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Overview

ID MAG03319
Name REGS1_bin.58
Sample SMP0079
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Terriglobales
Family JAIQGF01
Genus JAIQGF01
Species
Assembly information
Completeness (%) 79.13
Contamination (%) 4.5
GC content (%) 63.0
N50 (bp) 11,243
Genome size (bp) 2,732,713

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2416

Gene name Description KEGG GOs EC E-value Score Sequence
REGS1_k127_108009_0 Acyl transferase domain - - - 0.0 2281.0
REGS1_k127_108009_1 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 542.0
REGS1_k127_109041_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 596.0
REGS1_k127_109041_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 505.0
REGS1_k127_109041_2 PFAM nitrite and sulphite reductase 4Fe-4S K00392 - 1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 414.0
REGS1_k127_109041_3 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000002338 258.0
REGS1_k127_109041_4 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000004503 171.0
REGS1_k127_1152371_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 420.0
REGS1_k127_1152371_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 295.0
REGS1_k127_1152371_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000297 202.0
REGS1_k127_1152371_3 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000007627 203.0
REGS1_k127_1152371_4 - - - - 0.000000000000000000000000000000000000000000000000001353 191.0
REGS1_k127_1157262_0 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 424.0
REGS1_k127_1157262_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001255 168.0
REGS1_k127_1157262_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000007396 97.0
REGS1_k127_1161912_0 Sortilin, neurotensin receptor 3, - - - 0.0 1385.0
REGS1_k127_1161912_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.212e-279 879.0
REGS1_k127_1161912_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.232e-216 690.0
REGS1_k127_1161912_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 505.0
REGS1_k127_1161912_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 458.0
REGS1_k127_1161912_5 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 391.0
REGS1_k127_1161912_6 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 392.0
REGS1_k127_1161912_7 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
REGS1_k127_1161912_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000003101 235.0
REGS1_k127_1161912_9 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000002262 120.0
REGS1_k127_1176110_0 FAE1/Type III polyketide synthase-like protein K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 455.0
REGS1_k127_1176110_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 452.0
REGS1_k127_1176110_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
REGS1_k127_1176110_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000001639 179.0
REGS1_k127_1176110_4 - - - - 0.000000000001421 76.0
REGS1_k127_1179563_0 Carboxypeptidase regulatory-like domain - - - 4.917e-243 790.0
REGS1_k127_1179563_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000007691 244.0
REGS1_k127_1179563_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000002256 151.0
REGS1_k127_1179563_3 - - - - 0.0000000000000000000000000000000008484 139.0
REGS1_k127_1196358_0 ABC transporter K11085 - - 2.996e-261 818.0
REGS1_k127_1196358_1 lipopolysaccharide transport K09774 - - 5.613e-226 723.0
REGS1_k127_1196358_10 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 399.0
REGS1_k127_1196358_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 323.0
REGS1_k127_1196358_12 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
REGS1_k127_1196358_13 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009557 278.0
REGS1_k127_1196358_14 Ribosomal subunit interface protein K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000009362 227.0
REGS1_k127_1196358_15 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000000000194 163.0
REGS1_k127_1196358_16 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000001383 116.0
REGS1_k127_1196358_17 - - - - 0.00000000000000000000003736 102.0
REGS1_k127_1196358_18 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000002054 98.0
REGS1_k127_1196358_2 RNA polymerase sigma-54 factor K03092 - - 5.832e-226 717.0
REGS1_k127_1196358_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 560.0
REGS1_k127_1196358_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 526.0
REGS1_k127_1196358_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 478.0
REGS1_k127_1196358_6 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 414.0
REGS1_k127_1196358_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
REGS1_k127_1196358_8 Binding-protein-dependent transport system inner membrane component K02025,K10118,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 413.0
REGS1_k127_1196358_9 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 400.0
REGS1_k127_1200712_0 heat shock protein 70 K04043,K04044 - - 6.29e-321 991.0
REGS1_k127_1200712_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.917e-216 677.0
REGS1_k127_1200712_10 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000000000000004241 193.0
REGS1_k127_1200712_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000008536 194.0
REGS1_k127_1200712_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000004582 185.0
REGS1_k127_1200712_13 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000000000000000005596 176.0
REGS1_k127_1200712_14 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000009142 153.0
REGS1_k127_1200712_15 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000001336 147.0
REGS1_k127_1200712_17 FeS assembly protein IscX - - - 0.000000000000000000000000008225 117.0
REGS1_k127_1200712_18 amine dehydrogenase activity - - - 0.00000000000000000000000007158 120.0
REGS1_k127_1200712_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
REGS1_k127_1200712_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 421.0
REGS1_k127_1200712_4 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 318.0
REGS1_k127_1200712_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002898 278.0
REGS1_k127_1200712_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006255 276.0
REGS1_k127_1200712_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000197 246.0
REGS1_k127_1200712_8 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001133 246.0
REGS1_k127_1200712_9 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000001556 201.0
REGS1_k127_1202404_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1109.0
REGS1_k127_1202404_1 Histidine kinase K02482,K03557 - 2.7.13.3 0.0 1092.0
REGS1_k127_1202404_10 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
REGS1_k127_1202404_11 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 297.0
REGS1_k127_1202404_12 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002242 272.0
REGS1_k127_1202404_13 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004441 290.0
REGS1_k127_1202404_14 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001296 269.0
REGS1_k127_1202404_15 cellular response to heat K09807 - - 0.000000000000000000000000000000000000000000000000000000000000000000009213 241.0
REGS1_k127_1202404_16 multi-organism process K03195 - - 0.00000000000000000000000000000000000000000000000000000000000000009879 229.0
REGS1_k127_1202404_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000185 219.0
REGS1_k127_1202404_19 iron ion homeostasis K05349 - 3.2.1.21 0.0000000000000000000000000000000000000194 154.0
REGS1_k127_1202404_2 Protein of unknown function (DUF1343) - - - 4.777e-305 955.0
REGS1_k127_1202404_20 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000004675 145.0
REGS1_k127_1202404_21 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000000000000000003021 130.0
REGS1_k127_1202404_23 domain, Protein K02450,K07126,K15539 - - 0.00000000000000006722 93.0
REGS1_k127_1202404_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.637e-250 778.0
REGS1_k127_1202404_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.54e-224 700.0
REGS1_k127_1202404_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.279e-196 617.0
REGS1_k127_1202404_6 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 592.0
REGS1_k127_1202404_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 464.0
REGS1_k127_1202404_8 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 381.0
REGS1_k127_1202404_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 357.0
REGS1_k127_124480_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 7.47e-230 734.0
REGS1_k127_124480_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 5.447e-212 668.0
REGS1_k127_124480_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.542e-205 659.0
REGS1_k127_124480_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009158 273.0
REGS1_k127_124480_4 ASPIC and UnbV - - - 0.00000000000000000000000000000000000007957 144.0
REGS1_k127_124480_5 - - - - 0.000000000000000000000000000000002644 139.0
REGS1_k127_124480_6 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000003872 76.0
REGS1_k127_124480_7 - - - - 0.0000004209 55.0
REGS1_k127_1257008_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 462.0
REGS1_k127_1257008_1 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 362.0
REGS1_k127_1257008_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
REGS1_k127_1257008_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000001077 211.0
REGS1_k127_1257008_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000009614 181.0
REGS1_k127_1257008_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000002782 168.0
REGS1_k127_1257008_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000861 66.0
REGS1_k127_1283424_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1021.0
REGS1_k127_1283424_1 Permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 289.0
REGS1_k127_1284877_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000003162 98.0
REGS1_k127_1284877_1 PFAM ABC-2 type transporter K01992 - - 0.00000000005182 70.0
REGS1_k127_1284877_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000001585 61.0
REGS1_k127_1286694_0 TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 357.0
REGS1_k127_1286694_1 Glycosyl hydrolase family 20, domain 2 - - - 0.0000000000000000000003006 112.0
REGS1_k127_1290538_0 virulence factor MVIN family protein K03980 - - 4.127e-211 669.0
REGS1_k127_1290538_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 546.0
REGS1_k127_1290538_2 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000002849 233.0
REGS1_k127_1306909_0 Ribosomal protein S1 K02945 - - 6.143e-303 942.0
REGS1_k127_1306909_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 597.0
REGS1_k127_1306909_10 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000001593 104.0
REGS1_k127_1306909_12 - K05826 - - 0.00000000000261 68.0
REGS1_k127_1306909_13 - - - - 0.000001355 54.0
REGS1_k127_1306909_2 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 524.0
REGS1_k127_1306909_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 314.0
REGS1_k127_1306909_4 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001939 276.0
REGS1_k127_1306909_5 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000005828 228.0
REGS1_k127_1306909_6 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000008079 165.0
REGS1_k127_1306909_7 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000000003941 132.0
REGS1_k127_1306909_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000004552 126.0
REGS1_k127_1306909_9 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000008365 121.0
REGS1_k127_1308090_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 524.0
REGS1_k127_1308090_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 422.0
REGS1_k127_1308090_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 315.0
REGS1_k127_1308090_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001666 244.0
REGS1_k127_1308090_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
REGS1_k127_1308090_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000004479 180.0
REGS1_k127_1308090_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000008872 175.0
REGS1_k127_1308090_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000006862 146.0
REGS1_k127_1308090_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000007053 138.0
REGS1_k127_1316259_0 Prokaryotic cytochrome b561 - - - 2.997e-258 817.0
REGS1_k127_1316259_1 Prokaryotic cytochrome b561 - - - 5.211e-246 777.0
REGS1_k127_1316259_10 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082 - 1.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 315.0
REGS1_k127_1316259_11 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
REGS1_k127_1316259_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
REGS1_k127_1316259_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
REGS1_k127_1316259_14 Domain of Unknown function (DUF542) K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
REGS1_k127_1316259_16 cyclic nucleotide binding K01420,K21556,K21562 - - 0.000000000000000000000000000000000000000000000000000000323 198.0
REGS1_k127_1316259_17 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000001415 189.0
REGS1_k127_1316259_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 627.0
REGS1_k127_1316259_3 Iron-sulfur cluster-binding domain - - - 9.755e-194 612.0
REGS1_k127_1316259_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 490.0
REGS1_k127_1316259_5 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 416.0
REGS1_k127_1316259_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 433.0
REGS1_k127_1316259_8 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 355.0
REGS1_k127_1316259_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 346.0
REGS1_k127_1328861_0 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 581.0
REGS1_k127_1328861_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 554.0
REGS1_k127_1328861_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 549.0
REGS1_k127_1328861_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 286.0
REGS1_k127_1328861_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004215 271.0
REGS1_k127_1328861_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002607 258.0
REGS1_k127_1328861_6 peroxiredoxin activity K01607,K03469 - 3.1.26.4,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000001099 209.0
REGS1_k127_1328861_7 Cupin domain - - - 0.00000000000000000000000000000000003495 149.0
REGS1_k127_1328861_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000004372 119.0
REGS1_k127_1331414_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.33e-249 813.0
REGS1_k127_1331414_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 1.368e-209 658.0
REGS1_k127_1331414_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 474.0
REGS1_k127_1331414_3 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 476.0
REGS1_k127_1331414_4 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 354.0
REGS1_k127_1331414_5 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 325.0
REGS1_k127_1331414_6 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000003548 104.0
REGS1_k127_1339891_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 384.0
REGS1_k127_1342094_0 Peptidase family M1 domain - - - 1.183e-264 842.0
REGS1_k127_1342094_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 515.0
REGS1_k127_1342094_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 426.0
REGS1_k127_1342094_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000006522 218.0
REGS1_k127_1342094_4 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000001914 216.0
REGS1_k127_1342094_5 - - - - 0.0000000000000000000000000000000000037 139.0
REGS1_k127_1342094_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000018 76.0
REGS1_k127_1347910_0 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 313.0
REGS1_k127_1347910_1 PFAM Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 300.0
REGS1_k127_1347910_2 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000343 254.0
REGS1_k127_1347910_3 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000005568 149.0
REGS1_k127_1347910_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000002161 143.0
REGS1_k127_1347910_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000002473 114.0
REGS1_k127_1347910_6 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.0000002969 55.0
REGS1_k127_1361908_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 394.0
REGS1_k127_1361908_1 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000001074 217.0
REGS1_k127_1361908_2 IMP dehydrogenase activity - - - 0.000000000000000000000000000000002875 133.0
REGS1_k127_1416248_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 478.0
REGS1_k127_1416248_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 466.0
REGS1_k127_1416248_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003653 249.0
REGS1_k127_1416248_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000009133 235.0
REGS1_k127_1416248_4 Amidohydrolase family - - - 0.00000000000000000000000002904 113.0
REGS1_k127_1442339_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1476.0
REGS1_k127_1442339_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 6.024e-315 975.0
REGS1_k127_1442339_10 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 505.0
REGS1_k127_1442339_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 447.0
REGS1_k127_1442339_12 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 441.0
REGS1_k127_1442339_13 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 359.0
REGS1_k127_1442339_14 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 327.0
REGS1_k127_1442339_15 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 311.0
REGS1_k127_1442339_16 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
REGS1_k127_1442339_17 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007029 256.0
REGS1_k127_1442339_18 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000002425 198.0
REGS1_k127_1442339_19 - - - - 0.00000000000000000000000000000000000000000000000000001045 192.0
REGS1_k127_1442339_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.49e-304 944.0
REGS1_k127_1442339_21 - - - - 0.0000000000000000000000001585 107.0
REGS1_k127_1442339_22 PFAM purine or other phosphorylase family 1 - - - 0.0004635 51.0
REGS1_k127_1442339_3 May be involved in recombinational repair of damaged DNA K03631 - - 7.997e-239 750.0
REGS1_k127_1442339_4 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 7.199e-204 646.0
REGS1_k127_1442339_5 WD40-like Beta Propeller K03641 - - 5.802e-201 636.0
REGS1_k127_1442339_6 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 616.0
REGS1_k127_1442339_7 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 581.0
REGS1_k127_1442339_8 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 560.0
REGS1_k127_1442339_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 512.0
REGS1_k127_1480828_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1574.0
REGS1_k127_1480828_1 Voltage gated chloride channel K03281 - - 9.939e-207 665.0
REGS1_k127_1480828_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001516 195.0
REGS1_k127_1480828_11 - - - - 0.00000000000000000000000000000000001441 149.0
REGS1_k127_1480828_12 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000005165 145.0
REGS1_k127_1480828_13 - - - - 0.0000000000000000000006314 106.0
REGS1_k127_1480828_14 - - - - 0.00000000000000000001339 92.0
REGS1_k127_1480828_15 SnoaL-like domain - - - 0.000000000000006979 80.0
REGS1_k127_1480828_18 Diguanylate cyclase - - - 0.00000008729 63.0
REGS1_k127_1480828_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 522.0
REGS1_k127_1480828_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
REGS1_k127_1480828_4 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 381.0
REGS1_k127_1480828_5 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 377.0
REGS1_k127_1480828_6 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 314.0
REGS1_k127_1480828_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
REGS1_k127_1480828_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003129 244.0
REGS1_k127_1480828_9 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000000000945 192.0
REGS1_k127_1516144_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000003727 203.0
REGS1_k127_1516144_1 Frataxin-like domain K06202 - - 0.00000000000000000000000001106 109.0
REGS1_k127_1516144_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000008478 87.0
REGS1_k127_1552326_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 312.0
REGS1_k127_1552326_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000001799 112.0
REGS1_k127_1559040_0 radical SAM domain protein K22318 - - 4.056e-253 794.0
REGS1_k127_1559040_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 577.0
REGS1_k127_1559040_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 484.0
REGS1_k127_1559040_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 477.0
REGS1_k127_1564608_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
REGS1_k127_1564608_1 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000000000000000000004894 201.0
REGS1_k127_1564608_2 - - - - 0.00000000000000000000000000000000000000000238 159.0
REGS1_k127_157574_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.757e-245 764.0
REGS1_k127_157574_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 346.0
REGS1_k127_157574_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000004803 124.0
REGS1_k127_157574_11 Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000824 126.0
REGS1_k127_157574_12 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000002832 120.0
REGS1_k127_157574_13 TIGRFAM TonB K03832 - - 0.0000000000000000000001028 108.0
REGS1_k127_157574_14 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000414 70.0
REGS1_k127_157574_15 DoxX K16937 - 1.8.5.2 0.000000002804 66.0
REGS1_k127_157574_16 - - - - 0.0005401 43.0
REGS1_k127_157574_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 309.0
REGS1_k127_157574_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009878 277.0
REGS1_k127_157574_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001686 268.0
REGS1_k127_157574_5 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002631 259.0
REGS1_k127_157574_6 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000006539 197.0
REGS1_k127_157574_7 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000005449 175.0
REGS1_k127_157574_8 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000001742 170.0
REGS1_k127_157574_9 - - - - 0.00000000000000000000000000000000000000004963 156.0
REGS1_k127_1601294_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 579.0
REGS1_k127_1601294_1 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 341.0
REGS1_k127_1601294_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
REGS1_k127_1601294_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001216 166.0
REGS1_k127_1601294_4 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000001562 126.0
REGS1_k127_1601294_5 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.000000000000000000005131 94.0
REGS1_k127_1696958_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
REGS1_k127_1696958_1 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 338.0
REGS1_k127_1696958_2 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 327.0
REGS1_k127_1696958_3 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 298.0
REGS1_k127_1696958_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000001156 218.0
REGS1_k127_1696958_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000008222 198.0
REGS1_k127_1696958_6 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000001863 163.0
REGS1_k127_1696958_7 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000002997 139.0
REGS1_k127_1696958_8 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0019344,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.80,2.8.1.11 0.00000189 50.0
REGS1_k127_1702510_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000001686 214.0
REGS1_k127_1702510_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000001021 87.0
REGS1_k127_1733052_0 Flotillin K07192 - - 9.438e-212 667.0
REGS1_k127_1733052_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 333.0
REGS1_k127_1733052_2 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009133 269.0
REGS1_k127_1733052_3 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000007651 197.0
REGS1_k127_1733052_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000000000000000000000002947 171.0
REGS1_k127_1733052_5 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000001064 149.0
REGS1_k127_1733052_6 methyltransferase activity - - - 0.000000000000000000000000000000008038 137.0
REGS1_k127_1733052_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000005853 78.0
REGS1_k127_1737129_0 Amidohydrolase family - - - 2.188e-198 634.0
REGS1_k127_1737129_1 Peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 447.0
REGS1_k127_1748273_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 2.273e-251 796.0
REGS1_k127_1748273_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 554.0
REGS1_k127_1748273_2 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 506.0
REGS1_k127_1748273_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 429.0
REGS1_k127_1748273_4 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000004117 197.0
REGS1_k127_1748273_5 ASPIC and UnbV - - - 0.00000000000000002665 94.0
REGS1_k127_1748273_6 Redoxin domain protein - - - 0.0000000000000001546 91.0
REGS1_k127_175792_0 Glycosyl transferase, family 2 - - - 0.0 1461.0
REGS1_k127_175792_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.761e-222 694.0
REGS1_k127_175792_10 - - - - 0.00000000000000000000000000000000000000000000000000000001205 200.0
REGS1_k127_175792_11 - - - - 0.000000000000000000000000000000001666 134.0
REGS1_k127_175792_13 histone H2A K63-linked ubiquitination - - - 0.00000000006109 64.0
REGS1_k127_175792_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 557.0
REGS1_k127_175792_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 472.0
REGS1_k127_175792_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 464.0
REGS1_k127_175792_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 375.0
REGS1_k127_175792_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 351.0
REGS1_k127_175792_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
REGS1_k127_175792_8 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000008488 224.0
REGS1_k127_175792_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000009047 207.0
REGS1_k127_1772320_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.886e-268 831.0
REGS1_k127_1772320_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 543.0
REGS1_k127_1772320_10 Glycosyl transferase, family 2 - - - 0.0000001728 54.0
REGS1_k127_1772320_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 462.0
REGS1_k127_1772320_3 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 370.0
REGS1_k127_1772320_4 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 305.0
REGS1_k127_1772320_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000223 178.0
REGS1_k127_1772320_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000005564 158.0
REGS1_k127_1772320_7 Belongs to the ATPase B chain family K02109 - - 0.0000000000000000000000000000000001913 137.0
REGS1_k127_1772320_8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000007746 127.0
REGS1_k127_1772320_9 Domain of unknown function (DUF309) - - - 0.000000000000000005371 88.0
REGS1_k127_1802636_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.734e-268 854.0
REGS1_k127_1802636_1 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 338.0
REGS1_k127_1802636_2 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000003435 259.0
REGS1_k127_1802636_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000000000000002089 177.0
REGS1_k127_1802636_4 dUTPase K01494 - 3.5.4.13 0.00000000788 59.0
REGS1_k127_1813972_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 416.0
REGS1_k127_1949840_0 HD domain - - - 2.715e-237 754.0
REGS1_k127_1949840_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 403.0
REGS1_k127_196017_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.432e-314 979.0
REGS1_k127_196017_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 497.0
REGS1_k127_196017_2 ABC transporter, transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 463.0
REGS1_k127_196017_3 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000001326 214.0
REGS1_k127_198899_0 Amidohydrolase family - - - 9.018e-215 682.0
REGS1_k127_198899_1 Peptidase, M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
REGS1_k127_2119223_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.071e-209 660.0
REGS1_k127_2119223_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 8.905e-208 653.0
REGS1_k127_2119223_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 542.0
REGS1_k127_2119223_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000004165 208.0
REGS1_k127_2119223_4 Protein of unknown function (DUF2393) - - - 0.0000000000000000000000000000000000000003291 154.0
REGS1_k127_2119223_5 Amino acid permease - - - 0.0000000000000000000000000000000000008686 141.0
REGS1_k127_2159077_0 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 3.017e-239 751.0
REGS1_k127_2159077_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000003287 213.0
REGS1_k127_2277155_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 553.0
REGS1_k127_2277155_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 559.0
REGS1_k127_2277155_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 520.0
REGS1_k127_2277155_3 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 439.0
REGS1_k127_2277155_4 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 369.0
REGS1_k127_2277155_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000007604 193.0
REGS1_k127_2277155_6 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000000246 166.0
REGS1_k127_2277155_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000001637 160.0
REGS1_k127_2277155_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000005959 87.0
REGS1_k127_2277155_9 - - - - 0.00000000008566 67.0
REGS1_k127_230789_0 - - - - 0.000000000000000000000000000000007786 136.0
REGS1_k127_230789_2 signal transduction histidine kinase - - - 0.00007083 53.0
REGS1_k127_2316505_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 452.0
REGS1_k127_2316505_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000007209 250.0
REGS1_k127_2335544_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 385.0
REGS1_k127_2335544_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 314.0
REGS1_k127_2335544_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 281.0
REGS1_k127_2335544_3 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000001047 176.0
REGS1_k127_2359611_0 GlcNAc-PI de-N-acetylase K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 297.0
REGS1_k127_2359611_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 285.0
REGS1_k127_2359611_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
REGS1_k127_2359611_3 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000000000003004 157.0
REGS1_k127_2359611_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000002632 114.0
REGS1_k127_2364395_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 447.0
REGS1_k127_2364395_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 379.0
REGS1_k127_237597_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 9.53e-237 749.0
REGS1_k127_237597_1 FMN binding - - - 8.164e-224 709.0
REGS1_k127_237597_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001298 252.0
REGS1_k127_237597_3 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000002634 173.0
REGS1_k127_237597_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000002672 154.0
REGS1_k127_2401315_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 392.0
REGS1_k127_2401315_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
REGS1_k127_2423695_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 546.0
REGS1_k127_2423695_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 350.0
REGS1_k127_2423695_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 312.0
REGS1_k127_2423695_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000001171 125.0
REGS1_k127_2423695_4 sh3 domain protein - - - 0.00000001484 57.0
REGS1_k127_2428629_0 Trypsin K04771 - 3.4.21.107 3.048e-213 674.0
REGS1_k127_2428629_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 375.0
REGS1_k127_2428629_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 362.0
REGS1_k127_2428629_3 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 376.0
REGS1_k127_2428629_4 NACHT domain - - - 0.0000000000000000000000000000001162 141.0
REGS1_k127_2428629_5 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000003794 118.0
REGS1_k127_2428629_6 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000002147 69.0
REGS1_k127_2428629_7 SAM domain (Sterile alpha motif) - - - 0.000001837 61.0
REGS1_k127_2443680_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.587e-200 635.0
REGS1_k127_2443680_1 - - - - 0.000000000000000000000000000000000000000002592 162.0
REGS1_k127_2457493_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 9.087e-197 626.0
REGS1_k127_2457493_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 513.0
REGS1_k127_2457493_2 Gas vesicle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 339.0
REGS1_k127_2457493_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000003538 207.0
REGS1_k127_2457493_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000002573 158.0
REGS1_k127_2457493_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000005453 154.0
REGS1_k127_2463143_0 Tricorn protease homolog K08676 - - 3.507e-295 945.0
REGS1_k127_2463143_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 2.143e-224 707.0
REGS1_k127_2463143_10 PAS sensor protein - - - 0.000000000000000000000000000000000000000000006975 170.0
REGS1_k127_2463143_11 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000002815 170.0
REGS1_k127_2463143_13 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000000002389 153.0
REGS1_k127_2463143_14 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000005417 148.0
REGS1_k127_2463143_15 - - - - 0.000000000000000000000000000001446 128.0
REGS1_k127_2463143_16 Alpha/beta hydrolase family - - - 0.00000000000000000000007211 109.0
REGS1_k127_2463143_17 - - - - 0.000000000003121 71.0
REGS1_k127_2463143_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 6.397e-197 629.0
REGS1_k127_2463143_3 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 530.0
REGS1_k127_2463143_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 421.0
REGS1_k127_2463143_5 peptidase M36 K01417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 380.0
REGS1_k127_2463143_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001132 260.0
REGS1_k127_2463143_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000002624 269.0
REGS1_k127_2463143_8 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000000000002799 193.0
REGS1_k127_2463143_9 cellulose binding - - - 0.00000000000000000000000000000000000000000000000005975 205.0
REGS1_k127_2468829_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 477.0
REGS1_k127_2468829_1 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 313.0
REGS1_k127_2468829_2 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 288.0
REGS1_k127_2468829_3 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000002172 132.0
REGS1_k127_2468829_4 Recombinase zinc beta ribbon domain - - - 0.000003172 49.0
REGS1_k127_248930_0 Protein kinase domain K12132 - 2.7.11.1 1.879e-219 707.0
REGS1_k127_248930_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000007301 104.0
REGS1_k127_248930_2 - - - - 0.000000000000000000002058 98.0
REGS1_k127_250758_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1236.0
REGS1_k127_250758_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 6.769e-241 752.0
REGS1_k127_250758_10 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 339.0
REGS1_k127_250758_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 338.0
REGS1_k127_250758_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002577 297.0
REGS1_k127_250758_13 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 276.0
REGS1_k127_250758_14 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000001646 181.0
REGS1_k127_250758_15 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000003516 142.0
REGS1_k127_250758_16 acetyltransferase - - - 0.0000000000000000000000000000002482 128.0
REGS1_k127_250758_17 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000000000000006863 127.0
REGS1_k127_250758_18 Tfp pilus assembly protein FimV - - - 0.000000000000000000000001347 112.0
REGS1_k127_250758_2 Ami_3 K01448 - 3.5.1.28 1.734e-216 692.0
REGS1_k127_250758_20 - - - - 0.0000000000000002376 81.0
REGS1_k127_250758_3 von Willebrand factor (vWF) type A domain K07114 - - 1.969e-210 665.0
REGS1_k127_250758_4 Bacterial regulatory protein, Fis family K07713 - - 4.294e-210 662.0
REGS1_k127_250758_5 Two component regulator propeller - - - 1.686e-207 669.0
REGS1_k127_250758_6 Type II/IV secretion system protein K02669 - - 3.278e-199 623.0
REGS1_k127_250758_7 PFAM Type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 464.0
REGS1_k127_250758_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 405.0
REGS1_k127_250758_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 409.0
REGS1_k127_2508695_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 496.0
REGS1_k127_2508695_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 498.0
REGS1_k127_2508695_10 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000007655 185.0
REGS1_k127_2508695_11 Universal stress protein - - - 0.000000000000000000000000000000000000000000000007809 184.0
REGS1_k127_2508695_12 ATP-independent chaperone mediated protein folding - - - 0.00000000178 66.0
REGS1_k127_2508695_13 - - - - 0.00005027 53.0
REGS1_k127_2508695_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 380.0
REGS1_k127_2508695_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 372.0
REGS1_k127_2508695_4 Domain of unknown function (DUF4082) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 386.0
REGS1_k127_2508695_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 374.0
REGS1_k127_2508695_6 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 352.0
REGS1_k127_2508695_7 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005848 274.0
REGS1_k127_2508695_8 nitrite transmembrane transporter activity K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003367 254.0
REGS1_k127_2508695_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000007707 231.0
REGS1_k127_2520402_0 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 539.0
REGS1_k127_2520402_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 473.0
REGS1_k127_2520402_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 410.0
REGS1_k127_2520402_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 357.0
REGS1_k127_2520402_4 - K07018 - - 0.0000000000000000000000000000000000000000000003277 169.0
REGS1_k127_2566620_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 321.0
REGS1_k127_2566620_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 323.0
REGS1_k127_2566620_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000001358 78.0
REGS1_k127_2567098_0 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 451.0
REGS1_k127_2567098_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000001674 60.0
REGS1_k127_2571959_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 475.0
REGS1_k127_2571959_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 417.0
REGS1_k127_2571959_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000001632 70.0
REGS1_k127_2573755_0 Malate synthase K01638 - 2.3.3.9 0.0 1200.0
REGS1_k127_2573755_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.593e-289 903.0
REGS1_k127_2573755_10 synthetase, class II (G H P K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 590.0
REGS1_k127_2573755_11 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 582.0
REGS1_k127_2573755_12 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 575.0
REGS1_k127_2573755_13 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 554.0
REGS1_k127_2573755_15 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 509.0
REGS1_k127_2573755_16 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 486.0
REGS1_k127_2573755_17 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 469.0
REGS1_k127_2573755_18 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 412.0
REGS1_k127_2573755_19 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
REGS1_k127_2573755_2 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 8.579e-284 883.0
REGS1_k127_2573755_20 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 356.0
REGS1_k127_2573755_21 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 306.0
REGS1_k127_2573755_22 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 303.0
REGS1_k127_2573755_23 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 297.0
REGS1_k127_2573755_24 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 288.0
REGS1_k127_2573755_25 Histidine kinase K01768,K02482,K07315,K20977 - 2.7.13.3,3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007853 287.0
REGS1_k127_2573755_26 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001228 278.0
REGS1_k127_2573755_27 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007444 286.0
REGS1_k127_2573755_28 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002927 252.0
REGS1_k127_2573755_29 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
REGS1_k127_2573755_3 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 7.828e-275 867.0
REGS1_k127_2573755_30 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000001901 194.0
REGS1_k127_2573755_31 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000000000000000001324 201.0
REGS1_k127_2573755_32 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000006243 185.0
REGS1_k127_2573755_33 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001317 188.0
REGS1_k127_2573755_34 - - - - 0.0000000000000000000000000000000000000000000000003365 191.0
REGS1_k127_2573755_35 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000001166 179.0
REGS1_k127_2573755_36 Thioesterase - - - 0.000000000000000000000000000000000000000509 152.0
REGS1_k127_2573755_37 PIN domain - - - 0.0000000000000000000000000000000000007118 146.0
REGS1_k127_2573755_38 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000001635 140.0
REGS1_k127_2573755_39 Transposase K07491 - - 0.00000000000000000000000000000000007861 137.0
REGS1_k127_2573755_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.71e-255 800.0
REGS1_k127_2573755_40 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000000000001616 124.0
REGS1_k127_2573755_41 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000006556 108.0
REGS1_k127_2573755_42 Helix-turn-helix domain - - - 0.00000000000000000000000006617 119.0
REGS1_k127_2573755_43 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000001675 113.0
REGS1_k127_2573755_44 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000004215 110.0
REGS1_k127_2573755_45 PilZ domain - - - 0.0000000000000000000000005133 107.0
REGS1_k127_2573755_46 - - - - 0.000000000000000000000006762 113.0
REGS1_k127_2573755_47 23S rRNA-intervening sequence protein - - - 0.000000000000000115 82.0
REGS1_k127_2573755_48 - - - - 0.000000000000009548 79.0
REGS1_k127_2573755_49 Recombinase zinc beta ribbon domain K06400 - - 0.0000000001366 65.0
REGS1_k127_2573755_5 Putative modulator of DNA gyrase K03568 - - 2.681e-248 775.0
REGS1_k127_2573755_50 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000005767 57.0
REGS1_k127_2573755_51 PD-(D/E)XK endonuclease - - - 0.000001224 58.0
REGS1_k127_2573755_52 SnoaL-like domain - - - 0.000001621 58.0
REGS1_k127_2573755_53 Flagellar hook protein flgE - - - 0.0003446 50.0
REGS1_k127_2573755_54 23S rRNA-intervening sequence protein - - - 0.0004362 43.0
REGS1_k127_2573755_6 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.061e-236 736.0
REGS1_k127_2573755_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.261e-221 691.0
REGS1_k127_2573755_8 Isocitrate lyase family K01637 - 4.1.3.1 3.831e-214 672.0
REGS1_k127_2573755_9 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 5.599e-206 652.0
REGS1_k127_260368_0 Histidine kinase K02482 - 2.7.13.3 2.73e-290 929.0
REGS1_k127_260368_1 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000555 168.0
REGS1_k127_260368_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000001254 135.0
REGS1_k127_2604667_0 S-adenosylhomocysteine deaminase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009853 247.0
REGS1_k127_2604667_1 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.000000000000000000000000000000000000000000000000000000000002488 218.0
REGS1_k127_2604667_2 xanthine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000006709 181.0
REGS1_k127_2611205_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 6.249e-214 676.0
REGS1_k127_2611205_1 Amidohydrolase family - - - 6.874e-198 626.0
REGS1_k127_2611205_10 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000004148 136.0
REGS1_k127_2611205_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000004807 120.0
REGS1_k127_2611205_12 - - - - 0.0000000000000000000000001516 111.0
REGS1_k127_2611205_14 deacetylase K22278 - 3.5.1.104 0.0000000000000000004638 96.0
REGS1_k127_2611205_15 Plasmid stabilization system - - - 0.0000000000000008793 80.0
REGS1_k127_2611205_16 negative regulation of transcription, DNA-templated - - - 0.00000000000004825 76.0
REGS1_k127_2611205_17 - - - - 0.0000000000006878 70.0
REGS1_k127_2611205_18 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000009551 72.0
REGS1_k127_2611205_19 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.00000000003757 67.0
REGS1_k127_2611205_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 539.0
REGS1_k127_2611205_20 Protein of unknown function (DUF3891) - - - 0.0000000000378 73.0
REGS1_k127_2611205_3 Nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 507.0
REGS1_k127_2611205_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 495.0
REGS1_k127_2611205_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 311.0
REGS1_k127_2611205_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004744 254.0
REGS1_k127_2611205_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
REGS1_k127_2611205_8 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000000003619 189.0
REGS1_k127_2611205_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000001726 160.0
REGS1_k127_2620551_0 AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 508.0
REGS1_k127_2620551_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 342.0
REGS1_k127_2620551_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 278.0
REGS1_k127_265143_0 TOBE domain K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 329.0
REGS1_k127_265143_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 309.0
REGS1_k127_265143_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 290.0
REGS1_k127_265143_3 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004701 284.0
REGS1_k127_265143_4 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000005375 235.0
REGS1_k127_265143_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000963 214.0
REGS1_k127_265143_6 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000008542 150.0
REGS1_k127_265143_7 - - - - 0.0000000000000000000497 96.0
REGS1_k127_2651465_0 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 323.0
REGS1_k127_2651465_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 242.0
REGS1_k127_2651465_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
REGS1_k127_2669807_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 331.0
REGS1_k127_2669807_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000008162 261.0
REGS1_k127_2669807_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
REGS1_k127_2669807_3 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.000000000000000000000000003586 129.0
REGS1_k127_2669807_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000001087 105.0
REGS1_k127_2669807_5 - - - - 0.0000000000000000000002736 107.0
REGS1_k127_2669807_6 sequence-specific DNA binding - - - 0.000003465 57.0
REGS1_k127_2669807_7 Uncharacterised nucleotidyltransferase - - - 0.00003974 51.0
REGS1_k127_2669807_9 FG-GAP repeat - - - 0.0004575 53.0
REGS1_k127_2684268_0 PFAM Iron permease FTR1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 330.0
REGS1_k127_2684268_1 ABC transporter permease - - - 0.00003749 48.0
REGS1_k127_2686056_0 Belongs to the BshC family K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 490.0
REGS1_k127_2686056_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 451.0
REGS1_k127_2686056_2 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 399.0
REGS1_k127_2686056_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 372.0
REGS1_k127_2686056_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001898 214.0
REGS1_k127_2696408_0 Aldehyde dehydrogenase family K22445 - 1.2.99.10 7.213e-196 623.0
REGS1_k127_2696408_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 601.0
REGS1_k127_2696408_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 483.0
REGS1_k127_2696408_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 445.0
REGS1_k127_2696408_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 312.0
REGS1_k127_2696408_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 302.0
REGS1_k127_2696408_6 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007786 282.0
REGS1_k127_2696408_7 Peptidase, M20 - - - 0.000000000000000000000002609 106.0
REGS1_k127_2696408_8 - - - - 0.00000000000000000007335 93.0
REGS1_k127_2698896_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 1.71e-272 853.0
REGS1_k127_2698896_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0000000000000000000000003116 108.0
REGS1_k127_2698896_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.000000000000000000000002083 105.0
REGS1_k127_272156_0 Peptidase family M1 domain - - - 3.285e-212 689.0
REGS1_k127_272156_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 457.0
REGS1_k127_272156_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 440.0
REGS1_k127_272156_3 Protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 380.0
REGS1_k127_272156_4 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 330.0
REGS1_k127_272156_5 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001642 239.0
REGS1_k127_272156_6 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000000000002017 203.0
REGS1_k127_272156_7 Regulatory protein - - - 0.000000000000000000000000000000000000000000000000006021 184.0
REGS1_k127_272156_8 - - - - 0.00000000000000000000000000000000000002744 150.0
REGS1_k127_2722623_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.746e-236 735.0
REGS1_k127_2722623_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 392.0
REGS1_k127_2722623_2 PFAM Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 364.0
REGS1_k127_2722623_3 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 316.0
REGS1_k127_2722623_4 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 299.0
REGS1_k127_2722623_5 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 284.0
REGS1_k127_2722623_6 PFAM Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005313 246.0
REGS1_k127_2722623_9 Domain of unknown function (DUF4440) - - - 0.000003065 58.0
REGS1_k127_2748302_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 344.0
REGS1_k127_2748302_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
REGS1_k127_2748302_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000003561 205.0
REGS1_k127_2748302_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000005612 183.0
REGS1_k127_2748302_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000003358 129.0
REGS1_k127_2748302_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000003599 101.0
REGS1_k127_2757675_0 PFAM Transposase, IS801 IS1294 - - - 1.428e-204 641.0
REGS1_k127_277072_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 3.202e-261 812.0
REGS1_k127_277072_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.476e-205 648.0
REGS1_k127_277072_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 573.0
REGS1_k127_277072_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 472.0
REGS1_k127_277072_4 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 473.0
REGS1_k127_277072_5 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
REGS1_k127_277072_6 - - - - 0.00000000001258 67.0
REGS1_k127_282938_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.105e-208 666.0
REGS1_k127_282938_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 496.0
REGS1_k127_282938_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 384.0
REGS1_k127_282938_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 336.0
REGS1_k127_282938_4 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 317.0
REGS1_k127_282938_5 TonB C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 264.0
REGS1_k127_282938_6 - - - - 0.0000000000000000000000000000000000009176 147.0
REGS1_k127_282938_7 - - - - 0.0000006078 61.0
REGS1_k127_2855523_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 7.383e-222 700.0
REGS1_k127_2855523_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 580.0
REGS1_k127_2855523_10 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000000001116 209.0
REGS1_k127_2855523_11 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000000001028 187.0
REGS1_k127_2855523_12 Preprotein translocase, YajC K03210 - - 0.000000000000000000000000121 110.0
REGS1_k127_2855523_13 - - - - 0.0000000000000002842 82.0
REGS1_k127_2855523_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 533.0
REGS1_k127_2855523_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 510.0
REGS1_k127_2855523_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 387.0
REGS1_k127_2855523_5 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 379.0
REGS1_k127_2855523_6 TIGRFAM TonB K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 335.0
REGS1_k127_2855523_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 325.0
REGS1_k127_2855523_8 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 290.0
REGS1_k127_2855523_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000000000001091 222.0
REGS1_k127_2896199_0 PFAM Prolyl oligopeptidase family - - - 4.457e-213 680.0
REGS1_k127_2896199_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 389.0
REGS1_k127_2896199_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000009905 208.0
REGS1_k127_2896199_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000004462 171.0
REGS1_k127_2896199_4 Bacterial DNA-binding protein K03530 - - 0.000000000000000000000000000000000000000002067 156.0
REGS1_k127_2896199_5 - - - - 0.0000000000000000000000000000000001132 141.0
REGS1_k127_2896199_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000001341 97.0
REGS1_k127_2896199_7 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000135 91.0
REGS1_k127_290643_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 512.0
REGS1_k127_290643_1 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000000000000002976 156.0
REGS1_k127_290643_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000005953 66.0
REGS1_k127_2914725_0 Sortilin, neurotensin receptor 3, - - - 0.0 1212.0
REGS1_k127_2914725_1 ATPase BadF BadG BcrA BcrD type - - - 1.477e-321 1013.0
REGS1_k127_2914725_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 506.0
REGS1_k127_2914725_3 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 394.0
REGS1_k127_2914725_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000005506 141.0
REGS1_k127_2914725_5 - - - - 0.00000000000000000000000000005714 120.0
REGS1_k127_2923234_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 331.0
REGS1_k127_2923234_1 PFAM peptidase K16922 - - 0.00000000000000000000000000000000000000000000005264 192.0
REGS1_k127_2923234_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000001325 171.0
REGS1_k127_2923234_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000000000005768 164.0
REGS1_k127_2923234_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000001111 93.0
REGS1_k127_2923234_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000001017 76.0
REGS1_k127_294543_0 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 452.0
REGS1_k127_294543_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000004248 148.0
REGS1_k127_2951168_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 376.0
REGS1_k127_2951168_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000908 223.0
REGS1_k127_2955567_0 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000001532 222.0
REGS1_k127_2955567_1 - - - - 0.00000000000000000000000000000002584 128.0
REGS1_k127_2955567_2 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000001068 124.0
REGS1_k127_2955567_3 Pilus assembly protein K02662 - - 0.000000000000000000000000000002607 127.0
REGS1_k127_2955567_4 - - - - 0.00000000000000000000000000002173 126.0
REGS1_k127_2955567_5 - K02664 - - 0.000000000000000000508 94.0
REGS1_k127_3034024_0 citrate CoA-transferase activity K01643 - 2.8.3.10 1.231e-269 837.0
REGS1_k127_3156046_0 Elongation factor G, domain IV K02355 - - 0.0 1077.0
REGS1_k127_3156046_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 515.0
REGS1_k127_3156046_2 Pfam:N_methyl_2 - - - 0.000000000000000000000000000000001183 138.0
REGS1_k127_3168211_0 ATPase BadF BadG BcrA BcrD type - - - 4.97e-239 758.0
REGS1_k127_3174667_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.286e-235 735.0
REGS1_k127_3174667_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.94e-231 727.0
REGS1_k127_3174667_2 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 329.0
REGS1_k127_3174667_3 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000009112 215.0
REGS1_k127_3174667_4 Glutathione peroxidase K02199 - - 0.0000000000000000000000000000000000000000000000000000000002302 208.0
REGS1_k127_3174667_5 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000000000004095 166.0
REGS1_k127_3174667_6 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000003806 150.0
REGS1_k127_3174667_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000006413 110.0
REGS1_k127_318467_0 ASPIC and UnbV - - - 6.454e-197 621.0
REGS1_k127_318467_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 454.0
REGS1_k127_318467_2 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 349.0
REGS1_k127_318467_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000007754 62.0
REGS1_k127_320661_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 307.0
REGS1_k127_321868_0 amino acid transport K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 582.0
REGS1_k127_321868_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 398.0
REGS1_k127_3218813_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.702e-239 750.0
REGS1_k127_3218813_1 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000007221 222.0
REGS1_k127_3218813_3 - - - - 0.000000000000000000000007071 113.0
REGS1_k127_3268600_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 399.0
REGS1_k127_3268600_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 329.0
REGS1_k127_3268600_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 336.0
REGS1_k127_3268600_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002416 239.0
REGS1_k127_3268600_4 - - - - 0.0000000000000000000000000000000000000000000000000000000006424 214.0
REGS1_k127_3268600_5 - - - - 0.0000000000003074 74.0
REGS1_k127_331313_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.54e-231 726.0
REGS1_k127_331313_1 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000000000000000001853 221.0
REGS1_k127_3475804_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 392.0
REGS1_k127_3475804_1 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000001836 134.0
REGS1_k127_3482244_0 Seven times multi-haem cytochrome CxxCH - - - 4.248e-198 626.0
REGS1_k127_3482244_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 311.0
REGS1_k127_3482244_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
REGS1_k127_3482244_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000006879 62.0
REGS1_k127_3493051_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 388.0
REGS1_k127_3493051_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 312.0
REGS1_k127_3493051_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003224 239.0
REGS1_k127_3493051_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000001433 236.0
REGS1_k127_3493051_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000004674 163.0
REGS1_k127_3493051_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000002839 162.0
REGS1_k127_3493051_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000006633 116.0
REGS1_k127_3493051_7 Ribosomal protein L33 K02913 - - 0.0000000000000000000002238 96.0
REGS1_k127_3494530_0 diguanylate cyclase K02030,K06950,K16923 - - 0.0 1200.0
REGS1_k127_3494530_1 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 532.0
REGS1_k127_3494530_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
REGS1_k127_3494530_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000004022 222.0
REGS1_k127_3494530_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000003447 222.0
REGS1_k127_3494530_5 - - - - 0.00000000000000000000000000001488 126.0
REGS1_k127_3494530_6 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000002885 81.0
REGS1_k127_3513652_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1478.0
REGS1_k127_3513652_1 PFAM Iron permease FTR1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 567.0
REGS1_k127_3513652_10 - - - - 0.00002534 52.0
REGS1_k127_3513652_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 557.0
REGS1_k127_3513652_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 405.0
REGS1_k127_3513652_4 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
REGS1_k127_3513652_5 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 296.0
REGS1_k127_3513652_6 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000004469 252.0
REGS1_k127_3513652_7 - - - - 0.000000000000000000000000000000000002084 148.0
REGS1_k127_3513652_8 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000002471 123.0
REGS1_k127_3517094_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 541.0
REGS1_k127_3517094_1 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 503.0
REGS1_k127_351838_0 Amino acid permease - - - 1.04e-217 687.0
REGS1_k127_351838_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 393.0
REGS1_k127_351838_2 pfam rdd - - - 0.000000000000000000000000000000006238 132.0
REGS1_k127_351838_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000006032 54.0
REGS1_k127_3520716_0 HD domain - - - 1.827e-240 760.0
REGS1_k127_3520716_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 532.0
REGS1_k127_3520716_10 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000003717 114.0
REGS1_k127_3520716_12 SnoaL-like polyketide cyclase - - - 0.00001497 53.0
REGS1_k127_3520716_2 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 490.0
REGS1_k127_3520716_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 419.0
REGS1_k127_3520716_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 318.0
REGS1_k127_3520716_5 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 288.0
REGS1_k127_3520716_6 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000001551 195.0
REGS1_k127_3520716_7 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000001347 190.0
REGS1_k127_3520716_8 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000665 168.0
REGS1_k127_3520716_9 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000117 133.0
REGS1_k127_3527477_0 AAA ATPase K07478 - - 1.285e-218 686.0
REGS1_k127_3527477_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.482e-205 644.0
REGS1_k127_3527477_10 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000002107 139.0
REGS1_k127_3527477_11 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000002791 136.0
REGS1_k127_3527477_12 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000004117 142.0
REGS1_k127_3527477_13 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000004225 121.0
REGS1_k127_3527477_14 Protein of unknown function (DUF465) - - - 0.0000000000000000000005569 99.0
REGS1_k127_3527477_15 Putative cyclase - - - 0.0000000000000000003366 94.0
REGS1_k127_3527477_16 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000000008084 95.0
REGS1_k127_3527477_17 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000005945 49.0
REGS1_k127_3527477_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 453.0
REGS1_k127_3527477_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 351.0
REGS1_k127_3527477_4 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 290.0
REGS1_k127_3527477_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
REGS1_k127_3527477_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000008152 237.0
REGS1_k127_3527477_7 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001465 214.0
REGS1_k127_3527477_8 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000002714 221.0
REGS1_k127_3527477_9 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000001768 196.0
REGS1_k127_3541780_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.299e-198 624.0
REGS1_k127_3541780_1 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 546.0
REGS1_k127_3541780_10 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000002307 184.0
REGS1_k127_3541780_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000001236 183.0
REGS1_k127_3541780_12 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000001021 183.0
REGS1_k127_3541780_13 PFAM Chorismate mutase, type II - - - 0.00000000000000000000000000001575 120.0
REGS1_k127_3541780_14 Rieske (2fe-2S) K00499 - 1.14.15.7 0.00003359 47.0
REGS1_k127_3541780_3 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 494.0
REGS1_k127_3541780_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 467.0
REGS1_k127_3541780_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 388.0
REGS1_k127_3541780_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 337.0
REGS1_k127_3541780_7 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 306.0
REGS1_k127_3541780_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 303.0
REGS1_k127_3541780_9 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 279.0
REGS1_k127_3542453_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 306.0
REGS1_k127_3542453_1 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
REGS1_k127_3542453_2 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000001095 136.0
REGS1_k127_3543930_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 533.0
REGS1_k127_3543930_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 430.0
REGS1_k127_3543930_2 cheY-homologous receiver domain - - - 0.000000000000000000000009554 107.0
REGS1_k127_3543930_3 Metal cation transporter, zinc (Zn2 )-Iron (Fe2 ) permease (ZIP) family K07238 - - 0.00000000000001914 76.0
REGS1_k127_3544962_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 481.0
REGS1_k127_3544962_1 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005917 275.0
REGS1_k127_3544962_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000002374 162.0
REGS1_k127_355224_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 498.0
REGS1_k127_355224_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 428.0
REGS1_k127_355224_2 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 351.0
REGS1_k127_355224_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000003974 262.0
REGS1_k127_355224_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000006556 176.0
REGS1_k127_355224_5 Transposase IS200 like K07491 - - 0.000000000000000000000000001357 117.0
REGS1_k127_355224_6 phosphorelay signal transduction system - - - 0.000000000000000000000001338 112.0
REGS1_k127_355224_8 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000002829 80.0
REGS1_k127_3575315_0 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
REGS1_k127_3575315_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000002075 239.0
REGS1_k127_3575315_11 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000291 85.0
REGS1_k127_3575315_2 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
REGS1_k127_3575315_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000001452 204.0
REGS1_k127_3575315_4 methyltransferase activity K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464 2.1.1.197 0.0000000000000000000000000000000000000000000000000000003743 205.0
REGS1_k127_3575315_5 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000002028 169.0
REGS1_k127_3575315_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000003038 177.0
REGS1_k127_3575315_7 - - - - 0.0000000000000000000000000000000000000000001678 158.0
REGS1_k127_3575315_8 - - - - 0.0000000000000000000000000000000000000006469 149.0
REGS1_k127_3575315_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000001035 145.0
REGS1_k127_3582630_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 299.0
REGS1_k127_3582630_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000001151 177.0
REGS1_k127_3582630_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000001061 90.0
REGS1_k127_3594253_0 xanthine dehydrogenase activity K00087,K12528 - 1.17.1.4 2.763e-282 886.0
REGS1_k127_3594253_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 507.0
REGS1_k127_3594253_2 dihydroorotate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 444.0
REGS1_k127_3600054_0 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 495.0
REGS1_k127_3600054_1 - - - - 0.00000000000000001822 86.0
REGS1_k127_3605245_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 430.0
REGS1_k127_3605245_1 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 361.0
REGS1_k127_3605245_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
REGS1_k127_3605245_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
REGS1_k127_3605245_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000003489 267.0
REGS1_k127_3605245_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001414 206.0
REGS1_k127_3605245_6 membrane - - - 0.00000000000000000000000000000000000000002403 154.0
REGS1_k127_3605245_7 extracellular matrix structural constituent - - - 0.000000001777 67.0
REGS1_k127_3636181_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 7.393e-214 673.0
REGS1_k127_3636181_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 347.0
REGS1_k127_3636181_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000009968 198.0
REGS1_k127_3636181_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000007237 161.0
REGS1_k127_3641758_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.066e-229 717.0
REGS1_k127_3641758_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 551.0
REGS1_k127_3641758_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002766 278.0
REGS1_k127_3641758_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000002449 190.0
REGS1_k127_3646366_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1291.0
REGS1_k127_3646366_1 COG3209 Rhs family protein - - - 8.335e-283 889.0
REGS1_k127_3646366_2 SpoIVB peptidase S55 - - - 1.884e-268 838.0
REGS1_k127_3646366_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 579.0
REGS1_k127_3646366_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
REGS1_k127_3646366_5 cyclic nucleotide-binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
REGS1_k127_3646366_6 methyltransferase activity K00587 - 2.1.1.100 0.00000000000000000000000000000000000000000000000000001457 199.0
REGS1_k127_3646366_7 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000001777 190.0
REGS1_k127_3650338_0 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003974 269.0
REGS1_k127_3650338_1 - - - - 0.0000000000000000000000000000000000000000000000000000003649 203.0
REGS1_k127_3650338_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000183 181.0
REGS1_k127_3650338_3 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000005546 184.0
REGS1_k127_3650338_4 hemerythrin HHE cation binding domain - - - 0.000000000000001401 84.0
REGS1_k127_3650338_5 Fic/DOC family - - - 0.0000000005384 63.0
REGS1_k127_3652030_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 488.0
REGS1_k127_3652030_1 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 328.0
REGS1_k127_3652030_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000009545 122.0
REGS1_k127_3659990_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.455e-198 636.0
REGS1_k127_3659990_1 PFAM nitrite and sulphite reductase 4Fe-4S K00392 - 1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 337.0
REGS1_k127_3659990_2 R3H domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000003125 222.0
REGS1_k127_3659990_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000003122 123.0
REGS1_k127_3659990_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000007122 96.0
REGS1_k127_3659990_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000004768 90.0
REGS1_k127_369672_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.808e-261 810.0
REGS1_k127_369672_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 401.0
REGS1_k127_369672_2 Major Facilitator Superfamily - - - 0.0000000000000000000000001023 111.0
REGS1_k127_369672_3 PFAM VanZ - - - 0.0000000000000000003036 94.0
REGS1_k127_3727932_0 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 393.0
REGS1_k127_3727932_1 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 300.0
REGS1_k127_373755_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 408.0
REGS1_k127_373755_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
REGS1_k127_375053_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 498.0
REGS1_k127_375053_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000194 267.0
REGS1_k127_375053_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000569 265.0
REGS1_k127_375053_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000001458 194.0
REGS1_k127_375053_4 Outer membrane efflux protein - - - 0.0000001103 57.0
REGS1_k127_3773806_0 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 1843.0
REGS1_k127_3773806_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 2.097e-279 871.0
REGS1_k127_3773806_10 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000003143 222.0
REGS1_k127_3773806_11 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000001515 194.0
REGS1_k127_3773806_12 Zincin-like metallopeptidase - - - 0.000000000000000000005194 96.0
REGS1_k127_3773806_13 - - - - 0.00000000000000000001412 98.0
REGS1_k127_3773806_14 Domain of unknown function DUF302 - - - 0.0000000000000000001179 94.0
REGS1_k127_3773806_15 Cupin domain - - - 0.0000000000000000002618 93.0
REGS1_k127_3773806_16 - - - - 0.00000002444 65.0
REGS1_k127_3773806_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.74e-244 761.0
REGS1_k127_3773806_3 Dehydratase family K01687 - 4.2.1.9 1.813e-233 737.0
REGS1_k127_3773806_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 491.0
REGS1_k127_3773806_5 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 479.0
REGS1_k127_3773806_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 421.0
REGS1_k127_3773806_7 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 356.0
REGS1_k127_3773806_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 338.0
REGS1_k127_3773806_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000899 218.0
REGS1_k127_3827179_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0 1035.0
REGS1_k127_3827179_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.713e-269 838.0
REGS1_k127_3827179_10 - - - - 0.000000000000000000003788 97.0
REGS1_k127_3827179_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000008281 70.0
REGS1_k127_3827179_2 Proton-conducting membrane transporter K00343 - 1.6.5.3 4.142e-211 667.0
REGS1_k127_3827179_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002789 274.0
REGS1_k127_3827179_4 - - - - 0.0000000000000000000000000000000000000000000002661 175.0
REGS1_k127_3827179_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000006745 171.0
REGS1_k127_3827179_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000005512 161.0
REGS1_k127_3827179_7 - - - - 0.0000000000000000000000000000000000004285 146.0
REGS1_k127_3827179_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000003296 99.0
REGS1_k127_3848716_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 366.0
REGS1_k127_3848716_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000004528 134.0
REGS1_k127_3857826_0 Sigma factor PP2C-like phosphatases - - - 1.327e-198 627.0
REGS1_k127_3857826_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 327.0
REGS1_k127_3857826_2 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 310.0
REGS1_k127_3857826_3 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 303.0
REGS1_k127_3857826_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002948 276.0
REGS1_k127_3857826_5 - - - - 0.0000000000000000000000000000000000000000000000000007225 196.0
REGS1_k127_3857826_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000007694 134.0
REGS1_k127_3857826_8 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000004994 111.0
REGS1_k127_3857826_9 COG4980 Gas vesicle protein - - - 0.0008371 48.0
REGS1_k127_3887046_0 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 431.0
REGS1_k127_3887046_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 421.0
REGS1_k127_3887046_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 295.0
REGS1_k127_3887046_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000005594 63.0
REGS1_k127_3900673_0 B12 binding domain - - - 1.648e-253 790.0
REGS1_k127_3900673_1 B12 binding domain - - - 5.081e-196 626.0
REGS1_k127_3900673_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 457.0
REGS1_k127_3900673_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000002242 161.0
REGS1_k127_3900673_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000006553 169.0
REGS1_k127_3923356_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 399.0
REGS1_k127_3923356_1 - - - - 0.00000000000000000000000000000000000007571 149.0
REGS1_k127_3923356_2 - - - - 0.0000009166 57.0
REGS1_k127_3925933_0 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 474.0
REGS1_k127_3925933_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 441.0
REGS1_k127_3925933_10 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000001104 130.0
REGS1_k127_3925933_13 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779 - 2.5.1.77 0.0000000000000000000008152 99.0
REGS1_k127_3925933_14 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000004548 53.0
REGS1_k127_3925933_2 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 420.0
REGS1_k127_3925933_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 404.0
REGS1_k127_3925933_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 332.0
REGS1_k127_3925933_5 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 319.0
REGS1_k127_3925933_6 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
REGS1_k127_3925933_7 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
REGS1_k127_3925933_8 - - - - 0.00000000000000000000000000000000008922 142.0
REGS1_k127_3925933_9 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000008475 139.0
REGS1_k127_3944288_0 DegT/DnrJ/EryC1/StrS aminotransferase family K01740 - 2.5.1.49 6.47e-231 722.0
REGS1_k127_3944288_1 Lamin Tail Domain K07004 - - 4.319e-200 665.0
REGS1_k127_3944288_10 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000006104 121.0
REGS1_k127_3944288_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 592.0
REGS1_k127_3944288_3 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 433.0
REGS1_k127_3944288_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 428.0
REGS1_k127_3944288_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 365.0
REGS1_k127_3944288_6 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001836 273.0
REGS1_k127_3944288_7 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001657 234.0
REGS1_k127_3944288_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000005475 237.0
REGS1_k127_3944288_9 DinB family - - - 0.000000000000000000000000000000000000000000161 164.0
REGS1_k127_3967881_0 Peptidase M16 inactive domain K07263 - - 2.428e-245 782.0
REGS1_k127_3967881_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 559.0
REGS1_k127_3967881_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 493.0
REGS1_k127_3967881_3 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 332.0
REGS1_k127_3967881_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000002681 250.0
REGS1_k127_3967881_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000284 88.0
REGS1_k127_3974388_0 Protein of unknown function (DUF1800) - - - 1.309e-218 699.0
REGS1_k127_3974388_1 Tetratricopeptide repeat - - - 2.616e-217 688.0
REGS1_k127_3974388_10 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000003775 98.0
REGS1_k127_3974388_11 Domain of unknown function (DUF4412) - - - 0.000008002 56.0
REGS1_k127_3974388_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 602.0
REGS1_k127_3974388_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 496.0
REGS1_k127_3974388_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 435.0
REGS1_k127_3974388_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 414.0
REGS1_k127_3974388_6 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 336.0
REGS1_k127_3974388_7 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001876 256.0
REGS1_k127_3974388_8 BioY family K03523 - - 0.0000000000000000000000000000000000000000000004446 173.0
REGS1_k127_3994094_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 568.0
REGS1_k127_3994094_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 410.0
REGS1_k127_3994094_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000002141 255.0
REGS1_k127_3994094_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001623 226.0
REGS1_k127_3994094_4 Protein of unknown function with PCYCGC motif - - - 0.0000000000000000000000000000000000000000000001669 171.0
REGS1_k127_3994094_5 Doxx family - - - 0.0000000000000000000000000000000000003086 144.0
REGS1_k127_3994094_6 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.000000000000000000000000000000000005815 137.0
REGS1_k127_3994094_7 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000663 133.0
REGS1_k127_3994094_8 ARD/ARD' family - - - 0.0000000000000000000000000000002241 126.0
REGS1_k127_3994094_9 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000001963 51.0
REGS1_k127_4047527_0 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 403.0
REGS1_k127_4047527_1 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 363.0
REGS1_k127_4047527_2 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000007331 151.0
REGS1_k127_4047527_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000001073 140.0
REGS1_k127_4128144_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
REGS1_k127_4128144_1 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
REGS1_k127_4128144_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001099 236.0
REGS1_k127_4128144_4 Suf system fes assembly protein K04488 - - 0.000000000000000000503 89.0
REGS1_k127_4131991_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1246.0
REGS1_k127_4131991_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.112e-251 784.0
REGS1_k127_4131991_10 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 413.0
REGS1_k127_4131991_11 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 407.0
REGS1_k127_4131991_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 370.0
REGS1_k127_4131991_13 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 332.0
REGS1_k127_4131991_14 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
REGS1_k127_4131991_15 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
REGS1_k127_4131991_16 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000002735 189.0
REGS1_k127_4131991_17 DinB superfamily K07552 - - 0.00000000000000000000000000000000000000000008223 168.0
REGS1_k127_4131991_18 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000001551 172.0
REGS1_k127_4131991_2 Peptidase dimerisation domain - - - 3.919e-213 672.0
REGS1_k127_4131991_21 - - - - 0.00000003274 62.0
REGS1_k127_4131991_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 600.0
REGS1_k127_4131991_4 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 536.0
REGS1_k127_4131991_5 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 490.0
REGS1_k127_4131991_6 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 456.0
REGS1_k127_4131991_7 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 436.0
REGS1_k127_4131991_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 436.0
REGS1_k127_4131991_9 PFAM Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 452.0
REGS1_k127_419875_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 468.0
REGS1_k127_419875_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 459.0
REGS1_k127_419875_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000001779 208.0
REGS1_k127_4206877_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.219e-309 965.0
REGS1_k127_4206877_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 9.345e-203 635.0
REGS1_k127_4206877_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 367.0
REGS1_k127_4206877_11 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
REGS1_k127_4206877_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 325.0
REGS1_k127_4206877_13 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
REGS1_k127_4206877_14 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000001733 187.0
REGS1_k127_4206877_15 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000003434 145.0
REGS1_k127_4206877_16 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000008379 137.0
REGS1_k127_4206877_17 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.00000000000000000000000000000002093 132.0
REGS1_k127_4206877_18 CHAD - - - 0.000000000000000002258 96.0
REGS1_k127_4206877_19 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000003915 73.0
REGS1_k127_4206877_2 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 607.0
REGS1_k127_4206877_20 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K04749 - - 0.0000003857 61.0
REGS1_k127_4206877_21 PilZ domain - - - 0.0001163 49.0
REGS1_k127_4206877_3 Pro-kumamolisin, activation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 629.0
REGS1_k127_4206877_4 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 597.0
REGS1_k127_4206877_5 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 535.0
REGS1_k127_4206877_6 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 512.0
REGS1_k127_4206877_7 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 496.0
REGS1_k127_4206877_8 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 454.0
REGS1_k127_4206877_9 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 398.0
REGS1_k127_42113_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.648e-200 628.0
REGS1_k127_42113_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 538.0
REGS1_k127_42113_2 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 485.0
REGS1_k127_42113_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 368.0
REGS1_k127_42113_4 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000005371 218.0
REGS1_k127_42113_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000006233 211.0
REGS1_k127_4248586_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1169.0
REGS1_k127_4248586_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.578e-281 875.0
REGS1_k127_4248586_10 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000005799 235.0
REGS1_k127_4248586_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000000000000000000002329 180.0
REGS1_k127_4248586_12 - - - - 0.0000000000000000000000000000000000000004897 154.0
REGS1_k127_4248586_13 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000002121 142.0
REGS1_k127_4248586_14 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000000000000000000009809 119.0
REGS1_k127_4248586_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.00000002535 55.0
REGS1_k127_4248586_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 3.305e-245 794.0
REGS1_k127_4248586_3 Aldehyde dehydrogenase family - - - 2.962e-201 636.0
REGS1_k127_4248586_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 593.0
REGS1_k127_4248586_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 565.0
REGS1_k127_4248586_6 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 418.0
REGS1_k127_4248586_7 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
REGS1_k127_4248586_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 336.0
REGS1_k127_4248586_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 290.0
REGS1_k127_4299234_0 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 393.0
REGS1_k127_4299234_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 303.0
REGS1_k127_4299234_2 - - - - 0.0000000000000000000000000000000000000000001405 171.0
REGS1_k127_4299234_3 DinB superfamily - - - 0.000000000000000000000000000000000000132 148.0
REGS1_k127_4299234_4 Radical SAM domain protein - - - 0.00000000000000000000000000000002951 129.0
REGS1_k127_4299234_5 response to heat K07090 - - 0.0000000000000000000000000006349 116.0
REGS1_k127_4299234_6 - - - - 0.0002152 45.0
REGS1_k127_4319986_0 AMP-binding enzyme K01897 - 6.2.1.3 4.946e-216 688.0
REGS1_k127_4319986_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 399.0
REGS1_k127_4319986_2 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000000002986 61.0
REGS1_k127_4319986_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000003245 57.0
REGS1_k127_4352927_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000599 261.0
REGS1_k127_4352927_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000002952 230.0
REGS1_k127_4352927_2 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000003224 196.0
REGS1_k127_4437108_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 417.0
REGS1_k127_4437108_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 395.0
REGS1_k127_4437108_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000002967 227.0
REGS1_k127_4437108_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000709 151.0
REGS1_k127_4437108_4 - - - - 0.0000003592 53.0
REGS1_k127_448256_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.031e-203 638.0
REGS1_k127_448256_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 587.0
REGS1_k127_448256_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003096 246.0
REGS1_k127_448256_3 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000006271 230.0
REGS1_k127_448256_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002257 181.0
REGS1_k127_462_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 442.0
REGS1_k127_462_1 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000008614 200.0
REGS1_k127_462_2 Arginase family - - - 0.00000000000000000000000000000000000000000000005399 181.0
REGS1_k127_4637755_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1091.0
REGS1_k127_4637755_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 565.0
REGS1_k127_4637755_2 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 371.0
REGS1_k127_4637755_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000002705 141.0
REGS1_k127_4637755_4 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.000000000000000000000000000001748 124.0
REGS1_k127_4637755_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000002072 74.0
REGS1_k127_4641492_0 Peptidase S46 - - - 3.336e-225 719.0
REGS1_k127_4641492_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 594.0
REGS1_k127_4641492_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K04108 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 573.0
REGS1_k127_4641492_3 PFAM aminotransferase class V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 552.0
REGS1_k127_4641492_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 503.0
REGS1_k127_4641492_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002071 280.0
REGS1_k127_4641492_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000565 274.0
REGS1_k127_4641492_7 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002218 269.0
REGS1_k127_4682229_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.256e-269 842.0
REGS1_k127_4682229_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 552.0
REGS1_k127_4682229_2 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 509.0
REGS1_k127_4682229_3 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 518.0
REGS1_k127_4682229_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000001147 151.0
REGS1_k127_4699607_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 514.0
REGS1_k127_4699607_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000004549 95.0
REGS1_k127_4702872_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 307.0
REGS1_k127_4702872_1 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000001497 238.0
REGS1_k127_4702872_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000002947 196.0
REGS1_k127_4702872_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000001072 124.0
REGS1_k127_4734892_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1282.0
REGS1_k127_4734892_1 HELICc2 K03722 - 3.6.4.12 3.057e-268 841.0
REGS1_k127_4734892_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 609.0
REGS1_k127_4734892_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 302.0
REGS1_k127_4734892_4 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000001638 158.0
REGS1_k127_4734892_5 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000004139 127.0
REGS1_k127_4734892_7 hyperosmotic response - - - 0.0000003016 61.0
REGS1_k127_4740222_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002975 278.0
REGS1_k127_4740222_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001094 209.0
REGS1_k127_4740222_2 PilZ domain - - - 0.000000000000000000000008265 105.0
REGS1_k127_4762752_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 359.0
REGS1_k127_4762752_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 297.0
REGS1_k127_4762752_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000004775 231.0
REGS1_k127_4776266_0 signal transduction histidine kinase - - - 1.268e-277 872.0
REGS1_k127_4776266_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 323.0
REGS1_k127_4778710_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 591.0
REGS1_k127_4778710_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000005729 146.0
REGS1_k127_4807283_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 555.0
REGS1_k127_4807283_1 Oligopeptide transporter OPT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 420.0
REGS1_k127_4807283_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 361.0
REGS1_k127_4807283_3 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 302.0
REGS1_k127_4807283_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002657 289.0
REGS1_k127_4807283_5 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000004874 193.0
REGS1_k127_4849400_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 575.0
REGS1_k127_4849400_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000009793 188.0
REGS1_k127_4849459_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1169.0
REGS1_k127_4849459_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.137e-245 762.0
REGS1_k127_4849459_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 4.414e-243 767.0
REGS1_k127_4849459_3 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.883e-224 707.0
REGS1_k127_4849459_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 623.0
REGS1_k127_4849459_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 531.0
REGS1_k127_4849459_6 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000004001 193.0
REGS1_k127_4849459_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000738 168.0
REGS1_k127_4849459_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000001886 152.0
REGS1_k127_4859735_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 455.0
REGS1_k127_4859735_1 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 371.0
REGS1_k127_4859735_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.00000000000000000000000006209 115.0
REGS1_k127_4859735_3 - - - - 0.00000000000000000000008889 100.0
REGS1_k127_4873089_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 520.0
REGS1_k127_4873089_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 507.0
REGS1_k127_4873089_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008061 268.0
REGS1_k127_4873089_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006435 247.0
REGS1_k127_4873089_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006931 250.0
REGS1_k127_4873089_13 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000198 204.0
REGS1_k127_4873089_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000004871 200.0
REGS1_k127_4873089_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001004 217.0
REGS1_k127_4873089_16 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000006234 206.0
REGS1_k127_4873089_17 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000006849 178.0
REGS1_k127_4873089_18 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000005083 179.0
REGS1_k127_4873089_19 - - - - 0.0000000000000000000000000000000000000000000001758 173.0
REGS1_k127_4873089_2 type II secretion system protein K02243,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 468.0
REGS1_k127_4873089_20 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000002979 171.0
REGS1_k127_4873089_21 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000467 154.0
REGS1_k127_4873089_22 PFAM response regulator receiver - - - 0.00000000000000000000000000000007589 132.0
REGS1_k127_4873089_23 GGDEF domain K13590 - 2.7.7.65 0.000000000000000000000000000009731 133.0
REGS1_k127_4873089_24 Thioesterase superfamily - - - 0.000000000000000000451 92.0
REGS1_k127_4873089_25 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000002918 79.0
REGS1_k127_4873089_3 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 430.0
REGS1_k127_4873089_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 361.0
REGS1_k127_4873089_5 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 325.0
REGS1_k127_4873089_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 327.0
REGS1_k127_4873089_7 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 320.0
REGS1_k127_4873089_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
REGS1_k127_4873089_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002601 278.0
REGS1_k127_4882445_0 IgA Peptidase M64 - - - 1.106e-213 672.0
REGS1_k127_4882445_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 294.0
REGS1_k127_4882445_2 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000001438 123.0
REGS1_k127_48858_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 8.861e-227 706.0
REGS1_k127_48858_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 303.0
REGS1_k127_48858_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000882 162.0
REGS1_k127_48858_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000002224 136.0
REGS1_k127_4910187_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009682 284.0
REGS1_k127_4910187_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000001828 145.0
REGS1_k127_4910187_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000009324 87.0
REGS1_k127_4921583_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 9.298e-231 720.0
REGS1_k127_4963081_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008752 272.0
REGS1_k127_4963081_1 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001344 253.0
REGS1_k127_4963081_2 - - - - 0.00000000000000000000000000000000003447 142.0
REGS1_k127_497195_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 4.739e-207 649.0
REGS1_k127_497195_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 331.0
REGS1_k127_497195_2 TIGRFAM TonB K03832 - - 0.0000000002508 64.0
REGS1_k127_4987859_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 486.0
REGS1_k127_4987859_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 452.0
REGS1_k127_4987859_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 439.0
REGS1_k127_4987859_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 290.0
REGS1_k127_4987859_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003378 228.0
REGS1_k127_4987859_5 Transporter associated domain - - - 0.0000000000000000000008417 96.0
REGS1_k127_4987859_6 Domain of unknown function (DUF4412) - - - 0.0000007392 59.0
REGS1_k127_4998245_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 353.0
REGS1_k127_4998245_1 3-isopropylmalate dehydratase K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 294.0
REGS1_k127_4998245_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000003328 265.0
REGS1_k127_4998245_3 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000000000000000000000007113 174.0
REGS1_k127_5003450_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
REGS1_k127_5003450_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000006193 182.0
REGS1_k127_5003450_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000001079 152.0
REGS1_k127_5023579_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 1.675e-263 830.0
REGS1_k127_5023579_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 393.0
REGS1_k127_5023579_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000007233 63.0
REGS1_k127_5023579_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000639 48.0
REGS1_k127_5045416_0 Aldehyde dehydrogenase family K15514 - 1.2.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
REGS1_k127_5045416_1 BON domain - - - 0.0000000000000000000000000000000000000000000000001592 182.0
REGS1_k127_5045416_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000004855 100.0
REGS1_k127_5085894_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.362e-310 974.0
REGS1_k127_5085894_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 604.0
REGS1_k127_5085894_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 507.0
REGS1_k127_5085894_3 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 334.0
REGS1_k127_5085894_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000008406 198.0
REGS1_k127_5085894_5 - - - - 0.0000000000000000471 88.0
REGS1_k127_5107632_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 473.0
REGS1_k127_5107632_1 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 394.0
REGS1_k127_5107632_2 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000003128 210.0
REGS1_k127_5107632_3 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000005618 121.0
REGS1_k127_5135808_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000002286 235.0
REGS1_k127_5135808_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000002288 211.0
REGS1_k127_514605_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 571.0
REGS1_k127_514605_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 550.0
REGS1_k127_514605_10 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000003709 140.0
REGS1_k127_514605_11 Protein of unknown function (DUF2905) - - - 0.0000000000000001089 81.0
REGS1_k127_514605_12 SnoaL-like domain - - - 0.0000000000000001702 93.0
REGS1_k127_514605_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 377.0
REGS1_k127_514605_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 339.0
REGS1_k127_514605_4 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 316.0
REGS1_k127_514605_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000003584 268.0
REGS1_k127_514605_6 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000006956 224.0
REGS1_k127_514605_7 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000001183 210.0
REGS1_k127_514605_8 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000003669 215.0
REGS1_k127_514605_9 Putative thioesterase (yiiD_Cterm) - - - 0.000000000000000000000000000000000000000000000000000000389 197.0
REGS1_k127_515296_0 iron ion homeostasis K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 641.0
REGS1_k127_515296_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 542.0
REGS1_k127_515296_2 ZIP Zinc transporter K07238,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 349.0
REGS1_k127_515296_3 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000006816 179.0
REGS1_k127_5240166_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 1.297e-268 842.0
REGS1_k127_5240166_1 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 1.175e-265 826.0
REGS1_k127_5240166_10 PFAM FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 430.0
REGS1_k127_5240166_11 TrkA-C domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 409.0
REGS1_k127_5240166_12 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 411.0
REGS1_k127_5240166_13 ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 366.0
REGS1_k127_5240166_14 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 329.0
REGS1_k127_5240166_15 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 322.0
REGS1_k127_5240166_16 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
REGS1_k127_5240166_17 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003458 252.0
REGS1_k127_5240166_18 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000004467 244.0
REGS1_k127_5240166_19 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000001091 222.0
REGS1_k127_5240166_2 Secretin and TonB N terminus short domain K02666 - - 8.164e-244 777.0
REGS1_k127_5240166_20 shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000004081 203.0
REGS1_k127_5240166_21 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000007012 192.0
REGS1_k127_5240166_22 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000000000003274 176.0
REGS1_k127_5240166_23 carbon utilization K02664,K02665,K12280 - - 0.0000000000000000000000000000000000000000000001092 176.0
REGS1_k127_5240166_24 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000001098 157.0
REGS1_k127_5240166_26 Helix-turn-helix domain - - - 0.000000000000000000000000000002415 121.0
REGS1_k127_5240166_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.42e-241 752.0
REGS1_k127_5240166_4 amino acid K03294 - - 8.64e-241 754.0
REGS1_k127_5240166_5 amino acid K03294 - - 3.741e-215 679.0
REGS1_k127_5240166_6 cell shape determining protein MreB K03569 - - 7.661e-213 664.0
REGS1_k127_5240166_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 551.0
REGS1_k127_5240166_8 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 537.0
REGS1_k127_5240166_9 Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 517.0
REGS1_k127_5291552_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
REGS1_k127_5291552_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 498.0
REGS1_k127_5291552_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000009353 147.0
REGS1_k127_533594_0 Extracellular solute-binding protein K02027 - - 2.363e-195 632.0
REGS1_k127_533594_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 530.0
REGS1_k127_533594_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 485.0
REGS1_k127_533594_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 448.0
REGS1_k127_533594_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 456.0
REGS1_k127_533594_5 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 286.0
REGS1_k127_533594_6 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002235 276.0
REGS1_k127_533594_7 - - - - 0.0000000000000000000000000000000000000007258 156.0
REGS1_k127_533594_8 - - - - 0.00000000000000007492 88.0
REGS1_k127_5354719_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 420.0
REGS1_k127_5354719_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 354.0
REGS1_k127_5354719_2 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 331.0
REGS1_k127_5409751_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 457.0
REGS1_k127_5409751_1 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 472.0
REGS1_k127_5409751_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 337.0
REGS1_k127_5409751_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002987 257.0
REGS1_k127_5448902_0 xanthine dehydrogenase, a b hammerhead K03520,K19820 - 1.2.5.3,1.5.99.4 9.829e-264 836.0
REGS1_k127_5448902_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 553.0
REGS1_k127_5448902_2 Involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 494.0
REGS1_k127_5448902_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000006657 241.0
REGS1_k127_5448902_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000001619 225.0
REGS1_k127_5448902_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000009547 210.0
REGS1_k127_5448902_6 cyclic nucleotide-binding K01420,K10914 - - 0.000000000000000000000000000000000001449 139.0
REGS1_k127_5448902_7 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000006086 151.0
REGS1_k127_5448902_8 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.0000000000000000000000000000000001031 151.0
REGS1_k127_5448902_9 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000007952 100.0
REGS1_k127_5475857_0 Yip1 domain - - - 0.000000000000000000000000000000000000000000000003412 183.0
REGS1_k127_5475857_1 Selenocysteine synthase N terminal K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000004696 161.0
REGS1_k127_5475857_2 Ferric uptake regulator family K09825 - - 0.0000000000003062 70.0
REGS1_k127_550414_0 Acyl transferase domain - - - 0.0 1163.0
REGS1_k127_5612428_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 579.0
REGS1_k127_5612428_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000003765 174.0
REGS1_k127_5612428_2 Alpha/beta hydrolase family - - - 0.00000000000000000000002645 100.0
REGS1_k127_56177_0 Ammonium Transporter Family K03320 - - 2.6e-254 795.0
REGS1_k127_56177_1 Transporter, CPA2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004507 267.0
REGS1_k127_56177_2 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000001276 168.0
REGS1_k127_56177_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000005811 60.0
REGS1_k127_56177_4 peptidoglycan turnover K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000001233 61.0
REGS1_k127_56177_5 Nacht domain - - - 0.00001511 54.0
REGS1_k127_5720609_0 cellulose binding - - - 2.676e-226 704.0
REGS1_k127_5720609_1 Involved in the tonB-independent uptake of proteins - - - 8.019e-203 659.0
REGS1_k127_5720609_10 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000002059 120.0
REGS1_k127_5720609_11 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000219 106.0
REGS1_k127_5720609_12 PFAM IS1 transposase - - - 0.000000000000000000001664 94.0
REGS1_k127_5720609_13 - - - - 0.0000000004035 64.0
REGS1_k127_5720609_14 PFAM Uncharacterised protein family UPF0150 - - - 0.0000002885 58.0
REGS1_k127_5720609_15 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000057 53.0
REGS1_k127_5720609_16 Cytochrome c K17223 - - 0.00001657 55.0
REGS1_k127_5720609_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 314.0
REGS1_k127_5720609_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000491 277.0
REGS1_k127_5720609_4 Domain of unknown function (DUF4405) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 273.0
REGS1_k127_5720609_5 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000008326 222.0
REGS1_k127_5720609_6 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.00000000000000000000000000000000000000000000004771 176.0
REGS1_k127_5720609_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000000001265 156.0
REGS1_k127_5720609_9 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000007103 121.0
REGS1_k127_5725695_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 4.342e-280 870.0
REGS1_k127_5725695_1 Transglycosylase SLT domain K08309 - - 1.062e-195 634.0
REGS1_k127_575079_0 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 446.0
REGS1_k127_575079_1 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 338.0
REGS1_k127_575079_2 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 321.0
REGS1_k127_575079_3 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000003533 134.0
REGS1_k127_5758298_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 2.472e-223 713.0
REGS1_k127_5758298_1 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 432.0
REGS1_k127_5758298_2 acetaldehyde dehydrogenase (acetylating) - - - 0.0000000000000000000000000000000000000000000000000004338 192.0
REGS1_k127_5758298_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000001955 146.0
REGS1_k127_5758298_4 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000000000000000000000000000000006137 132.0
REGS1_k127_5758298_5 Protein of unknown function (DUF507) - - - 0.00000000000000000000000000001026 128.0
REGS1_k127_5758298_6 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000001934 122.0
REGS1_k127_5787083_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1252.0
REGS1_k127_5787083_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 336.0
REGS1_k127_5794476_0 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 316.0
REGS1_k127_5794476_1 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000002666 245.0
REGS1_k127_5794476_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.00000000000005867 73.0
REGS1_k127_5795244_0 Histidine kinase K02482 - 2.7.13.3 1.483e-289 917.0
REGS1_k127_5795244_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.987e-241 765.0
REGS1_k127_5795244_10 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000002898 166.0
REGS1_k127_5795244_12 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000009499 70.0
REGS1_k127_5795244_13 TIGRFAM TonB family K03832 - - 0.000000000001374 74.0
REGS1_k127_5795244_2 Bacterial regulatory protein, Fis family - - - 3.158e-206 652.0
REGS1_k127_5795244_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 521.0
REGS1_k127_5795244_4 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 467.0
REGS1_k127_5795244_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 455.0
REGS1_k127_5795244_6 Chemotaxis protein CheA K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 421.0
REGS1_k127_5795244_7 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000001548 244.0
REGS1_k127_5795244_8 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
REGS1_k127_5795244_9 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000002979 199.0
REGS1_k127_5796773_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 443.0
REGS1_k127_5796773_1 Superoxide dismutase K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000004971 166.0
REGS1_k127_5804911_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 7.973e-218 691.0
REGS1_k127_5804911_1 Prolyl oligopeptidase K01322 - 3.4.21.26 1.906e-201 649.0
REGS1_k127_5804911_10 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 288.0
REGS1_k127_5804911_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009094 248.0
REGS1_k127_5804911_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005424 228.0
REGS1_k127_5804911_13 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000001405 205.0
REGS1_k127_5804911_14 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000002097 213.0
REGS1_k127_5804911_15 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000004885 213.0
REGS1_k127_5804911_16 PFAM Redoxin - - - 0.0000000000000000000000000000000000000000000000000000008589 199.0
REGS1_k127_5804911_17 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000001619 188.0
REGS1_k127_5804911_18 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000007799 134.0
REGS1_k127_5804911_19 - - - - 0.000000000000000000000000000000006079 130.0
REGS1_k127_5804911_2 Response regulator receiver K07714 - - 1.634e-199 631.0
REGS1_k127_5804911_20 antisigma factor binding K04749 - - 0.000000000000000000000000000001341 126.0
REGS1_k127_5804911_21 Glycosyl transferase family 21 - - - 0.00002599 49.0
REGS1_k127_5804911_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 526.0
REGS1_k127_5804911_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 432.0
REGS1_k127_5804911_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 369.0
REGS1_k127_5804911_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 362.0
REGS1_k127_5804911_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 339.0
REGS1_k127_5804911_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 314.0
REGS1_k127_5804911_9 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 300.0
REGS1_k127_5806216_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.496e-263 818.0
REGS1_k127_5806216_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.504e-204 644.0
REGS1_k127_5806216_2 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 340.0
REGS1_k127_5806216_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000004327 200.0
REGS1_k127_5806216_4 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000007206 187.0
REGS1_k127_5806216_5 - - - - 0.0000000000000000000000000000003208 124.0
REGS1_k127_5813599_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 7.593e-282 897.0
REGS1_k127_5813599_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 302.0
REGS1_k127_5813599_2 FlhB HrpN YscU SpaS Family K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 301.0
REGS1_k127_5813599_3 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007025 280.0
REGS1_k127_5813599_4 flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002715 281.0
REGS1_k127_5813599_5 flagellar biosynthetic protein FliR K02421 - - 0.000000000000000000000000000000000000000000000000000003894 201.0
REGS1_k127_5813599_6 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000005707 103.0
REGS1_k127_5813599_7 Bacterial export proteins, family 3 K02420 - - 0.000000007295 58.0
REGS1_k127_5813599_8 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB - - - 0.0000002509 63.0
REGS1_k127_5826117_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 4.371e-228 717.0
REGS1_k127_5826117_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 447.0
REGS1_k127_5826117_10 XRE family K21498 - - 0.0000000000000000000005335 99.0
REGS1_k127_5826117_11 positive regulation of growth - - - 0.0000000000002376 73.0
REGS1_k127_5826117_2 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 436.0
REGS1_k127_5826117_3 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 406.0
REGS1_k127_5826117_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 402.0
REGS1_k127_5826117_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
REGS1_k127_5826117_6 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 326.0
REGS1_k127_5826117_7 DinB superfamily - - - 0.0000000000000000000000000000000000003113 146.0
REGS1_k127_5826117_8 PIN domain - - - 0.0000000000000000000000000000000002806 135.0
REGS1_k127_5826117_9 PFAM Plasmid maintenance system killer K07334 - - 0.0000000000000000000001358 106.0
REGS1_k127_5849972_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 474.0
REGS1_k127_5849972_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 361.0
REGS1_k127_5849972_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 353.0
REGS1_k127_5849972_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
REGS1_k127_5855734_0 amino acid transport K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 570.0
REGS1_k127_5855734_1 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 514.0
REGS1_k127_5855734_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 402.0
REGS1_k127_5855734_3 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000154 274.0
REGS1_k127_5855734_4 GYD domain - - - 0.00000000000000000000000000000000008732 136.0
REGS1_k127_5855734_5 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000003001 139.0
REGS1_k127_5855734_6 PspC domain K03973 - - 0.0000000000000000000344 93.0
REGS1_k127_5867091_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006084 291.0
REGS1_k127_5867091_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000009007 188.0
REGS1_k127_5867091_2 - - - - 0.0000000000000000000000000000000000000000000003521 182.0
REGS1_k127_5867091_3 Protein of unknown function (DUF1569) - - - 0.0000000000000000001008 96.0
REGS1_k127_588471_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 340.0
REGS1_k127_588471_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000003655 184.0
REGS1_k127_588471_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000006443 141.0
REGS1_k127_588471_3 - - - - 0.000000000009747 68.0
REGS1_k127_588471_4 Glutaredoxin - - - 0.00000004824 56.0
REGS1_k127_5886512_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1020.0
REGS1_k127_5886512_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 6.583e-232 729.0
REGS1_k127_5886512_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 309.0
REGS1_k127_5886512_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 308.0
REGS1_k127_5886512_12 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002816 272.0
REGS1_k127_5886512_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 254.0
REGS1_k127_5886512_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000001213 230.0
REGS1_k127_5886512_15 GAF domain - - - 0.00000000000000000000000000000000000000000000000000003523 193.0
REGS1_k127_5886512_16 - - - - 0.000000000000000000000000000000000000000002192 167.0
REGS1_k127_5886512_17 Pfam:N_methyl_2 - - - 0.00000000000000000000000000000000000001047 153.0
REGS1_k127_5886512_18 phosphorelay signal transduction system - - - 0.000000000000000000000000000005484 134.0
REGS1_k127_5886512_19 Peptidase dimerisation domain K01270 - - 0.000000000000000000000000001068 113.0
REGS1_k127_5886512_2 Belongs to the peptidase M16 family - - - 3.578e-195 617.0
REGS1_k127_5886512_20 - - - - 0.000000000000000000002735 102.0
REGS1_k127_5886512_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 525.0
REGS1_k127_5886512_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 524.0
REGS1_k127_5886512_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 470.0
REGS1_k127_5886512_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 464.0
REGS1_k127_5886512_7 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 476.0
REGS1_k127_5886512_8 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 433.0
REGS1_k127_5886512_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 331.0
REGS1_k127_5900004_0 carbamoyl transferase, NodU family K00612 - - 8.251e-206 655.0
REGS1_k127_5900004_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 512.0
REGS1_k127_5900004_10 Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003475 286.0
REGS1_k127_5900004_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007812 270.0
REGS1_k127_5900004_12 SPTR Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000338 263.0
REGS1_k127_5900004_13 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000001104 252.0
REGS1_k127_5900004_14 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000006175 226.0
REGS1_k127_5900004_15 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000003438 193.0
REGS1_k127_5900004_16 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000004328 199.0
REGS1_k127_5900004_18 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000000000000000001764 177.0
REGS1_k127_5900004_19 radical SAM domain protein - - - 0.000000000000000000000000000000000000000003969 168.0
REGS1_k127_5900004_2 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 484.0
REGS1_k127_5900004_21 Methyltransferase FkbM domain - - - 0.0000000000000000000000000002671 124.0
REGS1_k127_5900004_22 - - - - 0.0000000000000000001625 94.0
REGS1_k127_5900004_23 - - - - 0.0004512 44.0
REGS1_k127_5900004_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 460.0
REGS1_k127_5900004_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 433.0
REGS1_k127_5900004_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 422.0
REGS1_k127_5900004_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 376.0
REGS1_k127_5900004_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 307.0
REGS1_k127_5900004_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 294.0
REGS1_k127_5900004_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000491 294.0
REGS1_k127_5901563_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1272.0
REGS1_k127_5901563_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000137 112.0
REGS1_k127_5939836_0 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 476.0
REGS1_k127_5939836_1 methyltransferase - - - 0.000000000000000000000000000000006603 139.0
REGS1_k127_5939836_2 - - - - 0.000000000000000000000000007842 113.0
REGS1_k127_5939836_4 PFAM Clp amino terminal domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000001334 57.0
REGS1_k127_5942372_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1214.0
REGS1_k127_5942372_1 response regulator, receiver - - - 3.931e-197 618.0
REGS1_k127_5942372_2 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 370.0
REGS1_k127_5942372_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 362.0
REGS1_k127_5942372_4 - - - - 0.000000000000000000000000000271 121.0
REGS1_k127_5942372_5 - - - - 0.0007587 49.0
REGS1_k127_5952887_0 Binding-protein-dependent transport systems inner membrane component K02050 - - 1.211e-230 728.0
REGS1_k127_5952887_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002511 236.0
REGS1_k127_5958840_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000633 212.0
REGS1_k127_5958840_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000001536 142.0
REGS1_k127_5958840_2 - - - - 0.00000000000000000004988 96.0
REGS1_k127_5970148_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.0000000000000000000000000000000000000000000000000000000000112 210.0
REGS1_k127_5970148_1 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000009236 201.0
REGS1_k127_5970148_2 Belongs to the peptidase S8 family - - - 0.000000000000000001864 96.0
REGS1_k127_5975725_0 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000001452 204.0
REGS1_k127_5975725_1 Major facilitator superfamily K08161 - - 0.000000000000000000000000000000000000000000000000000000007147 207.0
REGS1_k127_5975725_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000009349 110.0
REGS1_k127_5975725_3 ATP-independent chaperone mediated protein folding - - - 0.00000000008347 72.0
REGS1_k127_5981721_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000004248 187.0
REGS1_k127_5981721_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000001305 177.0
REGS1_k127_5981721_2 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000001158 74.0
REGS1_k127_6050338_0 acetyltransferase - - - 0.000000000000000000000000000000001114 140.0
REGS1_k127_6050338_1 gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.000000005777 59.0
REGS1_k127_6066621_0 Selenocysteine synthase N terminal K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 608.0
REGS1_k127_6066621_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 401.0
REGS1_k127_6066621_2 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000006589 193.0
REGS1_k127_6066621_3 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000008704 147.0
REGS1_k127_6078283_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.322e-216 680.0
REGS1_k127_6078283_1 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000329 207.0
REGS1_k127_6078283_2 Penicillinase repressor - - - 0.000000000000000000000000000000000000000000000005698 175.0
REGS1_k127_6078283_3 FCD K05799 - - 0.000000000000000000000000000000000000000000006648 171.0
REGS1_k127_6078283_4 Cytochrome P460 - - - 0.000000000005295 67.0
REGS1_k127_6078283_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.00000005061 55.0
REGS1_k127_6080173_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 333.0
REGS1_k127_6080173_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000005743 234.0
REGS1_k127_6080173_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000008182 74.0
REGS1_k127_6080173_11 PD-(D/E)XK endonuclease - - - 0.0000000007049 66.0
REGS1_k127_6080173_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000000000000000000001277 195.0
REGS1_k127_6080173_4 PFAM peptidase K16922 - - 0.00000000000000000000000000000000004461 155.0
REGS1_k127_6080173_5 Transcriptional regulator K07726 - - 0.00000000000000000000000000000001968 129.0
REGS1_k127_6080173_6 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000001138 109.0
REGS1_k127_6080173_7 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.000000000000000000000007736 103.0
REGS1_k127_6080173_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000671 104.0
REGS1_k127_6088092_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 470.0
REGS1_k127_6088092_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000002264 159.0
REGS1_k127_6096080_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 334.0
REGS1_k127_6096080_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008704 222.0
REGS1_k127_6102360_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 371.0
REGS1_k127_6102360_1 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 0.000000000000000000000000000000000000003893 149.0
REGS1_k127_6187995_0 class II (D K K01893 - 6.1.1.22 2.2e-228 716.0
REGS1_k127_6187995_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 593.0
REGS1_k127_6187995_2 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 501.0
REGS1_k127_6187995_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 359.0
REGS1_k127_6187995_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 319.0
REGS1_k127_6187995_5 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000002928 132.0
REGS1_k127_6187995_6 von Willebrand factor, type A - - - 0.00000000000001883 84.0
REGS1_k127_6187995_7 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000006563 70.0
REGS1_k127_6189588_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.288e-270 837.0
REGS1_k127_6189588_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 579.0
REGS1_k127_6189588_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000008497 168.0
REGS1_k127_6222614_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 490.0
REGS1_k127_6222614_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 376.0
REGS1_k127_6271666_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 483.0
REGS1_k127_6271666_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000002345 246.0
REGS1_k127_6271666_2 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000306 106.0
REGS1_k127_6296799_0 PFAM Glycosyl transferase family 2 - - - 3.901e-273 849.0
REGS1_k127_6296799_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 2.422e-200 627.0
REGS1_k127_6296799_10 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K03641 - - 0.00000000006149 75.0
REGS1_k127_6296799_11 YcxB-like protein - - - 0.000001806 59.0
REGS1_k127_6296799_2 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 531.0
REGS1_k127_6296799_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 421.0
REGS1_k127_6296799_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 320.0
REGS1_k127_6296799_5 chaperone-mediated protein folding K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003135 228.0
REGS1_k127_6296799_6 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000001633 136.0
REGS1_k127_6296799_7 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000001779 107.0
REGS1_k127_6296799_8 HicB family K18843 - - 0.000000000000000000000759 104.0
REGS1_k127_6296799_9 Helix-hairpin-helix motif - - - 0.00000000000000006969 85.0
REGS1_k127_6298937_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 491.0
REGS1_k127_6298937_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 303.0
REGS1_k127_6298937_2 Cold shock protein domain K03704 - - 0.000000000000000000004164 92.0
REGS1_k127_6298937_3 - - - - 0.000000000008372 72.0
REGS1_k127_6300072_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 543.0
REGS1_k127_6300072_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 436.0
REGS1_k127_6300072_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008677 290.0
REGS1_k127_6300072_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005423 252.0
REGS1_k127_6300072_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000001994 173.0
REGS1_k127_6300072_5 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000002239 166.0
REGS1_k127_6300072_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000007629 106.0
REGS1_k127_6300072_7 cellulose binding - - - 0.00000000000003807 85.0
REGS1_k127_6300331_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 587.0
REGS1_k127_6300331_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 366.0
REGS1_k127_6300331_3 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000155 231.0
REGS1_k127_6300331_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000001503 161.0
REGS1_k127_6300331_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000502 88.0
REGS1_k127_6352570_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 578.0
REGS1_k127_6352570_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 385.0
REGS1_k127_6382437_0 PAS domain - - - 1.126e-239 758.0
REGS1_k127_6382437_1 Sigma-54 interaction domain - - - 2.608e-219 691.0
REGS1_k127_6382437_10 PilZ domain - - - 0.000004109 53.0
REGS1_k127_6382437_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 441.0
REGS1_k127_6382437_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 437.0
REGS1_k127_6382437_4 Bacterial regulatory protein, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 357.0
REGS1_k127_6382437_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 319.0
REGS1_k127_6382437_6 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000002102 147.0
REGS1_k127_6382437_7 - - - - 0.000000000000000002317 93.0
REGS1_k127_6382437_8 - - - - 0.000000000006823 71.0
REGS1_k127_6382437_9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000002666 59.0
REGS1_k127_6504507_0 dead deah K03724 - - 0.0 1347.0
REGS1_k127_6504507_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0 1071.0
REGS1_k127_6504507_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.284e-271 855.0
REGS1_k127_6504507_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 329.0
REGS1_k127_6504507_4 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
REGS1_k127_6504507_5 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000000000000000000000002817 151.0
REGS1_k127_6504507_9 Tetratricopeptide repeat - - - 0.000000000000002798 89.0
REGS1_k127_6509480_0 COGs COG4584 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000002392 255.0
REGS1_k127_6509480_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000004658 162.0
REGS1_k127_6509480_3 transposition - - - 0.00000000000000000000000000003214 119.0
REGS1_k127_6509480_4 chromosome segregation - - - 0.0000000000000002113 90.0
REGS1_k127_6529384_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000006356 208.0
REGS1_k127_6529384_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000003653 188.0
REGS1_k127_6529384_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000001644 154.0
REGS1_k127_663722_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.238e-219 689.0
REGS1_k127_663722_1 Glycosyl hydrolase family 57 - - - 1.058e-196 628.0
REGS1_k127_663722_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 340.0
REGS1_k127_663722_3 - - - - 0.00000000000000000000000000009831 127.0
REGS1_k127_663722_4 - - - - 0.000000000003887 77.0
REGS1_k127_663722_5 peroxiredoxin activity K03564 - 1.11.1.15 0.0000001027 58.0
REGS1_k127_663722_6 COG1225 Peroxiredoxin - - - 0.00001208 48.0
REGS1_k127_667334_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1047.0
REGS1_k127_667334_1 TonB-dependent Receptor Plug Domain K02014,K16092 - - 4.228e-237 754.0
REGS1_k127_667334_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 378.0
REGS1_k127_667334_11 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 375.0
REGS1_k127_667334_12 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 355.0
REGS1_k127_667334_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 327.0
REGS1_k127_667334_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
REGS1_k127_667334_15 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000001032 208.0
REGS1_k127_667334_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000008811 202.0
REGS1_k127_667334_17 DUF218 domain - - - 0.000000000000000000000000000000000000000005266 161.0
REGS1_k127_667334_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000003143 133.0
REGS1_k127_667334_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 1.976e-211 668.0
REGS1_k127_667334_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000003427 130.0
REGS1_k127_667334_21 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000586 113.0
REGS1_k127_667334_23 GGDEF domain - - - 0.00000000467 66.0
REGS1_k127_667334_25 - - - - 0.00085 45.0
REGS1_k127_667334_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.401e-208 656.0
REGS1_k127_667334_4 alpha beta alpha domain I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 619.0
REGS1_k127_667334_5 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 581.0
REGS1_k127_667334_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 572.0
REGS1_k127_667334_7 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 503.0
REGS1_k127_667334_8 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 494.0
REGS1_k127_667334_9 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 430.0
REGS1_k127_6685584_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1337.0
REGS1_k127_6685584_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 8.454e-267 846.0
REGS1_k127_6685584_2 Tetratricopeptide repeat - - - 4.877e-263 828.0
REGS1_k127_6685584_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 518.0
REGS1_k127_6685584_4 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 359.0
REGS1_k127_6685584_5 - - - - 0.0000000000258 72.0
REGS1_k127_6685584_6 cAMP biosynthetic process K03641 - - 0.00000000008326 66.0
REGS1_k127_6790208_0 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 424.0
REGS1_k127_6790208_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000002063 254.0
REGS1_k127_6790208_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000007444 236.0
REGS1_k127_6790208_3 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000000000122 220.0
REGS1_k127_6790208_4 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000001791 169.0
REGS1_k127_6924764_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 536.0
REGS1_k127_6924764_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 424.0
REGS1_k127_6927637_0 Beta-Casp domain K07576 - - 3.058e-233 729.0
REGS1_k127_6927637_1 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 402.0
REGS1_k127_6928002_0 DDE superfamily endonuclease - - - 0.000000000000000000000000001532 119.0
REGS1_k127_6928002_1 Winged helix-turn helix - - - 0.000000000000000000000001511 109.0
REGS1_k127_6928002_2 transcriptional regulator, SARP family - - - 0.0008115 50.0
REGS1_k127_6928185_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.192e-203 638.0
REGS1_k127_6928185_1 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000005576 231.0
REGS1_k127_6928185_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001538 238.0
REGS1_k127_6928185_3 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000001069 171.0
REGS1_k127_69470_0 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 1.699e-225 707.0
REGS1_k127_69470_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 455.0
REGS1_k127_6947323_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002792 260.0
REGS1_k127_6947323_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000008849 211.0
REGS1_k127_696620_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 473.0
REGS1_k127_696620_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
REGS1_k127_696620_2 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000111 75.0
REGS1_k127_6972855_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.585e-281 872.0
REGS1_k127_6972855_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 466.0
REGS1_k127_6972855_10 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000001301 237.0
REGS1_k127_6972855_11 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000002217 224.0
REGS1_k127_6972855_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000005055 217.0
REGS1_k127_6972855_13 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000000003826 90.0
REGS1_k127_6972855_14 - - - - 0.0000000000189 71.0
REGS1_k127_6972855_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 405.0
REGS1_k127_6972855_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 407.0
REGS1_k127_6972855_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 360.0
REGS1_k127_6972855_5 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 309.0
REGS1_k127_6972855_6 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 321.0
REGS1_k127_6972855_7 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 310.0
REGS1_k127_6972855_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009382 256.0
REGS1_k127_6972855_9 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
REGS1_k127_6985481_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 470.0
REGS1_k127_6985481_1 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 397.0
REGS1_k127_6985481_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000003019 199.0
REGS1_k127_6985481_3 BON domain - - - 0.00000000000000000000000000000000000000000000000004372 191.0
REGS1_k127_6986582_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 486.0
REGS1_k127_6986582_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 294.0
REGS1_k127_6986582_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000004572 231.0
REGS1_k127_6986582_3 Gaf domain K03832 - - 0.00000000000000000000000000000000004537 153.0
REGS1_k127_6986582_4 protein secretion K03116 - - 0.0000000000001556 74.0
REGS1_k127_7001902_0 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000004931 245.0
REGS1_k127_7001902_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000231 85.0
REGS1_k127_7001902_2 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain - - - 0.0004643 49.0
REGS1_k127_7007604_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 411.0
REGS1_k127_7007604_1 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 306.0
REGS1_k127_7007604_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004477 256.0
REGS1_k127_7007604_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000002608 219.0
REGS1_k127_7016686_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001061 241.0
REGS1_k127_7016686_1 Protein of unknown function (DUF3617) - - - 0.00000000000000000005142 96.0
REGS1_k127_7017746_0 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 257.0
REGS1_k127_7017746_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000003115 220.0
REGS1_k127_7017746_2 - - - - 0.00000000000000000000005294 108.0
REGS1_k127_7017746_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000004698 68.0
REGS1_k127_7017746_4 Memo-like protein K06990 - - 0.000000000006002 65.0
REGS1_k127_704801_0 Abhydrolase domain containing 18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 493.0
REGS1_k127_704801_1 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 382.0
REGS1_k127_704801_2 Ribose/Galactose Isomerase K01808,K01819,K21911 GO:0003674,GO:0003824,GO:0004751,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.26,5.3.1.34,5.3.1.6 0.0000000000000000000000000000000000000000000000000000001036 199.0
REGS1_k127_704801_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000003517 170.0
REGS1_k127_7048386_0 Mur ligase middle domain K02558 - 6.3.2.45 1.231e-210 670.0
REGS1_k127_7048386_1 PFAM peptidase M61 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 492.0
REGS1_k127_7048386_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000002901 223.0
REGS1_k127_7048386_11 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000003635 145.0
REGS1_k127_7048386_12 GtrA-like protein - - - 0.00000000000000000000000000000000785 134.0
REGS1_k127_7048386_13 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000002292 72.0
REGS1_k127_7048386_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 465.0
REGS1_k127_7048386_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 440.0
REGS1_k127_7048386_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 400.0
REGS1_k127_7048386_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
REGS1_k127_7048386_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
REGS1_k127_7048386_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008655 278.0
REGS1_k127_7048386_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
REGS1_k127_7048386_9 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004755 246.0
REGS1_k127_7048445_0 4Fe-4S dicluster domain K00184 - - 0.0 1153.0
REGS1_k127_7048445_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 377.0
REGS1_k127_7048445_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000001717 63.0
REGS1_k127_7050823_0 Heat shock 70 kDa protein K04043 - - 0.0 1061.0
REGS1_k127_7050823_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.987e-272 845.0
REGS1_k127_7050823_2 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 286.0
REGS1_k127_7050823_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000182 187.0
REGS1_k127_7062523_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 1.616e-306 945.0
REGS1_k127_7062523_1 response regulator, receiver K02667 - - 1.875e-202 639.0
REGS1_k127_7062523_2 Type II/IV secretion system protein K02669 - - 7.128e-198 621.0
REGS1_k127_7062523_3 PFAM Type II secretion system F domain K02653 - - 5.092e-195 614.0
REGS1_k127_7062523_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 602.0
REGS1_k127_7062523_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 550.0
REGS1_k127_7062523_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 326.0
REGS1_k127_7062523_7 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000006331 209.0
REGS1_k127_7062523_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000002061 178.0
REGS1_k127_7062523_9 - - - - 0.0000000000000000000000000000000000004519 140.0
REGS1_k127_70644_0 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 567.0
REGS1_k127_70644_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 528.0
REGS1_k127_70644_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 501.0
REGS1_k127_70644_3 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 393.0
REGS1_k127_70644_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007011 280.0
REGS1_k127_70644_5 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000001033 264.0
REGS1_k127_70644_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000001135 186.0
REGS1_k127_70644_7 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000000000000000000364 187.0
REGS1_k127_70644_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000002217 139.0
REGS1_k127_70644_9 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000001815 98.0
REGS1_k127_7066444_0 Radical SAM - - - 0.0 1139.0
REGS1_k127_7066444_1 cellulose binding - - - 0.0 1080.0
REGS1_k127_7066444_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 610.0
REGS1_k127_7066444_3 Radical SAM superfamily K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 521.0
REGS1_k127_7066444_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000001864 239.0
REGS1_k127_7066444_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000001553 225.0
REGS1_k127_7066444_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000002261 200.0
REGS1_k127_7066444_7 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000002069 175.0
REGS1_k127_7077169_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 576.0
REGS1_k127_7077169_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 447.0
REGS1_k127_7077169_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 377.0
REGS1_k127_7077169_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 296.0
REGS1_k127_7077169_4 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000000002097 151.0
REGS1_k127_7078072_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 486.0
REGS1_k127_7078072_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000456 265.0
REGS1_k127_7085901_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 409.0
REGS1_k127_7085901_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 369.0
REGS1_k127_7088393_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1135.0
REGS1_k127_7088393_1 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 414.0
REGS1_k127_7088393_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 378.0
REGS1_k127_7104385_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 579.0
REGS1_k127_7104385_1 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 339.0
REGS1_k127_7104385_2 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 310.0
REGS1_k127_7104385_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 277.0
REGS1_k127_7104385_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 274.0
REGS1_k127_7104385_5 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000138 235.0
REGS1_k127_7104385_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000009752 214.0
REGS1_k127_7104385_7 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000005886 176.0
REGS1_k127_7108969_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 537.0
REGS1_k127_7108969_2 - - - - 0.0000000000000000000000000000000004129 137.0
REGS1_k127_7120267_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 575.0
REGS1_k127_7163056_0 Oligopeptide transporter OPT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 541.0
REGS1_k127_7163056_1 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 531.0
REGS1_k127_7163056_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 458.0
REGS1_k127_7163056_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 324.0
REGS1_k127_7163056_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001176 277.0
REGS1_k127_7163056_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000019 257.0
REGS1_k127_7163056_6 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000000000000000000000000293 228.0
REGS1_k127_7163056_7 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000000000000002719 199.0
REGS1_k127_7163056_8 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000006128 113.0
REGS1_k127_7163056_9 - - - - 0.000000191 61.0
REGS1_k127_7236678_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1169.0
REGS1_k127_7236678_1 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 515.0
REGS1_k127_7236678_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001301 113.0
REGS1_k127_7236678_11 Ferredoxin, 2Fe-2S - - - 0.00000000000000000004047 104.0
REGS1_k127_7236678_2 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 474.0
REGS1_k127_7236678_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 402.0
REGS1_k127_7236678_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 357.0
REGS1_k127_7236678_5 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 318.0
REGS1_k127_7236678_6 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001719 264.0
REGS1_k127_7236678_7 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000004973 243.0
REGS1_k127_7236678_8 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000003301 223.0
REGS1_k127_7236678_9 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.00000000000000000000000000000000000000000000000000003763 198.0
REGS1_k127_7251626_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.037e-270 841.0
REGS1_k127_7251626_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 1.035e-247 775.0
REGS1_k127_7251626_10 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 256.0
REGS1_k127_7251626_11 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000003062 188.0
REGS1_k127_7251626_12 PFAM Dynamin family protein - - - 0.000000000000000000000000000000000000000000000000005868 202.0
REGS1_k127_7251626_13 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000008268 170.0
REGS1_k127_7251626_15 RNA recognition motif - - - 0.000000000000000000000000000004183 124.0
REGS1_k127_7251626_16 methyltransferase activity - - - 0.000000000000000000000002715 116.0
REGS1_k127_7251626_18 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000004129 87.0
REGS1_k127_7251626_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000462 79.0
REGS1_k127_7251626_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 410.0
REGS1_k127_7251626_20 Class III cytochrome C family - - - 0.00000000000000425 80.0
REGS1_k127_7251626_21 Luciferase-like monooxygenase - - - 0.000000000003369 68.0
REGS1_k127_7251626_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 391.0
REGS1_k127_7251626_4 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 351.0
REGS1_k127_7251626_5 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 312.0
REGS1_k127_7251626_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 310.0
REGS1_k127_7251626_7 PFAM Cytochrome c assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 290.0
REGS1_k127_7251626_8 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001518 285.0
REGS1_k127_7251626_9 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001018 263.0
REGS1_k127_72565_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1153.0
REGS1_k127_72565_1 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1116.0
REGS1_k127_72565_10 PhoQ Sensor - - - 0.00000000000000000000003688 107.0
REGS1_k127_72565_11 Domain of unknown function (DUF4372) - - - 0.000000625 58.0
REGS1_k127_72565_2 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 548.0
REGS1_k127_72565_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001093 278.0
REGS1_k127_72565_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
REGS1_k127_72565_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
REGS1_k127_72565_6 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
REGS1_k127_72565_7 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000000000000000000006345 177.0
REGS1_k127_72565_8 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.00000000000000000000000000000000000000000000001897 189.0
REGS1_k127_72565_9 chlorophyll binding - - - 0.0000000000000000000000000000000001885 145.0
REGS1_k127_726504_0 cellulose binding - - - 5.692e-233 762.0
REGS1_k127_726504_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 577.0
REGS1_k127_726504_2 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 559.0
REGS1_k127_726504_3 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 357.0
REGS1_k127_726504_4 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 332.0
REGS1_k127_726504_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
REGS1_k127_726504_6 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
REGS1_k127_726504_7 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000007839 193.0
REGS1_k127_726504_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000006236 150.0
REGS1_k127_726504_9 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000001674 136.0
REGS1_k127_7269965_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1288.0
REGS1_k127_7269965_1 PFAM Cytochrome c assembly protein K02198 - - 2.202e-311 966.0
REGS1_k127_7269965_10 PFAM response regulator receiver - - - 0.00000000000000000000000000000007302 127.0
REGS1_k127_7269965_11 Response regulator, receiver K10819,K20975 - 2.7.13.3 0.0000000000000000000000002984 111.0
REGS1_k127_7269965_12 - - - - 0.000000000000000000000002994 105.0
REGS1_k127_7269965_13 cyclic nucleotide binding K07001,K10914 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000003929 108.0
REGS1_k127_7269965_14 - - - - 0.00000000000000000003145 91.0
REGS1_k127_7269965_15 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000004523 91.0
REGS1_k127_7269965_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 570.0
REGS1_k127_7269965_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 483.0
REGS1_k127_7269965_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 374.0
REGS1_k127_7269965_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 357.0
REGS1_k127_7269965_6 recA bacterial DNA recombination protein - - - 0.00000000000000000000000000000000000000000000000001335 190.0
REGS1_k127_7269965_8 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000001948 145.0
REGS1_k127_7269965_9 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000002024 143.0
REGS1_k127_7281215_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.281e-238 739.0
REGS1_k127_7281215_1 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000004152 195.0
REGS1_k127_7281443_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 1.556e-225 707.0
REGS1_k127_7281443_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 544.0
REGS1_k127_7281443_2 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 523.0
REGS1_k127_7281443_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000003183 112.0
REGS1_k127_7281443_4 Zinc iron permease K07238 - - 0.000009229 49.0
REGS1_k127_7295498_0 Glycosyltransferase family 20 - - - 4.244e-270 854.0
REGS1_k127_7295498_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 612.0
REGS1_k127_7295498_10 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000000000000001706 142.0
REGS1_k127_7295498_11 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000008057 134.0
REGS1_k127_7295498_12 Glutaredoxin - - - 0.00000000000000002031 83.0
REGS1_k127_7295498_13 antisigma factor binding - - - 0.000000001861 68.0
REGS1_k127_7295498_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0007098 51.0
REGS1_k127_7295498_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 553.0
REGS1_k127_7295498_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 469.0
REGS1_k127_7295498_4 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 401.0
REGS1_k127_7295498_5 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 314.0
REGS1_k127_7295498_6 TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000000000000000000000001456 243.0
REGS1_k127_7295498_7 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
REGS1_k127_7295498_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000003194 231.0
REGS1_k127_7295498_9 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000001094 163.0
REGS1_k127_7326283_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 5.459e-203 638.0
REGS1_k127_7326283_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 411.0
REGS1_k127_7326283_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000001583 116.0
REGS1_k127_7326283_3 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000005519 109.0
REGS1_k127_7329267_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 2.255e-210 658.0
REGS1_k127_7329267_1 dead deah K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 582.0
REGS1_k127_7329267_3 DEAD/H associated K03724 - - 0.00000000000000000000000000000001471 133.0
REGS1_k127_7333052_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 438.0
REGS1_k127_7333052_1 DNA-dependent DNA replication - - - 0.00000001408 56.0
REGS1_k127_73350_0 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000009037 107.0
REGS1_k127_73350_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000003689 116.0
REGS1_k127_73350_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000009253 65.0
REGS1_k127_7340514_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1474.0
REGS1_k127_7349793_0 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
REGS1_k127_7349793_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 344.0
REGS1_k127_7349793_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 349.0
REGS1_k127_7349793_3 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 321.0
REGS1_k127_7349793_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 294.0
REGS1_k127_7349793_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002011 241.0
REGS1_k127_7349793_6 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000008682 155.0
REGS1_k127_7371780_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 4.963e-245 779.0
REGS1_k127_7371780_1 PA domain - - - 2.352e-226 713.0
REGS1_k127_7371780_2 Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 555.0
REGS1_k127_7371780_3 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 331.0
REGS1_k127_7371780_4 Redoxin - - - 0.000000000000000000000000000000000000000002135 162.0
REGS1_k127_7371780_6 Type II transport protein GspH K08084 - - 0.00008184 52.0
REGS1_k127_7371780_8 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0002204 49.0
REGS1_k127_7377417_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 1.044e-267 835.0
REGS1_k127_7377417_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000009399 175.0
REGS1_k127_7383663_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 417.0
REGS1_k127_7383663_1 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 298.0
REGS1_k127_7383663_2 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00000000000000000000000000000000007939 137.0
REGS1_k127_738874_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 537.0
REGS1_k127_738874_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 517.0
REGS1_k127_738874_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 320.0
REGS1_k127_738874_3 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001965 286.0
REGS1_k127_738874_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 233.0
REGS1_k127_738874_5 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000004524 218.0
REGS1_k127_738874_6 response to abiotic stimulus - - - 0.000000000000000000000000000000000000000000002485 173.0
REGS1_k127_738874_7 - - - - 0.000000000000001316 78.0
REGS1_k127_7477206_0 ASPIC and UnbV - - - 0.0 1097.0
REGS1_k127_7477206_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 6.137e-263 830.0
REGS1_k127_7477206_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 483.0
REGS1_k127_7477206_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000091 282.0
REGS1_k127_7477206_4 citrate CoA-transferase activity K01643 - 2.8.3.10 0.0000000003779 60.0
REGS1_k127_7508046_0 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 421.0
REGS1_k127_7508046_1 Mov34 MPN PAD-1 - - - 0.000000000000000000000000000000000000000000000000000000000001409 213.0
REGS1_k127_7508046_2 - - - - 0.000000000000000000000000000000000000000000000000000000006346 203.0
REGS1_k127_7508046_3 ThiS family K03636 - - 0.00000000000000000000000000000000001392 137.0
REGS1_k127_7583959_0 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 531.0
REGS1_k127_7583959_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 536.0
REGS1_k127_7583959_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 382.0
REGS1_k127_7583959_3 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 342.0
REGS1_k127_7583959_4 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000000000000000000002952 189.0
REGS1_k127_7583959_5 - - - - 0.00000000000000000000000000000000000000000000001822 175.0
REGS1_k127_7583959_6 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000004867 105.0
REGS1_k127_7583959_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00002656 46.0
REGS1_k127_7586969_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 407.0
REGS1_k127_7586969_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 351.0
REGS1_k127_7586969_3 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001462 277.0
REGS1_k127_7586969_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001499 216.0
REGS1_k127_7586969_5 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000002315 216.0
REGS1_k127_7586969_6 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000003724 196.0
REGS1_k127_7586969_7 Hfq protein K03666 - - 0.0000000000000000000000000000000001022 134.0
REGS1_k127_7586969_8 - - - - 0.00000000000000000005391 94.0
REGS1_k127_7619197_0 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 491.0
REGS1_k127_7619197_1 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000003187 214.0
REGS1_k127_7619197_2 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000003903 174.0
REGS1_k127_7619197_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000007983 159.0
REGS1_k127_76820_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 410.0
REGS1_k127_76820_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
REGS1_k127_7686869_0 conserved protein containing a ferredoxin-like domain - - - 4.893e-206 668.0
REGS1_k127_7686869_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 589.0
REGS1_k127_7686869_10 BON domain - - - 0.000000000000000000000000000234 130.0
REGS1_k127_7686869_11 Bacterial regulatory protein, Fis family - - - 0.000000000000000000001069 97.0
REGS1_k127_7686869_12 LUD domain K00782 - - 0.0000000000000000000119 105.0
REGS1_k127_7686869_13 phage integrase domain protein SAM domain protein - - - 0.0000000000000000003475 90.0
REGS1_k127_7686869_14 COG0457 FOG TPR repeat - - - 0.00000001369 67.0
REGS1_k127_7686869_15 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000004926 57.0
REGS1_k127_7686869_16 PD-(D/E)XK endonuclease - - - 0.00003667 52.0
REGS1_k127_7686869_17 Ntpase (Nacht family) - - - 0.00004554 55.0
REGS1_k127_7686869_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 399.0
REGS1_k127_7686869_3 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
REGS1_k127_7686869_4 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 375.0
REGS1_k127_7686869_5 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 371.0
REGS1_k127_7686869_6 Abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 317.0
REGS1_k127_7686869_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 296.0
REGS1_k127_7686869_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000001039 156.0
REGS1_k127_7686869_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000005366 151.0
REGS1_k127_769402_0 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000161 209.0
REGS1_k127_769402_1 TPR repeat-containing protein - - - 0.0000000000000000000000000000001272 141.0
REGS1_k127_7695364_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 0.0 1026.0
REGS1_k127_7695364_1 Belongs to the GSP D family K02453 - - 5.552e-251 799.0
REGS1_k127_7695364_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
REGS1_k127_7695364_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000000000002135 214.0
REGS1_k127_7695364_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000001526 169.0
REGS1_k127_7695364_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000131 164.0
REGS1_k127_7695364_6 DinB family - - - 0.0000002995 57.0
REGS1_k127_7711300_0 Type II transport protein GspH K08084 - - 0.0001892 51.0
REGS1_k127_778720_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 3.535e-230 716.0
REGS1_k127_778720_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 289.0
REGS1_k127_778720_2 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000001788 176.0
REGS1_k127_778720_3 PIN domain - - - 0.000000000000000000000000005263 115.0
REGS1_k127_778720_4 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000001643 72.0
REGS1_k127_7803206_0 cellulose binding - - - 7.537e-282 884.0
REGS1_k127_7818399_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 6.056e-296 954.0
REGS1_k127_7818399_1 surface antigen variable number - - - 7.78e-283 906.0
REGS1_k127_7818399_2 Elongator protein 3, MiaB family, Radical SAM - - - 6.142e-196 617.0
REGS1_k127_7818399_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 575.0
REGS1_k127_7818399_4 MoeZ MoeB K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 517.0
REGS1_k127_7818399_5 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 406.0
REGS1_k127_7818399_6 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 353.0
REGS1_k127_7818399_7 Asparaginase K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 330.0
REGS1_k127_7818399_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 302.0
REGS1_k127_7818399_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000001151 144.0
REGS1_k127_782008_0 Permease, YjgP YjgQ - - - 1.021e-319 995.0
REGS1_k127_782008_1 ABC transporter K06158 - - 1.306e-287 901.0
REGS1_k127_782008_10 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
REGS1_k127_782008_11 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007851 274.0
REGS1_k127_782008_12 Glucose inhibited division protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003283 257.0
REGS1_k127_782008_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009188 235.0
REGS1_k127_782008_14 Cytochrome b/b6/petB K00127 - - 0.00000000000000000000000000000000000000000000000000000000000007375 225.0
REGS1_k127_782008_15 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000009652 220.0
REGS1_k127_782008_16 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001903 214.0
REGS1_k127_782008_17 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000005924 220.0
REGS1_k127_782008_18 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000000000000000000000000002675 194.0
REGS1_k127_782008_19 methyltransferase - - - 0.00000000000000000000000000000000000000000000000003534 190.0
REGS1_k127_782008_2 ABC transporter, transmembrane K18889 - - 5.774e-264 825.0
REGS1_k127_782008_20 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000001516 181.0
REGS1_k127_782008_21 serine-type peptidase activity K01061,K06889 - 3.1.1.45 0.000000000000000000000000000000000000000000007666 176.0
REGS1_k127_782008_22 Beta subunit K00124 - - 0.00000000000000000000000000000000000000000297 159.0
REGS1_k127_782008_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 555.0
REGS1_k127_782008_4 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 459.0
REGS1_k127_782008_5 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 444.0
REGS1_k127_782008_6 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 385.0
REGS1_k127_782008_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 361.0
REGS1_k127_782008_8 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 332.0
REGS1_k127_782008_9 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 334.0
REGS1_k127_7858538_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 449.0
REGS1_k127_7858538_1 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 411.0
REGS1_k127_7858538_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 408.0
REGS1_k127_7858538_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 373.0
REGS1_k127_7941300_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 434.0
REGS1_k127_7941300_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
REGS1_k127_7941300_2 Evidence 4 Homologs of previously reported genes of K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001555 282.0
REGS1_k127_7941300_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001998 271.0
REGS1_k127_7941300_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000007622 248.0
REGS1_k127_7941300_5 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000006658 121.0
REGS1_k127_7941300_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000002905 77.0
REGS1_k127_7941300_7 SNARE associated Golgi protein - - - 0.00000000002958 64.0
REGS1_k127_7941300_8 Antioxidant, AhpC TSA family K03564 - 1.11.1.15 0.0000000002149 65.0
REGS1_k127_7941300_9 - - - - 0.000000006317 64.0
REGS1_k127_8088434_0 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 364.0
REGS1_k127_8088434_1 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000009071 192.0
REGS1_k127_8088766_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.187e-312 964.0
REGS1_k127_8088766_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000000000007587 198.0
REGS1_k127_8088766_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000003423 158.0
REGS1_k127_8088766_3 - - - - 0.00000000000000005347 88.0
REGS1_k127_8106653_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.223e-250 812.0
REGS1_k127_8106653_1 PFAM Response regulator receiver domain K07713 - - 3.485e-247 771.0
REGS1_k127_8106653_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 616.0
REGS1_k127_8106653_3 - - - - 0.0000000000000000000000000000000000001291 161.0
REGS1_k127_8106653_5 TIM-barrel fold metal-dependent hydrolase K07045 - - 0.0000000000000000002801 98.0
REGS1_k127_8119185_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1046.0
REGS1_k127_8119185_1 His Kinase A (phosphoacceptor) domain - - - 8.114e-212 672.0
REGS1_k127_8119185_10 Thioesterase superfamily - - - 0.000000000000000000000000000000000005672 142.0
REGS1_k127_8119185_11 MerR, DNA binding - - - 0.00000000000000000000000000895 115.0
REGS1_k127_8119185_12 - - - - 0.00000000000000000000000007999 110.0
REGS1_k127_8119185_13 antisigma factor binding - - - 0.00000000000000000002178 99.0
REGS1_k127_8119185_14 extracellular matrix structural constituent - - - 0.000000000001657 79.0
REGS1_k127_8119185_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 578.0
REGS1_k127_8119185_3 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 516.0
REGS1_k127_8119185_4 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 477.0
REGS1_k127_8119185_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008718 259.0
REGS1_k127_8119185_6 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
REGS1_k127_8119185_7 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000000000000000000002348 223.0
REGS1_k127_8119185_8 methyltransferase - - - 0.0000000000000000000000000000000000000000002013 165.0
REGS1_k127_8119185_9 Pfam:N_methyl_2 - - - 0.00000000000000000000000000000000000000001184 158.0
REGS1_k127_8127820_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
REGS1_k127_8127820_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000244 176.0
REGS1_k127_8130248_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 399.0
REGS1_k127_8130248_1 Transcriptional regulatory protein, C terminal K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 307.0
REGS1_k127_8130248_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 295.0
REGS1_k127_8130248_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 301.0
REGS1_k127_8131958_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 419.0
REGS1_k127_8131958_1 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 394.0
REGS1_k127_8131958_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
REGS1_k127_8131958_3 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 288.0
REGS1_k127_8131958_4 Aminotransferase class-V K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000002453 226.0
REGS1_k127_8131958_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000009483 138.0
REGS1_k127_8131958_6 - - - - 0.0000000000000000000000004487 107.0
REGS1_k127_8132142_0 Tetratricopeptide repeat - - - 1.104e-258 828.0
REGS1_k127_8132142_1 metalloendopeptidase activity K01283 - 3.4.15.1 2.406e-243 768.0
REGS1_k127_8132142_10 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000415 64.0
REGS1_k127_8132142_2 acetyl-CoA hydrolase K18118 - 2.8.3.18 2.629e-239 749.0
REGS1_k127_8132142_3 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 501.0
REGS1_k127_8132142_4 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 486.0
REGS1_k127_8132142_5 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 450.0
REGS1_k127_8132142_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 396.0
REGS1_k127_8132142_7 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000003379 196.0
REGS1_k127_8132142_8 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000003453 114.0
REGS1_k127_8132142_9 - - - - 0.0000000000000000000000005166 108.0
REGS1_k127_8133126_0 Aromatic amino acid lyase K01745 - 4.3.1.3 4.91e-220 694.0
REGS1_k127_8133126_1 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 394.0
REGS1_k127_8133126_10 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000004199 57.0
REGS1_k127_8133126_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 355.0
REGS1_k127_8133126_3 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 312.0
REGS1_k127_8133126_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 299.0
REGS1_k127_8133126_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003016 243.0
REGS1_k127_8133126_6 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000004286 233.0
REGS1_k127_8133126_7 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000000006266 181.0
REGS1_k127_8133126_8 O-methyltransferase activity - - - 0.0000000000000000001402 99.0
REGS1_k127_8133126_9 SnoaL-like polyketide cyclase - - - 0.000000000417 65.0
REGS1_k127_8147233_0 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 468.0
REGS1_k127_8147233_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 382.0
REGS1_k127_8147233_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 328.0
REGS1_k127_8147233_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000832 209.0
REGS1_k127_8147233_4 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.0000000000000000000000000000000000000000000000000000000197 198.0
REGS1_k127_8147233_5 - - - - 0.00000000000000000000000000000001792 130.0
REGS1_k127_8165968_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 2.279e-194 615.0
REGS1_k127_8165968_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 505.0
REGS1_k127_8165968_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007045 279.0
REGS1_k127_8165968_3 CoA binding domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 277.0
REGS1_k127_8165968_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002482 252.0
REGS1_k127_8165968_5 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000008992 186.0
REGS1_k127_8177385_0 Sortilin, neurotensin receptor 3, - - - 0.0 1261.0
REGS1_k127_8177385_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 565.0
REGS1_k127_8177385_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 546.0
REGS1_k127_8177385_3 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000008463 168.0
REGS1_k127_8177385_4 radical SAM domain protein - - - 0.00000000000000000000000000006474 116.0
REGS1_k127_8177385_5 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000008732 101.0
REGS1_k127_8177385_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0003914 53.0
REGS1_k127_8191387_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.412e-195 620.0
REGS1_k127_8191387_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 493.0
REGS1_k127_8191387_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 443.0
REGS1_k127_8191387_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 417.0
REGS1_k127_8191387_4 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 369.0
REGS1_k127_8191387_5 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
REGS1_k127_8191387_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.0000000000000000000000000000000000000000000000002601 181.0
REGS1_k127_8219467_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 8.376e-318 979.0
REGS1_k127_8219467_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 416.0
REGS1_k127_8219467_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000003126 172.0
REGS1_k127_8219467_3 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000001247 102.0
REGS1_k127_8219467_4 PIN domain K07065 - - 0.00000000000006424 77.0
REGS1_k127_8219467_5 Transglutaminase-like superfamily - - - 0.00000001255 62.0
REGS1_k127_8219467_6 Transport permease protein K01992 - - 0.000004138 55.0
REGS1_k127_8224281_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 4.769e-229 718.0
REGS1_k127_8224281_1 AMP-binding enzyme C-terminal domain - - - 8.77e-198 630.0
REGS1_k127_8224281_2 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 391.0
REGS1_k127_8224281_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 331.0
REGS1_k127_8224281_4 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
REGS1_k127_8224281_5 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000811 216.0
REGS1_k127_8224281_6 Sporulation related domain - - - 0.000000000000000000000000000000000000000000564 165.0
REGS1_k127_8224281_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000007775 133.0
REGS1_k127_8224281_8 - - - - 0.00000000000000000000000000003689 121.0
REGS1_k127_8224281_9 PFAM Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000004861 68.0
REGS1_k127_8225629_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.881e-219 687.0
REGS1_k127_8225629_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 573.0
REGS1_k127_8225629_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003033 259.0
REGS1_k127_8225629_11 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000002809 252.0
REGS1_k127_8225629_12 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000007669 231.0
REGS1_k127_8225629_13 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000006884 216.0
REGS1_k127_8225629_14 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000002828 211.0
REGS1_k127_8225629_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000002646 180.0
REGS1_k127_8225629_17 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000006047 81.0
REGS1_k127_8225629_18 isomerase activity K01821 - 5.3.2.6 0.000006976 50.0
REGS1_k127_8225629_19 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0005464 46.0
REGS1_k127_8225629_2 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 556.0
REGS1_k127_8225629_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 475.0
REGS1_k127_8225629_4 Aminotransferase class-V K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 446.0
REGS1_k127_8225629_5 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 418.0
REGS1_k127_8225629_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 338.0
REGS1_k127_8225629_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 329.0
REGS1_k127_8225629_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 327.0
REGS1_k127_8225629_9 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 322.0
REGS1_k127_8240009_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 581.0
REGS1_k127_824625_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.942e-257 802.0
REGS1_k127_824625_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
REGS1_k127_824625_2 Mrr N-terminal domain - - - 0.00000000000001478 80.0
REGS1_k127_824625_3 - - - - 0.0000000000006405 74.0
REGS1_k127_824625_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000009159 60.0
REGS1_k127_8282749_0 Cytochrome c554 and c-prime - - - 0.0 1172.0
REGS1_k127_8282749_1 ASPIC and UnbV - - - 2.769e-247 772.0
REGS1_k127_8282749_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 542.0
REGS1_k127_8282749_3 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 444.0
REGS1_k127_8282749_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001899 257.0
REGS1_k127_8282749_5 TPR repeat - - - 0.00000000000001313 85.0
REGS1_k127_8292164_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000005885 141.0
REGS1_k127_8292164_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000003768 133.0
REGS1_k127_8292164_2 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000258 100.0
REGS1_k127_8292164_3 - - - - 0.000000000004961 69.0
REGS1_k127_8292164_4 Carboxymuconolactone decarboxylase family - - - 0.0000000000512 65.0
REGS1_k127_8303962_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.338e-201 635.0
REGS1_k127_8303962_1 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 513.0
REGS1_k127_8321740_0 Phage portal protein - - - 0.0000000000000000000000000000000000000000000000000000000003456 203.0
REGS1_k127_8321740_1 - - - - 0.000000000000000000000000000000000000000000000000001837 191.0
REGS1_k127_8321740_2 - - - - 0.000000000000000000000000000002037 121.0
REGS1_k127_8346168_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 451.0
REGS1_k127_8346168_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 361.0
REGS1_k127_8346999_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 456.0
REGS1_k127_8346999_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
REGS1_k127_8346999_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000619 177.0
REGS1_k127_8355_0 AcrB/AcrD/AcrF family - - - 0.0 1368.0
REGS1_k127_8355_1 GlcNAc-PI de-N-acetylase - - - 5.337e-235 756.0
REGS1_k127_8355_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001038 264.0
REGS1_k127_8355_11 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000241 252.0
REGS1_k127_8355_12 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001118 245.0
REGS1_k127_8355_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000871 216.0
REGS1_k127_8355_14 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000008109 119.0
REGS1_k127_8355_15 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000001993 109.0
REGS1_k127_8355_16 Protein of unknown function (DUF2892) - - - 0.000000000000000000003498 94.0
REGS1_k127_8355_17 - - - - 0.00000000000000001968 84.0
REGS1_k127_8355_18 OsmC-like protein - - - 0.000000000001033 71.0
REGS1_k127_8355_2 amino acid - - - 5.805e-199 631.0
REGS1_k127_8355_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 445.0
REGS1_k127_8355_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 448.0
REGS1_k127_8355_5 Belongs to the GSP D family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 451.0
REGS1_k127_8355_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 412.0
REGS1_k127_8355_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 314.0
REGS1_k127_8355_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 308.0
REGS1_k127_8355_9 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 302.0
REGS1_k127_8355624_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 471.0
REGS1_k127_8355624_1 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000005831 220.0
REGS1_k127_8364749_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1174.0
REGS1_k127_8364749_1 Participates in both transcription termination and antitermination K02600 - - 1.267e-230 724.0
REGS1_k127_8364749_10 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000000000000000001602 148.0
REGS1_k127_8364749_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000007638 136.0
REGS1_k127_8364749_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001642 59.0
REGS1_k127_8364749_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 589.0
REGS1_k127_8364749_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 469.0
REGS1_k127_8364749_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 456.0
REGS1_k127_8364749_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 436.0
REGS1_k127_8364749_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 396.0
REGS1_k127_8364749_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
REGS1_k127_8364749_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000000565 205.0
REGS1_k127_8364749_9 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000005778 169.0
REGS1_k127_8373144_0 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 304.0
REGS1_k127_8373144_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000122 277.0
REGS1_k127_8373144_2 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000002709 256.0
REGS1_k127_8373144_3 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000006194 204.0
REGS1_k127_8373144_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000175 195.0
REGS1_k127_8373144_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000158 178.0
REGS1_k127_8373144_6 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000003491 135.0
REGS1_k127_8409068_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 341.0
REGS1_k127_8409068_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001644 258.0
REGS1_k127_8409068_2 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000000000000000000000002061 198.0
REGS1_k127_8430786_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 382.0
REGS1_k127_8430786_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 337.0
REGS1_k127_8430786_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 329.0
REGS1_k127_8430786_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 290.0
REGS1_k127_8430786_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001417 270.0
REGS1_k127_8430786_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000003534 87.0
REGS1_k127_8435312_0 Alpha/beta hydrolase family - - - 5.714e-262 818.0
REGS1_k127_8435312_1 Aminotransferase class-III K00823 - 2.6.1.19 1.122e-228 717.0
REGS1_k127_8435312_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 315.0
REGS1_k127_8435312_11 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000005208 241.0
REGS1_k127_8435312_12 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000006602 186.0
REGS1_k127_8435312_13 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000002595 184.0
REGS1_k127_8435312_14 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000003779 147.0
REGS1_k127_8435312_15 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000001962 141.0
REGS1_k127_8435312_16 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000004316 137.0
REGS1_k127_8435312_17 GAF domain - - - 0.000000000000000000004906 109.0
REGS1_k127_8435312_18 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000005811 90.0
REGS1_k127_8435312_19 TIGRFAM TonB K03832 - - 0.000000000000001296 91.0
REGS1_k127_8435312_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 612.0
REGS1_k127_8435312_20 COG0457 FOG TPR repeat - - - 0.0000000000002921 83.0
REGS1_k127_8435312_22 phosphorelay signal transduction system - - - 0.000007021 59.0
REGS1_k127_8435312_23 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.0005671 53.0
REGS1_k127_8435312_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 595.0
REGS1_k127_8435312_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 525.0
REGS1_k127_8435312_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 488.0
REGS1_k127_8435312_6 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 449.0
REGS1_k127_8435312_7 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 458.0
REGS1_k127_8435312_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 415.0
REGS1_k127_8435312_9 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
REGS1_k127_8462789_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 378.0
REGS1_k127_8490357_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 298.0
REGS1_k127_8490357_1 Protein tyrosine kinase - - - 0.0000000002799 64.0
REGS1_k127_8529617_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 498.0
REGS1_k127_8529617_1 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 436.0
REGS1_k127_8529617_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 327.0
REGS1_k127_8529617_3 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000007937 189.0
REGS1_k127_8529617_4 Putative zinc-finger - - - 0.00000000000000000000000000000000002572 136.0
REGS1_k127_8529617_5 - - - - 0.000000000000000003109 89.0
REGS1_k127_8543425_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 496.0
REGS1_k127_8543425_1 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000000001372 245.0
REGS1_k127_8566905_0 TonB dependent receptor - - - 0.0 1034.0
REGS1_k127_8566905_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 524.0
REGS1_k127_8566905_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000001302 189.0
REGS1_k127_857165_0 PFAM Organic solvent tolerance protein K04744 - - 2.913e-270 857.0
REGS1_k127_857165_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 378.0
REGS1_k127_857165_2 - - - - 0.00000001764 61.0
REGS1_k127_857165_3 pfam rdd - - - 0.000001484 59.0
REGS1_k127_859996_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.086e-317 976.0
REGS1_k127_859996_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 404.0
REGS1_k127_859996_2 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 398.0
REGS1_k127_859996_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 299.0
REGS1_k127_859996_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006472 233.0
REGS1_k127_859996_5 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000003194 202.0
REGS1_k127_859996_6 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000000000000000000000006624 152.0
REGS1_k127_859996_8 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000007086 98.0
REGS1_k127_859996_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000001793 92.0
REGS1_k127_8603422_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 8.567e-247 770.0
REGS1_k127_8603422_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 2.951e-216 679.0
REGS1_k127_8603422_2 Sodium:solute symporter family - - - 4.251e-195 620.0
REGS1_k127_8603422_3 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 587.0
REGS1_k127_8603422_4 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 373.0
REGS1_k127_8603422_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 295.0
REGS1_k127_8603422_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002638 247.0
REGS1_k127_8603422_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000008063 215.0
REGS1_k127_8603422_8 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000004425 121.0
REGS1_k127_8603422_9 PFAM Septum formation initiator K05589 - - 0.00000000000000000006941 95.0
REGS1_k127_8623159_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.998e-233 728.0
REGS1_k127_8623159_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 426.0
REGS1_k127_8623159_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 345.0
REGS1_k127_8623159_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 317.0
REGS1_k127_8623159_4 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
REGS1_k127_8623159_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000007817 158.0
REGS1_k127_8623159_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000003595 56.0
REGS1_k127_8624832_0 Mu-like prophage FluMu protein gp28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 581.0
REGS1_k127_8624832_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 375.0
REGS1_k127_8624832_2 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
REGS1_k127_8682064_0 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 591.0
REGS1_k127_8682064_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 431.0
REGS1_k127_8682064_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 366.0
REGS1_k127_8682064_3 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006227 277.0
REGS1_k127_8682064_4 Cytochrome c - - - 0.0000000000000000000000000001623 121.0
REGS1_k127_8682064_5 integral membrane protein - - - 0.000000000000000000000000008933 115.0
REGS1_k127_8682064_6 Protein of unknown function (DUF3106) - - - 0.00000000000000000003414 99.0
REGS1_k127_8688632_0 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 535.0
REGS1_k127_8688632_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002413 282.0
REGS1_k127_8688632_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000005106 218.0
REGS1_k127_8688632_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000001486 195.0
REGS1_k127_8769172_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 569.0
REGS1_k127_8769172_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 367.0
REGS1_k127_8769172_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000007457 211.0
REGS1_k127_8769172_3 cellulase activity - - - 0.000000000000001364 90.0
REGS1_k127_8769172_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0002368 47.0
REGS1_k127_8787557_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 2.458e-246 783.0
REGS1_k127_8787557_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.566e-217 709.0
REGS1_k127_8787557_10 TPR repeat - - - 0.000000000000000000000000000000000000000000007123 179.0
REGS1_k127_8787557_11 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000004844 135.0
REGS1_k127_8787557_12 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.00000000000000000000000000001946 123.0
REGS1_k127_8787557_13 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000006813 113.0
REGS1_k127_8787557_15 - - - - 0.0000000000000000000005805 107.0
REGS1_k127_8787557_2 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 494.0
REGS1_k127_8787557_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 467.0
REGS1_k127_8787557_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 417.0
REGS1_k127_8787557_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 420.0
REGS1_k127_8787557_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 369.0
REGS1_k127_8787557_7 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002832 282.0
REGS1_k127_8787557_8 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000003334 234.0
REGS1_k127_8787557_9 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000001307 207.0
REGS1_k127_8794506_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1039.0
REGS1_k127_8794506_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 1.474e-239 755.0
REGS1_k127_8794506_10 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 392.0
REGS1_k127_8794506_11 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 381.0
REGS1_k127_8794506_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 365.0
REGS1_k127_8794506_13 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
REGS1_k127_8794506_14 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 357.0
REGS1_k127_8794506_15 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 345.0
REGS1_k127_8794506_16 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 332.0
REGS1_k127_8794506_17 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
REGS1_k127_8794506_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 302.0
REGS1_k127_8794506_19 SMART cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001289 277.0
REGS1_k127_8794506_2 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 1.94e-239 759.0
REGS1_k127_8794506_20 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000186 246.0
REGS1_k127_8794506_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000002091 229.0
REGS1_k127_8794506_22 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000007731 203.0
REGS1_k127_8794506_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001085 211.0
REGS1_k127_8794506_24 AI-2E family transporter - - - 0.000000000000000000000000000000000000000001505 167.0
REGS1_k127_8794506_25 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000000000000005498 162.0
REGS1_k127_8794506_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000001446 154.0
REGS1_k127_8794506_27 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000000000000000000000000000008588 139.0
REGS1_k127_8794506_28 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000008859 114.0
REGS1_k127_8794506_29 Heavy-metal resistance - - - 0.0000000000000000001008 96.0
REGS1_k127_8794506_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.443e-225 709.0
REGS1_k127_8794506_30 Heavy-metal resistance - - - 0.0000000000000001218 87.0
REGS1_k127_8794506_31 Antibiotic biosynthesis monooxygenase - - - 0.000000000001688 70.0
REGS1_k127_8794506_4 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 616.0
REGS1_k127_8794506_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 582.0
REGS1_k127_8794506_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 573.0
REGS1_k127_8794506_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 534.0
REGS1_k127_8794506_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 500.0
REGS1_k127_8794506_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 441.0
REGS1_k127_8842914_0 PFAM peptidase M13 K01415 - 3.4.24.71 6.773e-256 807.0
REGS1_k127_8842914_1 Peptidase family M49 - - - 2.319e-219 696.0
REGS1_k127_8842914_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 475.0
REGS1_k127_8842914_3 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 370.0
REGS1_k127_8842914_4 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 366.0
REGS1_k127_8842914_5 DinB family - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
REGS1_k127_8842914_6 extracellular matrix structural constituent - - - 0.0000000008183 68.0
REGS1_k127_886406_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 612.0
REGS1_k127_886406_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 457.0
REGS1_k127_886406_2 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 446.0
REGS1_k127_886406_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
REGS1_k127_886406_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 299.0
REGS1_k127_886406_5 DinB family - - - 0.000000000000000000000002355 111.0
REGS1_k127_886406_6 Regulatory protein, FmdB - - - 0.000000000000000000006305 98.0
REGS1_k127_8881540_0 GTP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 473.0
REGS1_k127_8881540_1 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000001536 243.0
REGS1_k127_89572_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 296.0
REGS1_k127_89572_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000005937 196.0
REGS1_k127_89572_2 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000001117 156.0
REGS1_k127_903001_0 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 432.0
REGS1_k127_903001_1 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000006031 159.0
REGS1_k127_903001_2 - - - - 0.00000000000000000000000000000000000000004954 158.0
REGS1_k127_903001_3 - - - - 0.000009283 51.0
REGS1_k127_9110101_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 564.0
REGS1_k127_9110101_1 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 512.0
REGS1_k127_9110101_10 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.00000000000000000000000000000003338 129.0
REGS1_k127_9110101_2 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 501.0
REGS1_k127_9110101_3 Organic Anion Transporter Polypeptide (OATP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 495.0
REGS1_k127_9110101_4 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 416.0
REGS1_k127_9110101_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 395.0
REGS1_k127_9110101_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000003232 221.0
REGS1_k127_9110101_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000004242 194.0
REGS1_k127_9110101_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000000000000000001095 193.0
REGS1_k127_9110101_9 - - - - 0.0000000000000000000000000000000008685 137.0
REGS1_k127_9115877_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 452.0
REGS1_k127_9115877_1 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 409.0
REGS1_k127_9115877_2 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 409.0
REGS1_k127_9115877_3 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 385.0
REGS1_k127_9115877_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 308.0
REGS1_k127_9115877_5 MarR family transcriptional K15973 - - 0.0000000000000000000000000000000000000005919 153.0
REGS1_k127_9115877_6 Regulatory protein, FmdB family - - - 0.0000000001802 63.0
REGS1_k127_9150515_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1497.0
REGS1_k127_9150515_1 PFAM peptidase - - - 1.818e-213 672.0
REGS1_k127_9150515_10 YtxH-like protein - - - 0.000000000000000000000000000007999 121.0
REGS1_k127_9150515_2 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 452.0
REGS1_k127_9150515_3 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 351.0
REGS1_k127_9150515_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001634 283.0
REGS1_k127_9150515_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007167 256.0
REGS1_k127_9150515_6 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
REGS1_k127_9150515_7 PFAM Colicin V production K03558 - - 0.00000000000000000000000000000000000000000000000001705 186.0
REGS1_k127_9150515_8 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000003082 145.0
REGS1_k127_9150515_9 - - - - 0.0000000000000000000000000000000004234 141.0
REGS1_k127_9168339_0 Tetratricopeptide repeats K12132 - 2.7.11.1 2.981e-267 850.0
REGS1_k127_9178335_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 571.0
REGS1_k127_9178335_1 cytochrome c nitrite reductase K15876 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
REGS1_k127_9178335_2 PhoQ Sensor K07640 - 2.7.13.3 0.000000000000000000000000000000187 125.0
REGS1_k127_953798_0 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 416.0
REGS1_k127_953798_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 334.0
REGS1_k127_953798_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
REGS1_k127_953798_3 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000001391 187.0
REGS1_k127_953798_4 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000005278 187.0
REGS1_k127_953798_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000006364 192.0
REGS1_k127_953798_6 Cupin domain - - - 0.000000000000000000000000000000000000000000000005959 175.0