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Overview

ID MAG03313
Name REGS1_bin.5
Sample SMP0079
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Coriobacteriia
Order Anaerosomatales
Family PALSA-660
Genus JANYAK01
Species
Assembly information
Completeness (%) 95.06
Contamination (%) 0.85
GC content (%) 69.0
N50 (bp) 44,621
Genome size (bp) 1,947,998

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1755

Gene name Description KEGG GOs EC E-value Score Sequence
REGS1_k127_1016663_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 573.0
REGS1_k127_1016663_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 568.0
REGS1_k127_1016663_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
REGS1_k127_1016663_11 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002156 250.0
REGS1_k127_1016663_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
REGS1_k127_1016663_13 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000001237 239.0
REGS1_k127_1016663_14 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000003506 225.0
REGS1_k127_1016663_15 PFAM Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000000000000000000000000000000000005137 229.0
REGS1_k127_1016663_16 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000002366 223.0
REGS1_k127_1016663_17 pfam rok K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000003451 214.0
REGS1_k127_1016663_18 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000001262 200.0
REGS1_k127_1016663_19 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000003086 221.0
REGS1_k127_1016663_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 556.0
REGS1_k127_1016663_20 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000003297 214.0
REGS1_k127_1016663_21 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000168 204.0
REGS1_k127_1016663_22 PFAM Peptidase M23 K21471 - - 0.0000000000000000000000000000000000000000000000000002428 201.0
REGS1_k127_1016663_23 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000006695 173.0
REGS1_k127_1016663_24 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000001153 185.0
REGS1_k127_1016663_25 DUF218 domain - - - 0.0000000000000000000000000000000000000000009968 169.0
REGS1_k127_1016663_26 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000001341 166.0
REGS1_k127_1016663_27 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000004578 167.0
REGS1_k127_1016663_28 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000000000000866 146.0
REGS1_k127_1016663_29 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000000000104 148.0
REGS1_k127_1016663_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 481.0
REGS1_k127_1016663_30 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000006298 147.0
REGS1_k127_1016663_31 G5 domain protein - - - 0.000000000000000000000000000000000006379 151.0
REGS1_k127_1016663_32 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000002445 146.0
REGS1_k127_1016663_33 protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000007028 154.0
REGS1_k127_1016663_34 Flavodoxin-like fold - - - 0.0000000000000000000000000000001524 131.0
REGS1_k127_1016663_35 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000001703 136.0
REGS1_k127_1016663_36 Biofilm formation stimulator VEG - - - 0.000000000000000000000005637 104.0
REGS1_k127_1016663_37 Could be involved in septation K06412 - - 0.00000000000000000000007556 102.0
REGS1_k127_1016663_38 Regulators of stationary sporulation gene expression K06284 - - 0.000000000000000000003204 97.0
REGS1_k127_1016663_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 459.0
REGS1_k127_1016663_40 Zn peptidase - - - 0.0000001276 60.0
REGS1_k127_1016663_41 Domain of unknown function (DUF4870) - - - 0.000001099 55.0
REGS1_k127_1016663_43 - - - - 0.00005192 53.0
REGS1_k127_1016663_5 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 428.0
REGS1_k127_1016663_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 364.0
REGS1_k127_1016663_7 domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 293.0
REGS1_k127_1016663_8 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000001131 271.0
REGS1_k127_1016663_9 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
REGS1_k127_1286123_0 Belongs to the SEDS family - - - 4.84e-247 792.0
REGS1_k127_1286123_1 Anion-transporting ATPase K01551 - 3.6.3.16 1.713e-208 667.0
REGS1_k127_1286123_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 411.0
REGS1_k127_1286123_11 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 390.0
REGS1_k127_1286123_12 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 306.0
REGS1_k127_1286123_13 phosphatase 2C K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 299.0
REGS1_k127_1286123_14 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008291 283.0
REGS1_k127_1286123_15 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001058 278.0
REGS1_k127_1286123_16 ABC transporter, ATP-binding protein K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000214 275.0
REGS1_k127_1286123_17 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001143 274.0
REGS1_k127_1286123_18 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 270.0
REGS1_k127_1286123_19 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000162 274.0
REGS1_k127_1286123_2 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 533.0
REGS1_k127_1286123_20 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000462 264.0
REGS1_k127_1286123_21 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000117 259.0
REGS1_k127_1286123_22 Kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008081 267.0
REGS1_k127_1286123_23 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
REGS1_k127_1286123_24 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000002602 217.0
REGS1_k127_1286123_25 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000006375 222.0
REGS1_k127_1286123_26 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000004971 217.0
REGS1_k127_1286123_27 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001155 203.0
REGS1_k127_1286123_28 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000001568 207.0
REGS1_k127_1286123_29 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000003156 194.0
REGS1_k127_1286123_3 Magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 503.0
REGS1_k127_1286123_30 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000005275 170.0
REGS1_k127_1286123_31 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.0000000000000000000000000000000000000000005053 170.0
REGS1_k127_1286123_32 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000007143 155.0
REGS1_k127_1286123_33 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000001339 160.0
REGS1_k127_1286123_34 Protein of unknown function (DUF2662) - - - 0.000000000000000000000000000000000005415 147.0
REGS1_k127_1286123_35 Transcriptional regulatory protein, C terminal K02483,K07658,K07668 - - 0.00000000000000000000000000000005079 128.0
REGS1_k127_1286123_36 cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000004545 134.0
REGS1_k127_1286123_37 Domain of unknown function DUF302 - - - 0.000000000000000000000000000002577 132.0
REGS1_k127_1286123_38 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000000000009443 126.0
REGS1_k127_1286123_39 - - - - 0.00000000000000000000000000003869 128.0
REGS1_k127_1286123_4 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 487.0
REGS1_k127_1286123_40 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000001275 128.0
REGS1_k127_1286123_41 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000005133 116.0
REGS1_k127_1286123_42 FHA domain - - - 0.00000000000000000000009262 107.0
REGS1_k127_1286123_43 Redox-active disulfide protein - - - 0.00000000000000000001014 93.0
REGS1_k127_1286123_44 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000002103 91.0
REGS1_k127_1286123_45 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000002154 99.0
REGS1_k127_1286123_46 cell redox homeostasis K02199,K03671 - - 0.00000000000000000962 90.0
REGS1_k127_1286123_47 Protein of unknown function (DUF4446) - - - 0.00000000000001414 83.0
REGS1_k127_1286123_48 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000008586 72.0
REGS1_k127_1286123_49 Redoxin - - - 0.000000000006677 70.0
REGS1_k127_1286123_5 TIGRFAM Arsenical-resistance protein K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 461.0
REGS1_k127_1286123_50 Acetyltransferase (GNAT) domain - - - 0.000000000007767 74.0
REGS1_k127_1286123_51 - - - - 0.0000000003493 72.0
REGS1_k127_1286123_52 Helix-turn-helix domain - - - 0.00001226 56.0
REGS1_k127_1286123_53 Protein of unknown function (DUF2892) - - - 0.00005057 53.0
REGS1_k127_1286123_6 Kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
REGS1_k127_1286123_7 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 444.0
REGS1_k127_1286123_8 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 424.0
REGS1_k127_1286123_9 E1-E2 ATPase K01533,K12956 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 423.0
REGS1_k127_1399694_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.903e-217 687.0
REGS1_k127_1399694_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 510.0
REGS1_k127_1399694_10 FAD binding domain K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 290.0
REGS1_k127_1399694_11 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005402 286.0
REGS1_k127_1399694_12 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
REGS1_k127_1399694_13 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
REGS1_k127_1399694_14 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000001326 229.0
REGS1_k127_1399694_15 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000000000000000000000000000000393 204.0
REGS1_k127_1399694_16 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000001256 198.0
REGS1_k127_1399694_17 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000002423 188.0
REGS1_k127_1399694_18 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000005083 179.0
REGS1_k127_1399694_19 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000005938 170.0
REGS1_k127_1399694_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 490.0
REGS1_k127_1399694_20 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000004268 167.0
REGS1_k127_1399694_21 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000005002 158.0
REGS1_k127_1399694_22 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000001863 154.0
REGS1_k127_1399694_23 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.0000000000000000000000000000000000007985 146.0
REGS1_k127_1399694_24 PFAM AzlC family protein - - - 0.000000000000000000000000000000000006466 154.0
REGS1_k127_1399694_25 Acetyltransferase K03824 - - 0.00000000000000000000000000000118 131.0
REGS1_k127_1399694_26 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000185 119.0
REGS1_k127_1399694_27 - - - - 0.00000000000000006792 84.0
REGS1_k127_1399694_28 branched-chain amino acid - - - 0.000000000000001158 89.0
REGS1_k127_1399694_29 Desulfoferrodoxin K05919 - 1.15.1.2 0.000000000002604 76.0
REGS1_k127_1399694_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 426.0
REGS1_k127_1399694_30 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.000000002143 70.0
REGS1_k127_1399694_4 alcohol dehydrogenase K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
REGS1_k127_1399694_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 385.0
REGS1_k127_1399694_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 329.0
REGS1_k127_1399694_7 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 315.0
REGS1_k127_1399694_8 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 305.0
REGS1_k127_1399694_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
REGS1_k127_1419126_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 503.0
REGS1_k127_1419126_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 451.0
REGS1_k127_1419126_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003896 258.0
REGS1_k127_1419126_11 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001935 215.0
REGS1_k127_1419126_12 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000464 217.0
REGS1_k127_1419126_13 QueT transporter - - - 0.0000000000000000000000000000000000000000000000000004525 192.0
REGS1_k127_1419126_14 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000006962 191.0
REGS1_k127_1419126_15 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000002752 191.0
REGS1_k127_1419126_16 - - - - 0.00000000000000000000000000000000000000000001445 167.0
REGS1_k127_1419126_17 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000003697 141.0
REGS1_k127_1419126_18 membrane transporter protein K07090 - - 0.000000000000000000000000000103 126.0
REGS1_k127_1419126_19 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000001023 111.0
REGS1_k127_1419126_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 448.0
REGS1_k127_1419126_20 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000001151 94.0
REGS1_k127_1419126_21 EamA-like transporter family K03298 - - 0.000000000000000000615 100.0
REGS1_k127_1419126_22 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000004727 85.0
REGS1_k127_1419126_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 374.0
REGS1_k127_1419126_4 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 357.0
REGS1_k127_1419126_5 histidine kinase DNA gyrase B K07704 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 354.0
REGS1_k127_1419126_6 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 352.0
REGS1_k127_1419126_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000239 297.0
REGS1_k127_1419126_8 response regulator receiver K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
REGS1_k127_1419126_9 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001253 252.0
REGS1_k127_1574976_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 7.819e-227 709.0
REGS1_k127_1574976_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 328.0
REGS1_k127_1574976_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003211 247.0
REGS1_k127_1574976_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
REGS1_k127_1574976_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000009763 180.0
REGS1_k127_1574976_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000005285 174.0
REGS1_k127_1574976_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001649 163.0
REGS1_k127_1574976_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000007173 104.0
REGS1_k127_1574976_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000001642 58.0
REGS1_k127_1756727_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 378.0
REGS1_k127_1756727_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 301.0
REGS1_k127_1756727_2 PFAM extracellular solute-binding protein family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000002541 207.0
REGS1_k127_1756727_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000007831 142.0
REGS1_k127_1756727_4 Glycosyl transferases group 1 - - - 0.000000000000000009234 88.0
REGS1_k127_1854675_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.384e-294 922.0
REGS1_k127_1854675_1 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000004727 122.0
REGS1_k127_2011040_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 2.549e-231 747.0
REGS1_k127_2011040_1 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 546.0
REGS1_k127_2011040_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000005726 243.0
REGS1_k127_2011040_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000003008 228.0
REGS1_k127_2011040_12 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000004415 222.0
REGS1_k127_2011040_13 - - - - 0.00000000000000000000000000000000000000000000000000000000004674 214.0
REGS1_k127_2011040_14 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000002542 211.0
REGS1_k127_2011040_15 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000009348 212.0
REGS1_k127_2011040_16 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000004309 222.0
REGS1_k127_2011040_17 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000006723 213.0
REGS1_k127_2011040_18 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000002295 173.0
REGS1_k127_2011040_19 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000004993 178.0
REGS1_k127_2011040_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 532.0
REGS1_k127_2011040_20 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.0000000000000000000000000000000000000009207 156.0
REGS1_k127_2011040_21 Peptidyl-prolyl cis-trans isomerase K01802,K03774,K03775 - 5.2.1.8 0.000000000000000000000000000000000000006242 155.0
REGS1_k127_2011040_22 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000007628 162.0
REGS1_k127_2011040_23 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000595 153.0
REGS1_k127_2011040_24 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000002085 157.0
REGS1_k127_2011040_25 Major facilitator Superfamily K03291 - - 0.0000000000000000000000000000000004516 147.0
REGS1_k127_2011040_26 methyltransferase - - - 0.00000000000000000000000000000001778 145.0
REGS1_k127_2011040_27 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000485 130.0
REGS1_k127_2011040_28 Maf-like protein K06287 - - 0.000000000000000000000000006341 127.0
REGS1_k127_2011040_29 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000002334 116.0
REGS1_k127_2011040_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 375.0
REGS1_k127_2011040_30 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000001603 97.0
REGS1_k127_2011040_31 PspC domain K03973 - - 0.00000000000000000002558 96.0
REGS1_k127_2011040_32 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000008101 91.0
REGS1_k127_2011040_33 lyase activity - - - 0.000000000000003816 90.0
REGS1_k127_2011040_34 YtxH-like protein - - - 0.000000000428 68.0
REGS1_k127_2011040_35 - - - - 0.000000003743 64.0
REGS1_k127_2011040_36 PFAM PspC domain protein K03973 - - 0.000000004833 64.0
REGS1_k127_2011040_37 histidine kinase HAMP region domain protein - - - 0.00000001214 68.0
REGS1_k127_2011040_38 PFAM PRC-barrel domain - - - 0.00000001517 65.0
REGS1_k127_2011040_39 - - - - 0.00000001748 66.0
REGS1_k127_2011040_4 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 355.0
REGS1_k127_2011040_40 Transcriptional regulator - - - 0.0002481 49.0
REGS1_k127_2011040_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 312.0
REGS1_k127_2011040_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 278.0
REGS1_k127_2011040_7 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000232 254.0
REGS1_k127_2011040_8 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000005635 232.0
REGS1_k127_2011040_9 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000006899 228.0
REGS1_k127_2275190_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.475e-253 799.0
REGS1_k127_2275190_1 DNA ligase K01971 - 6.5.1.1 3.278e-227 736.0
REGS1_k127_2275190_10 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 498.0
REGS1_k127_2275190_11 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 504.0
REGS1_k127_2275190_12 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 391.0
REGS1_k127_2275190_13 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 352.0
REGS1_k127_2275190_14 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 339.0
REGS1_k127_2275190_15 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002304 253.0
REGS1_k127_2275190_16 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000003836 260.0
REGS1_k127_2275190_17 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
REGS1_k127_2275190_18 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000004862 236.0
REGS1_k127_2275190_19 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000002462 218.0
REGS1_k127_2275190_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.77e-205 656.0
REGS1_k127_2275190_20 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000001071 196.0
REGS1_k127_2275190_21 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000984 198.0
REGS1_k127_2275190_22 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000005049 183.0
REGS1_k127_2275190_23 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.00000000000000000000000000000000000000000007956 174.0
REGS1_k127_2275190_24 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000007671 168.0
REGS1_k127_2275190_25 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000002436 162.0
REGS1_k127_2275190_26 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000001093 151.0
REGS1_k127_2275190_27 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000009071 144.0
REGS1_k127_2275190_28 NIL domain - - - 0.0000000000000000000000000000002033 127.0
REGS1_k127_2275190_29 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000009598 129.0
REGS1_k127_2275190_3 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 607.0
REGS1_k127_2275190_30 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000006901 128.0
REGS1_k127_2275190_31 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000004648 108.0
REGS1_k127_2275190_32 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000009015 100.0
REGS1_k127_2275190_33 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000228 85.0
REGS1_k127_2275190_34 cell wall binding repeat - - - 0.000000000000002577 88.0
REGS1_k127_2275190_35 - - - - 0.000000000004168 74.0
REGS1_k127_2275190_36 PFAM ThiamineS - - - 0.000000000562 63.0
REGS1_k127_2275190_37 PFAM CAAX amino terminal protease family K07052 - - 0.000000001516 70.0
REGS1_k127_2275190_38 protein histidine kinase activity K07814,K11527 - 2.7.13.3 0.000000002054 70.0
REGS1_k127_2275190_39 COG0784 FOG CheY-like receiver - - - 0.000000004329 68.0
REGS1_k127_2275190_4 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 610.0
REGS1_k127_2275190_40 Integral membrane protein - - - 0.000000402 62.0
REGS1_k127_2275190_41 Nitrite and sulphite reductase 4Fe-4S domain K21816 - 1.8.98.3 0.0000004347 62.0
REGS1_k127_2275190_42 membrane K21471 - - 0.00001841 57.0
REGS1_k127_2275190_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 581.0
REGS1_k127_2275190_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 554.0
REGS1_k127_2275190_7 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 547.0
REGS1_k127_2275190_8 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 527.0
REGS1_k127_2275190_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 506.0
REGS1_k127_229850_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 3.165e-214 681.0
REGS1_k127_229850_1 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 4.56e-199 631.0
REGS1_k127_229850_10 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006331 282.0
REGS1_k127_229850_11 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000001164 272.0
REGS1_k127_229850_12 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000002458 242.0
REGS1_k127_229850_13 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000003507 230.0
REGS1_k127_229850_14 COGs COG0647 sugar phosphatase of the HAD superfamily K01101 - 3.1.3.41 0.000000000000000000000000000000000004522 149.0
REGS1_k127_229850_15 Glycosyltransferase family 87 - - - 0.0000000000000000000000004407 122.0
REGS1_k127_229850_16 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.000000000001969 79.0
REGS1_k127_229850_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 572.0
REGS1_k127_229850_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 425.0
REGS1_k127_229850_4 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 410.0
REGS1_k127_229850_5 ADP-glyceromanno-heptose 6-epimerase activity K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 411.0
REGS1_k127_229850_6 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
REGS1_k127_229850_7 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 382.0
REGS1_k127_229850_8 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 323.0
REGS1_k127_229850_9 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 304.0
REGS1_k127_2319785_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1090.0
REGS1_k127_2319785_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 358.0
REGS1_k127_2319785_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000001285 156.0
REGS1_k127_2319785_11 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000001638 139.0
REGS1_k127_2319785_12 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.00000000000000000000000000009705 123.0
REGS1_k127_2319785_13 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000001577 124.0
REGS1_k127_2319785_14 DivIVA domain protein K04074 - - 0.000000000000000000000000001223 123.0
REGS1_k127_2319785_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000221 112.0
REGS1_k127_2319785_16 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000671 94.0
REGS1_k127_2319785_17 DUF167 K09131 - - 0.000000000000001428 86.0
REGS1_k127_2319785_18 YGGT family K02221 - - 0.0001188 53.0
REGS1_k127_2319785_2 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 341.0
REGS1_k127_2319785_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 314.0
REGS1_k127_2319785_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000001416 249.0
REGS1_k127_2319785_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
REGS1_k127_2319785_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008115 243.0
REGS1_k127_2319785_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000000000000000000000000000000000000000000004091 208.0
REGS1_k127_2319785_8 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000001515 213.0
REGS1_k127_2319785_9 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000004509 196.0
REGS1_k127_2347512_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000001448 184.0
REGS1_k127_2347512_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000223 171.0
REGS1_k127_2347512_2 Glycosyl transferase - - - 0.00000000000000000000000000000000000001692 158.0
REGS1_k127_2347512_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000006827 158.0
REGS1_k127_2347512_4 Polysaccharide biosynthesis protein - - - 0.000000000000002153 91.0
REGS1_k127_2428268_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.605e-318 990.0
REGS1_k127_2428268_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 269.0
REGS1_k127_2428268_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000013 231.0
REGS1_k127_2428268_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000006436 157.0
REGS1_k127_2429833_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 430.0
REGS1_k127_2429833_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 360.0
REGS1_k127_2429833_2 extracellular solute-binding protein, family 1 K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003055 276.0
REGS1_k127_2429833_3 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006228 272.0
REGS1_k127_2429833_4 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 271.0
REGS1_k127_2429833_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000001061 222.0
REGS1_k127_2429833_6 ATPases associated with a variety of cellular activities K02068 - - 0.0000000000000000000000000000000000000000000009763 173.0
REGS1_k127_2429833_7 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000002179 119.0
REGS1_k127_2429833_8 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000001365 70.0
REGS1_k127_2429833_9 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00003703 55.0
REGS1_k127_2617447_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.454e-247 771.0
REGS1_k127_2617447_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.664e-225 704.0
REGS1_k127_2617447_10 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 346.0
REGS1_k127_2617447_11 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
REGS1_k127_2617447_12 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 324.0
REGS1_k127_2617447_13 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
REGS1_k127_2617447_14 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000064 298.0
REGS1_k127_2617447_15 PFAM Haemolysin-type calcium-binding repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004281 298.0
REGS1_k127_2617447_16 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000163 278.0
REGS1_k127_2617447_17 Bacterial transferase hexapeptide K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
REGS1_k127_2617447_18 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 256.0
REGS1_k127_2617447_19 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000001493 254.0
REGS1_k127_2617447_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 617.0
REGS1_k127_2617447_20 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000006931 248.0
REGS1_k127_2617447_21 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
REGS1_k127_2617447_22 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000000000006524 226.0
REGS1_k127_2617447_23 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000463 186.0
REGS1_k127_2617447_24 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000006395 177.0
REGS1_k127_2617447_25 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000004532 181.0
REGS1_k127_2617447_26 isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000009672 174.0
REGS1_k127_2617447_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000004011 151.0
REGS1_k127_2617447_28 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000001796 139.0
REGS1_k127_2617447_29 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000006606 107.0
REGS1_k127_2617447_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 599.0
REGS1_k127_2617447_30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000009746 104.0
REGS1_k127_2617447_31 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000001309 109.0
REGS1_k127_2617447_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000005309 83.0
REGS1_k127_2617447_33 cellulase activity - - - 0.0000000009134 73.0
REGS1_k127_2617447_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 582.0
REGS1_k127_2617447_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 507.0
REGS1_k127_2617447_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 490.0
REGS1_k127_2617447_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 465.0
REGS1_k127_2617447_8 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K13019 - 5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 435.0
REGS1_k127_2617447_9 Beta-eliminating lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 389.0
REGS1_k127_2719580_0 Required for chromosome condensation and partitioning K03529 - - 4.464e-284 914.0
REGS1_k127_2719580_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 516.0
REGS1_k127_2719580_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
REGS1_k127_2719580_11 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006002 274.0
REGS1_k127_2719580_12 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000006944 252.0
REGS1_k127_2719580_13 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000003528 184.0
REGS1_k127_2719580_14 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000001545 186.0
REGS1_k127_2719580_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000002819 181.0
REGS1_k127_2719580_16 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000009521 170.0
REGS1_k127_2719580_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000005537 162.0
REGS1_k127_2719580_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000004104 127.0
REGS1_k127_2719580_19 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000002611 110.0
REGS1_k127_2719580_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 515.0
REGS1_k127_2719580_20 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000511 100.0
REGS1_k127_2719580_21 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000001188 100.0
REGS1_k127_2719580_22 IMP dehydrogenase / GMP reductase domain - - - 0.000000000000000000305 89.0
REGS1_k127_2719580_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000008021 98.0
REGS1_k127_2719580_24 Belongs to the UPF0109 family K06960 - - 0.0000000000000004418 81.0
REGS1_k127_2719580_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 473.0
REGS1_k127_2719580_4 Mg chelatase-like protein K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 410.0
REGS1_k127_2719580_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 363.0
REGS1_k127_2719580_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 324.0
REGS1_k127_2719580_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 308.0
REGS1_k127_2719580_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
REGS1_k127_2719580_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009769 274.0
REGS1_k127_2884188_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1121.0
REGS1_k127_2884188_1 helix_turn_helix, Lux Regulon K03556 - - 4.358e-318 1010.0
REGS1_k127_2884188_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 500.0
REGS1_k127_2884188_11 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 466.0
REGS1_k127_2884188_12 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 465.0
REGS1_k127_2884188_13 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 463.0
REGS1_k127_2884188_14 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 427.0
REGS1_k127_2884188_15 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 394.0
REGS1_k127_2884188_16 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 389.0
REGS1_k127_2884188_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 355.0
REGS1_k127_2884188_18 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 355.0
REGS1_k127_2884188_19 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 297.0
REGS1_k127_2884188_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.845e-225 709.0
REGS1_k127_2884188_20 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 294.0
REGS1_k127_2884188_21 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 277.0
REGS1_k127_2884188_22 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 286.0
REGS1_k127_2884188_23 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006549 282.0
REGS1_k127_2884188_24 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005597 266.0
REGS1_k127_2884188_25 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000008432 265.0
REGS1_k127_2884188_26 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000018 258.0
REGS1_k127_2884188_27 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002181 256.0
REGS1_k127_2884188_28 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001055 249.0
REGS1_k127_2884188_29 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
REGS1_k127_2884188_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 8.963e-221 698.0
REGS1_k127_2884188_30 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
REGS1_k127_2884188_31 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000009982 217.0
REGS1_k127_2884188_32 Rifampin ADP-ribosyl transferase K19062 - - 0.000000000000000000000000000000000000000000000000000000000008471 209.0
REGS1_k127_2884188_33 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.00000000000000000000000000000000000000000000000000001072 198.0
REGS1_k127_2884188_34 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000001637 207.0
REGS1_k127_2884188_35 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000000000000006252 192.0
REGS1_k127_2884188_36 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000002384 186.0
REGS1_k127_2884188_37 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000382 160.0
REGS1_k127_2884188_38 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000004595 162.0
REGS1_k127_2884188_39 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000007284 154.0
REGS1_k127_2884188_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.914e-215 677.0
REGS1_k127_2884188_40 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000008598 142.0
REGS1_k127_2884188_41 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000008412 139.0
REGS1_k127_2884188_42 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000159 132.0
REGS1_k127_2884188_43 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.000000000000000000000000000005517 134.0
REGS1_k127_2884188_44 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000003024 126.0
REGS1_k127_2884188_45 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000285 105.0
REGS1_k127_2884188_46 Helix-turn-helix domain - - - 0.000000000000000000000003278 104.0
REGS1_k127_2884188_47 TrpR family protein YerC YecD - - - 0.00000000000000000000001256 104.0
REGS1_k127_2884188_48 - - - - 0.00000000000000000000002047 103.0
REGS1_k127_2884188_49 - - - - 0.00000000000000000000005294 108.0
REGS1_k127_2884188_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.053e-206 665.0
REGS1_k127_2884188_51 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000003302 101.0
REGS1_k127_2884188_52 hydrolase, family 25 - - - 0.00000000000003893 85.0
REGS1_k127_2884188_53 Zn-dependent protease with chaperone function K03799 - - 0.00001185 57.0
REGS1_k127_2884188_54 Alginate export - - - 0.0000352 53.0
REGS1_k127_2884188_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 583.0
REGS1_k127_2884188_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 543.0
REGS1_k127_2884188_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 524.0
REGS1_k127_2884188_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 543.0
REGS1_k127_3069665_0 Elongation factor SelB winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 574.0
REGS1_k127_3069665_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 459.0
REGS1_k127_3069665_10 DsrE/DsrF-like family - - - 0.0000000000000000000000002797 109.0
REGS1_k127_3069665_11 Protein of unknown function (DUF501) K09009 - - 0.00000000000000000003292 101.0
REGS1_k127_3069665_12 Methionine synthase B12-binding module cap domain protein - - - 0.000000002221 70.0
REGS1_k127_3069665_13 Tetratricopeptide TPR_2 repeat protein - - - 0.000000002291 70.0
REGS1_k127_3069665_14 cell cycle K05589,K12065,K13052 - - 0.00000003705 60.0
REGS1_k127_3069665_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 350.0
REGS1_k127_3069665_3 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006727 267.0
REGS1_k127_3069665_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000007861 233.0
REGS1_k127_3069665_5 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
REGS1_k127_3069665_6 protein histidine kinase activity K02484,K07640,K07643,K07645,K07649,K19609 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001381 204.0
REGS1_k127_3069665_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000006735 192.0
REGS1_k127_3069665_8 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000001557 139.0
REGS1_k127_3069665_9 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000256 122.0
REGS1_k127_3113099_0 Carbamoylphosphate synthase large subunit K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 508.0
REGS1_k127_3113099_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 385.0
REGS1_k127_3113099_10 integration host factor - - - 0.0000000000000000000000000007615 117.0
REGS1_k127_3113099_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.000000001351 63.0
REGS1_k127_3113099_12 Phospholipase_D-nuclease N-terminal - - - 0.000001311 56.0
REGS1_k127_3113099_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 385.0
REGS1_k127_3113099_3 abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 344.0
REGS1_k127_3113099_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002974 268.0
REGS1_k127_3113099_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000121 240.0
REGS1_k127_3113099_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000001336 242.0
REGS1_k127_3113099_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000348 202.0
REGS1_k127_3113099_8 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000009354 208.0
REGS1_k127_3113099_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000007892 184.0
REGS1_k127_3156275_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 394.0
REGS1_k127_3156275_1 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 342.0
REGS1_k127_3156275_10 Cytochrome b subunit of formate dehydrogenase-like protein - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000001043 118.0
REGS1_k127_3156275_11 Prokaryotic cytochrome b561 - - - 0.000000000000000000000009803 115.0
REGS1_k127_3156275_12 Zinc ion binding K11997,K12035 GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007610,GO:0007626,GO:0008150,GO:0008152,GO:0008270,GO:0008345,GO:0009653,GO:0009987,GO:0010927,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030537,GO:0031032,GO:0031674,GO:0032446,GO:0032501,GO:0032502,GO:0032989,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0046716,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048747,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0060249,GO:0061061,GO:0065007,GO:0065008,GO:0070647,GO:0070925,GO:0071704,GO:0071840,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564 2.3.2.27 0.0000000000000000000004164 107.0
REGS1_k127_3156275_13 denitrification pathway - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.000000000000000001307 100.0
REGS1_k127_3156275_14 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000008065 90.0
REGS1_k127_3156275_15 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000008395 89.0
REGS1_k127_3156275_16 - - - - 0.0001968 54.0
REGS1_k127_3156275_2 Cysteine desulfurase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 328.0
REGS1_k127_3156275_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000002223 250.0
REGS1_k127_3156275_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000001301 238.0
REGS1_k127_3156275_5 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000004706 214.0
REGS1_k127_3156275_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000001356 208.0
REGS1_k127_3156275_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000008672 190.0
REGS1_k127_3156275_8 TIGRFAM molybdenum cofactor synthesis - - - 0.00000000000000000000000000000000000000000000001744 175.0
REGS1_k127_3156275_9 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000000000000002472 145.0
REGS1_k127_3158708_0 DNA topoisomerase K03168 - 5.99.1.2 1.505e-263 833.0
REGS1_k127_3158708_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 609.0
REGS1_k127_3158708_10 Belongs to the LDH MDH superfamily K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 350.0
REGS1_k127_3158708_11 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 327.0
REGS1_k127_3158708_12 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 303.0
REGS1_k127_3158708_13 PSP1 C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 301.0
REGS1_k127_3158708_14 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 301.0
REGS1_k127_3158708_15 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002283 297.0
REGS1_k127_3158708_16 PDZ DHR GLGF domain protein K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002046 259.0
REGS1_k127_3158708_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004158 259.0
REGS1_k127_3158708_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
REGS1_k127_3158708_19 2-phosphoglycerate kinase K05715 - - 0.000000000000000000000000000000000000000000000000000000000000001911 235.0
REGS1_k127_3158708_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 580.0
REGS1_k127_3158708_20 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000001656 216.0
REGS1_k127_3158708_21 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000009059 209.0
REGS1_k127_3158708_22 Fumarase C-terminus K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000017 204.0
REGS1_k127_3158708_23 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000005914 209.0
REGS1_k127_3158708_24 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000006391 194.0
REGS1_k127_3158708_25 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.00000000000000000000000000000000000000000000001864 176.0
REGS1_k127_3158708_26 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000007299 172.0
REGS1_k127_3158708_27 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000001851 150.0
REGS1_k127_3158708_28 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000004648 131.0
REGS1_k127_3158708_29 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000008514 140.0
REGS1_k127_3158708_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 572.0
REGS1_k127_3158708_30 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000003452 111.0
REGS1_k127_3158708_31 Peptidase family M28 - - - 0.000000000000000000003061 106.0
REGS1_k127_3158708_32 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000004927 93.0
REGS1_k127_3158708_33 denitrification pathway - - - 0.00000000000000000005729 102.0
REGS1_k127_3158708_34 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000002333 67.0
REGS1_k127_3158708_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03116,K03117 - - 0.000000006318 62.0
REGS1_k127_3158708_36 STAS domain K20978 - - 0.00000001854 61.0
REGS1_k127_3158708_37 - - - - 0.0000004203 62.0
REGS1_k127_3158708_38 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000002145 61.0
REGS1_k127_3158708_39 cytochrome complex assembly K02200,K04018 - - 0.00000624 57.0
REGS1_k127_3158708_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 505.0
REGS1_k127_3158708_40 denitrification pathway K15876 - - 0.00001325 57.0
REGS1_k127_3158708_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 489.0
REGS1_k127_3158708_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 422.0
REGS1_k127_3158708_7 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 373.0
REGS1_k127_3158708_8 Transaldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 358.0
REGS1_k127_3158708_9 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 369.0
REGS1_k127_32413_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 9.427e-222 718.0
REGS1_k127_32413_1 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 568.0
REGS1_k127_32413_10 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001423 276.0
REGS1_k127_32413_11 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
REGS1_k127_32413_12 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007006 250.0
REGS1_k127_32413_13 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000001987 208.0
REGS1_k127_32413_14 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000001896 184.0
REGS1_k127_32413_15 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000001022 172.0
REGS1_k127_32413_16 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000327 182.0
REGS1_k127_32413_17 Stage II sporulation - - - 0.0000000000000000000000000000000000000000000002398 193.0
REGS1_k127_32413_18 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000354 175.0
REGS1_k127_32413_19 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000004124 173.0
REGS1_k127_32413_2 ABC transporter, ATP-binding protein K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 499.0
REGS1_k127_32413_20 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000002759 167.0
REGS1_k127_32413_21 Thioredoxin K03671 - - 0.000000000000000000000000000001375 123.0
REGS1_k127_32413_22 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000159 117.0
REGS1_k127_32413_23 Nitroreductase family - - - 0.00000000000000000000004419 106.0
REGS1_k127_32413_24 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000002672 102.0
REGS1_k127_32413_25 Domain of unknown function DUF302 - - - 0.0000000000000007998 85.0
REGS1_k127_32413_26 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000006255 89.0
REGS1_k127_32413_27 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.000000000001664 72.0
REGS1_k127_32413_28 Psort location Extracellular, score 9.55 - - - 0.000000000003688 78.0
REGS1_k127_32413_29 Heavy-metal-associated domain - - - 0.000000001858 61.0
REGS1_k127_32413_3 ABC transporter, ATP-binding protein K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 474.0
REGS1_k127_32413_30 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000001616 62.0
REGS1_k127_32413_31 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00003312 56.0
REGS1_k127_32413_32 4Fe-4S single cluster domain - - - 0.00006954 55.0
REGS1_k127_32413_4 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 442.0
REGS1_k127_32413_5 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 424.0
REGS1_k127_32413_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 315.0
REGS1_k127_32413_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 302.0
REGS1_k127_32413_8 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 293.0
REGS1_k127_32413_9 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006729 295.0
REGS1_k127_3337057_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.247e-273 857.0
REGS1_k127_3337057_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 398.0
REGS1_k127_3337057_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 334.0
REGS1_k127_3337057_3 RQC K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 331.0
REGS1_k127_3337057_4 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000002287 188.0
REGS1_k127_3337057_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000005319 140.0
REGS1_k127_3337057_6 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000002129 126.0
REGS1_k127_3337057_7 - - - - 0.00000000000000008786 94.0
REGS1_k127_3337057_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002278 76.0
REGS1_k127_3445338_0 DnaQ family exonuclease DinG family helicase K03722 - 3.6.4.12 1.368e-226 735.0
REGS1_k127_3445338_1 WYL domain K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000001813 91.0
REGS1_k127_3532136_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.411e-242 769.0
REGS1_k127_3532136_1 PFAM CoA-binding domain protein - - - 5.412e-209 674.0
REGS1_k127_3532136_10 transferase activity, transferring glycosyl groups K19002 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 0.000000000000000000000000000000000000000000000000000000000000000000000000000006799 289.0
REGS1_k127_3532136_11 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002195 264.0
REGS1_k127_3532136_12 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000001456 243.0
REGS1_k127_3532136_13 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001679 241.0
REGS1_k127_3532136_14 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000622 242.0
REGS1_k127_3532136_15 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000001083 240.0
REGS1_k127_3532136_16 ATPases associated with a variety of cellular activities K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000002061 222.0
REGS1_k127_3532136_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000006432 218.0
REGS1_k127_3532136_18 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000002764 200.0
REGS1_k127_3532136_19 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000002137 199.0
REGS1_k127_3532136_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 590.0
REGS1_k127_3532136_20 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000005455 163.0
REGS1_k127_3532136_21 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000003801 155.0
REGS1_k127_3532136_22 transmembrane transport K01992 - - 0.000000000000000000000000000000000001542 148.0
REGS1_k127_3532136_23 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000001296 141.0
REGS1_k127_3532136_24 - - - - 0.000000000000000000000000000003805 124.0
REGS1_k127_3532136_25 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000003573 124.0
REGS1_k127_3532136_26 Sortase family K07284,K22278 - 3.4.22.70,3.5.1.104 0.000000000000000000000000191 115.0
REGS1_k127_3532136_27 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000003699 113.0
REGS1_k127_3532136_28 PFAM plasmid stabilization system - - - 0.00000000000000000000009695 100.0
REGS1_k127_3532136_29 PFAM regulatory protein, MerR - - - 0.00000000000000000009254 99.0
REGS1_k127_3532136_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 522.0
REGS1_k127_3532136_30 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000009981 78.0
REGS1_k127_3532136_31 L,D-transpeptidase catalytic domain - - - 0.0000000004067 69.0
REGS1_k127_3532136_32 Type IV pilus biogenesis stability protein PilW - - - 0.000000005617 64.0
REGS1_k127_3532136_33 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.0000006475 62.0
REGS1_k127_3532136_34 - - - - 0.0001548 46.0
REGS1_k127_3532136_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 451.0
REGS1_k127_3532136_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 352.0
REGS1_k127_3532136_6 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 309.0
REGS1_k127_3532136_7 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 306.0
REGS1_k127_3532136_8 Permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
REGS1_k127_3532136_9 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002485 269.0
REGS1_k127_363584_0 Endoribonuclease that initiates mRNA decay K18682 - - 6.456e-211 666.0
REGS1_k127_363584_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 6.977e-203 645.0
REGS1_k127_363584_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000007374 254.0
REGS1_k127_363584_11 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
REGS1_k127_363584_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000202 188.0
REGS1_k127_363584_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000002238 171.0
REGS1_k127_363584_14 Helix-turn-helix domain - - - 0.0000000000000006645 88.0
REGS1_k127_363584_15 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000003161 77.0
REGS1_k127_363584_16 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002271 69.0
REGS1_k127_363584_2 FtsK SpoIIIE family K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 622.0
REGS1_k127_363584_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 509.0
REGS1_k127_363584_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 380.0
REGS1_k127_363584_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 374.0
REGS1_k127_363584_6 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 361.0
REGS1_k127_363584_7 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 363.0
REGS1_k127_363584_8 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 334.0
REGS1_k127_363584_9 competence damage-inducible protein CinA K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000001183 256.0
REGS1_k127_3660093_0 Multicopper oxidase - - - 0.0 1116.0
REGS1_k127_3660093_1 D-Lysine 5,6-aminomutase alpha subunit K17898 - 5.4.3.5 0.0 1045.0
REGS1_k127_3660093_10 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 456.0
REGS1_k127_3660093_100 Nucleotidyltransferase domain - - - 0.00000000006869 70.0
REGS1_k127_3660093_101 - - - - 0.0000000007621 71.0
REGS1_k127_3660093_102 Histidine kinase K07675 - 2.7.13.3 0.000000005142 67.0
REGS1_k127_3660093_103 pathogenesis K02417,K02519 - - 0.00000002444 65.0
REGS1_k127_3660093_104 Nucleotidyltransferase - - - 0.00000009441 61.0
REGS1_k127_3660093_105 Domain of unknown function (DUF4129) - - - 0.000000114 65.0
REGS1_k127_3660093_106 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000001308 59.0
REGS1_k127_3660093_107 PFAM HTH domain - - - 0.000002132 59.0
REGS1_k127_3660093_108 zinc-ribbon domain - - - 0.00002793 56.0
REGS1_k127_3660093_109 - - - - 0.0001347 52.0
REGS1_k127_3660093_11 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 430.0
REGS1_k127_3660093_110 - - - - 0.0004062 51.0
REGS1_k127_3660093_12 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 427.0
REGS1_k127_3660093_13 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 433.0
REGS1_k127_3660093_14 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 412.0
REGS1_k127_3660093_15 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 413.0
REGS1_k127_3660093_16 COGs COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 420.0
REGS1_k127_3660093_17 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 372.0
REGS1_k127_3660093_18 MutL protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 374.0
REGS1_k127_3660093_19 Dihydrodipicolinate reductase, N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 348.0
REGS1_k127_3660093_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.525e-235 743.0
REGS1_k127_3660093_20 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 342.0
REGS1_k127_3660093_21 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 333.0
REGS1_k127_3660093_22 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 327.0
REGS1_k127_3660093_23 glycine betaine transport K05845 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 320.0
REGS1_k127_3660093_24 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
REGS1_k127_3660093_25 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 313.0
REGS1_k127_3660093_26 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 303.0
REGS1_k127_3660093_27 phosphorylase K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 305.0
REGS1_k127_3660093_28 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 307.0
REGS1_k127_3660093_29 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 299.0
REGS1_k127_3660093_3 Pyridoxal-phosphate dependent enzyme K21400 - 2.3.1.263 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 599.0
REGS1_k127_3660093_30 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 314.0
REGS1_k127_3660093_31 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 296.0
REGS1_k127_3660093_32 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 291.0
REGS1_k127_3660093_33 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 292.0
REGS1_k127_3660093_34 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 286.0
REGS1_k127_3660093_35 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001114 290.0
REGS1_k127_3660093_36 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004988 287.0
REGS1_k127_3660093_37 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002424 286.0
REGS1_k127_3660093_38 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009504 299.0
REGS1_k127_3660093_39 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
REGS1_k127_3660093_4 conserved protein (DUF2075) K09384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 564.0
REGS1_k127_3660093_40 DNA repair exonuclease K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005937 291.0
REGS1_k127_3660093_41 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002245 283.0
REGS1_k127_3660093_42 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000008334 267.0
REGS1_k127_3660093_43 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 263.0
REGS1_k127_3660093_44 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002742 267.0
REGS1_k127_3660093_45 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000004639 256.0
REGS1_k127_3660093_46 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002161 260.0
REGS1_k127_3660093_47 histidine kinase DNA gyrase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001299 260.0
REGS1_k127_3660093_48 glycine betaine transport K05846 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - 0.00000000000000000000000000000000000000000000000000000000000000000000001359 249.0
REGS1_k127_3660093_49 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000008288 243.0
REGS1_k127_3660093_5 biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 550.0
REGS1_k127_3660093_50 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000002308 250.0
REGS1_k127_3660093_51 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
REGS1_k127_3660093_52 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000007517 250.0
REGS1_k127_3660093_53 EDD domain protein, DegV family - - - 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
REGS1_k127_3660093_54 COGs COG1174 ABC-type proline glycine betaine transport systems permease component K05846 - - 0.00000000000000000000000000000000000000000000000000000000001052 221.0
REGS1_k127_3660093_55 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000000000000000000000000004483 208.0
REGS1_k127_3660093_56 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000001549 197.0
REGS1_k127_3660093_57 NADH dehydrogenase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000006329 203.0
REGS1_k127_3660093_58 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000005153 199.0
REGS1_k127_3660093_59 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000001743 201.0
REGS1_k127_3660093_6 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 527.0
REGS1_k127_3660093_60 PFAM Quinolinate phosphoribosyl transferase K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000004617 207.0
REGS1_k127_3660093_61 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000007754 181.0
REGS1_k127_3660093_62 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000002475 173.0
REGS1_k127_3660093_63 AAA domain - - - 0.00000000000000000000000000000000000000005521 174.0
REGS1_k127_3660093_64 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000706 164.0
REGS1_k127_3660093_65 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000002129 154.0
REGS1_k127_3660093_66 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000002415 149.0
REGS1_k127_3660093_67 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000001161 149.0
REGS1_k127_3660093_68 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000001963 159.0
REGS1_k127_3660093_69 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000217 146.0
REGS1_k127_3660093_7 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 511.0
REGS1_k127_3660093_70 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000002029 143.0
REGS1_k127_3660093_71 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.00000000000000000000000000000002325 140.0
REGS1_k127_3660093_72 HNH endonuclease K07451 - - 0.0000000000000000000000000000001131 144.0
REGS1_k127_3660093_73 membrane K09790 - - 0.0000000000000000000000000000003538 128.0
REGS1_k127_3660093_74 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000009947 129.0
REGS1_k127_3660093_75 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000021 132.0
REGS1_k127_3660093_76 D-ornithine 4,5-aminomutase alpha-subunit K17899 - 5.4.3.5 0.000000000000000000000000004225 114.0
REGS1_k127_3660093_77 RDD family - - - 0.00000000000000000000000000662 120.0
REGS1_k127_3660093_78 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000002715 122.0
REGS1_k127_3660093_79 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000161 117.0
REGS1_k127_3660093_8 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 496.0
REGS1_k127_3660093_80 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000005362 115.0
REGS1_k127_3660093_81 BioY family K03523 - - 0.0000000000000000000000006731 111.0
REGS1_k127_3660093_82 peptidase S1 and S6, chymotrypsin Hap K01337 - 3.4.21.50 0.000000000000000000000006485 118.0
REGS1_k127_3660093_83 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.0000000000000000000001036 101.0
REGS1_k127_3660093_84 amino acid activation for nonribosomal peptide biosynthetic process K02406,K19693 - - 0.000000000000000000004532 111.0
REGS1_k127_3660093_85 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000006134 104.0
REGS1_k127_3660093_86 SNARE associated Golgi protein K03975 - - 0.000000000000000000007293 108.0
REGS1_k127_3660093_87 belongs to the nudix hydrolase family - - - 0.00000000000000000001473 100.0
REGS1_k127_3660093_88 intracellular protein transport K05989 - 3.2.1.40 0.00000000000000000002291 106.0
REGS1_k127_3660093_89 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000008953 96.0
REGS1_k127_3660093_9 PFAM Alcohol dehydrogenase GroES-like K00004,K00008,K00060 - 1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 502.0
REGS1_k127_3660093_90 PFAM glutaredoxin K06191 - - 0.0000000000000000009365 91.0
REGS1_k127_3660093_91 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000001643 95.0
REGS1_k127_3660093_92 phosphorelay signal transduction system - - - 0.000000000000000003376 92.0
REGS1_k127_3660093_93 Serine aminopeptidase, S33 - - - 0.00000000000000001029 95.0
REGS1_k127_3660093_94 - - - - 0.000000000000001899 88.0
REGS1_k127_3660093_95 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000003199 79.0
REGS1_k127_3660093_96 Transcriptional regulator - - - 0.000000000001005 79.0
REGS1_k127_3660093_97 PilT protein domain protein - - - 0.000000000004315 72.0
REGS1_k127_3660093_98 transcriptional regulator - - - 0.00000000002795 76.0
REGS1_k127_3660093_99 Prepilin-type cleavage methylation N-terminal domain protein K02650 - - 0.00000000003291 70.0
REGS1_k127_3736443_0 PFAM Band 7 protein - - - 1.032e-194 615.0
REGS1_k127_3736443_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 543.0
REGS1_k127_3736443_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 489.0
REGS1_k127_3736443_3 cheY-homologous receiver domain - - - 0.0000000000000000000000004361 110.0
REGS1_k127_3736443_4 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000006278 95.0
REGS1_k127_3774104_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 399.0
REGS1_k127_3774104_1 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
REGS1_k127_3774104_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 333.0
REGS1_k127_3774104_3 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001736 268.0
REGS1_k127_3774104_4 copper ion binding K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000002432 183.0
REGS1_k127_3783555_0 Conserved region in glutamate synthase - - - 2.037e-250 784.0
REGS1_k127_3783555_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 615.0
REGS1_k127_3783555_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 327.0
REGS1_k127_3783555_3 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002059 280.0
REGS1_k127_3783555_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009458 272.0
REGS1_k127_3783555_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000009395 239.0
REGS1_k127_3783555_6 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000002298 64.0
REGS1_k127_3783555_7 PFAM TOBE domain K02019 - - 0.000002317 53.0
REGS1_k127_3975780_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 424.0
REGS1_k127_3975780_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 404.0
REGS1_k127_3975780_10 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0001616 55.0
REGS1_k127_3975780_2 Bacterial sugar transferase K19428 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
REGS1_k127_3975780_3 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000009079 208.0
REGS1_k127_3975780_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000156 156.0
REGS1_k127_3975780_5 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000315 151.0
REGS1_k127_3975780_6 peptidase inhibitor activity K04771 - 3.4.21.107 0.00000000000000194 91.0
REGS1_k127_3975780_8 ResB protein required for cytochrome c biosynthesis K07399 - - 0.0000001281 64.0
REGS1_k127_3975780_9 Polysaccharide deacetylase - - - 0.000004376 52.0
REGS1_k127_4108772_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.41e-305 955.0
REGS1_k127_4108772_1 HypF finger K04656 - - 2.207e-229 737.0
REGS1_k127_4108772_10 hydrogenase assembly chaperone HypC HupF K04653 - - 0.000000000000000000797 90.0
REGS1_k127_4108772_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000005563 66.0
REGS1_k127_4108772_12 Tetratricopeptide repeat - - - 0.00004272 55.0
REGS1_k127_4108772_2 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 462.0
REGS1_k127_4108772_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 297.0
REGS1_k127_4108772_4 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001302 279.0
REGS1_k127_4108772_5 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000001325 204.0
REGS1_k127_4108772_6 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000005759 179.0
REGS1_k127_4108772_7 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000004657 143.0
REGS1_k127_4108772_8 Cobalt ABC transporter K02008 - - 0.000000000000000000000000001812 129.0
REGS1_k127_4108772_9 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000001373 102.0
REGS1_k127_4159240_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 453.0
REGS1_k127_4159240_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 392.0
REGS1_k127_4159240_10 hydrolase K01048 - 3.1.1.5 0.00000003341 56.0
REGS1_k127_4159240_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 323.0
REGS1_k127_4159240_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 292.0
REGS1_k127_4159240_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007905 284.0
REGS1_k127_4159240_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005836 280.0
REGS1_k127_4159240_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000007252 228.0
REGS1_k127_4159240_7 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.0000000000000000000000000000000007108 136.0
REGS1_k127_4159240_8 Rubrerythrin K19824 - - 0.00000000000000000000000000005859 127.0
REGS1_k127_4159240_9 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000019 103.0
REGS1_k127_4244883_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 448.0
REGS1_k127_4244883_1 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 269.0
REGS1_k127_4244883_2 SMART phosphoesterase PHP domain protein K04477 - - 0.000000000000000000000000000000000000000000000000000000003423 209.0
REGS1_k127_4244883_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000003692 158.0
REGS1_k127_4244883_4 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000251 168.0
REGS1_k127_4244883_5 PIN domain - - - 0.000000000000000000000002829 108.0
REGS1_k127_4289312_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1219.0
REGS1_k127_4289312_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1137.0
REGS1_k127_4289312_10 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 356.0
REGS1_k127_4289312_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 352.0
REGS1_k127_4289312_12 RNA modification enzyme, MiaB family K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 309.0
REGS1_k127_4289312_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004961 280.0
REGS1_k127_4289312_14 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001497 263.0
REGS1_k127_4289312_15 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002398 268.0
REGS1_k127_4289312_16 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004511 252.0
REGS1_k127_4289312_17 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000001676 236.0
REGS1_k127_4289312_18 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000008044 236.0
REGS1_k127_4289312_19 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000001012 207.0
REGS1_k127_4289312_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.541e-297 921.0
REGS1_k127_4289312_20 Transporter associated domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000002267 207.0
REGS1_k127_4289312_21 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000007607 217.0
REGS1_k127_4289312_22 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000002228 198.0
REGS1_k127_4289312_23 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000000000000000000000000000000000000000004922 191.0
REGS1_k127_4289312_24 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002378 188.0
REGS1_k127_4289312_25 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000009622 182.0
REGS1_k127_4289312_26 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000009762 171.0
REGS1_k127_4289312_27 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000001696 154.0
REGS1_k127_4289312_28 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000001339 161.0
REGS1_k127_4289312_29 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000002134 152.0
REGS1_k127_4289312_3 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 9.441e-215 688.0
REGS1_k127_4289312_30 SLBB domain K02237 - - 0.0000000000000000000000000000000007355 139.0
REGS1_k127_4289312_31 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000001213 128.0
REGS1_k127_4289312_32 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000002529 128.0
REGS1_k127_4289312_33 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000006746 124.0
REGS1_k127_4289312_34 heat shock protein binding - - - 0.0000000000000000000000001806 119.0
REGS1_k127_4289312_35 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000003706 105.0
REGS1_k127_4289312_36 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000008516 103.0
REGS1_k127_4289312_37 Transcriptional regulatory protein, C terminal - - - 0.0000000000000001034 84.0
REGS1_k127_4289312_38 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000002208 87.0
REGS1_k127_4289312_39 PIN domain - - - 0.0000000000001128 76.0
REGS1_k127_4289312_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 601.0
REGS1_k127_4289312_40 Antitoxin Phd_YefM, type II toxin-antitoxin system K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000001656 63.0
REGS1_k127_4289312_41 Protein of unknown function (DUF3616) - - - 0.000000002413 72.0
REGS1_k127_4289312_42 Transcriptional regulator - - - 0.000000003924 65.0
REGS1_k127_4289312_43 - - - - 0.00000003783 68.0
REGS1_k127_4289312_44 Domain of unknown function (DUF4339) - - - 0.0000006078 62.0
REGS1_k127_4289312_45 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000002348 62.0
REGS1_k127_4289312_46 PFAM SpoVT AbrB - - - 0.000004244 53.0
REGS1_k127_4289312_47 Exopolysaccharide production protein K16568 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000008604 57.0
REGS1_k127_4289312_48 PIN domain - - - 0.00001217 53.0
REGS1_k127_4289312_49 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0002525 55.0
REGS1_k127_4289312_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 516.0
REGS1_k127_4289312_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 490.0
REGS1_k127_4289312_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 480.0
REGS1_k127_4289312_8 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 413.0
REGS1_k127_4289312_9 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 400.0
REGS1_k127_4348270_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 474.0
REGS1_k127_4348270_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
REGS1_k127_4348270_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000001332 194.0
REGS1_k127_4348270_3 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000192 127.0
REGS1_k127_4348270_4 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000005648 94.0
REGS1_k127_4463217_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 2.789e-245 785.0
REGS1_k127_4463217_1 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 7.725e-245 776.0
REGS1_k127_4463217_10 Heavy metal transport detoxification protein - - - 0.00000000000000000000000000000000000000000000000002612 196.0
REGS1_k127_4463217_11 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000436 179.0
REGS1_k127_4463217_12 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.000000000000000004994 91.0
REGS1_k127_4463217_13 Cupredoxin-like domain - - - 0.0000000000002407 79.0
REGS1_k127_4463217_14 Nacht domain - - - 0.000000001355 67.0
REGS1_k127_4463217_15 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.00000005678 64.0
REGS1_k127_4463217_16 membrane protein (DUF2078) K08982 - - 0.0000001295 57.0
REGS1_k127_4463217_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 560.0
REGS1_k127_4463217_3 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 413.0
REGS1_k127_4463217_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 415.0
REGS1_k127_4463217_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 404.0
REGS1_k127_4463217_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
REGS1_k127_4463217_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004592 282.0
REGS1_k127_4463217_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004268 249.0
REGS1_k127_4463217_9 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000003709 222.0
REGS1_k127_4693393_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 484.0
REGS1_k127_4693393_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
REGS1_k127_4693393_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000008568 213.0
REGS1_k127_4693393_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000003741 205.0
REGS1_k127_4693393_12 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000008324 199.0
REGS1_k127_4693393_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000001567 197.0
REGS1_k127_4693393_14 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000001598 177.0
REGS1_k127_4693393_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000007546 169.0
REGS1_k127_4693393_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000003731 154.0
REGS1_k127_4693393_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000001148 153.0
REGS1_k127_4693393_18 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000001505 144.0
REGS1_k127_4693393_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000009293 141.0
REGS1_k127_4693393_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
REGS1_k127_4693393_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000116 116.0
REGS1_k127_4693393_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000341 109.0
REGS1_k127_4693393_22 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000007427 81.0
REGS1_k127_4693393_23 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002747 78.0
REGS1_k127_4693393_24 Methionine aminopeptidase K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.0000000000001436 76.0
REGS1_k127_4693393_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004856 276.0
REGS1_k127_4693393_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005427 272.0
REGS1_k127_4693393_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001317 262.0
REGS1_k127_4693393_6 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004248 259.0
REGS1_k127_4693393_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000007781 244.0
REGS1_k127_4693393_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001328 233.0
REGS1_k127_4693393_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002794 218.0
REGS1_k127_4742104_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.122e-232 735.0
REGS1_k127_4742104_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 5.403e-222 698.0
REGS1_k127_4742104_10 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000001646 223.0
REGS1_k127_4742104_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000838 187.0
REGS1_k127_4742104_12 diacylglycerol kinase, catalytic - - - 0.0000000000000000000000000000000000000000000003409 180.0
REGS1_k127_4742104_13 NLP P60 protein K21471 - - 0.000000000000000000000000000000000000000000215 174.0
REGS1_k127_4742104_14 General secretory system II protein E domain protein - - - 0.00000000000000000000000000000000000000001498 170.0
REGS1_k127_4742104_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000007775 133.0
REGS1_k127_4742104_16 ATP synthase subunit C K02124 - - 0.00000000000000000000000000008245 126.0
REGS1_k127_4742104_17 - - - - 0.00000000000000000000001316 114.0
REGS1_k127_4742104_18 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000002645 111.0
REGS1_k127_4742104_19 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000001641 83.0
REGS1_k127_4742104_2 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 514.0
REGS1_k127_4742104_20 (Hpt) domain - - - 0.0000000000000004392 85.0
REGS1_k127_4742104_21 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000006692 81.0
REGS1_k127_4742104_22 ATP synthase, subunit F K02122 - - 0.0000000006546 70.0
REGS1_k127_4742104_23 - - - - 0.00000000252 61.0
REGS1_k127_4742104_25 phosphatase - - - 0.000008629 56.0
REGS1_k127_4742104_3 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 477.0
REGS1_k127_4742104_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 333.0
REGS1_k127_4742104_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 322.0
REGS1_k127_4742104_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 297.0
REGS1_k127_4742104_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008442 268.0
REGS1_k127_4742104_8 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001047 261.0
REGS1_k127_4742104_9 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000001363 260.0
REGS1_k127_4799190_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 2.213e-208 662.0
REGS1_k127_4799190_1 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 344.0
REGS1_k127_4799190_10 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000009568 124.0
REGS1_k127_4799190_11 Polysaccharide biosynthesis protein - - - 0.000009171 58.0
REGS1_k127_4799190_12 -O-antigen K18814 - - 0.00001001 59.0
REGS1_k127_4799190_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002912 303.0
REGS1_k127_4799190_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004762 258.0
REGS1_k127_4799190_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001553 221.0
REGS1_k127_4799190_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - - 0.000000000000000000000000000000000000000003616 175.0
REGS1_k127_4799190_6 LICD family K07271 - - 0.00000000000000000000000000000000000000006847 175.0
REGS1_k127_4799190_7 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000003173 162.0
REGS1_k127_4799190_8 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001249 160.0
REGS1_k127_4799190_9 Glycosyltransferase like family 2 K13002 - - 0.0000000000000000000000000002633 132.0
REGS1_k127_4827412_0 PFAM AMP-dependent synthetase and ligase K00666 - - 6.953e-299 923.0
REGS1_k127_4827412_1 Tocopherol cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003705 282.0
REGS1_k127_4827412_2 Cupin domain K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
REGS1_k127_4827412_3 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000005856 167.0
REGS1_k127_4827412_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000005335 123.0
REGS1_k127_4827412_5 - - - - 0.0000000000000002947 85.0
REGS1_k127_4827412_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000009321 76.0
REGS1_k127_4827412_7 Protein of unknown function (DUF2510) - - - 0.0000001733 59.0
REGS1_k127_4886988_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1103.0
REGS1_k127_4886988_1 Heat shock 70 kDa protein K04043 - - 8.672e-298 925.0
REGS1_k127_4886988_10 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 307.0
REGS1_k127_4886988_11 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 302.0
REGS1_k127_4886988_12 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001283 295.0
REGS1_k127_4886988_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001497 247.0
REGS1_k127_4886988_14 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003215 250.0
REGS1_k127_4886988_15 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000008538 240.0
REGS1_k127_4886988_16 Protein of unknown function (DUF4004) - - - 0.00000000000000000000000000000000000000000000000000004268 194.0
REGS1_k127_4886988_17 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000000000000000000000000000839 194.0
REGS1_k127_4886988_18 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000000001441 197.0
REGS1_k127_4886988_19 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000008668 166.0
REGS1_k127_4886988_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.533e-205 647.0
REGS1_k127_4886988_20 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000003497 160.0
REGS1_k127_4886988_21 heat shock protein binding - - - 0.000000000000000000000000000000000009727 152.0
REGS1_k127_4886988_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000001609 139.0
REGS1_k127_4886988_23 MerR HTH family regulatory protein K13640 - - 0.00000000000000000000000000006936 123.0
REGS1_k127_4886988_24 Sortase family - - - 0.0000000000000000000000000003405 123.0
REGS1_k127_4886988_25 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000000000000000594 95.0
REGS1_k127_4886988_26 4Fe-4S binding domain - - - 0.00000000000000000001185 93.0
REGS1_k127_4886988_27 Cupredoxin-like domain - - - 0.000000000000000562 84.0
REGS1_k127_4886988_28 - - - - 0.00000000002815 72.0
REGS1_k127_4886988_29 RNA-binding protein containing a PIN domain K06962 - - 0.0000009586 58.0
REGS1_k127_4886988_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 512.0
REGS1_k127_4886988_30 bacterioferritin comigratory protein K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000003286 52.0
REGS1_k127_4886988_31 Protein of unknown function (DUF1003) - - - 0.00005936 47.0
REGS1_k127_4886988_4 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 391.0
REGS1_k127_4886988_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 376.0
REGS1_k127_4886988_6 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 350.0
REGS1_k127_4886988_7 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 353.0
REGS1_k127_4886988_8 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 332.0
REGS1_k127_4886988_9 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 311.0
REGS1_k127_4993833_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 1.536e-268 839.0
REGS1_k127_4993833_1 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 2.777e-225 737.0
REGS1_k127_4993833_10 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 561.0
REGS1_k127_4993833_100 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000005299 79.0
REGS1_k127_4993833_101 - - - - 0.0000000000008847 78.0
REGS1_k127_4993833_102 Regulatory protein, FmdB family - - - 0.000000000008516 78.0
REGS1_k127_4993833_103 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000001998 71.0
REGS1_k127_4993833_104 NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000006939 69.0
REGS1_k127_4993833_105 - - - - 0.000000002064 63.0
REGS1_k127_4993833_106 - - - - 0.00000007626 59.0
REGS1_k127_4993833_107 Protein of unknown function (DUF2510) - - - 0.0000008941 59.0
REGS1_k127_4993833_108 Mitochondrial biogenesis AIM24 - - - 0.000001031 59.0
REGS1_k127_4993833_109 type 3a cellulose-binding domain protein K01179,K05988 - 3.2.1.11,3.2.1.4 0.00000236 59.0
REGS1_k127_4993833_11 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 561.0
REGS1_k127_4993833_110 Domain of unknown function (DUF1858) - - - 0.000003359 57.0
REGS1_k127_4993833_112 Phosphate-starvation-inducible E - - - 0.00002368 54.0
REGS1_k127_4993833_12 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 512.0
REGS1_k127_4993833_13 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 500.0
REGS1_k127_4993833_14 DAK2 domain fusion protein YloV K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 477.0
REGS1_k127_4993833_15 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 466.0
REGS1_k127_4993833_16 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
REGS1_k127_4993833_17 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 434.0
REGS1_k127_4993833_18 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 430.0
REGS1_k127_4993833_19 Kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 419.0
REGS1_k127_4993833_2 ABC transporter K06158 - - 1.146e-214 687.0
REGS1_k127_4993833_20 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 402.0
REGS1_k127_4993833_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 407.0
REGS1_k127_4993833_22 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 405.0
REGS1_k127_4993833_23 PFAM 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 387.0
REGS1_k127_4993833_24 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 388.0
REGS1_k127_4993833_25 fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 371.0
REGS1_k127_4993833_26 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 375.0
REGS1_k127_4993833_27 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 367.0
REGS1_k127_4993833_28 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 378.0
REGS1_k127_4993833_29 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 356.0
REGS1_k127_4993833_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 1.266e-211 704.0
REGS1_k127_4993833_30 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 339.0
REGS1_k127_4993833_31 2-nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 328.0
REGS1_k127_4993833_32 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 342.0
REGS1_k127_4993833_33 FeS-containing Cyanobacterial-specific oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 331.0
REGS1_k127_4993833_34 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 342.0
REGS1_k127_4993833_35 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 323.0
REGS1_k127_4993833_36 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 311.0
REGS1_k127_4993833_37 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 298.0
REGS1_k127_4993833_38 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 299.0
REGS1_k127_4993833_39 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003573 291.0
REGS1_k127_4993833_4 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 6.368e-196 635.0
REGS1_k127_4993833_40 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003762 274.0
REGS1_k127_4993833_41 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
REGS1_k127_4993833_42 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002187 269.0
REGS1_k127_4993833_43 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000006402 280.0
REGS1_k127_4993833_44 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
REGS1_k127_4993833_45 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000008433 262.0
REGS1_k127_4993833_46 DNA polymerase III, epsilon subunit K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000001642 265.0
REGS1_k127_4993833_47 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000005542 265.0
REGS1_k127_4993833_48 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000006841 264.0
REGS1_k127_4993833_49 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000001035 250.0
REGS1_k127_4993833_5 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 634.0
REGS1_k127_4993833_50 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000004535 238.0
REGS1_k127_4993833_51 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000002066 232.0
REGS1_k127_4993833_52 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000002876 249.0
REGS1_k127_4993833_53 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000005285 243.0
REGS1_k127_4993833_54 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000001462 228.0
REGS1_k127_4993833_55 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000005576 207.0
REGS1_k127_4993833_56 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000002143 198.0
REGS1_k127_4993833_57 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000001136 209.0
REGS1_k127_4993833_58 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000003044 208.0
REGS1_k127_4993833_59 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000493 197.0
REGS1_k127_4993833_6 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 619.0
REGS1_k127_4993833_60 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000007325 201.0
REGS1_k127_4993833_61 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000007441 202.0
REGS1_k127_4993833_62 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000002834 195.0
REGS1_k127_4993833_63 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000005363 202.0
REGS1_k127_4993833_64 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001803 188.0
REGS1_k127_4993833_65 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000007729 190.0
REGS1_k127_4993833_66 Belongs to the peptidase S8 family K14645,K14743 - - 0.000000000000000000000000000000000000000000000004966 195.0
REGS1_k127_4993833_67 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000008729 177.0
REGS1_k127_4993833_68 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000004192 177.0
REGS1_k127_4993833_69 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000356 165.0
REGS1_k127_4993833_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 596.0
REGS1_k127_4993833_70 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000001281 165.0
REGS1_k127_4993833_71 PIN domain - - - 0.0000000000000000000000000000000000000000001325 162.0
REGS1_k127_4993833_72 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000001115 171.0
REGS1_k127_4993833_73 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.000000000000000000000000000000000000003603 154.0
REGS1_k127_4993833_74 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000000008556 146.0
REGS1_k127_4993833_75 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000003504 152.0
REGS1_k127_4993833_76 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000002037 147.0
REGS1_k127_4993833_77 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000001504 138.0
REGS1_k127_4993833_78 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000229 143.0
REGS1_k127_4993833_79 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000003084 132.0
REGS1_k127_4993833_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 572.0
REGS1_k127_4993833_80 thiamine transport K16789 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000008785 139.0
REGS1_k127_4993833_81 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000002148 134.0
REGS1_k127_4993833_82 - - - - 0.00000000000000000000000000000001957 130.0
REGS1_k127_4993833_83 heme binding K21471,K21472 - - 0.0000000000000000000000000000002228 139.0
REGS1_k127_4993833_84 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000001552 135.0
REGS1_k127_4993833_85 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000007538 124.0
REGS1_k127_4993833_86 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000001518 123.0
REGS1_k127_4993833_87 Thermostable dipeptidase. Metallo peptidase. MEROPS family M19 K01273 - 3.4.13.19 0.0000000000000000000000000005561 124.0
REGS1_k127_4993833_88 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000818 125.0
REGS1_k127_4993833_89 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000003032 122.0
REGS1_k127_4993833_9 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 577.0
REGS1_k127_4993833_90 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000001427 121.0
REGS1_k127_4993833_91 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000002353 109.0
REGS1_k127_4993833_92 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000008866 103.0
REGS1_k127_4993833_93 SpoVT / AbrB like domain - - - 0.00000000000000000000009435 99.0
REGS1_k127_4993833_94 zinc ribbon domain K07164 - - 0.0000000000000000002362 96.0
REGS1_k127_4993833_95 Ribonuclease K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000915 100.0
REGS1_k127_4993833_96 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.0000000000000000312 95.0
REGS1_k127_4993833_97 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000002524 83.0
REGS1_k127_4993833_98 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000001516 83.0
REGS1_k127_4993833_99 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000004146 77.0
REGS1_k127_5022622_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.584e-249 779.0
REGS1_k127_5022622_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.854e-228 722.0
REGS1_k127_5022622_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 357.0
REGS1_k127_5022622_11 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 346.0
REGS1_k127_5022622_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 355.0
REGS1_k127_5022622_13 integral membrane protein MviN K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 345.0
REGS1_k127_5022622_14 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 340.0
REGS1_k127_5022622_15 Peptidase dimerisation domain K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 341.0
REGS1_k127_5022622_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 307.0
REGS1_k127_5022622_17 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 293.0
REGS1_k127_5022622_18 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 293.0
REGS1_k127_5022622_19 Protein of unknown function (DUF3866) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005254 287.0
REGS1_k127_5022622_2 ABC transporter, ATP-binding protein K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 577.0
REGS1_k127_5022622_20 Cell cycle protein K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 287.0
REGS1_k127_5022622_21 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005044 279.0
REGS1_k127_5022622_22 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000001618 254.0
REGS1_k127_5022622_23 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001112 238.0
REGS1_k127_5022622_24 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000003386 217.0
REGS1_k127_5022622_25 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000009783 177.0
REGS1_k127_5022622_26 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000938 138.0
REGS1_k127_5022622_27 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.000000000000000000000000000000006092 140.0
REGS1_k127_5022622_28 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000966 130.0
REGS1_k127_5022622_29 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000005291 111.0
REGS1_k127_5022622_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 520.0
REGS1_k127_5022622_30 Copper transport outer membrane protein, MctB - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796 - 0.00000000799 68.0
REGS1_k127_5022622_4 Belongs to the MurCDEF family. MurE subfamily K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 445.0
REGS1_k127_5022622_5 Thiamine pyrophosphokinase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 428.0
REGS1_k127_5022622_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 404.0
REGS1_k127_5022622_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 383.0
REGS1_k127_5022622_8 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 397.0
REGS1_k127_5022622_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 371.0
REGS1_k127_5082651_0 GTP-binding protein TypA K06207 - - 3.737e-290 902.0
REGS1_k127_5082651_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.758e-287 914.0
REGS1_k127_5082651_10 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 448.0
REGS1_k127_5082651_11 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 414.0
REGS1_k127_5082651_12 alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 412.0
REGS1_k127_5082651_13 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 414.0
REGS1_k127_5082651_14 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 375.0
REGS1_k127_5082651_15 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 326.0
REGS1_k127_5082651_16 Arginase family K01479,K01480 - 3.5.3.11,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 338.0
REGS1_k127_5082651_17 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 337.0
REGS1_k127_5082651_18 TipAS antibiotic-recognition domain K21744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 301.0
REGS1_k127_5082651_19 TIGRFAM phosphonopyruvate decarboxylase-related protein K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 306.0
REGS1_k127_5082651_2 ABC transporter, transmembrane region K06147 - - 6.267e-256 829.0
REGS1_k127_5082651_20 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
REGS1_k127_5082651_21 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 275.0
REGS1_k127_5082651_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000518 286.0
REGS1_k127_5082651_23 Methyltransferase K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000001651 268.0
REGS1_k127_5082651_24 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000101 286.0
REGS1_k127_5082651_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007691 259.0
REGS1_k127_5082651_26 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004283 251.0
REGS1_k127_5082651_27 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005887 256.0
REGS1_k127_5082651_28 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000003964 250.0
REGS1_k127_5082651_29 Voltage-dependent anion channel K11041 - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 243.0
REGS1_k127_5082651_3 ABC transporter, transmembrane region K06147 - - 1.208e-246 781.0
REGS1_k127_5082651_30 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004877 250.0
REGS1_k127_5082651_31 Transcriptional regulatory protein, C terminal K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000000000000007789 224.0
REGS1_k127_5082651_32 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
REGS1_k127_5082651_33 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01563,K04075,K11991 - 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000001015 213.0
REGS1_k127_5082651_34 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000002778 207.0
REGS1_k127_5082651_35 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000006524 206.0
REGS1_k127_5082651_36 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000007607 201.0
REGS1_k127_5082651_37 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000002764 189.0
REGS1_k127_5082651_38 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000007431 188.0
REGS1_k127_5082651_39 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000002536 179.0
REGS1_k127_5082651_4 Aromatic amino acid lyase K01745 - 4.3.1.3 2.325e-215 679.0
REGS1_k127_5082651_40 Belongs to the MsrB Met sulfoxide reductase family - - - 0.00000000000000000000000000000000000000000000003309 173.0
REGS1_k127_5082651_41 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000003637 190.0
REGS1_k127_5082651_42 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000003338 188.0
REGS1_k127_5082651_43 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000007165 181.0
REGS1_k127_5082651_44 - - - - 0.00000000000000000000000000000000000000000001387 172.0
REGS1_k127_5082651_45 membrane - - - 0.000000000000000000000000000000000000002734 154.0
REGS1_k127_5082651_46 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000001756 154.0
REGS1_k127_5082651_47 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000004101 156.0
REGS1_k127_5082651_48 heat shock protein binding - - - 0.0000000000000000000000000000000000004614 154.0
REGS1_k127_5082651_49 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000433 150.0
REGS1_k127_5082651_5 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 6.296e-196 633.0
REGS1_k127_5082651_50 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000003322 136.0
REGS1_k127_5082651_51 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000004224 149.0
REGS1_k127_5082651_52 denitrification pathway - - - 0.0000000000000000000000000000000009294 139.0
REGS1_k127_5082651_53 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000003199 143.0
REGS1_k127_5082651_54 - - - - 0.0000000000000000000000000000002363 138.0
REGS1_k127_5082651_55 Transcriptional regulator, MarR family - - - 0.000000000000000000000000000000501 127.0
REGS1_k127_5082651_56 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000001702 133.0
REGS1_k127_5082651_57 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000006884 119.0
REGS1_k127_5082651_58 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000003887 118.0
REGS1_k127_5082651_59 - - - - 0.000000000000000000000000001304 127.0
REGS1_k127_5082651_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 569.0
REGS1_k127_5082651_60 FMN binding - - - 0.000000000000000000000000007379 119.0
REGS1_k127_5082651_61 4Fe-4S binding domain - - - 0.0000000000000000000000004945 115.0
REGS1_k127_5082651_62 denitrification pathway - - - 0.000000000000000000007189 109.0
REGS1_k127_5082651_63 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000001865 98.0
REGS1_k127_5082651_64 PFAM Transglycosylase-associated protein - - - 0.0000000000000000003408 91.0
REGS1_k127_5082651_65 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000003053 91.0
REGS1_k127_5082651_66 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000004649 75.0
REGS1_k127_5082651_67 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000001918 83.0
REGS1_k127_5082651_68 PHP domain protein - - - 0.00000000000005392 81.0
REGS1_k127_5082651_69 integral membrane protein - - - 0.0000000000007072 76.0
REGS1_k127_5082651_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 527.0
REGS1_k127_5082651_70 denitrification pathway - - - 0.000000000001353 79.0
REGS1_k127_5082651_71 - - - - 0.000000000008215 75.0
REGS1_k127_5082651_72 DNA helicase - - - 0.000000001073 65.0
REGS1_k127_5082651_73 Tautomerase enzyme - - - 0.000008454 53.0
REGS1_k127_5082651_8 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 496.0
REGS1_k127_5082651_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 466.0
REGS1_k127_5372424_0 Chemotaxis protein CheA K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 478.0
REGS1_k127_5372424_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 396.0
REGS1_k127_5372424_10 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000006208 156.0
REGS1_k127_5372424_11 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000009558 133.0
REGS1_k127_5372424_12 PFAM CheW domain protein K03408 - - 0.000000000000000000000001267 112.0
REGS1_k127_5372424_13 VanZ like family - - - 0.0000000000000000002387 92.0
REGS1_k127_5372424_14 PFAM NHL repeat containing protein - - - 0.00000007191 64.0
REGS1_k127_5372424_15 Fibronectin type III domain protein - - - 0.0000005115 64.0
REGS1_k127_5372424_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000001253 276.0
REGS1_k127_5372424_3 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000001189 218.0
REGS1_k127_5372424_4 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000005668 205.0
REGS1_k127_5372424_5 Peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000904 201.0
REGS1_k127_5372424_6 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000194 195.0
REGS1_k127_5372424_7 Chemotaxis protein CheC K03410 - - 0.00000000000000000000000000000000000000000001075 169.0
REGS1_k127_5372424_8 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000001679 163.0
REGS1_k127_5372424_9 PFAM NLP P60 protein K21471 - - 0.0000000000000000000000000000000000000004778 163.0
REGS1_k127_5431737_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 9.017e-260 824.0
REGS1_k127_5431737_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 3.513e-231 742.0
REGS1_k127_5431737_10 permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 430.0
REGS1_k127_5431737_11 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 426.0
REGS1_k127_5431737_12 pfam ammecr1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 382.0
REGS1_k127_5431737_13 histidine kinase DNA gyrase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 361.0
REGS1_k127_5431737_14 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 317.0
REGS1_k127_5431737_15 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 306.0
REGS1_k127_5431737_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002078 274.0
REGS1_k127_5431737_17 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
REGS1_k127_5431737_18 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004123 275.0
REGS1_k127_5431737_19 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 265.0
REGS1_k127_5431737_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.024e-205 656.0
REGS1_k127_5431737_20 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006362 266.0
REGS1_k127_5431737_21 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007742 263.0
REGS1_k127_5431737_22 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
REGS1_k127_5431737_23 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000002127 252.0
REGS1_k127_5431737_24 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000005913 244.0
REGS1_k127_5431737_25 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000008903 222.0
REGS1_k127_5431737_26 G5 - - - 0.000000000000000000000000000000000000000000000000000000000002759 233.0
REGS1_k127_5431737_27 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000001311 221.0
REGS1_k127_5431737_28 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000003258 205.0
REGS1_k127_5431737_29 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000008376 199.0
REGS1_k127_5431737_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 572.0
REGS1_k127_5431737_30 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000009369 207.0
REGS1_k127_5431737_31 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000009163 196.0
REGS1_k127_5431737_32 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000009917 209.0
REGS1_k127_5431737_33 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000001788 184.0
REGS1_k127_5431737_34 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000829 177.0
REGS1_k127_5431737_35 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000001443 168.0
REGS1_k127_5431737_36 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000007788 162.0
REGS1_k127_5431737_37 NLP P60 protein K21471 - - 0.000000000000000000000000000000000000001201 162.0
REGS1_k127_5431737_38 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000768 158.0
REGS1_k127_5431737_39 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.0000000000000000000000000000000000000127 150.0
REGS1_k127_5431737_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 566.0
REGS1_k127_5431737_40 ACT domain protein - - - 0.0000000000000000000000000000000000001715 145.0
REGS1_k127_5431737_41 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000000000000000002065 143.0
REGS1_k127_5431737_42 ACT domain protein - - - 0.000000000000000000000000000000001997 145.0
REGS1_k127_5431737_43 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000008333 146.0
REGS1_k127_5431737_44 Mechanosensitive ion channel - - - 0.0000000000000000000000000000003238 134.0
REGS1_k127_5431737_45 (FHA) domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000000000000000000000000007146 127.0
REGS1_k127_5431737_46 peptidoglycan binding K03642 - - 0.00000000000001751 86.0
REGS1_k127_5431737_47 NUDIX domain - - - 0.00000000000002935 81.0
REGS1_k127_5431737_48 - - - - 0.0000000000001107 79.0
REGS1_k127_5431737_49 - - - - 0.00000000001467 71.0
REGS1_k127_5431737_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 539.0
REGS1_k127_5431737_50 Belongs to the UPF0337 (CsbD) family - - - 0.000000002395 68.0
REGS1_k127_5431737_51 CsbD-like - - - 0.000001175 55.0
REGS1_k127_5431737_52 Diguanylate cyclase, GGDEF domain - - - 0.000003392 58.0
REGS1_k127_5431737_53 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000009512 55.0
REGS1_k127_5431737_54 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0001612 50.0
REGS1_k127_5431737_55 lytic transglycosylase K08307 - - 0.0005322 49.0
REGS1_k127_5431737_56 Prokaryotic N-terminal methylation motif - - - 0.0007364 48.0
REGS1_k127_5431737_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 531.0
REGS1_k127_5431737_7 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 491.0
REGS1_k127_5431737_8 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 479.0
REGS1_k127_5431737_9 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 457.0
REGS1_k127_5491092_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 2.975e-227 713.0
REGS1_k127_5491092_1 Glutamate synthase (NADPH) GltB1 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
REGS1_k127_5491092_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 351.0
REGS1_k127_5491092_3 PFAM glutamate synthase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000625 292.0
REGS1_k127_5491092_4 Signal transduction histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002787 259.0
REGS1_k127_5491092_5 Response regulator receiver K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000004422 226.0
REGS1_k127_5491092_6 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000005002 154.0
REGS1_k127_5491092_7 LysE type translocator - - - 0.0000000000000000000000000001268 131.0
REGS1_k127_5491092_8 - - - - 0.0003691 51.0
REGS1_k127_6068900_0 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 380.0
REGS1_k127_6068900_1 PFAM AAA-4 family protein K02444,K03655 - 3.6.4.12 0.0000000000000000000000000000000000000003082 171.0
REGS1_k127_6068900_2 TIGRFAM transcriptional regulator, AbrB family - - - 0.000000007705 61.0
REGS1_k127_6068900_3 PIN domain K19686 - - 0.00000001655 66.0
REGS1_k127_6222157_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1060.0
REGS1_k127_6222157_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.134e-321 1006.0
REGS1_k127_6222157_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 473.0
REGS1_k127_6222157_11 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 461.0
REGS1_k127_6222157_12 penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 449.0
REGS1_k127_6222157_13 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 451.0
REGS1_k127_6222157_14 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 390.0
REGS1_k127_6222157_15 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 389.0
REGS1_k127_6222157_16 PFAM Signal transduction histidine kinase, osmosensitive K channel sensor, N-terminal K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 372.0
REGS1_k127_6222157_17 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 338.0
REGS1_k127_6222157_18 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 338.0
REGS1_k127_6222157_19 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 344.0
REGS1_k127_6222157_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.794e-286 893.0
REGS1_k127_6222157_20 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 325.0
REGS1_k127_6222157_21 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 319.0
REGS1_k127_6222157_22 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 304.0
REGS1_k127_6222157_23 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
REGS1_k127_6222157_24 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000003057 265.0
REGS1_k127_6222157_25 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003333 250.0
REGS1_k127_6222157_26 Mur ligase, middle domain protein K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000003378 258.0
REGS1_k127_6222157_27 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000008536 234.0
REGS1_k127_6222157_28 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000002535 219.0
REGS1_k127_6222157_29 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000002362 199.0
REGS1_k127_6222157_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.596e-266 836.0
REGS1_k127_6222157_30 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000001693 183.0
REGS1_k127_6222157_31 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000002161 178.0
REGS1_k127_6222157_32 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000004979 177.0
REGS1_k127_6222157_33 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000000003764 167.0
REGS1_k127_6222157_34 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000000000000000000000000001107 166.0
REGS1_k127_6222157_35 Double zinc ribbon - - - 0.00000000000000000000000000000000000002728 149.0
REGS1_k127_6222157_36 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000003162 86.0
REGS1_k127_6222157_38 SMART tyrosine protein kinase K08884 - 2.7.11.1 0.00000002573 63.0
REGS1_k127_6222157_4 Phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 5.431e-258 818.0
REGS1_k127_6222157_41 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00004278 53.0
REGS1_k127_6222157_42 Belongs to the peptidase S26 family - - - 0.0002017 53.0
REGS1_k127_6222157_43 cell adhesion involved in biofilm formation - - - 0.000541 51.0
REGS1_k127_6222157_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 8.272e-212 674.0
REGS1_k127_6222157_6 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 586.0
REGS1_k127_6222157_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 570.0
REGS1_k127_6222157_8 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 556.0
REGS1_k127_6222157_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 512.0
REGS1_k127_6229429_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 3.526e-318 996.0
REGS1_k127_6229429_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.42e-210 701.0
REGS1_k127_6229429_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000007177 188.0
REGS1_k127_6229429_11 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000009783 177.0
REGS1_k127_6229429_12 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000001124 141.0
REGS1_k127_6229429_13 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000675 132.0
REGS1_k127_6229429_14 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.0000000000000000000000000000362 123.0
REGS1_k127_6229429_15 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000003072 87.0
REGS1_k127_6229429_16 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000004243 94.0
REGS1_k127_6229429_17 PFAM CheW domain protein K03408 - - 0.00000000000000007555 92.0
REGS1_k127_6229429_18 PFAM CheW domain protein K03408 - - 0.0000000000000001546 91.0
REGS1_k127_6229429_19 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000001737 77.0
REGS1_k127_6229429_2 Two component signalling adaptor domain K03407,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 471.0
REGS1_k127_6229429_20 regulatory protein, arsR K07755,K21903 - 2.1.1.137 0.000000000000001979 81.0
REGS1_k127_6229429_3 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 293.0
REGS1_k127_6229429_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 290.0
REGS1_k127_6229429_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002332 268.0
REGS1_k127_6229429_6 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000001816 253.0
REGS1_k127_6229429_7 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000003248 224.0
REGS1_k127_6229429_8 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000002542 209.0
REGS1_k127_6229429_9 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000003073 209.0
REGS1_k127_6312389_0 PFAM Glycosyl transferase family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 297.0
REGS1_k127_6312389_1 response regulator - - - 0.00000000000000000000000006203 118.0
REGS1_k127_6312389_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000118 91.0
REGS1_k127_6312389_3 Domain of unknown function DUF11 - - - 0.00000000000154 82.0
REGS1_k127_6312389_4 Bacterial protein of unknown function (DUF916) - - - 0.00001041 57.0
REGS1_k127_6416463_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.417e-302 941.0
REGS1_k127_6416463_1 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001169 288.0
REGS1_k127_6416463_10 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000002532 131.0
REGS1_k127_6416463_12 - - - - 0.000000000001748 75.0
REGS1_k127_6416463_13 Short C-terminal domain K08982 - - 0.0005322 47.0
REGS1_k127_6416463_2 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009045 250.0
REGS1_k127_6416463_3 pfam abc1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004822 257.0
REGS1_k127_6416463_4 short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003342 250.0
REGS1_k127_6416463_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000209 236.0
REGS1_k127_6416463_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000002553 194.0
REGS1_k127_6416463_7 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000002407 170.0
REGS1_k127_6416463_8 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000006388 152.0
REGS1_k127_6416463_9 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000004355 134.0
REGS1_k127_6977751_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.807e-226 712.0
REGS1_k127_6977751_1 ATPases associated with a variety of cellular activities K10441,K10542 - 3.6.3.17 2.813e-205 650.0
REGS1_k127_6977751_10 Short-chain dehydrogenase reductase sdr K00059,K20900 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0047880,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 1.1.1.100,1.1.1.403 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
REGS1_k127_6977751_11 ABC transporter K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 280.0
REGS1_k127_6977751_12 Ribose/Galactose Isomerase K01808 GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000001144 229.0
REGS1_k127_6977751_13 EDD domain protein, DegV family - - - 0.0000000000000000000000000000000000000000000001248 180.0
REGS1_k127_6977751_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004675 170.0
REGS1_k127_6977751_15 PIN domain - - - 0.00000000000004525 77.0
REGS1_k127_6977751_16 - K21495 - - 0.0005539 47.0
REGS1_k127_6977751_2 PFAM Dak kinase K00863,K05878,K20902 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0030246,GO:0042221,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 2.7.1.121,2.7.1.210,2.7.1.28,2.7.1.29,4.6.1.15 5.224e-201 642.0
REGS1_k127_6977751_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 481.0
REGS1_k127_6977751_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 483.0
REGS1_k127_6977751_5 Periplasmic binding protein LacI transcriptional regulator K10439,K17213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 480.0
REGS1_k127_6977751_6 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 445.0
REGS1_k127_6977751_7 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 415.0
REGS1_k127_6977751_8 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 403.0
REGS1_k127_6977751_9 Branched-chain amino acid transport system / permease component K10544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 402.0
REGS1_k127_7037973_0 Putative glucoamylase K13688 - - 0.0 2440.0
REGS1_k127_7037973_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1119.0
REGS1_k127_7037973_10 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 352.0
REGS1_k127_7037973_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 344.0
REGS1_k127_7037973_12 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
REGS1_k127_7037973_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 305.0
REGS1_k127_7037973_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 295.0
REGS1_k127_7037973_15 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
REGS1_k127_7037973_16 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 281.0
REGS1_k127_7037973_17 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001322 244.0
REGS1_k127_7037973_18 TIGRFAM L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000004859 224.0
REGS1_k127_7037973_19 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000003212 221.0
REGS1_k127_7037973_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.634e-263 825.0
REGS1_k127_7037973_20 PDZ DHR GLGF domain protein K08372 - - 0.0000000000000000000000000000000000000000000000000000000006802 218.0
REGS1_k127_7037973_21 R3H domain K06346 - - 0.0000000000000000000000000000000000000000000000000000003078 201.0
REGS1_k127_7037973_22 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000001935 209.0
REGS1_k127_7037973_23 IA, variant 3 K06019 - 3.6.1.1 0.000000000000000000000000000000000000000000000000003479 189.0
REGS1_k127_7037973_24 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000003388 181.0
REGS1_k127_7037973_25 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.000000000000000000000000000000000000000000002231 178.0
REGS1_k127_7037973_26 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000007099 156.0
REGS1_k127_7037973_27 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000002357 158.0
REGS1_k127_7037973_28 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000009149 139.0
REGS1_k127_7037973_29 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000004201 149.0
REGS1_k127_7037973_3 P-type ATPase K01537 - 3.6.3.8 3.805e-218 709.0
REGS1_k127_7037973_30 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001431 116.0
REGS1_k127_7037973_31 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000001612 86.0
REGS1_k127_7037973_32 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000004958 94.0
REGS1_k127_7037973_33 COG0607 Rhodanese-related sulfurtransferase K03972 - - 0.000000000000005844 85.0
REGS1_k127_7037973_34 PFAM FeoA domain K04758 - - 0.000000000000006868 78.0
REGS1_k127_7037973_35 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000003887 72.0
REGS1_k127_7037973_36 - - - - 0.000000000001661 75.0
REGS1_k127_7037973_37 Acetyltransferase (GNAT) family - - - 0.00000000002884 72.0
REGS1_k127_7037973_38 - - - - 0.00000002078 62.0
REGS1_k127_7037973_39 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K06196 - - 0.0000001012 56.0
REGS1_k127_7037973_4 Belongs to the 5'-nucleotidase family - - - 1.422e-206 654.0
REGS1_k127_7037973_40 - - - - 0.00001435 50.0
REGS1_k127_7037973_41 - - - - 0.00003024 47.0
REGS1_k127_7037973_42 gas vesicle protein - - - 0.0002368 47.0
REGS1_k127_7037973_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.679e-206 658.0
REGS1_k127_7037973_6 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 574.0
REGS1_k127_7037973_7 Bacterial dnaA protein helix-turn-helix domain K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 477.0
REGS1_k127_7037973_8 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 440.0
REGS1_k127_7037973_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 395.0
REGS1_k127_7109148_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.345e-248 790.0
REGS1_k127_7109148_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.205e-231 729.0
REGS1_k127_7109148_10 RIP metalloprotease RseP K11749 - - 0.000000000000000000000000000000000000000000000000000000000001098 226.0
REGS1_k127_7109148_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000001234 232.0
REGS1_k127_7109148_12 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000009164 200.0
REGS1_k127_7109148_13 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000003525 171.0
REGS1_k127_7109148_14 - - - - 0.0000000000000000000000000000000000001531 147.0
REGS1_k127_7109148_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000001153 143.0
REGS1_k127_7109148_16 AMP binding - - - 0.000000000000000000000003844 110.0
REGS1_k127_7109148_17 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.000000000000000000004757 95.0
REGS1_k127_7109148_18 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000005285 92.0
REGS1_k127_7109148_19 - - - - 0.0000000000000004062 82.0
REGS1_k127_7109148_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.649e-208 662.0
REGS1_k127_7109148_20 Protein of unknown function, DUF485 - - - 0.000000000000002306 90.0
REGS1_k127_7109148_21 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000003842 84.0
REGS1_k127_7109148_3 glycolate transport K14393 - - 2.31e-205 658.0
REGS1_k127_7109148_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 450.0
REGS1_k127_7109148_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 435.0
REGS1_k127_7109148_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 385.0
REGS1_k127_7109148_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 356.0
REGS1_k127_7109148_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 280.0
REGS1_k127_7109148_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
REGS1_k127_7161690_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1387.0
REGS1_k127_7161690_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 504.0
REGS1_k127_7161690_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 461.0
REGS1_k127_7161690_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 314.0
REGS1_k127_7161690_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000003075 70.0
REGS1_k127_7212502_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 545.0
REGS1_k127_7212502_1 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 426.0
REGS1_k127_7212502_10 - - - - 0.00000000000005207 78.0
REGS1_k127_7212502_2 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 382.0
REGS1_k127_7212502_3 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 354.0
REGS1_k127_7212502_4 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 349.0
REGS1_k127_7212502_5 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000295 279.0
REGS1_k127_7212502_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000003388 261.0
REGS1_k127_7212502_7 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
REGS1_k127_7212502_8 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000006972 192.0
REGS1_k127_7212502_9 Transcriptional regulator PadR-like family - - - 0.0000000000000000001509 92.0
REGS1_k127_7411017_0 DNA helicase K03657 - 3.6.4.12 2.326e-237 757.0
REGS1_k127_7411017_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.134e-230 726.0
REGS1_k127_7411017_10 DHHA2 domain protein K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 405.0
REGS1_k127_7411017_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
REGS1_k127_7411017_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 373.0
REGS1_k127_7411017_13 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 370.0
REGS1_k127_7411017_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 334.0
REGS1_k127_7411017_15 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 316.0
REGS1_k127_7411017_16 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009885 292.0
REGS1_k127_7411017_17 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002648 273.0
REGS1_k127_7411017_18 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000004674 249.0
REGS1_k127_7411017_19 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
REGS1_k127_7411017_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 9.757e-221 698.0
REGS1_k127_7411017_20 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000002087 233.0
REGS1_k127_7411017_21 Response regulator receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000176 238.0
REGS1_k127_7411017_22 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000006904 252.0
REGS1_k127_7411017_23 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001492 222.0
REGS1_k127_7411017_24 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000003312 237.0
REGS1_k127_7411017_25 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000001419 237.0
REGS1_k127_7411017_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000002057 228.0
REGS1_k127_7411017_27 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
REGS1_k127_7411017_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000001455 201.0
REGS1_k127_7411017_29 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000001658 192.0
REGS1_k127_7411017_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.402e-217 691.0
REGS1_k127_7411017_30 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000003353 183.0
REGS1_k127_7411017_31 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000007076 168.0
REGS1_k127_7411017_32 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000007604 172.0
REGS1_k127_7411017_33 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000001809 176.0
REGS1_k127_7411017_34 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000001716 164.0
REGS1_k127_7411017_35 PFAM CBS domain - - - 0.000000000000000000000000000000000000001067 153.0
REGS1_k127_7411017_36 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000001977 147.0
REGS1_k127_7411017_37 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000006721 151.0
REGS1_k127_7411017_38 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000000647 141.0
REGS1_k127_7411017_39 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000002359 134.0
REGS1_k127_7411017_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 8.022e-217 681.0
REGS1_k127_7411017_40 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000001576 136.0
REGS1_k127_7411017_41 Chorismate mutase type II - - - 0.000000000000000000001502 99.0
REGS1_k127_7411017_42 Zinc finger cdgsh-type domain protein - - - 0.000000000000000000003927 96.0
REGS1_k127_7411017_43 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000001046 94.0
REGS1_k127_7411017_44 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001264 78.0
REGS1_k127_7411017_45 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000005343 73.0
REGS1_k127_7411017_46 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000003393 74.0
REGS1_k127_7411017_48 ATP synthase subunit C K02124 - - 0.0000168 51.0
REGS1_k127_7411017_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.084e-204 668.0
REGS1_k127_7411017_6 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 554.0
REGS1_k127_7411017_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 473.0
REGS1_k127_7411017_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070,K03789,K14742 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004596,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006473,GO:0006474,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008999,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0030312,GO:0031365,GO:0032991,GO:0034212,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051604,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.128,2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 482.0
REGS1_k127_7411017_9 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 472.0
REGS1_k127_7472971_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 606.0
REGS1_k127_7472971_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 582.0
REGS1_k127_7472971_10 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000002772 171.0
REGS1_k127_7472971_11 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000008353 136.0
REGS1_k127_7472971_12 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000001387 125.0
REGS1_k127_7472971_13 PFAM OsmC-like protein K07397 - - 0.000000000000000000000000009617 115.0
REGS1_k127_7472971_14 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000007636 90.0
REGS1_k127_7472971_15 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000006433 64.0
REGS1_k127_7472971_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 504.0
REGS1_k127_7472971_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 417.0
REGS1_k127_7472971_4 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 413.0
REGS1_k127_7472971_5 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 370.0
REGS1_k127_7472971_6 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000001657 217.0
REGS1_k127_7472971_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000009321 214.0
REGS1_k127_7472971_8 Cytochrome b/b6/petB K03620 - - 0.000000000000000000000000000000000000000000000000000001013 199.0
REGS1_k127_7472971_9 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000002285 193.0
REGS1_k127_7610508_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 2.774e-268 850.0
REGS1_k127_7610508_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.617e-264 834.0
REGS1_k127_7610508_10 PFAM LOR SDH bifunctional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
REGS1_k127_7610508_11 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 436.0
REGS1_k127_7610508_12 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 417.0
REGS1_k127_7610508_13 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 412.0
REGS1_k127_7610508_14 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 410.0
REGS1_k127_7610508_15 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 403.0
REGS1_k127_7610508_16 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 411.0
REGS1_k127_7610508_17 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 389.0
REGS1_k127_7610508_18 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 360.0
REGS1_k127_7610508_19 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 337.0
REGS1_k127_7610508_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.231e-230 728.0
REGS1_k127_7610508_20 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 GO:0001522,GO:0003674,GO:0003824,GO:0004730,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016043,GO:0016070,GO:0016787,GO:0016798,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0030145,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0090304,GO:1901360 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 351.0
REGS1_k127_7610508_21 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 325.0
REGS1_k127_7610508_22 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 323.0
REGS1_k127_7610508_23 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 320.0
REGS1_k127_7610508_24 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 307.0
REGS1_k127_7610508_25 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 288.0
REGS1_k127_7610508_26 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002561 293.0
REGS1_k127_7610508_27 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001541 276.0
REGS1_k127_7610508_28 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000003045 270.0
REGS1_k127_7610508_29 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004501 241.0
REGS1_k127_7610508_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.405e-194 615.0
REGS1_k127_7610508_30 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000173 232.0
REGS1_k127_7610508_31 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000004196 233.0
REGS1_k127_7610508_32 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000004144 233.0
REGS1_k127_7610508_33 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000003172 195.0
REGS1_k127_7610508_34 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000249 192.0
REGS1_k127_7610508_35 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000003716 192.0
REGS1_k127_7610508_36 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000003856 205.0
REGS1_k127_7610508_37 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000005343 184.0
REGS1_k127_7610508_38 Winged helix-turn-helix DNA-binding K00852,K16328 - 2.7.1.15,2.7.1.83 0.000000000000000000000000000000000000000000000007331 184.0
REGS1_k127_7610508_39 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000002487 187.0
REGS1_k127_7610508_4 Sulfate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 605.0
REGS1_k127_7610508_40 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000002544 181.0
REGS1_k127_7610508_41 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000007801 175.0
REGS1_k127_7610508_42 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000191 189.0
REGS1_k127_7610508_43 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000157 161.0
REGS1_k127_7610508_44 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000004557 161.0
REGS1_k127_7610508_45 Condensation domain - - - 0.0000000000000000000000000000000000000004822 165.0
REGS1_k127_7610508_46 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000004517 153.0
REGS1_k127_7610508_47 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000004557 159.0
REGS1_k127_7610508_48 EamA-like transporter family - - - 0.00000000000000000000000000000000001811 146.0
REGS1_k127_7610508_49 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000002883 139.0
REGS1_k127_7610508_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 580.0
REGS1_k127_7610508_50 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000005485 142.0
REGS1_k127_7610508_51 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000008819 138.0
REGS1_k127_7610508_53 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000005554 122.0
REGS1_k127_7610508_54 domain, Protein - - - 0.000000000000000000000000000007992 137.0
REGS1_k127_7610508_55 N-terminal domain of toast_rack, DUF2154 - - - 0.000000000000000000000000000008318 128.0
REGS1_k127_7610508_56 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000001654 129.0
REGS1_k127_7610508_57 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000006276 130.0
REGS1_k127_7610508_58 - - - - 0.0000000000000000000000000626 116.0
REGS1_k127_7610508_59 RmlD substrate binding domain - - - 0.0000000000000000000000002991 118.0
REGS1_k127_7610508_6 PFAM cation transporter K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 550.0
REGS1_k127_7610508_60 - - - - 0.0000000000000000000000006867 115.0
REGS1_k127_7610508_61 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.0000000000000000000000009863 120.0
REGS1_k127_7610508_62 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000006404 112.0
REGS1_k127_7610508_63 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000008148 121.0
REGS1_k127_7610508_64 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000001876 118.0
REGS1_k127_7610508_65 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000002154 98.0
REGS1_k127_7610508_66 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.0000000000000000001036 103.0
REGS1_k127_7610508_67 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000005007 91.0
REGS1_k127_7610508_68 Protein of unknown function (DUF1461) - - - 0.000000000000000003073 94.0
REGS1_k127_7610508_69 PFAM SpoVT AbrB domain protein K07172 - - 0.0000000000000006091 84.0
REGS1_k127_7610508_7 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 521.0
REGS1_k127_7610508_70 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000004712 79.0
REGS1_k127_7610508_71 Nitrous oxide-stimulated promoter - - - 0.00000000000001218 79.0
REGS1_k127_7610508_72 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.00000000000001228 82.0
REGS1_k127_7610508_73 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000003436 81.0
REGS1_k127_7610508_74 PFAM Peptidase family M28 - - - 0.0000000000003055 83.0
REGS1_k127_7610508_75 peptidase U32 - - - 0.0000000000003057 72.0
REGS1_k127_7610508_76 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000004596 79.0
REGS1_k127_7610508_77 PFAM secretion protein HlyD family protein K01993 - - 0.000000000006728 77.0
REGS1_k127_7610508_79 Bacterial regulatory proteins, tetR family - - - 0.0000000000657 75.0
REGS1_k127_7610508_8 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 514.0
REGS1_k127_7610508_81 - - - - 0.0000000005971 73.0
REGS1_k127_7610508_82 - - - - 0.000000001433 71.0
REGS1_k127_7610508_83 Matrixin - - - 0.000000001491 72.0
REGS1_k127_7610508_84 - - - - 0.00000003982 64.0
REGS1_k127_7610508_85 - - - - 0.00000005679 63.0
REGS1_k127_7610508_86 - - - - 0.0000002903 60.0
REGS1_k127_7610508_87 Cellulose binding domain K07004 - - 0.000001465 62.0
REGS1_k127_7610508_89 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00005363 55.0
REGS1_k127_7610508_9 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 479.0
REGS1_k127_8147856_0 Radical SAM K22226 - - 2.817e-219 687.0
REGS1_k127_8147856_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 581.0
REGS1_k127_8147856_10 - - - - 0.000000000003068 68.0
REGS1_k127_8147856_11 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.0000000001534 61.0
REGS1_k127_8147856_12 PFAM Cytochrome c assembly protein - - - 0.0000000005763 70.0
REGS1_k127_8147856_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 467.0
REGS1_k127_8147856_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 423.0
REGS1_k127_8147856_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 330.0
REGS1_k127_8147856_5 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
REGS1_k127_8147856_6 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001556 226.0
REGS1_k127_8147856_7 heme exporter protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000009934 225.0
REGS1_k127_8147856_8 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000485 221.0
REGS1_k127_8147856_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
REGS1_k127_8237466_0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 529.0
REGS1_k127_8237466_1 PFAM Glycosyl transferase, group 1 K06338,K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000001576 264.0
REGS1_k127_8237466_2 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 261.0
REGS1_k127_8237466_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005864 259.0
REGS1_k127_8237466_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000007016 200.0
REGS1_k127_8237466_5 heat shock protein binding - - - 0.000000000000000000000000000000001183 145.0
REGS1_k127_8237466_6 PFAM PKD domain containing protein - - - 0.000000000000000000000000000004132 141.0
REGS1_k127_8237466_7 PFAM Glycosyl transferase family 2 - - - 0.000000004404 60.0
REGS1_k127_8237466_8 O-Antigen ligase - - - 0.00000001675 68.0
REGS1_k127_8237466_9 Tetratricopeptide repeat - - - 0.000001638 59.0
REGS1_k127_826454_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0 1086.0
REGS1_k127_826454_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 4.999e-292 921.0
REGS1_k127_826454_10 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 490.0
REGS1_k127_826454_11 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 434.0
REGS1_k127_826454_12 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 389.0
REGS1_k127_826454_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 377.0
REGS1_k127_826454_14 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 349.0
REGS1_k127_826454_15 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
REGS1_k127_826454_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 291.0
REGS1_k127_826454_17 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000172 292.0
REGS1_k127_826454_18 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
REGS1_k127_826454_19 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
REGS1_k127_826454_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.017e-275 868.0
REGS1_k127_826454_20 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
REGS1_k127_826454_21 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000002132 246.0
REGS1_k127_826454_22 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000002332 242.0
REGS1_k127_826454_23 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000655 231.0
REGS1_k127_826454_24 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000008457 207.0
REGS1_k127_826454_25 domain protein - - - 0.000000000000000000000000000000000000000000000000000001633 198.0
REGS1_k127_826454_26 Conserved hypothetical ATP binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000001671 196.0
REGS1_k127_826454_27 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000001089 193.0
REGS1_k127_826454_28 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000001176 202.0
REGS1_k127_826454_29 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000008843 182.0
REGS1_k127_826454_3 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 1.369e-266 836.0
REGS1_k127_826454_30 HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668 K07015 - - 0.000000000000000000000000000000000000002295 153.0
REGS1_k127_826454_31 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000002501 156.0
REGS1_k127_826454_32 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000123 140.0
REGS1_k127_826454_33 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000001973 134.0
REGS1_k127_826454_34 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000001262 138.0
REGS1_k127_826454_35 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000718 125.0
REGS1_k127_826454_36 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000001665 98.0
REGS1_k127_826454_37 Asp23 family, cell envelope-related function - - - 0.00000000000000000007956 93.0
REGS1_k127_826454_39 Preprotein translocase subunit K03210 - - 0.0000000000001731 74.0
REGS1_k127_826454_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.982e-216 686.0
REGS1_k127_826454_40 carbon utilization K02664,K02665,K12280 - - 0.000000000002498 75.0
REGS1_k127_826454_41 PFAM Fimbrial assembly family protein K02663 - - 0.0000000003192 69.0
REGS1_k127_826454_42 Pfam:N_methyl_2 - - - 0.00000006332 60.0
REGS1_k127_826454_43 Bacterial protein of unknown function (DUF948) - - - 0.000003341 55.0
REGS1_k127_826454_44 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000005058 57.0
REGS1_k127_826454_45 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00002681 51.0
REGS1_k127_826454_5 General secretory system II, protein E domain protein K02652 - - 3.977e-201 643.0
REGS1_k127_826454_6 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 597.0
REGS1_k127_826454_7 type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 584.0
REGS1_k127_826454_8 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 548.0
REGS1_k127_826454_9 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 514.0
REGS1_k127_8303787_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1246.0
REGS1_k127_8303787_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.477e-221 706.0
REGS1_k127_8303787_10 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000001076 250.0
REGS1_k127_8303787_11 PFAM Membrane protein of K08972 - - 0.0000000000001015 76.0
REGS1_k127_8303787_12 Preprotein translocase SecG subunit K03075 - - 0.0000000000009499 70.0
REGS1_k127_8303787_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000007965 79.0
REGS1_k127_8303787_14 - - - - 0.00007291 53.0
REGS1_k127_8303787_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 578.0
REGS1_k127_8303787_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 488.0
REGS1_k127_8303787_4 pathway, signal sequence K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 492.0
REGS1_k127_8303787_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 478.0
REGS1_k127_8303787_6 May be required for sporulation K09762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 376.0
REGS1_k127_8303787_7 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 310.0
REGS1_k127_8303787_8 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 318.0
REGS1_k127_8303787_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001092 279.0
REGS1_k127_8331858_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 1.46e-261 833.0
REGS1_k127_8331858_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.401e-259 832.0
REGS1_k127_8331858_10 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000001472 121.0
REGS1_k127_8331858_11 regulatory protein, arsR K21903 - - 0.000000000000000000000003887 106.0
REGS1_k127_8331858_12 Response regulator receiver - - - 0.00000000000000000000001855 108.0
REGS1_k127_8331858_13 COG0500 SAM-dependent methyltransferases K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000003305 103.0
REGS1_k127_8331858_14 - - - - 0.000000004474 71.0
REGS1_k127_8331858_15 PFAM glutamate synthase alpha subunit - - - 0.0000006155 51.0
REGS1_k127_8331858_17 Protein of unknown function (DUF3616) - - - 0.00002262 59.0
REGS1_k127_8331858_18 Fibronectin type III domain protein - - - 0.00002262 59.0
REGS1_k127_8331858_19 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00003921 58.0
REGS1_k127_8331858_2 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 9.551e-201 635.0
REGS1_k127_8331858_20 regulator of chromosome condensation, RCC1 - - - 0.0004661 54.0
REGS1_k127_8331858_3 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 564.0
REGS1_k127_8331858_4 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 551.0
REGS1_k127_8331858_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 418.0
REGS1_k127_8331858_6 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000001957 205.0
REGS1_k127_8331858_7 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000000005661 191.0
REGS1_k127_8331858_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000005737 164.0
REGS1_k127_8331858_9 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000004728 134.0
REGS1_k127_8418112_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 293.0
REGS1_k127_8418112_1 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000008998 150.0
REGS1_k127_8585877_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1119.0
REGS1_k127_8585877_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 5.215e-203 654.0
REGS1_k127_8585877_10 Integral membrane protein (Pin domain superfamily) - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001381 264.0
REGS1_k127_8585877_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
REGS1_k127_8585877_12 PFAM sigma-70 region 2 domain protein K03091 - - 0.000000000000000000000000000000000000000000000000000000000000002381 225.0
REGS1_k127_8585877_13 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000004501 231.0
REGS1_k127_8585877_14 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000001347 213.0
REGS1_k127_8585877_15 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
REGS1_k127_8585877_16 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000004509 200.0
REGS1_k127_8585877_17 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000001557 198.0
REGS1_k127_8585877_18 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000001079 192.0
REGS1_k127_8585877_19 Belongs to the peptidase M50B family K06402 - - 0.00000000000000000000000000000000000000000000003969 186.0
REGS1_k127_8585877_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 497.0
REGS1_k127_8585877_20 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000002387 174.0
REGS1_k127_8585877_21 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000007026 160.0
REGS1_k127_8585877_22 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000005067 154.0
REGS1_k127_8585877_23 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000002871 132.0
REGS1_k127_8585877_24 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000009019 107.0
REGS1_k127_8585877_25 YacP-like NYN domain K06962 - - 0.0000000000000000000001012 104.0
REGS1_k127_8585877_26 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000001397 107.0
REGS1_k127_8585877_27 VanZ like family - - - 0.00000000000000005493 85.0
REGS1_k127_8585877_28 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000008929 88.0
REGS1_k127_8585877_29 NACHT domain - - - 0.000000000004479 79.0
REGS1_k127_8585877_3 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 434.0
REGS1_k127_8585877_30 protein folding in endoplasmic reticulum K19134 - - 0.00000000002616 74.0
REGS1_k127_8585877_32 EamA-like transporter family - - - 0.000002731 59.0
REGS1_k127_8585877_34 - - - - 0.00006219 47.0
REGS1_k127_8585877_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 424.0
REGS1_k127_8585877_5 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 386.0
REGS1_k127_8585877_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 356.0
REGS1_k127_8585877_7 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 335.0
REGS1_k127_8585877_8 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 304.0
REGS1_k127_8585877_9 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000861 266.0
REGS1_k127_8919572_0 elongation factor G K02355 - - 3.222e-256 811.0
REGS1_k127_8919572_1 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 458.0
REGS1_k127_8919572_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000006306 148.0
REGS1_k127_8919572_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000009178 102.0
REGS1_k127_8919572_12 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000002774 79.0
REGS1_k127_8919572_2 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 421.0
REGS1_k127_8919572_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 349.0
REGS1_k127_8919572_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005611 253.0
REGS1_k127_8919572_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000003111 205.0
REGS1_k127_8919572_6 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000000000000000000000000000000000000003144 206.0
REGS1_k127_8919572_7 - - - - 0.000000000000000000000000000000000000000000002977 181.0
REGS1_k127_8919572_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000002101 184.0
REGS1_k127_8919572_9 DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000006755 170.0
REGS1_k127_9111933_0 Radical SAM domain protein - - - 4.693e-208 679.0
REGS1_k127_9111933_1 Cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 485.0
REGS1_k127_9111933_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000002065 235.0
REGS1_k127_9111933_11 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000007883 235.0
REGS1_k127_9111933_12 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000003742 196.0
REGS1_k127_9111933_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000006561 199.0
REGS1_k127_9111933_14 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000001319 190.0
REGS1_k127_9111933_15 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000003356 186.0
REGS1_k127_9111933_16 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000142 179.0
REGS1_k127_9111933_17 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000003921 175.0
REGS1_k127_9111933_18 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000002914 148.0
REGS1_k127_9111933_19 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000002141 133.0
REGS1_k127_9111933_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 486.0
REGS1_k127_9111933_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001632 140.0
REGS1_k127_9111933_21 Hydrolase HD family - - - 0.000000000000000000000000000011 129.0
REGS1_k127_9111933_22 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000003139 114.0
REGS1_k127_9111933_23 FMN_bind K03612 - - 0.000000000000000006473 91.0
REGS1_k127_9111933_24 NusG domain II - - - 0.0000000000001919 74.0
REGS1_k127_9111933_25 rod shape-determining protein (MreD) K03571 - - 0.000000000001781 79.0
REGS1_k127_9111933_26 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000001727 67.0
REGS1_k127_9111933_27 Cell envelope-related transcriptional attenuator domain - - - 0.000004843 59.0
REGS1_k127_9111933_29 Belongs to the glycosyl hydrolase family 6 K01218 - 3.2.1.78 0.0006047 49.0
REGS1_k127_9111933_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 453.0
REGS1_k127_9111933_4 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 460.0
REGS1_k127_9111933_5 ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 424.0
REGS1_k127_9111933_6 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 411.0
REGS1_k127_9111933_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
REGS1_k127_9111933_8 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 324.0
REGS1_k127_9111933_9 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000001576 257.0