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Overview

ID MAG03328
Name REGS2_bin.16
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus
Species
Assembly information
Completeness (%) 65.85
Contamination (%) 1.02
GC content (%) 56.0
N50 (bp) 6,949
Genome size (bp) 1,602,270

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1723

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1013901_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 1.373e-214 672.0
REGS2_k127_1013901_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
REGS2_k127_1018722_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.191e-319 990.0
REGS2_k127_1018722_1 PFAM ATP-binding region ATPase domain protein - - - 4.359e-227 718.0
REGS2_k127_1018722_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 292.0
REGS2_k127_1018722_3 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000002826 122.0
REGS2_k127_1080256_0 B12 binding domain - - - 8.246e-315 967.0
REGS2_k127_1080256_1 Sodium/hydrogen exchanger family - - - 2.276e-216 676.0
REGS2_k127_1080256_2 fad dependent oxidoreductase - - - 6.276e-200 631.0
REGS2_k127_1080256_3 Glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 426.0
REGS2_k127_1080256_4 pteridine-dependent deoxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 398.0
REGS2_k127_1080256_5 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 368.0
REGS2_k127_1080256_6 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 368.0
REGS2_k127_1080256_7 polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 311.0
REGS2_k127_1080256_8 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002508 270.0
REGS2_k127_1080256_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000002696 99.0
REGS2_k127_1082425_0 RNB K01147 - 3.1.13.1 2.17e-322 994.0
REGS2_k127_1082425_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 518.0
REGS2_k127_1082425_2 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 381.0
REGS2_k127_1082425_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
REGS2_k127_1082425_4 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000001124 107.0
REGS2_k127_1082425_5 EF-hand, calcium binding motif - - - 0.0000000000001991 78.0
REGS2_k127_1082425_6 - - - - 0.0000000002598 65.0
REGS2_k127_1115_0 general secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 310.0
REGS2_k127_1115_1 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000344 274.0
REGS2_k127_1115_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000000001749 237.0
REGS2_k127_1115_3 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000000000000000000000007054 167.0
REGS2_k127_1115_4 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000001972 141.0
REGS2_k127_1115_5 General secretion pathway K02462 - - 0.00000000000000000000000000000002453 132.0
REGS2_k127_1115_6 general secretion pathway protein K02456,K02457,K02458,K02650 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000008596 78.0
REGS2_k127_1115_7 general secretion pathway protein K02463 - - 0.00000000217 65.0
REGS2_k127_1122790_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 594.0
REGS2_k127_1122790_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 459.0
REGS2_k127_1122790_2 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000000000002182 206.0
REGS2_k127_1122790_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000008745 57.0
REGS2_k127_1142972_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1341.0
REGS2_k127_1142972_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1295.0
REGS2_k127_1142972_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0 1015.0
REGS2_k127_1142972_3 metal-dependent phosphohydrolase HD sub domain - - - 3.56e-241 754.0
REGS2_k127_1142972_4 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 419.0
REGS2_k127_1142972_5 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 423.0
REGS2_k127_1142972_6 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 412.0
REGS2_k127_1142972_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 334.0
REGS2_k127_1142972_8 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 266.0
REGS2_k127_1142972_9 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000003922 210.0
REGS2_k127_1143656_0 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 562.0
REGS2_k127_1143656_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 355.0
REGS2_k127_1143656_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000937 286.0
REGS2_k127_1143656_3 Protein of unknown function (DUF2569) - - - 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
REGS2_k127_1143656_4 Tetratricopeptide repeats - - - 0.00000000000000000000000000005823 122.0
REGS2_k127_1178544_0 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 432.0
REGS2_k127_1178544_1 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 289.0
REGS2_k127_1178544_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008805 244.0
REGS2_k127_1178544_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000003498 220.0
REGS2_k127_1178544_4 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000000003382 154.0
REGS2_k127_119419_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.925e-250 778.0
REGS2_k127_119419_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 464.0
REGS2_k127_119419_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 354.0
REGS2_k127_119419_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 347.0
REGS2_k127_119419_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000002299 231.0
REGS2_k127_119419_5 ThiS family K03154 - - 0.0000000000000000000004504 96.0
REGS2_k127_119419_7 2-nitropropane dioxygenase - - - 0.0000000000000982 72.0
REGS2_k127_1213219_0 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 501.0
REGS2_k127_1213219_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 471.0
REGS2_k127_1213219_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001024 276.0
REGS2_k127_1213219_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000001005 154.0
REGS2_k127_1213219_4 OmpA-like transmembrane domain K03286 - - 0.00000000000000000000000000000000994 133.0
REGS2_k127_1213219_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000001568 64.0
REGS2_k127_124844_0 SMART adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 515.0
REGS2_k127_124844_1 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000001622 223.0
REGS2_k127_124844_2 TIGRFAM PAS sensor protein - - - 0.000000000000000001191 100.0
REGS2_k127_1322251_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.053e-236 733.0
REGS2_k127_1322251_1 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.42e-232 726.0
REGS2_k127_1322251_2 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 406.0
REGS2_k127_1322251_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 321.0
REGS2_k127_1322251_4 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 304.0
REGS2_k127_1322251_5 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000003388 128.0
REGS2_k127_1338566_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 3.7e-322 991.0
REGS2_k127_1338566_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 5.939e-319 979.0
REGS2_k127_1341454_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 606.0
REGS2_k127_1341454_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 438.0
REGS2_k127_1359777_0 heat shock protein binding - - - 0.0 1007.0
REGS2_k127_1359777_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 1.734e-293 924.0
REGS2_k127_1359777_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000009116 124.0
REGS2_k127_1359777_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.06e-250 777.0
REGS2_k127_1359777_3 Cytochrome c7 and related cytochrome c - - - 4.059e-213 683.0
REGS2_k127_1359777_4 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 8.799e-206 647.0
REGS2_k127_1359777_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 449.0
REGS2_k127_1359777_6 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 434.0
REGS2_k127_1359777_7 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 422.0
REGS2_k127_1359777_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001353 250.0
REGS2_k127_1359777_9 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000001276 207.0
REGS2_k127_141826_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 2.483e-205 644.0
REGS2_k127_141826_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 441.0
REGS2_k127_141826_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 252.0
REGS2_k127_141826_3 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 260.0
REGS2_k127_141826_4 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000000000000000000000002968 178.0
REGS2_k127_141826_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000008736 168.0
REGS2_k127_1424091_0 AcyL-CoA dehydrogenase K06445 - - 6.135e-304 951.0
REGS2_k127_1424091_1 AMP-binding enzyme K01897 - 6.2.1.3 5.061e-251 788.0
REGS2_k127_1424091_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 445.0
REGS2_k127_1424091_3 PFAM thioesterase superfamily protein K10806 - - 0.00000000000000000000000000000000000000000000000000000000000000003018 225.0
REGS2_k127_1424091_4 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.00000000001135 64.0
REGS2_k127_1425376_0 Neisseria PilC beta-propeller domain K02674 - - 4.307e-301 989.0
REGS2_k127_1425376_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 490.0
REGS2_k127_1425376_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 407.0
REGS2_k127_1425376_3 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 254.0
REGS2_k127_1425376_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000002823 162.0
REGS2_k127_1425376_5 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000002953 135.0
REGS2_k127_1544057_0 Sigma-70 factor, region 1.2 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 417.0
REGS2_k127_1544057_1 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 329.0
REGS2_k127_1544057_2 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
REGS2_k127_1544057_3 LPP20 lipoprotein - - - 0.00000000000000000000000000000000000000000000005367 183.0
REGS2_k127_1544057_4 LPP20 lipoprotein - - - 0.000000000000000000000000000000003676 138.0
REGS2_k127_1547275_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 462.0
REGS2_k127_1547275_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 423.0
REGS2_k127_1547275_2 beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 389.0
REGS2_k127_1547275_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 321.0
REGS2_k127_1547275_4 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000004505 180.0
REGS2_k127_1547275_5 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000004282 81.0
REGS2_k127_1547275_6 - - - - 0.0000000000002549 72.0
REGS2_k127_1581674_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.023e-252 783.0
REGS2_k127_1581674_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 607.0
REGS2_k127_1581674_2 Rhomboid family - - - 0.0000000000000000000001696 103.0
REGS2_k127_1581674_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000001024 91.0
REGS2_k127_15988_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 447.0
REGS2_k127_15988_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000116 237.0
REGS2_k127_15988_2 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000001593 203.0
REGS2_k127_167949_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 488.0
REGS2_k127_167949_1 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 443.0
REGS2_k127_168563_0 Alpha-2-Macroglobulin K06894 - - 0.0 1297.0
REGS2_k127_168563_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1093.0
REGS2_k127_168563_2 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 556.0
REGS2_k127_168563_3 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 497.0
REGS2_k127_168563_4 PFAM Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 475.0
REGS2_k127_168563_5 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 350.0
REGS2_k127_168563_6 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000009715 208.0
REGS2_k127_168563_7 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0000000000000000000000000000000000000000000000000000001704 211.0
REGS2_k127_168563_8 DNA-binding protein VF530 - - - 0.000000000000000000000000000006247 119.0
REGS2_k127_168563_9 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000007065 63.0
REGS2_k127_1726396_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1398.0
REGS2_k127_1726396_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 597.0
REGS2_k127_1726396_2 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 582.0
REGS2_k127_1726396_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 511.0
REGS2_k127_1726396_4 Zinc-finger domain - - - 0.00000000000000000000000004391 111.0
REGS2_k127_1726396_5 ZIP Zinc transporter K16267 - - 0.000008339 49.0
REGS2_k127_1726396_6 - - - - 0.0006183 48.0
REGS2_k127_1732967_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 1.859e-270 837.0
REGS2_k127_1732967_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 9.235e-259 803.0
REGS2_k127_1732967_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.66e-215 671.0
REGS2_k127_1732967_3 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 594.0
REGS2_k127_1732967_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 522.0
REGS2_k127_1732967_5 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 513.0
REGS2_k127_1732967_6 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 400.0
REGS2_k127_1732967_7 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 388.0
REGS2_k127_1732967_8 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000002168 186.0
REGS2_k127_1733202_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.652e-306 945.0
REGS2_k127_1733202_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 337.0
REGS2_k127_1733202_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 315.0
REGS2_k127_1733202_3 PFAM PEGA domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 282.0
REGS2_k127_1733202_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 270.0
REGS2_k127_1733202_5 Chemoreceptor zinc-binding domain - - - 0.00000000000000000000000000000000000000000002328 166.0
REGS2_k127_1734332_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1256.0
REGS2_k127_1734332_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 297.0
REGS2_k127_1738571_0 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.903e-293 902.0
REGS2_k127_1738571_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 571.0
REGS2_k127_1738571_2 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 543.0
REGS2_k127_1738571_3 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 501.0
REGS2_k127_1738571_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 396.0
REGS2_k127_1738571_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003969 246.0
REGS2_k127_1738571_6 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000002383 133.0
REGS2_k127_1738571_7 Protein of unknown function (DUF1289) K06938 - - 0.000000000000000001547 87.0
REGS2_k127_1738571_8 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000002347 76.0
REGS2_k127_1769175_0 DAHP synthetase I family K03856 - 2.5.1.54 2.238e-217 677.0
REGS2_k127_1769175_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 337.0
REGS2_k127_1769175_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 321.0
REGS2_k127_1769175_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004514 260.0
REGS2_k127_1769175_4 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001403 240.0
REGS2_k127_1769175_5 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000003744 189.0
REGS2_k127_1769175_6 YCII-related domain K09780 - - 0.0000000000000000000000000000000000007283 143.0
REGS2_k127_1769175_7 BolA-like protein K05527 - - 0.00000000000000000000000000005019 118.0
REGS2_k127_1769295_0 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 382.0
REGS2_k127_1769295_1 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 302.0
REGS2_k127_1769295_10 - - - - 0.000000000001597 68.0
REGS2_k127_1769295_2 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000058 145.0
REGS2_k127_1769295_3 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000002815 126.0
REGS2_k127_1769295_4 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000001537 119.0
REGS2_k127_1769295_5 CsbD-like - - - 0.000000000000000000000007601 102.0
REGS2_k127_1769295_6 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000319 103.0
REGS2_k127_1769295_7 Protein of unknown function (DUF3309) - - - 0.00000000000000000001387 91.0
REGS2_k127_1769295_8 2-aminoethylphosphonate-pyruvate transaminase activity - - - 0.00000000000000000006758 93.0
REGS2_k127_1769295_9 alginic acid biosynthetic process K20276 - - 0.0000000000000001973 80.0
REGS2_k127_1799041_0 Hsp70 protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1112.0
REGS2_k127_1799041_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 591.0
REGS2_k127_1799041_2 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 567.0
REGS2_k127_1799041_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 391.0
REGS2_k127_1799041_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 324.0
REGS2_k127_1799041_5 LemA Family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 286.0
REGS2_k127_1799041_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 282.0
REGS2_k127_1799041_7 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001363 274.0
REGS2_k127_1799041_8 - - - - 0.0000000000000000000000000000000000000000000000000000004216 201.0
REGS2_k127_1809207_0 Sugar (and other) transporter - - - 3.098e-249 777.0
REGS2_k127_1809207_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 324.0
REGS2_k127_1820173_0 Major Facilitator Superfamily - - - 6.102e-205 644.0
REGS2_k127_1820173_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 536.0
REGS2_k127_1820173_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 434.0
REGS2_k127_1820173_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 349.0
REGS2_k127_1820173_4 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 324.0
REGS2_k127_1820173_5 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 316.0
REGS2_k127_1820173_6 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004636 250.0
REGS2_k127_1820173_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000159 216.0
REGS2_k127_1820173_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000005206 175.0
REGS2_k127_1820173_9 PFAM S-layer homology domain - - - 0.0001304 51.0
REGS2_k127_1827506_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 455.0
REGS2_k127_1827506_1 P-type ATPase K01531,K12955 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 329.0
REGS2_k127_1827506_2 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 291.0
REGS2_k127_1827506_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00006935 45.0
REGS2_k127_1834916_0 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 578.0
REGS2_k127_1834916_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000001286 199.0
REGS2_k127_1834916_2 ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000001438 197.0
REGS2_k127_1834916_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000002532 167.0
REGS2_k127_1847055_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 413.0
REGS2_k127_1847055_1 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 351.0
REGS2_k127_1852492_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 522.0
REGS2_k127_1852492_1 Protein of unknown function (DUF2846) - - - 0.00000000005502 68.0
REGS2_k127_1852778_0 Multicopper oxidase - - - 3.007e-239 754.0
REGS2_k127_1852778_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 602.0
REGS2_k127_1889736_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 474.0
REGS2_k127_1889736_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 410.0
REGS2_k127_1889736_2 May protect the nitrogenase Fe-Mo protein from oxidative damage K02595 - - 0.0000000000000000000000001098 112.0
REGS2_k127_1889736_3 Protein conserved in bacteria - - - 0.0000000001955 71.0
REGS2_k127_1896459_0 PFAM aminotransferase class I and II K00812 - 2.6.1.1 1.862e-241 748.0
REGS2_k127_1896459_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 387.0
REGS2_k127_1896459_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 333.0
REGS2_k127_1896459_3 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000001066 67.0
REGS2_k127_1910334_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 376.0
REGS2_k127_1910334_1 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000000007897 219.0
REGS2_k127_1910334_2 DoxX-like family - - - 0.0000000000000000000000000000000000000004509 154.0
REGS2_k127_1910334_3 - - - - 0.000000000000000000000000000000000006491 141.0
REGS2_k127_1910334_4 Family of unknown function (DUF5329) - - - 0.00000000000000000000000000000009322 130.0
REGS2_k127_1910334_5 Transcriptional regulator - - - 0.00000000000000000000000000284 116.0
REGS2_k127_1910334_7 epimerase dehydratase - - - 0.0000000003595 61.0
REGS2_k127_1910334_8 D-alanyl-D-alanine carboxypeptidase - - - 0.0000008795 59.0
REGS2_k127_1915264_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.064e-260 812.0
REGS2_k127_1915264_1 PFAM H transporting two-sector ATPase gamma subunit K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 390.0
REGS2_k127_1915264_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000005218 181.0
REGS2_k127_1923832_0 PFAM Spermine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 363.0
REGS2_k127_1923832_1 Carbohydrate-selective porin, OprB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 351.0
REGS2_k127_1923832_2 Protein of unknown function (DUF2937) - - - 0.000000000000000000000000000000000000000000000000000000000175 207.0
REGS2_k127_1939414_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 506.0
REGS2_k127_1939414_1 S4 RNA-binding domain K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 407.0
REGS2_k127_1939414_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 348.0
REGS2_k127_1946680_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.693e-305 948.0
REGS2_k127_1946680_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 2.168e-207 648.0
REGS2_k127_1946680_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 545.0
REGS2_k127_1946680_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 409.0
REGS2_k127_1946680_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 366.0
REGS2_k127_1946680_5 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 349.0
REGS2_k127_1946680_6 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003497 269.0
REGS2_k127_1946680_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 260.0
REGS2_k127_1946680_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000001258 145.0
REGS2_k127_1946680_9 membrane protein domain - - - 0.000000000000000000000000000000001806 143.0
REGS2_k127_1951845_0 Soluble lytic murein transglycosylase L domain K08309 - - 1.126e-239 758.0
REGS2_k127_1951845_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 5.732e-204 642.0
REGS2_k127_1951845_10 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000007037 212.0
REGS2_k127_1951845_11 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000001127 183.0
REGS2_k127_1951845_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.000000000000000000000000000000001949 133.0
REGS2_k127_1951845_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 607.0
REGS2_k127_1951845_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 350.0
REGS2_k127_1951845_4 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 318.0
REGS2_k127_1951845_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 292.0
REGS2_k127_1951845_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 279.0
REGS2_k127_1951845_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
REGS2_k127_1951845_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
REGS2_k127_1951845_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000000004103 235.0
REGS2_k127_1968872_0 Putative diguanylate phosphodiesterase - - - 3.76e-252 792.0
REGS2_k127_1968872_1 Histidine kinase K02482 - 2.7.13.3 9.042e-201 633.0
REGS2_k127_1968872_2 cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 499.0
REGS2_k127_1968872_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 383.0
REGS2_k127_1968872_4 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 343.0
REGS2_k127_1968872_5 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 328.0
REGS2_k127_1968872_6 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007713 256.0
REGS2_k127_1968872_8 PFAM porin Gram-negative type - - - 0.000000003588 59.0
REGS2_k127_1968872_9 Tar ligand binding domain homologue K05874 - - 0.0005064 46.0
REGS2_k127_1993915_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 405.0
REGS2_k127_1993915_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 310.0
REGS2_k127_1993915_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009992 246.0
REGS2_k127_19995_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 348.0
REGS2_k127_19995_1 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 331.0
REGS2_k127_19995_2 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
REGS2_k127_19995_3 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000003816 152.0
REGS2_k127_19995_5 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000000000000000000008062 96.0
REGS2_k127_207165_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1680.0
REGS2_k127_207165_1 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 477.0
REGS2_k127_2074708_0 Two component signalling adaptor domain - - - 2.891e-207 658.0
REGS2_k127_2074708_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 475.0
REGS2_k127_2074708_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002101 238.0
REGS2_k127_2074708_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000004491 173.0
REGS2_k127_2074708_4 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000001079 137.0
REGS2_k127_2074708_5 Sulfite exporter TauE/SafE - - - 0.0000006155 51.0
REGS2_k127_2088684_0 PFAM polysaccharide biosynthesis protein CapD - - - 1.891e-284 886.0
REGS2_k127_2088684_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
REGS2_k127_211060_0 Glycosyltransferase Family 4 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 479.0
REGS2_k127_211060_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 332.0
REGS2_k127_211060_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000004398 111.0
REGS2_k127_211060_3 glycosyl transferase family 2 K12984 - - 0.0000001036 53.0
REGS2_k127_2117869_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1632.0
REGS2_k127_2117869_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 422.0
REGS2_k127_2117869_2 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000003305 230.0
REGS2_k127_2117869_3 Tellurite resistance protein TehB - - - 0.000000000000000000000004429 102.0
REGS2_k127_2119005_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 2.802e-224 703.0
REGS2_k127_2119005_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 431.0
REGS2_k127_2119005_2 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 326.0
REGS2_k127_2119005_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
REGS2_k127_2119005_4 Protein of unknown function (DUF615) K09889 - - 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
REGS2_k127_2119005_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000003679 145.0
REGS2_k127_2132282_0 anti-sigma regulatory factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 441.0
REGS2_k127_2132282_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 375.0
REGS2_k127_2132282_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 372.0
REGS2_k127_2132282_3 - K17762 - - 0.0000000000000000000000000000000000343 136.0
REGS2_k127_2132282_4 Product type h extrachromosomal origin K07497 - - 0.000000000001275 67.0
REGS2_k127_2152594_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.415e-233 725.0
REGS2_k127_2152594_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 439.0
REGS2_k127_2152594_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 377.0
REGS2_k127_2152594_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 362.0
REGS2_k127_2152594_4 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000003524 123.0
REGS2_k127_2185168_0 PFAM CHAD domain containing protein - - - 3.639e-200 635.0
REGS2_k127_2185168_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 556.0
REGS2_k127_2185168_2 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000006206 230.0
REGS2_k127_2185168_3 MazG-like family - - - 0.000000000000000000000000000000000000003532 148.0
REGS2_k127_2185168_4 Putative quorum-sensing-regulated virulence factor K09954 - - 0.000000000000000000000000000000000156 133.0
REGS2_k127_2198685_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 497.0
REGS2_k127_2198685_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 379.0
REGS2_k127_2198685_2 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
REGS2_k127_2198685_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000007 258.0
REGS2_k127_2198685_4 Transferase hexapeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000072 243.0
REGS2_k127_2198685_5 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000004487 224.0
REGS2_k127_2198685_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000001634 189.0
REGS2_k127_2242079_0 Spermidine synthase K00797 - 2.5.1.16 2.66e-197 629.0
REGS2_k127_2242079_1 4 iron, 4 sulfur cluster binding K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 563.0
REGS2_k127_2242079_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 423.0
REGS2_k127_2242079_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
REGS2_k127_2242079_4 - - - - 0.00000000000000000000000000000000000000000000007789 171.0
REGS2_k127_2242079_5 - - - - 0.0000000000000000000000004006 112.0
REGS2_k127_2242079_6 - K06950 - - 0.000000000000000004197 86.0
REGS2_k127_2255191_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1381.0
REGS2_k127_2255191_1 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 3.714e-207 647.0
REGS2_k127_2255191_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 559.0
REGS2_k127_2255191_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 484.0
REGS2_k127_2260630_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 9.014e-205 640.0
REGS2_k127_2260630_1 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000007957 249.0
REGS2_k127_2260630_2 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000244 200.0
REGS2_k127_2260630_3 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.0000000000000000000000000000000000000000000001213 170.0
REGS2_k127_2260630_4 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000000000000000002502 164.0
REGS2_k127_2260630_5 Protein of unknown function (DUF559) K03427 - 2.1.1.72 0.00000000000000000000000000000000000000004473 155.0
REGS2_k127_2260630_6 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000001103 106.0
REGS2_k127_2455348_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.709e-272 842.0
REGS2_k127_2455348_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000546 170.0
REGS2_k127_2455348_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000005437 156.0
REGS2_k127_2465267_0 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 456.0
REGS2_k127_2465267_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006897 271.0
REGS2_k127_2465267_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000007278 55.0
REGS2_k127_2484473_0 PFAM Signal transduction response regulator, receiver K13041 - - 0.00000000000000000000000000000000000000000000000000000000002119 212.0
REGS2_k127_2484473_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004554 229.0
REGS2_k127_2484473_2 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00003872 46.0
REGS2_k127_2484473_3 TRAP transporter solute receptor TAXI family - - - 0.0001282 46.0
REGS2_k127_2491213_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.942e-245 763.0
REGS2_k127_2491213_1 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 593.0
REGS2_k127_2491213_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000003467 199.0
REGS2_k127_2491213_11 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000000000000366 153.0
REGS2_k127_2491213_12 dehydratase - - - 0.0000000000000000000000000000000000001781 149.0
REGS2_k127_2491213_13 FabA-like domain - - - 0.0000000000000000000000000001726 117.0
REGS2_k127_2491213_2 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 574.0
REGS2_k127_2491213_3 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 547.0
REGS2_k127_2491213_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 396.0
REGS2_k127_2491213_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 386.0
REGS2_k127_2491213_6 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 386.0
REGS2_k127_2491213_7 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 353.0
REGS2_k127_2491213_8 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 339.0
REGS2_k127_2491213_9 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000005266 240.0
REGS2_k127_25954_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.444e-230 714.0
REGS2_k127_25954_1 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 353.0
REGS2_k127_25954_2 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 319.0
REGS2_k127_25954_3 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000006488 228.0
REGS2_k127_25954_4 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000002805 203.0
REGS2_k127_25954_5 DsrE/DsrF-like family K07236 - - 0.00000000000000000000000000000000000000000000000000000006127 202.0
REGS2_k127_25954_6 DsrH like protein K07237 - - 0.0000000000000000000000000000000000002888 142.0
REGS2_k127_2597097_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 374.0
REGS2_k127_2597097_1 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 283.0
REGS2_k127_2597097_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000002205 263.0
REGS2_k127_2597097_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000009301 194.0
REGS2_k127_2597097_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000001733 169.0
REGS2_k127_2609371_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.804e-311 968.0
REGS2_k127_2609371_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.091e-207 655.0
REGS2_k127_2609371_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 396.0
REGS2_k127_2609371_3 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 307.0
REGS2_k127_2609371_4 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 295.0
REGS2_k127_2609371_5 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000003661 196.0
REGS2_k127_2609371_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000001086 177.0
REGS2_k127_2609371_7 Frataxin-like domain K06202 - - 0.0000000000000000000000000000000000000000008671 158.0
REGS2_k127_2621136_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2673.0
REGS2_k127_2621136_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.28e-300 924.0
REGS2_k127_2621136_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000001482 263.0
REGS2_k127_2621136_3 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000164 126.0
REGS2_k127_2632177_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 306.0
REGS2_k127_2632177_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000000000000002693 236.0
REGS2_k127_2632177_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000802 185.0
REGS2_k127_2633478_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.47e-239 758.0
REGS2_k127_2633478_1 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 473.0
REGS2_k127_2633478_2 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001633 279.0
REGS2_k127_2644009_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 1.716e-252 785.0
REGS2_k127_2644009_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.033e-242 758.0
REGS2_k127_2644009_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 409.0
REGS2_k127_2644009_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 395.0
REGS2_k127_2644009_5 - - - - 0.000000004202 59.0
REGS2_k127_2644009_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00003161 49.0
REGS2_k127_2661002_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.205e-290 902.0
REGS2_k127_2661002_1 PFAM Peptidase S24 S26A S26B, conserved region K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
REGS2_k127_2661002_10 - - - - 0.000000000009106 69.0
REGS2_k127_2661002_11 TM2 domain containing protein - - - 0.0000001356 58.0
REGS2_k127_2661002_12 - - - - 0.0000004986 51.0
REGS2_k127_2661002_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004359 265.0
REGS2_k127_2661002_3 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000153 250.0
REGS2_k127_2661002_4 - - - - 0.0000000000000000000000000000000000000000000000000009889 192.0
REGS2_k127_2661002_5 serine threonine protein kinase - - - 0.0000000000000000000000000000000000004828 143.0
REGS2_k127_2661002_6 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000002824 140.0
REGS2_k127_2661002_7 Protein tyrosine kinase - - - 0.00000000000000000000000000002074 133.0
REGS2_k127_2661002_8 - - - - 0.000000000000000000000001919 109.0
REGS2_k127_2661002_9 - - - - 0.000000000004425 74.0
REGS2_k127_268974_0 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 495.0
REGS2_k127_268974_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 420.0
REGS2_k127_268974_2 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 361.0
REGS2_k127_268974_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
REGS2_k127_268974_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000008892 177.0
REGS2_k127_268974_5 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000133 113.0
REGS2_k127_2693670_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1422.0
REGS2_k127_2693670_1 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 388.0
REGS2_k127_2693670_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 327.0
REGS2_k127_2693670_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 294.0
REGS2_k127_2693670_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 273.0
REGS2_k127_2693670_5 - - - - 0.000000000000000000000000000001327 126.0
REGS2_k127_2693670_6 ABC-type phosphate transport system, periplasmic component - - - 0.000000000000000000000000000004133 124.0
REGS2_k127_2693670_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000001486 96.0
REGS2_k127_2717738_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1099.0
REGS2_k127_2717738_1 Belongs to the glycosyl hydrolase 57 family - - - 1.028e-235 742.0
REGS2_k127_2717738_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.669e-220 688.0
REGS2_k127_2717738_3 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 491.0
REGS2_k127_2717738_4 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000000000000000000000006678 151.0
REGS2_k127_2733939_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1130.0
REGS2_k127_2733939_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.801e-282 872.0
REGS2_k127_2733939_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 9.581e-244 760.0
REGS2_k127_2733939_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 602.0
REGS2_k127_2733939_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 593.0
REGS2_k127_2733939_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 302.0
REGS2_k127_2733939_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 286.0
REGS2_k127_2733939_7 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000009417 243.0
REGS2_k127_2733939_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000003892 174.0
REGS2_k127_2817045_0 PFAM ABC transporter related - - - 0.0 997.0
REGS2_k127_2817045_1 Ammonium Transporter Family K03320 - - 4.149e-279 863.0
REGS2_k127_2817045_2 Glutamate-cysteine ligase K01919 - 6.3.2.2 2.015e-228 711.0
REGS2_k127_2817045_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 508.0
REGS2_k127_2817045_4 serine-type endopeptidase activity K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 524.0
REGS2_k127_2817045_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 387.0
REGS2_k127_2817045_6 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000002585 199.0
REGS2_k127_2817045_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000001863 163.0
REGS2_k127_2825958_0 MgtE intracellular N domain K06213 - - 1.996e-249 776.0
REGS2_k127_2825958_1 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000001404 174.0
REGS2_k127_2825958_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000001713 115.0
REGS2_k127_2825958_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000001116 53.0
REGS2_k127_284710_0 DHH family K07462 - - 2.819e-269 839.0
REGS2_k127_284710_1 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 5.775e-235 730.0
REGS2_k127_284710_2 PFAM WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000125 192.0
REGS2_k127_289433_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1433.0
REGS2_k127_289433_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 327.0
REGS2_k127_2904300_0 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 535.0
REGS2_k127_2904300_1 DSBA Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 311.0
REGS2_k127_292438_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1117.0
REGS2_k127_292438_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 567.0
REGS2_k127_292438_2 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 377.0
REGS2_k127_292438_3 Domain of unknown function (DUF4845) - - - 0.00000000000000000005136 94.0
REGS2_k127_2989551_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 462.0
REGS2_k127_2989551_1 PFAM Glycosyl transferase, family 4, conserved region K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 464.0
REGS2_k127_2989551_2 Male sterility protein K00091,K01784 - 1.1.1.219,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
REGS2_k127_2989551_3 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 361.0
REGS2_k127_3061351_0 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 586.0
REGS2_k127_3061351_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 532.0
REGS2_k127_3061351_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 524.0
REGS2_k127_3061351_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000004633 224.0
REGS2_k127_3128974_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1018.0
REGS2_k127_3128974_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 564.0
REGS2_k127_3128974_2 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 466.0
REGS2_k127_3128974_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 339.0
REGS2_k127_3128974_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000007943 233.0
REGS2_k127_3128974_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000001781 174.0
REGS2_k127_3130306_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 4.245e-253 786.0
REGS2_k127_3130306_1 Belongs to the NifD NifK NifE NifN family K02592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 611.0
REGS2_k127_3130306_2 Dinitrogenase reductase K05951 - 2.4.2.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 346.0
REGS2_k127_3130306_3 Nitrogen fixation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004505 237.0
REGS2_k127_3130306_4 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.00000000000000000000000000000000000000000000000000000000000000007585 226.0
REGS2_k127_3130306_5 Ferredoxin III, nif-specific - - - 0.0000000000000000000000000000000000000000001256 161.0
REGS2_k127_3130306_6 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.0000000000000000000000000004447 114.0
REGS2_k127_3130306_7 Rop-like - - - 0.00000000000000000009917 90.0
REGS2_k127_3265038_0 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 515.0
REGS2_k127_3265038_1 PFAM cytochrome c class I K02305 - - 0.00000000000000000000000000000000000000000000001197 173.0
REGS2_k127_3346798_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 490.0
REGS2_k127_3346798_1 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 457.0
REGS2_k127_3346798_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 456.0
REGS2_k127_3346798_3 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 391.0
REGS2_k127_3346798_4 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 377.0
REGS2_k127_3346798_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 289.0
REGS2_k127_3346798_6 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002964 263.0
REGS2_k127_3346798_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000001423 213.0
REGS2_k127_3346798_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000001614 93.0
REGS2_k127_3449795_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.502e-274 848.0
REGS2_k127_3449795_1 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 374.0
REGS2_k127_3473082_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 568.0
REGS2_k127_3473082_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
REGS2_k127_3473082_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000002537 126.0
REGS2_k127_3473082_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000002465 120.0
REGS2_k127_3473118_0 PFAM EAL domain - - - 4.758e-269 865.0
REGS2_k127_3473118_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 4.142e-255 800.0
REGS2_k127_3473118_10 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000002299 143.0
REGS2_k127_3473118_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000000003878 131.0
REGS2_k127_3473118_12 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000001636 127.0
REGS2_k127_3473118_13 COG0666 FOG Ankyrin repeat K06867 - - 0.0000000000000000000000000000003584 138.0
REGS2_k127_3473118_15 - - - - 0.00000000000000000000594 95.0
REGS2_k127_3473118_16 Tetratricopeptide repeat - - - 0.000000000000000005525 94.0
REGS2_k127_3473118_17 ATPase activity K02065 - - 0.0000000000364 72.0
REGS2_k127_3473118_18 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00005403 47.0
REGS2_k127_3473118_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007015 275.0
REGS2_k127_3473118_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000002741 243.0
REGS2_k127_3473118_4 Pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000005025 229.0
REGS2_k127_3473118_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000002688 200.0
REGS2_k127_3473118_6 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000689 180.0
REGS2_k127_3473118_7 Dihydroneopterin aldolase - - - 0.0000000000000000000000000000000000000000000004922 171.0
REGS2_k127_3473118_8 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000003351 166.0
REGS2_k127_3473118_9 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000009933 151.0
REGS2_k127_3490427_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1026.0
REGS2_k127_3490427_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 450.0
REGS2_k127_3490427_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000005001 254.0
REGS2_k127_3499214_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.855e-250 775.0
REGS2_k127_3499214_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 542.0
REGS2_k127_3499214_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 408.0
REGS2_k127_3499214_3 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 386.0
REGS2_k127_3499214_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000002047 205.0
REGS2_k127_3499214_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000001338 142.0
REGS2_k127_3508478_0 Peptidase family U32 C-terminal domain K08303 - - 1.631e-276 852.0
REGS2_k127_3508478_1 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 458.0
REGS2_k127_3508478_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000009574 207.0
REGS2_k127_3508478_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000000004488 171.0
REGS2_k127_3508478_4 endonuclease containing a URI domain K07461 - - 0.000000001835 58.0
REGS2_k127_3510414_0 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 488.0
REGS2_k127_3510414_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 413.0
REGS2_k127_3510414_2 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000008271 266.0
REGS2_k127_3510414_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000001994 137.0
REGS2_k127_3510414_4 antisigma factor binding K04749 - - 0.000000000000000000000000000007648 121.0
REGS2_k127_3510414_5 Histidine kinase-like ATPase domain - - - 0.000000000000000000002272 109.0
REGS2_k127_3510414_6 antisigma factor binding K04749 - - 0.0000000000000000003503 91.0
REGS2_k127_3514642_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 6.998e-220 687.0
REGS2_k127_3514642_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
REGS2_k127_3514642_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000106 168.0
REGS2_k127_3514642_3 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000000001051 148.0
REGS2_k127_3523920_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.566e-224 700.0
REGS2_k127_3523920_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 9.917e-208 648.0
REGS2_k127_3523920_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000009182 89.0
REGS2_k127_3523920_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3e-203 636.0
REGS2_k127_3523920_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 438.0
REGS2_k127_3523920_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 404.0
REGS2_k127_3523920_5 pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 402.0
REGS2_k127_3523920_6 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 317.0
REGS2_k127_3523920_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000002244 259.0
REGS2_k127_3523920_8 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.00000000000000000000000000000000000000000000000000004816 194.0
REGS2_k127_3523920_9 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000412 143.0
REGS2_k127_3554823_0 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 4.592e-307 953.0
REGS2_k127_3554823_1 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 506.0
REGS2_k127_3554823_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 355.0
REGS2_k127_3554823_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 331.0
REGS2_k127_3554823_4 - - - - 0.0000000000000000000000000000000000000000000005535 171.0
REGS2_k127_3554823_5 - - - - 0.000000000000000000003181 99.0
REGS2_k127_3555600_0 long-chain fatty acid transport protein - - - 0.0 1177.0
REGS2_k127_3555600_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1163.0
REGS2_k127_3555600_10 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000000000000000003403 161.0
REGS2_k127_3555600_11 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000127 153.0
REGS2_k127_3555600_12 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000000000000001753 154.0
REGS2_k127_3555600_13 TIGRFAM conserved repeat domain - - - 0.0000000000000000000000000000000001202 138.0
REGS2_k127_3555600_14 - - - - 0.00000000000000000000000000000001087 150.0
REGS2_k127_3555600_15 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000001577 126.0
REGS2_k127_3555600_16 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000001468 96.0
REGS2_k127_3555600_17 Product type h extrachromosomal origin K07497 - - 0.000000000001275 67.0
REGS2_k127_3555600_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1077.0
REGS2_k127_3555600_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.67e-247 768.0
REGS2_k127_3555600_4 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 1.244e-237 741.0
REGS2_k127_3555600_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 603.0
REGS2_k127_3555600_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 450.0
REGS2_k127_3555600_7 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 458.0
REGS2_k127_3555600_8 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.000000000000000000000000000000000000000000003049 172.0
REGS2_k127_3555600_9 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000009296 180.0
REGS2_k127_3587385_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 381.0
REGS2_k127_3587385_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 344.0
REGS2_k127_3587385_2 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007633 267.0
REGS2_k127_3603012_0 Oxidoreductase FAD-binding domain K14581 - 1.18.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 419.0
REGS2_k127_3603012_1 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 395.0
REGS2_k127_3603012_2 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 331.0
REGS2_k127_3603012_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002901 279.0
REGS2_k127_3603012_4 Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000000000000000000000000000000000000048 217.0
REGS2_k127_3603012_5 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.00000000000000000000000000000000000000000000000000000000000005918 214.0
REGS2_k127_3603012_6 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000002868 185.0
REGS2_k127_3603012_7 TIGRFAM transcriptional regulator, Rrf2 family K13771 - - 0.0000000000000000000000000000000000000000000001223 171.0
REGS2_k127_3603012_8 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000002168 112.0
REGS2_k127_360668_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.178e-314 963.0
REGS2_k127_360668_1 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 481.0
REGS2_k127_360668_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 368.0
REGS2_k127_360668_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 334.0
REGS2_k127_360668_4 OmpA-like transmembrane domain K03286 - - 0.00000000000003526 79.0
REGS2_k127_3608047_0 Glycosyl transferase family 21 K00694 - 2.4.1.12 6.846e-273 867.0
REGS2_k127_3608047_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 608.0
REGS2_k127_3608047_10 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000001214 192.0
REGS2_k127_3608047_11 Cellulose synthase operon protein C C-terminus (BCSC_C) K20543 - - 0.0000000000000000000000000000000000002341 157.0
REGS2_k127_3608047_12 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000000000000007045 135.0
REGS2_k127_3608047_2 cellulose synthase K20541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 578.0
REGS2_k127_3608047_3 Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 353.0
REGS2_k127_3608047_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 317.0
REGS2_k127_3608047_5 Transcriptional regulator K07782,K15852,K19666,K19734 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032465,GO:0032467,GO:0032991,GO:0032993,GO:0043254,GO:0043565,GO:0044087,GO:0044089,GO:0044212,GO:0045787,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051302,GO:0051726,GO:0051781,GO:0060255,GO:0065007,GO:0080090,GO:0090068,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004983 276.0
REGS2_k127_3608047_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000002125 257.0
REGS2_k127_3608047_7 Iron-sulfur cluster assembly enzyme K22068 - - 0.0000000000000000000000000000000000000000000000000000000000000000009924 229.0
REGS2_k127_3608047_8 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.00000000000000000000000000000000000000000000000001944 183.0
REGS2_k127_3608047_9 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000009755 174.0
REGS2_k127_3614222_0 CoA-binding domain protein K09181 - - 0.0 1424.0
REGS2_k127_3614222_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1256.0
REGS2_k127_3614222_2 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 532.0
REGS2_k127_3614222_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 363.0
REGS2_k127_3628220_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.784e-266 825.0
REGS2_k127_3628220_1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000000000000000000000000000000000000000001964 191.0
REGS2_k127_365123_0 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 593.0
REGS2_k127_365123_1 LysR substrate binding domain K13634,K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 557.0
REGS2_k127_365123_10 PFAM NifZ family protein K02597 - - 0.0000000000000000000000000003637 117.0
REGS2_k127_365123_11 PFAM NifT FixU family protein K02593 - - 0.000000000000000000000000003795 111.0
REGS2_k127_365123_12 - - - - 0.0000003835 57.0
REGS2_k127_365123_13 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000158 45.0
REGS2_k127_365123_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 477.0
REGS2_k127_365123_3 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 324.0
REGS2_k127_365123_4 LRV protein FeS4 cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008997 262.0
REGS2_k127_365123_5 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000002643 154.0
REGS2_k127_365123_6 Belongs to the HesB IscA family - - - 0.0000000000000000000000000000000000009164 142.0
REGS2_k127_365123_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000001779 135.0
REGS2_k127_365123_8 NifZ domain K02597 - - 0.00000000000000000000000000000000004008 136.0
REGS2_k127_365123_9 Protein of unknown function (DUF3024) - - - 0.000000000000000000000000000000113 128.0
REGS2_k127_3677049_0 AcrB/AcrD/AcrF family - - - 1.972e-283 881.0
REGS2_k127_3677049_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000001472 184.0
REGS2_k127_3684239_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 7.805e-293 907.0
REGS2_k127_3684239_1 response regulator receiver - - - 2.462e-243 790.0
REGS2_k127_3684239_2 chemotaxis, protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 460.0
REGS2_k127_3684239_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 367.0
REGS2_k127_3684239_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 318.0
REGS2_k127_3684239_5 Response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000004648 183.0
REGS2_k127_3684239_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001017 160.0
REGS2_k127_3684239_7 CheW-like domain - - - 0.0000000000000000000000000000000000002286 147.0
REGS2_k127_3684239_8 - - - - 0.00000000000000000000009556 104.0
REGS2_k127_3774760_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.576e-271 857.0
REGS2_k127_3774760_1 Histidine kinase K20975 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 284.0
REGS2_k127_3774760_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001307 250.0
REGS2_k127_3774760_3 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000004288 96.0
REGS2_k127_3784398_0 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 528.0
REGS2_k127_3784398_1 4 iron, 4 sulfur cluster binding K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 496.0
REGS2_k127_3784398_2 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 407.0
REGS2_k127_3806046_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 529.0
REGS2_k127_3806046_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004267 257.0
REGS2_k127_3806046_2 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000000001807 197.0
REGS2_k127_3806046_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000001262 105.0
REGS2_k127_3873694_0 Putative diguanylate phosphodiesterase - - - 4.616e-197 644.0
REGS2_k127_3873694_1 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 508.0
REGS2_k127_3873694_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 370.0
REGS2_k127_3873694_3 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 310.0
REGS2_k127_3873694_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000005224 119.0
REGS2_k127_3873694_5 - - - - 0.00000000003453 64.0
REGS2_k127_3946454_0 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 473.0
REGS2_k127_3946454_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 311.0
REGS2_k127_3946454_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000001958 129.0
REGS2_k127_3964108_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.597e-305 938.0
REGS2_k127_3964108_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 463.0
REGS2_k127_3964108_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000005069 225.0
REGS2_k127_3964108_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000001133 223.0
REGS2_k127_3964108_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000001948 139.0
REGS2_k127_3964108_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000005026 72.0
REGS2_k127_4173767_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1177.0
REGS2_k127_4173767_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 3.393e-277 857.0
REGS2_k127_4173767_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 591.0
REGS2_k127_4173767_3 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 313.0
REGS2_k127_4173767_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001432 271.0
REGS2_k127_4173767_5 - - - - 0.0000000000000000000000000000000000000000000000000000000003441 205.0
REGS2_k127_4173767_6 membrane - - - 0.000000000000000000000000000000000000000003914 158.0
REGS2_k127_4173767_7 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000001936 110.0
REGS2_k127_4337361_0 CHASE2 K01768 - 4.6.1.1 4.183e-307 949.0
REGS2_k127_4337361_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 4.334e-233 732.0
REGS2_k127_4337361_10 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000265 246.0
REGS2_k127_4337361_11 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.0000000000000000000000000000000000000000000000002299 184.0
REGS2_k127_4337361_12 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000195 153.0
REGS2_k127_4337361_13 Competence protein K02237 - - 0.00000000000000000000000001255 112.0
REGS2_k127_4337361_14 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000003022 81.0
REGS2_k127_4337361_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 463.0
REGS2_k127_4337361_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 459.0
REGS2_k127_4337361_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 391.0
REGS2_k127_4337361_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 363.0
REGS2_k127_4337361_6 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 307.0
REGS2_k127_4337361_7 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 305.0
REGS2_k127_4337361_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
REGS2_k127_4337361_9 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 266.0
REGS2_k127_4355302_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.899e-224 698.0
REGS2_k127_4355302_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 538.0
REGS2_k127_4355302_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 479.0
REGS2_k127_4355302_3 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000003474 222.0
REGS2_k127_4355302_4 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000001517 201.0
REGS2_k127_4355302_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000001407 132.0
REGS2_k127_4355302_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.00003745 46.0
REGS2_k127_4360129_0 Diguanylate cyclase - - - 2.868e-234 770.0
REGS2_k127_4360129_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
REGS2_k127_4360129_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002705 207.0
REGS2_k127_4360129_3 Cache 3/Cache 2 fusion domain K02480 - 2.7.13.3 0.000000000000000000000000000006384 121.0
REGS2_k127_4360129_4 Protein of unknown function (DUF2892) - - - 0.0000000000001472 72.0
REGS2_k127_4376705_0 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 9.612e-208 649.0
REGS2_k127_4376705_1 diguanylate cyclase K13069 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
REGS2_k127_4376705_2 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 293.0
REGS2_k127_4376705_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000003595 224.0
REGS2_k127_4376705_4 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000000000000000000000000000000008355 133.0
REGS2_k127_4376705_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000004259 89.0
REGS2_k127_4376705_6 Putative addiction module component - - - 0.000000012 60.0
REGS2_k127_4376705_7 SpoVT / AbrB like domain - - - 0.000001571 55.0
REGS2_k127_4383109_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 582.0
REGS2_k127_4383109_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 546.0
REGS2_k127_4383109_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 463.0
REGS2_k127_4383109_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 292.0
REGS2_k127_4383109_4 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000001429 194.0
REGS2_k127_4383109_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000001688 183.0
REGS2_k127_4383109_7 Trm112p-like protein K09791 - - 0.0000000000000002711 79.0
REGS2_k127_4414249_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1146.0
REGS2_k127_4414249_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.31e-229 716.0
REGS2_k127_4414249_10 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000231 242.0
REGS2_k127_4414249_11 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000002256 233.0
REGS2_k127_4414249_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000000001231 213.0
REGS2_k127_4414249_13 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000002196 123.0
REGS2_k127_4414249_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 512.0
REGS2_k127_4414249_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 415.0
REGS2_k127_4414249_4 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 403.0
REGS2_k127_4414249_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 382.0
REGS2_k127_4414249_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 354.0
REGS2_k127_4414249_7 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 336.0
REGS2_k127_4414249_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 304.0
REGS2_k127_4414249_9 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 287.0
REGS2_k127_4419506_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 473.0
REGS2_k127_4419506_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 470.0
REGS2_k127_4419506_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000008392 115.0
REGS2_k127_4419506_11 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.00000000000000000000000005554 108.0
REGS2_k127_4419506_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 385.0
REGS2_k127_4419506_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 358.0
REGS2_k127_4419506_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 335.0
REGS2_k127_4419506_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000003413 230.0
REGS2_k127_4419506_6 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000007739 204.0
REGS2_k127_4419506_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000008986 194.0
REGS2_k127_4419506_8 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000002276 165.0
REGS2_k127_4419506_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000005537 119.0
REGS2_k127_4424691_0 Belongs to the peptidase M16 family K07263 - - 2.289e-212 667.0
REGS2_k127_4424691_1 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 573.0
REGS2_k127_4424691_10 Copper binding periplasmic protein CusF K07810 - - 0.0000000000000006559 81.0
REGS2_k127_4424691_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 499.0
REGS2_k127_4424691_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 430.0
REGS2_k127_4424691_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 355.0
REGS2_k127_4424691_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005483 267.0
REGS2_k127_4424691_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003268 258.0
REGS2_k127_4424691_7 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000002202 209.0
REGS2_k127_4424691_8 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000001491 168.0
REGS2_k127_4424691_9 dUTPase - - - 0.00000000000000000000000000000000006085 143.0
REGS2_k127_4446718_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 - 6.1.1.3 1.575e-211 658.0
REGS2_k127_4446718_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 577.0
REGS2_k127_4446718_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
REGS2_k127_4446718_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000001977 207.0
REGS2_k127_4446718_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000008075 106.0
REGS2_k127_4476485_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.925e-282 873.0
REGS2_k127_4476485_1 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000005317 149.0
REGS2_k127_4515522_0 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 382.0
REGS2_k127_4515522_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 321.0
REGS2_k127_4515522_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000001967 136.0
REGS2_k127_4515522_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000001045 108.0
REGS2_k127_4515522_4 Ankyrin repeat - - - 0.00000000000004664 79.0
REGS2_k127_4515522_5 OmpA-like transmembrane domain - - - 0.00002434 56.0
REGS2_k127_4530517_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1022.0
REGS2_k127_4530517_1 Major Facilitator Superfamily K08227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 582.0
REGS2_k127_4530517_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000567 244.0
REGS2_k127_4558805_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0 1131.0
REGS2_k127_4558805_1 CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 590.0
REGS2_k127_4558805_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 393.0
REGS2_k127_4558805_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008286 270.0
REGS2_k127_4558805_4 - - - - 0.00000000000009333 74.0
REGS2_k127_4558805_5 4 iron, 4 sulfur cluster binding - - - 0.0000000005797 60.0
REGS2_k127_4558805_6 TM2 domain - - - 0.000000001559 64.0
REGS2_k127_4593932_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1247.0
REGS2_k127_4593932_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.354e-298 921.0
REGS2_k127_4593932_10 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000000003207 196.0
REGS2_k127_4593932_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000002836 186.0
REGS2_k127_4593932_12 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000000000000171 160.0
REGS2_k127_4593932_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000008921 154.0
REGS2_k127_4593932_14 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000000000000005436 144.0
REGS2_k127_4593932_2 Participates in both transcription termination and antitermination K02600 - - 7.806e-270 835.0
REGS2_k127_4593932_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 9.874e-219 683.0
REGS2_k127_4593932_4 Domain of unknown function (DUF3393) K08306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 489.0
REGS2_k127_4593932_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 413.0
REGS2_k127_4593932_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 336.0
REGS2_k127_4593932_7 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003966 283.0
REGS2_k127_4593932_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000000000000005592 228.0
REGS2_k127_4593932_9 Bacterial-like globin - - - 0.000000000000000000000000000000000000000000000000000000000585 204.0
REGS2_k127_4689310_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 528.0
REGS2_k127_4689310_1 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 429.0
REGS2_k127_4689310_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000002836 186.0
REGS2_k127_471893_0 PFAM glycosyl transferase family 39 - - - 1.618e-209 666.0
REGS2_k127_471893_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 554.0
REGS2_k127_471893_2 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 508.0
REGS2_k127_471893_3 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 461.0
REGS2_k127_471893_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 385.0
REGS2_k127_471893_5 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 312.0
REGS2_k127_471893_6 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 236.0
REGS2_k127_471893_7 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000001236 216.0
REGS2_k127_471893_8 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000001243 186.0
REGS2_k127_471893_9 - - - - 0.000000000000000000000000000000000000000004775 163.0
REGS2_k127_4721589_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 1.506e-243 758.0
REGS2_k127_4721589_1 AAA domain K02224 - 6.3.5.11,6.3.5.9 8.077e-227 711.0
REGS2_k127_4721589_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 6.746e-211 661.0
REGS2_k127_4721589_3 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 571.0
REGS2_k127_4721589_4 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 377.0
REGS2_k127_4721589_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000006906 203.0
REGS2_k127_4721589_6 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000007237 197.0
REGS2_k127_4721589_7 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000000000000000000000002183 165.0
REGS2_k127_4721589_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000005667 91.0
REGS2_k127_4721589_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000002557 87.0
REGS2_k127_47283_0 TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 4.564e-225 698.0
REGS2_k127_47283_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 599.0
REGS2_k127_47283_2 type II secretion system protein E K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 494.0
REGS2_k127_47283_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 313.0
REGS2_k127_47283_5 heat shock protein binding K05516 - - 0.00000000000000001779 94.0
REGS2_k127_47283_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000001079 81.0
REGS2_k127_47283_7 UPF0056 inner membrane protein K05595 - - 0.00000000004232 64.0
REGS2_k127_4779779_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 579.0
REGS2_k127_4779779_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 574.0
REGS2_k127_4779779_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001498 224.0
REGS2_k127_4779779_11 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000004052 177.0
REGS2_k127_4779779_12 (Lipo)protein K07287 - - 0.00000000001843 74.0
REGS2_k127_4779779_13 (Lipo)protein K07287 - - 0.0000007894 59.0
REGS2_k127_4779779_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 529.0
REGS2_k127_4779779_3 fad dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 502.0
REGS2_k127_4779779_4 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 493.0
REGS2_k127_4779779_5 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 419.0
REGS2_k127_4779779_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 376.0
REGS2_k127_4779779_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 297.0
REGS2_k127_4779779_8 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001574 251.0
REGS2_k127_4779779_9 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000393 245.0
REGS2_k127_4788990_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.185e-256 792.0
REGS2_k127_4788990_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.029e-244 758.0
REGS2_k127_4788990_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006327 222.0
REGS2_k127_4788990_11 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000247 132.0
REGS2_k127_4788990_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 531.0
REGS2_k127_4788990_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 530.0
REGS2_k127_4788990_4 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 481.0
REGS2_k127_4788990_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 393.0
REGS2_k127_4788990_6 Belongs to the ABC transporter superfamily K10111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 343.0
REGS2_k127_4788990_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 321.0
REGS2_k127_4788990_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 317.0
REGS2_k127_4788990_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002828 269.0
REGS2_k127_483049_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.39e-273 846.0
REGS2_k127_483049_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004089 264.0
REGS2_k127_483049_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 246.0
REGS2_k127_483049_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000005076 208.0
REGS2_k127_483049_4 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000001404 189.0
REGS2_k127_483049_5 Membrane fusogenic activity K09806 - - 0.0000000000000000000000001923 107.0
REGS2_k127_483049_6 Ammonium Transporter Family K03320 - - 0.00000001642 58.0
REGS2_k127_4882889_0 Domain of unknown function (DUF1926) K22451 - 2.4.1.25 1.079e-260 816.0
REGS2_k127_4882889_1 PFAM ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000008086 265.0
REGS2_k127_5011637_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 518.0
REGS2_k127_5011637_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 353.0
REGS2_k127_5011637_2 Hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 319.0
REGS2_k127_5011637_3 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.00000000001654 64.0
REGS2_k127_5048190_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.025e-261 807.0
REGS2_k127_5048190_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.766e-198 625.0
REGS2_k127_5048190_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 331.0
REGS2_k127_5048190_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003121 236.0
REGS2_k127_5048190_4 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000003163 214.0
REGS2_k127_5048190_5 DJ-1/PfpI family K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000001768 210.0
REGS2_k127_5048190_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000001214 181.0
REGS2_k127_5048190_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000000007026 160.0
REGS2_k127_5134693_0 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 468.0
REGS2_k127_5134693_1 defense response to virus K09952 - - 0.000000000000000000000000000000000000000000000000007756 208.0
REGS2_k127_5134693_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000009483 166.0
REGS2_k127_5134693_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.00000000000000002522 85.0
REGS2_k127_5134693_4 Helix-turn-helix domain - - - 0.0000001547 60.0
REGS2_k127_5154752_0 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 430.0
REGS2_k127_5154752_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 328.0
REGS2_k127_5154752_2 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002416 241.0
REGS2_k127_5179457_0 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1019.0
REGS2_k127_5179457_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.423e-240 750.0
REGS2_k127_5179457_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 522.0
REGS2_k127_5179457_3 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 501.0
REGS2_k127_5179457_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 287.0
REGS2_k127_5179457_5 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000167 267.0
REGS2_k127_5179457_6 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
REGS2_k127_5179457_7 Protein of unknown function (DUF3106) - - - 0.00000000000000000000002916 104.0
REGS2_k127_5179457_8 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000006706 66.0
REGS2_k127_5182482_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1501.0
REGS2_k127_5182482_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 581.0
REGS2_k127_5182482_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 518.0
REGS2_k127_5182482_3 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 309.0
REGS2_k127_5182482_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 292.0
REGS2_k127_5182482_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 243.0
REGS2_k127_5182482_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000005793 230.0
REGS2_k127_5182482_7 - - - - 0.00000000000006155 73.0
REGS2_k127_5182482_8 Protein conserved in bacteria - - - 0.0000000000001647 76.0
REGS2_k127_5218689_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
REGS2_k127_5218689_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009121 241.0
REGS2_k127_5218689_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000002763 192.0
REGS2_k127_5264568_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0 1005.0
REGS2_k127_5264568_1 ABC transporter K06020 - 3.6.3.25 1.425e-216 675.0
REGS2_k127_5264568_2 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 434.0
REGS2_k127_5264568_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 400.0
REGS2_k127_5264568_4 - - - - 0.00000000000000000000000000000000000000000000000000132 188.0
REGS2_k127_5264568_5 Cupin domain - - - 0.0000000000000000000000000000000000000000001391 173.0
REGS2_k127_5265784_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 604.0
REGS2_k127_5265784_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 560.0
REGS2_k127_5265784_10 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000000004228 193.0
REGS2_k127_5265784_11 OmpA family K03640 - - 0.000000000000000000000000000000000000000000000001627 179.0
REGS2_k127_5265784_12 TolA C-terminal K03646 - - 0.0000000000000000000000000000000000000000000007814 177.0
REGS2_k127_5265784_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 402.0
REGS2_k127_5265784_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 375.0
REGS2_k127_5265784_4 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 362.0
REGS2_k127_5265784_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 353.0
REGS2_k127_5265784_6 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 350.0
REGS2_k127_5265784_7 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 354.0
REGS2_k127_5265784_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000003537 216.0
REGS2_k127_5265784_9 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000862 197.0
REGS2_k127_5289284_0 serine threonine protein kinase K12132 - 2.7.11.1 1.622e-194 614.0
REGS2_k127_5289284_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 575.0
REGS2_k127_5289284_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 546.0
REGS2_k127_5289284_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 496.0
REGS2_k127_5289284_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000001244 143.0
REGS2_k127_5289284_5 Protein of unknown function (DUF1622) - - - 0.00000003026 59.0
REGS2_k127_5294186_0 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0 1190.0
REGS2_k127_5294186_1 - - - - 1.7e-322 998.0
REGS2_k127_5294186_2 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 591.0
REGS2_k127_5294186_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 511.0
REGS2_k127_5294186_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 398.0
REGS2_k127_5294186_5 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 359.0
REGS2_k127_5294186_6 PFAM AMMECR1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005362 238.0
REGS2_k127_5294186_7 Protein of unknown function (DUF3240) - - - 0.000000000000000000000000000000000000000000011 164.0
REGS2_k127_5294186_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.00000000000000008761 80.0
REGS2_k127_5298201_0 Domain of unknown function (DUF3400) - - - 0.0 2200.0
REGS2_k127_5298201_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 470.0
REGS2_k127_5298201_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000001089 106.0
REGS2_k127_5298201_2 P-loop ATPase protein family K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 433.0
REGS2_k127_5298201_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 426.0
REGS2_k127_5298201_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 374.0
REGS2_k127_5298201_5 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002286 281.0
REGS2_k127_5298201_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005464 241.0
REGS2_k127_5298201_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000000316 239.0
REGS2_k127_5298201_8 NusG domain II - - - 0.00000000000000000000000000000000000000000000000000001773 190.0
REGS2_k127_5298201_9 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000002917 168.0
REGS2_k127_5307536_0 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 533.0
REGS2_k127_5307536_1 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 290.0
REGS2_k127_5332319_0 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 372.0
REGS2_k127_5332319_1 synthase K08097 - 4.4.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002451 283.0
REGS2_k127_5332319_2 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000001459 211.0
REGS2_k127_5332319_3 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000008261 197.0
REGS2_k127_5332319_4 Histidine kinase - - - 0.0000000976 57.0
REGS2_k127_5332981_0 ABC transporter C-terminal domain K15738 - - 0.0 1073.0
REGS2_k127_5332981_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 617.0
REGS2_k127_5332981_2 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 370.0
REGS2_k127_5332981_3 Carbohydrate phosphorylase - - - 0.000000000000000003267 84.0
REGS2_k127_5346569_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1352.0
REGS2_k127_5346569_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 395.0
REGS2_k127_5349778_0 chlorophyll binding K02690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 483.0
REGS2_k127_5349778_1 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 363.0
REGS2_k127_5349778_2 Domain of unknown function (DUF386) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008585 259.0
REGS2_k127_5353157_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1930.0
REGS2_k127_5359207_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.629e-238 741.0
REGS2_k127_5359207_1 Insulinase (Peptidase family M16) K07263 - - 7.775e-196 622.0
REGS2_k127_5359207_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 288.0
REGS2_k127_5359207_11 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001144 255.0
REGS2_k127_5359207_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003269 241.0
REGS2_k127_5359207_13 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005607 238.0
REGS2_k127_5359207_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000002222 230.0
REGS2_k127_5359207_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
REGS2_k127_5359207_16 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000001284 229.0
REGS2_k127_5359207_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000001118 211.0
REGS2_k127_5359207_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000001175 192.0
REGS2_k127_5359207_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000004465 188.0
REGS2_k127_5359207_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 547.0
REGS2_k127_5359207_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000000002194 186.0
REGS2_k127_5359207_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000006776 181.0
REGS2_k127_5359207_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000000001512 180.0
REGS2_k127_5359207_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000000000001523 169.0
REGS2_k127_5359207_24 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000001257 148.0
REGS2_k127_5359207_25 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000222 141.0
REGS2_k127_5359207_26 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000004944 121.0
REGS2_k127_5359207_27 Ribosomal protein L30p/L7e K02907 - - 0.000000000000000000000000001351 112.0
REGS2_k127_5359207_28 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000002121 80.0
REGS2_k127_5359207_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000006426 74.0
REGS2_k127_5359207_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 512.0
REGS2_k127_5359207_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 428.0
REGS2_k127_5359207_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 370.0
REGS2_k127_5359207_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 364.0
REGS2_k127_5359207_7 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 359.0
REGS2_k127_5359207_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 340.0
REGS2_k127_5359207_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 306.0
REGS2_k127_539366_0 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 409.0
REGS2_k127_539366_1 COG1994 Zn-dependent proteases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 391.0
REGS2_k127_539366_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 382.0
REGS2_k127_539366_3 membrane-anchored protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 365.0
REGS2_k127_539366_4 - - - - 0.000000000000000004985 88.0
REGS2_k127_5431911_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 3.343e-237 739.0
REGS2_k127_5431911_1 4 iron, 4 sulfur cluster binding K02574 - - 0.00000000000000000000004299 102.0
REGS2_k127_5456996_0 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 499.0
REGS2_k127_5456996_1 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 380.0
REGS2_k127_5456996_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
REGS2_k127_5456996_3 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
REGS2_k127_5456996_4 - - - - 0.000000000000000000000000000000002539 134.0
REGS2_k127_5456996_5 NHL repeat - - - 0.0000000000000000003021 89.0
REGS2_k127_5456996_6 - - - - 0.00000000002129 70.0
REGS2_k127_5480162_0 PFAM cytochrome c oxidase subunit I K00404 - 1.9.3.1 3.543e-289 890.0
REGS2_k127_5480162_1 PFAM major facilitator superfamily MFS_1 - - - 4.224e-209 656.0
REGS2_k127_5480162_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000001188 207.0
REGS2_k127_5480162_11 - - - - 0.00000000000000000000000000000000000000000000000000000003496 201.0
REGS2_k127_5480162_12 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000002234 189.0
REGS2_k127_5480162_13 - - - - 0.00000000000000000000000000000000000000000001471 169.0
REGS2_k127_5480162_14 Ribosomal protein L31 K02909 - - 0.0000000000000000000000000000000000003711 143.0
REGS2_k127_5480162_16 - - - - 0.00000000000000000000000159 106.0
REGS2_k127_5480162_17 - - - - 0.00000000000001849 77.0
REGS2_k127_5480162_18 Sulfatase-modifying factor enzyme 1 K20333 - - 0.000000000002419 68.0
REGS2_k127_5480162_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 528.0
REGS2_k127_5480162_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 491.0
REGS2_k127_5480162_4 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 450.0
REGS2_k127_5480162_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 258.0
REGS2_k127_5480162_7 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000009898 246.0
REGS2_k127_5480162_8 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001363 246.0
REGS2_k127_5480162_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000004467 217.0
REGS2_k127_5503986_0 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 322.0
REGS2_k127_5503986_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 313.0
REGS2_k127_5503986_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000005194 176.0
REGS2_k127_5633595_0 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006546 278.0
REGS2_k127_5633595_1 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000001087 224.0
REGS2_k127_5633595_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000006099 191.0
REGS2_k127_5647598_0 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 352.0
REGS2_k127_5647598_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07661 - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
REGS2_k127_5647598_2 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
REGS2_k127_5647598_3 - - - - 0.000000000000000000002817 98.0
REGS2_k127_5647598_4 LysM domain - - - 0.00000000000000002105 89.0
REGS2_k127_5647598_5 - - - - 0.0000000000000001576 85.0
REGS2_k127_5665013_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.681e-226 707.0
REGS2_k127_5665013_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 3.719e-205 644.0
REGS2_k127_5665013_10 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000003989 224.0
REGS2_k127_5665013_11 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000007299 208.0
REGS2_k127_5665013_12 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000003633 184.0
REGS2_k127_5665013_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000000353 155.0
REGS2_k127_5665013_14 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000000003867 111.0
REGS2_k127_5665013_15 TIGRFAM clan AA aspartic protease, TIGR02281 family K06985 - - 0.000000003743 64.0
REGS2_k127_5665013_2 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 582.0
REGS2_k127_5665013_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 376.0
REGS2_k127_5665013_4 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 367.0
REGS2_k127_5665013_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
REGS2_k127_5665013_6 Bacterial dnaA protein K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 316.0
REGS2_k127_5665013_7 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 306.0
REGS2_k127_5665013_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
REGS2_k127_5665013_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003905 229.0
REGS2_k127_5668279_0 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008674 254.0
REGS2_k127_5668279_1 IgGFc binding protein K08455 - - 0.000000000000000000000000000000000003484 156.0
REGS2_k127_5668279_2 FecR protein - - - 0.000000000000000000000000000002857 130.0
REGS2_k127_5668279_3 Cytokinin dehydrogenase 1, FAD and cytokinin binding - - - 0.0000000000000000000005898 104.0
REGS2_k127_5668279_4 PFAM GGDEF domain containing protein - - - 0.0000000000003608 69.0
REGS2_k127_5705322_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 393.0
REGS2_k127_5705322_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000005125 180.0
REGS2_k127_5705322_2 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000004175 127.0
REGS2_k127_5706575_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0 1073.0
REGS2_k127_5706575_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1021.0
REGS2_k127_5706575_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.774e-280 866.0
REGS2_k127_5706575_3 PFAM WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 334.0
REGS2_k127_5706575_4 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000006821 187.0
REGS2_k127_5706575_6 Ryanodine receptor Ryr - - - 0.000000008375 62.0
REGS2_k127_5731805_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 6.125e-312 966.0
REGS2_k127_5731805_1 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
REGS2_k127_5731805_2 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 359.0
REGS2_k127_5731805_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003233 250.0
REGS2_k127_5731805_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000755 232.0
REGS2_k127_5731805_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000006532 188.0
REGS2_k127_5731805_6 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000004106 161.0
REGS2_k127_5748339_0 Phospholipase A1 - - - 0.000000000000000000000000000000000000000000008771 175.0
REGS2_k127_5748339_1 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000009125 145.0
REGS2_k127_5748339_2 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000002258 110.0
REGS2_k127_580254_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 570.0
REGS2_k127_580254_1 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 391.0
REGS2_k127_580254_2 Smr domain - - - 0.00000000000000000000000000000000000000000000000000000000000004327 218.0
REGS2_k127_580254_3 PFAM Signal transduction response regulator, receiver K13041 - - 0.0000000000000000000000000000000000000000000000000000000265 203.0
REGS2_k127_580254_4 NlpC/P60 family K19303 - - 0.0000000000000000000000000000000000000000000006162 170.0
REGS2_k127_580254_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000002847 147.0
REGS2_k127_580254_6 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000003085 129.0
REGS2_k127_583804_0 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 348.0
REGS2_k127_583804_1 - - - - 0.000000000000000000000000000000000000000000000000001198 189.0
REGS2_k127_5925076_0 MscS Mechanosensitive ion channel - - - 3.675e-229 717.0
REGS2_k127_5925076_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 552.0
REGS2_k127_5925076_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000001535 173.0
REGS2_k127_6027369_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 6.517e-213 665.0
REGS2_k127_6027369_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 586.0
REGS2_k127_6027369_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 562.0
REGS2_k127_6027369_3 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 447.0
REGS2_k127_6027369_4 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 443.0
REGS2_k127_6027369_5 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 396.0
REGS2_k127_6027369_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 332.0
REGS2_k127_6027369_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000009024 142.0
REGS2_k127_6027369_8 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000000004273 87.0
REGS2_k127_6027369_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000003912 66.0
REGS2_k127_6036722_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 7.47e-297 917.0
REGS2_k127_6036722_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 4.556e-237 745.0
REGS2_k127_6036722_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000002546 138.0
REGS2_k127_6036722_11 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000248 127.0
REGS2_k127_6036722_12 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000005751 115.0
REGS2_k127_6036722_2 Virulence factor membrane-bound polymerase, C-terminal - - - 1.589e-203 650.0
REGS2_k127_6036722_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 584.0
REGS2_k127_6036722_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 516.0
REGS2_k127_6036722_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 480.0
REGS2_k127_6036722_6 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 310.0
REGS2_k127_6036722_7 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000496 274.0
REGS2_k127_6036722_8 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000001161 204.0
REGS2_k127_6036722_9 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000002878 177.0
REGS2_k127_6056839_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.311e-274 861.0
REGS2_k127_6056839_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 576.0
REGS2_k127_6056839_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 531.0
REGS2_k127_6056839_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 437.0
REGS2_k127_6056839_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 345.0
REGS2_k127_6056839_5 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000004862 202.0
REGS2_k127_6056839_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000006789 51.0
REGS2_k127_6069277_0 AsmA family K07289 - - 7.56e-286 896.0
REGS2_k127_6069277_1 endonuclease III K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 548.0
REGS2_k127_6069277_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 514.0
REGS2_k127_6069277_3 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000000000000000000000000000037 139.0
REGS2_k127_6072695_0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 504.0
REGS2_k127_6072695_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 353.0
REGS2_k127_6072695_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000001144 255.0
REGS2_k127_6072695_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000004522 135.0
REGS2_k127_6082919_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.671e-315 987.0
REGS2_k127_6082919_1 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 3.403e-305 954.0
REGS2_k127_6082919_10 NADP transhydrogenase K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000000000000000003064 179.0
REGS2_k127_6082919_11 TM2 domain - - - 0.00000000000000000000000000000000003547 137.0
REGS2_k127_6082919_14 MscS Mechanosensitive ion channel - - - 0.0000000001664 63.0
REGS2_k127_6082919_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.737e-255 791.0
REGS2_k127_6082919_3 metal-dependent phosphohydrolase HD sub domain K07814 - - 1.248e-224 706.0
REGS2_k127_6082919_4 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 1.69e-198 625.0
REGS2_k127_6082919_5 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 1.972e-195 614.0
REGS2_k127_6082919_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 339.0
REGS2_k127_6082919_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 293.0
REGS2_k127_6082919_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001038 250.0
REGS2_k127_6082919_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000000006996 210.0
REGS2_k127_6085416_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.088e-226 715.0
REGS2_k127_6085416_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 7.138e-213 665.0
REGS2_k127_6085416_2 RmuC family K09760 - - 4.299e-206 647.0
REGS2_k127_6085416_3 PFAM type II secretion system K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 426.0
REGS2_k127_6085416_4 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
REGS2_k127_6085416_5 - - - - 0.0000000000000000000001609 104.0
REGS2_k127_6085416_6 Pilus assembly protein, PilO - - - 0.000000000000000002678 91.0
REGS2_k127_6085416_7 - - - - 0.000000000000000009449 94.0
REGS2_k127_6085416_8 Outer membrane protein beta-barrel domain K16079 - - 0.000000001615 66.0
REGS2_k127_6106676_0 Mur ligase family, catalytic domain K01924 - 6.3.2.8 6.222e-241 751.0
REGS2_k127_6106676_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.689e-203 637.0
REGS2_k127_6106676_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 5.138e-203 642.0
REGS2_k127_6106676_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 577.0
REGS2_k127_6106676_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 466.0
REGS2_k127_6106676_5 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000007931 248.0
REGS2_k127_6139226_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.466e-270 844.0
REGS2_k127_6139226_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.472e-221 695.0
REGS2_k127_6139226_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 587.0
REGS2_k127_6139226_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 470.0
REGS2_k127_6139226_4 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 279.0
REGS2_k127_6139226_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000001083 213.0
REGS2_k127_6139226_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000000000001137 123.0
REGS2_k127_6180135_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 467.0
REGS2_k127_6180135_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 461.0
REGS2_k127_6180135_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000003447 235.0
REGS2_k127_6180135_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000002791 222.0
REGS2_k127_6180135_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000001281 217.0
REGS2_k127_6180135_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000001385 145.0
REGS2_k127_6180135_6 polysaccharide deacetylase K01452 - 3.5.1.41 0.0000000000003344 72.0
REGS2_k127_6180412_0 Periplasmic sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 602.0
REGS2_k127_6180412_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 486.0
REGS2_k127_6180412_2 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000003634 124.0
REGS2_k127_6180412_3 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000001433 61.0
REGS2_k127_6258721_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 323.0
REGS2_k127_6258721_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000001095 232.0
REGS2_k127_6258721_2 PFAM dUTPase - - - 0.00000005642 63.0
REGS2_k127_6262456_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.19e-228 709.0
REGS2_k127_6262456_1 OmpA-like transmembrane domain K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 438.0
REGS2_k127_6262456_2 alginic acid biosynthetic process K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002094 286.0
REGS2_k127_6262456_3 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 258.0
REGS2_k127_6262456_4 Bacterial Ig-like domain (group 2) - - - 0.000000000000000000000000000000000000000000000000000000000211 214.0
REGS2_k127_6262456_6 SMART Transport-associated and nodulation - - - 0.0000000000000000000000000000006081 129.0
REGS2_k127_6262456_7 Pfam:DUF1049 - - - 0.000000001291 61.0
REGS2_k127_62811_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 416.0
REGS2_k127_62811_1 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008624 245.0
REGS2_k127_62811_2 TIGRFAM ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000000000008188 201.0
REGS2_k127_62811_3 PFAM HPP family protein K07168 - - 0.000000000000000000000000000000000000000000000000005138 188.0
REGS2_k127_62811_4 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.0000000000000000000000000000000000000002034 164.0
REGS2_k127_62811_5 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000008613 115.0
REGS2_k127_6286137_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
REGS2_k127_6286137_1 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 263.0
REGS2_k127_6286137_2 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000005849 178.0
REGS2_k127_6286137_3 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000001872 93.0
REGS2_k127_6317741_0 Outer membrane lipoprotein-sorting protein K07003 - - 5.601e-219 702.0
REGS2_k127_6317741_1 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 489.0
REGS2_k127_6317741_2 Cellulose biosynthesis protein BcsG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 482.0
REGS2_k127_6317741_3 cellulose synthase operon C domain protein K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 329.0
REGS2_k127_6317741_4 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002771 241.0
REGS2_k127_6317741_5 transcriptional regulator - - - 0.00000000000000001742 90.0
REGS2_k127_6364892_0 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 428.0
REGS2_k127_6364892_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000009241 231.0
REGS2_k127_6364892_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000001367 224.0
REGS2_k127_6364892_3 - - - - 0.000683 49.0
REGS2_k127_6370311_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 4.685e-262 821.0
REGS2_k127_6370311_1 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 524.0
REGS2_k127_6370311_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 427.0
REGS2_k127_6370311_3 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 401.0
REGS2_k127_6370311_4 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000007755 166.0
REGS2_k127_6425002_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 396.0
REGS2_k127_6425002_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 292.0
REGS2_k127_6425002_2 Protein of unknown function (DUF560) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 308.0
REGS2_k127_6425002_3 PFAM FecR protein K03832 - - 0.000000000000000000000000000000009105 138.0
REGS2_k127_6425002_4 - - - - 0.000000000000000000000000001502 114.0
REGS2_k127_6425002_5 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.000000000000000000353 88.0
REGS2_k127_6434034_0 AAA domain K16898 - 3.6.4.12 3.345e-225 711.0
REGS2_k127_6434034_1 - - - - 0.00000000000000000000000001943 115.0
REGS2_k127_6434034_2 - - - - 0.0000000000001056 70.0
REGS2_k127_6434034_3 Transposase K07486 - - 0.0000000002601 61.0
REGS2_k127_6523047_0 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 382.0
REGS2_k127_6523047_1 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 332.0
REGS2_k127_6524425_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 462.0
REGS2_k127_6524425_1 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000002515 170.0
REGS2_k127_6524425_2 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000009533 63.0
REGS2_k127_6566714_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.778e-319 983.0
REGS2_k127_6566714_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.926e-282 870.0
REGS2_k127_6566714_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.419e-241 751.0
REGS2_k127_6566714_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 449.0
REGS2_k127_6566714_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
REGS2_k127_6600920_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 589.0
REGS2_k127_6600920_1 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
REGS2_k127_6600920_2 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000001416 225.0
REGS2_k127_6600920_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000001423 124.0
REGS2_k127_6600920_4 Ribonuclease P K03536 - 3.1.26.5 0.0000000000000000001967 92.0
REGS2_k127_6600920_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002048 79.0
REGS2_k127_6646635_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1117.0
REGS2_k127_6646635_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000001517 201.0
REGS2_k127_6646635_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000113 180.0
REGS2_k127_6646635_3 - - - - 0.0000000000000000000000000000000000000001105 155.0
REGS2_k127_6647314_0 ABC1 family K03688 - - 5.563e-247 774.0
REGS2_k127_6647314_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 512.0
REGS2_k127_6647314_2 fad dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 503.0
REGS2_k127_6740163_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 604.0
REGS2_k127_6740163_1 Dienelactone hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 366.0
REGS2_k127_6740163_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 351.0
REGS2_k127_6740163_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 349.0
REGS2_k127_6740163_4 LemA Family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 319.0
REGS2_k127_6740163_5 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 295.0
REGS2_k127_6740163_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003247 277.0
REGS2_k127_6740163_7 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000002138 238.0
REGS2_k127_6790829_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 4.25e-322 988.0
REGS2_k127_6790829_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 7.995e-226 703.0
REGS2_k127_6790829_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 457.0
REGS2_k127_6793473_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 503.0
REGS2_k127_6793473_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 355.0
REGS2_k127_6793473_2 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003759 244.0
REGS2_k127_6793473_3 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000001349 119.0
REGS2_k127_6793473_4 - - - - 0.00000000000000001564 85.0
REGS2_k127_6793473_5 peptidase M48, Ste24p - - - 0.0000000000000009478 77.0
REGS2_k127_6902210_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1136.0
REGS2_k127_6902210_1 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.962e-204 642.0
REGS2_k127_6902210_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 512.0
REGS2_k127_6902210_3 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 466.0
REGS2_k127_6902210_4 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 403.0
REGS2_k127_6902210_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 253.0
REGS2_k127_6902210_6 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000000008603 128.0
REGS2_k127_6902210_7 - - - - 0.00000000000000000000000001242 111.0
REGS2_k127_6981792_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 578.0
REGS2_k127_6981792_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 342.0
REGS2_k127_6981792_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006624 274.0
REGS2_k127_6981792_3 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002753 267.0
REGS2_k127_6981792_4 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000005124 162.0
REGS2_k127_6981792_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000001701 117.0
REGS2_k127_6986265_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.796e-283 876.0
REGS2_k127_6986265_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 7.205e-244 762.0
REGS2_k127_6986265_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000002934 174.0
REGS2_k127_6986265_11 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000000000000005336 109.0
REGS2_k127_6986265_12 - K19168 - - 0.0000000000000000000000006492 109.0
REGS2_k127_6986265_2 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 521.0
REGS2_k127_6986265_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 422.0
REGS2_k127_6986265_4 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 378.0
REGS2_k127_6986265_5 TIGRFAM RNA polymerase sigma factor RpoE K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 351.0
REGS2_k127_6986265_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 339.0
REGS2_k127_6986265_7 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
REGS2_k127_6986265_8 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000000000000000000000000000000000000000000000002771 212.0
REGS2_k127_6986265_9 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000001443 201.0
REGS2_k127_6987222_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 4.458e-255 796.0
REGS2_k127_6987222_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001181 256.0
REGS2_k127_6987222_2 Plasmid stabilization system - - - 0.0000000000000000000000000406 109.0
REGS2_k127_6987222_3 Ribbon-helix-helix protein, copG family - - - 0.0000000000000002991 83.0
REGS2_k127_6991298_0 Histidine Phosphotransfer domain K02487,K06596 - - 0.0 1733.0
REGS2_k127_6991298_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1065.0
REGS2_k127_6991298_10 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 583.0
REGS2_k127_6991298_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 390.0
REGS2_k127_6991298_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 347.0
REGS2_k127_6991298_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 344.0
REGS2_k127_6991298_14 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 310.0
REGS2_k127_6991298_15 DSBA-like thioredoxin domain K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 262.0
REGS2_k127_6991298_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000002344 225.0
REGS2_k127_6991298_17 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
REGS2_k127_6991298_18 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000000000000005132 213.0
REGS2_k127_6991298_19 Two component signalling adaptor domain K02659 - - 0.000000000000000000000000000000000000000000000000000000002183 203.0
REGS2_k127_6991298_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0 1005.0
REGS2_k127_6991298_20 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000000000007657 201.0
REGS2_k127_6991298_21 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000000000000009445 184.0
REGS2_k127_6991298_22 Pfam Glutaredoxin - - - 0.000000000000000000000000000000000000001837 151.0
REGS2_k127_6991298_23 Sporulation related domain - - - 0.00000000000000000000000000000000007458 143.0
REGS2_k127_6991298_24 OmpA-like transmembrane domain K03286 - - 0.0000000000000000000000000000001274 130.0
REGS2_k127_6991298_25 - - - - 0.00000000000000000000001463 112.0
REGS2_k127_6991298_26 Product type h extrachromosomal origin K07497 - - 0.000000002254 57.0
REGS2_k127_6991298_3 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 7.293e-290 896.0
REGS2_k127_6991298_4 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.132e-257 802.0
REGS2_k127_6991298_5 Polyphosphate kinase 2 (PPK2) - - - 4.907e-249 775.0
REGS2_k127_6991298_6 Amidohydrolase family K01465 - 3.5.2.3 2.052e-248 771.0
REGS2_k127_6991298_7 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 4.254e-246 769.0
REGS2_k127_6991298_8 PFAM TrkA-N domain protein K03499 - - 9.48e-238 742.0
REGS2_k127_6991298_9 histidine kinase HAMP region domain protein K02660,K03406 - - 3.398e-203 654.0
REGS2_k127_7006424_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 488.0
REGS2_k127_7006424_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 411.0
REGS2_k127_7006424_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
REGS2_k127_7006424_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000008405 246.0
REGS2_k127_7006424_4 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000001119 215.0
REGS2_k127_7029519_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 8.892e-277 861.0
REGS2_k127_7029519_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 514.0
REGS2_k127_7033291_0 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1086.0
REGS2_k127_7033291_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 420.0
REGS2_k127_7033291_2 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001141 272.0
REGS2_k127_7033291_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000001993 238.0
REGS2_k127_7033291_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000002433 217.0
REGS2_k127_7033291_5 Cytochrome C biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000002163 207.0
REGS2_k127_7033291_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0000000000000266 73.0
REGS2_k127_7053216_0 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 461.0
REGS2_k127_7053216_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 372.0
REGS2_k127_7053216_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 296.0
REGS2_k127_7053216_3 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
REGS2_k127_7053216_4 major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
REGS2_k127_7053216_5 Transcription regulator that can specifically activate or repress expression of target genes K06075 - - 0.0000000000000000000000000000000000000000000000001291 180.0
REGS2_k127_7053216_6 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000000000000919 185.0
REGS2_k127_7065901_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 8.822e-305 940.0
REGS2_k127_7065901_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 610.0
REGS2_k127_7065901_10 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000829 256.0
REGS2_k127_7065901_11 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
REGS2_k127_7065901_12 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001691 215.0
REGS2_k127_7065901_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000155 227.0
REGS2_k127_7065901_14 - - - - 0.000000000000000000000000000000000000000000000000000000003679 206.0
REGS2_k127_7065901_15 - - - - 0.0000000000000000000000001033 113.0
REGS2_k127_7065901_16 response to antibiotic K07122 - - 0.000000000000000000004157 95.0
REGS2_k127_7065901_2 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 592.0
REGS2_k127_7065901_3 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 537.0
REGS2_k127_7065901_4 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 503.0
REGS2_k127_7065901_5 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 481.0
REGS2_k127_7065901_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 488.0
REGS2_k127_7065901_7 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 440.0
REGS2_k127_7065901_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 425.0
REGS2_k127_7065901_9 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001255 269.0
REGS2_k127_7076188_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 562.0
REGS2_k127_7076188_1 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 492.0
REGS2_k127_7076188_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 469.0
REGS2_k127_7076188_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 430.0
REGS2_k127_7076188_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 398.0
REGS2_k127_7076188_5 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002577 263.0
REGS2_k127_7076188_6 PFAM UspA domain protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
REGS2_k127_7076188_7 Sulfurtransferase TusA K04085 - - 0.000000000000000000000000000000001958 129.0
REGS2_k127_7076188_8 - - - - 0.000000000000000000000000000003857 124.0
REGS2_k127_7076188_9 - - - - 0.00000000001709 69.0
REGS2_k127_7089177_0 Pfam:Methyltransf_26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 592.0
REGS2_k127_7089177_1 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 474.0
REGS2_k127_7089177_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 377.0
REGS2_k127_7169374_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 545.0
REGS2_k127_7169374_1 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 344.0
REGS2_k127_7173799_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 510.0
REGS2_k127_7173799_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 412.0
REGS2_k127_7173799_2 PFAM import inner membrane translocase subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 361.0
REGS2_k127_7173799_3 protein conserved in bacteria K03690 - - 0.000000000000000000000000000000000000000000000000000006361 193.0
REGS2_k127_7177758_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1454.0
REGS2_k127_7177758_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 2.885e-264 820.0
REGS2_k127_7177758_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 569.0
REGS2_k127_7177758_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 481.0
REGS2_k127_7177758_4 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 389.0
REGS2_k127_7177758_5 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 369.0
REGS2_k127_7177758_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000006688 171.0
REGS2_k127_7177758_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000005606 88.0
REGS2_k127_7260997_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.052e-248 771.0
REGS2_k127_7340690_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.484e-295 909.0
REGS2_k127_7340690_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 575.0
REGS2_k127_7340690_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000389 246.0
REGS2_k127_7340690_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000006127 206.0
REGS2_k127_7340690_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
REGS2_k127_7340690_5 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000003097 154.0
REGS2_k127_7340690_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.000000000000000000000000000003966 128.0
REGS2_k127_7356119_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 566.0
REGS2_k127_7356119_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 531.0
REGS2_k127_7356119_2 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001801 277.0
REGS2_k127_7356119_3 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000631 271.0
REGS2_k127_7394517_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 600.0
REGS2_k127_7394517_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 542.0
REGS2_k127_7394517_2 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 433.0
REGS2_k127_7400674_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 524.0
REGS2_k127_7400674_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 445.0
REGS2_k127_7400674_2 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 288.0
REGS2_k127_7400674_3 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 285.0
REGS2_k127_7400674_4 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000003668 143.0
REGS2_k127_7400674_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000007966 95.0
REGS2_k127_7428557_0 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 599.0
REGS2_k127_7428557_1 response regulator K19623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 271.0
REGS2_k127_7428557_2 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000001833 185.0
REGS2_k127_7446705_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 602.0
REGS2_k127_7446705_1 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 497.0
REGS2_k127_7446705_2 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 392.0
REGS2_k127_7446705_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 281.0
REGS2_k127_7446705_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000006023 248.0
REGS2_k127_7446705_5 Protein of unknown function (DUF494) K03747 - - 0.0000000000000000000000000000000000000000000000000000000007395 204.0
REGS2_k127_7462192_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 428.0
REGS2_k127_7462192_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 400.0
REGS2_k127_7462192_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 370.0
REGS2_k127_7462192_3 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000004846 235.0
REGS2_k127_7462192_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000006668 215.0
REGS2_k127_747159_0 PFAM type II and III secretion system protein K02453,K12282 - - 1.393e-204 650.0
REGS2_k127_747159_1 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 459.0
REGS2_k127_747159_10 Pilus assembly protein PilX K12286 - - 0.0000000001426 68.0
REGS2_k127_747159_11 Concanavalin A-like lectin/glucanases superfamily K12287 - - 0.000009166 53.0
REGS2_k127_747159_2 Pilus assembly protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 367.0
REGS2_k127_747159_3 Prokaryotic N-terminal methylation motif K12285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 304.0
REGS2_k127_747159_4 Fimbrial assembly protein (PilN) - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
REGS2_k127_747159_5 carbon utilization K12280 - - 0.00000000000000000000000000000000000000000000000000000000000000008157 229.0
REGS2_k127_747159_6 Tetratricopeptide repeat K12284 - - 0.00000000000000000000000000000000000000000000000000000000192 216.0
REGS2_k127_747159_7 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000004209 123.0
REGS2_k127_747159_8 Tfp pilus assembly protein FimT K10926 - - 0.0000000000000000000001566 104.0
REGS2_k127_747159_9 - K12281 - - 0.00000000000000001203 90.0
REGS2_k127_7497641_0 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 416.0
REGS2_k127_7497641_1 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000007993 195.0
REGS2_k127_750629_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 443.0
REGS2_k127_750629_1 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000785 271.0
REGS2_k127_750629_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006826 265.0
REGS2_k127_750629_3 - - - - 0.000000000000000000000000000005995 124.0
REGS2_k127_750629_4 virion core protein, lumpy skin disease virus - - - 0.0000006963 61.0
REGS2_k127_7649480_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 466.0
REGS2_k127_7649480_1 receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 424.0
REGS2_k127_7649480_2 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 283.0
REGS2_k127_7649480_3 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002121 281.0
REGS2_k127_7649480_4 Cell division protein ZapA K09888 - - 0.0000000000000000000000000000000000000000000000002828 177.0
REGS2_k127_7649480_5 - - - - 0.0000000000000000000000000000000000000000000004271 173.0
REGS2_k127_7649480_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000001007 159.0
REGS2_k127_7649480_7 - - - - 0.00000000000006455 73.0
REGS2_k127_7775054_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.171e-256 792.0
REGS2_k127_7775054_1 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
REGS2_k127_7775054_2 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000002318 171.0
REGS2_k127_7775054_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 0.000000000000000000000000000000006869 129.0
REGS2_k127_7779202_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.374e-315 977.0
REGS2_k127_7779202_1 (GGDEF) domain - - - 3.892e-214 687.0
REGS2_k127_7779202_2 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 587.0
REGS2_k127_7779202_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 428.0
REGS2_k127_7779202_4 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 339.0
REGS2_k127_7779202_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000004249 162.0
REGS2_k127_7779202_6 NMT1-like family K02051 - - 0.00000000000000001018 92.0
REGS2_k127_7779202_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000158 73.0
REGS2_k127_7780368_0 von Willebrand factor, type A - - - 7.555e-301 939.0
REGS2_k127_7780368_1 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 5.369e-218 677.0
REGS2_k127_7780368_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 541.0
REGS2_k127_7780368_3 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 323.0
REGS2_k127_7780368_4 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 320.0
REGS2_k127_7780368_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 291.0
REGS2_k127_7780368_6 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000004359 139.0
REGS2_k127_7780368_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000001874 112.0
REGS2_k127_7783075_0 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 409.0
REGS2_k127_7783075_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 324.0
REGS2_k127_7783075_2 Histidine kinase K11617 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001164 255.0
REGS2_k127_7783075_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000001337 193.0
REGS2_k127_7783075_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000007351 169.0
REGS2_k127_7783075_5 chemotaxis - - - 0.000000004634 69.0
REGS2_k127_7783075_6 - - - - 0.00005622 48.0
REGS2_k127_7787220_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1193.0
REGS2_k127_7787220_1 Polysulphide reductase, NrfD K00185 - - 4.413e-286 880.0
REGS2_k127_7787220_10 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 357.0
REGS2_k127_7787220_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 308.0
REGS2_k127_7787220_12 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 303.0
REGS2_k127_7787220_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 300.0
REGS2_k127_7787220_14 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003909 283.0
REGS2_k127_7787220_15 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000000007829 181.0
REGS2_k127_7787220_16 - - - - 0.000000000000000000000000000000000000000000008111 166.0
REGS2_k127_7787220_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000007655 153.0
REGS2_k127_7787220_18 DUF167 K09131 - - 0.000000000000000007569 83.0
REGS2_k127_7787220_19 - - - - 0.0000000000000002336 79.0
REGS2_k127_7787220_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 7.986e-267 828.0
REGS2_k127_7787220_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.426e-224 701.0
REGS2_k127_7787220_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 558.0
REGS2_k127_7787220_5 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 545.0
REGS2_k127_7787220_6 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 455.0
REGS2_k127_7787220_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 389.0
REGS2_k127_7787220_8 Glutathione S-transferase, C-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 362.0
REGS2_k127_7787220_9 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
REGS2_k127_7798334_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.743e-275 849.0
REGS2_k127_7798334_1 SurA N-terminal domain K03770 - 5.2.1.8 1.406e-222 706.0
REGS2_k127_7798334_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000559 163.0
REGS2_k127_7798334_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000005112 152.0
REGS2_k127_7798334_4 - - - - 0.0000000000000000001914 89.0
REGS2_k127_7804741_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 2.035e-232 725.0
REGS2_k127_7804741_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 400.0
REGS2_k127_7805306_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 430.0
REGS2_k127_7805306_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 426.0
REGS2_k127_7805306_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 352.0
REGS2_k127_7813217_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 517.0
REGS2_k127_7813217_1 PFAM Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 260.0
REGS2_k127_7813217_2 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001559 252.0
REGS2_k127_7813217_3 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001655 243.0
REGS2_k127_7813217_4 - - - - 0.000000000000000000000000000000000000000000000000002717 188.0
REGS2_k127_7813217_5 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000004699 164.0
REGS2_k127_7813217_6 - - - - 0.000000000000005759 76.0
REGS2_k127_7813217_7 Beta-xylanase K01181 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0016052,GO:0016787,GO:0016798,GO:0030312,GO:0031176,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:0071944,GO:0097599,GO:1901575 3.2.1.8 0.00000001572 58.0
REGS2_k127_7824708_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1044.0
REGS2_k127_7824708_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 607.0
REGS2_k127_7824708_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 492.0
REGS2_k127_7824708_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 471.0
REGS2_k127_7824708_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 376.0
REGS2_k127_7824708_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
REGS2_k127_7824708_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000004567 259.0
REGS2_k127_7824708_7 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000000000000000000000000000000000006816 185.0
REGS2_k127_7842559_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1691.0
REGS2_k127_7842559_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 6.362e-286 887.0
REGS2_k127_7842559_10 Prokaryotic N-terminal methylation motif K10924 - - 0.0000000000000000000001255 103.0
REGS2_k127_7842559_11 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid K19164 - - 0.0000000000000000000003101 98.0
REGS2_k127_7842559_12 Transcriptional regulator - - - 0.0000000000001806 74.0
REGS2_k127_7842559_2 Domain of unknown function (DUF4139) - - - 1.42e-237 741.0
REGS2_k127_7842559_3 Sugar (and other) transporter - - - 1.054e-229 717.0
REGS2_k127_7842559_4 PFAM Type II secretion system F domain K02455,K12278 - - 1.063e-202 638.0
REGS2_k127_7842559_5 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
REGS2_k127_7842559_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001858 255.0
REGS2_k127_7842559_7 general secretion pathway protein K02456,K02457,K02458,K10930,K12285 - - 0.0000000000000000000000000000000000000000000000000000000001021 210.0
REGS2_k127_7842559_8 - - - - 0.00000000000000000000000000000000000000725 149.0
REGS2_k127_7842559_9 PFAM CcdB protein K19163 - - 0.00000000000000000000000000000000000003228 145.0
REGS2_k127_7843663_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.433e-286 891.0
REGS2_k127_7843663_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 484.0
REGS2_k127_7843663_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 443.0
REGS2_k127_7843663_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 366.0
REGS2_k127_7843663_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000002368 63.0
REGS2_k127_78566_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 513.0
REGS2_k127_78566_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 417.0
REGS2_k127_78566_2 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 271.0
REGS2_k127_78566_3 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002676 225.0
REGS2_k127_7860467_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 404.0
REGS2_k127_7860467_1 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 349.0
REGS2_k127_7860467_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 300.0
REGS2_k127_7860467_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
REGS2_k127_7860467_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
REGS2_k127_7860467_5 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000000001373 148.0
REGS2_k127_7860467_6 transport-associated - - - 0.000000000000000000000000000000002519 136.0
REGS2_k127_7860467_7 Protein of unknown function (DUF971) - - - 0.000000007456 57.0
REGS2_k127_7897710_0 Bacterial-like globin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 361.0
REGS2_k127_7897710_1 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 332.0
REGS2_k127_7897710_2 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000009232 201.0
REGS2_k127_7897710_3 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
REGS2_k127_7897710_4 GTP-binding domain protein K06945 - - 0.0000000000000000000000000000000000000000000000000000002909 198.0
REGS2_k127_7897710_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000006871 135.0
REGS2_k127_7897710_6 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000001074 114.0
REGS2_k127_7897710_7 - - - - 0.000000001597 67.0
REGS2_k127_7907758_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 309.0
REGS2_k127_7907758_1 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002096 245.0
REGS2_k127_7907758_2 Ribosomal protein L9, N-terminal domain K02939 - - 0.000000000000000000000000000000000000000000000000000000000000003317 219.0
REGS2_k127_7907758_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000000009948 217.0
REGS2_k127_7907758_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000006092 152.0
REGS2_k127_7907758_5 DNA replication, synthesis of RNA primer K02686 - - 0.000000000000000000000000002596 114.0
REGS2_k127_7907758_6 PFAM CBS domain containing protein - - - 0.00000000000000000001675 99.0
REGS2_k127_7931080_0 PFAM aminotransferase class I and II K14267 - 2.6.1.17 1.692e-218 682.0
REGS2_k127_7931080_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 364.0
REGS2_k127_7931080_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 343.0
REGS2_k127_7931080_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 349.0
REGS2_k127_7945049_0 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 442.0
REGS2_k127_7945049_1 PFAM aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000002911 215.0
REGS2_k127_7945049_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000006206 153.0
REGS2_k127_7953883_0 Histidine kinase K19621 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 606.0
REGS2_k127_7953883_1 Methyltransferase domain K19620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 551.0
REGS2_k127_7953883_2 response regulator K19622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 422.0
REGS2_k127_7953883_3 response regulator K19623 - - 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
REGS2_k127_7955678_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 3.387e-278 859.0
REGS2_k127_7955678_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.791e-250 788.0
REGS2_k127_7955678_10 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000004603 124.0
REGS2_k127_7955678_2 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 521.0
REGS2_k127_7955678_3 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 424.0
REGS2_k127_7955678_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000001243 246.0
REGS2_k127_7955678_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000005105 228.0
REGS2_k127_7955678_6 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000000000000000000000000002869 223.0
REGS2_k127_7955678_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000003346 217.0
REGS2_k127_7955678_8 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000002104 166.0
REGS2_k127_7955678_9 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000004454 160.0
REGS2_k127_7959303_0 protein synthesis factor, GTP-binding K06207 - - 1.814e-313 967.0
REGS2_k127_7959303_1 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 6.327e-218 689.0
REGS2_k127_7959303_2 PFAM iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 409.0
REGS2_k127_7959303_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 366.0
REGS2_k127_7959303_4 PFAM ferric-uptake regulator K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009121 241.0
REGS2_k127_7959303_5 Cupredoxin-like domain - - - 0.000000000000000000000000000000000000000001726 160.0
REGS2_k127_7959503_0 NeuB family K03856 - 2.5.1.54 6.312e-198 619.0
REGS2_k127_7959503_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 585.0
REGS2_k127_7959503_2 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000002183 216.0
REGS2_k127_7959503_3 Methyltransferase type 11 - - - 0.0000000000000000000000000534 110.0
REGS2_k127_7992216_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 595.0
REGS2_k127_7992216_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 442.0
REGS2_k127_7992216_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 350.0
REGS2_k127_7992216_3 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 296.0
REGS2_k127_7992216_4 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001102 279.0
REGS2_k127_7992216_5 crp fnr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
REGS2_k127_7992216_6 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000001939 215.0
REGS2_k127_7992216_7 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000009398 181.0
REGS2_k127_8016199_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 497.0
REGS2_k127_8016199_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 421.0
REGS2_k127_8145687_0 Likely ribonuclease with RNase H fold. K06959 - - 0.0 1295.0
REGS2_k127_8145687_1 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 1.196e-299 921.0
REGS2_k127_8145687_2 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 8.225e-270 837.0
REGS2_k127_8145687_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 551.0
REGS2_k127_8145687_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 287.0
REGS2_k127_8197467_0 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000000000000000005204 234.0
REGS2_k127_8197467_1 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000002479 192.0
REGS2_k127_8197467_2 Cas6 Crispr - - - 0.0000000000000000000000000000000000001048 145.0
REGS2_k127_8197467_3 - - - - 0.0000000000000000000000000000000000008373 142.0
REGS2_k127_8242822_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1058.0
REGS2_k127_8242822_1 Histidine kinase - - - 3.929e-233 730.0
REGS2_k127_8242822_2 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 587.0
REGS2_k127_8242822_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 510.0
REGS2_k127_8242822_4 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003521 263.0
REGS2_k127_8242822_5 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000002071 208.0
REGS2_k127_8242822_6 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000003656 192.0
REGS2_k127_8250867_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1117.0
REGS2_k127_8250867_1 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 445.0
REGS2_k127_8250867_2 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 308.0
REGS2_k127_8250867_3 helix_turn_helix, Lux Regulon K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
REGS2_k127_8282800_0 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 477.0
REGS2_k127_8282800_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000001871 230.0
REGS2_k127_8282800_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000341 144.0
REGS2_k127_835981_0 Protein of unknown function - - - 0.0 1259.0
REGS2_k127_835981_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.697e-264 827.0
REGS2_k127_835981_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 2.206e-218 681.0
REGS2_k127_835981_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 3.376e-204 647.0
REGS2_k127_835981_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 469.0
REGS2_k127_835981_5 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000003683 135.0
REGS2_k127_8410600_0 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 604.0
REGS2_k127_8410600_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 424.0
REGS2_k127_8410600_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 387.0
REGS2_k127_8410600_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 318.0
REGS2_k127_84402_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1595.0
REGS2_k127_84402_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 409.0
REGS2_k127_84402_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000003157 54.0
REGS2_k127_8477329_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 7.012e-250 775.0
REGS2_k127_8477329_1 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 1.342e-237 738.0
REGS2_k127_8477329_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 428.0
REGS2_k127_8477329_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 332.0
REGS2_k127_8477329_4 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
REGS2_k127_8513793_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 5.382e-207 651.0
REGS2_k127_8513793_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 501.0
REGS2_k127_8513793_2 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 432.0
REGS2_k127_8513793_3 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 273.0
REGS2_k127_8513793_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000002908 196.0
REGS2_k127_8513793_5 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000000000000000000000000000003882 188.0
REGS2_k127_8513793_6 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000133 113.0
REGS2_k127_8586955_0 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 3.751e-206 647.0
REGS2_k127_8586955_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 488.0
REGS2_k127_8586955_2 LysR substrate binding domain K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 400.0
REGS2_k127_8586955_3 membrane - - - 0.0000000000000000000000000000000000000000001154 162.0
REGS2_k127_8586955_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000002988 158.0
REGS2_k127_8586955_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000000001509 140.0
REGS2_k127_868797_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 2.219e-256 798.0
REGS2_k127_868797_1 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 469.0
REGS2_k127_868797_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000117 285.0
REGS2_k127_868797_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 268.0
REGS2_k127_868797_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002493 270.0
REGS2_k127_868797_5 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.0005464 46.0
REGS2_k127_873197_0 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 520.0
REGS2_k127_873197_1 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000002331 211.0
REGS2_k127_873197_2 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000006329 117.0
REGS2_k127_878423_0 PFAM cytochrome c biogenesis protein transmembrane region - - - 3.092e-278 865.0
REGS2_k127_878423_1 NADH flavin oxidoreductase NADH oxidase K10680 - - 1.162e-197 619.0
REGS2_k127_878423_2 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 505.0
REGS2_k127_878423_3 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 312.0
REGS2_k127_878423_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 306.0
REGS2_k127_878423_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 294.0
REGS2_k127_878423_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002647 272.0
REGS2_k127_878423_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001074 266.0
REGS2_k127_878423_8 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00000000000000000000000000000000002746 134.0
REGS2_k127_878423_9 Flagellar regulator YcgR - - - 0.00000000000000000007057 99.0
REGS2_k127_8945_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 398.0
REGS2_k127_8945_1 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 390.0
REGS2_k127_8945_2 PFAM porin Gram-negative type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
REGS2_k127_904184_0 TonB dependent receptor K02014 - - 0.0 1124.0
REGS2_k127_904184_1 Copper chaperone PCu(A)C K09796 - - 0.000000000000000007071 87.0
REGS2_k127_905918_0 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 407.0
REGS2_k127_905918_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 287.0
REGS2_k127_905918_2 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000803 275.0
REGS2_k127_913569_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 308.0
REGS2_k127_913569_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000006222 237.0
REGS2_k127_913569_2 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
REGS2_k127_913569_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000001696 205.0
REGS2_k127_913569_4 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000000000000000000006166 199.0
REGS2_k127_915713_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 496.0
REGS2_k127_915713_1 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
REGS2_k127_915713_2 translation initiation factor activity - - - 0.0000000000000000000000000001251 126.0
REGS2_k127_971161_0 Protein of unknown function, DUF255 K06888 - - 7.727e-301 936.0
REGS2_k127_971161_1 PFAM cytochrome c oxidase subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 572.0
REGS2_k127_971161_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 499.0
REGS2_k127_971161_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 355.0
REGS2_k127_971161_4 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000007491 180.0
REGS2_k127_975735_0 FAD dependent oxidoreductase K00313 - - 1.848e-232 724.0
REGS2_k127_975735_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 485.0
REGS2_k127_975735_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 323.0
REGS2_k127_975735_3 ATP-binding protein K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 291.0
REGS2_k127_975735_4 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 286.0
REGS2_k127_975735_5 - - - - 0.0000000000000000000000000000000000000000000000000000000434 201.0
REGS2_k127_975735_6 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.000000000000000000000000000000000000000000000000672 175.0
REGS2_k127_975735_7 Ferredoxin - - - 0.00000000000000000000000000000000000000001716 155.0
REGS2_k127_975735_8 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02019 - - 0.00000000000000000000000000000003222 134.0
REGS2_k127_975735_9 - - - - 0.000000000000000026 86.0
REGS2_k127_988582_0 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 438.0
REGS2_k127_988582_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008413 245.0
REGS2_k127_988582_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000001769 186.0