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Overview

ID MAG03323
Name REGS2_bin.1
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Terriglobales
Family JAHFUA01
Genus
Species
Assembly information
Completeness (%) 76.58
Contamination (%) 2.81
GC content (%) 66.0
N50 (bp) 4,410
Genome size (bp) 2,056,753

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2016

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1002287_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 7.391e-299 933.0
REGS2_k127_1002287_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 534.0
REGS2_k127_1002287_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 527.0
REGS2_k127_1002287_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 494.0
REGS2_k127_1002287_4 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 314.0
REGS2_k127_1006834_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 607.0
REGS2_k127_1006834_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000679 139.0
REGS2_k127_1009402_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 0.0 996.0
REGS2_k127_1009402_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 535.0
REGS2_k127_1009402_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000218 78.0
REGS2_k127_1021052_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.905e-217 684.0
REGS2_k127_1021052_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 387.0
REGS2_k127_1021052_2 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000009314 242.0
REGS2_k127_1021052_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001087 224.0
REGS2_k127_1041209_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 308.0
REGS2_k127_1041209_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
REGS2_k127_1076276_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000001279 190.0
REGS2_k127_1076276_1 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000001082 78.0
REGS2_k127_1092769_0 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 8.303e-271 839.0
REGS2_k127_1096380_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1279.0
REGS2_k127_1096380_1 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 366.0
REGS2_k127_1096380_2 peroxiredoxin activity K03386 - 1.11.1.15 0.000000000000000000000000000000000000000005514 156.0
REGS2_k127_1096380_3 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.00000000002586 66.0
REGS2_k127_1097608_0 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 361.0
REGS2_k127_1097608_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000002611 240.0
REGS2_k127_109804_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000004231 250.0
REGS2_k127_1098856_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 9.058e-232 727.0
REGS2_k127_1098856_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000002026 106.0
REGS2_k127_1103860_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 570.0
REGS2_k127_1103860_1 - - - - 0.000000003131 64.0
REGS2_k127_1125437_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 326.0
REGS2_k127_1125437_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000002024 216.0
REGS2_k127_1125437_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000001815 201.0
REGS2_k127_1125437_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000528 197.0
REGS2_k127_1125437_4 biotin carboxylase activity K01961 - 6.3.4.14,6.4.1.2 0.000005166 48.0
REGS2_k127_112670_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 346.0
REGS2_k127_112670_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 338.0
REGS2_k127_112670_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000174 64.0
REGS2_k127_1135019_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1216.0
REGS2_k127_1135019_1 Prokaryotic cytochrome b561 - - - 4.517e-239 760.0
REGS2_k127_1135019_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 4.961e-217 680.0
REGS2_k127_1135019_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 600.0
REGS2_k127_1135019_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 602.0
REGS2_k127_1135019_5 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 455.0
REGS2_k127_1135019_6 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
REGS2_k127_1135019_7 Domain of Unknown function (DUF542) K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008406 268.0
REGS2_k127_1135019_8 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000005465 132.0
REGS2_k127_1135019_9 response regulator, receiver - - - 0.000000000000000000000000002472 115.0
REGS2_k127_113963_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.707e-263 828.0
REGS2_k127_113963_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 382.0
REGS2_k127_1153656_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 556.0
REGS2_k127_1153656_1 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 531.0
REGS2_k127_1161665_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000001449 193.0
REGS2_k127_1161665_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000009484 194.0
REGS2_k127_1161665_2 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.0000000000000000000004522 98.0
REGS2_k127_1205145_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 484.0
REGS2_k127_1205145_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 457.0
REGS2_k127_1205145_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 304.0
REGS2_k127_1205145_3 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
REGS2_k127_1261139_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.003e-262 817.0
REGS2_k127_1261903_0 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 389.0
REGS2_k127_1266086_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.195e-233 732.0
REGS2_k127_1275874_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 582.0
REGS2_k127_1275874_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 423.0
REGS2_k127_1275874_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000656 274.0
REGS2_k127_1275874_3 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000003389 131.0
REGS2_k127_1284926_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000001159 153.0
REGS2_k127_1284926_1 - - - - 0.00000000000000000004554 92.0
REGS2_k127_1284926_2 Lysin motif K08307 - - 0.000000000000000002486 88.0
REGS2_k127_1289118_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.638e-206 648.0
REGS2_k127_1289118_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000457 72.0
REGS2_k127_1334504_0 PFAM Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 332.0
REGS2_k127_1334504_1 IMG reference gene - - - 0.0000000000000000000000001448 109.0
REGS2_k127_1337610_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.288e-207 651.0
REGS2_k127_1337610_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 538.0
REGS2_k127_1337610_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 512.0
REGS2_k127_1337610_3 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000002465 132.0
REGS2_k127_1347864_0 Belongs to the peptidase M48B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 543.0
REGS2_k127_1347864_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 329.0
REGS2_k127_1347864_2 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000000000000000000000000000004654 200.0
REGS2_k127_1347864_4 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.000000477 56.0
REGS2_k127_1348860_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 2.75e-310 956.0
REGS2_k127_1348860_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 552.0
REGS2_k127_1348860_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 514.0
REGS2_k127_1348860_3 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 493.0
REGS2_k127_1348860_4 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 430.0
REGS2_k127_1348860_5 - - - - 0.000000002576 62.0
REGS2_k127_1352903_0 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 374.0
REGS2_k127_1352903_1 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000000003233 210.0
REGS2_k127_1352903_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001189 206.0
REGS2_k127_1352903_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000001049 190.0
REGS2_k127_1352903_4 TIGRFAM TonB K03832 - - 0.0000000000000000000000000000000001137 134.0
REGS2_k127_1356930_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 419.0
REGS2_k127_1356930_1 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000000002147 179.0
REGS2_k127_1356944_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 4.06e-204 646.0
REGS2_k127_1356944_1 belongs to the aldehyde dehydrogenase family K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 471.0
REGS2_k127_1356944_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000003346 217.0
REGS2_k127_1356944_3 BMC K04027 - - 0.00000000000000000000000000000000001 139.0
REGS2_k127_1356944_4 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000000116 134.0
REGS2_k127_1360328_0 dead deah K03724 - - 4.011e-272 846.0
REGS2_k127_1360328_1 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000001743 164.0
REGS2_k127_1375372_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.812e-298 921.0
REGS2_k127_1375372_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 568.0
REGS2_k127_1375372_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 448.0
REGS2_k127_1375372_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 411.0
REGS2_k127_1375372_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 403.0
REGS2_k127_1375372_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007809 259.0
REGS2_k127_1375372_7 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000004096 193.0
REGS2_k127_1391380_0 Elongation factor G, domain IV K02355 - - 0.0 1093.0
REGS2_k127_1391380_1 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 260.0
REGS2_k127_1391380_2 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000002231 137.0
REGS2_k127_1391380_3 Bacterial regulatory proteins, tetR family - - - 0.000000001966 70.0
REGS2_k127_1394692_0 Radical SAM superfamily K06937 - - 2.396e-271 845.0
REGS2_k127_1394692_2 Type II transport protein GspH K08084 - - 0.000000686 59.0
REGS2_k127_1430128_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.667e-231 721.0
REGS2_k127_1430128_1 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 312.0
REGS2_k127_1430128_2 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 263.0
REGS2_k127_1436242_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.194e-267 828.0
REGS2_k127_1436242_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 417.0
REGS2_k127_1441337_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 386.0
REGS2_k127_1441337_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000007684 270.0
REGS2_k127_1445519_0 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 9.325e-251 786.0
REGS2_k127_1446515_0 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 375.0
REGS2_k127_1446515_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 370.0
REGS2_k127_1446515_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 319.0
REGS2_k127_1448199_0 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 405.0
REGS2_k127_1448199_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000001182 146.0
REGS2_k127_1448199_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000005986 92.0
REGS2_k127_1449051_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 458.0
REGS2_k127_1449051_1 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000001067 200.0
REGS2_k127_145638_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1031.0
REGS2_k127_145638_1 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 514.0
REGS2_k127_145638_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 460.0
REGS2_k127_145638_3 PASTA domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000787 232.0
REGS2_k127_1460789_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 484.0
REGS2_k127_1460789_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000003132 161.0
REGS2_k127_1460789_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000005009 139.0
REGS2_k127_1479629_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 593.0
REGS2_k127_1479629_1 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000005534 156.0
REGS2_k127_1480925_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 576.0
REGS2_k127_1480925_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 463.0
REGS2_k127_1480925_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 463.0
REGS2_k127_1480925_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 352.0
REGS2_k127_1480925_4 Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 297.0
REGS2_k127_1480925_5 - - - - 0.0000000000000000000000000000000000000000000000000000825 193.0
REGS2_k127_1480925_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000007384 177.0
REGS2_k127_1480925_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000002087 148.0
REGS2_k127_1480925_8 FHA domain - - - 0.000000005083 69.0
REGS2_k127_1492064_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.53e-210 674.0
REGS2_k127_1492064_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 560.0
REGS2_k127_1492064_2 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 440.0
REGS2_k127_1492064_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 364.0
REGS2_k127_1492064_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 254.0
REGS2_k127_1492064_5 - - - - 0.000000000000000000000000000002242 129.0
REGS2_k127_1492064_6 - - - - 0.000000000000000000000002015 111.0
REGS2_k127_1538815_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 524.0
REGS2_k127_1538815_1 cyclic nucleotide binding K10914 - - 0.00000000000001383 83.0
REGS2_k127_1542225_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.627e-237 745.0
REGS2_k127_1542626_0 Peptidase family M49 - - - 1.343e-226 719.0
REGS2_k127_1542626_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 424.0
REGS2_k127_1542626_2 Peptidase S9 prolyl oligopeptidase active site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 321.0
REGS2_k127_1542626_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000001932 223.0
REGS2_k127_1543127_0 Abhydrolase domain containing 18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 444.0
REGS2_k127_1543127_1 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 369.0
REGS2_k127_1543127_2 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000003671 156.0
REGS2_k127_1545819_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 8.521e-227 728.0
REGS2_k127_1545819_1 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000002895 192.0
REGS2_k127_156085_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 9.511e-229 738.0
REGS2_k127_156085_1 Peptidase S46 - - - 1.367e-219 703.0
REGS2_k127_156085_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 604.0
REGS2_k127_156085_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 338.0
REGS2_k127_156085_4 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 293.0
REGS2_k127_156085_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 283.0
REGS2_k127_156085_6 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000008395 255.0
REGS2_k127_156085_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000006243 185.0
REGS2_k127_156085_8 Vitamin K epoxide reductase family - - - 0.00000000000000000002585 92.0
REGS2_k127_156085_9 Vitamin K epoxide reductase - - - 0.000000000001011 74.0
REGS2_k127_1569594_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 329.0
REGS2_k127_1569594_1 transposase activity K07483 - - 0.000000000000001906 79.0
REGS2_k127_1595120_0 Radical SAM superfamily K06937 - - 2.225e-311 960.0
REGS2_k127_1595120_1 Carboxypeptidase regulatory-like domain - - - 0.00005644 45.0
REGS2_k127_1602428_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.991e-249 777.0
REGS2_k127_1604199_0 PFAM Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 526.0
REGS2_k127_1604199_1 synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 301.0
REGS2_k127_1604199_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001248 264.0
REGS2_k127_1604199_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000009537 187.0
REGS2_k127_1604199_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000001437 105.0
REGS2_k127_162702_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.647e-208 649.0
REGS2_k127_1639217_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 8.551e-218 680.0
REGS2_k127_1639217_1 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 409.0
REGS2_k127_1639217_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 355.0
REGS2_k127_1653872_0 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 448.0
REGS2_k127_1653872_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 358.0
REGS2_k127_1653872_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
REGS2_k127_1653872_3 PFAM Colicin V production K03558 - - 0.000000000000000000000000000000000000000000000000218 182.0
REGS2_k127_1653872_4 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000007694 140.0
REGS2_k127_1662652_0 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 597.0
REGS2_k127_1662652_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 459.0
REGS2_k127_1662652_2 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 317.0
REGS2_k127_1662652_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 267.0
REGS2_k127_1662652_4 - - - - 0.00000000000000000000000000000000000000000000000000000004427 203.0
REGS2_k127_1662652_5 Putative zinc-finger - - - 0.000000000000000000000000000000001618 130.0
REGS2_k127_1662652_6 nuclear chromosome segregation - - - 0.000000000000000000000003565 113.0
REGS2_k127_1662652_7 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000872 90.0
REGS2_k127_1662652_8 - - - - 0.0000000001109 67.0
REGS2_k127_1670148_0 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 391.0
REGS2_k127_1686225_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002445 263.0
REGS2_k127_1686225_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001863 245.0
REGS2_k127_1686225_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002876 208.0
REGS2_k127_1686225_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000001197 83.0
REGS2_k127_171899_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.27e-227 707.0
REGS2_k127_171899_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000005337 151.0
REGS2_k127_1728163_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 462.0
REGS2_k127_1728163_1 Periplasmic or secreted lipoprotein - - - 0.00000000002229 73.0
REGS2_k127_1728163_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00008558 47.0
REGS2_k127_173385_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 380.0
REGS2_k127_173385_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 377.0
REGS2_k127_1769938_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 607.0
REGS2_k127_1769938_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000001959 194.0
REGS2_k127_1772805_0 PFAM Cytochrome c assembly protein K02198 - - 8.754e-210 658.0
REGS2_k127_1772805_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000002522 238.0
REGS2_k127_1772805_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000003285 120.0
REGS2_k127_1772805_3 PFAM response regulator receiver - - - 0.0000000000000000000000003887 110.0
REGS2_k127_1772805_4 Protein of unknown function (DUF2934) - - - 0.000004537 50.0
REGS2_k127_1777467_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 505.0
REGS2_k127_1777467_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000001632 192.0
REGS2_k127_1777467_2 - - - - 0.00000000000000000000000000000000000002353 146.0
REGS2_k127_1777467_3 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000005508 89.0
REGS2_k127_1836848_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.546e-196 629.0
REGS2_k127_1836848_1 R3H domain K06346 - - 0.000000000000000000000000000000000000000000000003457 181.0
REGS2_k127_1836848_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000002946 116.0
REGS2_k127_1836848_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000001573 107.0
REGS2_k127_1863578_0 Participates in both transcription termination and antitermination K02600 - - 1.368e-207 654.0
REGS2_k127_1863578_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000002352 204.0
REGS2_k127_1871676_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 527.0
REGS2_k127_1871676_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 447.0
REGS2_k127_1871676_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 329.0
REGS2_k127_1871676_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 307.0
REGS2_k127_1871676_4 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000000000003893 149.0
REGS2_k127_1871676_5 RNA recognition motif - - - 0.000000000000000000000000000000002157 132.0
REGS2_k127_1871676_6 Belongs to the HesB IscA family - - - 0.000000000000000000007456 93.0
REGS2_k127_1871676_7 - - - - 0.00000000000000000001689 93.0
REGS2_k127_1871676_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000004959 61.0
REGS2_k127_187557_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 326.0
REGS2_k127_187557_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
REGS2_k127_187557_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000008442 177.0
REGS2_k127_1954282_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.703e-250 815.0
REGS2_k127_1954282_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 5.266e-196 655.0
REGS2_k127_1956720_0 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 496.0
REGS2_k127_1956720_1 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 331.0
REGS2_k127_1956720_2 ABC transporter K02003 - - 0.000000000000000000000002737 105.0
REGS2_k127_1961070_0 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 370.0
REGS2_k127_1961070_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 323.0
REGS2_k127_1961070_2 cyclic nucleotide binding K01420,K21556,K21562 - - 0.000000000000000000000000000000000005721 143.0
REGS2_k127_1961070_4 phosphorelay signal transduction system - - - 0.0000000000000000000000009987 115.0
REGS2_k127_1961070_5 COG2199 FOG GGDEF domain - - - 0.000000001279 67.0
REGS2_k127_1970672_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 578.0
REGS2_k127_1970672_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 294.0
REGS2_k127_1970672_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000746 142.0
REGS2_k127_1970672_4 - - - - 0.000000000000000000000000362 105.0
REGS2_k127_1977946_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 8.146e-279 865.0
REGS2_k127_1977946_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 562.0
REGS2_k127_1977946_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 425.0
REGS2_k127_1977946_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 351.0
REGS2_k127_1977946_4 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 331.0
REGS2_k127_1977946_5 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 329.0
REGS2_k127_1977946_6 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000228 185.0
REGS2_k127_1977946_7 - - - - 0.0000000004583 68.0
REGS2_k127_1983065_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1268.0
REGS2_k127_1983065_1 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 303.0
REGS2_k127_201236_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.808e-229 716.0
REGS2_k127_201236_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 389.0
REGS2_k127_201236_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 291.0
REGS2_k127_201236_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005004 272.0
REGS2_k127_2033502_0 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 430.0
REGS2_k127_2033502_2 HD domain - - - 0.000000000000000003572 91.0
REGS2_k127_2033502_3 Protein of unknown function, DUF393 - - - 0.000000000009046 70.0
REGS2_k127_2046232_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.975e-197 618.0
REGS2_k127_2046232_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 381.0
REGS2_k127_2046232_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000006137 154.0
REGS2_k127_2046232_3 belongs to the Fur family K03711,K09823,K09825 - - 0.000000000000000000000000000000000000001159 153.0
REGS2_k127_2055149_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 2.706e-269 842.0
REGS2_k127_2055149_1 Tetratricopeptide repeat - - - 7.191e-252 812.0
REGS2_k127_2055149_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 405.0
REGS2_k127_2055149_3 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000003937 194.0
REGS2_k127_2055149_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000009574 124.0
REGS2_k127_2055149_5 - - - - 0.00000000000000000001557 97.0
REGS2_k127_2055149_6 - - - - 0.0000000001514 64.0
REGS2_k127_2055625_0 Arginosuccinate synthase K01940 - 6.3.4.5 2.171e-210 659.0
REGS2_k127_2055625_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 549.0
REGS2_k127_2055625_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009279 442.0
REGS2_k127_2055625_3 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 399.0
REGS2_k127_2055625_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 387.0
REGS2_k127_2055625_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 364.0
REGS2_k127_2055625_6 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000002237 205.0
REGS2_k127_2056044_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 520.0
REGS2_k127_2056044_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 511.0
REGS2_k127_2056044_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 369.0
REGS2_k127_2056044_3 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 314.0
REGS2_k127_2056044_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000008466 189.0
REGS2_k127_2084934_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 589.0
REGS2_k127_2084934_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 296.0
REGS2_k127_2084934_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000007441 180.0
REGS2_k127_2142776_0 ABC transporter K11085 - - 9.898e-268 836.0
REGS2_k127_214871_0 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009416 277.0
REGS2_k127_214871_1 GtrA-like protein - - - 0.00000000000000000000000000002515 131.0
REGS2_k127_214871_2 PFAM Aminotransferase, class I K10907 - - 0.000000000000000000000000001969 115.0
REGS2_k127_214871_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000006484 77.0
REGS2_k127_2175192_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 324.0
REGS2_k127_2175192_1 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000000000001887 156.0
REGS2_k127_2175192_2 Bacterial Ig-like domain 2 - - - 0.00000000000000000000000000000000159 137.0
REGS2_k127_2175192_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000004478 63.0
REGS2_k127_2175192_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000003988 61.0
REGS2_k127_2180532_0 Tetratricopeptide repeat - - - 6.347e-222 703.0
REGS2_k127_2180532_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 434.0
REGS2_k127_2180532_2 BioY family K03523 - - 0.000000000000000000000000000000000000009714 153.0
REGS2_k127_2180532_5 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000002398 64.0
REGS2_k127_2186150_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 458.0
REGS2_k127_2186150_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 345.0
REGS2_k127_2186150_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000836 151.0
REGS2_k127_219716_0 Histidine kinase - - - 4.771e-230 721.0
REGS2_k127_2229440_0 Histidine kinase A domain protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 260.0
REGS2_k127_2229440_1 histidine kinase A domain protein K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000006342 233.0
REGS2_k127_22342_0 PAS domain - - - 7.535e-230 727.0
REGS2_k127_22342_1 Sigma-54 interaction domain - - - 7.127e-225 706.0
REGS2_k127_22342_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 352.0
REGS2_k127_22342_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 334.0
REGS2_k127_22342_4 - - - - 0.000000000000171 78.0
REGS2_k127_2238319_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 358.0
REGS2_k127_2238319_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 349.0
REGS2_k127_2241306_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 8.933e-257 811.0
REGS2_k127_2241306_1 virulence factor MVIN family protein K03980 - - 2.905e-208 662.0
REGS2_k127_2241306_2 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000001582 211.0
REGS2_k127_2241306_3 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase K10914 - - 0.0000000711 58.0
REGS2_k127_2241306_4 - - - - 0.0000008616 54.0
REGS2_k127_2279554_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1274.0
REGS2_k127_2285395_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 562.0
REGS2_k127_2285395_1 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 352.0
REGS2_k127_2302620_0 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 408.0
REGS2_k127_2302620_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 330.0
REGS2_k127_233983_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009311 276.0
REGS2_k127_233983_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000002682 239.0
REGS2_k127_233983_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000148 148.0
REGS2_k127_233983_3 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000003413 110.0
REGS2_k127_2350187_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 503.0
REGS2_k127_2350187_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
REGS2_k127_2357220_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 405.0
REGS2_k127_2357220_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 381.0
REGS2_k127_2357220_2 Dehydrogenase E1 component K00167,K11381,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000002069 237.0
REGS2_k127_2357220_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000005005 146.0
REGS2_k127_2357220_4 - - - - 0.000000003277 69.0
REGS2_k127_237282_0 Pyridoxal-dependent decarboxylase conserved domain - - - 1.351e-211 666.0
REGS2_k127_237282_1 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000372 216.0
REGS2_k127_238328_0 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 529.0
REGS2_k127_238328_1 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003298 253.0
REGS2_k127_238328_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000002968 177.0
REGS2_k127_238328_3 - - - - 0.000005825 50.0
REGS2_k127_2397392_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 327.0
REGS2_k127_2397392_1 FeS assembly protein IscX - - - 0.00000000000000000000000002076 111.0
REGS2_k127_2397392_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000006286 102.0
REGS2_k127_2397392_3 Aminotransferase class-III K00823 - 2.6.1.19 0.00000000000000000000002128 101.0
REGS2_k127_2418724_0 Glutaryl-7-ACA acylase K06978 - - 2.117e-320 989.0
REGS2_k127_2418724_1 Peptidase family M1 domain - - - 4.616e-232 744.0
REGS2_k127_2418724_2 peptidyl-tyrosine sulfation - - - 0.00001734 49.0
REGS2_k127_2449129_0 PFAM oxidoreductase domain protein - - - 3.459e-217 684.0
REGS2_k127_2459280_0 Type II/IV secretion system protein K02669 - - 5.469e-213 666.0
REGS2_k127_2459280_1 DinB family - - - 0.000000000000000000000000000000000000000000000001325 179.0
REGS2_k127_247103_0 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 394.0
REGS2_k127_247103_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 370.0
REGS2_k127_247103_2 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 356.0
REGS2_k127_247103_3 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 337.0
REGS2_k127_247103_4 photosynthesis - - - 0.000000000000000000000000000000000000000000000002279 185.0
REGS2_k127_247103_5 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000000001087 132.0
REGS2_k127_247103_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000008185 66.0
REGS2_k127_247103_7 COG0500 SAM-dependent methyltransferases - - - 0.0000002703 55.0
REGS2_k127_2481031_0 PFAM NLP P60 protein K21471 - - 0.00000000000000000000000000000000000000000000000000000003508 212.0
REGS2_k127_2481031_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.00000000000000000000001595 100.0
REGS2_k127_2507392_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 439.0
REGS2_k127_2507392_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
REGS2_k127_2508717_0 Elements of external origin - - - 5.421e-208 654.0
REGS2_k127_2510263_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 533.0
REGS2_k127_2510263_2 - - - - 0.00005303 47.0
REGS2_k127_2521520_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 7.362e-234 726.0
REGS2_k127_2521520_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 385.0
REGS2_k127_2521520_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002282 263.0
REGS2_k127_2521520_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000001466 179.0
REGS2_k127_2521520_4 Ribosomal protein L33 K02913 - - 0.000000000000000000002581 93.0
REGS2_k127_2521520_6 - - - - 0.0005067 45.0
REGS2_k127_2522572_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 551.0
REGS2_k127_2522572_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 547.0
REGS2_k127_2522572_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 336.0
REGS2_k127_2522572_3 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 300.0
REGS2_k127_2522572_4 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000001733 157.0
REGS2_k127_2522572_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000009578 55.0
REGS2_k127_2529042_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 329.0
REGS2_k127_2529042_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001828 190.0
REGS2_k127_2534754_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 569.0
REGS2_k127_2534754_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
REGS2_k127_2534754_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
REGS2_k127_2534754_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000827 189.0
REGS2_k127_2534754_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000271 172.0
REGS2_k127_254167_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 3.621e-242 784.0
REGS2_k127_254167_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 428.0
REGS2_k127_2547633_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 428.0
REGS2_k127_2547633_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000189 257.0
REGS2_k127_2556637_0 May be involved in recombinational repair of damaged DNA K03631 - - 6.232e-231 730.0
REGS2_k127_2556637_1 WD40-like Beta Propeller K03641 - - 2.237e-201 635.0
REGS2_k127_2556637_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 316.0
REGS2_k127_2556637_3 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 308.0
REGS2_k127_2556637_4 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000001223 229.0
REGS2_k127_2556637_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000005709 197.0
REGS2_k127_2563999_0 Ftsk_gamma K03466 - - 0.0 1044.0
REGS2_k127_2563999_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 458.0
REGS2_k127_2563999_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 392.0
REGS2_k127_2563999_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 311.0
REGS2_k127_2563999_4 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000001303 173.0
REGS2_k127_2563999_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000009286 83.0
REGS2_k127_2586809_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 1.019e-194 616.0
REGS2_k127_2586809_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 494.0
REGS2_k127_2586809_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000001638 139.0
REGS2_k127_2596918_0 ATPase BadF BadG BcrA BcrD type - - - 5.644e-267 854.0
REGS2_k127_2596918_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 426.0
REGS2_k127_2596918_2 TIGRFAM Transcriptional regulator, Rrf2 - - - 0.000000000000000000000006605 106.0
REGS2_k127_2602801_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1301.0
REGS2_k127_2602801_1 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 504.0
REGS2_k127_2609516_0 Belongs to the RtcB family K14415 - 6.5.1.3 4.939e-212 671.0
REGS2_k127_2609516_1 GYD domain - - - 0.0000000000000000000000000000000000000001689 161.0
REGS2_k127_2609516_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000008251 115.0
REGS2_k127_2651903_0 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 398.0
REGS2_k127_2651903_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002785 245.0
REGS2_k127_2651903_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006842 240.0
REGS2_k127_2651903_3 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000000004219 174.0
REGS2_k127_2675798_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1015.0
REGS2_k127_2684446_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 529.0
REGS2_k127_2684446_1 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000000000000000000000007293 152.0
REGS2_k127_2708581_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 365.0
REGS2_k127_2708581_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000004074 179.0
REGS2_k127_2708581_2 phosphorelay signal transduction system - - - 0.000000000002096 78.0
REGS2_k127_2722694_0 PFAM Organic solvent tolerance protein K04744 - - 3.782e-269 853.0
REGS2_k127_2722694_1 Peptidase family M13 K01415,K07386 - 3.4.24.71 1.668e-230 720.0
REGS2_k127_2722694_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000006168 241.0
REGS2_k127_2722694_3 pfam rdd - - - 0.00000000000000000000000000000001966 139.0
REGS2_k127_2764243_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 484.0
REGS2_k127_2764243_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 407.0
REGS2_k127_2764243_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 370.0
REGS2_k127_2764243_3 TOBE domain K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 331.0
REGS2_k127_2764243_4 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
REGS2_k127_2764243_5 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001655 287.0
REGS2_k127_2764243_6 Disulphide isomerase - - - 0.0000000000000000000000000000000000000000000000000004086 191.0
REGS2_k127_2764243_7 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000959 67.0
REGS2_k127_2765234_0 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 613.0
REGS2_k127_2765234_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 331.0
REGS2_k127_2765234_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000002331 262.0
REGS2_k127_2765234_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000009859 253.0
REGS2_k127_2765234_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000934 149.0
REGS2_k127_2765234_5 Tetratricopeptide repeat - - - 0.0000000000000002721 81.0
REGS2_k127_2765946_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 362.0
REGS2_k127_2765946_1 heme a metabolic process K02259,K03110 - - 0.000000000000000000000000000000000000000002894 166.0
REGS2_k127_2765946_2 PFAM ABC transporter K06158 - - 0.0000000008166 61.0
REGS2_k127_2769830_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 584.0
REGS2_k127_2769830_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009744 241.0
REGS2_k127_2769830_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000008947 183.0
REGS2_k127_2769830_3 acetyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.0000000004449 60.0
REGS2_k127_2769830_4 transporter antisigma-factor antagonist STAS K04749 - - 0.0002481 49.0
REGS2_k127_2781113_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 9.303e-197 618.0
REGS2_k127_2781113_1 Protein of unknown function (DUF962) - - - 0.00000377 49.0
REGS2_k127_2791380_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 501.0
REGS2_k127_2791380_1 radical SAM domain protein K22318 - - 0.00000000000000000000000000000008711 126.0
REGS2_k127_2794195_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 409.0
REGS2_k127_2794746_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 587.0
REGS2_k127_2794746_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008713 249.0
REGS2_k127_2794746_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000001755 164.0
REGS2_k127_2794746_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000002739 59.0
REGS2_k127_2806641_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 5.495e-275 853.0
REGS2_k127_281044_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 321.0
REGS2_k127_281044_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 302.0
REGS2_k127_2816556_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.41e-319 984.0
REGS2_k127_2816556_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 587.0
REGS2_k127_2816556_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 315.0
REGS2_k127_2816556_3 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000001661 237.0
REGS2_k127_2816556_4 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
REGS2_k127_2845696_0 PFAM Integrase catalytic - - - 6.122e-195 621.0
REGS2_k127_2863170_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 501.0
REGS2_k127_2863170_1 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 424.0
REGS2_k127_2863170_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 390.0
REGS2_k127_2863170_3 Major facilitator Superfamily K08152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009223 279.0
REGS2_k127_2863170_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000004456 171.0
REGS2_k127_2880312_0 PFAM Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000001514 166.0
REGS2_k127_2880312_1 Transposase IS200 like - - - 0.00000000000000000000000000000002905 130.0
REGS2_k127_2890494_0 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 446.0
REGS2_k127_2890494_1 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000007227 206.0
REGS2_k127_2890494_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000009982 162.0
REGS2_k127_2898774_0 Elongator protein 3, MiaB family, Radical SAM - - - 2.251e-205 643.0
REGS2_k127_2898774_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 472.0
REGS2_k127_2898774_2 Asparaginase K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 477.0
REGS2_k127_2898774_3 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 363.0
REGS2_k127_2898774_4 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 279.0
REGS2_k127_2898774_5 Cold shock protein domain K03704 - - 0.00000000000000000000000008011 109.0
REGS2_k127_2898774_6 Chlorite dismutase - - - 0.000000000000000000000001739 106.0
REGS2_k127_2898774_7 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000008516 100.0
REGS2_k127_2898774_8 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000007863 65.0
REGS2_k127_2915760_0 - - - - 2.944e-230 716.0
REGS2_k127_2915760_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 482.0
REGS2_k127_2915760_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 404.0
REGS2_k127_2915760_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004726 256.0
REGS2_k127_2915760_4 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000003404 218.0
REGS2_k127_2930237_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 7.456e-198 623.0
REGS2_k127_2933954_0 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 447.0
REGS2_k127_2933954_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 426.0
REGS2_k127_2933954_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 331.0
REGS2_k127_2933954_3 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004615 259.0
REGS2_k127_2933954_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000001052 214.0
REGS2_k127_2933954_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000001201 197.0
REGS2_k127_2933954_6 Likely ribonuclease with RNase H fold. K07447 - - 0.0000000000000000000000000000000000000000000001946 172.0
REGS2_k127_2942599_0 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 370.0
REGS2_k127_2942599_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 348.0
REGS2_k127_2942599_2 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.0000000000000000003644 89.0
REGS2_k127_295310_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 564.0
REGS2_k127_295310_1 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000007276 196.0
REGS2_k127_295310_2 GAF domain - - - 0.00000000004039 65.0
REGS2_k127_2974618_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1082.0
REGS2_k127_2974618_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 558.0
REGS2_k127_2974618_2 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 568.0
REGS2_k127_2974618_3 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 516.0
REGS2_k127_2974618_4 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000001671 215.0
REGS2_k127_2974618_5 - - - - 0.00000000000000000000000000000000000000000000003736 174.0
REGS2_k127_2974618_6 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000178 111.0
REGS2_k127_2984768_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 305.0
REGS2_k127_3001642_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 554.0
REGS2_k127_3001642_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002781 290.0
REGS2_k127_3001642_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001987 200.0
REGS2_k127_3001642_3 - - - - 0.000000000000000000000003263 104.0
REGS2_k127_3001642_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001311 80.0
REGS2_k127_3028081_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000009413 104.0
REGS2_k127_3028081_1 Peptidylprolyl isomerase K01802 - 5.2.1.8 0.000000004395 68.0
REGS2_k127_3075471_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.546e-260 809.0
REGS2_k127_3075471_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 409.0
REGS2_k127_3075471_2 DUF218 domain - - - 0.000000000000000000000000000002808 130.0
REGS2_k127_310246_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 545.0
REGS2_k127_310246_1 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 354.0
REGS2_k127_310246_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000002033 127.0
REGS2_k127_3110531_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 338.0
REGS2_k127_3110531_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001819 248.0
REGS2_k127_3123628_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 430.0
REGS2_k127_3123628_1 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000001045 192.0
REGS2_k127_3123628_2 ABC transporter K02003 - - 0.00002196 47.0
REGS2_k127_3129851_0 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 516.0
REGS2_k127_3129851_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 450.0
REGS2_k127_3129851_2 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 314.0
REGS2_k127_3129851_3 - - - - 0.00000000000000000000000000000000000008184 153.0
REGS2_k127_3144289_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.006e-277 868.0
REGS2_k127_3144289_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 504.0
REGS2_k127_3144289_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.000000000000000000000000000000000000000000000000000000000003654 220.0
REGS2_k127_3144289_3 GGDEF domain - - - 0.0000006231 62.0
REGS2_k127_3151220_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000006469 194.0
REGS2_k127_3151220_1 carbon utilization K02664,K02665,K12280 - - 0.00000000000000000000000000000000000000000000000000009704 193.0
REGS2_k127_3151220_2 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000001097 180.0
REGS2_k127_3160300_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 569.0
REGS2_k127_3160300_1 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 463.0
REGS2_k127_3160300_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 379.0
REGS2_k127_316348_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 6.211e-286 892.0
REGS2_k127_316348_1 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 403.0
REGS2_k127_316348_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 381.0
REGS2_k127_316348_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004145 276.0
REGS2_k127_316348_4 Transcriptional regulatory protein, C terminal - - - 0.000000000004275 70.0
REGS2_k127_316348_5 Armadillo/beta-catenin-like repeats - - - 0.00000003683 66.0
REGS2_k127_3166154_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 3.434e-227 712.0
REGS2_k127_3166154_1 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
REGS2_k127_3210110_0 Amidohydrolase family K06015 - 3.5.1.81 7.235e-258 817.0
REGS2_k127_3210110_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 572.0
REGS2_k127_3210110_10 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000173 143.0
REGS2_k127_3210110_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 477.0
REGS2_k127_3210110_3 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 466.0
REGS2_k127_3210110_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
REGS2_k127_3210110_5 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000154 292.0
REGS2_k127_3210110_6 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002895 228.0
REGS2_k127_3210110_7 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000001461 232.0
REGS2_k127_3210110_8 Chemotaxis phosphatase CheX K03409 - - 0.000000000000000000000000000000000000000000000000000000000009792 222.0
REGS2_k127_3210110_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000004507 179.0
REGS2_k127_3215804_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.261e-221 691.0
REGS2_k127_3215804_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000005172 135.0
REGS2_k127_3215804_2 Transglycosylase associated protein - - - 0.00000000000000000003746 94.0
REGS2_k127_3224015_0 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000007533 239.0
REGS2_k127_3224015_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000001083 209.0
REGS2_k127_3244540_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 430.0
REGS2_k127_3244540_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 340.0
REGS2_k127_3244540_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
REGS2_k127_3244540_3 Carboxypeptidase regulatory-like domain - - - 0.0003485 46.0
REGS2_k127_3253576_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 5.698e-270 835.0
REGS2_k127_3253576_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 397.0
REGS2_k127_3253576_2 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 316.0
REGS2_k127_3253576_3 PFAM Cytochrome c assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001281 290.0
REGS2_k127_3253576_4 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
REGS2_k127_3253576_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000007408 241.0
REGS2_k127_3253576_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000004446 174.0
REGS2_k127_3253576_7 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000007035 57.0
REGS2_k127_3257002_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 441.0
REGS2_k127_3257002_1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
REGS2_k127_3257002_2 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000007562 257.0
REGS2_k127_3257002_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000079 89.0
REGS2_k127_3263386_0 PFAM Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 446.0
REGS2_k127_3263386_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000005505 249.0
REGS2_k127_3263386_2 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000001542 183.0
REGS2_k127_3263386_3 NACHT domain - - - 0.000000000000000000000000000000006016 143.0
REGS2_k127_3263386_4 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000002854 110.0
REGS2_k127_3278306_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 499.0
REGS2_k127_3278306_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 360.0
REGS2_k127_3287585_0 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 1.787e-197 626.0
REGS2_k127_3287585_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 377.0
REGS2_k127_3287585_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
REGS2_k127_3287585_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000009675 233.0
REGS2_k127_3287585_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000001653 200.0
REGS2_k127_3287585_5 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000005007 185.0
REGS2_k127_3287585_6 Bacterial regulatory proteins, tetR family K09017 - - 0.000007971 50.0
REGS2_k127_3292121_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 542.0
REGS2_k127_3292121_1 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000006083 125.0
REGS2_k127_3292121_2 Belongs to the ATPase B chain family K02109 - - 0.00000000000000000000001158 102.0
REGS2_k127_3293488_0 Permease, YjgP YjgQ - - - 2.274e-300 939.0
REGS2_k127_3307055_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 402.0
REGS2_k127_3307055_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000008075 94.0
REGS2_k127_3308147_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000007644 119.0
REGS2_k127_3310683_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1116.0
REGS2_k127_3310683_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000001096 137.0
REGS2_k127_3327428_0 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 325.0
REGS2_k127_3327428_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000002395 164.0
REGS2_k127_333460_0 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009267 270.0
REGS2_k127_333460_1 Cytochrome c K02305 - - 0.0000000000000000000000000000000000007985 148.0
REGS2_k127_333460_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000005555 136.0
REGS2_k127_333460_3 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000007002 130.0
REGS2_k127_333460_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000003272 91.0
REGS2_k127_3344822_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.039e-260 811.0
REGS2_k127_3344822_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 327.0
REGS2_k127_3344822_2 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000004904 202.0
REGS2_k127_3359941_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.671e-282 879.0
REGS2_k127_3359941_1 Sigma factor PP2C-like phosphatases - - - 5.833e-231 729.0
REGS2_k127_3359941_10 - - - - 0.00000000000000000000000000000125 124.0
REGS2_k127_3359941_11 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000002949 111.0
REGS2_k127_3359941_12 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000202 96.0
REGS2_k127_3359941_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 343.0
REGS2_k127_3359941_3 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 339.0
REGS2_k127_3359941_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 320.0
REGS2_k127_3359941_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 304.0
REGS2_k127_3359941_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002156 279.0
REGS2_k127_3359941_7 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003826 249.0
REGS2_k127_3359941_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000000000000000000001726 169.0
REGS2_k127_3359941_9 - - - - 0.000000000000000000000000000000000000000005366 158.0
REGS2_k127_3401417_0 heat shock protein 70 K04043,K04044 - - 3.439e-316 978.0
REGS2_k127_3401417_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000001001 66.0
REGS2_k127_342452_0 Transposase domain (DUF772) K07487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 473.0
REGS2_k127_342452_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000006651 139.0
REGS2_k127_3434773_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 7.517e-256 795.0
REGS2_k127_3434773_1 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 445.0
REGS2_k127_3434773_2 membrane - - - 0.000000000000000000000000000000000008166 145.0
REGS2_k127_3434773_3 membrane - - - 0.0000000000000000000000000000009303 125.0
REGS2_k127_3434773_4 PFAM Outer membrane efflux protein - - - 0.0000000000000000001202 97.0
REGS2_k127_3442349_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 540.0
REGS2_k127_3442349_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 442.0
REGS2_k127_3442349_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 310.0
REGS2_k127_3442349_3 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000000000002158 195.0
REGS2_k127_3442349_4 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000000000001411 119.0
REGS2_k127_344271_0 Sortilin, neurotensin receptor 3, - - - 0.0 1036.0
REGS2_k127_344271_1 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000001239 179.0
REGS2_k127_344271_2 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000001514 153.0
REGS2_k127_344904_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 440.0
REGS2_k127_344904_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 429.0
REGS2_k127_344904_2 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000008358 217.0
REGS2_k127_344904_3 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000129 136.0
REGS2_k127_3454419_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 425.0
REGS2_k127_3454419_1 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 346.0
REGS2_k127_3454419_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
REGS2_k127_3455916_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 471.0
REGS2_k127_3455916_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000001534 176.0
REGS2_k127_3455916_2 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000001958 152.0
REGS2_k127_3467184_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 498.0
REGS2_k127_3467184_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000006005 207.0
REGS2_k127_3495145_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 524.0
REGS2_k127_3495145_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000006005 143.0
REGS2_k127_3520337_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 477.0
REGS2_k127_3520337_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000005151 158.0
REGS2_k127_3520337_2 chaperone-mediated protein folding - - - 0.000000000002169 78.0
REGS2_k127_3568087_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1069.0
REGS2_k127_3568087_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 8.509e-288 889.0
REGS2_k127_3568087_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 335.0
REGS2_k127_3568087_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 334.0
REGS2_k127_3568087_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001496 276.0
REGS2_k127_3568087_5 Protein of unknown function (DUF1264) - - - 0.000000000000000000000000000000000000000000000000000000000001328 216.0
REGS2_k127_3568087_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000001809 187.0
REGS2_k127_3568087_7 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000005188 165.0
REGS2_k127_3570707_0 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 379.0
REGS2_k127_3591960_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 377.0
REGS2_k127_3591960_1 - - - - 0.0005852 48.0
REGS2_k127_3593287_0 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 409.0
REGS2_k127_3593287_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 371.0
REGS2_k127_3593287_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
REGS2_k127_3593287_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
REGS2_k127_3593287_4 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 269.0
REGS2_k127_3593287_5 integral membrane protein - - - 0.000000000000000000000000009675 115.0
REGS2_k127_3593287_6 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000001856 113.0
REGS2_k127_3593287_7 heat shock protein binding - - - 0.0000000003534 64.0
REGS2_k127_3597899_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 295.0
REGS2_k127_3597899_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000002998 226.0
REGS2_k127_3597899_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000001039 108.0
REGS2_k127_3607685_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1141.0
REGS2_k127_3607685_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 9.402e-255 804.0
REGS2_k127_3607685_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.217e-240 754.0
REGS2_k127_3607685_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 488.0
REGS2_k127_3607685_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 389.0
REGS2_k127_3607685_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 377.0
REGS2_k127_3607685_6 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000003568 200.0
REGS2_k127_3607685_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000837 154.0
REGS2_k127_3614_0 Domain of unknown function (DUF3488) - - - 1.318e-196 635.0
REGS2_k127_3614_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 348.0
REGS2_k127_3614_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000004201 220.0
REGS2_k127_3645695_0 Sodium:solute symporter family - - - 9.019e-294 913.0
REGS2_k127_3645695_1 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 383.0
REGS2_k127_3645695_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
REGS2_k127_3645695_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000003748 76.0
REGS2_k127_3703758_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 427.0
REGS2_k127_3703758_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000001017 148.0
REGS2_k127_3703758_2 - - - - 0.0000000000000000000000004383 110.0
REGS2_k127_3703758_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000008672 105.0
REGS2_k127_3753044_0 Ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 473.0
REGS2_k127_3753044_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000006419 102.0
REGS2_k127_3755787_0 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 467.0
REGS2_k127_3755787_1 protocatechuate 3,4-dioxygenase activity - - - 0.000000000001069 73.0
REGS2_k127_376862_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 346.0
REGS2_k127_3783505_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1125.0
REGS2_k127_3783505_1 Elongation factor SelB, winged helix K03833 - - 5.318e-240 758.0
REGS2_k127_3783505_10 Carboxymuconolactone decarboxylase family - - - 0.00002668 51.0
REGS2_k127_3783505_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.412e-236 750.0
REGS2_k127_3783505_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 555.0
REGS2_k127_3783505_4 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 453.0
REGS2_k127_3783505_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 329.0
REGS2_k127_3783505_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000007985 54.0
REGS2_k127_3783505_7 DNA ligase N terminus K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000007525 49.0
REGS2_k127_3783505_8 YtkA-like - - - 0.00001663 51.0
REGS2_k127_3783505_9 - - - - 0.00001984 53.0
REGS2_k127_3794328_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.408e-257 808.0
REGS2_k127_3794328_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.055e-234 747.0
REGS2_k127_3794328_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 520.0
REGS2_k127_3794328_3 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 403.0
REGS2_k127_3805514_0 PFAM Cytochrome c assembly protein K02198 - - 4.502e-302 938.0
REGS2_k127_3805514_1 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000003945 169.0
REGS2_k127_3805514_2 - - - - 0.00000000000000000006359 96.0
REGS2_k127_3806399_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 505.0
REGS2_k127_3806399_1 Putative peptidoglycan binding domain - - - 0.0000000000000000000000003846 111.0
REGS2_k127_3808429_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.891e-217 681.0
REGS2_k127_3808429_1 Aminotransferase class-V K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 457.0
REGS2_k127_3808429_2 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 436.0
REGS2_k127_3808429_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 353.0
REGS2_k127_3808429_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 329.0
REGS2_k127_3808429_5 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 331.0
REGS2_k127_3808429_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003313 252.0
REGS2_k127_3808429_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000007451 85.0
REGS2_k127_3829582_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 422.0
REGS2_k127_3829582_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 312.0
REGS2_k127_3829582_2 Evidence 2b Function of strongly homologous gene K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 289.0
REGS2_k127_3829582_3 TOBE domain - - - 0.000000000000000007265 86.0
REGS2_k127_3834821_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 535.0
REGS2_k127_3834821_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005384 282.0
REGS2_k127_3834821_2 peptidase inhibitor activity - - - 0.0000000000000000000000000000000005589 142.0
REGS2_k127_3840897_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 364.0
REGS2_k127_3840897_1 Belongs to the CDS family K00981 - 2.7.7.41 0.00002978 52.0
REGS2_k127_3891417_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1049.0
REGS2_k127_3931570_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 598.0
REGS2_k127_3931570_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 466.0
REGS2_k127_3963278_0 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 403.0
REGS2_k127_3963278_1 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 320.0
REGS2_k127_3963278_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000001041 200.0
REGS2_k127_3972419_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 412.0
REGS2_k127_3972419_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 383.0
REGS2_k127_3972419_2 ATP-grasp domain - - - 0.0000000000000261 74.0
REGS2_k127_3972419_3 C4-type zinc ribbon domain K07164 - - 0.0009687 42.0
REGS2_k127_403596_0 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 301.0
REGS2_k127_403596_1 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007283 273.0
REGS2_k127_403596_2 DinB family - - - 0.00000000000000000000000000000000000000000000000003598 183.0
REGS2_k127_4038276_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 408.0
REGS2_k127_4038276_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 304.0
REGS2_k127_4038276_2 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000007686 244.0
REGS2_k127_4038276_3 - - - - 0.00000000000000000000000000000000006985 142.0
REGS2_k127_4057047_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0 1093.0
REGS2_k127_4057047_1 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000226 183.0
REGS2_k127_4057047_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000001558 130.0
REGS2_k127_4064313_0 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 526.0
REGS2_k127_4064313_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 308.0
REGS2_k127_4064313_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000009856 215.0
REGS2_k127_4064313_3 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000001025 171.0
REGS2_k127_4075_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 394.0
REGS2_k127_4075_1 - - - - 0.00000000000000005934 85.0
REGS2_k127_4075214_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
REGS2_k127_4075214_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 316.0
REGS2_k127_4075214_2 polyphosphate kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002962 250.0
REGS2_k127_4075214_3 CHAD - - - 0.0000002095 63.0
REGS2_k127_4076943_0 PFAM Glycosyl transferase family 2 - - - 2.29e-274 853.0
REGS2_k127_4085828_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 510.0
REGS2_k127_4085828_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 356.0
REGS2_k127_4085828_2 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 306.0
REGS2_k127_4085828_3 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000008044 126.0
REGS2_k127_4085828_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000002863 96.0
REGS2_k127_4085828_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000005872 55.0
REGS2_k127_40864_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 501.0
REGS2_k127_40864_1 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008007 280.0
REGS2_k127_4093695_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 594.0
REGS2_k127_4093695_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000001687 202.0
REGS2_k127_4093695_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000124 77.0
REGS2_k127_4108865_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 319.0
REGS2_k127_4108865_1 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 293.0
REGS2_k127_4108865_2 ABC-2 type transporter - - - 0.000000001305 66.0
REGS2_k127_412083_0 Bacterial regulatory protein, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 341.0
REGS2_k127_4125019_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 464.0
REGS2_k127_4125019_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0000764 51.0
REGS2_k127_4152464_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 7.03e-213 670.0
REGS2_k127_4152464_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001718 234.0
REGS2_k127_4152464_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0003061 43.0
REGS2_k127_4165427_0 - - - - 0.000000000000000000000000000000002487 133.0
REGS2_k127_4165427_1 - - - - 0.0000000006007 72.0
REGS2_k127_4165427_2 - - - - 0.000885 46.0
REGS2_k127_4202222_0 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 308.0
REGS2_k127_4202222_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000004997 175.0
REGS2_k127_4203035_0 DNA polymerase X family K02347 - - 2.231e-243 760.0
REGS2_k127_4203035_1 - - - - 0.0000000000000000000000000000000000000217 151.0
REGS2_k127_4232740_0 Glycosyltransferase family 20 - - - 1.25e-260 818.0
REGS2_k127_4232740_1 PFAM Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000001718 95.0
REGS2_k127_4246958_0 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000279 278.0
REGS2_k127_4246958_1 PFAM Cytochrome c assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000001855 182.0
REGS2_k127_4246958_2 PFAM response regulator receiveR - - - 0.0000000000000000000000000000000000000000000000000562 185.0
REGS2_k127_4246958_3 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000006093 126.0
REGS2_k127_4266140_0 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 303.0
REGS2_k127_4266140_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002453 250.0
REGS2_k127_4283020_0 NHL repeat - - - 0.0000000000000000000000109 117.0
REGS2_k127_4283020_1 Polysulphide reductase, NrfD K00185 - - 0.000000000349 65.0
REGS2_k127_4283020_2 PFAM doubled CXXCH domain protein - - - 0.0000001532 61.0
REGS2_k127_4329980_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 451.0
REGS2_k127_4329980_1 ABC transporter transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001314 259.0
REGS2_k127_4329980_2 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000004374 182.0
REGS2_k127_4352545_0 SpoIVB peptidase S55 - - - 2.4e-237 747.0
REGS2_k127_4352545_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000009482 205.0
REGS2_k127_4373094_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 535.0
REGS2_k127_4373094_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003471 247.0
REGS2_k127_437699_0 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 332.0
REGS2_k127_437699_1 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000000000000001679 124.0
REGS2_k127_437699_2 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000004841 87.0
REGS2_k127_437699_3 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000009091 61.0
REGS2_k127_4384578_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 489.0
REGS2_k127_4384578_1 EamA-like transporter family K07790 - - 0.000000000000000000000000000001045 133.0
REGS2_k127_4396288_0 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000838 150.0
REGS2_k127_4396288_1 - - - - 0.000000000000000000000000004076 116.0
REGS2_k127_4396288_2 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000008536 115.0
REGS2_k127_440037_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 591.0
REGS2_k127_440037_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 574.0
REGS2_k127_440037_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 531.0
REGS2_k127_440037_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 344.0
REGS2_k127_440037_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 306.0
REGS2_k127_440037_5 Alpha/beta hydrolase family K22318 - - 0.00000000000000000000000000000000000000000000000000000000000006478 226.0
REGS2_k127_440037_6 YbbR-like protein - - - 0.000000000000000000000000000000000000000000000000000202 205.0
REGS2_k127_440037_7 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000003035 134.0
REGS2_k127_4409089_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 381.0
REGS2_k127_4412367_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 468.0
REGS2_k127_4412367_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001436 262.0
REGS2_k127_4412367_2 Zn peptidase - - - 0.00000000549 62.0
REGS2_k127_4414248_0 signal transduction histidine kinase - - - 2.78e-288 904.0
REGS2_k127_4414248_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 1.259e-240 754.0
REGS2_k127_4414248_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 466.0
REGS2_k127_4414248_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 414.0
REGS2_k127_4414248_4 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 383.0
REGS2_k127_4414248_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000005842 158.0
REGS2_k127_4414248_6 Class III cytochrome C family - - - 0.000000000003965 72.0
REGS2_k127_4449358_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 548.0
REGS2_k127_4449358_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.000000000000000003822 86.0
REGS2_k127_4449706_0 PA domain - - - 2.126e-216 681.0
REGS2_k127_4449706_1 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.000000000000000000000000000000000000000002332 166.0
REGS2_k127_4451301_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 426.0
REGS2_k127_4451301_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 375.0
REGS2_k127_4451301_2 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 357.0
REGS2_k127_4451301_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 329.0
REGS2_k127_4453727_0 Bacterial protein of unknown function (DUF885) - - - 1.132e-210 670.0
REGS2_k127_4453727_1 Histidine kinase K02482,K03557 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 556.0
REGS2_k127_4453727_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000007926 158.0
REGS2_k127_4458200_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 450.0
REGS2_k127_4458200_1 - - - - 0.000000000000000000000000000000000000000000003021 176.0
REGS2_k127_4505664_0 Tetratricopeptide repeat - - - 1.229e-262 829.0
REGS2_k127_4505664_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 549.0
REGS2_k127_4505664_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 521.0
REGS2_k127_4505664_3 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 306.0
REGS2_k127_4505664_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000001262 190.0
REGS2_k127_4505664_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000002984 173.0
REGS2_k127_4507987_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 581.0
REGS2_k127_4507987_1 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 452.0
REGS2_k127_4507987_2 Mov34 MPN PAD-1 - - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
REGS2_k127_4507987_3 ThiS family K03636 - - 0.0000000000000000000000000000000002724 133.0
REGS2_k127_4522633_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 4.881e-229 719.0
REGS2_k127_4522633_1 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 373.0
REGS2_k127_4522633_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000007116 247.0
REGS2_k127_4532632_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000393 243.0
REGS2_k127_4532632_1 Protein of unknown function (DUF4230) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
REGS2_k127_4532632_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001041 220.0
REGS2_k127_4563910_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000001373 157.0
REGS2_k127_4563910_1 Transposase - - - 0.00000000000000000000000000005041 130.0
REGS2_k127_4570254_0 amino acid K03294 - - 8.911e-242 771.0
REGS2_k127_4570254_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000009459 235.0
REGS2_k127_4570254_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000002126 222.0
REGS2_k127_4571922_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 354.0
REGS2_k127_4571922_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 338.0
REGS2_k127_4571922_2 - - - - 0.00000000000000000000000001886 114.0
REGS2_k127_4574355_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 561.0
REGS2_k127_4599567_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 435.0
REGS2_k127_4599567_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 350.0
REGS2_k127_4599567_2 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000004474 158.0
REGS2_k127_4604597_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 6.863e-211 670.0
REGS2_k127_4604597_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 411.0
REGS2_k127_4604597_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000002769 128.0
REGS2_k127_4604597_3 - - - - 0.000000000000000004644 95.0
REGS2_k127_4619087_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 558.0
REGS2_k127_4619087_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 550.0
REGS2_k127_4619087_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000003166 135.0
REGS2_k127_4619588_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 569.0
REGS2_k127_4619588_1 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000004908 193.0
REGS2_k127_4619588_2 - - - - 0.00000001657 64.0
REGS2_k127_462574_0 PFAM Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001028 275.0
REGS2_k127_462574_1 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000001162 103.0
REGS2_k127_462574_2 ABC transporter permease K02026 - - 0.0000000000000005129 80.0
REGS2_k127_4631239_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 325.0
REGS2_k127_4631239_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000001153 240.0
REGS2_k127_4631239_2 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008043 239.0
REGS2_k127_4635283_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 1.289e-249 786.0
REGS2_k127_4635283_1 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001076 262.0
REGS2_k127_4637493_0 Histidine kinase K02482 - 2.7.13.3 1.177e-273 866.0
REGS2_k127_4637493_1 Bacterial regulatory protein, Fis family - - - 3.14e-211 674.0
REGS2_k127_4637493_2 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000008846 167.0
REGS2_k127_4640079_0 Amino acid permease - - - 4.85e-300 939.0
REGS2_k127_4640079_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 543.0
REGS2_k127_4640079_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 509.0
REGS2_k127_4640079_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000824 254.0
REGS2_k127_4640079_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000002649 184.0
REGS2_k127_4641112_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 5.387e-211 661.0
REGS2_k127_4641112_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 323.0
REGS2_k127_4641112_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000001234 196.0
REGS2_k127_4641112_3 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000002749 184.0
REGS2_k127_4641112_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000002126 175.0
REGS2_k127_4641112_5 PFAM Chorismate mutase, type II - - - 0.000000000000000000000000000000001427 132.0
REGS2_k127_4653643_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 430.0
REGS2_k127_4653643_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000004188 205.0
REGS2_k127_465997_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 346.0
REGS2_k127_465997_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 350.0
REGS2_k127_465997_2 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000001981 208.0
REGS2_k127_465997_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000002875 86.0
REGS2_k127_4665578_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 485.0
REGS2_k127_4665578_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000005171 209.0
REGS2_k127_4665578_3 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000009664 150.0
REGS2_k127_4665578_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000001013 100.0
REGS2_k127_4665578_5 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.00000001029 61.0
REGS2_k127_4668800_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 341.0
REGS2_k127_4668800_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 342.0
REGS2_k127_4668800_2 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000009105 191.0
REGS2_k127_4688694_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 521.0
REGS2_k127_4688694_1 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000002618 158.0
REGS2_k127_4736078_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007031 235.0
REGS2_k127_4736078_1 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000002083 198.0
REGS2_k127_4741249_0 Oligoendopeptidase f - - - 1.884e-249 789.0
REGS2_k127_4741249_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 3.14e-212 669.0
REGS2_k127_4741249_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002215 270.0
REGS2_k127_4741249_3 O-methyltransferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001575 273.0
REGS2_k127_4741249_4 Adenylate cyclase - - - 0.00000000000000000000000001311 112.0
REGS2_k127_4741249_5 Ferredoxin - - - 0.0000000000000000005336 100.0
REGS2_k127_4744423_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.812e-246 773.0
REGS2_k127_4744423_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 4.212e-229 713.0
REGS2_k127_4744423_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 563.0
REGS2_k127_4744423_3 Regulatory protein - - - 0.00000000000000000000000000000000000000006018 156.0
REGS2_k127_4744423_4 Predicted membrane protein (DUF2085) - - - 0.0002835 49.0
REGS2_k127_4744790_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 501.0
REGS2_k127_4744790_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 310.0
REGS2_k127_4744790_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002714 253.0
REGS2_k127_4744790_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000007442 171.0
REGS2_k127_4745414_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.254e-234 730.0
REGS2_k127_4745414_1 - - - - 0.000000000000000000000000000000000000000000000006125 190.0
REGS2_k127_4745414_2 - - - - 0.0000000000000000000000000000000002158 148.0
REGS2_k127_4746301_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 452.0
REGS2_k127_4746301_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019538,GO:0020037,GO:0030091,GO:0031224,GO:0031226,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000001851 249.0
REGS2_k127_4746301_2 - - - - 0.00000007376 56.0
REGS2_k127_4756166_0 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 483.0
REGS2_k127_4756166_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006379 269.0
REGS2_k127_4756166_2 cellular response to heat K09807 - - 0.000000000000000000000000000000000000000000000000000000000000000000001768 248.0
REGS2_k127_4756166_3 multi-organism process K03195 - - 0.00000000000000000000000000000000000000000000000000000000000000000004166 241.0
REGS2_k127_4760426_0 ABC transporter K11085 - - 3.842e-263 824.0
REGS2_k127_4760426_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 542.0
REGS2_k127_4760426_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 446.0
REGS2_k127_4760426_3 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 377.0
REGS2_k127_4760426_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002476 272.0
REGS2_k127_4760426_5 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000005032 262.0
REGS2_k127_4760426_6 Ribosomal subunit interface protein K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
REGS2_k127_4760426_7 Evidence 4 Homologs of previously reported genes of K21440 - - 0.000000000000000000000000000000000001428 153.0
REGS2_k127_4760426_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000003692 97.0
REGS2_k127_4760976_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 380.0
REGS2_k127_4760976_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 324.0
REGS2_k127_4760976_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000003236 227.0
REGS2_k127_4760976_3 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000003594 181.0
REGS2_k127_4760976_4 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000003892 170.0
REGS2_k127_4782907_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 1.413e-306 958.0
REGS2_k127_4782907_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 480.0
REGS2_k127_4782907_2 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 479.0
REGS2_k127_4782907_3 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 317.0
REGS2_k127_4782907_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000003149 189.0
REGS2_k127_4782907_5 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000004195 172.0
REGS2_k127_4794156_0 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 391.0
REGS2_k127_4794156_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
REGS2_k127_4794156_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000001581 264.0
REGS2_k127_4794156_3 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000001118 169.0
REGS2_k127_4794156_4 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000001543 157.0
REGS2_k127_4794156_5 Protein of unknown function (DUF465) - - - 0.000000000000000000003135 95.0
REGS2_k127_4794156_6 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000004278 98.0
REGS2_k127_4794156_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000002933 72.0
REGS2_k127_4831141_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1116.0
REGS2_k127_4831141_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000003041 195.0
REGS2_k127_4831141_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000005365 161.0
REGS2_k127_484278_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0 1058.0
REGS2_k127_484278_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 3.403e-257 803.0
REGS2_k127_484278_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000007379 232.0
REGS2_k127_484278_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000006818 210.0
REGS2_k127_484278_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000002397 171.0
REGS2_k127_484278_5 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000002948 102.0
REGS2_k127_4846861_0 Response regulator receiver K07714 - - 4.582e-201 634.0
REGS2_k127_4846861_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 323.0
REGS2_k127_4846861_2 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 293.0
REGS2_k127_4846861_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000005198 111.0
REGS2_k127_4865088_0 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 508.0
REGS2_k127_4865088_1 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001026 218.0
REGS2_k127_4865088_2 AAA domain - - - 0.0000000000000000000000000000000000000000156 159.0
REGS2_k127_4865088_3 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.00000000000000000000000006226 124.0
REGS2_k127_48774_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 529.0
REGS2_k127_48774_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 457.0
REGS2_k127_48774_2 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 450.0
REGS2_k127_48774_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000009376 214.0
REGS2_k127_48774_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000003744 163.0
REGS2_k127_4877922_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 490.0
REGS2_k127_4877922_1 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000001105 121.0
REGS2_k127_4877922_3 COGs COG0659 Sulfate permease and related transporter (MFS superfamily) - - - 0.0009181 45.0
REGS2_k127_4877950_0 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000003334 190.0
REGS2_k127_4877950_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000002135 189.0
REGS2_k127_4877950_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000003722 171.0
REGS2_k127_4892973_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 461.0
REGS2_k127_4893694_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 458.0
REGS2_k127_4893694_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 421.0
REGS2_k127_4893694_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 410.0
REGS2_k127_4893694_3 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000121 235.0
REGS2_k127_4893694_4 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002683 237.0
REGS2_k127_4893694_5 chaperone-mediated protein folding - - - 0.0000000000000000000000000001806 117.0
REGS2_k127_4893775_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 5.052e-230 729.0
REGS2_k127_4893775_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 325.0
REGS2_k127_4893775_2 DinB superfamily - - - 0.0000000000000000000001184 104.0
REGS2_k127_489413_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.646e-257 813.0
REGS2_k127_489413_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.175e-209 668.0
REGS2_k127_489413_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 340.0
REGS2_k127_489413_3 - - - - 0.000000000000000000000000000000000000000000000000000302 192.0
REGS2_k127_489413_4 PFAM ThiJ PfpI domain protein - - - 0.00000000000000000000000000000000000000000000000005634 186.0
REGS2_k127_489413_5 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000008305 169.0
REGS2_k127_489413_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000001247 129.0
REGS2_k127_489413_7 antisigma factor binding K04749 - - 0.00000000000000000000000000001422 123.0
REGS2_k127_4905753_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 6.259e-265 822.0
REGS2_k127_4905753_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 504.0
REGS2_k127_4905753_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 381.0
REGS2_k127_4905753_3 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 359.0
REGS2_k127_4905753_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000241 277.0
REGS2_k127_4905753_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
REGS2_k127_4905753_6 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000002901 242.0
REGS2_k127_4905753_7 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000009019 216.0
REGS2_k127_4905753_8 membrane - - - 0.000000000000000000000000000000000009102 139.0
REGS2_k127_4905753_9 membrane - - - 0.00000000000000000000000000000000007114 138.0
REGS2_k127_4969828_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 474.0
REGS2_k127_4969828_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
REGS2_k127_498588_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 4.769e-267 844.0
REGS2_k127_498588_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 378.0
REGS2_k127_498588_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 312.0
REGS2_k127_498588_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 291.0
REGS2_k127_498588_4 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 296.0
REGS2_k127_498588_5 Aminotransferase class-V K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000001948 205.0
REGS2_k127_498588_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000005514 156.0
REGS2_k127_498588_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000354 131.0
REGS2_k127_498588_8 - - - - 0.000000000000001192 91.0
REGS2_k127_4998409_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 571.0
REGS2_k127_4998409_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 574.0
REGS2_k127_4998409_2 Serine aminopeptidase, S33 K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 377.0
REGS2_k127_4998409_3 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000327 232.0
REGS2_k127_4998409_4 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000000000001621 182.0
REGS2_k127_4998409_5 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000002183 178.0
REGS2_k127_4998409_6 - - - - 0.0000000000000000000000000000003918 130.0
REGS2_k127_4998409_7 Regulatory protein, FmdB family - - - 0.000000000000291 78.0
REGS2_k127_4998409_8 FtsK/SpoIIIE family K03466 - - 0.0003889 48.0
REGS2_k127_5002923_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 468.0
REGS2_k127_5002923_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000431 272.0
REGS2_k127_5014479_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 7.724e-237 748.0
REGS2_k127_5014479_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 366.0
REGS2_k127_5014479_2 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 366.0
REGS2_k127_5014479_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 291.0
REGS2_k127_5014479_4 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002257 244.0
REGS2_k127_5014479_5 - - - - 0.0000008843 53.0
REGS2_k127_5029897_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 391.0
REGS2_k127_5029897_1 Protein tyrosine kinase - - - 0.000001656 61.0
REGS2_k127_5041583_0 Radical SAM superfamily K06937 - - 1.728e-309 953.0
REGS2_k127_5041664_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001615 255.0
REGS2_k127_5041664_1 repeat-containing protein - - - 0.000000000001875 77.0
REGS2_k127_5068284_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 444.0
REGS2_k127_5068284_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
REGS2_k127_5068284_2 GAF domain - - - 0.000000000000000000000000000000000000000000001237 172.0
REGS2_k127_5068284_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000002004 93.0
REGS2_k127_5089086_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.879e-228 712.0
REGS2_k127_5089086_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000001515 194.0
REGS2_k127_5089086_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000003137 159.0
REGS2_k127_5094812_0 maltose O-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 336.0
REGS2_k127_5094812_1 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 305.0
REGS2_k127_5094812_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
REGS2_k127_5095286_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1360.0
REGS2_k127_5095286_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 399.0
REGS2_k127_5095286_2 - - - - 0.00000000000000000000000000000000000000000000000002891 183.0
REGS2_k127_5095286_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000007886 105.0
REGS2_k127_5102409_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 384.0
REGS2_k127_5102409_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 305.0
REGS2_k127_5102409_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000001682 224.0
REGS2_k127_5110109_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 542.0
REGS2_k127_5110109_1 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 497.0
REGS2_k127_5110109_2 cAMP biosynthetic process K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 358.0
REGS2_k127_5110109_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000002105 190.0
REGS2_k127_5110109_4 DoxX K15977 - - 0.000000000000000000000000000000000000037 147.0
REGS2_k127_5110109_5 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000004498 98.0
REGS2_k127_5126034_0 Transposase - - - 0.0000000000000000000000000000000000000001811 165.0
REGS2_k127_5133751_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 571.0
REGS2_k127_5133751_1 PFAM aminotransferase class V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 543.0
REGS2_k127_5133751_2 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
REGS2_k127_5133751_3 - - - - 0.00000000000000000000000000000007137 132.0
REGS2_k127_5133751_4 YtxH-like protein - - - 0.00000000000000000000000001006 112.0
REGS2_k127_5133751_5 Alternative locus ID - - - 0.00008087 49.0
REGS2_k127_5174832_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002918 261.0
REGS2_k127_5174832_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000003636 228.0
REGS2_k127_5174832_2 Mycolic acid cyclopropane synthetase K05929 - 2.1.1.103 0.00000000000000000000000000000000000000000000001069 182.0
REGS2_k127_5174832_3 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000001381 150.0
REGS2_k127_5193953_0 Permease, YjgP YjgQ - - - 1.201e-278 877.0
REGS2_k127_5193953_1 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 559.0
REGS2_k127_5193953_2 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000641 212.0
REGS2_k127_519640_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1194.0
REGS2_k127_519640_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 446.0
REGS2_k127_519640_2 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 307.0
REGS2_k127_519640_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001049 280.0
REGS2_k127_5211431_0 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 476.0
REGS2_k127_5211431_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 432.0
REGS2_k127_5223195_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 1.102e-194 636.0
REGS2_k127_5223195_1 peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 521.0
REGS2_k127_5223195_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 471.0
REGS2_k127_5223195_3 Gas vesicle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 329.0
REGS2_k127_5223195_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000479 179.0
REGS2_k127_5223195_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000004871 180.0
REGS2_k127_5223195_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000006706 154.0
REGS2_k127_5223195_8 YjbR - - - 0.0000000000000000000000000000574 127.0
REGS2_k127_5223195_9 Trm112p-like protein K09791 - - 0.000000000000003447 76.0
REGS2_k127_5271654_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 482.0
REGS2_k127_5271654_1 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 456.0
REGS2_k127_5271654_2 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000001755 224.0
REGS2_k127_5271654_3 ACT domain protein - - - 0.0000000000000006512 84.0
REGS2_k127_5343484_0 Two component regulator propeller - - - 2.45e-214 685.0
REGS2_k127_5343484_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 381.0
REGS2_k127_5343484_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000003615 72.0
REGS2_k127_5359733_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1667.0
REGS2_k127_5359733_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001087 274.0
REGS2_k127_536505_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 468.0
REGS2_k127_536505_1 oxidoreductase activity, acting on diphenols and related substances as donors K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 256.0
REGS2_k127_5370154_0 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 301.0
REGS2_k127_5370154_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000001108 191.0
REGS2_k127_5370154_2 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000007461 173.0
REGS2_k127_537198_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 9.245e-202 632.0
REGS2_k127_537198_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 607.0
REGS2_k127_537198_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 570.0
REGS2_k127_537198_3 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 333.0
REGS2_k127_537198_4 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001598 271.0
REGS2_k127_537198_6 - K05826 - - 0.0000000009625 63.0
REGS2_k127_5389687_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 370.0
REGS2_k127_5389687_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 292.0
REGS2_k127_539374_0 Malate synthase K01638 - 2.3.3.9 2.33e-230 724.0
REGS2_k127_539374_1 Isocitrate lyase family K01637 - 4.1.3.1 6.949e-195 621.0
REGS2_k127_539374_2 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000001479 177.0
REGS2_k127_5397054_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 524.0
REGS2_k127_5397054_1 transmembrane transporter activity K03296,K07788,K07789 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 484.0
REGS2_k127_5402220_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000007642 161.0
REGS2_k127_5402220_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000001451 147.0
REGS2_k127_5402220_2 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001394 136.0
REGS2_k127_5406146_0 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 502.0
REGS2_k127_5413502_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000147 186.0
REGS2_k127_5424337_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 372.0
REGS2_k127_5424337_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 328.0
REGS2_k127_5424337_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000001779 208.0
REGS2_k127_5424337_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000004435 191.0
REGS2_k127_5424337_4 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000002485 184.0
REGS2_k127_5424337_5 - - - - 0.000000000000000000000000000000000000000004523 174.0
REGS2_k127_5424337_6 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000004236 115.0
REGS2_k127_5425618_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 549.0
REGS2_k127_5425618_1 excinuclease ABC activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 461.0
REGS2_k127_5425618_2 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 340.0
REGS2_k127_5425618_3 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000005125 129.0
REGS2_k127_5425618_4 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000009527 123.0
REGS2_k127_5425618_5 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000003987 100.0
REGS2_k127_5425618_6 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000001062 55.0
REGS2_k127_5427240_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 486.0
REGS2_k127_5427240_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 358.0
REGS2_k127_5427240_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 324.0
REGS2_k127_5457277_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 612.0
REGS2_k127_5472571_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.064e-227 716.0
REGS2_k127_5472571_1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000002729 183.0
REGS2_k127_5472571_2 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000005751 153.0
REGS2_k127_5488198_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1143.0
REGS2_k127_5488198_1 - - - - 0.0003293 49.0
REGS2_k127_5488489_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.744e-201 634.0
REGS2_k127_5488489_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000002228 172.0
REGS2_k127_5488489_2 - - - - 0.0000000000000000000000000000000000000000005333 170.0
REGS2_k127_552697_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 498.0
REGS2_k127_552697_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 439.0
REGS2_k127_552697_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 414.0
REGS2_k127_552697_3 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 373.0
REGS2_k127_552697_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000003181 254.0
REGS2_k127_552697_5 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000523 253.0
REGS2_k127_552697_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000001396 173.0
REGS2_k127_5566287_0 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 339.0
REGS2_k127_5566287_1 Glutathione peroxidase K02199 - - 0.0000000000000000000000000000000000000000000000000004861 190.0
REGS2_k127_5566287_2 Disulphide bond corrector protein DsbC - - - 0.000000000000000000000000000000000000000006418 162.0
REGS2_k127_560175_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002106 248.0
REGS2_k127_560175_1 ATP-grasp - - - 0.0000000000000000000000000000000000000000000004625 172.0
REGS2_k127_560175_2 metal-dependent phosphoesterases (PHP family) - - - 0.0000000000695 72.0
REGS2_k127_5617182_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 2.073e-203 642.0
REGS2_k127_5617182_1 polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000006655 158.0
REGS2_k127_5617182_2 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000004538 91.0
REGS2_k127_5621072_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 535.0
REGS2_k127_5621072_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 467.0
REGS2_k127_5648851_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 462.0
REGS2_k127_5648851_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 422.0
REGS2_k127_5648851_2 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 316.0
REGS2_k127_5648851_3 6-phosphogluconolactonase activity - - - 0.000000000003233 75.0
REGS2_k127_5672291_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 432.0
REGS2_k127_5672291_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000003686 133.0
REGS2_k127_5688275_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 332.0
REGS2_k127_5688275_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001137 251.0
REGS2_k127_5688275_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000004941 193.0
REGS2_k127_5688275_3 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000007289 112.0
REGS2_k127_5696385_0 ABC transporter, transmembrane K18889 - - 1.124e-267 834.0
REGS2_k127_5696385_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001154 203.0
REGS2_k127_5696385_2 Glucose inhibited division protein A - - - 0.0000000000000103 79.0
REGS2_k127_5706878_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 7.674e-304 949.0
REGS2_k127_5706878_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 448.0
REGS2_k127_5706878_2 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 431.0
REGS2_k127_5706878_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000831 90.0
REGS2_k127_5722866_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001871 187.0
REGS2_k127_5722866_2 iron-sulfur cluster-binding protein K18979 - 1.17.99.6 0.000005071 50.0
REGS2_k127_5758303_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 583.0
REGS2_k127_5758303_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 478.0
REGS2_k127_5758303_10 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000002345 108.0
REGS2_k127_5758303_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000009015 100.0
REGS2_k127_5758303_12 Zincin-like metallopeptidase - - - 0.00000000000000000008997 94.0
REGS2_k127_5758303_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 498.0
REGS2_k127_5758303_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 422.0
REGS2_k127_5758303_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 312.0
REGS2_k127_5758303_5 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
REGS2_k127_5758303_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000001617 182.0
REGS2_k127_5758303_7 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000006831 177.0
REGS2_k127_5758303_8 response regulator, receiver - - - 0.0000000000000000000000000000000000000007471 153.0
REGS2_k127_5758303_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000004972 131.0
REGS2_k127_580546_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 2.747e-297 927.0
REGS2_k127_5809138_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.853e-268 839.0
REGS2_k127_5809138_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 4.003e-237 745.0
REGS2_k127_5809138_3 secondary active sulfate transmembrane transporter activity - - - 0.0000000000000000001949 93.0
REGS2_k127_581313_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 1.35e-260 819.0
REGS2_k127_581313_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 489.0
REGS2_k127_581313_2 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000001978 198.0
REGS2_k127_581313_3 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000001199 141.0
REGS2_k127_5837021_0 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
REGS2_k127_5837021_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000001273 234.0
REGS2_k127_5837021_2 Ppx/GppA phosphatase family - - - 0.000000000000000001376 98.0
REGS2_k127_585127_0 Prokaryotic cytochrome b561 - - - 1.068e-249 788.0
REGS2_k127_585127_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 437.0
REGS2_k127_585127_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 383.0
REGS2_k127_585127_3 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000000006877 194.0
REGS2_k127_585127_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000001293 182.0
REGS2_k127_585127_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000008523 82.0
REGS2_k127_585127_6 - - - - 0.00006016 52.0
REGS2_k127_5866394_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1666.0
REGS2_k127_5866394_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.952e-296 919.0
REGS2_k127_5866394_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 572.0
REGS2_k127_5866394_3 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 475.0
REGS2_k127_5866394_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 437.0
REGS2_k127_5866394_5 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 336.0
REGS2_k127_5866394_6 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000002596 249.0
REGS2_k127_5866394_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000004082 93.0
REGS2_k127_5866394_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000001758 88.0
REGS2_k127_5884163_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.967e-229 745.0
REGS2_k127_5884163_1 Cupin 2, conserved barrel domain protein - - - 0.00000004045 55.0
REGS2_k127_5893276_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.37e-264 836.0
REGS2_k127_5893276_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
REGS2_k127_5893276_2 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001848 292.0
REGS2_k127_5893276_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001114 217.0
REGS2_k127_590880_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 1.304e-241 782.0
REGS2_k127_590880_1 Aldehyde dehydrogenase family - - - 1.126e-208 659.0
REGS2_k127_590880_2 lipid kinase activity - - - 0.0000000001623 62.0
REGS2_k127_5911488_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.324e-220 689.0
REGS2_k127_5911488_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 3.516e-202 638.0
REGS2_k127_5911488_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 529.0
REGS2_k127_5911488_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000133 170.0
REGS2_k127_5911488_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000005081 121.0
REGS2_k127_5929558_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 8.211e-208 652.0
REGS2_k127_5929558_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 391.0
REGS2_k127_5929558_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 381.0
REGS2_k127_5929558_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 329.0
REGS2_k127_5940221_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 419.0
REGS2_k127_5940221_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 399.0
REGS2_k127_5940221_2 Acetyltransferase (GNAT) domain - - - 0.000000389 53.0
REGS2_k127_5940221_3 Histidine kinase K20974 - 2.7.13.3 0.0006089 44.0
REGS2_k127_5943119_0 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 459.0
REGS2_k127_5943119_1 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000006961 127.0
REGS2_k127_5949992_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 509.0
REGS2_k127_5949992_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 376.0
REGS2_k127_5949992_2 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 383.0
REGS2_k127_5949992_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000001547 263.0
REGS2_k127_5949992_4 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000002102 218.0
REGS2_k127_5949992_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000003631 173.0
REGS2_k127_5949992_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000001259 85.0
REGS2_k127_596037_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.473e-197 621.0
REGS2_k127_596037_1 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000352 160.0
REGS2_k127_596037_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000004156 103.0
REGS2_k127_599154_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.145e-212 670.0
REGS2_k127_599154_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 485.0
REGS2_k127_599154_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 467.0
REGS2_k127_599154_3 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 414.0
REGS2_k127_599154_4 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000004085 205.0
REGS2_k127_599154_5 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0000000000000000000000001441 108.0
REGS2_k127_6039651_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1716.0
REGS2_k127_6039651_1 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 433.0
REGS2_k127_6052889_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 605.0
REGS2_k127_6052889_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 486.0
REGS2_k127_6052889_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
REGS2_k127_6052889_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000006128 96.0
REGS2_k127_6052889_4 isomerase activity K01821 - 5.3.2.6 0.000000000000005225 76.0
REGS2_k127_6076781_0 extracellular solute-binding protein, family 5 K02035 - - 1.308e-210 668.0
REGS2_k127_6076781_1 Belongs to the GSP D family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 502.0
REGS2_k127_6076781_2 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 386.0
REGS2_k127_6076781_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 383.0
REGS2_k127_6076781_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000579 137.0
REGS2_k127_6076781_5 - - - - 0.000000000000000000211 92.0
REGS2_k127_6077345_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.699e-285 883.0
REGS2_k127_6077345_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 392.0
REGS2_k127_6077345_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000001744 165.0
REGS2_k127_6077345_3 - - - - 0.0000000000000000000000000000002993 127.0
REGS2_k127_6077345_4 - - - - 0.0000009846 57.0
REGS2_k127_614278_0 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 412.0
REGS2_k127_614278_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 294.0
REGS2_k127_614278_2 - - - - 0.000000000000000000001151 104.0
REGS2_k127_6147750_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.433e-321 990.0
REGS2_k127_6158072_0 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 398.0
REGS2_k127_6158072_1 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.00000000000000000000000000000000000000000000981 171.0
REGS2_k127_6158072_2 ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000001769 157.0
REGS2_k127_6171228_0 BFD domain protein 2Fe-2S -binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001325 293.0
REGS2_k127_6171228_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000122 100.0
REGS2_k127_6193401_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 4.542e-202 645.0
REGS2_k127_6193401_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 340.0
REGS2_k127_6193401_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003517 253.0
REGS2_k127_6193401_3 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001393 255.0
REGS2_k127_6193401_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000001663 207.0
REGS2_k127_6193401_5 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000002171 196.0
REGS2_k127_6193401_6 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000007045 184.0
REGS2_k127_6205680_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 7.201e-223 696.0
REGS2_k127_6225641_0 PFAM natural resistance-associated macrophage protein - - - 6.674e-205 644.0
REGS2_k127_6225641_1 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 511.0
REGS2_k127_6225641_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
REGS2_k127_6225641_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000003992 188.0
REGS2_k127_6225641_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000001169 171.0
REGS2_k127_6225641_5 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000004321 170.0
REGS2_k127_6225641_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000000000000001728 184.0
REGS2_k127_623584_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000003933 246.0
REGS2_k127_623584_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000001829 218.0
REGS2_k127_623584_2 - - - - 0.000000000000000000000000000004044 125.0
REGS2_k127_6279342_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 427.0
REGS2_k127_6279342_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000001364 189.0
REGS2_k127_6299721_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 353.0
REGS2_k127_6304032_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 336.0
REGS2_k127_6309609_0 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 458.0
REGS2_k127_6309609_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
REGS2_k127_6309609_2 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 312.0
REGS2_k127_6309787_0 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003356 280.0
REGS2_k127_6309787_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000001822 162.0
REGS2_k127_6309787_2 - - - - 0.0000000000007863 71.0
REGS2_k127_634850_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 1.295e-204 649.0
REGS2_k127_634850_1 Aminotransferase, class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 370.0
REGS2_k127_634850_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 252.0
REGS2_k127_6379854_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1006.0
REGS2_k127_6379854_1 Domain of unknown function (DUF4118) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000286 299.0
REGS2_k127_6379854_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000001318 180.0
REGS2_k127_6379854_3 cheY-homologous receiver domain - - - 0.0000001722 53.0
REGS2_k127_640975_0 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 469.0
REGS2_k127_640975_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000273 265.0
REGS2_k127_640975_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000002361 209.0
REGS2_k127_6460652_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 8.109e-282 877.0
REGS2_k127_6460652_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 432.0
REGS2_k127_6476897_0 transmembrane transporter activity K03296,K07788,K07789 - - 2.013e-226 703.0
REGS2_k127_6476897_1 transmembrane transporter activity K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 541.0
REGS2_k127_6484889_0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000001498 162.0
REGS2_k127_6484889_1 - - - - 0.0000004761 55.0
REGS2_k127_6491208_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001336 260.0
REGS2_k127_6491208_1 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000001032 229.0
REGS2_k127_6491208_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000157 194.0
REGS2_k127_6515850_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 5.286e-242 758.0
REGS2_k127_6515850_1 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000001646 75.0
REGS2_k127_6516065_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
REGS2_k127_6516065_1 metallopeptidase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 264.0
REGS2_k127_6516065_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000001133 139.0
REGS2_k127_6523941_0 citrate CoA-transferase activity K01643 - 2.8.3.10 3.37e-280 867.0
REGS2_k127_6523941_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 585.0
REGS2_k127_6523941_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 465.0
REGS2_k127_6523941_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 445.0
REGS2_k127_6523941_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000002232 190.0
REGS2_k127_6523941_5 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000000000000000000000001564 146.0
REGS2_k127_6523941_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000005094 141.0
REGS2_k127_6573863_0 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002781 284.0
REGS2_k127_6573863_1 TonB dependent receptor K16087 - - 0.000000000000000000000000000002435 140.0
REGS2_k127_6591841_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000003036 204.0
REGS2_k127_6591841_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000004486 91.0
REGS2_k127_6591841_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.000000000000003281 76.0
REGS2_k127_6592897_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 597.0
REGS2_k127_6616775_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 387.0
REGS2_k127_6616775_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 370.0
REGS2_k127_6616775_2 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000004875 196.0
REGS2_k127_6616775_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000000000000000000000000000000000003238 147.0
REGS2_k127_6616775_4 - - - - 0.0000000000000007259 84.0
REGS2_k127_6622232_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.275e-293 910.0
REGS2_k127_6622232_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000001363 124.0
REGS2_k127_6622232_2 Belongs to the UPF0337 (CsbD) family - - - 0.0001351 46.0
REGS2_k127_6639728_0 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 501.0
REGS2_k127_6639728_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000006148 263.0
REGS2_k127_664235_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 281.0
REGS2_k127_664235_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000003016 211.0
REGS2_k127_664235_2 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000001782 106.0
REGS2_k127_664235_3 Sigma factor PP2C-like phosphatases - - - 0.00000009356 60.0
REGS2_k127_6646167_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.961e-313 965.0
REGS2_k127_6646167_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 373.0
REGS2_k127_6646167_2 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 280.0
REGS2_k127_6646167_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002107 250.0
REGS2_k127_6646167_4 diguanylate cyclase - - - 0.0000000004921 60.0
REGS2_k127_6649326_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 3.187e-264 824.0
REGS2_k127_665066_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 333.0
REGS2_k127_665066_2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 291.0
REGS2_k127_665066_3 - - - - 0.0000000000000000000000000000000000000000000000000001177 193.0
REGS2_k127_666078_0 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 302.0
REGS2_k127_6663491_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 567.0
REGS2_k127_6663491_1 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 499.0
REGS2_k127_6663491_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 389.0
REGS2_k127_6663491_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 323.0
REGS2_k127_6663491_4 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 272.0
REGS2_k127_6663491_5 phosphorelay signal transduction system - - - 0.000000000000000000000002759 118.0
REGS2_k127_6666100_0 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 402.0
REGS2_k127_6666100_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 353.0
REGS2_k127_6666100_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 293.0
REGS2_k127_6666100_3 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009673 252.0
REGS2_k127_6666100_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000003097 120.0
REGS2_k127_6693744_0 Transposase, Mutator family - - - 0.000000000005976 78.0
REGS2_k127_6698808_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000001537 177.0
REGS2_k127_6709105_0 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 2.752e-272 859.0
REGS2_k127_6709105_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007817 267.0
REGS2_k127_6709105_2 Belongs to the amidase family K01426 - 3.5.1.4 0.00000002535 55.0
REGS2_k127_6712167_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.0 1240.0
REGS2_k127_6712167_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
REGS2_k127_6712167_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000199 159.0
REGS2_k127_6716168_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 415.0
REGS2_k127_6716168_1 BioY family K03523 - - 0.00000000000000000000000000000000000000002531 157.0
REGS2_k127_6716168_2 - - - - 0.0000000000000000000000000001675 122.0
REGS2_k127_6716168_3 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.00000000000000000000000004986 118.0
REGS2_k127_6754900_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 8.187e-306 955.0
REGS2_k127_6754900_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 423.0
REGS2_k127_6754900_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 376.0
REGS2_k127_6754900_3 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005561 226.0
REGS2_k127_6754900_4 - - - - 0.00000000000000000000000000000000000000227 159.0
REGS2_k127_6754900_5 amino acid - - - 0.00000000006121 64.0
REGS2_k127_6754900_6 - - - - 0.0000001742 59.0
REGS2_k127_6755858_0 Histidine kinase - - - 0.0 1285.0
REGS2_k127_6755858_1 response regulator, receiver - - - 6.121e-213 670.0
REGS2_k127_6755858_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000001748 211.0
REGS2_k127_6755858_3 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000002846 183.0
REGS2_k127_6762063_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 590.0
REGS2_k127_6762063_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 430.0
REGS2_k127_6762063_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 421.0
REGS2_k127_6762063_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 316.0
REGS2_k127_680945_0 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002561 282.0
REGS2_k127_680945_1 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000008695 178.0
REGS2_k127_680945_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000007125 121.0
REGS2_k127_6813374_0 transposase activity - - - 0.00000000000000000000000000000000001024 153.0
REGS2_k127_6813374_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000001145 136.0
REGS2_k127_6821155_0 Beta-Casp domain K07576 - - 4.679e-236 742.0
REGS2_k127_6821155_1 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 516.0
REGS2_k127_6838549_0 Protein of unknown function (DUF1800) - - - 5.038e-195 630.0
REGS2_k127_6838549_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 475.0
REGS2_k127_6838549_2 COG3209 Rhs family protein - - - 0.00000000000001071 89.0
REGS2_k127_6844534_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 1.447e-246 783.0
REGS2_k127_6844534_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000000000000000000000001386 106.0
REGS2_k127_6855525_0 His Kinase A (phosphoacceptor) domain - - - 3.724e-200 637.0
REGS2_k127_6855525_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0002223 43.0
REGS2_k127_6860778_0 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000004221 200.0
REGS2_k127_6860778_1 Cold shock protein K03704 - - 0.000000000000000000000000001262 116.0
REGS2_k127_6860778_2 Domain of unknown function (DUF2520) - - - 0.000000000000000000001563 99.0
REGS2_k127_6860778_3 DNA polymerase X family K02347 - - 0.00000000000006507 74.0
REGS2_k127_6863305_0 Histidine kinase K07636 - 2.7.13.3 2.979e-197 634.0
REGS2_k127_6863305_1 alpha beta alpha domain I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 607.0
REGS2_k127_6863305_2 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 592.0
REGS2_k127_6863305_3 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 504.0
REGS2_k127_6863305_4 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 477.0
REGS2_k127_6863305_5 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 372.0
REGS2_k127_6863305_6 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 362.0
REGS2_k127_6863305_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 337.0
REGS2_k127_6863305_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000008209 224.0
REGS2_k127_6863305_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000001293 128.0
REGS2_k127_6902924_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
REGS2_k127_6902924_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000000000000000000000000000000002644 178.0
REGS2_k127_6902924_2 Transposase - - - 0.0000000000000000000000002627 111.0
REGS2_k127_6902924_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000001257 82.0
REGS2_k127_6908318_0 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000002619 219.0
REGS2_k127_6908318_1 - - - - 0.00000000000000000000000000000000000000003452 162.0
REGS2_k127_6908318_2 - - - - 0.000000000000000000000000000000607 128.0
REGS2_k127_6908318_3 Pilus assembly protein K02662 - - 0.000000000000000000000000000002864 127.0
REGS2_k127_6908318_4 - K02664 - - 0.000000000000000000000002894 109.0
REGS2_k127_6908318_5 Belongs to the HesB IscA family - - - 0.000000000000000000000004755 101.0
REGS2_k127_6945114_0 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000965 117.0
REGS2_k127_6945114_1 UTRA K03710 - - 0.000000000001702 73.0
REGS2_k127_6962814_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 507.0
REGS2_k127_6962814_1 slime layer polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 435.0
REGS2_k127_6962814_2 Male sterility protein K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 332.0
REGS2_k127_6962814_3 AMP-binding enzyme K01897 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044464,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:1901576 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000006649 228.0
REGS2_k127_6962814_4 Male sterility protein - - - 0.000000000000000000000000000000000001919 152.0
REGS2_k127_696285_0 GGDEF domain - - - 8.394e-309 970.0
REGS2_k127_696285_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 476.0
REGS2_k127_696285_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 462.0
REGS2_k127_696285_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 374.0
REGS2_k127_696285_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 312.0
REGS2_k127_696285_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000008229 181.0
REGS2_k127_696285_6 - - - - 0.00000000000000000000000000000000000000000004274 177.0
REGS2_k127_696285_7 - - - - 0.000000002554 60.0
REGS2_k127_6965191_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 479.0
REGS2_k127_6965191_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000007331 220.0
REGS2_k127_6965191_2 - - - - 0.00000000000007176 77.0
REGS2_k127_6968409_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 420.0
REGS2_k127_6968409_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 407.0
REGS2_k127_6968409_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000008611 235.0
REGS2_k127_6968409_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000001339 237.0
REGS2_k127_6968409_4 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000001132 153.0
REGS2_k127_7022906_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1078.0
REGS2_k127_7022906_1 surface antigen variable number - - - 8.326e-299 952.0
REGS2_k127_7022906_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 308.0
REGS2_k127_7022906_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000005039 246.0
REGS2_k127_7022906_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000007301 158.0
REGS2_k127_7022906_5 MoeZ MoeB K21029 - 2.7.7.80 0.0000000000000000000000003721 106.0
REGS2_k127_7054449_0 ZIP Zinc transporter K07238,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 356.0
REGS2_k127_7054449_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 299.0
REGS2_k127_7054449_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 292.0
REGS2_k127_7069095_0 3-demethylubiquinone-9 3-O-methyltransferase activity K15257,K18534 - 2.1.1.295 0.000000000000000000000000000000000000000000000000000000124 204.0
REGS2_k127_7069095_1 - - - - 0.0000000000000000000000000000000000000000000000002722 190.0
REGS2_k127_7069095_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000001155 56.0
REGS2_k127_7076041_0 ABC transporter, transmembrane K18890 - - 3.341e-291 904.0
REGS2_k127_7076041_1 Peptidase family M1 domain - - - 9.71e-263 826.0
REGS2_k127_7076041_10 hemerythrin HHE cation binding domain - - - 0.0000000000000000002057 94.0
REGS2_k127_7076041_11 - - - - 0.00000000000003038 74.0
REGS2_k127_7076041_2 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 2.838e-203 644.0
REGS2_k127_7076041_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 536.0
REGS2_k127_7076041_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 517.0
REGS2_k127_7076041_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 439.0
REGS2_k127_7076041_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 423.0
REGS2_k127_7076041_7 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 335.0
REGS2_k127_7076041_8 - - - - 0.0000000000000000000000000000000000000006334 161.0
REGS2_k127_7076041_9 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000005507 139.0
REGS2_k127_7083991_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 531.0
REGS2_k127_7083991_1 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 346.0
REGS2_k127_7083991_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
REGS2_k127_7083991_3 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 294.0
REGS2_k127_7110173_0 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 609.0
REGS2_k127_7110173_1 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 591.0
REGS2_k127_7110173_2 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 400.0
REGS2_k127_7110173_3 Ribosomal subunit interface protein K05808 - - 0.00000000000000000000000000292 117.0
REGS2_k127_7118685_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 610.0
REGS2_k127_7130132_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1107.0
REGS2_k127_7130132_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 486.0
REGS2_k127_7130132_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 459.0
REGS2_k127_7130132_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 410.0
REGS2_k127_7130132_4 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 390.0
REGS2_k127_7130132_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000854 282.0
REGS2_k127_7130132_6 - - - - 0.0000000000000000000000000000000000000000000000000003628 206.0
REGS2_k127_7130132_7 Belongs to the PstS family K02040 - - 0.00000000002385 64.0
REGS2_k127_7140772_0 - - - - 0.0000000000000000000000000000000000000000000000000000002318 210.0
REGS2_k127_7140772_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000004597 145.0
REGS2_k127_7140772_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000008575 115.0
REGS2_k127_7147924_0 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 388.0
REGS2_k127_7147924_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 295.0
REGS2_k127_7147924_2 Regulatory protein, FmdB family - - - 0.00000000000009588 72.0
REGS2_k127_7147986_0 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
REGS2_k127_7147986_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000005035 212.0
REGS2_k127_7147986_2 - - - - 0.000000000000000000000000000003975 132.0
REGS2_k127_7168068_0 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000009154 226.0
REGS2_k127_7168068_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000002964 89.0
REGS2_k127_7179163_0 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 367.0
REGS2_k127_7179163_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000005618 108.0
REGS2_k127_7179163_2 zinc-ribbon domain - - - 0.0000000000000001558 85.0
REGS2_k127_7183995_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1278.0
REGS2_k127_7183995_1 3-demethylubiquinone-9 3-O-methyltransferase activity K16328 - 2.7.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 305.0
REGS2_k127_7183995_2 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000003733 206.0
REGS2_k127_7183995_3 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000159 181.0
REGS2_k127_7183995_4 - - - - 0.0000000000000000000000000000000000002309 149.0
REGS2_k127_7183995_5 Bacterial DNA-binding protein K03530 - - 0.0000000000000000000000000000000000461 136.0
REGS2_k127_7183995_6 membrane transporter protein K07090 - - 0.0000000000000000000000000005334 115.0
REGS2_k127_720035_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 457.0
REGS2_k127_720035_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 415.0
REGS2_k127_720035_2 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 344.0
REGS2_k127_720035_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 301.0
REGS2_k127_720035_4 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
REGS2_k127_720035_5 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
REGS2_k127_720035_6 PFAM NifU-like N terminal domain K04488 - - 0.000000000000000000000000002125 115.0
REGS2_k127_720035_7 - - - - 0.00004741 51.0
REGS2_k127_7203572_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 2.24e-281 883.0
REGS2_k127_7203572_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 473.0
REGS2_k127_7203572_2 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 448.0
REGS2_k127_7203572_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
REGS2_k127_7203572_4 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000009021 110.0
REGS2_k127_7203572_5 sequence-specific DNA binding - - - 0.0000000006118 65.0
REGS2_k127_7203572_6 ubiE/COQ5 methyltransferase family - - - 0.0000000665 62.0
REGS2_k127_7216453_0 HELICc2 K03722 - 3.6.4.12 5.42e-290 900.0
REGS2_k127_7216453_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 360.0
REGS2_k127_7216453_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 312.0
REGS2_k127_7216453_3 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000001692 207.0
REGS2_k127_7217518_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 426.0
REGS2_k127_7217518_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 346.0
REGS2_k127_7217518_2 Transmembrane secretion effector - - - 0.000000000000000007957 85.0
REGS2_k127_7222292_0 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 361.0
REGS2_k127_7222292_1 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000001188 250.0
REGS2_k127_7222292_2 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000005067 213.0
REGS2_k127_7284415_0 PFAM peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 466.0
REGS2_k127_7284415_1 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000008938 211.0
REGS2_k127_728636_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004058 259.0
REGS2_k127_728636_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000008481 212.0
REGS2_k127_7293636_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 333.0
REGS2_k127_7293636_1 - - - - 0.00000000000000000000000000000000000000000000000000000000108 206.0
REGS2_k127_7300830_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 368.0
REGS2_k127_7300830_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003451 257.0
REGS2_k127_7303529_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 445.0
REGS2_k127_7303529_1 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 326.0
REGS2_k127_7303529_2 2 iron, 2 sulfur cluster binding K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 321.0
REGS2_k127_7303529_3 - - - - 0.0000000000000000000000000000000000000000005761 162.0
REGS2_k127_7303529_4 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.000000000000000000000000000000000000000004048 171.0
REGS2_k127_7305626_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 503.0
REGS2_k127_7305626_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000518 266.0
REGS2_k127_7311511_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000193 239.0
REGS2_k127_7311511_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000001103 184.0
REGS2_k127_7311511_2 DoxX K15977 - - 0.0000000000000000000000000000000000000000000004335 172.0
REGS2_k127_731212_0 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 1.079e-283 901.0
REGS2_k127_731212_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001796 288.0
REGS2_k127_731212_2 transferase activity, transferring hexosyl groups K15897 - 3.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000003605 240.0
REGS2_k127_7319465_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 594.0
REGS2_k127_7319465_1 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 420.0
REGS2_k127_7319465_2 methyltransferase - - - 0.00000000001645 68.0
REGS2_k127_7332080_0 Belongs to the GSP D family K02453 - - 3.594e-272 860.0
REGS2_k127_7332080_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
REGS2_k127_7332080_2 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000003645 241.0
REGS2_k127_7332080_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000002931 248.0
REGS2_k127_7332080_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000001538 174.0
REGS2_k127_7340241_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 560.0
REGS2_k127_7340241_1 Histidine kinase K02668,K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 413.0
REGS2_k127_7340241_2 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 307.0
REGS2_k127_7340241_3 Glycosyl transferase, family 2 - - - 0.00000000000000001965 85.0
REGS2_k127_7341363_0 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 357.0
REGS2_k127_7341363_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000003607 193.0
REGS2_k127_7342766_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
REGS2_k127_7342766_1 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 321.0
REGS2_k127_7346010_0 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000003057 160.0
REGS2_k127_7346010_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000003786 125.0
REGS2_k127_7346010_2 - - - - 0.0000000000000000000000000004081 122.0
REGS2_k127_7373992_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 377.0
REGS2_k127_7373992_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000003207 164.0
REGS2_k127_7373992_2 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000003176 156.0
REGS2_k127_7373992_3 - - - - 0.0000000000000000000000000000000125 142.0
REGS2_k127_7373992_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000009715 85.0
REGS2_k127_7373992_5 Redoxin K03564 - 1.11.1.15 0.000000000001687 67.0
REGS2_k127_7380451_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 1.919e-222 706.0
REGS2_k127_7380451_1 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 362.0
REGS2_k127_7380451_2 PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000003268 180.0
REGS2_k127_7380451_3 - - - - 0.00000000000000000000000000001118 125.0
REGS2_k127_7380451_4 haloacid dehalogenase K01560 - 3.8.1.2 0.0002902 47.0
REGS2_k127_7380451_5 Serine aminopeptidase, S33 - - - 0.0008363 50.0
REGS2_k127_7385596_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 336.0
REGS2_k127_7385596_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 304.0
REGS2_k127_7385596_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
REGS2_k127_7385596_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006578 267.0
REGS2_k127_7385596_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006688 275.0
REGS2_k127_7385596_5 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003786 229.0
REGS2_k127_7385596_6 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000001895 200.0
REGS2_k127_7385596_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000535 158.0
REGS2_k127_7385596_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000007198 146.0
REGS2_k127_7385596_9 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000005438 91.0
REGS2_k127_7401883_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 464.0
REGS2_k127_7401883_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
REGS2_k127_7401883_2 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000005989 147.0
REGS2_k127_7401883_3 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000001124 63.0
REGS2_k127_7411293_0 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 391.0
REGS2_k127_7411293_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000008762 167.0
REGS2_k127_7411293_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000004314 132.0
REGS2_k127_7411661_0 Glutamate synthase central domain K00265 - 1.4.1.13,1.4.1.14 2.913e-270 857.0
REGS2_k127_7427587_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 5.885e-223 704.0
REGS2_k127_7427587_1 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 289.0
REGS2_k127_7427587_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004894 239.0
REGS2_k127_7441001_0 PFAM peptidase K16922 - - 0.0000000000000000000000000000000000000000000000006797 199.0
REGS2_k127_7441001_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000000000000000000005938 193.0
REGS2_k127_7441001_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000009397 111.0
REGS2_k127_7441001_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000001563 98.0
REGS2_k127_7441001_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000001054 84.0
REGS2_k127_7465699_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 400.0
REGS2_k127_7465699_1 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 396.0
REGS2_k127_7465699_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 347.0
REGS2_k127_7465699_3 aminopeptidase N - - - 0.0001024 46.0
REGS2_k127_7465699_4 Belongs to the UPF0337 (CsbD) family - - - 0.0002743 47.0
REGS2_k127_751963_0 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 9.393e-198 622.0
REGS2_k127_751963_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 293.0
REGS2_k127_751963_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000601 117.0
REGS2_k127_751963_3 PilZ domain - - - 0.0000000000000000000003485 100.0
REGS2_k127_752422_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.874e-210 658.0
REGS2_k127_752422_1 Amidohydrolase family - - - 4.042e-196 619.0
REGS2_k127_752422_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 565.0
REGS2_k127_752422_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000000000476 216.0
REGS2_k127_752422_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000002399 141.0
REGS2_k127_7543916_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.669e-247 771.0
REGS2_k127_7543916_1 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
REGS2_k127_7543916_2 - - - - 0.00000000000000000000000000000000000000000000003638 177.0
REGS2_k127_7543916_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000003418 124.0
REGS2_k127_7543916_4 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000122 115.0
REGS2_k127_7543916_5 Bacterial regulatory protein, Fis family - - - 0.000000000197 61.0
REGS2_k127_7549798_0 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 521.0
REGS2_k127_7559301_0 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000006879 189.0
REGS2_k127_7559301_1 Cytochrome c K02305 - - 0.00000000000000000000000000000001559 135.0
REGS2_k127_7559301_2 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000009153 123.0
REGS2_k127_7578369_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 464.0
REGS2_k127_7578369_1 PFAM von Willebrand factor type A - - - 0.00000000001598 73.0
REGS2_k127_7582497_0 diguanylate cyclase K02030,K06950,K16923 - - 3.435e-235 737.0
REGS2_k127_7595252_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.174e-303 944.0
REGS2_k127_760377_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 2.296e-196 627.0
REGS2_k127_7638916_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 393.0
REGS2_k127_7638916_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 311.0
REGS2_k127_7638916_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000078 239.0
REGS2_k127_7638916_3 PspC domain K03973 - - 0.0000000000000000000000000000000005825 134.0
REGS2_k127_7659744_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 375.0
REGS2_k127_7659744_1 sptr putative - - - 0.0000000000000000002123 91.0
REGS2_k127_7664680_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 598.0
REGS2_k127_7664680_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000008423 255.0
REGS2_k127_7664680_2 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000002032 186.0
REGS2_k127_7670326_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 436.0
REGS2_k127_7670326_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000006536 199.0
REGS2_k127_7688477_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 7.706e-209 660.0
REGS2_k127_7688477_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.713e-194 613.0
REGS2_k127_7688477_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 550.0
REGS2_k127_7688477_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 435.0
REGS2_k127_7690728_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.12e-303 941.0
REGS2_k127_7690728_1 peroxiredoxin, OsmC subfamily K04063 - - 0.0000000000000000000000000000000000000000000000000000000004881 206.0
REGS2_k127_7690728_2 Protein of unknown function (DUF1761) - - - 0.0000000000000000000000000000000001123 145.0
REGS2_k127_7690728_3 - - - - 0.00000000000000000000000001162 115.0
REGS2_k127_7690728_4 - - - - 0.00000000000000002311 93.0
REGS2_k127_7736004_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.959e-291 904.0
REGS2_k127_7736004_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 339.0
REGS2_k127_7736004_2 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000009958 213.0
REGS2_k127_7736004_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000012 139.0
REGS2_k127_7736004_4 Regulatory protein, FmdB - - - 0.000000000000000000000001992 109.0
REGS2_k127_7754188_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 415.0
REGS2_k127_7754188_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 317.0
REGS2_k127_7754188_2 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 300.0
REGS2_k127_7754188_3 - - - - 0.00000000009468 68.0
REGS2_k127_7754188_4 cytochrome c - - - 0.0009163 43.0
REGS2_k127_7760548_0 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 313.0
REGS2_k127_7760548_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000587 246.0
REGS2_k127_7760548_2 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000001751 93.0
REGS2_k127_7765505_0 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004911 280.0
REGS2_k127_7765505_1 DinB superfamily - - - 0.00000000000000000000000000000004364 133.0
REGS2_k127_7765505_2 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000004804 100.0
REGS2_k127_7778957_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 497.0
REGS2_k127_7778957_1 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000000000000000002197 193.0
REGS2_k127_7778957_2 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000002633 156.0
REGS2_k127_7819778_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 507.0
REGS2_k127_7819778_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 488.0
REGS2_k127_7819778_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000008514 52.0
REGS2_k127_7820916_0 PFAM Response regulator receiver domain K07713 - - 5.248e-242 754.0
REGS2_k127_7820916_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002341 258.0
REGS2_k127_7820916_2 cyclic nucleotide-binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000001811 204.0
REGS2_k127_7820916_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001209 160.0
REGS2_k127_7820916_6 alpha-L-arabinofuranosidase - - - 0.0002045 45.0
REGS2_k127_7821535_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.006e-312 965.0
REGS2_k127_7821535_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001543 267.0
REGS2_k127_782447_0 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 543.0
REGS2_k127_782447_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 545.0
REGS2_k127_783746_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 447.0
REGS2_k127_783746_1 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 272.0
REGS2_k127_7847950_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.043e-266 826.0
REGS2_k127_7847950_1 Membrane - - - 0.000000000005184 71.0
REGS2_k127_7848065_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 325.0
REGS2_k127_7848065_1 LemA family K03744 - - 0.00000000000000008147 81.0
REGS2_k127_7857423_0 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 460.0
REGS2_k127_7860957_0 diguanylate cyclase K02030,K06950,K16923 - - 0.0 1147.0
REGS2_k127_7860957_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.379e-234 733.0
REGS2_k127_7860957_2 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 462.0
REGS2_k127_7879832_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 8.541e-236 747.0
REGS2_k127_7879832_1 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 503.0
REGS2_k127_7879832_2 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000004817 220.0
REGS2_k127_7879832_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000156 161.0
REGS2_k127_7879832_4 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000003879 109.0
REGS2_k127_7880680_0 Heat shock 70 kDa protein K04043 - - 5.336e-249 773.0
REGS2_k127_7905406_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 506.0
REGS2_k127_7905406_1 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 386.0
REGS2_k127_7905406_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000001411 233.0
REGS2_k127_7905406_3 - - - - 0.00000000000000000002463 92.0
REGS2_k127_7905406_4 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000003806 91.0
REGS2_k127_7911971_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 529.0
REGS2_k127_7911971_1 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 317.0
REGS2_k127_7911971_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007948 280.0
REGS2_k127_7911971_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000002916 182.0
REGS2_k127_7918279_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003961 273.0
REGS2_k127_7918279_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000009238 177.0
REGS2_k127_7929598_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 555.0
REGS2_k127_7929598_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 514.0
REGS2_k127_7929598_10 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000008344 168.0
REGS2_k127_7929598_11 Prokaryotic N-terminal methylation motif K02650,K02679,K10926,K12285 - - 0.00000000000000000000000000000001173 137.0
REGS2_k127_7929598_12 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000002812 124.0
REGS2_k127_7929598_13 Ribosomal L32p protein family K02911 - - 0.0000000000000000000000004099 107.0
REGS2_k127_7929598_14 DNA-templated transcription, initiation K03088 - - 0.0000000000000859 74.0
REGS2_k127_7929598_15 RDD domain containing protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000006894 55.0
REGS2_k127_7929598_16 Photosynthesis system II assembly factor YCF48 - - - 0.0005414 52.0
REGS2_k127_7929598_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 499.0
REGS2_k127_7929598_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 467.0
REGS2_k127_7929598_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 454.0
REGS2_k127_7929598_5 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 340.0
REGS2_k127_7929598_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 339.0
REGS2_k127_7929598_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000004375 210.0
REGS2_k127_7929598_8 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000000000000000000000000004125 203.0
REGS2_k127_7929598_9 - - - - 0.0000000000000000000000000000000000000000000000001963 182.0
REGS2_k127_7935359_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1369.0
REGS2_k127_7935359_1 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 629.0
REGS2_k127_7935359_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000191 189.0
REGS2_k127_7935359_3 nuclear chromosome segregation - - - 0.00000000000000000000001102 104.0
REGS2_k127_7959742_0 Transcriptional regulator, arsR family - - - 0.0000000000000000000000000000000239 126.0
REGS2_k127_7959742_1 transposase activity - - - 0.000000004017 68.0
REGS2_k127_7962446_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.0 1049.0
REGS2_k127_7962446_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 349.0
REGS2_k127_7962446_2 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 319.0
REGS2_k127_7962446_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006633 245.0
REGS2_k127_7962446_4 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
REGS2_k127_7962446_5 PFAM Redoxin - - - 0.000000000000000000000000000000000000000000000000000004778 201.0
REGS2_k127_7962446_6 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000001288 182.0
REGS2_k127_7962446_7 - - - - 0.000000000000000000000001309 105.0
REGS2_k127_7962446_8 - - - - 0.000001995 50.0
REGS2_k127_797603_0 AMP-binding enzyme K01897 - 6.2.1.3 3.068e-224 715.0
REGS2_k127_797603_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 434.0
REGS2_k127_797603_2 - - - - 0.000000000000000000001492 98.0
REGS2_k127_797603_3 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000001456 57.0
REGS2_k127_797603_4 peroxiredoxin activity K03564 - 1.11.1.15 0.000000499 52.0
REGS2_k127_8013558_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
REGS2_k127_8013558_1 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000000002254 192.0
REGS2_k127_8013558_2 - - - - 0.000000000000000000000000000000002829 130.0
REGS2_k127_8013558_3 - - - - 0.0000003775 54.0
REGS2_k127_8049609_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 406.0
REGS2_k127_8049609_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000005796 107.0
REGS2_k127_8051215_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005634 257.0
REGS2_k127_8051215_1 cheY-homologous receiver domain - - - 0.000000000000000000000003244 107.0
REGS2_k127_8058169_0 Belongs to the DegT DnrJ EryC1 family K18653 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 402.0
REGS2_k127_8058169_1 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000001213 200.0
REGS2_k127_8075385_0 Belongs to the ClpA ClpB family K03696 - - 0.0 998.0
REGS2_k127_8075385_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000005851 150.0
REGS2_k127_8076713_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 531.0
REGS2_k127_8076713_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 317.0
REGS2_k127_8076713_2 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
REGS2_k127_8076713_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000001138 154.0
REGS2_k127_8076713_4 - - - - 0.00000005565 55.0
REGS2_k127_8076713_5 PD-(D/E)XK endonuclease - - - 0.000004552 54.0
REGS2_k127_8077946_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003628 275.0
REGS2_k127_8077946_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000001132 209.0
REGS2_k127_8083746_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 470.0
REGS2_k127_8083746_1 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007819 263.0
REGS2_k127_8086519_0 Rieske (2Fe-2S) iron-sulfur domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 514.0
REGS2_k127_8086519_1 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000001526 141.0
REGS2_k127_8086519_2 - - - - 0.000000000000000000000000003322 124.0
REGS2_k127_8096090_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 503.0
REGS2_k127_8096090_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 350.0
REGS2_k127_8096090_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000002209 121.0
REGS2_k127_8096090_4 MoeZ MoeB K21029 - 2.7.7.80 0.0000000000000000000000000212 108.0
REGS2_k127_8096090_6 - - - - 0.000002203 59.0
REGS2_k127_8099970_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 396.0
REGS2_k127_8099970_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 322.0
REGS2_k127_8099970_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000002402 175.0
REGS2_k127_8102233_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.323e-205 646.0
REGS2_k127_8102233_1 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 376.0
REGS2_k127_8122309_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 411.0
REGS2_k127_8122309_1 Male sterility protein K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004889 283.0
REGS2_k127_8122309_2 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000001367 180.0
REGS2_k127_8122309_3 - - - - 0.0000000000000000000005793 100.0
REGS2_k127_8122309_4 Phosphopantetheine attachment site K02078 - - 0.0000004037 55.0
REGS2_k127_8140594_0 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 504.0
REGS2_k127_8140594_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000000004735 169.0
REGS2_k127_8149404_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 389.0
REGS2_k127_8149404_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 304.0
REGS2_k127_8149404_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 303.0
REGS2_k127_8154110_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000009653 207.0
REGS2_k127_8154483_0 Bacterial regulatory protein, Fis family K07713 - - 8.598e-215 675.0
REGS2_k127_8154483_1 - - - - 0.00000000000000000000129 102.0
REGS2_k127_8154483_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000001542 72.0
REGS2_k127_8176338_0 Enterochelin esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 419.0
REGS2_k127_8176338_1 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 355.0
REGS2_k127_8176338_2 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
REGS2_k127_8176338_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
REGS2_k127_8176338_4 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
REGS2_k127_8176338_5 - - - - 0.000000001351 61.0
REGS2_k127_8193232_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 306.0
REGS2_k127_8193232_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000002179 216.0
REGS2_k127_8193240_0 Amino acid permease - - - 1.925e-304 951.0
REGS2_k127_8193240_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 457.0
REGS2_k127_8193240_2 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000004223 112.0
REGS2_k127_8196898_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 303.0
REGS2_k127_8196898_1 Proline dehydrogenase K00318 - - 0.00000000000000000006856 91.0
REGS2_k127_8196898_2 PEGA domain - - - 0.000408 52.0
REGS2_k127_82210_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 502.0
REGS2_k127_8231737_0 PFAM Short-chain dehydrogenase reductase SDR K00059,K03793 - 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 288.0
REGS2_k127_8231737_1 Transketolase, pyrimidine binding domain K00162,K00167,K21417 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 269.0
REGS2_k127_8231737_2 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000002838 214.0
REGS2_k127_8231737_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000005874 104.0
REGS2_k127_8231737_4 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001573 67.0
REGS2_k127_8249375_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 492.0
REGS2_k127_8249375_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000157 225.0
REGS2_k127_8249375_2 - - - - 0.00000000000000000000000000000000000000000000000000002789 196.0
REGS2_k127_8250018_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.374e-251 783.0
REGS2_k127_8263420_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000005353 180.0
REGS2_k127_8263420_1 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000009887 169.0
REGS2_k127_8263420_2 ATP-grasp - - - 0.0000000000000000000000000005753 122.0
REGS2_k127_8263420_3 O-Antigen ligase - - - 0.0003547 46.0
REGS2_k127_8265191_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 514.0
REGS2_k127_8265191_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 438.0
REGS2_k127_8265191_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 327.0
REGS2_k127_8265191_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000002453 235.0
REGS2_k127_8265191_4 Belongs to the P(II) protein family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000004861 243.0
REGS2_k127_8265191_5 - - - - 0.000000000000000000000000000000001635 133.0
REGS2_k127_8266001_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 5.443e-233 729.0
REGS2_k127_8266001_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 330.0
REGS2_k127_8266001_2 Domain of unknown function DUF302 - - - 0.00000000000000000000004844 103.0
REGS2_k127_8266001_3 Oxidoreductase molybdopterin binding domain - - - 0.00000001019 57.0
REGS2_k127_8281320_0 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 543.0
REGS2_k127_8285203_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 477.0
REGS2_k127_8285203_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 321.0
REGS2_k127_8285203_2 GlcNAc-PI de-N-acetylase K22135 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 284.0
REGS2_k127_8285203_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000007888 267.0
REGS2_k127_8285203_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000006451 172.0
REGS2_k127_8285203_5 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000001295 123.0
REGS2_k127_8285203_6 - - - - 0.00000000004487 66.0
REGS2_k127_8296004_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000001067 213.0
REGS2_k127_8296004_1 alpha, beta K06889 - - 0.00000002101 59.0
REGS2_k127_829848_0 Flotillin K07192 - - 2.518e-227 712.0
REGS2_k127_829848_1 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002432 269.0
REGS2_k127_829848_2 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
REGS2_k127_8301054_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 593.0
REGS2_k127_8301054_1 Histidine kinase K02482,K03557 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 553.0
REGS2_k127_8309318_0 Sodium:solute symporter family - - - 2.108e-301 932.0
REGS2_k127_8321565_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1165.0
REGS2_k127_8321565_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
REGS2_k127_8321565_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000001972 172.0
REGS2_k127_8321565_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000001457 165.0
REGS2_k127_8321565_4 response to heat K07090 - - 0.0000000000000000000000000000000007151 136.0
REGS2_k127_8345829_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 4.448e-220 694.0
REGS2_k127_8345829_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
REGS2_k127_8345829_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000003448 177.0
REGS2_k127_8345829_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000003189 127.0
REGS2_k127_8345829_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000002597 111.0
REGS2_k127_8356472_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 4.325e-198 625.0
REGS2_k127_8356472_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000389 197.0
REGS2_k127_8361826_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.86e-237 739.0
REGS2_k127_8361826_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 296.0
REGS2_k127_8361826_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000127 152.0
REGS2_k127_8361826_3 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000002774 139.0
REGS2_k127_8439320_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 575.0
REGS2_k127_8439320_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 365.0
REGS2_k127_8439320_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
REGS2_k127_8439320_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000007919 71.0
REGS2_k127_8439320_4 Bacterial protein of unknown function (DUF885) - - - 0.0000003193 53.0
REGS2_k127_8444373_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000786 145.0
REGS2_k127_8444373_1 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00003142 56.0
REGS2_k127_8482716_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 309.0
REGS2_k127_8482716_1 transcriptional regulator - - - 0.000000000000000000000000000000000000002682 155.0
REGS2_k127_8506191_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003385 274.0
REGS2_k127_8506191_1 Putative zinc-finger - - - 0.000000000000000000000000000000000000000000005735 171.0
REGS2_k127_8506191_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000006652 153.0
REGS2_k127_8526449_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
REGS2_k127_8526449_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 319.0
REGS2_k127_8526449_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000003761 55.0
REGS2_k127_853625_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 299.0
REGS2_k127_853625_1 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008315 293.0
REGS2_k127_853625_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000891 263.0
REGS2_k127_853625_3 NAD dependent epimerase/dehydratase family K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000008157 237.0
REGS2_k127_853625_4 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000003357 201.0
REGS2_k127_853625_5 Peptidase M16 inactive domain K07263 - - 0.000000000000000000002525 96.0
REGS2_k127_853625_6 Radical SAM - - - 0.000006058 51.0
REGS2_k127_8564207_0 Insulinase (Peptidase family M16) - - - 9.099e-216 683.0
REGS2_k127_8564207_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 404.0
REGS2_k127_8564207_2 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 404.0
REGS2_k127_8564207_3 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 340.0
REGS2_k127_877233_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 386.0
REGS2_k127_877233_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000001452 204.0
REGS2_k127_877233_2 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000004441 119.0
REGS2_k127_901726_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1141.0
REGS2_k127_901726_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00001305 58.0
REGS2_k127_905092_0 - - - - 0.00000000000000009472 91.0
REGS2_k127_905092_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000001271 87.0
REGS2_k127_91258_0 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 482.0
REGS2_k127_91258_1 Homocysteine K00547,K21169 - 2.1.1.10 0.00000000000000000000000000000000000000000006507 172.0
REGS2_k127_91258_2 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000236 170.0
REGS2_k127_91258_3 sequence-specific DNA binding - - - 0.0001758 50.0
REGS2_k127_91258_4 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0009163 43.0
REGS2_k127_934662_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000001103 175.0
REGS2_k127_945936_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 5.983e-302 946.0
REGS2_k127_945936_1 Beta-eliminating lyase K01667 - 4.1.99.1 5.435e-246 764.0
REGS2_k127_945936_2 Zinc carboxypeptidase K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 594.0
REGS2_k127_945936_3 Formate dehydrogenase N, transmembrane K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 399.0
REGS2_k127_945936_4 Cytochrome b/b6/petB K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 264.0
REGS2_k127_945936_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000153 250.0
REGS2_k127_945936_6 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000000000000000000000000143 189.0