000000000000000000000000000000000000187	258.0
REGS1_k127_1028714_4	transcriptional regulator	K05501	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	0.000000000000000000000000000000000000001387	154.0
REGS1_k127_1044854_0	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	K03388,K12527	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237	565.0
REGS1_k127_1044854_1	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223	460.0
REGS1_k127_1044854_2	Cytochrome c	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001238	293.0
REGS1_k127_1044854_3	Polysaccharide lyase family 4, domain II	-	-	-	0.00000000000000000000000000000000000009464	155.0
REGS1_k127_1044854_4	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	0.0000000000000000000000000000001027	140.0
REGS1_k127_1044854_5	Rieske [2Fe-2S] domain	K02636	-	1.10.9.1	0.0000000000000000000005617	112.0
REGS1_k127_1044854_6	Glucose / Sorbosone dehydrogenase	-	-	-	0.0000000001845	72.0
REGS1_k127_1044854_7	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	0.0005617	48.0
REGS1_k127_1063016_0	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	K03702	-	-	6.764e-290	904.0
REGS1_k127_1063016_1	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	K01667,K01668	-	4.1.99.1,4.1.99.2	2.452e-198	627.0
REGS1_k127_1063016_10	Belongs to the purine pyrimidine phosphoribosyltransferase family	K00760	-	2.4.2.8	0.0000000000000000000000000000000000000000000000000000000003262	207.0
REGS1_k127_1063016_11	PAS domain	-	-	-	0.000000000000000000000000000000000000000000000000000002825	194.0
REGS1_k127_1063016_12	galactose-6-phosphate isomerase activity	K00761,K01808	-	2.4.2.9,5.3.1.6	0.00000000000000000000000000000000003263	143.0
REGS1_k127_1063016_13	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	0.00000000000000000000001354	112.0
REGS1_k127_1063016_14	PFAM Mammalian cell entry related domain protein	K02067	-	-	0.0000000000000000000006143	108.0
REGS1_k127_1063016_15	YtxH-like protein	-	-	-	0.0000008305	54.0
REGS1_k127_1063016_2	Amidohydrolase family	K12960	-	3.5.4.28,3.5.4.31	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017	455.0
REGS1_k127_1063016_3	Cys/Met metabolism PLP-dependent enzyme	K01739,K01760,K01761	-	2.5.1.48,4.4.1.11,4.4.1.8	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132	377.0
REGS1_k127_1063016_4	Mechanosensitive ion channel	K22044	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769	310.0
REGS1_k127_1063016_5	PFAM phosphoesterase, RecJ domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000008464	281.0
REGS1_k127_1063016_6	Belongs to the MlaE permease family	K02066	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000005954	256.0
REGS1_k127_1063016_7	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	K01619	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	0.0000000000000000000000000000000000000000000000000000000000000000000002598	259.0
REGS1_k127_1063016_8	ABC transporter	K02065	-	-	0.000000000000000000000000000000000000000000000000000000000000000000003379	244.0
REGS1_k127_1063016_9	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	K00761	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	0.000000000000000000000000000000000000000000000000000000000006767	214.0
REGS1_k127_115185_0	Pyridoxal-dependent decarboxylase conserved domain	K01593,K01634	-	4.1.1.105,4.1.1.28,4.1.2.27	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329	577.0
REGS1_k127_115185_1	Belongs to the argininosuccinate synthase family. Type 1 subfamily	K01940	-	6.3.4.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678	523.0
REGS1_k127_115185_2	TIGRFAM argininosuccinate lyase	K01755	-	4.3.2.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928	421.0
REGS1_k127_115185_3	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	K00145	-	1.2.1.38	0.0000000000000000000000000000000000000000000000000000007242	201.0
REGS1_k127_115185_4	Regulates arginine biosynthesis genes	K03402	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	0.0000000000000000000000005274	112.0
REGS1_k127_115185_5	BON domain	-	-	-	0.000000000002583	78.0
REGS1_k127_115185_6	Putative phosphatase (DUF442)	-	-	-	0.0006535	49.0
REGS1_k127_1161009_0	ABC transporter C-terminal domain	K06158	-	-	9.718e-202	648.0
REGS1_k127_1161009_1	Bacterial capsule synthesis protein PGA_cap	K07282	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273	508.0
REGS1_k127_1161009_10	Domain of unknown function DUF11	-	-	-	0.0000000006887	73.0
REGS1_k127_1161009_2	Beta-lactamase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242	472.0
REGS1_k127_1161009_3	Bacterial regulatory protein, Fis family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339	442.0
REGS1_k127_1161009_4	PFAM ATP-binding region, ATPase domain protein	K02668,K07708,K07709	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000003453	213.0
REGS1_k127_1161009_5	histidine kinase A domain protein	K02482	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000002895	213.0
REGS1_k127_1161009_6	two component, sigma54 specific, transcriptional regulator, Fis family	K07714	-	-	0.000000000000000000000003817	109.0
REGS1_k127_1161009_7	TonB-dependent receptor	-	-	-	0.0000000000000000000002094	104.0
REGS1_k127_1161009_8	Chaperone	-	-	-	0.0000000000000000000296	102.0
REGS1_k127_1161009_9	Helix-turn-helix domain	-	-	-	0.0000000003163	63.0
REGS1_k127_117605_0	Proton-conducting membrane transporter	K12137,K15828	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363	586.0
REGS1_k127_117605_1	NADH dehydrogenase (ubiquinone) activity	K14089	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459	525.0
REGS1_k127_117605_10	PFAM Thioredoxin	K03671	-	-	0.000000000000000000000000000000000000967	149.0
REGS1_k127_117605_11	ArsR family transcriptional regulator	-	-	-	0.000000000000000000000000000000388	125.0
REGS1_k127_117605_12	Formylmethanofuran dehydrogenase, subunit e	K11261	-	1.2.7.12	0.00000000000000000000000000002927	119.0
REGS1_k127_117605_13	Scp-like extracellular	-	-	-	0.00000000000000000000000008203	115.0
REGS1_k127_117605_14	cell redox homeostasis	-	-	-	0.000000000000003534	80.0
REGS1_k127_117605_15	TIGRFAM redox-active disulfide protein 2	-	-	-	0.00000000000001659	74.0
REGS1_k127_117605_16	-	-	-	-	0.000000653	53.0
REGS1_k127_117605_2	Proton-conducting membrane transporter	K12141	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324	383.0
REGS1_k127_117605_3	electron transfer activity	K00428	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.11.1.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783	317.0
REGS1_k127_117605_4	SMART Elongator protein 3 MiaB NifB	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182	310.0
REGS1_k127_117605_5	NADH dehydrogenase	K00337	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112	321.0
REGS1_k127_117605_6	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000003464	239.0
REGS1_k127_117605_7	PFAM cytochrome c biogenesis protein, transmembrane region	K06196	-	-	0.0000000000000000000000000000000000000000000000000000000000000422	225.0
REGS1_k127_117605_8	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	-	-	-	0.000000000000000000000000000000000000000000001831	179.0
REGS1_k127_117605_9	Hydrogenase 4 membrane	K12140	GO:0008150,GO:0040007	-	0.0000000000000000000000000000000000001455	149.0
REGS1_k127_1228350_0	lipopolysaccharide transport	K22110	-	-	0.0	1430.0
REGS1_k127_1228350_1	Heat shock 70 kDa protein	K04043	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501	527.0
REGS1_k127_1228350_10	LAO AO transport system ATPase	K07588	-	-	0.0000000000001612	73.0
REGS1_k127_1228350_2	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219	474.0
REGS1_k127_1228350_3	Heat shock 70 kDa protein	K04043	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123	414.0
REGS1_k127_1228350_4	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485	301.0
REGS1_k127_1228350_5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	K03686	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672	301.0
REGS1_k127_1228350_6	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	K03086	-	-	0.00000000000000000000000000000000000000000000000000000000004129	215.0
REGS1_k127_1228350_7	IstB-like ATP binding protein	K02315	-	-	0.00000000000000000000000000000000000000000000000000000005576	207.0
REGS1_k127_1228350_8	domain, Protein	-	-	-	0.00000000000000000000000000000000000000000000000005136	199.0
REGS1_k127_1228350_9	Transcriptional regulator, MerR family	K13640	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	0.0000000000000000000000000000000000000000003643	162.0
REGS1_k127_1229266_0	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	K00962	-	2.7.7.8	5.813e-263	831.0
REGS1_k127_1229266_1	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	K02519	-	-	7.886e-235	743.0
REGS1_k127_1229266_10	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	K02956	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.00000000000000000000000000000000004398	135.0
REGS1_k127_1229266_11	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	K02834	-	-	0.0000000000000000000000000009809	119.0
REGS1_k127_1229266_12	Uncharacterized ACR, COG1430	K09005	-	-	0.000000000000000001088	102.0
REGS1_k127_1229266_13	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	K03116	-	-	0.0000000000000008669	83.0
REGS1_k127_1229266_14	Cupredoxin-like domain	K00376	-	1.7.2.4	0.0000004448	58.0
REGS1_k127_1229266_2	TonB-dependent receptor	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852	544.0
REGS1_k127_1229266_3	Belongs to the peptidase S41A family	K03797	-	3.4.21.102	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838	383.0
REGS1_k127_1229266_4	Required for chromosome condensation and partitioning	K03529	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999	401.0
REGS1_k127_1229266_5	PFAM peptidase M48 Ste24p	K06013	-	3.4.24.84	0.00000000000000000000000000000000000000000000000000000000000000000000003141	255.0
REGS1_k127_1229266_6	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	K03118	-	-	0.0000000000000000000000000000000000000000000000000000000000000000004124	237.0
REGS1_k127_1229266_7	DHH family	K06881	-	3.1.13.3,3.1.3.7	0.00000000000000000000000000000000000000000000000000000000000000371	233.0
REGS1_k127_1229266_8	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	K03177	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	0.00000000000000000000000000000000000000000000000000000000000001458	230.0
REGS1_k127_1229266_9	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	K03118	-	-	0.0000000000000000000000000000000000000000000000003307	186.0
REGS1_k127_1241921_0	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	K00656,K20038	-	2.3.1.54,4.3.99.4	0.0	1154.0
REGS1_k127_1241921_1	L-lactate permease	K03303	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853	596.0
REGS1_k127_1241921_10	-	-	-	-	0.00000000000000000000000000004341	134.0
REGS1_k127_1241921_11	LUD domain	K00782,K18929	-	-	0.000000000000000000000496	104.0
REGS1_k127_1241921_12	-	-	-	-	0.000000000000000002762	98.0
REGS1_k127_1241921_13	SnoaL-like domain	-	-	-	0.000000000002735	73.0
REGS1_k127_1241921_14	phosphorelay sensor kinase activity	K02660,K03406,K07675,K11525,K17763	-	2.7.13.3	0.000000005027	64.0
REGS1_k127_1241921_2	Peptidase dimerisation domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525	578.0
REGS1_k127_1241921_3	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	K00820	-	2.6.1.16	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758	564.0
REGS1_k127_1241921_4	TIGRFAM iron-sulfur cluster binding protein	K18929	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196	456.0
REGS1_k127_1241921_5	proline dipeptidase activity	K01262	-	3.4.11.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958	396.0
REGS1_k127_1241921_6	NADPH:quinone reductase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403	368.0
REGS1_k127_1241921_7	glycyl-radical enzyme activating protein family	K04069	-	1.97.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705	307.0
REGS1_k127_1241921_8	Cysteine-rich domain	K18928	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000007888	267.0
REGS1_k127_1241921_9	O-methyltransferase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000846	254.0
REGS1_k127_1251097_0	Sortilin, neurotensin receptor 3,	-	-	-	0.0	1295.0
REGS1_k127_1251097_1	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	K03296	-	-	2.775e-246	795.0
REGS1_k127_1251097_2	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000002096	231.0
REGS1_k127_1251097_3	Cold shock protein domain	-	-	-	0.000000000000000002741	86.0
REGS1_k127_1251097_4	OmpA family	K03286	-	-	0.0000000003696	65.0
REGS1_k127_1251097_5	-	-	-	-	0.00001567	57.0
REGS1_k127_1252966_0	Belongs to the amidase family	K02433	-	6.3.5.6,6.3.5.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889	367.0
REGS1_k127_1252966_1	ABC transporter, ATP-binding protein	K02049,K15555,K15600	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541	312.0
REGS1_k127_1252966_2	Alpha/beta hydrolase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000001595	238.0
REGS1_k127_1252966_3	Binding-protein-dependent transport system inner membrane component	K02050	-	-	0.000000000000000000000000000000000000000000000000000000000001048	221.0
REGS1_k127_1252966_4	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	K03417	-	4.1.3.30	0.000000000000000000000000000000000000000003183	160.0
REGS1_k127_1252966_5	NMT1-like family	K02051	-	-	0.00000000000000000000000000000001002	146.0
REGS1_k127_1252966_6	C-C_Bond_Lyase of the TIM-Barrel fold	K01644	-	4.1.3.34	0.00000000000000000000002875	110.0
REGS1_k127_1260943_0	Sigma-54 interaction domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826	501.0
REGS1_k127_1260943_1	Multi-sensor signal transduction histidine kinase	K07710	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963	312.0
REGS1_k127_1260943_2	BON domain	-	-	-	0.0000000000792	72.0
REGS1_k127_1303024_0	PFAM LmbE family protein	K22136	-	-	1.274e-288	911.0
REGS1_k127_1303024_1	Argininosuccinate lyase C-terminal	K01755	-	4.3.2.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677	445.0
REGS1_k127_1303024_2	Bacillithiol biosynthesis BshC	K22136	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266	336.0
REGS1_k127_1303024_3	Protein kinase domain	K12132	-	2.7.11.1	0.000000000000000000004813	108.0
REGS1_k127_1306766_0	cellulose binding	-	-	-	0.0	1338.0
REGS1_k127_1306766_1	DEAD DEAH box helicase	K03654	-	3.6.4.12	1.139e-198	638.0
REGS1_k127_1306766_10	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	K19746	-	1.4.99.6	0.000000000000000000000000000000000001765	162.0
REGS1_k127_1306766_11	DinB superfamily	-	-	-	0.00000000000000000000000000000000001723	155.0
REGS1_k127_1306766_12	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	0.0000001016	63.0
REGS1_k127_1306766_13	virulence factor family protein	-	-	-	0.00001537	56.0
REGS1_k127_1306766_2	efflux transmembrane transporter activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283	564.0
REGS1_k127_1306766_3	Amino acid kinase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858	526.0
REGS1_k127_1306766_4	Penicillin amidase	K01434,K07116	-	3.5.1.11,3.5.1.97	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499	509.0
REGS1_k127_1306766_5	two component, sigma54 specific, transcriptional regulator, Fis family	K02481,K07713	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144	386.0
REGS1_k127_1306766_6	Serine threonine protein kinase	K12132	-	2.7.11.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237	368.0
REGS1_k127_1306766_7	Belongs to the short-chain dehydrogenases reductases (SDR) family	K07124	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098	305.0
REGS1_k127_1306766_8	ferroxidase activity	K03594	GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771	1.16.3.1	0.0000000000000000000000000000000000000000000000000000000000000001962	224.0
REGS1_k127_1306766_9	DinB superfamily	K07552	-	-	0.000000000000000000000000000000000000000000000000000005305	194.0
REGS1_k127_13073_0	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	K03168	-	5.99.1.2	6.4e-283	891.0
REGS1_k127_13073_1	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	K04094	-	2.1.1.74	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824	519.0
REGS1_k127_13073_11	Acetyltransferase (GNAT) domain	-	-	-	0.0000000000364	71.0
REGS1_k127_13073_2	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	K03979	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882	384.0
REGS1_k127_13073_3	Phage integrase, N-terminal SAM-like domain	K03733,K04763	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000005262	269.0
REGS1_k127_13073_4	TIGRFAM DNA protecting protein DprA	K04096	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000006998	260.0
REGS1_k127_13073_5	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	0.0000000000000000000000000000000000000000000000000000008592	204.0
REGS1_k127_13073_6	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	K00969	-	2.7.7.18	0.000000000000000000000000000000000007492	154.0
REGS1_k127_13073_7	Belongs to the bacterial ribosomal protein bL27 family	K02899	-	-	0.000000000000000000000000000006658	121.0
REGS1_k127_13073_8	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	K09710	-	-	0.0000000000000000000000000000788	122.0
REGS1_k127_13073_9	This protein binds to 23S rRNA in the presence of protein L20	K02888	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000001048	100.0
REGS1_k127_1315647_0	cellulose binding	-	-	-	0.0	1351.0
REGS1_k127_1315647_1	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	7.195e-309	969.0
REGS1_k127_1315647_10	cellulose binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213	304.0
REGS1_k127_1315647_11	Aminotransferase class-V	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169	307.0
REGS1_k127_1315647_12	phosphatidate phosphatase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000528	205.0
REGS1_k127_1315647_13	Glycosyl hydrolases family 2	K01190	-	3.2.1.23	0.00000000000000000006187	91.0
REGS1_k127_1315647_14	Peptidase dimerisation domain	K12941	-	-	0.000006735	53.0
REGS1_k127_1315647_2	Beta-L-arabinofuranosidase, GH127	K09955	-	-	8.166e-228	722.0
REGS1_k127_1315647_3	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	K01262	-	3.4.11.9	6.225e-208	658.0
REGS1_k127_1315647_4	Converts alpha-aldose to the beta-anomer	K01785	-	5.1.3.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756	489.0
REGS1_k127_1315647_5	amino acid	K03294	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843	462.0
REGS1_k127_1315647_6	acetyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816	442.0
REGS1_k127_1315647_7	xylulokinase activity	K00854	-	2.7.1.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522	432.0
REGS1_k127_1315647_8	inositol 2-dehydrogenase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614	421.0
REGS1_k127_1315647_9	PFAM Amidohydrolase 2	K03392,K07045	-	4.1.1.45	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636	398.0
REGS1_k127_1338883_0	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	1.228e-245	774.0
REGS1_k127_1338883_1	nitrite transmembrane transporter activity	K02575,K10850	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544	471.0
REGS1_k127_1338883_2	aminopeptidase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349	373.0
REGS1_k127_1338883_3	Amidohydrolase family	K01465,K01466	-	3.5.2.3,3.5.2.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651	364.0
REGS1_k127_1338883_4	Thiamine-binding protein	-	-	-	0.00000000000000000000000000000000000000000000004098	170.0
REGS1_k127_1338883_5	AroM protein	K14591	-	-	0.0000000000000000000000001194	115.0
REGS1_k127_1338883_6	-	-	-	-	0.000000000000004927	89.0
REGS1_k127_1338883_7	-	-	-	-	0.00000006349	57.0
REGS1_k127_1338883_8	metallopeptidase activity	-	-	-	0.0001385	46.0
REGS1_k127_1395174_0	Putative esterase	-	-	-	8.513e-268	837.0
REGS1_k127_1395174_1	Transporter, CPA2 family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686	355.0
REGS1_k127_1395174_2	Di-iron-containing protein involved in the repair of iron-sulfur clusters	K07322	-	-	0.00000000000000000000000000003179	121.0
REGS1_k127_1395174_3	positive regulation of macromolecule biosynthetic process	K03973	-	-	0.0000000000002876	83.0
REGS1_k127_140244_0	Radical SAM superfamily	K04070	-	1.97.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224	345.0
REGS1_k127_140244_1	Nicotinamidase	K08281	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.1.19	0.00000000000000000000000000000000000000000000000000000000000000000000000007317	252.0
REGS1_k127_140244_2	Mut7-C ubiquitin	K09122	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000009633	245.0
REGS1_k127_140244_3	Adenosine specific kinase	K09129	-	-	0.00000000000000000000000000000000000000000000000000000000000000000001623	239.0
REGS1_k127_140244_4	Saccharopine dehydrogenase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000002092	250.0
REGS1_k127_140244_5	Stage II sporulation protein E	K07315	-	3.1.3.3	0.00000000000000000000000000000000000000000000001059	195.0
REGS1_k127_140244_6	PFAM Aminotransferase class-III	K01845	-	5.4.3.8	0.00000000000000002959	84.0
REGS1_k127_140244_7	cell adhesion involved in biofilm formation	-	-	-	0.00000000000007408	87.0
REGS1_k127_146717_0	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	K06978	-	-	5.244e-250	800.0
REGS1_k127_146717_1	epimerase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166	365.0
REGS1_k127_146717_2	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	0.0000000000000000000000000000000000000004934	161.0
REGS1_k127_146717_3	alpha/beta hydrolase fold	-	-	-	0.0000000000007335	76.0
REGS1_k127_146717_4	Pyridoxamine 5'-phosphate oxidase	K07006	-	-	0.000001323	60.0
REGS1_k127_1540050_0	glycoside hydrolase family 38	K01191	-	3.2.1.24	0.0	1489.0
REGS1_k127_1540050_1	Spermine/spermidine synthase domain	-	-	-	2.945e-287	908.0
REGS1_k127_1540050_2	COGs COG1629 Outer membrane receptor protein mostly Fe transport	K02014	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001529	249.0
REGS1_k127_1540050_3	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	K00036	-	1.1.1.363,1.1.1.49	0.000000000000000000000000000000000000000000000000000000000000000000007781	238.0
REGS1_k127_1540050_4	Glycosyl hydrolase family 47	K01230	-	3.2.1.113	0.0000000000000000000000000000022	129.0
REGS1_k127_1540050_5	Glycosyl hydrolase family 47	K01230	-	3.2.1.113	0.000000000000000000000000001147	122.0
REGS1_k127_1540050_6	Phosphoglycerate mutase	-	-	-	0.000001894	53.0
REGS1_k127_155714_0	Dehydrogenase E1 component	K11381	-	1.2.4.4	1.683e-281	886.0
REGS1_k127_155714_1	PASTA domain	K03587	-	3.4.16.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987	461.0
REGS1_k127_155714_10	Belongs to the peptidase M48B family	K03799	-	-	0.000000000000000000000000000000000000000000000000000000000000000000004089	248.0
REGS1_k127_155714_11	LemA family	K03744	-	-	0.00000000000000000000000000000000000000000000000000000000001676	212.0
REGS1_k127_155714_12	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	K01925	-	6.3.2.9	0.000000000000000000000000000000000000000000000000000000437	202.0
REGS1_k127_155714_13	Rhomboid family	-	-	-	0.00000000000000000000000000000000000000000000000003645	187.0
REGS1_k127_155714_14	Belongs to the MraZ family	K03925	-	-	0.000000000000000000000000000000000000000692	152.0
REGS1_k127_155714_15	Major Facilitator Superfamily	K08223	-	-	0.0000000000000000000000000000000000000007005	167.0
REGS1_k127_155714_16	PFAM Cupin 2, conserved barrel	-	-	-	0.0000000000000000000000000000000000001048	145.0
REGS1_k127_155714_17	Yqey-like protein	K09117	-	-	0.0000000000000000000000000000003809	128.0
REGS1_k127_155714_18	phosphinothricin N-acetyltransferase activity	-	-	-	0.000000000000000000002202	107.0
REGS1_k127_155714_19	Evidence 5 No homology to any previously reported sequences	-	-	-	0.000001013	59.0
REGS1_k127_155714_2	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	K03980	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746	417.0
REGS1_k127_155714_20	TQO small subunit DoxD	K16937	-	1.8.5.2	0.00001241	57.0
REGS1_k127_155714_21	(Type IV) pilus	K02507,K02666	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	0.0003849	51.0
REGS1_k127_155714_3	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	K01928	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918	426.0
REGS1_k127_155714_4	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	K01000	-	2.7.8.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716	411.0
REGS1_k127_155714_5	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	K06942	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882	321.0
REGS1_k127_155714_6	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	K03438	-	2.1.1.199	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004666	290.0
REGS1_k127_155714_7	Dehydrogenase reductase sdr	K00059	-	1.1.1.100	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126	282.0
REGS1_k127_155714_8	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	K01929	-	6.3.2.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000127	281.0
REGS1_k127_155714_9	Glycosyltransferase like family 2	K00721	-	2.4.1.83	0.0000000000000000000000000000000000000000000000000000000000000000000000002223	254.0
REGS1_k127_1665578_0	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265	490.0
REGS1_k127_1665578_1	Serine carboxypeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121	438.0
REGS1_k127_1665578_2	Penicillin	K01434	-	3.5.1.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435	447.0
REGS1_k127_1665578_3	ASPIC and UnbV	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479	433.0
REGS1_k127_1665578_4	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903	368.0
REGS1_k127_1665578_5	Beta-lactamase superfamily domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001869	243.0
REGS1_k127_1665578_6	serine-type endopeptidase activity	K08372	-	-	0.000000000000000000000000000000000000000000000000000000000000000199	236.0
REGS1_k127_1667775_0	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	K03703	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618	497.0
REGS1_k127_1667775_1	Tryptophanyl-tRNA synthetase	K01867	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304	379.0
REGS1_k127_1667775_2	thymidine kinase activity	K00857	GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	0.000000000000000000000000000000000000000000000000000000000000000000196	235.0
REGS1_k127_1667775_3	Belongs to the pseudouridine synthase RsuA family	K06178	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	0.000000000000000000000000000000000000000000000000000000000000004725	228.0
REGS1_k127_1667775_4	carboxylic ester hydrolase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000002716	210.0
REGS1_k127_1667775_5	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	K05896	-	-	0.0000000000000000000000000000000000000000000000000000000000806	217.0
REGS1_k127_1667775_6	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	K00995	-	2.7.8.5	0.000000000000000000000000000000000000000000000000000002758	198.0
REGS1_k127_1667775_7	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	K06024	-	-	0.000000000000000000000000000000000000000000000006232	179.0
REGS1_k127_1667775_8	Peptidase M50	-	-	-	0.00000000000000000000000000000000000000000000002183	178.0
REGS1_k127_1667775_9	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	K02356	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	0.0000000000000000000005744	96.0
REGS1_k127_1752842_0	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	K21071	-	2.7.1.11,2.7.1.90	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273	417.0
REGS1_k127_1752842_1	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	K02838	-	-	0.000000000000000000000000000000000000000000000000000000000364	207.0
REGS1_k127_1752842_2	peptidase S1 and S6, chymotrypsin Hap	K04771	-	3.4.21.107	0.0000000000000000000000000000000000000000000000000004413	204.0
REGS1_k127_1752842_3	Regulatory protein, FmdB family	-	-	-	0.0000000000000000006906	89.0
REGS1_k127_1842714_0	Carboxyl transferase domain	K01966	-	2.1.3.15,6.4.1.3	2.178e-241	754.0
REGS1_k127_1842714_1	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	K03667	-	-	1.707e-199	631.0
REGS1_k127_1842714_2	Pfam:CPSase_L_chain	K01961	-	6.3.4.14,6.4.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425	487.0
REGS1_k127_1842714_3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	K00616	-	2.2.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243	289.0
REGS1_k127_1842714_4	fumarylacetoacetate (FAA) hydrolase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000004536	265.0
REGS1_k127_1842714_5	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	K01419	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	3.4.25.2	0.0000000000000000000000000000000000000000000000000000000000000000000006534	241.0
REGS1_k127_1842714_6	Fibronectin type 3 domain	-	-	-	0.0000000000000000000004396	109.0
REGS1_k127_1842714_7	Biotin-requiring enzyme	-	-	-	0.0000000000000000001771	102.0
REGS1_k127_1888828_0	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	K00281,K00283	-	1.4.4.2	0.0	1217.0
REGS1_k127_1888828_1	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	K03070	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	0.0	1095.0
REGS1_k127_1888828_10	Lysin motif	K08307	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986	366.0
REGS1_k127_1888828_11	PFAM Type II secretion system F domain	K02653	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236	313.0
REGS1_k127_1888828_12	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	K00826	-	2.6.1.42	0.0000000000000000000000000000000000000000000000000000000000000000000000009332	256.0
REGS1_k127_1888828_13	Type ii and iii secretion system protein	K02453	-	-	0.0000000000000000000000000000000000000000001762	171.0
REGS1_k127_1888828_14	PFAM Peptidase M23	-	-	-	0.000000000000000000000000000000000000000007346	165.0
REGS1_k127_1888828_15	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	K02437	-	-	0.00000000000000000000000000000000000000001814	156.0
REGS1_k127_1888828_16	Carbon dioxide concentrating mechanism carboxysome shell protein	K04027	-	-	0.000000000000000000000000000000000000001612	149.0
REGS1_k127_1888828_17	PFAM Lytic transglycosylase catalytic	K08309	-	-	0.000000000000000000000000000000000000001616	154.0
REGS1_k127_1888828_18	Threonylcarbamoyl adenosine biosynthesis protein TsaE	K06925	-	-	0.000000000000000000000000001881	126.0
REGS1_k127_1888828_19	ABC transporter	K01990,K20490	-	-	0.00000000000000000000000001158	119.0
REGS1_k127_1888828_2	PFAM Type II secretion system protein E	K02652	-	-	3.817e-227	717.0
REGS1_k127_1888828_20	Asp/Glu/Hydantoin racemase	K01779	-	5.1.1.13	0.0000000000000000000000003321	123.0
REGS1_k127_1888828_21	Pilus assembly protein	K02662	-	-	0.000000000000000000000377	111.0
REGS1_k127_1888828_22	PFAM Fimbrial assembly family protein	K02663	-	-	0.00001201	58.0
REGS1_k127_1888828_23	-	-	-	-	0.00002779	53.0
REGS1_k127_1888828_24	Sulfatase	K01133	-	3.1.6.6	0.0001108	53.0
REGS1_k127_1888828_3	Peptidase S46	-	-	-	1.883e-211	679.0
REGS1_k127_1888828_4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	K00088	-	1.1.1.205	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008813	572.0
REGS1_k127_1888828_5	Magnesium chelatase, subunit ChlI C-terminal	K07391	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201	517.0
REGS1_k127_1888828_6	TIGRFAM acetaldehyde dehydrogenase (acetylating)	K00132	-	1.2.1.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442	490.0
REGS1_k127_1888828_7	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	K17758,K17759	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107	442.0
REGS1_k127_1888828_8	The glycine cleavage system catalyzes the degradation of glycine	K00605	-	2.1.2.10	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008	422.0
REGS1_k127_1888828_9	SMART Elongator protein 3 MiaB NifB	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155	402.0
REGS1_k127_1925839_0	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	K00179	-	1.2.7.8	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338	599.0
REGS1_k127_1925839_1	Surface antigen	K07277,K09800	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813	561.0
REGS1_k127_1925839_2	synthetase (ADP forming), alpha	K01905,K09181,K22224	-	6.2.1.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091	547.0
REGS1_k127_1925839_3	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	K00180	-	1.2.7.8	0.0000000000000000000000000000000000000000000000000000000298	203.0
REGS1_k127_1925839_4	TPR repeat-containing protein	-	-	-	0.0001424	52.0
REGS1_k127_1985891_0	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	K02358	-	-	4.762e-195	616.0
REGS1_k127_1985891_1	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	K02314	-	3.6.4.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347	524.0
REGS1_k127_1985891_10	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	K01775	-	5.1.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000233	268.0
REGS1_k127_1985891_11	Tetratricopeptide repeat	-	-	-	0.000000000000000000000000000000000000000000000000000000004734	223.0
REGS1_k127_1985891_12	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	K03218	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	0.0000000000000000000000000000000000000000000000000000002805	218.0
REGS1_k127_1985891_13	O-Antigen ligase	K18814	-	-	0.0000000000000000000000000000000000000000000000000005318	200.0
REGS1_k127_1985891_14	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	K01056	-	3.1.1.29	0.000000000000000000000000000000000000000000000000005098	187.0
REGS1_k127_1985891_15	dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	0.000000000000000000000000000000000000000000000000009133	200.0
REGS1_k127_1985891_16	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	K02897	-	-	0.00000000000000000000000000000000000000000000000008774	190.0
REGS1_k127_1985891_17	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	K00919	-	2.7.1.148	0.0000000000000000000000000000000000000000000000003017	187.0
REGS1_k127_1985891_18	Phosphate acyltransferases	K00655	-	2.3.1.51	0.000000000000000000000000000000000000000000004161	173.0
REGS1_k127_1985891_19	binds to the 23S rRNA	K02939	-	-	0.000000000000000000000000000000000001535	146.0
REGS1_k127_1985891_2	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	K04485	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564	514.0
REGS1_k127_1985891_20	B3 4 domain protein	-	-	-	0.00000000000000000000000000001062	136.0
REGS1_k127_1985891_21	'Cold-shock' DNA-binding domain	K03704	-	-	0.000000000000000000000000007213	114.0
REGS1_k127_1985891_22	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	K02963	-	-	0.000000000000000000000019	103.0
REGS1_k127_1985891_23	Binds together with S18 to 16S ribosomal RNA	K02990	-	-	0.00000000000000000003097	98.0
REGS1_k127_1985891_24	Trm112p-like protein	K00912,K09791	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.1.130	0.000000000000000001221	87.0
REGS1_k127_1985891_25	Belongs to the bacterial ribosomal protein bL33 family	K02913	-	-	0.00000000000000008374	82.0
REGS1_k127_1985891_26	-	-	-	-	0.0000000000000836	81.0
REGS1_k127_1985891_29	-	-	-	-	0.00006735	46.0
REGS1_k127_1985891_3	Bifunctional purine biosynthesis protein PurH	K00602	-	2.1.2.3,3.5.4.10	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255	511.0
REGS1_k127_1985891_4	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	K01885,K09698	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.17,6.1.1.24	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208	473.0
REGS1_k127_1985891_5	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	K00948	-	2.7.6.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836	396.0
REGS1_k127_1985891_6	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	K01042	-	2.9.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365	400.0
REGS1_k127_1985891_7	Large family of predicted nucleotide-binding domains	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466	372.0
REGS1_k127_1985891_8	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	K01770,K12506	-	2.7.7.60,4.6.1.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387	325.0
REGS1_k127_1985891_9	Phosphomethylpyrimidine kinase	K03272	-	2.7.1.167,2.7.7.70	0.0000000000000000000000000000000000000000000000000000000000000000000000000001269	269.0
REGS1_k127_2006325_0	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	K01338	-	3.4.21.53	3.737e-242	771.0
REGS1_k127_2006325_1	Creatinase/Prolidase N-terminal domain	K01271	-	3.4.13.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043	547.0
REGS1_k127_2006325_2	3-oxoacyl-[acyl-carrier-protein] synthase activity	K09458	-	2.3.1.179	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025	396.0
REGS1_k127_2006325_3	Glucose inhibited division protein A	K21401	-	1.3.99.38	0.0000000000000000000000000000000000000000000000000000001354	212.0
REGS1_k127_2006325_4	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	K00817	-	2.6.1.9	0.000000000000000000000000000000000000000000000000000005499	205.0
REGS1_k127_2006325_5	ubiE/COQ5 methyltransferase family	K00570	-	2.1.1.17,2.1.1.71	0.00000000000000000000000000000000000000000000000000004941	193.0
REGS1_k127_2006325_6	methyltransferase activity	K21310	-	2.1.1.334	0.0000000000000000000000000000000001754	142.0
REGS1_k127_2006325_7	von Willebrand factor, type A	K07114	-	-	0.000000000000000000000000003501	121.0
REGS1_k127_2006325_8	Isoprenylcysteine carboxyl methyltransferase	K16168	-	-	0.0000000000000000002512	100.0
REGS1_k127_231510_0	PFAM BNR Asp-box repeat	-	-	-	6.814e-267	854.0
REGS1_k127_231510_1	Amidohydrolase family	K06015	-	3.5.1.81	1.13e-229	723.0
REGS1_k127_231510_2	Peptidase dimerisation domain	K01439,K13049	-	3.5.1.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935	557.0
REGS1_k127_231510_3	Proline racemase	K01777	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564	5.1.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248	515.0
REGS1_k127_231510_4	FAD linked oxidase domain protein	K00102,K00104	-	1.1.2.4,1.1.3.15	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261	508.0
REGS1_k127_231510_5	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	K02274	-	1.9.3.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003	476.0
REGS1_k127_231510_6	Cytochrome C oxidase subunit II, periplasmic domain	K02275	-	1.9.3.1	0.0000000000000000000000000000000000000000000000000000000000000000000005995	246.0
REGS1_k127_231510_7	Thioredoxin	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000001489	243.0
REGS1_k127_231510_8	Cytochrome c oxidase subunit III	K02276	-	1.9.3.1	0.00000000000000000000000000000000000000000000000000000000000007285	218.0
REGS1_k127_231510_9	Bacterial regulatory proteins, tetR family	-	-	-	0.0000000000000000001181	96.0
REGS1_k127_2326091_0	DEAD-like helicases superfamily	K11927	-	3.6.4.13	5.262e-199	627.0
REGS1_k127_2326091_1	Nickel-dependent hydrogenase	K00436	-	1.12.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179	607.0
REGS1_k127_2326091_2	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	K16950	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308	472.0
REGS1_k127_2326091_3	2 iron, 2 sulfur cluster binding	K02823	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648	371.0
REGS1_k127_2326091_4	coenzyme F420 hydrogenase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163	370.0
REGS1_k127_2326091_5	cyclic nucleotide binding	K10914	-	-	0.000000000000000000000000000000000000000000000000000000001188	207.0
REGS1_k127_2326091_6	Hydrogenase maturation protease	-	-	-	0.00000000000000000000000002706	122.0
REGS1_k127_2326091_7	MarC family integral membrane protein	-	-	-	0.0000000000003743	73.0
REGS1_k127_2360629_0	Dienelactone hydrolase family	-	-	-	1.233e-241	766.0
REGS1_k127_2360629_1	Peptidase dimerisation domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053	400.0
REGS1_k127_2360629_2	NADPH quinone reductase and related Zn-dependent oxidoreductases	K00344	-	1.6.5.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218	335.0
REGS1_k127_2360629_3	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	K00611	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	0.00001242	49.0
REGS1_k127_2374259_0	TIGRFAM aminoacyl-histidine dipeptidase	K01270	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945	580.0
REGS1_k127_2374259_1	AMP-binding enzyme	K01897	-	6.2.1.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822	502.0
REGS1_k127_2374259_10	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	K03637	-	4.6.1.17	0.000000000000000000000000000000000000000000000000001781	188.0
REGS1_k127_2374259_11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00337,K00338	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	0.000000000000000000000000000000000000000001217	180.0
REGS1_k127_2374259_12	Belongs to the peptidase S26 family	K03100	-	3.4.21.89	0.0000000000000000000000000000000000003762	152.0
REGS1_k127_2374259_13	histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	0.0000000000000815	79.0
REGS1_k127_2374259_2	aldo keto reductase	K05275	-	1.1.1.65	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493	391.0
REGS1_k127_2374259_3	Histidine kinase internal region	K02478	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628	327.0
REGS1_k127_2374259_4	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005626	291.0
REGS1_k127_2374259_5	Belongs to the LOG family	K06966	-	3.2.2.10	0.0000000000000000000000000000000000000000000000000000000000000000000000000000001703	269.0
REGS1_k127_2374259_6	Two component transcriptional regulator, LytTR family	K02477,K07705	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000005602	254.0
REGS1_k127_2374259_7	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000002954	246.0
REGS1_k127_2374259_8	Domain of unknown function (DUF4159)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000003039	236.0
REGS1_k127_2374259_9	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	K01926	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	0.0000000000000000000000000000000000000000000000000000004159	200.0
REGS1_k127_2423477_0	Belongs to the citrate synthase family	K01647	-	2.3.3.1	1.108e-206	650.0
REGS1_k127_2423477_1	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	K01649	-	2.3.3.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065	460.0
REGS1_k127_2423477_10	Protein of unknown function DUF47	K02039,K07220	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	0.00000000000000000000000000000000000000000000000000000000000000003144	229.0
REGS1_k127_2423477_11	Peptidase family M28	-	-	-	0.0000000000000000000000000000000000000000000000000000000237	223.0
REGS1_k127_2423477_12	-	-	-	-	0.000000000000000000000000000000003034	143.0
REGS1_k127_2423477_13	Phosphohistidine phosphatase, SixA	K08296	-	-	0.00000000000000000000008067	104.0
REGS1_k127_2423477_14	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	K09862	-	-	0.000000008525	66.0
REGS1_k127_2423477_15	CHAD domain containing protein	-	-	-	0.00000003685	64.0
REGS1_k127_2423477_2	ABC 3 transport family	K02075	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943	378.0
REGS1_k127_2423477_3	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	K01524,K07012	-	3.6.1.11,3.6.1.40	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718	389.0
REGS1_k127_2423477_4	Zinc-uptake complex component A periplasmic	K02077	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755	345.0
REGS1_k127_2423477_5	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	K02036	-	3.6.3.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988	350.0
REGS1_k127_2423477_6	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	K00975	-	2.7.7.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001558	297.0
REGS1_k127_2423477_7	dTDP biosynthetic process	K00560,K00943,K01585	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000004675	279.0
REGS1_k127_2423477_8	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000003633	279.0
REGS1_k127_2423477_9	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	K00943	-	2.7.4.9	0.0000000000000000000000000000000000000000000000000000000000000000003591	238.0
REGS1_k127_2445797_0	UvrD/REP helicase N-terminal domain	-	-	-	2.244e-316	1009.0
REGS1_k127_2445797_1	Acetyl-coenzyme A synthetase N-terminus	K01908	-	6.2.1.17	3.33e-297	923.0
REGS1_k127_2445797_10	Oxidoreductase FAD-binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000007321	210.0
REGS1_k127_2445797_11	ferredoxin-NADP+ reductase activity	-	-	-	0.000000000000000000000000000000000000000001798	168.0
REGS1_k127_2445797_12	DinB family	-	-	-	0.0000000000000000000000000000000001323	139.0
REGS1_k127_2445797_2	lysine biosynthetic process via aminoadipic acid	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396	473.0
REGS1_k127_2445797_3	PD-(D/E)XK nuclease superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055	417.0
REGS1_k127_2445797_4	heat shock protein binding	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189	375.0
REGS1_k127_2445797_5	saccharopine dehydrogenase activity	K19064	-	1.4.1.18	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098	363.0
REGS1_k127_2445797_6	heat shock protein binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164	357.0
REGS1_k127_2445797_7	Methyltransferase domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000005649	243.0
REGS1_k127_2445797_8	Protein of unknown function (DUF1847)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000001884	221.0
REGS1_k127_2445797_9	WYL domain	K13572	-	-	0.000000000000000000000000000000000000000000000000000005502	204.0
REGS1_k127_2466061_0	Tricorn protease homolog	K08676	-	-	0.0	1526.0
REGS1_k127_2466061_1	catalase activity	K03781	-	1.11.1.6	5.67e-260	809.0
REGS1_k127_2466061_10	two component, sigma54 specific, transcriptional regulator, Fis family	K02481,K07713	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166	384.0
REGS1_k127_2466061_11	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	K03386	-	1.11.1.15	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494	329.0
REGS1_k127_2466061_12	Protein of unknown function DUF58	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891	318.0
REGS1_k127_2466061_13	Haemolysin-III related	K11068	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002216	286.0
REGS1_k127_2466061_14	Peptidase family M28	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008434	279.0
REGS1_k127_2466061_15	Aerotolerance regulator N-terminal	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007645	305.0
REGS1_k127_2466061_16	Redoxin	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001405	256.0
REGS1_k127_2466061_17	Domain of unknown function (DUF4159)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000217	262.0
REGS1_k127_2466061_18	PFAM PilT protein domain protein	-	-	-	0.00000000000000000000000000000000000000000000000001737	184.0
REGS1_k127_2466061_19	Peptidase C14 caspase catalytic subunit p20	-	-	-	0.0000000000000000000000000000000000000000000000005379	198.0
REGS1_k127_2466061_2	nuclear chromosome segregation	-	-	-	8.878e-199	661.0
REGS1_k127_2466061_20	Disulphide bond corrector protein DsbC	K04084	-	1.8.1.8	0.0000000000000000000000000000000000000000000001031	183.0
REGS1_k127_2466061_21	Histidine kinase	K13598	-	2.7.13.3	0.0000000000000000000000000000000000000001355	173.0
REGS1_k127_2466061_22	DoxX family	K15977	-	-	0.0000000000000000000000000000000003387	134.0
REGS1_k127_2466061_23	PFAM blue (type 1) copper domain protein	-	-	-	0.00000000000000000000000000000001912	145.0
REGS1_k127_2466061_24	-	-	-	-	0.000000000000000000000003383	116.0
REGS1_k127_2466061_25	STAS domain	K04749	-	-	0.0000000000000000000004913	100.0
REGS1_k127_2466061_26	SpoVT AbrB like domain	-	-	-	0.000000000000008132	77.0
REGS1_k127_2466061_27	Cupredoxin-like domain	-	-	-	0.00000000000002277	80.0
REGS1_k127_2466061_28	Heme copper-type cytochrome quinol oxidases, subunit 2	K02275	-	1.9.3.1	0.00000000009041	74.0
REGS1_k127_2466061_3	esterase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464	618.0
REGS1_k127_2466061_4	Putative glutamine amidotransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754	592.0
REGS1_k127_2466061_5	Beta-lactamase	K17836	-	3.5.2.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729	487.0
REGS1_k127_2466061_6	efflux transmembrane transporter activity	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068	485.0
REGS1_k127_2466061_7	Sodium:solute symporter family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497	451.0
REGS1_k127_2466061_8	mismatched DNA binding	K03555	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543	463.0
REGS1_k127_2466061_9	ATPase family associated with various cellular activities (AAA)	K03924	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642	436.0
REGS1_k127_2492883_0	May be involved in recombinational repair of damaged DNA	K03631	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505	413.0
REGS1_k127_2492883_1	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	K06168	-	2.8.4.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745	372.0
REGS1_k127_2492883_2	Cobyrinic acid ac-diamide synthase	K03496	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512	299.0
REGS1_k127_2492883_3	TolB amino-terminal domain	K03641	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	0.00000000000000000000000000000000000000000000000000000000000000007605	248.0
REGS1_k127_2492883_4	Bifunctional nuclease	K08999	-	-	0.000000000000000000000000000000000000000000000000000000000169	209.0
REGS1_k127_2492883_5	chromosome segregation	K03497	-	-	0.0000000000000000000000000000000000000000000000000000000005861	213.0
REGS1_k127_2492883_6	MotA TolQ ExbB proton channel	K03562	-	-	0.00000000000000000000000000000000000000000000000000008196	205.0
REGS1_k127_2492883_7	OmpA family	K03640	-	-	0.0000000000000000000000000000000005857	143.0
REGS1_k127_2492883_8	Biopolymer transport protein ExbD/TolR	K03559,K03560	-	-	0.0000000000000000000002983	102.0
REGS1_k127_2492883_9	TonB C terminal	K03832	-	-	0.000005418	57.0
REGS1_k127_2658223_0	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	K15726	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497	587.0
REGS1_k127_2658223_1	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K15727	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591	425.0
REGS1_k127_2658223_2	Outer membrane efflux protein	K15725	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151	323.0
REGS1_k127_2658223_3	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	K03116,K03117,K03646	-	-	0.0000000000000871	75.0
REGS1_k127_2880548_0	Two component, sigma54 specific, transcriptional regulator, Fis family	K13599	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198	534.0
REGS1_k127_2880548_1	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	K04077	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104	493.0
REGS1_k127_2880548_2	histidine kinase HAMP region domain protein	K13598	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859	439.0
REGS1_k127_2880548_3	PFAM SAICAR synthetase	K01923,K13713	-	6.3.2.6,6.3.4.13	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145	390.0
REGS1_k127_2880548_4	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	K07738	-	-	0.00000000000000000000000000000000000000000000000000000534	209.0
REGS1_k127_2880548_5	Lysylphosphatidylglycerol synthase TM region	K07027	-	-	0.000000000000000000000000000000000000000149	165.0
REGS1_k127_2880548_6	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	K04078	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	0.00000000000000000000000000000000000003398	146.0
REGS1_k127_2880548_7	Bacterial regulatory protein, Fis family	-	-	-	0.000000000008008	68.0
REGS1_k127_2880548_8	-	-	-	-	0.0000000000373	75.0
REGS1_k127_2880548_9	Domain of unknown function (DUF4390)	-	-	-	0.0000000006558	69.0
REGS1_k127_2921646_0	Melibiase	K07407	-	3.2.1.22	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278	506.0
REGS1_k127_2921646_1	lysine biosynthetic process via aminoadipic acid	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891	501.0
REGS1_k127_2921646_10	COG1668 ABC-type Na efflux pump, permease component	K01992,K09696	-	-	0.000000000000000000000000000000000000000000322	174.0
REGS1_k127_2921646_11	Protein of Unknown function (DUF2784)	-	-	-	0.00000000000000000000000000000000000003386	147.0
REGS1_k127_2921646_12	positive regulation of growth	K01081	-	3.1.3.5	0.000000000000000002344	87.0
REGS1_k127_2921646_13	Rieske [2Fe-2S] domain	-	-	-	0.000000000000411	79.0
REGS1_k127_2921646_2	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366	468.0
REGS1_k127_2921646_3	COG0659 Sulfate permease and related transporters (MFS	K03321	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136	391.0
REGS1_k127_2921646_4	Isocitrate dehydrogenase	K00031	-	1.1.1.42	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495	325.0
REGS1_k127_2921646_5	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006263	292.0
REGS1_k127_2921646_6	ABC transporter	K01990,K09697	-	3.6.3.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000003182	278.0
REGS1_k127_2921646_7	PIN domain	-	-	-	0.000000000000000000000000000000000000000000000000001298	190.0
REGS1_k127_2921646_8	COG1668 ABC-type Na efflux pump, permease component	K01992,K09696	-	-	0.00000000000000000000000000000000000000000000003915	195.0
REGS1_k127_2921646_9	-	-	-	-	0.0000000000000000000000000000000000000000002892	165.0
REGS1_k127_2979010_0	acyl-CoA transferase carnitine dehydratase	K18702	-	2.8.3.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908	467.0
REGS1_k127_2979010_1	Aminotransferase class I and II	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816	391.0
REGS1_k127_2979010_2	Type II/IV secretion system protein	K02669	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001462	306.0
REGS1_k127_2979010_3	homoserine dehydrogenase	K00003	-	1.1.1.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000001679	278.0
REGS1_k127_2979010_4	Sulfatase-modifying factor enzyme 1	-	-	-	0.0000000000000000000000000000000000000000000000002718	186.0
REGS1_k127_2979010_5	Protein of unknown function (DUF541)	K09807	-	-	0.00000000000000000001054	101.0
REGS1_k127_297931_0	serine-type peptidase activity	-	-	-	9.607e-262	840.0
REGS1_k127_297931_1	Carbohydrate phosphorylase	K00688	-	2.4.1.1	3.895e-251	793.0
REGS1_k127_297931_10	Beta-lactamase	-	-	-	0.0000000000000000000000002178	117.0
REGS1_k127_297931_11	PrcB C-terminal	-	-	-	0.00000000000000003365	87.0
REGS1_k127_297931_12	Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'- monophosphates containing purine bases are preferred to those containing pyrimidine bases	-	GO:0001558,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030307,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040008,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045927,GO:0046434,GO:0046483,GO:0046700,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0055086,GO:0065007,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	0.000000009807	65.0
REGS1_k127_297931_2	aminopeptidase activity	K01266	-	3.4.11.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901	535.0
REGS1_k127_297931_3	asparaginase	K01424,K01444,K13051	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606	496.0
REGS1_k127_297931_4	Aspartate-ammonia ligase	K01914	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364	417.0
REGS1_k127_297931_5	lysine biosynthetic process via aminoadipic acid	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703	417.0
REGS1_k127_297931_6	beta' subunit	K01754	-	4.3.1.19	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278	285.0
REGS1_k127_297931_7	Aminoacyl-tRNA editing domain	K19055	-	-	0.00000000000000000000000000000000000000000000000000000003233	201.0
REGS1_k127_297931_8	Pseudouridine synthase	K06177,K06180	-	5.4.99.23,5.4.99.28,5.4.99.29	0.0000000000000000000000000000000000000000000008349	178.0
REGS1_k127_297931_9	dUTP diphosphatase activity	K01520,K13038	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23,4.1.1.36,6.3.2.5	0.00000000000000000000000000000001843	139.0
REGS1_k127_2998385_0	Uncharacterised protein family (UPF0182)	K09118	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	1.04e-257	822.0
REGS1_k127_2998385_1	signal peptide processing	K03100	-	3.4.21.89	0.000000000000000000000000000000000000000632	154.0
REGS1_k127_3056464_0	efflux transmembrane transporter activity	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931	501.0
REGS1_k127_3056464_1	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	K00648	-	2.3.1.180	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357	398.0
REGS1_k127_3056464_2	COGs COG1629 Outer membrane receptor protein mostly Fe transport	K02014	-	-	0.0000000000000000000001835	108.0
REGS1_k127_3056464_3	-	-	-	-	0.00000000008281	71.0
REGS1_k127_3174105_0	Dehydrogenase	K00117,K19813	-	1.1.5.2,1.1.5.9	1.833e-208	671.0
REGS1_k127_3174105_1	efflux transmembrane transporter activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096	485.0
REGS1_k127_3174105_10	Protein of unknown function (DUF2911)	-	-	-	0.000000000000000000000000000000000000007809	151.0
REGS1_k127_3174105_11	-	-	-	-	0.00000000000000000000000000000005966	132.0
REGS1_k127_3174105_12	aminopeptidase activity	K05994	-	3.4.11.10	0.0000000000000000000002934	107.0
REGS1_k127_3174105_2	Major facilitator Superfamily	K08178	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304	472.0
REGS1_k127_3174105_3	Amidase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956	351.0
REGS1_k127_3174105_4	Carboxypeptidase regulatory-like domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166	330.0
REGS1_k127_3174105_5	Enoyl-(Acyl carrier protein) reductase	K00059	-	1.1.1.100	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001055	295.0
REGS1_k127_3174105_6	TIGRFAM zinc-binding alcohol dehydrogenase family protein	K13953	-	1.1.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002337	282.0
REGS1_k127_3174105_7	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000002028	283.0
REGS1_k127_3174105_8	Penicillin	K01434	-	3.5.1.11	0.000000000000000000000000000000000000000000000000000000000000000000000000002224	265.0
REGS1_k127_3174105_9	OsmC-like protein	K09136	-	-	0.000000000000000000000000000000000000000000000000000002257	194.0
REGS1_k127_3178299_0	Transglycosylase	K05366	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769	600.0
REGS1_k127_3178299_1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	K02836	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011	412.0
REGS1_k127_3178299_2	Transfers the fatty acyl group on membrane lipoproteins	K03820	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344	372.0
REGS1_k127_3229015_0	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	K00163	-	1.2.4.1	0.0	1053.0
REGS1_k127_3229015_1	Peptidase family M49	-	-	-	4.989e-221	699.0
REGS1_k127_3229015_10	PFAM peptidase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799	336.0
REGS1_k127_3229015_11	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	K03783	-	2.4.2.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369	326.0
REGS1_k127_3229015_12	AAA domain, putative AbiEii toxin, Type IV TA system	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389	328.0
REGS1_k127_3229015_13	ATPase activity	K01990,K19340	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411	333.0
REGS1_k127_3229015_14	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	K01409	-	2.3.1.234	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261	315.0
REGS1_k127_3229015_15	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	K01754	-	4.3.1.19	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781	302.0
REGS1_k127_3229015_16	gtp cyclohydrolase	K00950,K01495	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659	2.7.6.3,3.5.4.16	0.000000000000000000000000000000000000000000000000000000000000000000000000000002428	266.0
REGS1_k127_3229015_17	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000008675	258.0
REGS1_k127_3229015_18	Uncharacterised protein family UPF0047	-	-	-	0.00000000000000000000000000000000000000000000000000000000000002651	217.0
REGS1_k127_3229015_19	Glycerophosphoryl diester phosphodiesterase family	K01126	-	3.1.4.46	0.0000000000000000000000000000000000000000000000000001197	198.0
REGS1_k127_3229015_2	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	K03405	-	6.6.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553	619.0
REGS1_k127_3229015_20	ATP-dependent protease La (LON) substrate-binding domain	K07157	-	-	0.0000000000000000000000000000000000001263	165.0
REGS1_k127_3229015_21	Cytidine and deoxycytidylate deaminase zinc-binding region	K01489	-	3.5.4.5	0.000000000000000000000000000000000006879	150.0
REGS1_k127_3229015_22	NUDIX domain	-	-	-	0.00000000000000000000000000000000002717	148.0
REGS1_k127_3229015_23	ABC-2 family transporter protein	K01992	-	-	0.0000000000000000000000000008638	130.0
REGS1_k127_3229015_24	-	-	-	-	0.00000000000000001822	94.0
REGS1_k127_3229015_25	PFAM AIG2 family protein	K20757	-	4.3.1.27	0.000000000000000067	85.0
REGS1_k127_3229015_26	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	K03317,K16324	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642	-	0.00000000004286	63.0
REGS1_k127_3229015_27	-	K01992	-	-	0.0000000006485	70.0
REGS1_k127_3229015_3	von Willebrand factor (vWF) type A domain	K07114	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326	516.0
REGS1_k127_3229015_4	Thiolase, C-terminal domain	K00626	-	2.3.1.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994	456.0
REGS1_k127_3229015_5	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	K08963	-	5.3.1.23	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445	412.0
REGS1_k127_3229015_6	Belongs to the thiolase family	K00626	-	2.3.1.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445	407.0
REGS1_k127_3229015_7	Isocitrate/isopropylmalate dehydrogenase	K00052	-	1.1.1.85	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673	381.0
REGS1_k127_3229015_8	3-hydroxyacyl-CoA dehydrogenase domain protein	K00074	-	1.1.1.157	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024	375.0
REGS1_k127_3229015_9	L-lysine 6-monooxygenase (NADPH-requiring)	K00384	-	1.8.1.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301	339.0
REGS1_k127_3435532_0	efflux transmembrane transporter activity	-	-	-	1.704e-208	677.0
REGS1_k127_3435532_1	Pfam Anion-transporting ATPase	K01551	-	3.6.3.16	1.102e-196	626.0
REGS1_k127_3435532_10	PFAM Acetyltransferase (GNAT) family	K03790	-	2.3.1.128	0.000000000000000000000000000002069	128.0
REGS1_k127_3435532_11	helix_turn_helix, Arsenical Resistance Operon Repressor	K03892	-	-	0.000000000000000000000000001104	117.0
REGS1_k127_3435532_12	Cupin domain	-	-	-	0.00000000000000000000001263	104.0
REGS1_k127_3435532_14	helix_turn_helix, Arsenical Resistance Operon Repressor	K03892	-	-	0.000000000009348	72.0
REGS1_k127_3435532_2	PFAM acetyl-CoA hydrolase transferase	K01067	-	3.1.2.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467	561.0
REGS1_k127_3435532_3	Sodium Bile acid symporter family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141	525.0
REGS1_k127_3435532_4	Cys/Met metabolism PLP-dependent enzyme	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048	475.0
REGS1_k127_3435532_5	PFAM aldo keto reductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686	433.0
REGS1_k127_3435532_6	Belongs to the AlaDH PNT family	K00259	-	1.4.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276	331.0
REGS1_k127_3435532_7	Universal stress protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000005384	250.0
REGS1_k127_3435532_8	Serine aminopeptidase, S33	K06889	-	-	0.000000000000000000000000000000000000000000000000000000000000000000002266	246.0
REGS1_k127_3435532_9	Di-iron-containing protein involved in the repair of iron-sulfur clusters	K07322	-	-	0.00000000000000000000000000000000000000000000000000000000000194	215.0
REGS1_k127_3466494_0	Glutamine synthetase type III	K01915	-	6.3.1.2	4.625e-299	933.0
REGS1_k127_3466494_1	Dienelactone hydrolase family	-	-	-	1.888e-224	730.0
REGS1_k127_3466494_10	histidine kinase A domain protein	K02482	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003843	298.0
REGS1_k127_3466494_11	Cytochrome C biogenesis protein transmembrane region	K06196,K12267	-	1.8.4.11,1.8.4.12	0.0000000000000000000000000000000000000000000000000000000000000000000000001338	256.0
REGS1_k127_3466494_12	Glycosyl transferase family 2	K00721	-	2.4.1.83	0.00000000000000000000000000000000000000000000000000000000000000000000007159	253.0
REGS1_k127_3466494_13	CO dehydrogenase flavoprotein C-terminal domain	K11178	-	1.17.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000167	261.0
REGS1_k127_3466494_14	Potassium uptake protein	K03499	-	-	0.00000000000000000000000000000000000000000000000000000000000000000003519	240.0
REGS1_k127_3466494_15	6-O-methylguanine DNA methyltransferase, DNA binding domain	K00567	-	2.1.1.63	0.00000000000000000000000000000000000000000000000000000003257	202.0
REGS1_k127_3466494_16	Sigma factor PP2C-like phosphatases	K07315	-	3.1.3.3	0.0000000000000000000000000000000000000000000000000000005144	209.0
REGS1_k127_3466494_17	2Fe-2S -binding domain protein	K13483	-	-	0.0000000000000000000000000000000000000000000000000001377	195.0
REGS1_k127_3466494_18	Probably functions as a manganese efflux pump	-	-	-	0.00000000000000000000000000000000000000000000000009656	201.0
REGS1_k127_3466494_19	aminopeptidase	-	-	-	0.00000000000000000000000000000000000000001547	162.0
REGS1_k127_3466494_2	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	K11177	-	1.17.1.4	1.293e-208	670.0
REGS1_k127_3466494_20	Diacylglycerol kinase	-	-	-	0.0000000000000000000000000000000000000002705	161.0
REGS1_k127_3466494_21	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	K02372	-	4.2.1.59	0.00000000000000000000000000000000000002993	151.0
REGS1_k127_3466494_22	PDZ DHR GLGF domain protein	-	-	-	0.000000000000000000000000000000009467	140.0
REGS1_k127_3466494_23	Belongs to the ompA family	-	-	-	0.00000000000000000000004038	115.0
REGS1_k127_3466494_24	Protein of unknown function (DUF1326)	-	-	-	0.00000000000000000000009813	107.0
REGS1_k127_3466494_25	von Willebrand factor (vWF) type A domain	K07114	-	-	0.0000000000000000000005187	107.0
REGS1_k127_3466494_26	DoxX	K15977	-	-	0.0000000000000000001612	96.0
REGS1_k127_3466494_27	ACT domain protein	-	-	-	0.000000004289	63.0
REGS1_k127_3466494_29	-	-	-	-	0.00003034	49.0
REGS1_k127_3466494_3	PFAM glutamine synthetase catalytic region	K01915	-	6.3.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893	569.0
REGS1_k127_3466494_30	Peptidase family M1 domain	-	-	-	0.0001939	54.0
REGS1_k127_3466494_4	Aminotransferase class-V	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141	537.0
REGS1_k127_3466494_5	TIGRFAM potassium uptake protein, TrkH family	K03498	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915	397.0
REGS1_k127_3466494_6	Sigma factor PP2C-like phosphatases	K07315	-	3.1.3.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469	383.0
REGS1_k127_3466494_7	Aminotransferase	K00812	-	2.6.1.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834	375.0
REGS1_k127_3466494_8	ATP synthesis coupled electron transport	K00336	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281	375.0
REGS1_k127_3466494_9	Dehydrogenase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751	314.0
REGS1_k127_3469343_0	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	K02335	-	2.7.7.7	5.506e-231	746.0
REGS1_k127_3469343_1	ATPase activity	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016	356.0
REGS1_k127_3469343_2	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	K00970,K00974	-	2.7.7.19,2.7.7.72	0.000000000000000000000000000000000000000000000000000000000000000000000000000000003023	286.0
REGS1_k127_3469343_3	ABC-2 family transporter protein	K01992	-	-	0.00000000000000000000000000000000000000000000000000000000000001809	238.0
REGS1_k127_3469343_4	PFAM Fatty acid desaturase	K00507	-	1.14.19.1	0.000000000000000000000000000000000000000000000000000000001678	213.0
REGS1_k127_3469343_5	Carboxypeptidase regulatory-like domain	-	-	-	0.00000000000000000000000000000000000000000000000000000001428	220.0
REGS1_k127_3469343_6	BON domain	-	-	-	0.00000000000000000000000000003108	123.0
REGS1_k127_3469343_7	Acetyltransferase (GNAT) family	-	-	-	0.000000000000000001141	96.0
REGS1_k127_3469343_8	Bacterial regulatory protein, Fis family	K13599	-	-	0.000000002244	69.0
REGS1_k127_3470245_0	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	K01972	-	6.5.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169	536.0
REGS1_k127_3470245_1	Trimethylamine methyltransferase (MTTB)	K14083	-	2.1.1.250	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278	416.0
REGS1_k127_3470245_10	Thioredoxin domain	-	-	-	0.0000000000000000000002388	97.0
REGS1_k127_3470245_11	PFAM Vitamin B12 dependent methionine synthase, activation	-	-	-	0.0000000000000004029	93.0
REGS1_k127_3470245_2	PFAM Aminotransferase class-III	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812	332.0
REGS1_k127_3470245_3	Sigma factor PP2C-like phosphatases	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001486	287.0
REGS1_k127_3470245_4	KR domain	K00059,K18009	-	1.1.1.100,1.1.1.304,1.1.1.76	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003146	282.0
REGS1_k127_3470245_5	Enoyl-(Acyl carrier protein) reductase	K00059,K18009	-	1.1.1.100,1.1.1.304,1.1.1.76	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002531	282.0
REGS1_k127_3470245_6	Methionine synthase B12-binding module cap domain protein	K00548	-	2.1.1.13	0.0000000000000000000000000000000000000000000000000000000000000000000001577	258.0
REGS1_k127_3470245_7	Methionine synthase B12-binding module cap domain protein	K00548	-	2.1.1.13	0.000000000000000000000000000000000000000000000000000000000000000000305	236.0
REGS1_k127_3470245_8	Nitroreductase family	-	-	-	0.00000000000000000000000000000000000000000000001346	177.0
REGS1_k127_3470245_9	Thioredoxin domain	-	-	-	0.00000000000000000000000000000000000000001734	167.0
REGS1_k127_3519749_0	membrane protein (DUF2207)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186	564.0
REGS1_k127_3519749_1	Cytochrome c3	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861	428.0
REGS1_k127_3519749_10	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	K07264	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016763,GO:0033692,GO:0034637,GO:0034645,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.2.43	0.000000000000000000000000000000000000000005082	178.0
REGS1_k127_3519749_11	phosphatase activity	K07025	-	-	0.000000000000000000000000000000001559	137.0
REGS1_k127_3519749_2	Histidine kinase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302	435.0
REGS1_k127_3519749_3	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921	351.0
REGS1_k127_3519749_4	ABC transporter	K01990,K09695	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393	346.0
REGS1_k127_3519749_5	helix_turn_helix, Lux Regulon	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806	294.0
REGS1_k127_3519749_6	denitrification pathway	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000002251	266.0
REGS1_k127_3519749_7	metalloendopeptidase activity	K03799	-	-	0.00000000000000000000000000000000000000000000000001197	192.0
REGS1_k127_3519749_8	LemA family	K03744	-	-	0.0000000000000000000000000000000000000000000000141	186.0
REGS1_k127_3519749_9	heme binding	K08259	-	3.4.24.75	0.00000000000000000000000000000000000000000000002482	185.0
REGS1_k127_3536294_0	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	K03737	-	1.2.7.1	0.0	1541.0
REGS1_k127_3536294_1	NapC/NirT cytochrome c family, N-terminal region	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745	442.0
REGS1_k127_3536294_10	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	0.000000000000000000000000006797	115.0
REGS1_k127_3536294_11	Tetratricopeptide repeat	-	-	-	0.000000000000000000000006756	109.0
REGS1_k127_3536294_12	PFAM sodium	K14445	-	-	0.000000000000000000004396	107.0
REGS1_k127_3536294_13	Radical SAM	-	-	-	0.0004054	48.0
REGS1_k127_3536294_2	Carbohydrate family 9 binding domain-like	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994	444.0
REGS1_k127_3536294_3	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	K00763	-	6.3.4.21	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842	389.0
REGS1_k127_3536294_4	formate dehydrogenase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465	336.0
REGS1_k127_3536294_5	Phosphoribulokinase / Uridine kinase family	K00855,K00876	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.19,2.7.1.48	0.000000000000000000000000000000000000000000000000000000000000000000000000004331	261.0
REGS1_k127_3536294_6	Cytochrome c554 and c-prime	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000082	262.0
REGS1_k127_3536294_7	TonB-dependent receptor	K02014	-	-	0.0000000000000000000000000000000000000000000000008267	200.0
REGS1_k127_3536294_8	PFAM phospholipase Carboxylesterase	-	-	-	0.0000000000000000000000000000000000000000002669	166.0
REGS1_k127_3536294_9	OsmC-like protein	-	-	-	0.000000000000000000000000001429	127.0
REGS1_k127_3616197_0	Surface antigen variable number	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502	343.0
REGS1_k127_3616197_1	TamB, inner membrane protein subunit of TAM complex	K09800	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000006057	299.0
REGS1_k127_3616197_2	Abortive infection protein	K07052	-	-	0.000828	50.0
REGS1_k127_3633473_0	MacB-like periplasmic core domain	-	-	-	0.0	1011.0
REGS1_k127_3633473_1	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	0.000000000000000000000000000000000000000000003777	183.0
REGS1_k127_3633473_2	Cold shock protein domain	-	-	-	0.000000000000000002329	89.0
REGS1_k127_365534_0	metallocarboxypeptidase activity	-	-	-	8.298e-210	705.0
REGS1_k127_365534_1	Sugar (and other) transporter	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349	556.0
REGS1_k127_365534_2	PFAM amidohydrolase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872	431.0
REGS1_k127_365534_3	amidohydrolase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028	387.0
REGS1_k127_365534_4	LamB/YcsF family	K07160	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309	300.0
REGS1_k127_365534_5	PFAM Hydantoinase B oxoprolinase	K01474	-	3.5.2.14	0.00000000000000000000000000001874	124.0
REGS1_k127_365534_6	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	K10943	-	-	0.0000000000009754	74.0
REGS1_k127_3673341_0	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	K03296	-	-	0.0	1251.0
REGS1_k127_3673341_1	IgA Peptidase M64	-	-	-	1.877e-221	701.0
REGS1_k127_3673341_10	Toxic component of a toxin-antitoxin (TA) module. An RNase	K07065	-	-	0.00000000000000001927	96.0
REGS1_k127_3673341_11	PFAM phosphoesterase, PA-phosphatase related	-	-	-	0.0000000000000006187	89.0
REGS1_k127_3673341_13	-	-	-	-	0.00004451	51.0
REGS1_k127_3673341_2	TIGRFAM drug resistance transporter, EmrB QacA subfamily	K03446	-	-	6.266e-199	633.0
REGS1_k127_3673341_3	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	K01950	-	6.3.5.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292	354.0
REGS1_k127_3673341_4	Biotin-lipoyl like	K07799	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217	328.0
REGS1_k127_3673341_5	O-methyltransferase activity	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762	330.0
REGS1_k127_3673341_6	TGS domain	K06944	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000005848	272.0
REGS1_k127_3673341_7	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	K01775	-	5.1.1.1	0.00000000000000000000000000000000000000000000000000000000000000002995	238.0
REGS1_k127_3673341_8	Oxidoreductase NAD-binding domain	-	-	-	0.000000000000000000000000000000000000000000000000005021	209.0
REGS1_k127_3673341_9	NUDIX hydrolase	-	-	-	0.0000000000000000000000000000000000000003004	160.0
REGS1_k127_368201_0	GTP-binding protein TypA	K06207	-	-	5.552e-270	844.0
REGS1_k127_368201_1	efflux transmembrane transporter activity	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452	566.0
REGS1_k127_368201_2	Dynamin family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799	533.0
REGS1_k127_368201_3	Conserved hypothetical protein (DUF2461)	-	-	-	0.00000000000000000000000000000000000000000000000001173	188.0
REGS1_k127_368201_4	EamA-like transporter family	-	-	-	0.0000000000000000000000000000000000000000000000008144	188.0
REGS1_k127_368201_5	DNA-templated transcription, initiation	K03088	-	-	0.0000000000000000000000000000000007509	135.0
REGS1_k127_368201_6	DinB family	-	-	-	0.000000000000000000000000000002811	136.0
REGS1_k127_368201_7	Fatty acid desaturase	-	-	-	0.00000000000024	81.0
REGS1_k127_368201_8	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	K02110	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	0.00004872	46.0
REGS1_k127_3728409_0	Involved in the tonB-independent uptake of proteins	K08884,K12132	-	2.7.11.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536	618.0
REGS1_k127_3728409_1	protease-associated PA domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205	320.0
REGS1_k127_3728409_2	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	K03564	-	1.11.1.15	0.00000000000000000000000000008768	118.0
REGS1_k127_3728409_3	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	K03564	-	1.11.1.15	0.00000000008636	72.0
REGS1_k127_3801387_0	Peptidase M14, carboxypeptidase A	-	-	-	4.917e-198	649.0
REGS1_k127_3801387_1	TIGRFAM Cell shape determining protein MreB Mrl	K03569	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492	556.0
REGS1_k127_3801387_10	Cell shape-determining protein MreC	K03570	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	0.0000000000000000000000000000000000002855	155.0
REGS1_k127_3801387_11	Putative adhesin	-	-	-	0.000000000000000000000000000003049	138.0
REGS1_k127_3801387_12	COG0350 Methylated DNA-protein cysteine methyltransferase	K00567	-	2.1.1.63	0.0000000000000002156	85.0
REGS1_k127_3801387_14	rod shape-determining protein MreD	K03571	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	0.00004587	56.0
REGS1_k127_3801387_15	Evidence 4 Homologs of previously reported genes of	-	-	-	0.000503	53.0
REGS1_k127_3801387_16	Putative zinc-finger	-	-	-	0.0007824	51.0
REGS1_k127_3801387_2	TIGRFAM ribonuclease, Rne Rng family	K08300,K08301	-	3.1.26.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235	505.0
REGS1_k127_3801387_3	Penicillin-binding protein, dimerisation domain	K05515	-	3.4.16.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377	501.0
REGS1_k127_3801387_4	peptidoglycan glycosyltransferase activity	K05837	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001516	294.0
REGS1_k127_3801387_5	Fungalysin/Thermolysin Propeptide Motif	K08603	-	3.4.24.27	0.000000000000000000000000000000000000000000000000000000000000000000000000000000454	287.0
REGS1_k127_3801387_6	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000006392	284.0
REGS1_k127_3801387_7	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	0.000000000000000000000000000000000000000000000000000000116	215.0
REGS1_k127_3801387_8	diguanylate cyclase	-	-	-	0.000000000000000000000000000000000000000000000005293	178.0
REGS1_k127_3801387_9	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.000000000000000000000000000000000000000005992	167.0
REGS1_k127_3843755_0	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	K01873	-	6.1.1.9	0.0	1124.0
REGS1_k127_3843755_1	Belongs to the class-I aminoacyl-tRNA synthetase family	K01887	-	6.1.1.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177	592.0
REGS1_k127_3843755_10	Tetratricopeptide repeat	-	-	-	0.00000000000000000000000003699	125.0
REGS1_k127_3843755_2	NfeD-like C-terminal, partner-binding	K07403	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076	359.0
REGS1_k127_3843755_3	prohibitin homologues	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543	338.0
REGS1_k127_3843755_4	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	K03525	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.1.33	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214	297.0
REGS1_k127_3843755_5	peptidase C26	K07010	-	-	0.0000000000000000000000000000000000000000000000002213	184.0
REGS1_k127_3843755_6	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	K03215	-	2.1.1.190	0.000000000000000000000000000000000000000000001326	181.0
REGS1_k127_3843755_7	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	K03524	-	6.3.4.15	0.0000000000000000000000000000000000000002974	166.0
REGS1_k127_3843755_8	TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B	K03753,K13818	-	2.7.7.77	0.00000000000000000000000000000005503	141.0
REGS1_k127_3843755_9	Quinolinate phosphoribosyl transferase, N-terminal domain	K00767	-	2.4.2.19	0.0000000000000000000000000000009034	142.0
REGS1_k127_3844799_0	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	-	8.102e-256	808.0
REGS1_k127_3844799_1	Carbohydrate family 9 binding domain-like	-	-	-	1.227e-214	687.0
REGS1_k127_3844799_10	-	-	-	-	0.000000000000000000001022	97.0
REGS1_k127_3844799_11	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	K03088	-	-	0.000000000003718	72.0
REGS1_k127_3844799_12	-	-	-	-	0.00000003997	65.0
REGS1_k127_3844799_13	TIGRFAM MoaD family protein	K03636	-	-	0.000001881	57.0
REGS1_k127_3844799_2	efflux transmembrane transporter activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956	604.0
REGS1_k127_3844799_3	Gamma-glutamyltranspeptidase	K00681	-	2.3.2.2,3.4.19.13	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396	573.0
REGS1_k127_3844799_4	Amidohydrolase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284	496.0
REGS1_k127_3844799_5	Pirin C-terminal cupin domain	K06911	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486	486.0
REGS1_k127_3844799_6	COG2939 Carboxypeptidase C (cathepsin A)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755	466.0
REGS1_k127_3844799_7	Ornithine cyclodeaminase/mu-crystallin family	K01750	-	4.3.1.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003974	310.0
REGS1_k127_3844799_8	Proline racemase	K01777	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0071704,GO:1901564	5.1.1.4	0.0000000000000000000000000000000000000000000000000000001831	219.0
REGS1_k127_3844799_9	-O-antigen	K02847,K18814	-	-	0.0000000000000000000000000005352	129.0
REGS1_k127_3879326_0	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	K00164	-	1.2.4.2	2.391e-214	679.0
REGS1_k127_3879326_1	2-oxoglutarate dehydrogenase N-terminus	K00164	-	1.2.4.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629	353.0
REGS1_k127_3879326_2	Calcineurin-like phosphoesterase superfamily domain	K07095	-	-	0.000000000000000000000000000000000000000000000000000000001061	204.0
REGS1_k127_3879326_3	Protein of unknown function (DUF1572)	-	-	-	0.000000000000000000000000000000000000000000000000000000357	199.0
REGS1_k127_3879326_4	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	K00627,K00658,K09699	-	2.3.1.12,2.3.1.168,2.3.1.61	0.000000000000000000000000000005532	129.0
REGS1_k127_3886117_0	Protein of unknown function (DUF1343)	-	-	-	1.472e-243	777.0
REGS1_k127_3886117_1	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	K07516	-	1.1.1.35	4.062e-236	763.0
REGS1_k127_3886117_10	hydrolase of the alpha beta	K07018	-	-	0.00000000000000000000000000000000000000005958	166.0
REGS1_k127_3886117_11	Protein of unknown function (DUF420)	K08976	-	-	0.00000000000000000000000000000000000000522	160.0
REGS1_k127_3886117_12	Response regulator receiver	K18967	-	2.7.7.65	0.000000000000000000000000000001286	137.0
REGS1_k127_3886117_13	-	-	-	-	0.00000000000000000006812	103.0
REGS1_k127_3886117_14	transcriptional	K21600	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	0.000000000000000006448	89.0
REGS1_k127_3886117_15	transcriptional	K21600	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	0.00000000000000002458	87.0
REGS1_k127_3886117_16	Alpha beta hydrolase	-	-	-	0.000000000003662	79.0
REGS1_k127_3886117_17	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	0.00009747	47.0
REGS1_k127_3886117_2	Thiolase, C-terminal domain	K00632	-	2.3.1.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163	518.0
REGS1_k127_3886117_3	Carboxypeptidase regulatory-like domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406	453.0
REGS1_k127_3886117_4	AAA domain, putative AbiEii toxin, Type IV TA system	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586	370.0
REGS1_k127_3886117_5	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	K02257	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	0.00000000000000000000000000000000000000000000000000000000000000000000000000000008159	276.0
REGS1_k127_3886117_6	PFAM peptidase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000127	252.0
REGS1_k127_3886117_7	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000000000000000000005422	243.0
REGS1_k127_3886117_8	PFAM blue (type 1) copper domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000002277	221.0
REGS1_k127_3886117_9	Bacterial regulatory proteins, tetR family	K13770	-	-	0.00000000000000000000000000000000000000000006038	167.0
REGS1_k127_3972224_0	DEAD DEAH box helicase	K03724	-	-	0.0	1375.0
REGS1_k127_3972224_1	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	5.269e-211	684.0
REGS1_k127_3972224_10	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	0.0000000006282	72.0
REGS1_k127_3972224_2	Las17-binding protein actin regulator	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000003216	262.0
REGS1_k127_3972224_3	MobA-like NTP transferase domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001911	266.0
REGS1_k127_3972224_4	Belongs to the GHMP kinase family. GalK subfamily	K00849	-	2.7.1.6	0.0000000000000000000000000000000000000000000000000000000000006864	229.0
REGS1_k127_3972224_5	Peptidase family M48	-	-	-	0.000000000000000000000000000000000000000000000000000000001872	220.0
REGS1_k127_3972224_6	Cyclic nucleotide-monophosphate binding domain	-	-	-	0.00000000000000000000000000000000000000545	147.0
REGS1_k127_3972224_7	-	-	-	-	0.000000000000000000000004912	104.0
REGS1_k127_3972224_8	-	-	-	-	0.0000000000005482	72.0
REGS1_k127_3972224_9	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	-	0.00000000000271	74.0
REGS1_k127_4032154_0	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	0.0	1096.0
REGS1_k127_4032154_1	Beta-L-arabinofuranosidase, GH127	K09955	-	-	2.486e-246	784.0
REGS1_k127_4032154_2	Berberine and berberine like	-	-	-	6.005e-199	629.0
REGS1_k127_4032154_3	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948	387.0
REGS1_k127_4032154_4	FKBP-type peptidyl-prolyl cis-trans isomerase	K01802,K03772	-	5.2.1.8	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644	298.0
REGS1_k127_4032154_5	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	0.00000000000000000000000000000000000000000000003142	176.0
REGS1_k127_4032154_6	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	K03307	-	-	0.00000000000000000000000000000000000000000000006645	186.0
REGS1_k127_4032154_7	-	-	-	-	0.000000000000000000000000000000000001393	148.0
REGS1_k127_4032154_8	response regulator	-	-	-	0.0000000000005964	75.0
REGS1_k127_4032154_9	cell adhesion involved in biofilm formation	-	-	-	0.00005598	54.0
REGS1_k127_4053814_0	Amidohydrolase family	-	-	-	1.21e-243	764.0
REGS1_k127_4053814_1	Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type	K11381	-	1.2.4.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058	386.0
REGS1_k127_4053814_10	ATP-dependent helicase	K03579	-	3.6.4.13	0.00000000000000000000000000000000000000000000000000000001162	217.0
REGS1_k127_4053814_11	OmpA family	-	-	-	0.0000000000000000000000000000000000000000000000000000002308	206.0
REGS1_k127_4053814_12	Glycosyltransferase Family 4	-	-	-	0.0000000000000000000000000000000000000000000000000001132	204.0
REGS1_k127_4053814_13	Glycosyl transferases group 1	-	-	-	0.0000000000000000000000000000000000000000000000000002452	209.0
REGS1_k127_4053814_14	Bacterial sugar transferase	-	-	-	0.000000000000000000000000000000000000000000000000004234	189.0
REGS1_k127_4053814_15	geranylgeranyl reductase activity	K06444,K17830	-	1.3.1.101,1.3.7.11,5.5.1.18	0.000000000000000000000000000000000000000000000000009711	195.0
REGS1_k127_4053814_16	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	0.0000000000000000000000000000000000000000000000001584	196.0
REGS1_k127_4053814_17	SLBB domain	K01991	-	-	0.0000000000000000000000000000000000000000000000001588	186.0
REGS1_k127_4053814_18	PFAM glycosyl transferase group 1	-	-	-	0.000000000000000000000000000000000000000000000003348	189.0
REGS1_k127_4053814_19	methyltransferase	-	-	-	0.000000000000000000000000000000000000000000000109	177.0
REGS1_k127_4053814_2	G-rich domain on putative tyrosine kinase	K08252,K16554	-	2.7.10.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722	355.0
REGS1_k127_4053814_20	Glycosyltransferase Family 4	-	-	-	0.0000000000000000000000000000000000000000000001607	184.0
REGS1_k127_4053814_21	Methyltransferase domain	-	-	-	0.000000000000000000000000000000000000000000001348	175.0
REGS1_k127_4053814_22	Uncharacterised nucleotidyltransferase	-	-	-	0.000000000000000000000000000000000000000000001634	179.0
REGS1_k127_4053814_23	Bacterial membrane protein YfhO	-	-	-	0.000000000000000000000000000000000000002369	169.0
REGS1_k127_4053814_24	response regulator	K13599	-	-	0.00000000000000000000000000000000000009072	156.0
REGS1_k127_4053814_25	ATP-dependent helicase	K03579	-	3.6.4.13	0.00000000000000000000000000000000001067	145.0
REGS1_k127_4053814_26	O-Antigen ligase	K02847	-	-	0.00000000000000000000000000000000005319	151.0
REGS1_k127_4053814_27	Polysaccharide biosynthesis protein	-	-	-	0.000000000000000000000000003852	126.0
REGS1_k127_4053814_28	O-antigen ligase like membrane protein	-	-	-	0.00000000000000004797	96.0
REGS1_k127_4053814_3	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419	318.0
REGS1_k127_4053814_30	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	K01953	-	6.3.5.4	0.00000000001106	66.0
REGS1_k127_4053814_31	Glycosyl transferase 4-like domain	-	-	-	0.0000000002246	72.0
REGS1_k127_4053814_33	Transglutaminase-like superfamily	-	-	-	0.000001365	58.0
REGS1_k127_4053814_4	Glycosyl transferases group 1	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000009377	262.0
REGS1_k127_4053814_5	PFAM Asparaginase	K01424	-	3.5.1.1	0.00000000000000000000000000000000000000000000000000000000000000000005267	237.0
REGS1_k127_4053814_6	protein methyltransferase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000003876	236.0
REGS1_k127_4053814_7	Glycosyltransferase like family 2	K07011	-	-	0.0000000000000000000000000000000000000000000000000000000000000006587	235.0
REGS1_k127_4053814_8	transferase activity, transferring glycosyl groups	K00713,K03280	-	2.4.1.56	0.0000000000000000000000000000000000000000000000000000000000000009228	235.0
REGS1_k127_4053814_9	-	-	-	-	0.000000000000000000000000000000000000000000000000000000000006366	215.0
REGS1_k127_4112744_0	ATP-dependent Clp protease ATP-binding subunit ClpA	K03694	-	-	3.082e-251	797.0
REGS1_k127_4112744_1	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	K01761	-	4.4.1.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725	568.0
REGS1_k127_4112744_2	MacB-like periplasmic core domain	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803	562.0
REGS1_k127_4112744_3	Metallo-beta-lactamase superfamily	K17837	-	3.5.2.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000299	287.0
REGS1_k127_4112744_4	ABC transporter	K02003	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001082	246.0
REGS1_k127_4112744_5	Outer membrane lipoprotein-sorting protein	-	-	-	0.000000000000000000000000000000000000000000007952	173.0
REGS1_k127_4112744_6	HAD-hyrolase-like	K01091	-	3.1.3.18	0.000000000000000000000000000000000000000001196	170.0
REGS1_k127_4112744_7	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	K06891	-	-	0.0000000000000000000000000008741	117.0
REGS1_k127_4112744_8	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	K03687	-	-	0.0000000000000000003293	95.0
REGS1_k127_4112744_9	-	-	-	-	0.00000000266	70.0
REGS1_k127_4120640_0	Mur ligase middle domain	K02558	-	6.3.2.45	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758	447.0
REGS1_k127_4120640_1	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	K00790	-	2.5.1.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948	336.0
REGS1_k127_4120640_10	-	-	-	-	0.000000000000000000000000006816	120.0
REGS1_k127_4120640_11	Helix-turn-helix domain	-	-	-	0.0002477	48.0
REGS1_k127_4120640_12	Rhodanese Homology Domain	-	-	-	0.0005459	48.0
REGS1_k127_4120640_2	Type ii and iii secretion system protein	K02453	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933	334.0
REGS1_k127_4120640_3	Glycosyl hydrolase family 3 N terminal domain	K01207	-	3.2.1.52	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001015	300.0
REGS1_k127_4120640_4	GHMP kinases C terminal	K07031	-	2.7.1.168	0.00000000000000000000000000000000000000000000000000000000000000000000000000002093	281.0
REGS1_k127_4120640_5	Carboxyltransferase domain, subdomain A and B	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000002207	265.0
REGS1_k127_4120640_6	LD-carboxypeptidase	K01297	-	3.4.17.13	0.00000000000000000000000000000000000000000000000000000000000004422	226.0
REGS1_k127_4120640_7	Allophanate hydrolase, subunit 1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000004078	225.0
REGS1_k127_4120640_8	Cell wall formation	K00075	-	1.3.1.98	0.000000000000000000000000000000000000000000000000000001119	205.0
REGS1_k127_4120640_9	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	K03634	-	-	0.00000000000000000000000000001299	126.0
REGS1_k127_4180955_0	radical SAM domain protein	K22318	-	-	1.252e-237	751.0
REGS1_k127_4180955_1	Malic enzyme, NAD binding domain	K00027,K00029	-	1.1.1.38,1.1.1.40	6.376e-216	682.0
REGS1_k127_4180955_2	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.00000000000000000000000000002413	124.0
REGS1_k127_4180955_3	Outer membrane efflux protein	-	-	-	0.0000000000000044	82.0
REGS1_k127_4180955_4	Domain of unknown function (DUF4349)	-	-	-	0.00009244	50.0
REGS1_k127_423512_0	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	K03596	-	-	2.04e-290	901.0
REGS1_k127_423512_1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	K03086	-	-	2.251e-200	639.0
REGS1_k127_423512_10	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	K03531	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248	416.0
REGS1_k127_423512_11	SMART PUA domain containing protein	K06969	-	2.1.1.191	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003	364.0
REGS1_k127_423512_12	Belongs to the SEDS family	K03588	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989	354.0
REGS1_k127_423512_13	Belongs to the metallo-dependent hydrolases superfamily. HutI family	K01468	-	3.5.2.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085	361.0
REGS1_k127_423512_14	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	K02316	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014	353.0
REGS1_k127_423512_15	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	K02563	-	2.4.1.227	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869	314.0
REGS1_k127_423512_16	(AIR) carboxylase	K06898	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000008703	294.0
REGS1_k127_423512_17	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	K01925	-	6.3.2.9	0.000000000000000000000000000000000000000000000000000000000000000000000002595	255.0
REGS1_k127_423512_18	PFAM D12 class N6 adenine-specific DNA methyltransferase	K06223	-	2.1.1.72	0.000000000000000000000000000000000000000000000000000000000000000003039	238.0
REGS1_k127_423512_19	Belongs to the peptidase S26 family	K03100	-	3.4.21.89	0.0000000000000000000000000000000000000000000000000000000000000033	224.0
REGS1_k127_423512_2	Glycosyl transferase family 21	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439	598.0
REGS1_k127_423512_20	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	K06997	-	-	0.00000000000000000000000000000000000000000000000000000000001026	218.0
REGS1_k127_423512_21	C4-type zinc ribbon domain	K07164	-	-	0.000000000000000000000000000000000000000002079	165.0
REGS1_k127_423512_22	Belongs to the multicopper oxidase YfiH RL5 family	K05810	-	-	0.0000000000000000000000000000000000000002219	163.0
REGS1_k127_423512_23	Ribose 5-phosphate isomerase	K01808	-	5.3.1.6	0.000000000000000000000000000000000000002228	166.0
REGS1_k127_423512_24	Formiminotransferase-cyclodeaminase	-	-	-	0.000000000000000000000000000000000128	149.0
REGS1_k127_423512_25	Reverse transcriptase-like	K03469	-	3.1.26.4	0.0000000000000000000000000000000006478	142.0
REGS1_k127_423512_26	DUF167	K09131	-	-	0.00000000000000000006958	97.0
REGS1_k127_423512_27	PFAM DivIVA family protein	K04074	-	-	0.000000000000000002414	93.0
REGS1_k127_423512_28	Tetratricopeptide repeat	-	-	-	0.000000000000009172	85.0
REGS1_k127_423512_29	Cell division protein FtsQ	K03589	-	-	0.00000000000007547	81.0
REGS1_k127_423512_3	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	K00600	-	2.1.2.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226	584.0
REGS1_k127_423512_4	HELICc2	K03722	-	3.6.4.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624	555.0
REGS1_k127_423512_5	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	K03590	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985	498.0
REGS1_k127_423512_6	Belongs to the MurCDEF family	K01924	-	6.3.2.8	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314	489.0
REGS1_k127_423512_7	Citrate synthase, C-terminal domain	K01647	-	2.3.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069	446.0
REGS1_k127_423512_8	Elongator protein 3, MiaB family, Radical SAM	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047	450.0
REGS1_k127_423512_9	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	K07456	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064	441.0
REGS1_k127_4316467_0	GTP binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675	505.0
REGS1_k127_4316467_1	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936	500.0
REGS1_k127_4316467_2	NMT1-like family	K07080	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000002159	262.0
REGS1_k127_4316467_3	Belongs to the enoyl-CoA hydratase isomerase family	K16880	-	-	0.00000000000000000000000000000000000001626	156.0
REGS1_k127_4316467_4	Glycosyl Hydrolase Family 88	K18581	-	3.2.1.180	0.00000002535	55.0
REGS1_k127_4367135_0	cellulose binding	-	-	-	2.801e-303	962.0
REGS1_k127_4367135_1	Polysulphide reductase, NrfD	K00185	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579	551.0
REGS1_k127_4367135_10	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	K03282	-	-	0.000000000000000000000000000000000000009012	149.0
REGS1_k127_4367135_11	Endoribonuclease L-PSP	-	-	-	0.00000000000000000085	93.0
REGS1_k127_4367135_12	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	0.000000000008598	71.0
REGS1_k127_4367135_13	Protein of unknown function (DUF2891)	-	-	-	0.000000005706	59.0
REGS1_k127_4367135_14	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	0.000000006805	69.0
REGS1_k127_4367135_15	Response regulator receiver	K07670	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	0.00000007808	66.0
REGS1_k127_4367135_2	peptidase activity	K01266	-	3.4.11.19	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402	486.0
REGS1_k127_4367135_3	4Fe-4S dicluster domain	K00184	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764	429.0
REGS1_k127_4367135_4	Cystathionine beta-synthase	K01697	-	4.2.1.22	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886	349.0
REGS1_k127_4367135_5	Integral membrane protein TerC family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512	323.0
REGS1_k127_4367135_6	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000006735	232.0
REGS1_k127_4367135_7	Cytochrome c	-	-	-	0.0000000000000000000000000000000000000000000000000000004879	204.0
REGS1_k127_4367135_8	Putative stress-induced transcription regulator	-	-	-	0.000000000000000000000000000000000000000000000000005995	188.0
REGS1_k127_4367135_9	histidine kinase HAMP region domain protein	K02482	-	2.7.13.3	0.000000000000000000000000000000000000000004004	177.0
REGS1_k127_439553_0	Por secretion system C-terminal sorting domain-containing protein	-	-	-	0.0	1025.0
REGS1_k127_439553_1	SPTR Glycosyl hydrolase, BNR repeat-containing protein	-	-	-	6.699e-294	923.0
REGS1_k127_439553_2	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329	443.0
REGS1_k127_439553_3	SNARE associated Golgi protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000004576	207.0
REGS1_k127_439553_4	RF-1 domain	K15034	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	0.00000000000000000000008042	102.0
REGS1_k127_439553_5	RF-1 domain	K15034	-	-	0.0002207	45.0
REGS1_k127_444474_0	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	K01872	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	1.36e-266	850.0
REGS1_k127_444474_1	Type II/IV secretion system protein	K02669	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641	502.0
REGS1_k127_444474_10	Modulates RecA activity	K03565	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000008468	65.0
REGS1_k127_444474_2	Serine aminopeptidase, S33	K00433	-	1.11.1.10	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242	454.0
REGS1_k127_444474_3	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	K00826	-	2.6.1.42	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428	407.0
REGS1_k127_444474_4	Cupin domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001056	258.0
REGS1_k127_444474_5	Tellurite resistance protein TerB	-	-	-	0.00000000000000000000000000000000000000000000000004389	188.0
REGS1_k127_444474_6	Transglycosylase SLT domain	K01185	-	3.2.1.17	0.00000000000000000000000000000000000000003082	164.0
REGS1_k127_444474_7	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog	K04762	-	-	0.00000000000000005709	85.0
REGS1_k127_444474_8	Ribosomal protein S20	K02968	-	-	0.0000000000107	69.0
REGS1_k127_444474_9	TIGRFAM DNA polymerase III, delta subunit	K02340	-	2.7.7.7	0.000000002502	68.0
REGS1_k127_444788_0	Amp-dependent synthetase and ligase	K00797,K01897	-	2.5.1.16,6.2.1.3	0.0	1146.0
REGS1_k127_444788_1	Aconitase family (aconitate hydratase)	K01703,K01704,K01705	-	4.2.1.33,4.2.1.35,4.2.1.36	1.998e-273	858.0
REGS1_k127_444788_2	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193	415.0
REGS1_k127_444788_3	Domain of unknown function (DUF4010)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000003479	269.0
REGS1_k127_444788_4	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	K01845	-	5.4.3.8	0.000000000000000000000000000000000000000003263	158.0
REGS1_k127_4503348_0	Protein of unknown function, DUF255	K06888	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573	475.0
REGS1_k127_4503348_1	two component, sigma54 specific, transcriptional regulator, Fis family	K02481,K07713	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257	412.0
REGS1_k127_4503348_10	-	-	-	-	0.0003827	53.0
REGS1_k127_4503348_2	two component, sigma54 specific, transcriptional regulator, Fis family	K02667	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338	313.0
REGS1_k127_4503348_3	pfam abc	K01990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001124	286.0
REGS1_k127_4503348_4	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	K00573	-	2.1.1.77	0.000000000000000000000000000000000000000000000000000000000000000003194	233.0
REGS1_k127_4503348_5	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	0.000000000000000000000000000000000000000000000000000131	206.0
REGS1_k127_4503348_6	DJ-1/PfpI family	K05520	-	3.5.1.124	0.00000000000000000000000000000000000000000000056	175.0
REGS1_k127_4503348_7	ribonuclease BN	K07058	-	-	0.0000000000000000000000002009	118.0
REGS1_k127_4503348_8	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.0000000002274	72.0
REGS1_k127_4503348_9	YtxH-like protein	-	-	-	0.0001691	51.0
REGS1_k127_4561500_0	Transketolase, pyrimidine binding domain	K00615	-	2.2.1.1	7.969e-230	729.0
REGS1_k127_4561500_1	Gamma-glutamyltranspeptidase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304	542.0
REGS1_k127_4561500_10	AAA ATPase central domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000001925	192.0
REGS1_k127_4561500_11	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	K00335,K18331,K22339	-	1.12.1.3,1.17.1.11,1.6.5.3	0.000000000000000000008986	109.0
REGS1_k127_4561500_12	Belongs to the GPAT DAPAT family	K00631	GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.15	0.0000000000000000005211	99.0
REGS1_k127_4561500_13	phosphoesterase, PA-phosphatase related	-	-	-	0.00000000000377	79.0
REGS1_k127_4561500_14	NmrA-like family	-	-	-	0.0000000324	57.0
REGS1_k127_4561500_2	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	K00974	-	2.7.7.72	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998	402.0
REGS1_k127_4561500_3	succinyl-diaminopimelate desuccinylase activity	K01438	-	3.5.1.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429	357.0
REGS1_k127_4561500_4	Proline dehydrogenase	K00318	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005144	297.0
REGS1_k127_4561500_5	O-methyltransferase, family 2	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000004449	295.0
REGS1_k127_4561500_6	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	K01754	-	4.3.1.19	0.000000000000000000000000000000000000000000000000000000000000000000000000001038	276.0
REGS1_k127_4561500_7	Dienelactone hydrolase family	K01061	-	3.1.1.45	0.00000000000000000000000000000000000000000000000000000000000000000000000000838	266.0
REGS1_k127_4561500_8	lyase activity	K03301	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001542	282.0
REGS1_k127_4561500_9	TLC ATP/ADP transporter	K03301	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000004698	271.0
REGS1_k127_4595805_0	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289	452.0
REGS1_k127_4595805_1	Molybdopterin oxidoreductase Fe4S4 domain	K08352	-	1.8.5.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125	353.0
REGS1_k127_4595805_2	Belongs to the GSP D family	K02280	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824	316.0
REGS1_k127_4595805_3	DNA modification	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003413	321.0
REGS1_k127_4595805_4	PFAM helicase domain protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000006905	239.0
REGS1_k127_4595805_5	PFAM SAF domain	K02279	-	-	0.0000000000000000000000000000000000000000000001336	178.0
REGS1_k127_4595805_6	Type IV leader peptidase family	K02278	-	3.4.23.43	0.0000000000002743	79.0
REGS1_k127_4595805_7	TadE-like protein	-	-	-	0.0000000001636	69.0
REGS1_k127_4595805_8	PFAM Flp Fap pilin component	K02651	-	-	0.000007952	49.0
REGS1_k127_4595805_9	PFAM Flp Fap pilin component	K02651	-	-	0.000611	46.0
REGS1_k127_46147_0	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	K02470,K02622	-	5.99.1.3	1.525e-280	874.0
REGS1_k127_46147_1	PFAM amidohydrolase	-	-	-	5.863e-231	737.0
REGS1_k127_46147_10	Belongs to the 'phage' integrase family	-	-	-	0.000005631	55.0
REGS1_k127_46147_2	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	K00658	-	2.3.1.61	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599	387.0
REGS1_k127_46147_3	Glycosyltransferase like family 2	-	-	-	0.000000000000000000000000000000000000000000000000000000000000005981	225.0
REGS1_k127_46147_4	Methyl-transferase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000009521	224.0
REGS1_k127_46147_5	GAF domain	K08968	-	1.8.4.14	0.0000000000000000000000000000000000000000000000003176	181.0
REGS1_k127_46147_6	hopanoid biosynthesis associated protein HpnK	-	-	-	0.0000000000000000000000000000000000000000000009346	189.0
REGS1_k127_46147_7	PFAM CoA-binding domain protein	K06929	-	-	0.0000000000000000000000000000000000000000000009589	184.0
REGS1_k127_46147_8	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	0.0000000000000000009481	101.0
REGS1_k127_46147_9	Methyltransferase small domain	-	-	-	0.00000000000000004728	93.0
REGS1_k127_4638881_0	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	K01885	-	6.1.1.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829	486.0
REGS1_k127_4638881_1	Carboxypeptidase regulatory-like domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000141	269.0
REGS1_k127_4638881_2	Belongs to the peptidase S8 family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000139	218.0
REGS1_k127_4737269_0	Domain of unknown function (DUF5117)	-	-	-	1e-323	1013.0
REGS1_k127_4737269_1	Peptidase family M1 domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404	528.0
REGS1_k127_4737269_2	Family of unknown function (DUF1028)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854	350.0
REGS1_k127_4737269_3	DEAD/H associated	K03724	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000003184	258.0
REGS1_k127_4737269_4	Iron-storage protein	K02217	-	1.16.3.2	0.000000000000000000000000000000000000002586	155.0
REGS1_k127_4737269_5	PFAM RNP-1 like RNA-binding protein	-	-	-	0.0000000000000000000000000000255	122.0
REGS1_k127_4762272_0	Belongs to the glycosyl hydrolase 31 family	K01187	-	3.2.1.20	4.119e-317	997.0
REGS1_k127_4762272_1	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	K11102	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482	427.0
REGS1_k127_4762272_2	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	K00325	-	1.6.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637	368.0
REGS1_k127_4762272_3	-	-	-	-	0.00000000000000000000000000000000000000000000000005898	195.0
REGS1_k127_4762272_4	4Fe-4S binding domain	-	-	-	0.000000000000000000000000000000386	126.0
REGS1_k127_4762272_5	4TM region of pyridine nucleotide transhydrogenase, mitoch	K00324	-	1.6.1.2	0.000000000000000000000000002218	115.0
REGS1_k127_4762272_6	Methionine biosynthesis protein MetW	-	-	-	0.000000000000000007317	93.0
REGS1_k127_4775159_0	Myo-inositol-1-phosphate synthase	K01858	-	5.5.1.4	1.116e-202	638.0
REGS1_k127_4775159_1	Enoyl-(Acyl carrier protein) reductase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000004703	262.0
REGS1_k127_4775159_10	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	0.000000000006319	74.0
REGS1_k127_4775159_2	SMART AAA ATPase	K02450	-	-	0.0000000000000000000000000000000000000000000000000000000000000000004244	259.0
REGS1_k127_4775159_3	ZIP Zinc transporter	K16267	-	-	0.00000000000000000000000000000000000000000000000000000000000000001488	233.0
REGS1_k127_4775159_4	Toxic component of a toxin-antitoxin (TA) module	K07171	-	-	0.00000000000000000000000000000000000002642	148.0
REGS1_k127_4775159_5	Gram-negative bacterial TonB protein C-terminal	-	-	-	0.00000000000000000000000000000000000302	152.0
REGS1_k127_4775159_6	von Willebrand factor (vWF) type A domain	K07114	-	-	0.00000000000000000000000000000000002087	150.0
REGS1_k127_4775159_7	-	-	-	-	0.000000000000000000000000006942	116.0
REGS1_k127_4775159_8	Transcriptional regulator	-	-	-	0.0000000000000001426	81.0
REGS1_k127_4775159_9	Type IVB pilus formation outer membrane protein	-	-	-	0.000000000000002368	89.0
REGS1_k127_4887558_0	ABC transporter	K03701	-	-	0.0	1182.0
REGS1_k127_4887558_1	amino acid	K03294	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536	460.0
REGS1_k127_4887558_10	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	K03814	-	2.4.1.129	0.00000000000000000000000000000000000000000000000000000001121	212.0
REGS1_k127_4887558_11	RNA polymerase sigma factor	K03088	-	-	0.00000000000000000000000000000000000000000001936	169.0
REGS1_k127_4887558_12	Phosphoribosyl transferase domain	-	-	-	0.000000000000000000000000000000000000006354	158.0
REGS1_k127_4887558_13	NlpC P60 family protein	-	-	-	0.00000000000000000000000000007845	123.0
REGS1_k127_4887558_14	thymidylate kinase	K00943	-	2.7.4.9	0.00000000000000000000000001812	118.0
REGS1_k127_4887558_15	Sigma-54 factor interaction domain-containing protein	K07713	-	-	0.0000000000000000308	84.0
REGS1_k127_4887558_16	-	-	-	-	0.0000000000001539	83.0
REGS1_k127_4887558_17	STAS domain	K04749	-	-	0.000000000004497	70.0
REGS1_k127_4887558_2	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	K01586	-	4.1.1.20	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059	375.0
REGS1_k127_4887558_3	aminotransferase	K00830	-	2.6.1.44,2.6.1.45,2.6.1.51	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237	369.0
REGS1_k127_4887558_4	CoA-transferase family III	K01796	-	5.1.99.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992	322.0
REGS1_k127_4887558_5	Peptidase family M48	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697	308.0
REGS1_k127_4887558_6	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	K02535	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002341	290.0
REGS1_k127_4887558_7	amine dehydrogenase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000002647	275.0
REGS1_k127_4887558_8	HNH nucleases	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001144	252.0
REGS1_k127_4887558_9	Belongs to the DapA family	K01714,K22397	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575	4.1.2.28,4.3.3.7	0.00000000000000000000000000000000000000000000000000000000000000000003595	244.0
REGS1_k127_4909903_0	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	K00525	-	1.17.4.1	0.0	1244.0
REGS1_k127_4909903_1	Domain of unknown function (DUF1998)	K06877	-	-	5.194e-255	818.0
REGS1_k127_4909903_2	Sodium:alanine symporter family	K03310	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358	571.0
REGS1_k127_4909903_3	Enoyl-(Acyl carrier protein) reductase	K00059	-	1.1.1.100	0.00000000000000000000000000000000000000000000000000000000000000000000000000004979	267.0
REGS1_k127_4909903_4	CGGC	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000214	248.0
REGS1_k127_4909903_5	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000008753	249.0
REGS1_k127_4909903_6	PFAM alpha beta hydrolase fold	-	-	-	0.00000000000000000000000000000000000000000000000000000000129	216.0
REGS1_k127_4909903_7	Exonuclease	K07502	-	-	0.0000000000000000000000000000000000000000000000000000003899	211.0
REGS1_k127_4909903_8	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	0.000000000000000000000000000000000000124	145.0
REGS1_k127_4909903_9	Binds the 23S rRNA	K02909	-	-	0.0000000000000000000000000008355	115.0
REGS1_k127_4991128_0	lysine biosynthetic process via aminoadipic acid	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586	532.0
REGS1_k127_4991128_1	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000004089	242.0
REGS1_k127_4991128_3	methionine synthase	K00548	-	2.1.1.13	0.0000000000000000000000000000000000000000002493	175.0
REGS1_k127_4991128_4	Rieske [2Fe-2S] domain	-	-	-	0.00000000000000000000000000000000000000006599	153.0
REGS1_k127_4991128_5	hydrolase of the alpha beta-hydrolase fold	K07020	-	-	0.0000000000000000000000000000000000000005736	158.0
REGS1_k127_4991128_6	Transglycosylase SLT domain	K08309	-	-	0.0000000000000000000000000000000002537	153.0
REGS1_k127_4991128_7	SnoaL-like domain	-	-	-	0.000000000000437	76.0
REGS1_k127_4991128_8	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	0.000003411	59.0
REGS1_k127_5045698_0	secretion system protein	K02283	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982	558.0
REGS1_k127_5045698_1	ATPase family associated with various cellular activities (AAA)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738	421.0
REGS1_k127_5045698_10	Smr domain	-	-	-	0.00000000000000000002079	98.0
REGS1_k127_5045698_11	Bacterial DNA-binding protein	K03530	-	-	0.0000000000000000001353	91.0
REGS1_k127_5045698_2	type II secretion system	K12511	-	-	0.000000000000000000000000000000000000000000000000000000000000007357	228.0
REGS1_k127_5045698_3	type II secretion system protein	K12510	-	-	0.0000000000000000000000000000000000000000000000000000000008081	228.0
REGS1_k127_5045698_4	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	K09457	-	1.7.1.13	0.000000000000000000000000000000000000000000001571	172.0
REGS1_k127_5045698_5	AAA domain	K02282	-	-	0.000000000000000000000000000000000000000003188	170.0
REGS1_k127_5045698_6	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.00000000000000000000000000000000000001672	164.0
REGS1_k127_5045698_7	Putative Flp pilus-assembly TadE/G-like	-	-	-	0.00000000000000000000000000000000000389	151.0
REGS1_k127_5045698_8	ABC transporter substrate-binding protein	K02035	-	-	0.000000000000000000000000008296	124.0
REGS1_k127_5045698_9	Phospholipid methyltransferase	-	-	-	0.00000000000000000000000069	121.0
REGS1_k127_5080452_0	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	K03296	-	-	4.137e-296	942.0
REGS1_k127_5080452_1	ABC transporter	K02003	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319	309.0
REGS1_k127_5080452_2	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K02005	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002191	296.0
REGS1_k127_5080452_3	Efflux ABC transporter permease protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000002359	271.0
REGS1_k127_5096915_0	xanthine dehydrogenase activity	-	-	-	4.715e-308	960.0
REGS1_k127_5096915_1	PFAM Zinc carboxypeptidase	-	-	-	1.158e-213	691.0
REGS1_k127_5096915_2	MacB-like periplasmic core domain	K02004	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216	327.0
REGS1_k127_5096915_3	CO dehydrogenase flavoprotein C-terminal domain	K13479	-	1.17.1.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795	321.0
REGS1_k127_5096915_4	MacB-like periplasmic core domain	K02004	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000007814	267.0
REGS1_k127_5096915_5	Efflux transporter, RND family, MFP subunit	K02005	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000001062	263.0
REGS1_k127_5096915_6	2 iron, 2 sulfur cluster binding	K03518,K07302,K13483	-	1.2.5.3,1.3.99.16	0.000000000000000000000000000000000000000000000000000006361	193.0
REGS1_k127_5096915_7	PFAM amidohydrolase	K01464	-	3.5.2.2	0.000000000000000000000000000000000000000000000008899	174.0
REGS1_k127_5115608_0	Enoyl-CoA hydratase/isomerase	K15513	-	4.1.2.44	7.482e-226	712.0
REGS1_k127_5115608_1	benzoyl-CoA oxygenase	K15512	-	1.14.13.208	1.536e-205	667.0
REGS1_k127_5115608_2	PFAM Aminotransferase class I and II	K05825	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123	595.0
REGS1_k127_5115608_3	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	K03644	-	2.8.1.8	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456	394.0
REGS1_k127_5115608_4	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454	394.0
REGS1_k127_5115608_5	Belongs to the UPF0173 family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004138	286.0
REGS1_k127_5115608_6	UreE urease accessory protein, C-terminal domain	K21929	-	3.2.2.27	0.000000000000000000000000000000000000000000000000000000000000000000000456	248.0
REGS1_k127_5115608_7	Belongs to the aldehyde dehydrogenase family	K00128,K00146	-	1.2.1.3,1.2.1.39	0.0000000000000000000000000000000000000000000000006844	178.0
REGS1_k127_5115608_8	Bacterial regulatory proteins, tetR family	-	-	-	0.00000000000000000000000000000000000003761	150.0
REGS1_k127_5125428_0	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	6.667e-200	636.0
REGS1_k127_5125428_1	Permease family	K06901	GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579	486.0
REGS1_k127_5125428_2	-	-	-	-	0.00000000000000000000000000000000000000000000001289	181.0
REGS1_k127_5125428_3	Winged helix DNA-binding domain	-	-	-	0.000000000000000000000000000000000000000000001276	168.0
REGS1_k127_5125428_4	COG0491 Zn-dependent hydrolases, including glyoxylases	K01069	-	3.1.2.6	0.0000000000000000000000000000000000000000000247	177.0
REGS1_k127_5254464_0	cellulose binding	-	-	-	0.0	1167.0
REGS1_k127_5254464_1	Serine carboxypeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338	483.0
REGS1_k127_5254464_2	Protein of unknown function, DUF255	-	-	-	0.000000000000000000000000000000000000000000000000000000000000002313	229.0
REGS1_k127_5254464_3	Trehalose utilisation	-	-	-	0.00000000000000000000000000000001574	143.0
REGS1_k127_5254464_4	Domain of unknown function (DUF4342)	-	-	-	0.0002039	47.0
REGS1_k127_5330935_0	NAD(P) transhydrogenase beta subunit	K00325	-	1.6.1.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492	560.0
REGS1_k127_5330935_1	Alanine dehydrogenase/PNT, N-terminal domain	K00324	-	1.6.1.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671	477.0
REGS1_k127_5330935_10	X-Pro dipeptidyl-peptidase (S15 family)	K06889	-	-	0.000000000000000000000000003172	121.0
REGS1_k127_5330935_11	4TM region of pyridine nucleotide transhydrogenase, mitoch	K00324	-	1.6.1.2	0.000000000000000000000000004258	113.0
REGS1_k127_5330935_12	Protein of unknown function (DUF2662)	-	-	-	0.0000000000002225	74.0
REGS1_k127_5330935_13	lactate/malate dehydrogenase, NAD binding domain	K00024	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	0.0000000000008722	78.0
REGS1_k127_5330935_2	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K02005	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689	377.0
REGS1_k127_5330935_3	MacB-like periplasmic core domain	K02004	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779	342.0
REGS1_k127_5330935_4	MacB-like periplasmic core domain	K02004	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504	338.0
REGS1_k127_5330935_5	Tetratricopeptide repeats	K12132	-	2.7.11.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003835	312.0
REGS1_k127_5330935_6	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	K01754	-	4.3.1.19	0.000000000000000000000000000000000000000000000000000000000000000312	231.0
REGS1_k127_5330935_7	KR domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000007777	239.0
REGS1_k127_5330935_8	beta-lactamase domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000001606	216.0
REGS1_k127_5330935_9	RNA polymerase sigma factor	K03088	-	-	0.00000000000000000000000000007276	125.0
REGS1_k127_5397471_0	Zinc carboxypeptidase	-	-	-	0.0	1347.0
REGS1_k127_5397471_1	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	3.834e-296	942.0
REGS1_k127_5397471_10	helix_turn_helix, mercury resistance	-	-	-	0.000000000000000002631	94.0
REGS1_k127_5397471_11	-	-	-	-	0.00000000003059	71.0
REGS1_k127_5397471_12	Collagen alpha-1(VII) chain	K16628	GO:0001704,GO:0001706,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005581,GO:0005590,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005793,GO:0005798,GO:0006810,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006996,GO:0007275,GO:0007369,GO:0007492,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009888,GO:0009987,GO:0012505,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0022607,GO:0030020,GO:0030134,GO:0030135,GO:0030154,GO:0030198,GO:0030934,GO:0031012,GO:0031090,GO:0031410,GO:0031974,GO:0031982,GO:0032501,GO:0032502,GO:0032991,GO:0033116,GO:0035987,GO:0042802,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048598,GO:0048646,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0061024,GO:0062023,GO:0065003,GO:0070013,GO:0071840,GO:0090114,GO:0097708,GO:0098588,GO:0098644,GO:0098648,GO:0098652,GO:0099080	-	0.00009335	54.0
REGS1_k127_5397471_2	Carbohydrate family 9 binding domain-like	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169	453.0
REGS1_k127_5397471_3	COGs COG1629 Outer membrane receptor protein mostly Fe transport	K02014	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000005218	290.0
REGS1_k127_5397471_4	Alanine racemase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000005934	271.0
REGS1_k127_5397471_5	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K03585	-	-	0.000000000000000000000000000000000000001568	166.0
REGS1_k127_5397471_6	BMC	-	-	-	0.0000000000000000000000000000004779	124.0
REGS1_k127_5397471_7	WHG domain	-	-	-	0.00000000000000000000005053	109.0
REGS1_k127_5397471_8	Pterin 4 alpha carbinolamine dehydratase	K01724	-	4.2.1.96	0.000000000000000000009116	96.0
REGS1_k127_5397471_9	outer membrane efflux protein	-	-	-	0.0000000000000000008046	102.0
REGS1_k127_5402006_0	metallocarboxypeptidase activity	-	-	-	2.805e-202	648.0
REGS1_k127_5402006_1	PFAM tRNA synthetase, class II (D, K and N)	K01893	-	6.1.1.22	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244	618.0
REGS1_k127_5402006_10	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	0.0000000000000000000000000000000000000000000000000006773	207.0
REGS1_k127_5402006_11	Xylose isomerase-like TIM barrel	-	-	-	0.00000000000000000000000000000000000009988	153.0
REGS1_k127_5402006_12	Belongs to the RtcB family	K14415	-	6.5.1.3	0.00000000000000000000000000000000001638	142.0
REGS1_k127_5402006_13	Required for maturation of 30S ribosomal subunits	K09748	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	0.000000000000000000000000000000003248	136.0
REGS1_k127_5402006_14	Nucleotidyl transferase	K00966,K16881	-	2.7.7.13,5.4.2.8	0.0000000000000000000000000000001128	141.0
REGS1_k127_5402006_15	CYTH	K05873	-	4.6.1.1	0.00000000000000000000009245	110.0
REGS1_k127_5402006_16	Archease protein family (MTH1598/TM1083)	-	-	-	0.000000000000007134	79.0
REGS1_k127_5402006_17	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	K02519	-	-	0.00002442	53.0
REGS1_k127_5402006_2	Belongs to the RtcB family	K14415	-	6.5.1.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913	496.0
REGS1_k127_5402006_3	Participates in both transcription termination and antitermination	K02600	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834	451.0
REGS1_k127_5402006_4	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	K14441	-	2.8.4.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283	432.0
REGS1_k127_5402006_5	serine-type endopeptidase activity	K04771	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909	333.0
REGS1_k127_5402006_6	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001374	262.0
REGS1_k127_5402006_7	phosphotransferase related to Ser Thr protein kinases	K07102	-	2.7.1.221	0.0000000000000000000000000000000000000000000000000000000000000246	228.0
REGS1_k127_5402006_8	-	-	-	-	0.000000000000000000000000000000000000000000000000000000001613	211.0
REGS1_k127_5402006_9	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	0.00000000000000000000000000000000000000000000000000000009157	219.0
REGS1_k127_5535804_0	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	K03701	-	-	0.0	1092.0
REGS1_k127_5535804_1	cellulose binding	-	-	-	3.109e-263	840.0
REGS1_k127_5535804_2	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	K04771	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262	306.0
REGS1_k127_5535804_3	Belongs to the DNA glycosylase MPG family	K03652	-	3.2.2.21	0.00000000000000000000000000000000000000000003407	176.0
REGS1_k127_5535804_4	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	K02356	-	-	0.0000000000000000000000000000236	119.0
REGS1_k127_5535804_5	CS domain	K13993	-	-	0.00000000000000000000377	101.0
REGS1_k127_5535804_6	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	0.00000000000000000001357	100.0
REGS1_k127_5535804_7	-	-	-	-	0.000000000000000001223	96.0
REGS1_k127_5535804_8	O-acyltransferase activity	-	-	-	0.000000859	55.0
REGS1_k127_5535804_9	-	-	-	-	0.00001145	50.0
REGS1_k127_5560433_0	Dienelactone hydrolase family	-	-	-	1.007e-255	813.0
REGS1_k127_5560433_1	4-alpha-glucanotransferase	K00705	-	2.4.1.25	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149	565.0
REGS1_k127_5560433_2	Peptidase, M16	K07263	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095	521.0
REGS1_k127_5560433_3	Peptidase, M16	K07263	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277	415.0
REGS1_k127_5560433_4	PFAM Aminotransferase class I and II	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008	373.0
REGS1_k127_5560433_5	Subtilase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000001711	228.0
REGS1_k127_5560433_6	Acetyltransferase (GNAT) domain	K03790	-	2.3.1.128	0.00000000000000003298	91.0
REGS1_k127_5616607_0	Acyl-CoA dehydrogenase, C-terminal domain	K16173	-	1.3.99.32	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095	509.0
REGS1_k127_5616607_1	GDP-mannose 4,6 dehydratase	K01710	-	4.2.1.46	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084	477.0
REGS1_k127_5616607_10	Glycosyl transferases group 1	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166	304.0
REGS1_k127_5616607_11	S-adenosyl-l-methionine hydroxide adenosyltransferase	K22205	-	-	0.00000000000000000000000000000000000000000000000000000005945	214.0
REGS1_k127_5616607_12	MFS_1 like family	-	-	-	0.0000000000000000000000000000000000000000000000007156	190.0
REGS1_k127_5616607_13	Glycosyl transferase family group 2	K07011	-	-	0.000000000000000000000000000000000000000001291	177.0
REGS1_k127_5616607_14	Glycosyltransferase Family 4	-	-	-	0.00000000000000000000000000000000000000001881	168.0
REGS1_k127_5616607_15	Belongs to the thioredoxin family	K03671	-	-	0.000000000000000000000000000000000000002059	149.0
REGS1_k127_5616607_16	PFAM glycosyl transferase group 1	-	-	-	0.000000000000000000000000000000000000008662	156.0
REGS1_k127_5616607_17	Belongs to the SUA5 family	K07566	-	2.7.7.87	0.00000000000000000000000000000000000007865	149.0
REGS1_k127_5616607_18	Polymer-forming cytoskeletal	-	-	-	0.00000000000000000000000000002089	124.0
REGS1_k127_5616607_19	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	K08744	-	2.7.8.41	0.0000000000000000000000000001449	122.0
REGS1_k127_5616607_2	Synthesizes alpha-1,4-glucan chains using ADP-glucose	K00703	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129	464.0
REGS1_k127_5616607_20	peptidyl-tyrosine sulfation	-	-	-	0.00000000000000007644	91.0
REGS1_k127_5616607_21	methyltransferase activity	K18827	-	2.1.1.294,2.7.1.181	0.0000000555	63.0
REGS1_k127_5616607_22	Nuclear mitotic apparatus protein 1	K16808	GO:0000132,GO:0000226,GO:0000235,GO:0000278,GO:0000922,GO:0001578,GO:0003674,GO:0005198,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005818,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005881,GO:0005886,GO:0005938,GO:0006355,GO:0006357,GO:0006996,GO:0006997,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007088,GO:0007163,GO:0007346,GO:0008017,GO:0008022,GO:0008092,GO:0008150,GO:0008289,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010638,GO:0010646,GO:0010647,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016363,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0019904,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030010,GO:0030425,GO:0030510,GO:0030513,GO:0030856,GO:0030858,GO:0030863,GO:0030953,GO:0030981,GO:0031110,GO:0031112,GO:0031113,GO:0031116,GO:0031122,GO:0031323,GO:0031326,GO:0031334,GO:0031616,GO:0031974,GO:0031981,GO:0032271,GO:0032273,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0032886,GO:0032887,GO:0032888,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0035091,GO:0035371,GO:0036449,GO:0036477,GO:0040001,GO:0042634,GO:0042635,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0044085,GO:0044087,GO:0044089,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045595,GO:0045597,GO:0045604,GO:0045606,GO:0045616,GO:0045618,GO:0045682,GO:0045684,GO:0045787,GO:0045840,GO:0045931,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050793,GO:0050794,GO:0051010,GO:0051011,GO:0051049,GO:0051050,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051179,GO:0051225,GO:0051233,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051293,GO:0051294,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0051726,GO:0051783,GO:0051785,GO:0051797,GO:0051798,GO:0051983,GO:0051984,GO:0055028,GO:0055048,GO:0060236,GO:0060255,GO:0060341,GO:0061673,GO:0062033,GO:0065007,GO:0070013,GO:0070507,GO:0070840,GO:0070925,GO:0071840,GO:0071944,GO:0072686,GO:0080090,GO:0090068,GO:0090092,GO:0090100,GO:0090169,GO:0090224,GO:0090235,GO:0090287,GO:0097427,GO:0097431,GO:0097435,GO:0097447,GO:0097458,GO:0097574,GO:0097575,GO:0097718,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099568,GO:0099738,GO:0110028,GO:0120025,GO:0120038,GO:1902115,GO:1902117,GO:1902363,GO:1902365,GO:1902846,GO:1902850,GO:1902903,GO:1902905,GO:1903047,GO:1903506,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904776,GO:1904778,GO:1905720,GO:1905818,GO:1905820,GO:1905832,GO:1990023,GO:1990752,GO:2000026,GO:2000112,GO:2001141,GO:2001252	-	0.000000239	64.0
REGS1_k127_5616607_23	Belongs to the amidase family	-	-	-	0.00007796	47.0
REGS1_k127_5616607_24	cell wall organization	K18197	-	4.2.2.23	0.000426	53.0
REGS1_k127_5616607_3	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	K02446	-	3.1.3.11	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418	436.0
REGS1_k127_5616607_4	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	K00384,K03671,K22345	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9,4.3.1.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119	433.0
REGS1_k127_5616607_5	Bacterial sugar transferase	K03606	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461	436.0
REGS1_k127_5616607_6	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	K04487	-	2.8.1.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019	400.0
REGS1_k127_5616607_7	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	K03665	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389	380.0
REGS1_k127_5616607_8	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	K00566	-	2.8.1.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964	366.0
REGS1_k127_5616607_9	transferase activity, transferring glycosyl groups	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406	353.0
REGS1_k127_5663095_0	S-adenosylmethionine synthetase, C-terminal domain	K00789	-	2.5.1.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367	569.0
REGS1_k127_5663095_1	Permease YjgP YjgQ family protein	K07091,K11720	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766	387.0
REGS1_k127_5663095_2	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	K07106	-	4.2.1.126	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002666	288.0
REGS1_k127_5663095_3	recombinase XerD	K04763	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000004489	289.0
REGS1_k127_5663095_4	SMART phosphoesterase PHP domain protein	-	-	-	0.00000000000000000000000000000000000001234	167.0
REGS1_k127_5663095_5	PD-(D/E)XK nuclease superfamily	-	-	-	0.0000000000000000000000000000000000001372	148.0
REGS1_k127_5663095_6	GntR family transcriptional regulator	K07979	-	-	0.000000000000000000001097	99.0
REGS1_k127_5663095_7	Glucosamine-6-phosphate deaminase	K02564	-	3.5.99.6	0.00000000000000000002021	93.0
REGS1_k127_566941_0	Zinc carboxypeptidase	-	-	-	0.0	1033.0
REGS1_k127_566941_1	Gamma-glutamyltranspeptidase	K00681	-	2.3.2.2,3.4.19.13	3.018e-299	928.0
REGS1_k127_566941_2	Transporter associated domain	K03699	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923	474.0
REGS1_k127_566941_3	Transporter associated domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105	314.0
REGS1_k127_566941_4	Beta-lactamase	-	-	-	0.000008922	53.0
REGS1_k127_583721_0	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	K01870	-	6.1.1.5	0.0	1019.0
REGS1_k127_583721_1	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	K01338	-	3.4.21.53	8.713e-278	878.0
REGS1_k127_583721_10	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	K02493	-	2.1.1.297	0.000000000000000000000000000000000000000000000000000000007198	210.0
REGS1_k127_583721_11	Belongs to the FPP GGPP synthase family	K13789	-	2.5.1.1,2.5.1.10,2.5.1.29	0.0000000000000000000000000000000000000000000000000000005961	212.0
REGS1_k127_583721_12	carboxylic acid catabolic process	-	-	-	0.0000000000000000000000000000000000000000000000002197	186.0
REGS1_k127_583721_13	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	K00951	-	2.7.6.5	0.00000000000000000000000000000000000000000000006644	173.0
REGS1_k127_583721_14	Copper/zinc superoxide dismutase (SODC)	K04565	-	1.15.1.1	0.0000000000000000000000000000000000000000001611	166.0
REGS1_k127_583721_15	Methyltransferase domain	-	-	-	0.0000000000000000000000000000000000000000002515	167.0
REGS1_k127_583721_16	BioY family	K03523	-	-	0.000000000000000000000000000000000000000002011	164.0
REGS1_k127_583721_17	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family	K02503	-	-	0.00000000000000000000000000000000000000001273	163.0
REGS1_k127_583721_18	Endoribonuclease L-PSP	K09021,K09022	GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.99.10	0.00000000000000000000000000000000000000001324	156.0
REGS1_k127_583721_19	molybdopterin converting factor	K03635,K21142	-	2.8.1.12	0.0000000000000000000000000000000009289	137.0
REGS1_k127_583721_2	Fumarate hydratase (Fumerase)	K01676	-	4.2.1.2	1.07e-231	727.0
REGS1_k127_583721_20	Required for insertion of 4Fe-4S clusters	K15724	-	-	0.000000000000000000000000000000001497	133.0
REGS1_k127_583721_21	PFAM NUDIX hydrolase	K01515	-	3.6.1.13	0.0000000000000000000000000000008641	132.0
REGS1_k127_583721_22	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	K03101	-	3.4.23.36	0.0000000000000000000000000007079	132.0
REGS1_k127_583721_23	Belongs to the Fur family	K03711	-	-	0.00000000000000000000000007234	121.0
REGS1_k127_583721_24	Belongs to the bacterial ribosomal protein bL28 family	K02902	-	-	0.00000000000000000001436	92.0
REGS1_k127_583721_25	PFAM molybdopterin biosynthesis MoaE protein	K03635,K21142	-	2.8.1.12	0.0000000000000007404	82.0
REGS1_k127_583721_26	Prokaryotic dksA/traR C4-type zinc finger	K06204	-	-	0.000000000000001863	85.0
REGS1_k127_583721_27	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.0000000000006322	82.0
REGS1_k127_583721_28	HAD-hyrolase-like	-	-	-	0.00000000001274	72.0
REGS1_k127_583721_29	-	-	-	-	0.00000002172	59.0
REGS1_k127_583721_3	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	K02835	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961	454.0
REGS1_k127_583721_30	-	-	-	-	0.00000002573	63.0
REGS1_k127_583721_31	Branched-chain amino acid ATP-binding cassette transporter	K01995	-	-	0.0000006627	60.0
REGS1_k127_583721_4	Insulinase (Peptidase family M16)	K07263	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557	370.0
REGS1_k127_583721_5	Histone deacetylase domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844	303.0
REGS1_k127_583721_6	Responsible for synthesis of pseudouridine from uracil	K06180	-	5.4.99.23	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002606	293.0
REGS1_k127_583721_7	PFAM Phosphomethylpyrimidine kinase type-1	K00941	-	2.7.1.49,2.7.4.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002962	287.0
REGS1_k127_583721_8	Insulinase (Peptidase family M16)	K07263	-	-	0.000000000000000000000000000000000000000000000000000000000000000000001499	261.0
REGS1_k127_583721_9	SMART phosphoesterase PHP domain protein	K07053	-	3.1.3.97	0.000000000000000000000000000000000000000000000000000000001343	224.0
REGS1_k127_5847593_0	NADH dehydrogenase	-	-	-	6.741e-235	741.0
REGS1_k127_5847593_1	(ABC) transporter	K06147,K18890	-	-	1.791e-205	656.0
REGS1_k127_5847593_10	Histidine kinase HAMP	K02482	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144	439.0
REGS1_k127_5847593_11	ROK family	K00847	-	2.7.1.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682	405.0
REGS1_k127_5847593_12	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	K03388	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616	362.0
REGS1_k127_5847593_13	Heterodisulfide reductase, subunit B	K03389	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623	351.0
REGS1_k127_5847593_14	HMGL-like	K01640	-	4.1.3.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608	343.0
REGS1_k127_5847593_15	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	K00989,K02428	-	2.7.7.56,3.6.1.66	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751	317.0
REGS1_k127_5847593_16	Putative Fe-S cluster	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004261	309.0
REGS1_k127_5847593_17	Carboxypeptidase regulatory-like domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007537	305.0
REGS1_k127_5847593_18	Transglycosylase SLT domain	K08309	-	-	0.0000000000000000000000000000000000000000000000000000000000000000006235	256.0
REGS1_k127_5847593_19	Methyl-viologen-reducing hydrogenase, delta subunit	K14127,K14128	-	1.8.98.5,1.8.98.6	0.000000000000000000000000000000000000000000000000000000000000001037	223.0
REGS1_k127_5847593_2	3-isopropylmalate dehydratase activity	K01703	-	4.2.1.33,4.2.1.35	1.496e-201	638.0
REGS1_k127_5847593_20	3-isopropylmalate dehydratase activity	K01704	-	4.2.1.33,4.2.1.35	0.000000000000000000000000000000000000000000000000000000000000007235	220.0
REGS1_k127_5847593_21	4Fe-4S dicluster domain	K03389,K03390,K16887,K18930	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.00000000000000000000000000000000000000000000000000000001919	202.0
REGS1_k127_5847593_22	PHP-associated	K07053	-	3.1.3.97	0.0000000000000000000000000000000000000000000000000000008958	210.0
REGS1_k127_5847593_23	phosphorelay signal transduction system	-	-	-	0.000000000000000000000000000000000000000000000000004075	198.0
REGS1_k127_5847593_24	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	0.0000000000000000000000000000000000000000000000878	189.0
REGS1_k127_5847593_25	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	K02428	-	3.6.1.66	0.000000000000000000000000000000000000000000301	165.0
REGS1_k127_5847593_26	PFAM NADH ubiquinone oxidoreductase, 20 kDa subunit	K14128	-	1.8.98.5	0.0000000000000000000000000000000000000000005479	176.0
REGS1_k127_5847593_27	TIGRFAM hydrogenase maturation protease	K03605	-	-	0.0000000000000000000000000000000000000000005774	163.0
REGS1_k127_5847593_28	Ferredoxin	K17992	-	1.12.1.3	0.000000000000000000000000000000000000000019	156.0
REGS1_k127_5847593_29	PFAM ATP-binding region, ATPase domain protein	-	-	-	0.00000000000000000000000000000000000000002266	156.0
REGS1_k127_5847593_3	Nickel-dependent hydrogenase	K14126	-	1.8.98.5	7.653e-198	644.0
REGS1_k127_5847593_30	Ami_3	K01448	-	3.5.1.28	0.000000000000000000000000000000000000001267	166.0
REGS1_k127_5847593_31	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000000000000000000000000000004703	160.0
REGS1_k127_5847593_32	Thioredoxin-like [2Fe-2S] ferredoxin	K00334	-	1.6.5.3	0.0000000000000000000000000000000000001081	155.0
REGS1_k127_5847593_33	peptidyl-tyrosine sulfation	-	-	-	0.000000000000000000000000000000000005863	160.0
REGS1_k127_5847593_34	DRTGG domain	-	-	-	0.000000000000000000000000005763	117.0
REGS1_k127_5847593_35	DinB family	-	-	-	0.00000000000000000000001122	111.0
REGS1_k127_5847593_36	Sporulation and spore germination	-	-	-	0.0000000000000000000002293	108.0
REGS1_k127_5847593_37	DRTGG domain	-	-	-	0.000000000000000002526	91.0
REGS1_k127_5847593_38	GIY-YIG catalytic domain	K07461	-	-	0.00000000000000005381	93.0
REGS1_k127_5847593_39	3D domain	-	-	-	0.00000000000000007163	88.0
REGS1_k127_5847593_4	ABC transporter, transmembrane	K18889	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418	591.0
REGS1_k127_5847593_40	Uncharacterized protein conserved in bacteria (DUF2062)	K09928	-	-	0.0000000000000001112	89.0
REGS1_k127_5847593_41	nuclear chromosome segregation	-	-	-	0.000000000004569	79.0
REGS1_k127_5847593_42	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	0.000000004255	68.0
REGS1_k127_5847593_43	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	K00946	-	2.7.4.16	0.0000000347	58.0
REGS1_k127_5847593_44	-	-	-	-	0.0000009809	60.0
REGS1_k127_5847593_5	CoA-transferase family III	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441	574.0
REGS1_k127_5847593_6	Isocitrate/isopropylmalate dehydrogenase	K00052	-	1.1.1.85	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224	552.0
REGS1_k127_5847593_7	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	K03388	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787	531.0
REGS1_k127_5847593_8	WD40-like Beta Propeller Repeat	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039	461.0
REGS1_k127_5847593_9	response regulator	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283	443.0
REGS1_k127_5927502_0	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	K03070	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	2.223e-261	828.0
REGS1_k127_5927502_1	Belongs to the DEAD box helicase family	K11927	-	3.6.4.13	0.00000000000000000000000002072	111.0
REGS1_k127_5927502_3	Amidase	K21801	-	-	0.000001546	54.0
REGS1_k127_5949152_0	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	K00382	-	1.8.1.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155	457.0
REGS1_k127_5949152_1	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	K00658	-	2.3.1.61	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518	411.0
REGS1_k127_5949152_2	response regulator receiver	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454	404.0
REGS1_k127_5949152_3	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	K03801	-	2.3.1.181	0.000000000000000000000000000000000000000000000000000000000000000000153	237.0
REGS1_k127_5949152_4	PFAM Radical SAM domain protein	K06871	-	-	0.000000000000000000000000000000000000000000000000003421	201.0
REGS1_k127_5990414_0	X-Pro dipeptidyl-peptidase domain protein	K06978	-	-	0.0	1008.0
REGS1_k127_5990414_1	cellulose binding	-	-	-	2.142e-258	840.0
REGS1_k127_5990414_10	PFAM Radical SAM domain protein	-	-	-	0.00000000000000000000002705	116.0
REGS1_k127_5990414_11	polysaccharide deacetylase	-	-	-	0.0000000000000000000001849	111.0
REGS1_k127_5990414_12	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	0.00000000000000111	90.0
REGS1_k127_5990414_13	Uncharacterized protein family UPF0016	-	-	-	0.0000000000006277	76.0
REGS1_k127_5990414_14	Putative regulatory protein	-	-	-	0.00000000003577	64.0
REGS1_k127_5990414_2	Peptidase dimerisation domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826	529.0
REGS1_k127_5990414_3	Serine carboxypeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507	501.0
REGS1_k127_5990414_4	TIGRFAM glycosyltransferase, MGT family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576	351.0
REGS1_k127_5990414_5	radical SAM domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000008996	272.0
REGS1_k127_5990414_6	amidohydrolase	K07045	-	-	0.00000000000000000000000000000000000000000000000003294	197.0
REGS1_k127_5990414_8	Sulfotransferase domain	-	-	-	0.0000000000000000000000000000000000000163	158.0
REGS1_k127_5990414_9	Thioredoxin	K03672	-	1.8.1.8	0.000000000000000000000000000000002974	136.0
REGS1_k127_6071356_0	Sortilin, neurotensin receptor 3,	-	-	-	0.0	1041.0
REGS1_k127_6071356_1	WD40-like Beta Propeller Repeat	K03641,K07277	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853	559.0
REGS1_k127_6071356_10	Belongs to the sigma-70 factor family. ECF subfamily	K03088	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	0.0000000000000000000000000000000000000001428	157.0
REGS1_k127_6071356_11	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	K02199	-	-	0.0000000000000000000000000000000002778	138.0
REGS1_k127_6071356_12	-	-	-	-	0.00000000000000003668	84.0
REGS1_k127_6071356_13	Peptidase family M28	-	-	-	0.0000000000000000474	94.0
REGS1_k127_6071356_14	-	-	-	-	0.0000000000003975	76.0
REGS1_k127_6071356_15	Putative zinc-finger	-	-	-	0.0000003405	61.0
REGS1_k127_6071356_16	Trypsin-like peptidase domain	-	-	-	0.00001726	51.0
REGS1_k127_6071356_2	aromatic amino acid beta-eliminating lyase threonine aldolase	K01620	-	4.1.2.48	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765	417.0
REGS1_k127_6071356_3	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409	374.0
REGS1_k127_6071356_4	membrane	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379	343.0
REGS1_k127_6071356_5	Protein of unknown function (DUF1684)	K09164	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234	282.0
REGS1_k127_6071356_6	Endonuclease/Exonuclease/phosphatase family	-	-	-	0.0000000000000000000000000000000000000000000000000000004989	203.0
REGS1_k127_6071356_7	SCO1/SenC	K07152	-	-	0.00000000000000000000000000000000000000000001509	181.0
REGS1_k127_6071356_8	-	-	-	-	0.0000000000000000000000000000000000000000001774	172.0
REGS1_k127_6071356_9	domain protein	-	-	-	0.00000000000000000000000000000000000000001885	173.0
REGS1_k127_6136907_0	NADH-Ubiquinone oxidoreductase (complex I), chain 5	K00341	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774	624.0
REGS1_k127_6136907_1	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	K00342	-	1.6.5.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388	597.0
REGS1_k127_6136907_10	methyltransferase	-	-	-	0.00000000000000000000000000000000000000000000000007935	195.0
REGS1_k127_6136907_11	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	K03271	-	5.3.1.28	0.0000000000000000000000000000000000000000000000002222	184.0
REGS1_k127_6136907_12	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	K01711	-	4.2.1.47	0.000000000000000000000000000000000000003906	147.0
REGS1_k127_6136907_13	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00332	-	1.6.5.3	0.0000000000000000000000000000000000007118	146.0
REGS1_k127_6136907_14	Thioredoxin-like [2Fe-2S] ferredoxin	K00334	-	1.6.5.3	0.00000000000000000000000000000000001724	151.0
REGS1_k127_6136907_15	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	K00330	-	1.6.5.3	0.000000000000000000000000000000004507	134.0
REGS1_k127_6136907_16	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00340	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	0.0000000000000000000000000000007551	123.0
REGS1_k127_6136907_17	Belongs to the complex I subunit 6 family	K00339	-	1.6.5.3	0.00000000000000000000000003391	124.0
REGS1_k127_6136907_18	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	K03149	-	2.8.1.10	0.00000000000003519	74.0
REGS1_k127_6136907_2	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	K00335	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981	524.0
REGS1_k127_6136907_3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00333,K13378	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884	458.0
REGS1_k127_6136907_4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00343	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079	397.0
REGS1_k127_6136907_5	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	K03149	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846	385.0
REGS1_k127_6136907_6	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	K00337	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402	375.0
REGS1_k127_6136907_7	PFAM glycosyl transferase family 2	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614	362.0
REGS1_k127_6136907_8	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	K00331	-	1.6.5.3	0.0000000000000000000000000000000000000000000000000000000000000000000000002753	252.0
REGS1_k127_6136907_9	DTDP-4-dehydrorhamnose reductase	K00067	-	1.1.1.133	0.00000000000000000000000000000000000000000000000000000001365	211.0
REGS1_k127_6209304_0	efflux transmembrane transporter activity	-	-	-	2.495e-220	709.0
REGS1_k127_6209304_1	Oligopeptidase F	K08602	-	-	2.109e-205	656.0
REGS1_k127_6209304_10	Domain of Unknown Function (DUF349)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000005318	303.0
REGS1_k127_6209304_11	Amidohydrolase	K07045	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000001222	273.0
REGS1_k127_6209304_12	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K03767,K03768	-	5.2.1.8	0.00000000000000000000000000000000000000000000000000000000009911	212.0
REGS1_k127_6209304_13	Uncharacterised protein family UPF0047	-	-	-	0.00000000000000000000000000000000000000000009652	163.0
REGS1_k127_6209304_14	Transcriptional regulatory protein, C terminal	-	-	-	0.0000000000000000000000000000000000000002857	170.0
REGS1_k127_6209304_16	-	-	-	-	0.0000000000000000000000000001571	125.0
REGS1_k127_6209304_17	-	-	-	-	0.000000000000000000000007104	113.0
REGS1_k127_6209304_18	23S rRNA-intervening sequence protein	-	-	-	0.00000000000000000000009878	102.0
REGS1_k127_6209304_19	Rieske [2Fe-2S] domain	-	-	-	0.000000000008388	69.0
REGS1_k127_6209304_2	Amidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982	615.0
REGS1_k127_6209304_20	acyl carrier protein	-	-	-	0.00000006625	66.0
REGS1_k127_6209304_21	Major Facilitator	-	-	-	0.0000191	54.0
REGS1_k127_6209304_22	Catalyzes the sodium-dependent transport of glutamate	-	-	-	0.0000439	46.0
REGS1_k127_6209304_3	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	K01895	-	6.2.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343	573.0
REGS1_k127_6209304_4	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	K00639	-	2.3.1.29	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541	549.0
REGS1_k127_6209304_5	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	K00639	-	2.3.1.29	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902	511.0
REGS1_k127_6209304_6	aminopeptidase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354	496.0
REGS1_k127_6209304_7	Pfam Uncharacterised protein family UPF0047	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584	384.0
REGS1_k127_6209304_8	radical SAM domain protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132	306.0
REGS1_k127_6209304_9	PFAM virulence factor family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652	308.0
REGS1_k127_6272423_0	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512	508.0
REGS1_k127_6272423_1	peptidase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802	348.0
REGS1_k127_6272423_2	SWI complex, BAF60b domains	-	-	-	0.0000000000000000000000000000000296	128.0
REGS1_k127_6272423_3	COG0346 Lactoylglutathione lyase and related lyases	K01759	-	4.4.1.5	0.00000000000000000000000000000004752	130.0
REGS1_k127_6272423_6	TIGRFAM outer membrane autotransporter barrel domain protein	-	-	-	0.0000000107	62.0
REGS1_k127_6272423_7	transport, permease protein	K01992	-	-	0.0000008881	55.0
REGS1_k127_6272423_8	TIGRFAM redox-active disulfide protein 1	-	-	-	0.00001112	54.0
REGS1_k127_6272423_9	3-demethylubiquinone-9 3-O-methyltransferase activity	K00568,K20444	-	2.1.1.222,2.1.1.64	0.00007719	51.0
REGS1_k127_63112_0	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	K00266	-	1.4.1.13,1.4.1.14	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042	611.0
REGS1_k127_63112_1	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	K00169	-	1.2.7.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406	419.0
REGS1_k127_63112_10	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747	-	0.000000000000000000000000000000000000000000000000000000008675	207.0
REGS1_k127_63112_11	outer membrane efflux protein	-	-	-	0.0000000000000001327	85.0
REGS1_k127_63112_2	PFAM Thiamine pyrophosphate	K00170,K00187	-	1.2.7.1,1.2.7.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972	366.0
REGS1_k127_63112_3	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841	385.0
REGS1_k127_63112_4	PFAM ABC transporter	K01990,K09695	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968	345.0
REGS1_k127_63112_5	PFAM oxidoreductase FAD NAD(P)-binding domain protein	K00528	-	1.18.1.2,1.19.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223	334.0
REGS1_k127_63112_6	Transport permease protein	K01992	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904	329.0
REGS1_k127_63112_7	transport, permease protein	K01992	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003772	301.0
REGS1_k127_63112_8	PFAM thioesterase superfamily	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000003733	231.0
REGS1_k127_63112_9	Pyruvate ferredoxin/flavodoxin oxidoreductase	K00172,K00189	-	1.2.7.1,1.2.7.7	0.00000000000000000000000000000000000000000000000000000000001754	213.0
REGS1_k127_6340178_0	4Fe-4S dicluster domain	K00184	-	-	0.0	1166.0
REGS1_k127_6340178_1	ATPase, P-type (transporting), HAD superfamily, subfamily IC	K17686	-	3.6.3.54	2.086e-307	983.0
REGS1_k127_6340178_10	Protein of unknown function (DUF3341)	-	-	-	0.0000000000000000000000000000000000000000000000000000000002786	227.0
REGS1_k127_6340178_11	-	-	-	-	0.00000000000000000005836	94.0
REGS1_k127_6340178_2	Polysulphide reductase, NrfD	K00185	-	-	3.7e-207	653.0
REGS1_k127_6340178_3	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	K01679,K01744	-	4.2.1.2,4.3.1.1	1.94e-201	638.0
REGS1_k127_6340178_4	M61 glycyl aminopeptidase	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961	590.0
REGS1_k127_6340178_5	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644	413.0
REGS1_k127_6340178_6	Belongs to the arginase family	K01480	-	3.5.3.11	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391	346.0
REGS1_k127_6340178_7	Cytochrome c7 and related cytochrome c	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489	304.0
REGS1_k127_6340178_8	Integrase core domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000006281	274.0
REGS1_k127_6340178_9	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000004517	231.0
REGS1_k127_6367685_0	acetyl-CoA carboxylase, biotin carboxylase	K01961	-	6.3.4.14,6.4.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544	602.0
REGS1_k127_6367685_1	Belongs to the SIS family. GutQ KpsF subfamily	K01627,K03281,K06041	-	2.5.1.55,5.3.1.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495	349.0
REGS1_k127_6367685_2	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	K01491	-	1.5.1.5,3.5.4.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328	325.0
REGS1_k127_6367685_3	Belongs to the KdsA family	K01627	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475	317.0
REGS1_k127_6367685_4	Ion channel	K10716	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284	302.0
REGS1_k127_6367685_5	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	K19804	-	-	0.000000000000000000000000000000000000000000000000001069	199.0
REGS1_k127_6367685_6	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	K00859	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	0.00000000000000000000000000000000000000000169	162.0
REGS1_k127_6367685_7	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	K03270	-	3.1.3.45	0.0000000000000000000000000000000000000001164	158.0
REGS1_k127_6367685_8	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	K01937	-	6.3.4.2	0.000000000000000000000000000000000001712	140.0
REGS1_k127_6367685_9	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	K00788	-	2.5.1.3	0.0000000000000000000000000000000083	136.0
REGS1_k127_6419129_0	Type II secretion system (T2SS), protein E, N-terminal domain	K02454	-	-	4.495e-224	708.0
REGS1_k127_6419129_1	Type II/IV secretion system protein	K02669	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341	527.0
REGS1_k127_6419129_2	two component, sigma54 specific, transcriptional regulator, Fis family	K02667	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042	481.0
REGS1_k127_6419129_3	Type II secretion system (T2SS), protein F	K02455	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395	422.0
REGS1_k127_6419129_4	MacB-like periplasmic core domain	K02004	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914	312.0
REGS1_k127_6419129_5	His Kinase A (phosphoacceptor) domain	K02668	-	2.7.13.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127	317.0
REGS1_k127_6419129_6	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K02005,K15727	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000004801	273.0
REGS1_k127_6419129_7	Pfam:N_methyl_2	-	-	-	0.00000000000000001528	90.0
REGS1_k127_6419129_8	Yip1 domain	-	-	-	0.000000000004327	76.0
REGS1_k127_6419129_9	-	-	-	-	0.000001295	60.0
REGS1_k127_6502824_0	Methionine synthase	K00548	-	2.1.1.13	0.0	1444.0
REGS1_k127_6502824_1	esterase	-	-	-	6.339e-230	734.0
REGS1_k127_6502824_2	Methyladenine glycosylase	K01246	-	3.2.2.20	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001729	289.0
REGS1_k127_6502824_3	epimerase	K00329,K00356	-	1.6.5.3,1.6.99.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000003831	287.0
REGS1_k127_6502824_4	Major Facilitator Superfamily	-	-	-	0.00000000000000000000000000000000000000000003916	168.0
REGS1_k127_6502824_5	Protein of unknown function (DUF3014)	-	-	-	0.00000000000000000000000000000000000000264	157.0
REGS1_k127_6625711_0	Enterochelin esterase	-	-	-	7.66e-222	703.0
REGS1_k127_6625711_1	response regulator	-	-	-	4.872e-209	663.0
REGS1_k127_6625711_10	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313	315.0
REGS1_k127_6625711_11	Von Willebrand factor type A	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805	303.0
REGS1_k127_6625711_12	Glycine cleavage H-protein	-	-	-	0.000000000000000000000000000000000000000000000000000000001378	209.0
REGS1_k127_6625711_13	Glycine cleavage H-protein	-	-	-	0.000000000000000000000000000000000000000000000000008775	192.0
REGS1_k127_6625711_14	N-acyl-D-aspartate D-glutamate deacylase	K06015	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.81	0.000000000000000000000000000000000000000004598	159.0
REGS1_k127_6625711_15	Peptidase family M54	K06974	-	-	0.00000000000000000000000000000000000000004	174.0
REGS1_k127_6625711_16	cyclic nucleotide binding	K10914	-	-	0.00000000000000000000000000000000004781	143.0
REGS1_k127_6625711_17	von Willebrand factor, type A	-	-	-	0.000000000000000000000000000000000718	151.0
REGS1_k127_6625711_18	Protein of unknown function (DUF1624)	-	-	-	0.0000000000000000000000001189	124.0
REGS1_k127_6625711_2	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	K01251	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	8.133e-208	668.0
REGS1_k127_6625711_21	-	-	-	-	0.00001439	58.0
REGS1_k127_6625711_3	Carbohydrate family 9 binding domain-like	-	-	-	5.604e-200	650.0
REGS1_k127_6625711_4	HAMP domain	K02482	-	2.7.13.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599	513.0
REGS1_k127_6625711_5	PFAM Polysulphide reductase, NrfD	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066	477.0
REGS1_k127_6625711_6	von Willebrand factor, type A	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749	463.0
REGS1_k127_6625711_7	Associated with various cellular activities	K03924	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678	398.0
REGS1_k127_6625711_8	Belongs to the GHMP kinase family. GalK subfamily	K00849	-	2.7.1.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252	390.0
REGS1_k127_6625711_9	4Fe-4S dicluster domain	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047	330.0
REGS1_k127_6827699_0	Belongs to the ClpA ClpB family	K03696	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	1.987e-266	843.0
REGS1_k127_6827699_1	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	K09458	-	2.3.1.179	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213	576.0
REGS1_k127_6827699_10	Belongs to the enoyl-CoA hydratase isomerase family	K01715	-	4.2.1.17	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294	306.0
REGS1_k127_6827699_11	short-chain dehydrogenase reductase SDR	K00059	-	1.1.1.100	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034	282.0
REGS1_k127_6827699_12	Oxidoreductase family, NAD-binding Rossmann fold	K09949	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000001697	282.0
REGS1_k127_6827699_13	Protein of unknown function (DUF1009)	K09949	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000296	274.0
REGS1_k127_6827699_14	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	K00677	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.129	0.00000000000000000000000000000000000000000000000000000000000000000000000000002965	276.0
REGS1_k127_6827699_15	Cation efflux family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000145	257.0
REGS1_k127_6827699_16	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	K00791	-	2.5.1.75	0.00000000000000000000000000000000000000000000000000000000000000000000002779	252.0
REGS1_k127_6827699_17	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	K09810	-	-	0.000000000000000000000000000000000000000000000000000000000000000007778	243.0
REGS1_k127_6827699_18	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	K03183	-	2.1.1.163,2.1.1.201	0.0000000000000000000000000000000000000000000000000000000000003948	220.0
REGS1_k127_6827699_19	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	K00794	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	0.000000000000000000000000000000000000002884	155.0
REGS1_k127_6827699_2	tRNA synthetases class II (D, K and N)	K04567	-	6.1.1.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288	552.0
REGS1_k127_6827699_20	Carrier of the growing fatty acid chain in fatty acid biosynthesis	K02078	-	-	0.0000000000000000000000000002141	115.0
REGS1_k127_6827699_21	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	K03625	-	-	0.000000000000000000000000003139	123.0
REGS1_k127_6827699_22	Uncharacterized ACR, COG1399	K07040	-	-	0.0000000000000000000000008586	111.0
REGS1_k127_6827699_23	Ribosomal L32p protein family	K02911	-	-	0.000000000000000000002627	95.0
REGS1_k127_6827699_24	-	-	-	-	0.0000000000000000009492	91.0
REGS1_k127_6827699_25	VanZ like family	-	-	-	0.00000000000000009983	85.0
REGS1_k127_6827699_26	TonB C terminal	-	-	-	0.0000001107	64.0
REGS1_k127_6827699_27	Outer membrane protein (OmpH-like)	K06142	-	-	0.00000271	57.0
REGS1_k127_6827699_28	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	K03186	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.5.1.129	0.00006735	46.0
REGS1_k127_6827699_3	Phosphotransfer between the C1 and C5 carbon atoms of pentose	K01839	-	5.4.2.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159	446.0
REGS1_k127_6827699_4	TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase	K01129	-	3.1.5.1	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649	390.0
REGS1_k127_6827699_5	TIGRFAM outer membrane protein assembly complex, YaeT protein	K07277	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504	385.0
REGS1_k127_6827699_6	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	K09808	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015	340.0
REGS1_k127_6827699_7	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	K03621	-	2.3.1.15	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201	325.0
REGS1_k127_6827699_8	TIGRFAM malonyl CoA-acyl carrier protein transacylase	K00645	-	2.3.1.39	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136	329.0
REGS1_k127_6827699_9	Electron transfer flavoprotein domain	K03521	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598	302.0
REGS1_k127_6900579_0	Short chain dehydrogenase	-	-	-	1.17e-205	672.0
REGS1_k127_6900579_1	COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes	K08321,K11645	-	2.3.1.245,4.1.2.13	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135	439.0
REGS1_k127_6900579_10	ethanolamine catabolic process	K04027	-	-	0.000000000000000000000000000000000000007633	147.0
REGS1_k127_6900579_11	GDSL-like Lipase/Acylhydrolase	-	-	-	0.000000000000000000000000000000001617	146.0
REGS1_k127_6900579_12	PFAM YCII-related domain	K09780	-	-	0.000000000000000000000000006107	113.0
REGS1_k127_6900579_13	ethanolamine utilization protein EutN carboxysome structural protein Ccml	K04028,K08697	-	-	0.000000000000000000000000007462	120.0
REGS1_k127_6900579_14	Tetratricopeptide repeat	-	-	-	0.00000000000000000000000003558	116.0
REGS1_k127_6900579_15	Ethanolamine utilization protein EutN	-	-	-	0.000000000000000000831	90.0
REGS1_k127_6900579_16	Ethanolamine utilization protein EutN carboxysome structural protein Ccml	K04028	-	-	0.000000000000001707	79.0
REGS1_k127_6900579_17	PFAM YbbR family protein	-	-	-	0.00000000002011	75.0
REGS1_k127_6900579_18	COG2217 Cation transport ATPase	K01533,K17686	-	3.6.3.4,3.6.3.54	0.0006363	46.0
REGS1_k127_6900579_2	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696	463.0
REGS1_k127_6900579_3	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	K03431	-	5.4.2.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493	392.0
REGS1_k127_6900579_4	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	K00015	-	1.1.1.26	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634	302.0
REGS1_k127_6900579_5	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	K03474	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000002486	277.0
REGS1_k127_6900579_6	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000002613	255.0
REGS1_k127_6900579_7	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	K00796,K13941	-	2.5.1.15,2.7.6.3	0.0000000000000000000000000000000000000000000000000000000000000000000001477	249.0
REGS1_k127_6900579_8	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	K01142,K10773	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.11.2,4.2.99.18	0.0000000000000000000000000000000000000000000007182	171.0
REGS1_k127_6900579_9	Belongs to the ribulose-phosphate 3-epimerase family	K01783	-	5.1.3.1	0.0000000000000000000000000000000000000000000178	171.0
REGS1_k127_6914703_0	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	K01547	-	3.6.3.12	3.396e-309	959.0
REGS1_k127_6914703_1	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	K00372	-	-	5.646e-307	962.0
REGS1_k127_6914703_10	nitrite transmembrane transporter activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436	348.0
REGS1_k127_6914703_11	Zinc-binding dehydrogenase	K07538	-	1.1.1.368	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188	332.0
REGS1_k127_6914703_12	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051	323.0
REGS1_k127_6914703_13	4 iron, 4 sulfur cluster binding	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000002663	262.0
REGS1_k127_6914703_14	Histidine kinase	K07646	-	2.7.13.3	0.000000000000000000000000000000000000000000000000000000000000000006256	244.0
REGS1_k127_6914703_15	Two component transcriptional regulator, winged helix family	K07667	-	-	0.000000000000000000000000000000000000000000000000000000000000002701	238.0
REGS1_k127_6914703_16	PFAM ATPase, BadF BadG BcrA BcrD type	-	-	-	0.0000000000000000000000000000000000000000000000000000000000001344	234.0
REGS1_k127_6914703_17	KR domain	K00023,K00059	-	1.1.1.100,1.1.1.36	0.00000000000000000000000000000000000000000000000000000000003035	213.0
REGS1_k127_6914703_18	Enoyl-CoA hydratase/isomerase	K07537	-	4.2.1.100	0.0000000000000000000000000000000000000000000000000001306	207.0
REGS1_k127_6914703_19	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	K01548	-	3.6.3.12	0.00000000000000000000000000000000000000000000003859	176.0
REGS1_k127_6914703_2	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	8.703e-212	668.0
REGS1_k127_6914703_21	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	-	0.000000000000000000000000000000001926	144.0
REGS1_k127_6914703_22	hemerythrin HHE cation binding domain	-	-	-	0.000000000000000000002486	101.0
REGS1_k127_6914703_23	NosL	K19342	-	-	0.000000000001371	76.0
REGS1_k127_6914703_24	FeoA	K04758	-	-	0.000009598	49.0
REGS1_k127_6914703_3	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	K01546	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126	569.0
REGS1_k127_6914703_4	Enoyl-CoA hydratase/isomerase	K07539	-	3.7.1.21	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284	454.0
REGS1_k127_6914703_5	ATP-binding region, ATPase domain protein domain protein	K00384,K01338,K11527	-	1.8.1.9,2.7.13.3,3.4.21.53	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529	478.0
REGS1_k127_6914703_6	Osmosensitive K channel His kinase sensor	K07646	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222	447.0
REGS1_k127_6914703_7	Iron-sulfur cluster-binding domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135	428.0
REGS1_k127_6914703_8	2-hydroxyglutaryl-CoA dehydratase, D-component	K04113	-	1.3.7.8	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786	412.0
REGS1_k127_6914703_9	2-hydroxyglutaryl-CoA dehydratase, D-component	K04112	-	1.3.7.8	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752	354.0
REGS1_k127_6915335_0	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	K14652	-	3.5.4.25,4.1.99.12	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508	533.0
REGS1_k127_6915335_1	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	K03106	-	3.6.5.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192	481.0
REGS1_k127_6915335_10	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	K02860	GO:0008150,GO:0040007	-	0.000000000000000000000000002421	117.0
REGS1_k127_6915335_11	Tetratricopeptide repeat	-	-	-	0.000000000000000000000000002643	129.0
REGS1_k127_6915335_12	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	K00788	-	2.5.1.3	0.000000000000000000000000005396	119.0
REGS1_k127_6915335_13	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	K01975	-	3.1.4.58	0.00000000000000000000000001243	117.0
REGS1_k127_6915335_14	Belongs to the bacterial ribosomal protein bS16 family	K02959	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.000000000000000000000001212	106.0
REGS1_k127_6915335_15	KH domain	-	-	-	0.000000000000001082	83.0
REGS1_k127_6915335_16	Helix-turn-helix domain	-	-	-	0.00000000004156	71.0
REGS1_k127_6915335_17	Belongs to the CinA family	K03742,K03743	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.5.1.42	0.0000000001049	64.0
REGS1_k127_6915335_2	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	K03110	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494	313.0
REGS1_k127_6915335_3	Glycerol-3-phosphate dehydrogenase	K00057	-	1.1.1.94	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258	306.0
REGS1_k127_6915335_4	tRNA (Guanine-1)-methyltransferase	K00554	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003262	286.0
REGS1_k127_6915335_5	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	K11752	-	1.1.1.193,3.5.4.26	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009834	285.0
REGS1_k127_6915335_6	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	K03470	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	0.0000000000000000000000000000000000000000000000000007209	191.0
REGS1_k127_6915335_7	riboflavin synthase, alpha	K00793	-	2.5.1.9	0.00000000000000000000000000000000000001353	151.0
REGS1_k127_6915335_8	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	K02884	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.00000000000000000000000000000000009143	147.0
REGS1_k127_6915335_9	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	K08591	-	2.3.1.15	0.0000000000000000000000000000000004301	139.0
REGS1_k127_6974124_0	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	K11717	-	2.8.1.7,4.4.1.16	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497	571.0
REGS1_k127_6974124_1	iron-sulfur cluster assembly	K07033,K09014	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338	515.0
REGS1_k127_6974124_2	FeS assembly ATPase SufC	K09013	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532	366.0
REGS1_k127_6974124_3	iron-sulfur cluster assembly	K07033,K09015	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211	393.0
REGS1_k127_6974124_4	NifU-like N terminal domain	K04488	-	-	0.00000000000000000000000000000000000000000000000000000192	212.0
REGS1_k127_6974124_5	2OG-Fe(II) oxygenase superfamily	-	-	-	0.000000000000000000000000000000000000000000000000002884	188.0
REGS1_k127_6974124_6	PaaD-like protein	-	-	-	0.000000000000000000000000000000002998	134.0
REGS1_k127_6974124_7	Subtilase family	-	-	-	0.000000000000000000000000271	108.0
REGS1_k127_6974124_8	aminopeptidase N	-	-	-	0.00000004575	65.0
REGS1_k127_6976236_0	Peptidase S9, prolyl oligopeptidase active site domain protein	K01322	-	3.4.21.26	2.857e-218	709.0
REGS1_k127_6976236_1	Peptidase, M61	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304	570.0
REGS1_k127_6976236_10	-	-	-	-	0.000000000000000000000003593	114.0
REGS1_k127_6976236_11	Calcineurin-like phosphoesterase	-	-	-	0.00000000000000000000008903	109.0
REGS1_k127_6976236_12	Calcineurin-like phosphoesterase	-	-	-	0.000000000000000000001222	105.0
REGS1_k127_6976236_13	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	K02518	-	-	0.000000000000000000004359	94.0
REGS1_k127_6976236_14	Calcineurin-like phosphoesterase	-	-	-	0.00000000000000001072	96.0
REGS1_k127_6976236_15	oxidation-reduction process	K09022	-	3.5.99.10	0.000000000000002486	88.0
REGS1_k127_6976236_16	Endoribonuclease L-PSP	K09022	-	3.5.99.10	0.0000000000002448	82.0
REGS1_k127_6976236_17	cellulase activity	-	-	-	0.0000000007753	71.0
REGS1_k127_6976236_2	Protein of unknown function (DUF1722)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849	361.0
REGS1_k127_6976236_3	Sigma factor PP2C-like phosphatases	K07315	-	3.1.3.3	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024	323.0
REGS1_k127_6976236_4	Belongs to the bacterial glucokinase family	K00845	-	2.7.1.2	0.0000000000000000000000000000000000000000000000000000000000000000000000002668	258.0
REGS1_k127_6976236_5	Ribosomal RNA adenine dimethylase	K00573	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	0.000000000000000000000000000000000000000000000000000000000000000000001083	244.0
REGS1_k127_6976236_6	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K01802,K03767,K03768	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	0.0000000000000000000000000000000000000000000000000000000000000006715	226.0
REGS1_k127_6976236_7	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	0.000000000000000000000000000000000000000000000009546	188.0
REGS1_k127_6976236_8	Phosphate acyltransferases	K01897	-	6.2.1.3	0.000000000000000000000000000000000000001497	151.0
REGS1_k127_6976236_9	O-linked GlcNAc transferase	-	-	-	0.0000000000000000000000000001262	129.0
REGS1_k127_6977201_0	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	K01214	-	3.2.1.68	4.351e-306	953.0
REGS1_k127_6977201_1	alpha amylase catalytic	K01182,K05343	-	3.2.1.1,3.2.1.10,5.4.99.16	6.443e-285	885.0
REGS1_k127_6977201_11	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	K01159	-	3.1.22.4	0.000000000000000000000000000000000000001999	161.0
REGS1_k127_6977201_12	Belongs to the peptidase M48B family	-	-	-	0.0000000000000000000000000002014	130.0
REGS1_k127_6977201_13	Outer membrane protein beta-barrel family	K16087,K16092	-	-	0.0000000000000000000006879	111.0
REGS1_k127_6977201_14	Methyltransferase type 12	-	-	-	0.0000000000000000002017	102.0
REGS1_k127_6977201_15	Penicillinase repressor	-	-	-	0.0000000000000000005586	92.0
REGS1_k127_6977201_16	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	0.000000000004291	77.0
REGS1_k127_6977201_17	TonB dependent receptor	K02014,K16087	-	-	0.00000001691	63.0
REGS1_k127_6977201_2	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	K03798	-	-	3.202e-259	824.0
REGS1_k127_6977201_3	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	K03551	-	3.6.4.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268	460.0
REGS1_k127_6977201_4	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	K00648	-	2.3.1.180	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103	447.0
REGS1_k127_6977201_5	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	K07568	-	2.4.99.17	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569	345.0
REGS1_k127_6977201_6	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835	331.0
REGS1_k127_6977201_7	transcriptional regulatory protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237	329.0
REGS1_k127_6977201_8	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	K04075	-	6.3.4.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000001384	279.0
REGS1_k127_6977201_9	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	K03550	-	3.6.4.12	0.00000000000000000000000000000000000000000000000000000001735	203.0
REGS1_k127_7013625_0	Belongs to the GARS family	K01945	-	6.3.4.13	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663	404.0
REGS1_k127_7013625_1	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	K06941	GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363	2.1.1.192	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819	350.0
REGS1_k127_7013625_2	Uncharacterized protein family UPF0004	K18707	-	2.8.4.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005433	300.0
REGS1_k127_7013625_3	Belongs to the peptidase M16 family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000005679	221.0
REGS1_k127_7013625_4	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	K01945	-	6.3.4.13	0.000000000000000000000000000000000000000000000000101	182.0
REGS1_k127_7013625_5	Nitrous oxide-stimulated promoter	-	-	-	0.0000000000000000000000000000002587	127.0
REGS1_k127_7142957_0	MacB-like periplasmic core domain	-	-	-	4.026e-230	737.0
REGS1_k127_7142957_1	ABC transporter	K02003	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000002201	265.0
REGS1_k127_7142957_2	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000233	243.0
REGS1_k127_7142957_3	MacB-like periplasmic core domain	-	-	-	0.00000000000000000000000000000000000000000000000007409	194.0
REGS1_k127_7142957_4	Outer membrane lipoprotein-sorting protein	-	-	-	0.000000000000000000000000000000000000000000000002232	183.0
REGS1_k127_7142957_5	COGs COG1629 Outer membrane receptor protein mostly Fe transport	K02014	-	-	0.00000000000000000000000000000000000004905	162.0
REGS1_k127_7142957_6	MacB-like periplasmic core domain	-	-	-	0.0000000000000000000000000000002931	143.0
REGS1_k127_7142957_7	-	-	-	-	0.000000000000002117	88.0
REGS1_k127_7145525_0	Zinc carboxypeptidase	-	-	-	0.0	1149.0
REGS1_k127_7145525_1	Phosphate acyltransferases	K00655,K01897	-	2.3.1.51,6.2.1.3	1.186e-237	764.0
REGS1_k127_7145525_2	Phosphoesterase family	-	-	-	4.006e-223	719.0
REGS1_k127_7145525_3	Amidase	K01426	-	3.5.1.4	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086	528.0
REGS1_k127_7145525_4	tRNA pseudouridine synthase activity	K06173	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477	305.0
REGS1_k127_7145525_5	Amidinotransferase	K01482	-	3.5.3.18	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003929	282.0
REGS1_k127_7145525_7	oxidation-reduction process	K09022	-	3.5.99.10	0.000000000000000000000000000000000000000000000000006833	183.0
REGS1_k127_7145525_8	O-methyltransferase activity	K15256	-	-	0.000000000000000000000000000000000000967	149.0
REGS1_k127_7145525_9	Low molecular weight phosphotyrosine protein phosphatase	K01104,K20201	-	3.1.3.48,3.9.1.2	0.00000000000000000002244	97.0
REGS1_k127_7217634_0	peptidyl-tyrosine sulfation	K01277	-	3.4.14.4	9.395e-299	930.0
REGS1_k127_7217634_1	decarboxylase	K01593	-	4.1.1.105,4.1.1.28	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066	496.0
REGS1_k127_7217634_2	Beta-Casp domain	K07576	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659	481.0
REGS1_k127_7217634_3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K03768	-	5.2.1.8	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288	378.0
REGS1_k127_7217634_4	Aminotransferase	K00812	-	2.6.1.1	0.00000000000000000000000000000000000000000000000000000000000000000000000003581	264.0
REGS1_k127_7217634_5	Pyridoxal-phosphate dependent enzyme	K05396	-	4.4.1.15	0.00000000000000000000000000000000000000000000000000000000000000001532	235.0
REGS1_k127_7217634_6	Short-chain dehydrogenase reductase SDR	K03793	-	1.5.1.33	0.0000000000000000000000000000000000000000000005399	175.0
REGS1_k127_7217634_7	PFAM Cyclic nucleotide-binding	K10914,K21563	-	-	0.000000000000000000000003708	112.0
REGS1_k127_7217634_8	-	-	-	-	0.00000000000000000000002322	108.0
REGS1_k127_7241792_0	FtsX-like permease family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899	502.0
REGS1_k127_7241792_1	protease-associated PA domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893	484.0
REGS1_k127_7241792_2	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	K03307	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707	362.0
REGS1_k127_7241792_3	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	K02003,K09810	-	-	0.00000000000000000000000000000000000000000000000000000000001015	216.0
REGS1_k127_7241792_4	TamB, inner membrane protein subunit of TAM complex	K09800	-	-	0.000001071	63.0
REGS1_k127_7257978_0	PFAM BNR Asp-box repeat	-	-	-	0.0	1229.0
REGS1_k127_7257978_1	metallocarboxypeptidase activity	K14054	-	-	0.0	1127.0
REGS1_k127_7257978_10	OsmC-like protein	K07397	-	-	0.0000000000000000002023	93.0
REGS1_k127_7257978_11	Carboxypeptidase regulatory-like domain	-	-	-	0.0000000000000008186	84.0
REGS1_k127_7257978_13	DNA-sulfur modification-associated	-	-	-	0.000006955	58.0
REGS1_k127_7257978_2	5TM C-terminal transporter carbon starvation CstA	K06200	-	-	1.3e-322	1004.0
REGS1_k127_7257978_3	Peptidase family M28	-	-	-	5.286e-309	982.0
REGS1_k127_7257978_4	PFAM peptidase S45 penicillin amidase	K01434	-	3.5.1.11	4.66e-218	707.0
REGS1_k127_7257978_5	PFAM peptidase M19 renal dipeptidase	K01273	-	3.4.13.19	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338	455.0
REGS1_k127_7257978_6	Aminotransferase class-V	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000001549	274.0
REGS1_k127_7257978_7	high-affinity ferrous iron transmembrane transporter activity	K07243	-	-	0.00000000000000000000000000000000000000000000000001158	190.0
REGS1_k127_7257978_8	Tetratricopeptide repeat	-	-	-	0.00000000000000000000000000000000000009899	154.0
REGS1_k127_7257978_9	von Willebrand factor, type A	K07114	-	-	0.0000000000000000000001491	110.0
REGS1_k127_7489217_0	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	K01905,K22224	-	6.2.1.13	5.045e-235	761.0
REGS1_k127_7489217_1	response regulator	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384	469.0
REGS1_k127_7489217_2	Histidine kinase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109	337.0
REGS1_k127_7489217_3	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	0.000000000000000000000000000005055	126.0
REGS1_k127_7489217_4	Domains REC, sigma54 interaction, HTH8	-	-	-	0.000000000000000002207	100.0
REGS1_k127_7489217_5	Zinc-binding dehydrogenase	K00008,K00148,K18369	-	1.1.1.14,1.2.1.46	0.00000000338	64.0
REGS1_k127_7582277_0	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	K14162	-	2.7.7.7	0.0	1181.0
REGS1_k127_7582277_1	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718	481.0
REGS1_k127_7582277_10	Protein of unknown function DUF47	K07220	-	-	0.0000000000000000000000000000000000000000000000000005882	193.0
REGS1_k127_7582277_11	recA bacterial DNA recombination protein	-	-	-	0.0000000000000000000000006751	114.0
REGS1_k127_7582277_12	Protein of unknown function (DUF3891)	-	-	-	0.00000000001152	78.0
REGS1_k127_7582277_2	radical SAM domain protein	K15045	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129	462.0
REGS1_k127_7582277_3	Radical SAM	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858	439.0
REGS1_k127_7582277_4	PFAM phosphate transporter	K03306	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207	394.0
REGS1_k127_7582277_5	Transmembrane secretion effector	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004	363.0
REGS1_k127_7582277_6	Succinylglutamate desuccinylase / Aspartoacylase family	K06987	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146	360.0
REGS1_k127_7582277_7	histidine kinase HAMP region domain protein	K07636	-	2.7.13.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402	361.0
REGS1_k127_7582277_8	Transcriptional regulatory protein, C terminal	K07658	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000003809	258.0
REGS1_k127_7582277_9	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	0.000000000000000000000000000000000000000000000000000000000005562	230.0
REGS1_k127_7675361_0	ABC transporter	K15738	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	1.95e-289	900.0
REGS1_k127_7675361_1	aminopeptidase activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416	574.0
REGS1_k127_7675361_10	Protein kinase domain	K08884,K12132	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	0.00001807	58.0
REGS1_k127_7675361_11	energy transducer activity	K03646,K03832	-	-	0.0001144	55.0
REGS1_k127_7675361_2	Radical SAM superfamily	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117	353.0
REGS1_k127_7675361_3	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	K01845	-	5.4.3.8	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593	352.0
REGS1_k127_7675361_4	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	K02346	-	2.7.7.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632	339.0
REGS1_k127_7675361_5	Memo-like protein	K06990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546	306.0
REGS1_k127_7675361_6	Gamma-glutamyltranspeptidase	K00681	-	2.3.2.2,3.4.19.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000002644	289.0
REGS1_k127_7675361_7	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	K00797	-	2.5.1.16	0.000000000000000000000000000000000000000000000007744	195.0
REGS1_k127_7675361_8	PFAM PEGA domain	-	-	-	0.000000000000000000248	103.0
REGS1_k127_7675361_9	regulation of methylation-dependent chromatin silencing	K07454	-	-	0.000000002329	60.0
REGS1_k127_7701044_0	Sortilin, neurotensin receptor 3,	-	-	-	9.893e-302	957.0
REGS1_k127_7701044_1	Cytochrome c-type biogenesis protein	K02198	-	-	1.387e-253	806.0
REGS1_k127_7701044_10	Shikimate kinase	K00891	-	2.7.1.71	0.000000000000000000000000008215	123.0
REGS1_k127_7701044_11	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	K02197	-	-	0.0000000000000001502	85.0
REGS1_k127_7701044_13	-	-	-	-	0.0000007089	60.0
REGS1_k127_7701044_2	Belongs to the thiolase family	K00626	-	2.3.1.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851	486.0
REGS1_k127_7701044_3	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	K00074	-	1.1.1.157	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494	346.0
REGS1_k127_7701044_4	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	K00800	-	2.5.1.19	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026	318.0
REGS1_k127_7701044_5	Calcineurin-like phosphoesterase superfamily domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000003807	242.0
REGS1_k127_7701044_6	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	K02194	-	-	0.0000000000000000000000000000000000000000000000000000000000002316	219.0
REGS1_k127_7701044_7	Maf-like protein	K06287	-	-	0.00000000000000000000000000000000000000000000000000004737	193.0
REGS1_k127_7701044_8	Cytochrome C assembly protein	K02195	-	-	0.000000000000000000000000000000000000000000000000005105	188.0
REGS1_k127_7701044_9	ABC transporter	K02193	-	3.6.3.41	0.000000000000000000000000000000000000000000001712	186.0
REGS1_k127_7728718_0	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	K01868	-	6.1.1.3	4.889e-213	682.0
REGS1_k127_7728718_1	Endoribonuclease that initiates mRNA decay	K18682	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045	518.0
REGS1_k127_7728718_10	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	K00946	-	2.7.4.16	0.00000000000000000000000000000000000000000000001669	180.0
REGS1_k127_7728718_11	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	K02887	-	-	0.0000000000000000000000000000000000000189	147.0
REGS1_k127_7728718_12	peptidase	-	-	-	0.000000000000000000000000000001232	138.0
REGS1_k127_7728718_13	Belongs to the FPP GGPP synthase family	K13789	-	2.5.1.1,2.5.1.10,2.5.1.29	0.00000000000000000000000000284	116.0
REGS1_k127_7728718_14	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	K07447	-	-	0.000000000000000000000004235	108.0
REGS1_k127_7728718_15	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	K03530	-	-	0.00000000000000000000001056	102.0
REGS1_k127_7728718_16	structural constituent of ribosome	K02916	-	-	0.000000000000001014	83.0
REGS1_k127_7728718_17	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	K09888	-	-	0.000000003869	62.0
REGS1_k127_7728718_2	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231	442.0
REGS1_k127_7728718_3	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	K01890	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711	435.0
REGS1_k127_7728718_4	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	K01889	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609	402.0
REGS1_k127_7728718_5	FtsJ-like methyltransferase	K06442	GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.226,2.1.1.227	0.00000000000000000000000000000000000000000000000000000000000000000000006728	254.0
REGS1_k127_7728718_6	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	K07082	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000105	252.0
REGS1_k127_7728718_7	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	K00858	-	2.7.1.23	0.0000000000000000000000000000000000000000000000000000000000000000000001328	250.0
REGS1_k127_7728718_8	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	K02520	-	-	0.000000000000000000000000000000000000000000000000000000000859	206.0
REGS1_k127_7728718_9	tail specific protease	K03797	-	3.4.21.102	0.000000000000000000000000000000000000000000000000001122	198.0
REGS1_k127_7749670_0	Acyl-CoA dehydrogenase, N-terminal domain	K00248,K00249,K18244	-	1.3.8.1,1.3.8.7	4.373e-203	637.0
REGS1_k127_7749670_1	Belongs to the aldehyde dehydrogenase family	K00128,K00130	-	1.2.1.3,1.2.1.8	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401	516.0
REGS1_k127_7749670_10	N-terminal half of MaoC dehydratase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007294	275.0
REGS1_k127_7749670_11	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	K02481,K07713	GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000005997	273.0
REGS1_k127_7749670_12	Subtilase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000001078	263.0
REGS1_k127_7749670_13	Belongs to the metallo-dependent hydrolases superfamily. NagA family	K01443	-	3.5.1.25	0.00000000000000000000000000000000000000000000000000000000000001385	233.0
REGS1_k127_7749670_14	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	K06920	-	6.3.4.20	0.0000000000000000000000000000000000000000000000008602	183.0
REGS1_k127_7749670_15	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	0.0000000000000000000000000000000000000000000003221	179.0
REGS1_k127_7749670_16	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	K03183	-	2.1.1.163,2.1.1.201	0.00000000000000000000000000000000000000000004244	173.0
REGS1_k127_7749670_17	COG0720 6-pyruvoyl-tetrahydropterin synthase	K01737	-	4.1.2.50,4.2.3.12	0.00000000000000000000000000000000000000000005863	164.0
REGS1_k127_7749670_18	domain, Protein	-	-	-	0.0000000000000000000000002916	121.0
REGS1_k127_7749670_19	Oxidoreductase FAD-binding domain	-	-	-	0.0000000000000000000006985	104.0
REGS1_k127_7749670_2	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036	527.0
REGS1_k127_7749670_20	-	-	-	-	0.00000000000000000002492	102.0
REGS1_k127_7749670_21	ROK family	K00845	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	0.0000000000000004094	89.0
REGS1_k127_7749670_22	phosphoesterase, PA-phosphatase related	-	-	-	0.0000000000002306	78.0
REGS1_k127_7749670_23	BON domain	-	-	-	0.00000000003234	73.0
REGS1_k127_7749670_25	-	-	-	-	0.000001609	61.0
REGS1_k127_7749670_26	-	-	-	-	0.00002136	57.0
REGS1_k127_7749670_3	Belongs to the UPF0441 family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605	458.0
REGS1_k127_7749670_4	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694	456.0
REGS1_k127_7749670_5	HD domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955	472.0
REGS1_k127_7749670_6	Deoxyhypusine synthase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918	391.0
REGS1_k127_7749670_7	Belongs to the peptidase S41A family	K03797	-	3.4.21.102	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229	365.0
REGS1_k127_7749670_8	Thiamine pyrophosphate enzyme, central domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126	350.0
REGS1_k127_7749670_9	Enoyl- acyl-carrier-protein reductase NADH	K00208	-	1.3.1.10,1.3.1.9	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796	301.0
REGS1_k127_7903050_0	cellulose binding	-	-	-	0.0	1274.0
REGS1_k127_7903050_1	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	K08352	-	1.8.5.5	0.0	1109.0
REGS1_k127_7903050_10	efflux transmembrane transporter activity	K02004	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013	528.0
REGS1_k127_7903050_11	symporter activity	K03307	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036	471.0
REGS1_k127_7903050_12	PFAM peptidase S1 and S6, chymotrypsin Hap	K04771	-	3.4.21.107	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844	431.0
REGS1_k127_7903050_13	PFAM peptidase S58, DmpA	K01266	-	3.4.11.19	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557	369.0
REGS1_k127_7903050_14	histidine kinase HAMP region domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127	360.0
REGS1_k127_7903050_15	Polysulphide reductase, NrfD	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571	346.0
REGS1_k127_7903050_16	4 iron, 4 sulfur cluster binding	K04014,K08353,K08358,K16293	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428	308.0
REGS1_k127_7903050_17	response regulator, receiver	K02483	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678	316.0
REGS1_k127_7903050_18	Carboxypeptidase regulatory-like domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000007724	269.0
REGS1_k127_7903050_19	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	K00406,K01011,K07112	-	2.8.1.1,2.8.1.2	0.0000000000000000000000000000000000000000000000000000000000000000003879	233.0
REGS1_k127_7903050_2	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	K01585	-	4.1.1.19	4.294e-299	934.0
REGS1_k127_7903050_20	6-phosphogluconolactonase	K01057	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	0.000000000000000000000000000000000000000000000000000000000000000001934	235.0
REGS1_k127_7903050_21	Cupin 2, conserved barrel domain protein	K13640	-	-	0.00000000000000000000000000000000000000000000000000000000001677	216.0
REGS1_k127_7903050_22	-	K07112	-	-	0.00000000000000000000000000000000000000000000000000000000001921	214.0
REGS1_k127_7903050_24	Ribose/Galactose Isomerase	K01808	-	5.3.1.6	0.00000000000000000000000000000000000000000000000293	181.0
REGS1_k127_7903050_25	-	-	-	-	0.000000000000000000000000000000000000000000004272	168.0
REGS1_k127_7903050_26	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	0.000000000000000000000000000000000000000152	170.0
REGS1_k127_7903050_27	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.00000000000000000000000000000000000001199	152.0
REGS1_k127_7903050_28	peptidyl-tyrosine sulfation	K13992	-	-	0.000000009802	61.0
REGS1_k127_7903050_29	LTXXQ motif family protein	K06006	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507	-	0.00001869	55.0
REGS1_k127_7903050_3	Transaldolase/Fructose-6-phosphate aldolase	K00616	-	2.2.1.2	2.801e-220	699.0
REGS1_k127_7903050_30	-	-	-	-	0.00003546	55.0
REGS1_k127_7903050_4	Amino acid permease	-	-	-	5.13e-211	673.0
REGS1_k127_7903050_5	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	K00036	-	1.1.1.363,1.1.1.49	8.776e-208	658.0
REGS1_k127_7903050_6	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	4.333e-207	670.0
REGS1_k127_7903050_7	succinyl-diaminopimelate desuccinylase activity	K01439	-	3.5.1.18	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656	592.0
REGS1_k127_7903050_8	PFAM Aldehyde dehydrogenase family	K00128,K00140	-	1.2.1.18,1.2.1.27,1.2.1.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247	575.0
REGS1_k127_7903050_9	Aminotransferase class-III	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309	565.0
REGS1_k127_8023650_0	serine-type peptidase activity	-	-	-	8.675e-198	643.0
REGS1_k127_8023650_1	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	K01739,K01761	-	2.5.1.48,4.4.1.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334	440.0
REGS1_k127_8023650_2	-	-	-	-	0.000004761	53.0
REGS1_k127_8023650_3	ubiE/COQ5 methyltransferase family	-	-	-	0.00003169	54.0
REGS1_k127_8066110_0	Tricorn protease homolog	-	-	-	0.0	1037.0
REGS1_k127_8066110_1	membrane organization	K07277	-	-	0.00000005301	64.0
REGS1_k127_8079275_0	PUA-like domain	K00958	-	2.7.7.4	2.286e-241	770.0
REGS1_k127_8079275_1	TrkA-C domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209	572.0
REGS1_k127_8079275_2	ABC-2 family transporter protein	K01992	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219	385.0
REGS1_k127_8079275_3	pfam abc	K01990	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674	339.0
REGS1_k127_8079275_4	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.00000000000000000000000000000000000000000000008727	183.0
REGS1_k127_8079275_5	Biotin-lipoyl like	K01993	-	-	0.0000000000000000000000000000000000000000007924	175.0
REGS1_k127_8079275_6	DNA polymerase alpha chain like domain	K07053	-	3.1.3.97	0.00000000001677	66.0
REGS1_k127_8082006_0	cellulose binding	-	-	-	0.0	1257.0
REGS1_k127_8082006_1	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	K01681	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	0.0	1169.0
REGS1_k127_8082006_10	Peptidase family M28	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489	452.0
REGS1_k127_8082006_11	Zinc-binding dehydrogenase	K00344	-	1.6.5.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245	351.0
REGS1_k127_8082006_12	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	K02536	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121	341.0
REGS1_k127_8082006_13	Belongs to the peptidase M16 family	K07263	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375	350.0
REGS1_k127_8082006_14	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	K18979	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689	327.0
REGS1_k127_8082006_15	Insulinase (Peptidase family M16)	K07263	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062	324.0
REGS1_k127_8082006_16	Ornithine cyclodeaminase/mu-crystallin family	K01750	-	4.3.1.12	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382	297.0
REGS1_k127_8082006_17	Rhomboid family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000006739	291.0
REGS1_k127_8082006_18	HEAT repeats	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001007	286.0
REGS1_k127_8082006_19	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	K00748	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	0.00000000000000000000000000000000000000000000000000000000000000000000000000000003236	299.0
REGS1_k127_8082006_2	protein secretion by the type I secretion system	K11085	-	-	7.201e-250	785.0
REGS1_k127_8082006_20	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000006472	258.0
REGS1_k127_8082006_21	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	K01703,K20452	-	4.2.1.33,4.2.1.35,4.2.1.85	0.0000000000000000000000000000000000000000000000000000000000000000000002304	263.0
REGS1_k127_8082006_22	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	K00684	-	2.3.2.6	0.00000000000000000000000000000000000000000000000000000000000000005311	229.0
REGS1_k127_8082006_23	Memo-like protein	K06990	-	-	0.000000000000000000000000000000000000000000000000000000000445	212.0
REGS1_k127_8082006_24	PBS lyase HEAT-like repeat	-	-	-	0.00000000000000000000000000000000000000000000000000000002625	210.0
REGS1_k127_8082006_25	Belongs to the UPF0312 family	-	-	-	0.0000000000000000000000000000000000000000000000000000001322	201.0
REGS1_k127_8082006_26	-	-	-	-	0.00000000000000000000000000000000000000000000000000001637	208.0
REGS1_k127_8082006_27	Sigma-70, region 4	K03088	-	-	0.00000000000000000000000000000000000000000000000000003239	209.0
REGS1_k127_8082006_28	Protein of unknown function (DUF1223)	-	-	-	0.0000000000000000000000000000000000000000000000000003609	194.0
REGS1_k127_8082006_29	Male sterility protein	K15891	-	1.1.1.354	0.0000000000000000000000000000000000000000000000000006357	206.0
REGS1_k127_8082006_3	aminopeptidase activity	K07004	-	-	2.723e-230	736.0
REGS1_k127_8082006_30	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	K03787	-	3.1.3.5	0.000000000000000000000000000000000000000000000000002521	192.0
REGS1_k127_8082006_31	ApaG domain	K06195	-	-	0.0000000000000000000000000000000000000000000000921	173.0
REGS1_k127_8082006_32	Ferredoxin	K04755	-	-	0.0000000000000000000000000000000000000000000004522	171.0
REGS1_k127_8082006_33	PFAM AMMECR1 domain protein	K09141	-	-	0.000000000000000000000000000000000000000000001363	175.0
REGS1_k127_8082006_34	S1 P1 Nuclease	-	-	-	0.00000000000000000000000000000000000000002383	164.0
REGS1_k127_8082006_35	Belongs to the small heat shock protein (HSP20) family	K13993	-	-	0.00000000000000000000000000000000000000005088	156.0
REGS1_k127_8082006_36	Hsp20/alpha crystallin family	K13993	-	-	0.0000000000000000000000000000000000000253	148.0
REGS1_k127_8082006_37	Belongs to the UPF0301 (AlgH) family	K07735	-	-	0.0000000000000000000000000000000001162	143.0
REGS1_k127_8082006_4	ATPase activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777	625.0
REGS1_k127_8082006_40	Belongs to the eIF-2B alpha beta delta subunits family	K03680	-	-	0.00000000000000004569	90.0
REGS1_k127_8082006_41	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	K01704	-	4.2.1.33,4.2.1.35	0.000000000000004157	89.0
REGS1_k127_8082006_42	-	-	-	-	0.000000000003744	79.0
REGS1_k127_8082006_43	Matrixin	-	-	-	0.00000000002872	76.0
REGS1_k127_8082006_44	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	K02435	-	6.3.5.6,6.3.5.7	0.00000001312	61.0
REGS1_k127_8082006_45	Mitochondrial K+-H+ exchange-related	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006839,GO:0008150,GO:0009987,GO:0015672,GO:0016020,GO:0016021,GO:0019866,GO:0030001,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031975,GO:0032592,GO:0034220,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098573,GO:0098655,GO:0098660,GO:0098662,GO:0140141,GO:1990542	-	0.0006342	51.0
REGS1_k127_8082006_5	Acetyl xylan esterase (AXE1)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054	561.0
REGS1_k127_8082006_6	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	K02433	-	6.3.5.6,6.3.5.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654	556.0
REGS1_k127_8082006_7	TIGRFAM amidase, hydantoinase carbamoylase	K02083,K06016,K18151	-	3.5.1.116,3.5.1.6,3.5.1.87,3.5.3.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094	526.0
REGS1_k127_8082006_8	Polysaccharide biosynthesis protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334	487.0
REGS1_k127_8082006_9	Protein conserved in bacteria	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104	463.0
REGS1_k127_8092036_0	Sortilin, neurotensin receptor 3,	-	-	-	0.0	1188.0
REGS1_k127_8092036_1	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	K00325	-	1.6.1.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000001222	263.0
REGS1_k127_8092036_2	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000001904	242.0
REGS1_k127_8092036_3	DNA alkylation repair enzyme	-	-	-	0.00000000000000000000000000000000000000000000000000000000006433	211.0
REGS1_k127_8092036_4	Protein of unknown function (DUF1569)	-	-	-	0.00000000000000000000000253	108.0
REGS1_k127_8096655_0	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	1.773e-214	692.0
REGS1_k127_8096655_1	Heavy metal translocating P-type atpase	K01534	-	3.6.3.3,3.6.3.5	1.695e-199	651.0
REGS1_k127_8096655_10	Alanyl-tRNA synthetase	K01872	-	6.1.1.7	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002181	291.0
REGS1_k127_8096655_11	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	K04068,K10026	-	1.97.1.4,4.3.99.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000004844	274.0
REGS1_k127_8096655_12	D-Ala-D-Ala carboxypeptidase 3 (S13) family	K07259	-	3.4.16.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000008986	279.0
REGS1_k127_8096655_13	ABC-2 family transporter protein	K01992	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000764	259.0
REGS1_k127_8096655_14	Protein of unknown function DUF72	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001242	262.0
REGS1_k127_8096655_15	Protein of unknown function (DUF2400)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000001116	269.0
REGS1_k127_8096655_16	Glycosyl transferase, family 2	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000002767	246.0
REGS1_k127_8096655_17	PFAM Glycosyl transferase, group 1	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000004545	258.0
REGS1_k127_8096655_18	Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily	K02825	-	2.4.2.9	0.00000000000000000000000000000000000000000000000000000000000000002909	234.0
REGS1_k127_8096655_19	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	K01591	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	0.000000000000000000000000000000000000000000000000000000000003119	221.0
REGS1_k127_8096655_2	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	K01465	-	3.5.2.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883	478.0
REGS1_k127_8096655_20	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	K06173	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	0.00000000000000000000000000000000000000000000000000000000001323	224.0
REGS1_k127_8096655_21	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	K00762	-	2.4.2.10	0.000000000000000000000000000000000000000000000000000001763	204.0
REGS1_k127_8096655_22	Outer membrane efflux protein	K12340	-	-	0.0000000000000000000000000000000000000000000000000006391	213.0
REGS1_k127_8096655_23	Oxidoreductase NAD-binding domain	K02823	-	-	0.0000000000000000000000000000000000000000000000001071	188.0
REGS1_k127_8096655_24	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	K01142,K10773	-	3.1.11.2,4.2.99.18	0.000000000000000000000000000000000000002841	149.0
REGS1_k127_8096655_25	OmpA family	K03640	-	-	0.00000000000000000000000000000000000003855	151.0
REGS1_k127_8096655_26	Domain of unknown function (DUF4340)	-	-	-	0.00000000000000000000000000000000001999	154.0
REGS1_k127_8096655_27	transcriptional regulator	K21903	-	-	0.00000000000000000000000000000005808	130.0
REGS1_k127_8096655_28	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	0.0000000000000000000000000000002799	141.0
REGS1_k127_8096655_29	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	K01802,K03767,K03768	-	5.2.1.8	0.0000000000000000000000000002865	121.0
REGS1_k127_8096655_3	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	K00609	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219	394.0
REGS1_k127_8096655_30	PFAM glutaredoxin 2	-	-	-	0.00000000000000006969	85.0
REGS1_k127_8096655_31	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	K00762	-	2.4.2.10	0.00000000000009022	79.0
REGS1_k127_8096655_32	Belongs to the CDS family	K00981	-	2.7.7.41	0.00000000002162	73.0
REGS1_k127_8096655_33	ArsC family	K00537	-	1.20.4.1	0.0000000001549	65.0
REGS1_k127_8096655_34	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000009888	64.0
REGS1_k127_8096655_36	Heat shock 70 kDa protein	K04043	-	-	0.0001912	53.0
REGS1_k127_8096655_37	response regulator	K07814	-	-	0.0009088	51.0
REGS1_k127_8096655_4	ABC transporter	K01990	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119	373.0
REGS1_k127_8096655_5	Dihydroorotate dehydrogenase	K00226,K17828	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.98.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039	340.0
REGS1_k127_8096655_6	ABC-type uncharacterized transport system	K01992	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062	331.0
REGS1_k127_8096655_7	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	K00806	-	2.5.1.31	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867	298.0
REGS1_k127_8096655_8	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	K06920	-	6.3.4.20	0.000000000000000000000000000000000000000000000000000000000000000000000000000000003052	276.0
REGS1_k127_8096655_9	PFAM asparagine synthase	K06864	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000006584	279.0
REGS1_k127_8123858_0	DNA polymerase LigD, ligase domain	K01971	-	6.5.1.1	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306	406.0
REGS1_k127_8123858_1	Zn-dependent protease with chaperone function	K03799,K06013	-	3.4.24.84	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367	391.0
REGS1_k127_8123858_2	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	K01834	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293	348.0
REGS1_k127_8123858_3	AAA domain	K02450,K12283	-	-	0.000000000000000000000000000000000000000000000000000000000000004057	235.0
REGS1_k127_8123858_4	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	K10979	-	-	0.00000000000000000000000000000000000000000000000000004588	199.0
REGS1_k127_8123858_5	Homoserine dehydrogenase	K00003,K12524	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	0.0000000000000000000000000000000000000000000000000001083	202.0
REGS1_k127_8123858_6	Ferredoxin	-	-	-	0.00000000000000000000000000000000005323	137.0
REGS1_k127_8126394_0	xaa-pro aminopeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957	546.0
REGS1_k127_8126394_1	Amino acid permease	K03294	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449	405.0
REGS1_k127_8126394_2	Cys/Met metabolism PLP-dependent enzyme	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000001697	258.0
REGS1_k127_8126394_3	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	-	0.0000000000000000000000000000000000000000000000000000000000005623	216.0
REGS1_k127_8126394_4	PFAM PEBP family protein	K06910	-	-	0.0000000000000000000000000000000000000000000000000000004159	200.0
REGS1_k127_8126394_5	Domain of unknown function (DUF4342)	-	-	-	0.00000000000000001687	85.0
REGS1_k127_8126394_6	two component, sigma54 specific, transcriptional regulator, Fis family	K07713	-	-	0.00005141	54.0
REGS1_k127_8135530_0	Bacterial regulatory protein, Fis family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769	314.0
REGS1_k127_8135530_1	Bacterial regulatory protein, Fis family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012	296.0
REGS1_k127_8135530_2	radical SAM domain protein	-	-	-	0.00000000000000000000000000000000000000000001393	174.0
REGS1_k127_8135530_3	Domain of unknown function DUF302	-	-	-	0.000000000000000000000000000000000008634	140.0
REGS1_k127_8135530_4	Transcriptional regulator, Crp Fnr family	-	-	-	0.00000000000000000000000000000000009111	143.0
REGS1_k127_8135530_5	NifU-like domain	-	-	-	0.0000000000000000006906	89.0
REGS1_k127_8215731_0	Belongs to the PEP-utilizing enzyme family	K01007	-	2.7.9.2	0.0	1180.0
REGS1_k127_8215731_1	Zinc carboxypeptidase	K14054	-	-	0.0	1177.0
REGS1_k127_8215731_2	Response regulator, receiver	K01007	-	2.7.9.2	0.0	1102.0
REGS1_k127_8215731_3	glutamate dehydrogenase [NAD(P)+] activity	K00260,K00261,K00262	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	3.528e-214	670.0
REGS1_k127_8215731_4	MacB-like periplasmic core domain	-	-	-	2.137e-201	654.0
REGS1_k127_8215731_5	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	K01007	-	2.7.9.2	1.23e-199	641.0
REGS1_k127_8215731_6	metallophosphoesterase	K07096	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889	324.0
REGS1_k127_8215731_7	FRG	-	-	-	0.00000000000000000000001793	111.0
REGS1_k127_8230178_0	glutamate dehydrogenase [NAD(P)+] activity	K00262	-	1.4.1.4	1.424e-247	769.0
REGS1_k127_8230178_1	Ribosomal protein S1	K02945,K03527,K07571	-	1.17.7.4	1.79e-207	661.0
REGS1_k127_8230178_10	Belongs to the P(II) protein family	K04751	-	-	0.0000000000000000000000001262	109.0
REGS1_k127_8230178_11	-	-	-	-	0.0000000000000003741	88.0
REGS1_k127_8230178_2	Dehydrogenase	K00248,K09478	-	1.3.8.1,1.3.99.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685	541.0
REGS1_k127_8230178_3	Aminotransferase	K14267,K14287	-	2.6.1.17,2.6.1.88	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465	553.0
REGS1_k127_8230178_4	Acyl-CoA dehydrogenase, C-terminal domain	K18244	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843	309.0
REGS1_k127_8230178_5	PFAM Histidine triad (HIT) protein	K19710	-	2.7.7.53	0.000000000000000000000000000000000000000000000000001821	192.0
REGS1_k127_8230178_6	Belongs to the cytidylate kinase family. Type 1 subfamily	K00945	-	2.7.4.25	0.0000000000000000000000000000000000000000000000002473	186.0
REGS1_k127_8230178_7	Alpha/beta hydrolase family	-	-	-	0.00000000000000000000000000000000001421	144.0
REGS1_k127_8230178_8	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	K05788	-	-	0.00000000000000000000000000000000004567	141.0
REGS1_k127_8230178_9	oxidoreductase activity	-	-	-	0.00000000000000000000000000004052	137.0
REGS1_k127_8249291_0	leucyl-tRNA aminoacylation	K01869	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	6.719e-316	989.0
REGS1_k127_8249291_1	4Fe-4S dicluster domain	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075	472.0
REGS1_k127_8249291_2	Electron transfer flavoprotein FAD-binding domain	K03522	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864	341.0
REGS1_k127_8249291_3	Histone deacetylase domain	K04768	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764	304.0
REGS1_k127_8249291_4	Alpha beta hydrolase	K00433	-	1.11.1.10	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416	288.0
REGS1_k127_8249291_5	Domain of unknown function (DUF374)	K09778	-	-	0.00000000000000000000000000000000000004072	152.0
REGS1_k127_8249291_6	-	-	-	-	0.00000000000000000000000004844	109.0
REGS1_k127_8249291_7	Evidence 5 No homology to any previously reported sequences	K03643	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	0.000000000000000001545	94.0
REGS1_k127_8249291_8	-	-	-	-	0.00000000000001822	79.0
REGS1_k127_8258706_0	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	K01599	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189	434.0
REGS1_k127_8258706_1	CarboxypepD_reg-like domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348	394.0
REGS1_k127_8258706_2	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	K00231	-	1.3.3.15,1.3.3.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001	369.0
REGS1_k127_8258706_3	Arginase family	K01476	-	3.5.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105	351.0
REGS1_k127_8258706_4	Uncharacterized membrane protein (DUF2298)	-	-	-	0.00000000000000000006501	104.0
REGS1_k127_8258706_5	TIGRFAM VWFA-related Acidobacterial domain	-	-	-	0.0000000000000000001921	102.0
REGS1_k127_8258706_6	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	0.00000000000007476	83.0
REGS1_k127_8258706_7	Transcriptional regulatory protein, C terminal	K07671	-	-	0.0000002927	57.0
REGS1_k127_8396252_0	AcrB/AcrD/AcrF family	K03296	-	-	0.0	1485.0
REGS1_k127_8396252_1	cellulose binding	-	-	-	0.0	1388.0
REGS1_k127_8396252_10	Protein of unknown function (DUF2891)	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216	538.0
REGS1_k127_8396252_11	efflux transmembrane transporter activity	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196	544.0
REGS1_k127_8396252_12	efflux transmembrane transporter activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256	540.0
REGS1_k127_8396252_13	PFAM Aminotransferase class I and II	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151	508.0
REGS1_k127_8396252_14	Cleaves the N-terminal amino acid of tripeptides	K01258	-	3.4.11.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276	456.0
REGS1_k127_8396252_15	Outer membrane efflux protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912	380.0
REGS1_k127_8396252_16	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622	383.0
REGS1_k127_8396252_17	Endonuclease/Exonuclease/phosphatase family	K01142	-	3.1.11.2	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856	355.0
REGS1_k127_8396252_18	outer membrane efflux protein	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741	366.0
REGS1_k127_8396252_19	ABC-type multidrug transport system ATPase and permease	K06147,K06148	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988	365.0
REGS1_k127_8396252_2	lysine biosynthetic process via aminoadipic acid	-	-	-	4.209e-260	824.0
REGS1_k127_8396252_20	YVTN family beta-propeller repeat	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901	307.0
REGS1_k127_8396252_21	Biotin-lipoyl like	K03543	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007357	316.0
REGS1_k127_8396252_22	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004531	288.0
REGS1_k127_8396252_23	Transcriptional regulatory protein, C terminal	K07669	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000009232	269.0
REGS1_k127_8396252_24	SpoU rRNA Methylase family	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000001007	235.0
REGS1_k127_8396252_25	RNA pseudouridylate synthase	K06178,K06181	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.20,5.4.99.22	0.00000000000000000000000000000000000000000000000000005806	196.0
REGS1_k127_8396252_26	-	-	-	-	0.00000000000000000000000000000000000000000000000001173	188.0
REGS1_k127_8396252_27	efflux transmembrane transporter activity	-	-	-	0.000000000000000000000000000000000000000000001167	179.0
REGS1_k127_8396252_28	-	-	-	-	0.0000000000000000000000000000000000000000124	164.0
REGS1_k127_8396252_29	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	0.0000000000000000000009136	102.0
REGS1_k127_8396252_3	Peptidase family M28	-	-	-	4.405e-218	696.0
REGS1_k127_8396252_30	YsiA-like protein, C-terminal region	K09017	-	-	0.000000000000002597	83.0
REGS1_k127_8396252_32	MacB-like periplasmic core domain	-	-	-	0.000000001824	65.0
REGS1_k127_8396252_4	Peptidase family M13	K07386	-	-	8.473e-214	688.0
REGS1_k127_8396252_5	TIGRFAM drug resistance transporter, EmrB QacA subfamily	K03446	-	-	1.055e-208	662.0
REGS1_k127_8396252_6	SMART Elongator protein 3 MiaB NifB	-	-	-	1.328e-207	657.0
REGS1_k127_8396252_7	Amidase	K01426,K02433	-	3.5.1.4,6.3.5.6,6.3.5.7	4.594e-203	646.0
REGS1_k127_8396252_8	Sodium:solute symporter family	K03307	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594	565.0
REGS1_k127_8396252_9	efflux transmembrane transporter activity	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847	586.0
REGS1_k127_8429239_0	Sortilin, neurotensin receptor 3,	-	-	-	0.0	1301.0
REGS1_k127_8429239_1	ammonia-lyase activity	K01745	-	4.3.1.3	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172	584.0
REGS1_k127_8429239_2	Phospholipase B	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957	525.0
REGS1_k127_8429239_3	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822	406.0
REGS1_k127_8440754_0	Dipeptidyl peptidase IV (DPP IV)	K01278	-	3.4.14.5	6.074e-302	944.0
REGS1_k127_8440754_1	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	K00412	-	-	1.571e-270	860.0
REGS1_k127_8440754_10	Succinylglutamate desuccinylase / Aspartoacylase family	K06987	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858	329.0
REGS1_k127_8440754_11	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	K02257	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182	314.0
REGS1_k127_8440754_12	Sulfite exporter TauE/SafE	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743	300.0
REGS1_k127_8440754_13	amino acid-binding ACT domain protein	K04518	-	4.2.1.51	0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824	278.0
REGS1_k127_8440754_14	PFAM 2Fe-2S -binding	K03518,K07302,K13483	-	1.2.5.3,1.3.99.16	0.00000000000000000000000000000000000000000000000000000000000001186	219.0
REGS1_k127_8440754_15	4Fe-4S dicluster domain	-	-	-	0.0000000000000000000000000000000000000000005671	175.0
REGS1_k127_8440754_16	AI-2E family transporter	-	-	-	0.0000000000000000000000000000000000001716	154.0
REGS1_k127_8440754_17	proteolysis	-	-	-	0.00000000000000000000000000000000001764	153.0
REGS1_k127_8440754_18	Uncharacterized ACR, COG1430	K09005	-	-	0.00000000000000000000003181	104.0
REGS1_k127_8440754_19	Acetyltransferase (GNAT) domain	-	-	-	0.000000000000007137	85.0
REGS1_k127_8440754_2	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	K11177	-	1.17.1.4	3.171e-262	835.0
REGS1_k127_8440754_20	PFAM Rieske 2Fe-2S	-	-	-	0.00000000000000874	79.0
REGS1_k127_8440754_21	PFAM IS1 transposase	-	-	-	0.00000000000002322	74.0
REGS1_k127_8440754_22	-	-	-	-	0.00000000000009695	80.0
REGS1_k127_8440754_24	Belongs to the UPF0312 family	-	-	-	0.00000004536	66.0
REGS1_k127_8440754_25	Endonuclease/Exonuclease/phosphatase family	-	-	-	0.00000839	48.0
REGS1_k127_8440754_26	hydrolase activity, acting on ester bonds	K05714,K10623	-	3.7.1.14	0.0002177	44.0
REGS1_k127_8440754_3	PFAM UBA THIF-type NAD FAD binding	K21147	-	2.7.7.80,2.8.1.11	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559	576.0
REGS1_k127_8440754_4	Acetamidase/Formamidase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371	432.0
REGS1_k127_8440754_5	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046	445.0
REGS1_k127_8440754_6	sigma54 specific, transcriptional regulator, Fis family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782	407.0
REGS1_k127_8440754_7	Belongs to the cysteine synthase cystathionine beta- synthase family	K12339,K21148	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105	392.0
REGS1_k127_8440754_8	Polyphosphate kinase 2 (PPK2)	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125	387.0
REGS1_k127_8440754_9	FAD dependent oxidoreductase	K00303	-	1.5.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437	344.0
REGS1_k127_8447195_0	Peptidase M14, carboxypeptidase A	-	-	-	0.0	1048.0
REGS1_k127_8447195_1	FAD dependent oxidoreductase	K00111	-	1.1.5.3	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795	341.0
REGS1_k127_8447195_2	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	K01778	-	5.1.1.7	0.000000000000000000000000000000000000000000000000007891	191.0
REGS1_k127_8447195_3	Methyltransferase domain	-	-	-	0.000000000000000000000104	107.0
REGS1_k127_8466559_0	Hydrolase CocE NonD family	-	-	-	2.8e-322	996.0
REGS1_k127_8466559_1	peptidyl-tyrosine sulfation	-	-	-	0.00000000005399	76.0
REGS1_k127_8469951_0	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	1.864e-264	832.0
REGS1_k127_8469951_1	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	1.494e-233	743.0
REGS1_k127_8469951_10	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	0.000000000000000000000000000004355	124.0
REGS1_k127_8469951_11	Stress-induced bacterial acidophilic repeat motif	-	-	-	0.0000000000002431	74.0
REGS1_k127_8469951_12	-	-	-	-	0.0000000003583	67.0
REGS1_k127_8469951_13	Tetratricopeptide repeat	-	-	-	0.0000606	52.0
REGS1_k127_8469951_14	-	-	-	-	0.0001902	54.0
REGS1_k127_8469951_2	Elongator protein 3, MiaB family, Radical SAM	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936	544.0
REGS1_k127_8469951_3	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861	488.0
REGS1_k127_8469951_4	ATP-grasp domain	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886	371.0
REGS1_k127_8469951_5	POT family	K03305	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958	357.0
REGS1_k127_8469951_6	DNA ligase	K01971	-	6.5.1.1	0.0000000000000000000000000000000000000000000000000000000002266	211.0
REGS1_k127_8469951_7	DinB family	-	-	-	0.0000000000000000000000000000000000000001334	156.0
REGS1_k127_8469951_8	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	0.00000000000000000000000000000000000000171	166.0
REGS1_k127_8469951_9	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	0.0000000000000000000000000000006613	128.0
REGS1_k127_851_0	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	K01895	-	6.2.1.1	4.863e-299	929.0
REGS1_k127_851_1	Type II IV secretion system protein	K02454,K02652	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149	507.0
REGS1_k127_851_2	ABC transporter	K02003	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094	354.0
REGS1_k127_851_3	diguanylate cyclase	-	-	-	0.00000000000000000009824	102.0
REGS1_k127_851_4	Tetratricopeptide repeat	-	-	-	0.00000000002576	74.0
REGS1_k127_851_5	PFAM heat shock protein DnaJ domain protein	-	-	-	0.000000002064	67.0
REGS1_k127_85668_0	-	-	-	-	0.0	1693.0
REGS1_k127_85668_1	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382	382.0
REGS1_k127_85668_2	Winged helix DNA-binding domain	K09927	-	-	0.0000000000000000000000000000000000000000000000000000000000000001541	237.0
REGS1_k127_85668_3	-	-	-	-	0.0000000000000000000000000000000000000002792	158.0
REGS1_k127_85668_4	PFAM cobalamin B12-binding domain protein	K01849	-	5.4.99.2	0.00000000001504	66.0
REGS1_k127_85668_5	oxidoreductase	-	-	-	0.00007719	51.0
REGS1_k127_8609219_0	serine-type peptidase activity	-	-	-	0.0	1148.0
REGS1_k127_8609219_1	gamma-glutamyltransferase	K00681	-	2.3.2.2,3.4.19.13	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461	578.0
REGS1_k127_8609219_10	Molybdate ABC transporter	K02018	-	-	0.000000000000000000000000000000000000000000000000000000000000003214	228.0
REGS1_k127_8609219_11	ATPases associated with a variety of cellular activities	-	-	-	0.00000000000000000000000000000000000000000000000000000000007457	211.0
REGS1_k127_8609219_12	ABC transporter, phosphonate, periplasmic substrate-binding protein	K02020	-	-	0.00000000000000000000000000000000000000000000000000000008399	204.0
REGS1_k127_8609219_13	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	K02501	-	-	0.0000000000000000000000000000000000000000000000000006803	199.0
REGS1_k127_8609219_14	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	K11755	-	3.5.4.19,3.6.1.31	0.00000000000000000000000000000000003952	138.0
REGS1_k127_8609219_15	TOBE domain	-	-	-	0.00000000000000000000000000211	124.0
REGS1_k127_8609219_16	Domain of unknown function (DUF1905)	-	-	-	0.000000000000000000001404	104.0
REGS1_k127_8609219_2	COG1228 Imidazolonepropionase and related	K01443	-	3.5.1.25	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643	566.0
REGS1_k127_8609219_3	ATP phosphoribosyltransferase	K00765	-	2.4.2.17	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016	407.0
REGS1_k127_8609219_4	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	K00013	-	1.1.1.23	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018	355.0
REGS1_k127_8609219_5	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	K02500	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000204	289.0
REGS1_k127_8609219_6	Amidohydrolase family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002617	287.0
REGS1_k127_8609219_7	Imidazoleglycerol-phosphate dehydratase	K01693	-	4.2.1.19	0.000000000000000000000000000000000000000000000000000000000000000000000000000489	275.0
REGS1_k127_8609219_8	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	K00817	-	2.6.1.9	0.000000000000000000000000000000000000000000000000000000000000000000000005311	268.0
REGS1_k127_8609219_9	Belongs to the HisA HisF family	K01814	-	5.3.1.16	0.00000000000000000000000000000000000000000000000000000000000000004776	229.0
REGS1_k127_8619020_0	PFAM Peptidase M20	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549	522.0
REGS1_k127_8619020_1	Belongs to the peptidase S11 family	K01286,K07258,K07262	GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564	3.4.16.4	0.0000000000000000000000000000000000000000007853	171.0
REGS1_k127_8619020_2	Necessary for formate dehydrogenase activity	K02380	-	-	0.0000000000000000000232	102.0
REGS1_k127_8619020_3	TonB-dependent Receptor Plug Domain	-	-	-	0.0000000000001988	78.0
REGS1_k127_8619020_4	Glutaredoxin	-	-	-	0.00000001528	63.0
REGS1_k127_8631550_0	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	K12573	-	-	1.269e-202	664.0
REGS1_k127_8631550_1	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	K02434	-	6.3.5.6,6.3.5.7	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592	480.0
REGS1_k127_8631550_10	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	K02005	-	-	0.000000000000000000000000000000000000000000000000001953	200.0
REGS1_k127_8631550_11	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	K09811,K09812	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531	-	0.000000000000000000000000000000000000005615	157.0
REGS1_k127_8631550_12	Stage II sporulation protein	K06381	-	-	0.000000000000000000000000000000001419	149.0
REGS1_k127_8631550_13	von Willebrand factor, type A	K07114	-	-	0.000000000000000000000003048	117.0
REGS1_k127_8631550_14	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.0000000000000000000003912	104.0
REGS1_k127_8631550_15	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	K01610	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	0.0000000000000004065	83.0
REGS1_k127_8631550_16	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	K01610	-	4.1.1.49	0.0000000000003039	74.0
REGS1_k127_8631550_17	mttA/Hcf106 family	K03116	-	-	0.0000000000003665	72.0
REGS1_k127_8631550_18	Heat induced stress protein YflT	-	-	-	0.000000001609	66.0
REGS1_k127_8631550_19	Heavy-metal resistance	-	-	-	0.00000003001	61.0
REGS1_k127_8631550_2	Elongation factor SelB, winged helix	K03833	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382	458.0
REGS1_k127_8631550_20	TIGRFAM geranylgeranyl reductase	-	-	-	0.0001288	50.0
REGS1_k127_8631550_3	LytB protein	K03527	-	1.17.7.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768	442.0
REGS1_k127_8631550_4	response regulator	K07713	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083	366.0
REGS1_k127_8631550_5	PFAM MOFRL domain protein	K11529	-	2.7.1.165	0.00000000000000000000000000000000000000000000000000000000000000000000000000000002706	285.0
REGS1_k127_8631550_6	Cell division ATP-binding protein ftsE	K09811,K09812	GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531	-	0.000000000000000000000000000000000000000000000000000000000000000000000000007472	259.0
REGS1_k127_8631550_7	Sigma-54 interaction domain	K07715,K10126	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000557	268.0
REGS1_k127_8631550_8	HD domain	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000002332	259.0
REGS1_k127_8631550_9	Outer membrane efflux protein	K12340	-	-	0.000000000000000000000000000000000000000000000000000000000000001257	242.0
REGS1_k127_8656935_0	peptidase S9 prolyl oligopeptidase active site	-	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	6.764e-297	936.0
REGS1_k127_8656935_1	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	K03544	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868	550.0
REGS1_k127_8656935_10	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	0.000000000000000793	92.0
REGS1_k127_8656935_11	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	K03832	-	-	0.0002117	51.0
REGS1_k127_8656935_12	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	K03545	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	0.0009593	44.0
REGS1_k127_8656935_2	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955	539.0
REGS1_k127_8656935_3	Lamin Tail Domain	K07004	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055	516.0
REGS1_k127_8656935_4	Rhomboid family	K07059	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797	346.0
REGS1_k127_8656935_5	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	K01358	-	3.4.21.92	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935	297.0
REGS1_k127_8656935_6	TRAP transporter T-component	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000001739	258.0
REGS1_k127_8656935_7	peroxidase activity	K00435	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000004348	249.0
REGS1_k127_8656935_8	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	K03545	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	0.000000000000000000000000000000000000000000000000000000000000000001446	244.0
REGS1_k127_8656935_9	carbohydrate transport	K11688,K21395	-	-	0.0000000000000000000000000000000000000000000000000000000000000001216	236.0
REGS1_k127_8703209_0	Sortilin, neurotensin receptor 3,	-	-	-	1.061e-317	998.0
REGS1_k127_8703209_1	Insulinase (Peptidase family M16)	K07263	-	-	1.438e-278	887.0
REGS1_k127_8703209_10	Sodium:solute symporter family	-	-	-	0.0000000000000000000000000000000000000000000000000007094	189.0
REGS1_k127_8703209_11	Belongs to the aspartate-semialdehyde dehydrogenase family	K00133	-	1.2.1.11	0.0000000000000000000000000000000000000000002835	164.0
REGS1_k127_8703209_12	Histidine kinase	-	-	-	0.00000000005586	67.0
REGS1_k127_8703209_2	Penicillin amidase	K01434,K07116	-	3.5.1.11,3.5.1.97	6.907e-258	813.0
REGS1_k127_8703209_3	PFAM D-aminoacylase, C-terminal region	K06015	-	3.5.1.81	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232	476.0
REGS1_k127_8703209_4	Belongs to the aspartokinase family	K00928	-	2.7.2.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803	392.0
REGS1_k127_8703209_5	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	K01714	-	4.3.3.7	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468	379.0
REGS1_k127_8703209_6	Belongs to the transferase hexapeptide repeat family	K00674	-	2.3.1.117	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002	331.0
REGS1_k127_8703209_7	Peptidase dimerisation domain	K01438	-	3.5.1.16	0.00000000000000000000000000000000000000000000000000000000000000000000000000000001369	289.0
REGS1_k127_8703209_8	Belongs to the aspartate-semialdehyde dehydrogenase family	K00133	-	1.2.1.11	0.00000000000000000000000000000000000000000000000000000000000000000000000000000004663	273.0
REGS1_k127_8703209_9	Belongs to the DapB family	K00215	-	1.17.1.8	0.00000000000000000000000000000000000000000000000000000000000007575	228.0
REGS1_k127_8774063_0	cellulose binding	-	-	-	0.0	1276.0
REGS1_k127_8774063_1	Glycogen debranching enzyme	-	-	-	2.505e-223	735.0
REGS1_k127_8774063_10	Acetyltransferase (GNAT) family	-	-	-	0.000000000000000000000000000000000000000000000000000000000000006125	222.0
REGS1_k127_8774063_11	acetyltransferase	-	-	-	0.000000000000000000000000000000000000000000001611	175.0
REGS1_k127_8774063_12	Thioesterase superfamily	-	-	-	0.0000000000000000000000000000000000000000000958	164.0
REGS1_k127_8774063_13	-	-	-	-	0.000000000000000000000009275	103.0
REGS1_k127_8774063_14	Peptidase family M48	-	-	-	0.000000000000001345	84.0
REGS1_k127_8774063_15	Cyclic phosphodiesterase-like protein	-	-	-	0.0000000000009367	76.0
REGS1_k127_8774063_16	SnoaL-like domain	-	-	-	0.00000001036	64.0
REGS1_k127_8774063_17	PFAM Methyltransferase type 11	-	-	-	0.0000005681	59.0
REGS1_k127_8774063_18	Bacterial regulatory protein, Fis family	-	-	-	0.00008589	53.0
REGS1_k127_8774063_2	MacB-like periplasmic core domain	-	-	-	5.431e-200	652.0
REGS1_k127_8774063_3	MacB-like periplasmic core domain	-	-	-	9.518e-196	638.0
REGS1_k127_8774063_4	efflux transmembrane transporter activity	K02004	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008	521.0
REGS1_k127_8774063_5	GMP synthase (glutamine-hydrolyzing) activity	K01951	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467	495.0
REGS1_k127_8774063_6	Ornithine cyclodeaminase/mu-crystallin family	K01750	-	4.3.1.12	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168	345.0
REGS1_k127_8774063_7	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	K07304	-	1.8.4.11	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329	322.0
REGS1_k127_8774063_8	Enoyl-(Acyl carrier protein) reductase	K15734	-	1.1.1.105	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743	291.0
REGS1_k127_8774063_9	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000005571	246.0
REGS1_k127_8824431_0	PFAM Radical SAM	-	-	-	1.599e-237	743.0
REGS1_k127_8824431_1	D-aminoacylase domain protein	K01465,K06015	-	3.5.1.81,3.5.2.3	2.059e-203	650.0
REGS1_k127_8824431_2	Pyridoxal-phosphate dependent enzyme	K01505,K05396	-	3.5.99.7,4.4.1.15	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197	489.0
REGS1_k127_8824431_3	fatty acid beta-oxidation using acyl-CoA dehydrogenase	K03522	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481	449.0
REGS1_k127_8824431_4	Belongs to the asparaginase 1 family	K01424	-	3.5.1.1	0.00000000000000000000000000000000000000000000000000000000000002244	240.0
REGS1_k127_8824431_5	electron transfer activity	K03521	-	-	0.000000000000000000000000000000000000000001944	157.0
REGS1_k127_8824431_6	Membrane dipeptidase (Peptidase family M19)	K01273	-	3.4.13.19	0.00000000000000000000000000000000000000002768	172.0
REGS1_k127_8824431_7	negative regulation of transcription, DNA-templated	-	-	-	0.00000000000000000000000000000000000001099	148.0
REGS1_k127_8824431_8	-	-	-	-	0.00000000000000000000000000002603	133.0
REGS1_k127_8964078_0	peptidase S9 prolyl oligopeptidase active site	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677	548.0
REGS1_k127_8964078_1	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	K01696	-	4.2.1.20	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896	534.0
REGS1_k127_8964078_10	nitrogen compound transport	K02033	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141	355.0
REGS1_k127_8964078_11	Coenzyme A transferase	K01028	-	2.8.3.5	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011	345.0
REGS1_k127_8964078_12	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	K00766,K13497	-	2.4.2.18,4.1.3.27	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791	330.0
REGS1_k127_8964078_13	Coenzyme A transferase	K01029	-	2.8.3.5	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333	323.0
REGS1_k127_8964078_14	PFAM transferase hexapeptide repeat containing protein	K00966	-	2.7.7.13	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365	316.0
REGS1_k127_8964078_15	SpoIVB peptidase S55	K00973,K02414,K21449	-	2.7.7.24	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025	311.0
REGS1_k127_8964078_16	16S rRNA methyltransferase RsmB/F	K03500	-	2.1.1.176	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002141	310.0
REGS1_k127_8964078_17	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	K00604	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	0.000000000000000000000000000000000000000000000000000000000000000000000000000000007133	286.0
REGS1_k127_8964078_18	Binding-protein-dependent transport system inner membrane component	K02034,K15582	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001887	262.0
REGS1_k127_8964078_19	Peptidase C26	K01658	-	4.1.3.27	0.00000000000000000000000000000000000000000000000000000000000000000000000007955	261.0
REGS1_k127_8964078_2	NeuB family	K03856	-	2.5.1.54	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145	490.0
REGS1_k127_8964078_20	response regulator	K07713	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000001012	279.0
REGS1_k127_8964078_21	Ribulose-phosphate 3 epimerase family	K01783	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	0.00000000000000000000000000000000000000000000000000000000000000000000008247	253.0
REGS1_k127_8964078_22	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	K13832	-	1.1.1.25,4.2.1.10	0.0000000000000000000000000000000000000000000000000000000000000000000006173	256.0
REGS1_k127_8964078_23	Tryptophan synthase alpha chain	K01695	-	4.2.1.20	0.0000000000000000000000000000000000000000000000000000000000000000006694	238.0
REGS1_k127_8964078_24	Indole-3-glycerol phosphate synthase	K01609	-	4.1.1.48	0.0000000000000000000000000000000000000000000000000001001	214.0
REGS1_k127_8964078_25	Belongs to the TrpF family	K01817	-	5.3.1.24	0.00000000000000000000000000000000000000000000000001364	187.0
REGS1_k127_8964078_26	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	K01462	-	3.5.1.88	0.00000000000000000000000000000000000000000000002969	178.0
REGS1_k127_8964078_27	Prephenate dehydrogenase	K04517	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12	0.0000000000000000000000000000000000000000003179	170.0
REGS1_k127_8964078_28	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	K00995	-	2.7.8.5	0.000000000000000000000000000000000000005675	166.0
REGS1_k127_8964078_29	surface antigen	-	-	-	0.000000000000000000000000000000003304	147.0
REGS1_k127_8964078_3	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	K01657	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667	489.0
REGS1_k127_8964078_30	thioesterase	K07107	-	-	0.00000000000000000000000000000006483	138.0
REGS1_k127_8964078_31	bacterial (prokaryotic) histone like domain	K03530	-	-	0.000000000000000000000000000001248	123.0
REGS1_k127_8964078_32	Belongs to the sigma-70 factor family. ECF subfamily	K03088	-	-	0.000000000000000000000000000001357	140.0
REGS1_k127_8964078_33	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	K05807	-	-	0.000000000000000000000000000001852	134.0
REGS1_k127_8964078_34	Chorismate mutase type II	K04093	-	5.4.99.5	0.000000000000000000001366	104.0
REGS1_k127_8964078_35	regulatory protein, MerR	-	-	-	0.0000000000000000000201	97.0
REGS1_k127_8964078_36	SMART Mov34 MPN PAD-1 family protein	K21140	-	3.13.1.6	0.00000000000000000005083	105.0
REGS1_k127_8964078_37	serine threonine protein kinase	K08884,K12132	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	0.0000000000000001274	89.0
REGS1_k127_8964078_38	oxidoreductase activity	-	-	-	0.0000000000000006619	92.0
REGS1_k127_8964078_39	Peptidoglycan-binding LysM	-	-	-	0.00003713	54.0
REGS1_k127_8964078_4	alpha beta alpha domain I	K01840	-	5.4.2.8	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149	470.0
REGS1_k127_8964078_40	Tetratricopeptide repeat	K03350	-	-	0.0003724	53.0
REGS1_k127_8964078_5	Belongs to the thiolase family	K00626	-	2.3.1.9	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934	447.0
REGS1_k127_8964078_6	-	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551	419.0
REGS1_k127_8964078_7	GTPase that plays an essential role in the late steps of ribosome biogenesis	K03977	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289	393.0
REGS1_k127_8964078_8	Polysaccharide biosynthesis protein	K01784,K08679	-	5.1.3.2,5.1.3.6	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353	385.0
REGS1_k127_8964078_9	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	K01736	-	4.2.3.5	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183	372.0
REGS1_k127_8974103_0	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	5.892e-204	643.0
REGS1_k127_8974103_1	Zinc carboxypeptidase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182	457.0
REGS1_k127_8974103_2	amino acid	K03294,K13868	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193	409.0
REGS1_k127_8974103_3	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	K00077	-	1.1.1.169	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903	347.0
REGS1_k127_8974103_4	DinB family	-	-	-	0.0000000000000000000000000000000000000000000000000000000402	203.0
REGS1_k127_8974103_5	Histidine phosphatase superfamily (branch 1)	-	-	-	0.000000000000000000001963	98.0
REGS1_k127_8974103_6	Sigma factor PP2C-like phosphatases	K07315	-	3.1.3.3	0.000001606	60.0
REGS1_k127_898947_0	Beta-lactamase	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623	537.0
REGS1_k127_898947_1	carboxylic acid catabolic process	K19802	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051	494.0
REGS1_k127_898947_2	arylsulfatase activity	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011	333.0
REGS1_k127_898947_3	NlpC P60 family protein	-	-	-	0.000000000000000000000000000000000000000000000000000000000000000000000000001947	267.0
REGS1_k127_898947_4	serine-type endopeptidase activity	-	-	-	0.0005948	42.0
REGS1_k127_8994819_0	elongation factor G	K02355	-	-	5.108e-227	723.0
REGS1_k127_8994819_1	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	K03076	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687	597.0
REGS1_k127_8994819_10	Belongs to the bacterial ribosomal protein bL36 family	K02919	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	0.00000000005532	68.0
REGS1_k127_8994819_2	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	K03040	-	2.7.7.6	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876	481.0
REGS1_k127_8994819_3	TIGRFAM methionine aminopeptidase, type I	K01265	-	3.4.11.18	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253	307.0
REGS1_k127_8994819_4	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	K02986	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001612	287.0
REGS1_k127_8994819_5	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	K00939	-	2.7.4.3	0.000000000000000000000000000000000000000000000000000001537	199.0
REGS1_k127_8994819_6	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	K02948	-	-	0.0000000000000000000000000000000000000000000000008131	179.0
REGS1_k127_8994819_7	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	K02952	-	-	0.00000000000000000000000000000000000000000000001391	173.0
REGS1_k127_8994819_8	Ribosomal protein L17	K02879	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	0.0000000000000000000000000000000000009297	146.0
REGS1_k127_8994819_9	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	K02518	-	-	0.00000000000000003609	85.0
REGS1_k127_906682_0	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	K02654	-	3.4.23.43	0.0000000000000000000000000000000000000000000000000000000000000000005864	250.0
REGS1_k127_906682_1	-	-	-	-	0.000000000000000000000000000000000000000000000000000000001306	210.0
REGS1_k127_906682_2	Histidine kinase	K02668,K07708	-	2.7.13.3	0.0000000000000000000000000000000000000000000001248	185.0
REGS1_k127_906682_3	peptidyl-tyrosine sulfation	-	-	-	0.000000000000000000000000000000000000000000006289	183.0
REGS1_k127_906682_4	Tfp pilus assembly protein tip-associated adhesin	K02674	-	-	0.0000000000000000000000000000002091	144.0
REGS1_k127_906682_5	TIGRFAM prepilin-type N-terminal cleavage methylation domain	K02246,K08084	-	-	0.0004705	50.0
REGS1_k127_906682_6	pilus assembly protein PilW	K02672	-	-	0.0006169	52.0
REGS1_k127_9174680_0	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	K01635	-	4.1.2.40	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187	479.0
REGS1_k127_9174680_1	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	K03151	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199	372.0
REGS1_k127_9174680_2	Squalene/phytoene synthase	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000005633	255.0
REGS1_k127_9174680_3	Squalene/phytoene synthase	K02291	-	2.5.1.32,2.5.1.99	0.0000000000000000000000000000000000000000000000000000000000000004327	229.0
REGS1_k127_9174680_4	squalene-associated FAD-dependent desaturase	K21677	-	1.17.8.1	0.0000000000000000000000000000000000000000000000000000000001211	228.0
REGS1_k127_9174680_5	peptide deformylase activity	K01462	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	0.0000000000000000000000000000000000000000000000000001051	192.0
REGS1_k127_9174680_6	NUDIX domain	K00077,K01092,K03574,K03795	-	1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3	0.0000000000000000000000000000000000000000000000001137	183.0
REGS1_k127_9193419_0	Peptidase family M3	K01284,K01414	-	3.4.15.5,3.4.24.70	8.901e-259	816.0
REGS1_k127_9193419_1	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	K01881	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	4.587e-202	640.0
REGS1_k127_9193419_10	PFAM glycosyl transferase family 2	-	-	-	0.0000000000000000000000000000000000000000000000005733	196.0
REGS1_k127_9193419_11	Tetratricopeptide repeat	-	-	-	0.000000000000000000000000000000000000000000381	178.0
REGS1_k127_9193419_12	PFAM glycosyl transferase family 2	-	-	-	0.00000000000000000000000000000000000000002209	173.0
REGS1_k127_9193419_13	Polysaccharide deacetylase	-	-	-	0.00000000000000000000000000000000000001469	166.0
REGS1_k127_9193419_14	ABC-2 type transporter	K09690	-	-	0.000000000000000000000000000000000333	142.0
REGS1_k127_9193419_15	Glycosyl transferase family group 2	K07011	-	-	0.000000000000000000000000000000001003	152.0
REGS1_k127_9193419_16	PFAM Glycosyl transferase, group 1	-	-	-	0.0000000000000000000000846	114.0
REGS1_k127_9193419_17	Uncharacterized conserved protein (DUF2304)	K09153	-	-	0.00000000000001079	78.0
REGS1_k127_9193419_18	Tetratricopeptide TPR_2 repeat protein	-	-	-	0.00000000000003301	83.0
REGS1_k127_9193419_19	Tfp pilus assembly protein, tip-associated adhesin PilY1	K02674	-	-	0.0004613	51.0
REGS1_k127_9193419_2	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459	461.0
REGS1_k127_9193419_3	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	K01735,K13829	-	2.7.1.71,4.2.3.4	0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476	319.0
REGS1_k127_9193419_4	Glycosyltransferase Family 4	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000001319	250.0
REGS1_k127_9193419_5	ABC transporter	K09691	-	-	0.0000000000000000000000000000000000000000000000000000000000006091	220.0
REGS1_k127_9193419_6	PFAM Nitroreductase	-	-	-	0.0000000000000000000000000000000000000000000000000000006981	199.0
REGS1_k127_9193419_7	Glycosyl transferase, family 2	-	-	-	0.00000000000000000000000000000000000000000000000000004961	213.0
REGS1_k127_9193419_8	Glycosyl transferase family 2	-	-	-	0.000000000000000000000000000000000000000000000000000204	210.0
REGS1_k127_9193419_9	Glycosyl transferase 4-like domain	-	-	-	0.00000000000000000000000000000000000000000000000001345	207.0
REGS1_k127_958602_0	ABC-type antimicrobial peptide transport system, permease component	-	-	-	3.046e-252	806.0
REGS1_k127_958602_1	MatE	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694	616.0
REGS1_k127_958602_10	Domain of unknown function (DUF4920)	-	-	-	0.0000000000000000004556	93.0
REGS1_k127_958602_11	efflux transmembrane transporter activity	-	-	-	0.0000000000000000006716	94.0
REGS1_k127_958602_12	Penicillin amidase	K01434	-	3.5.1.11	0.0000000000000005609	77.0
REGS1_k127_958602_13	subunit of a heme lyase	K02200	-	-	0.0000000007833	66.0
REGS1_k127_958602_2	major facilitator superfamily MFS_1	-	-	-	0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977	377.0
REGS1_k127_958602_3	-	-	-	-	0.00000000000000000000000000000000000000000000000000000000000000000000000001794	257.0
REGS1_k127_958602_4	H( )-stimulated, divalent metal cation uptake system	K03322	-	-	0.0000000000000000000000000000000000000000000000000000000000000000114	227.0
REGS1_k127_958602_5	Disulphide isomerase	-	-	-	0.000000000000000000000000000000000000000000000001533	179.0
REGS1_k127_958602_6	MacB-like periplasmic core domain	-	-	-	0.00000000000000000000000000000000000000000000001759	179.0
REGS1_k127_958602_7	Carboxypeptidase regulatory-like domain	-	-	-	0.0000000000000000000000000000000000000000000002734	192.0
REGS1_k127_958602_8	MacB-like periplasmic core domain	-	-	-	0.00000000000000000000000000001948	133.0
REGS1_k127_958602_9	-	-	-	-	0.000000000000000000003068	99.0

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