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Overview

ID MAG03331
Name REGS2_bin.20
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family GWC2-71-9
Genus DATLWA01
Species DATLWA01 sp041487875
Assembly information
Completeness (%) 95.16
Contamination (%) 1.79
GC content (%) 69.0
N50 (bp) 22,237
Genome size (bp) 2,720,227

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2414

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1007183_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 291.0
REGS2_k127_1007183_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000001408 177.0
REGS2_k127_1041809_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.305e-219 689.0
REGS2_k127_1041809_1 von Willebrand factor (vWF) type A domain - - - 2.265e-207 653.0
REGS2_k127_1041809_10 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 408.0
REGS2_k127_1041809_11 4Fe-4S binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 375.0
REGS2_k127_1041809_12 mannose metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 372.0
REGS2_k127_1041809_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 342.0
REGS2_k127_1041809_14 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 344.0
REGS2_k127_1041809_15 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 340.0
REGS2_k127_1041809_16 Cytochrome c K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 317.0
REGS2_k127_1041809_17 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 296.0
REGS2_k127_1041809_18 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003475 263.0
REGS2_k127_1041809_19 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003645 272.0
REGS2_k127_1041809_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 602.0
REGS2_k127_1041809_20 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000004836 252.0
REGS2_k127_1041809_21 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000001576 215.0
REGS2_k127_1041809_22 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000772 211.0
REGS2_k127_1041809_23 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000005579 209.0
REGS2_k127_1041809_24 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000003338 194.0
REGS2_k127_1041809_25 response regulator K07782 - - 0.000000000000000000000000000000000000000000003576 171.0
REGS2_k127_1041809_26 Glutathione peroxidase - - - 0.000000000000000000000000000000000000001806 152.0
REGS2_k127_1041809_27 PFAM FAD binding domain K11472 - - 0.000000000000000000000000000000000000002115 162.0
REGS2_k127_1041809_28 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000008502 161.0
REGS2_k127_1041809_29 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000001429 157.0
REGS2_k127_1041809_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 554.0
REGS2_k127_1041809_30 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.00000000000000000000000000000000006798 147.0
REGS2_k127_1041809_31 NlpC/P60 family - - - 0.0000000000000000000000000000000001486 150.0
REGS2_k127_1041809_32 HD domain - - - 0.00000000000000000000000000000006096 132.0
REGS2_k127_1041809_33 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.0000000000000000000000364 111.0
REGS2_k127_1041809_34 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000002312 102.0
REGS2_k127_1041809_35 PFAM band 7 protein - - - 0.00000000000002191 84.0
REGS2_k127_1041809_37 YbbR-like protein - - - 0.00002506 55.0
REGS2_k127_1041809_4 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 537.0
REGS2_k127_1041809_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 508.0
REGS2_k127_1041809_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 462.0
REGS2_k127_1041809_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 445.0
REGS2_k127_1041809_8 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 440.0
REGS2_k127_1041809_9 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
REGS2_k127_1071038_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 535.0
REGS2_k127_1071038_1 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 487.0
REGS2_k127_1071038_10 Histidine kinase K02660,K11525 - - 0.000000000000000000000000001034 114.0
REGS2_k127_1071038_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 503.0
REGS2_k127_1071038_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 456.0
REGS2_k127_1071038_4 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 468.0
REGS2_k127_1071038_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 415.0
REGS2_k127_1071038_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000003728 254.0
REGS2_k127_1071038_7 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001324 230.0
REGS2_k127_1071038_8 DinB superfamily - - - 0.00000000000000000000000000000000000000000000007651 177.0
REGS2_k127_1071038_9 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000008395 186.0
REGS2_k127_1098505_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
REGS2_k127_1098505_1 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000008478 171.0
REGS2_k127_1098505_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000005564 128.0
REGS2_k127_1098611_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000005519 151.0
REGS2_k127_1098611_1 - - - - 0.0000000000000000000000000000000003593 136.0
REGS2_k127_1098611_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000002049 127.0
REGS2_k127_1098611_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000002854 62.0
REGS2_k127_1098611_4 carboxypeptidase Z K01292,K01294,K07752,K13022,K21392 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0004185,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0031012,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044421,GO:0051604,GO:0070008,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.10,3.4.17.22,3.4.17.3 0.0000004322 59.0
REGS2_k127_1105994_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000006229 194.0
REGS2_k127_1105994_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000001597 134.0
REGS2_k127_117823_0 penicillin binding K05367 - 2.4.1.129 1.408e-285 899.0
REGS2_k127_117823_1 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001639 252.0
REGS2_k127_1182246_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 569.0
REGS2_k127_1182246_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 495.0
REGS2_k127_1182246_2 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 313.0
REGS2_k127_1182246_3 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 325.0
REGS2_k127_1182246_4 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000008052 203.0
REGS2_k127_1182246_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000001305 142.0
REGS2_k127_1182246_7 domain protein K12287,K12549,K13735,K20276 - - 0.0001523 55.0
REGS2_k127_1201883_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 465.0
REGS2_k127_1201883_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
REGS2_k127_1201883_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004076 258.0
REGS2_k127_1201883_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000003322 245.0
REGS2_k127_1201883_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000008939 178.0
REGS2_k127_1201883_5 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000003531 159.0
REGS2_k127_1201883_6 - - - - 0.000000000009521 66.0
REGS2_k127_1201883_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0001268 44.0
REGS2_k127_1216005_0 Tricorn protease homolog K08676 - - 0.0 1387.0
REGS2_k127_1216005_1 phosphorelay signal transduction system K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 387.0
REGS2_k127_1216005_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000001048 133.0
REGS2_k127_1216005_3 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000007075 138.0
REGS2_k127_1216005_4 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000003078 131.0
REGS2_k127_1216005_5 Endonuclease related to archaeal Holliday junction resolvase - - - 0.000000000000000000000000000124 119.0
REGS2_k127_1216005_8 peptidyl-tyrosine sulfation - - - 0.00000003533 63.0
REGS2_k127_1230683_0 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 270.0
REGS2_k127_1230683_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000005242 126.0
REGS2_k127_1265525_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 548.0
REGS2_k127_1265525_1 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.000000000000000000001023 105.0
REGS2_k127_1265525_2 - - - - 0.00000000000000003135 90.0
REGS2_k127_1265525_3 cell adhesion involved in biofilm formation - - - 0.0000000008535 70.0
REGS2_k127_1278221_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 634.0
REGS2_k127_1278221_1 Major facilitator Superfamily K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 589.0
REGS2_k127_1278221_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 312.0
REGS2_k127_1278221_11 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002121 258.0
REGS2_k127_1278221_12 flavoprotein involved in K transport K11816 - 1.14.13.168 0.00000000000000000000000000000000000000000000000000000000000000001097 238.0
REGS2_k127_1278221_13 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000005672 243.0
REGS2_k127_1278221_14 ABC transporter K01990 - - 0.00000000000000000000000000000000000004826 151.0
REGS2_k127_1278221_15 - - - - 0.000000000000001963 87.0
REGS2_k127_1278221_16 PFAM SH3, type 3 - - - 0.00000000005031 74.0
REGS2_k127_1278221_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00001736 49.0
REGS2_k127_1278221_2 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 516.0
REGS2_k127_1278221_3 alpha-galactosidase activity K01189,K01204,K07407 - 3.2.1.22,3.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 457.0
REGS2_k127_1278221_4 fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 460.0
REGS2_k127_1278221_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 371.0
REGS2_k127_1278221_6 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 369.0
REGS2_k127_1278221_7 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 341.0
REGS2_k127_1278221_8 Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 308.0
REGS2_k127_1278221_9 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 323.0
REGS2_k127_134513_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000006899 228.0
REGS2_k127_134513_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000001484 222.0
REGS2_k127_1368910_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000168 201.0
REGS2_k127_1368910_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000006379 170.0
REGS2_k127_137137_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 494.0
REGS2_k127_137137_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 391.0
REGS2_k127_137137_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000004321 62.0
REGS2_k127_137137_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 321.0
REGS2_k127_137137_3 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001282 268.0
REGS2_k127_137137_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000001438 203.0
REGS2_k127_137137_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000108 164.0
REGS2_k127_137137_6 STAS domain K04749 - - 0.00000000000000000000000000000000000008425 156.0
REGS2_k127_137137_7 sigma factor antagonist activity K04757,K06379,K08282 - 2.7.11.1 0.000000000000000001205 97.0
REGS2_k127_137137_8 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000331 94.0
REGS2_k127_137137_9 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000003451 88.0
REGS2_k127_1426007_0 Belongs to the ClpA ClpB family K03696 - - 2.139e-307 964.0
REGS2_k127_1426007_1 Surface antigen K07277 - - 7.113e-230 741.0
REGS2_k127_1426007_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 300.0
REGS2_k127_1426007_11 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 290.0
REGS2_k127_1426007_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 308.0
REGS2_k127_1426007_13 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007736 293.0
REGS2_k127_1426007_14 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000001127 263.0
REGS2_k127_1426007_15 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000003956 235.0
REGS2_k127_1426007_16 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000001186 163.0
REGS2_k127_1426007_17 - - - - 0.000000000000000000000000000000000000000008391 174.0
REGS2_k127_1426007_18 - - - - 0.00000000000000000000000000000000000000009464 161.0
REGS2_k127_1426007_19 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000003875 150.0
REGS2_k127_1426007_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 9.379e-203 653.0
REGS2_k127_1426007_20 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000001811 144.0
REGS2_k127_1426007_21 UvrB/uvrC motif K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000003581 93.0
REGS2_k127_1426007_22 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000138 94.0
REGS2_k127_1426007_23 Belongs to the UPF0434 family K09791 - - 0.000000000000000615 80.0
REGS2_k127_1426007_24 long-chain fatty acid transporting porin activity - - - 0.000001323 60.0
REGS2_k127_1426007_25 - - - - 0.0003759 47.0
REGS2_k127_1426007_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 511.0
REGS2_k127_1426007_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 484.0
REGS2_k127_1426007_5 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 458.0
REGS2_k127_1426007_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 434.0
REGS2_k127_1426007_7 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 414.0
REGS2_k127_1426007_8 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 343.0
REGS2_k127_1426007_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 327.0
REGS2_k127_1437385_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 429.0
REGS2_k127_1437385_1 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000005298 192.0
REGS2_k127_1437385_2 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.0000000000000000000000000000000000000002534 161.0
REGS2_k127_1437385_3 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000001151 147.0
REGS2_k127_145325_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 304.0
REGS2_k127_145325_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004645 267.0
REGS2_k127_145325_2 transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000009658 222.0
REGS2_k127_145325_3 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000009616 207.0
REGS2_k127_145325_4 PcrB family K07094 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.0000000000000000000000000000000000000000002721 172.0
REGS2_k127_145325_5 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000006515 80.0
REGS2_k127_145325_6 Recombination factor protein RarA K07478 - - 0.0000000000001436 76.0
REGS2_k127_145325_7 - - - - 0.00004328 51.0
REGS2_k127_145325_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0004857 43.0
REGS2_k127_151740_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.485e-268 833.0
REGS2_k127_151740_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.093e-231 753.0
REGS2_k127_151740_10 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004023 282.0
REGS2_k127_151740_11 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000466 281.0
REGS2_k127_151740_12 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000004217 263.0
REGS2_k127_151740_13 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006736 259.0
REGS2_k127_151740_14 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000002485 252.0
REGS2_k127_151740_15 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000001261 231.0
REGS2_k127_151740_16 isoleucine patch - - - 0.000000000000000000000000000000000000000000000000007317 205.0
REGS2_k127_151740_17 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000004871 168.0
REGS2_k127_151740_18 FHA domain - - - 0.000000000000000000000000001624 125.0
REGS2_k127_151740_19 peptidyl-tyrosine sulfation - - - 0.00000000000000003159 98.0
REGS2_k127_151740_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 549.0
REGS2_k127_151740_20 - - - - 0.0000000000000002601 81.0
REGS2_k127_151740_21 Tfp pilus assembly protein FimV - - - 0.000000000002484 79.0
REGS2_k127_151740_22 - - - - 0.00000000001646 69.0
REGS2_k127_151740_23 Trypsin domain PDZ domain protein - - - 0.0000000002778 73.0
REGS2_k127_151740_24 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000004492 69.0
REGS2_k127_151740_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 471.0
REGS2_k127_151740_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 415.0
REGS2_k127_151740_5 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 434.0
REGS2_k127_151740_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 358.0
REGS2_k127_151740_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 356.0
REGS2_k127_151740_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 323.0
REGS2_k127_151740_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 316.0
REGS2_k127_154696_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.258e-227 760.0
REGS2_k127_154696_1 aminopeptidase activity K05994 - 3.4.11.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 569.0
REGS2_k127_154696_10 - - - - 0.0000000000000000000000000234 110.0
REGS2_k127_154696_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000006941 95.0
REGS2_k127_154696_12 Periplasmic component of the Tol biopolymer transport system - - - 0.0000008716 61.0
REGS2_k127_154696_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 546.0
REGS2_k127_154696_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 469.0
REGS2_k127_154696_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 449.0
REGS2_k127_154696_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 385.0
REGS2_k127_154696_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000001198 221.0
REGS2_k127_154696_7 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000008229 181.0
REGS2_k127_154696_8 - - - - 0.0000000000000000000000000000000008474 145.0
REGS2_k127_154696_9 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000008204 134.0
REGS2_k127_1717041_0 TonB dependent receptor - - - 0.0000000000000000000000000000005484 140.0
REGS2_k127_1785856_0 Atp-dependent helicase - - - 4.158e-315 987.0
REGS2_k127_1785856_1 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 533.0
REGS2_k127_1785856_10 - - - - 0.0001278 54.0
REGS2_k127_1785856_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 451.0
REGS2_k127_1785856_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008261 292.0
REGS2_k127_1785856_4 DEAD DEAH box helicase K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003683 247.0
REGS2_k127_1785856_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000001367 220.0
REGS2_k127_1785856_6 Thioesterase superfamily K07107 - - 0.000000000000000000000003245 108.0
REGS2_k127_1785856_7 chemotaxis protein K03406 - - 0.0000000000000000000878 105.0
REGS2_k127_1785856_8 Rdx family K07401 - - 0.000000000005436 67.0
REGS2_k127_1785856_9 Positively regulates the dhaKLM operon from a sigma-70 promoter K05880 GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000005755 58.0
REGS2_k127_1798483_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1144.0
REGS2_k127_1798483_1 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 9.331e-270 850.0
REGS2_k127_1798483_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 391.0
REGS2_k127_1798483_11 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 354.0
REGS2_k127_1798483_12 response to heat K03695,K03696,K03697,K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 351.0
REGS2_k127_1798483_13 Rho termination factor, RNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 341.0
REGS2_k127_1798483_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 328.0
REGS2_k127_1798483_15 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 325.0
REGS2_k127_1798483_16 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 332.0
REGS2_k127_1798483_17 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 325.0
REGS2_k127_1798483_18 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 314.0
REGS2_k127_1798483_19 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 299.0
REGS2_k127_1798483_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.473e-243 764.0
REGS2_k127_1798483_20 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 286.0
REGS2_k127_1798483_21 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000257 293.0
REGS2_k127_1798483_22 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001391 278.0
REGS2_k127_1798483_23 ABC 3 transport family K02075,K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001423 275.0
REGS2_k127_1798483_24 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003702 279.0
REGS2_k127_1798483_25 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
REGS2_k127_1798483_26 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
REGS2_k127_1798483_27 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005157 259.0
REGS2_k127_1798483_28 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000102 253.0
REGS2_k127_1798483_29 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000002682 234.0
REGS2_k127_1798483_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.232e-228 719.0
REGS2_k127_1798483_30 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004533 242.0
REGS2_k127_1798483_31 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000001815 229.0
REGS2_k127_1798483_32 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000005294 230.0
REGS2_k127_1798483_33 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000517 232.0
REGS2_k127_1798483_34 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000002011 211.0
REGS2_k127_1798483_35 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000003125 205.0
REGS2_k127_1798483_36 Heptosyltransferase II K02843 - - 0.0000000000000000000000000000000000000000000000000000006555 206.0
REGS2_k127_1798483_37 Tfp pilus assembly protein FimV K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000752 209.0
REGS2_k127_1798483_38 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000000000000002544 198.0
REGS2_k127_1798483_39 MoaC family K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000417 181.0
REGS2_k127_1798483_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 614.0
REGS2_k127_1798483_40 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000001155 177.0
REGS2_k127_1798483_41 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000002204 169.0
REGS2_k127_1798483_42 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002082 158.0
REGS2_k127_1798483_43 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000004448 154.0
REGS2_k127_1798483_44 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000001314 143.0
REGS2_k127_1798483_45 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000004682 139.0
REGS2_k127_1798483_46 integral membrane protein K07027 - - 0.000000000000000000000007012 114.0
REGS2_k127_1798483_47 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000004111 110.0
REGS2_k127_1798483_48 - - - - 0.00000000000000001646 89.0
REGS2_k127_1798483_49 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits - - - 0.00000000000001741 86.0
REGS2_k127_1798483_5 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 477.0
REGS2_k127_1798483_50 - - - - 0.000000000001714 74.0
REGS2_k127_1798483_51 Surface antigen - - - 0.0001134 54.0
REGS2_k127_1798483_52 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0009008 48.0
REGS2_k127_1798483_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 494.0
REGS2_k127_1798483_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 441.0
REGS2_k127_1798483_8 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 402.0
REGS2_k127_1798483_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 387.0
REGS2_k127_1811010_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 504.0
REGS2_k127_1811010_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 450.0
REGS2_k127_1811010_10 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003829 289.0
REGS2_k127_1811010_11 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003521 280.0
REGS2_k127_1811010_12 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000134 243.0
REGS2_k127_1811010_13 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000594 233.0
REGS2_k127_1811010_14 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000002714 199.0
REGS2_k127_1811010_15 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000407 194.0
REGS2_k127_1811010_16 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000009224 180.0
REGS2_k127_1811010_17 domain, Protein K01179,K07260,K13735 - 3.2.1.4,3.4.17.14 0.00000000000000000000000000000000000000000001404 173.0
REGS2_k127_1811010_18 Glycosyl transferase family 2 K08301 - - 0.00000000000000000000000000000000000000002826 170.0
REGS2_k127_1811010_19 POT family K03305 - - 0.000000000000000000000000000000000000005285 152.0
REGS2_k127_1811010_2 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 416.0
REGS2_k127_1811010_20 - - - - 0.0000000000000000000000000000000001865 151.0
REGS2_k127_1811010_21 - - - - 0.00000000000000000001656 96.0
REGS2_k127_1811010_22 - - - - 0.00000000000000009645 87.0
REGS2_k127_1811010_23 long-chain fatty acid transport protein - - - 0.0000000000815 74.0
REGS2_k127_1811010_24 Regulatory protein, FmdB family - - - 0.00000001421 61.0
REGS2_k127_1811010_25 - - - - 0.0001012 54.0
REGS2_k127_1811010_26 COG0457 FOG TPR repeat - - - 0.0001173 54.0
REGS2_k127_1811010_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 429.0
REGS2_k127_1811010_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 417.0
REGS2_k127_1811010_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 404.0
REGS2_k127_1811010_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 399.0
REGS2_k127_1811010_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 381.0
REGS2_k127_1811010_8 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 298.0
REGS2_k127_1811010_9 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001309 296.0
REGS2_k127_1811094_0 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 451.0
REGS2_k127_1811094_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 431.0
REGS2_k127_1811094_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 429.0
REGS2_k127_1811094_3 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
REGS2_k127_1811094_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 352.0
REGS2_k127_1811094_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004961 284.0
REGS2_k127_1811094_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000806 262.0
REGS2_k127_1811094_7 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000001703 169.0
REGS2_k127_1811094_8 - - - - 0.000000000000000000005233 98.0
REGS2_k127_1811094_9 major pilin protein fima - - - 0.0006317 43.0
REGS2_k127_1819175_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.798e-257 799.0
REGS2_k127_1819175_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.375e-248 775.0
REGS2_k127_1819175_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 335.0
REGS2_k127_1819175_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000009873 95.0
REGS2_k127_1838276_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 591.0
REGS2_k127_1838276_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 577.0
REGS2_k127_1838276_10 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 347.0
REGS2_k127_1838276_11 FecCD transport family K02013,K02015 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000004157 244.0
REGS2_k127_1838276_12 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000000000000000000006871 195.0
REGS2_k127_1838276_13 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000007812 193.0
REGS2_k127_1838276_14 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000002067 202.0
REGS2_k127_1838276_15 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.00000000000000000000000000000000000000000000000003396 190.0
REGS2_k127_1838276_16 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000006218 176.0
REGS2_k127_1838276_17 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000003946 170.0
REGS2_k127_1838276_18 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000001615 151.0
REGS2_k127_1838276_19 - - - - 0.0000000000000000000000000000000009116 143.0
REGS2_k127_1838276_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 544.0
REGS2_k127_1838276_20 Cytochrome c - - - 0.00000000000000000000000000000001476 141.0
REGS2_k127_1838276_21 Carboxypeptidase - - - 0.00000000000000000000000000201 117.0
REGS2_k127_1838276_22 PTS system sorbose-specific iic component K02795 - - 0.00000000000000000001521 104.0
REGS2_k127_1838276_23 phosphoenolpyruvate-dependent sugar phosphotransferase system K02784,K08485,K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000005084 93.0
REGS2_k127_1838276_24 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000001524 84.0
REGS2_k127_1838276_25 PTS system fructose IIA component K02744 - - 0.000000000000001957 81.0
REGS2_k127_1838276_26 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000008724 88.0
REGS2_k127_1838276_27 PFAM AIR synthase related protein K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 0.00000005841 56.0
REGS2_k127_1838276_28 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0004335 47.0
REGS2_k127_1838276_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 453.0
REGS2_k127_1838276_4 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 448.0
REGS2_k127_1838276_5 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 441.0
REGS2_k127_1838276_6 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 424.0
REGS2_k127_1838276_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 399.0
REGS2_k127_1838276_8 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 396.0
REGS2_k127_1838276_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 359.0
REGS2_k127_1862217_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 549.0
REGS2_k127_1862217_1 DNA polymerase alpha chain like domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 512.0
REGS2_k127_1862217_10 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000009091 246.0
REGS2_k127_1862217_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000004908 245.0
REGS2_k127_1862217_12 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000002142 244.0
REGS2_k127_1862217_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000002833 204.0
REGS2_k127_1862217_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000327 207.0
REGS2_k127_1862217_15 photosynthesis - - - 0.000000000000000000000000000000000000000000001891 169.0
REGS2_k127_1862217_16 ECF sigma factor K03088 - - 0.00000000000000000000000000000000002431 143.0
REGS2_k127_1862217_2 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 485.0
REGS2_k127_1862217_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 437.0
REGS2_k127_1862217_4 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 367.0
REGS2_k127_1862217_5 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 341.0
REGS2_k127_1862217_6 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 337.0
REGS2_k127_1862217_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009558 256.0
REGS2_k127_1862217_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000005101 255.0
REGS2_k127_1862217_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 240.0
REGS2_k127_1884760_0 cellulose binding - - - 1.644e-319 991.0
REGS2_k127_1908032_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1245.0
REGS2_k127_1908032_1 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004257 271.0
REGS2_k127_1908050_0 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002016 252.0
REGS2_k127_1908050_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 247.0
REGS2_k127_1914370_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.415e-296 935.0
REGS2_k127_1914370_1 Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 600.0
REGS2_k127_1914370_2 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 368.0
REGS2_k127_1914370_3 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 323.0
REGS2_k127_1914370_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001218 222.0
REGS2_k127_1914370_5 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000005488 143.0
REGS2_k127_1914370_6 LssY C-terminus K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000005 101.0
REGS2_k127_1914370_7 glycosyl transferase - - - 0.000000000000000003478 86.0
REGS2_k127_1960439_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0 1113.0
REGS2_k127_1960439_1 beta-galactosidase activity K01190 - 3.2.1.23 7.598e-309 966.0
REGS2_k127_1960439_10 - - - - 0.0000000000000002476 81.0
REGS2_k127_1960439_11 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.00000000253 70.0
REGS2_k127_1960439_12 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.000000156 60.0
REGS2_k127_1960439_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.088e-256 802.0
REGS2_k127_1960439_3 Domain of unknown function (DUF3536) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 527.0
REGS2_k127_1960439_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 507.0
REGS2_k127_1960439_5 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 464.0
REGS2_k127_1960439_6 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 390.0
REGS2_k127_1960439_7 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 327.0
REGS2_k127_1960439_8 - - - - 0.00000000000000000000001103 117.0
REGS2_k127_1960439_9 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0000000000000000003437 88.0
REGS2_k127_1973083_0 Heat shock 70 kDa protein K04043 - - 0.0 1011.0
REGS2_k127_1973083_1 GMC oxidoreductase - - - 2.437e-235 739.0
REGS2_k127_1973083_10 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002292 300.0
REGS2_k127_1973083_11 HAMP domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007853 287.0
REGS2_k127_1973083_12 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001526 279.0
REGS2_k127_1973083_13 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005539 274.0
REGS2_k127_1973083_14 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000006537 237.0
REGS2_k127_1973083_15 Cytochrome c K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000006348 223.0
REGS2_k127_1973083_16 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000008635 174.0
REGS2_k127_1973083_17 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000174 127.0
REGS2_k127_1973083_18 - - - - 0.000000000000000000000000009858 116.0
REGS2_k127_1973083_19 - - - - 0.00000000000000000007746 105.0
REGS2_k127_1973083_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.334e-203 666.0
REGS2_k127_1973083_20 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000354 83.0
REGS2_k127_1973083_21 Branched-chain amino acid transport system / permease component K10440,K17209 - - 0.00004755 54.0
REGS2_k127_1973083_3 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 400.0
REGS2_k127_1973083_4 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 362.0
REGS2_k127_1973083_5 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 359.0
REGS2_k127_1973083_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 340.0
REGS2_k127_1973083_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 331.0
REGS2_k127_1973083_8 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 324.0
REGS2_k127_1973083_9 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 291.0
REGS2_k127_1981622_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000001356 163.0
REGS2_k127_1981622_1 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000000002534 139.0
REGS2_k127_2004680_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 377.0
REGS2_k127_2004680_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 362.0
REGS2_k127_2004680_2 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000009066 132.0
REGS2_k127_2004680_3 TonB-dependent receptor K02014 - - 0.000000000000000001936 90.0
REGS2_k127_2004680_4 domain, Protein K07654 - 2.7.13.3 0.00006415 55.0
REGS2_k127_2081957_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 456.0
REGS2_k127_2081957_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000001026 244.0
REGS2_k127_2081957_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000115 214.0
REGS2_k127_2081957_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000001233 175.0
REGS2_k127_2081957_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000007005 181.0
REGS2_k127_2102238_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000377 265.0
REGS2_k127_2102238_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000228 243.0
REGS2_k127_2102238_2 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
REGS2_k127_2102238_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000003422 224.0
REGS2_k127_2102238_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000000000000000000007351 154.0
REGS2_k127_2102238_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000007813 162.0
REGS2_k127_2102238_6 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000004395 153.0
REGS2_k127_2102238_7 - - - - 0.000000000000000008524 98.0
REGS2_k127_2102238_8 - - - - 0.0000000708 60.0
REGS2_k127_2120561_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1300.0
REGS2_k127_2120561_1 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 457.0
REGS2_k127_2120561_2 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
REGS2_k127_2120561_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 300.0
REGS2_k127_2120561_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000003086 233.0
REGS2_k127_2120561_5 Putative phosphatase (DUF442) - - - 0.0000000004952 65.0
REGS2_k127_2218403_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.893e-306 952.0
REGS2_k127_2218403_1 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003357 244.0
REGS2_k127_2218403_10 transcriptional K02483,K07672 - - 0.00000000000000007545 85.0
REGS2_k127_2218403_11 involved in lipopolysaccharide synthesis - - - 0.000003005 54.0
REGS2_k127_2218403_2 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000008434 182.0
REGS2_k127_2218403_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000001287 158.0
REGS2_k127_2218403_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000006776 158.0
REGS2_k127_2218403_5 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000004725 135.0
REGS2_k127_2218403_6 quinone binding - - - 0.0000000000000000000003669 105.0
REGS2_k127_2218403_7 Redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000002319 97.0
REGS2_k127_2218403_8 - - - - 0.00000000000000000003022 92.0
REGS2_k127_2257011_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 552.0
REGS2_k127_2257011_1 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 489.0
REGS2_k127_2257011_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000001004 244.0
REGS2_k127_2257011_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000008107 143.0
REGS2_k127_2325244_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1020.0
REGS2_k127_2325244_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 320.0
REGS2_k127_2325244_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 316.0
REGS2_k127_2325244_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 294.0
REGS2_k127_2325244_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000002486 208.0
REGS2_k127_2325244_5 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000001526 179.0
REGS2_k127_2325244_6 Dehydrogenase - - - 0.0000000000000000000000000000000000000003633 167.0
REGS2_k127_2343525_0 Sortilin, neurotensin receptor 3, - - - 0.0 1290.0
REGS2_k127_2343525_1 FtsX-like permease family K02004 - - 1.014e-272 863.0
REGS2_k127_2343525_10 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 405.0
REGS2_k127_2343525_11 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 392.0
REGS2_k127_2343525_12 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
REGS2_k127_2343525_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 406.0
REGS2_k127_2343525_14 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 352.0
REGS2_k127_2343525_15 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 372.0
REGS2_k127_2343525_16 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 353.0
REGS2_k127_2343525_17 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 345.0
REGS2_k127_2343525_18 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 328.0
REGS2_k127_2343525_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 310.0
REGS2_k127_2343525_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 7.593e-228 743.0
REGS2_k127_2343525_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000026 277.0
REGS2_k127_2343525_21 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004677 262.0
REGS2_k127_2343525_22 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000006588 241.0
REGS2_k127_2343525_23 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000007573 207.0
REGS2_k127_2343525_24 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000129 184.0
REGS2_k127_2343525_25 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000004278 182.0
REGS2_k127_2343525_26 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000005777 147.0
REGS2_k127_2343525_27 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000007254 154.0
REGS2_k127_2343525_28 DNA polymerase K02347 - - 0.000000000000000000000000000000004406 132.0
REGS2_k127_2343525_29 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000001119 146.0
REGS2_k127_2343525_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.998e-221 691.0
REGS2_k127_2343525_30 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000005035 130.0
REGS2_k127_2343525_31 - - - - 0.00000000000000000000000000009642 124.0
REGS2_k127_2343525_32 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000004249 114.0
REGS2_k127_2343525_33 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000001855 101.0
REGS2_k127_2343525_34 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000007794 71.0
REGS2_k127_2343525_4 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 538.0
REGS2_k127_2343525_5 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 523.0
REGS2_k127_2343525_6 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 501.0
REGS2_k127_2343525_7 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 495.0
REGS2_k127_2343525_8 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 475.0
REGS2_k127_2343525_9 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 409.0
REGS2_k127_264035_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 310.0
REGS2_k127_264035_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 295.0
REGS2_k127_264035_2 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000003915 55.0
REGS2_k127_2656277_0 N-Acetylmuramoyl-L-alanine amidase K01187 - 3.2.1.20 1.378e-276 866.0
REGS2_k127_2656277_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.171e-275 863.0
REGS2_k127_2656277_2 major facilitator K16211 - - 4.223e-207 656.0
REGS2_k127_2656277_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 380.0
REGS2_k127_2656277_4 Glycogen debranching enzyme, glucanotransferase domain - - - 0.000000000000000000000000000001094 128.0
REGS2_k127_2710294_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 484.0
REGS2_k127_2710294_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 323.0
REGS2_k127_2710294_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
REGS2_k127_2710294_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000001391 169.0
REGS2_k127_2710294_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000004446 122.0
REGS2_k127_2724752_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 352.0
REGS2_k127_2724752_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000001014 226.0
REGS2_k127_2724752_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000006695 107.0
REGS2_k127_2731525_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 529.0
REGS2_k127_2731525_1 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 405.0
REGS2_k127_2731525_2 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000002171 186.0
REGS2_k127_2731525_3 DNA/RNA non-specific endonuclease - - - 0.0000000000000000000000000000000001427 138.0
REGS2_k127_2731525_4 NfeD-like C-terminal, partner-binding - - - 0.00000000000004565 78.0
REGS2_k127_2739332_0 Papain cysteine protease family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 346.0
REGS2_k127_2739332_1 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000002956 245.0
REGS2_k127_2739332_2 GDSL-like Lipase/Acylhydrolase K12686 - - 0.00000000000000000000000000000000000000000000000000000000008353 216.0
REGS2_k127_2739332_3 Transposase K07486 - - 0.0000001454 56.0
REGS2_k127_2785824_0 Dienelactone hydrolase family - - - 2.075e-256 812.0
REGS2_k127_2785824_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.224e-196 637.0
REGS2_k127_2785824_10 - - - - 0.00000000007074 66.0
REGS2_k127_2785824_11 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000004086 57.0
REGS2_k127_2785824_12 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.0001484 47.0
REGS2_k127_2785824_2 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 378.0
REGS2_k127_2785824_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000208 263.0
REGS2_k127_2785824_4 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000001843 239.0
REGS2_k127_2785824_5 Cold shock K03704 - - 0.000000000000000000000000000001052 121.0
REGS2_k127_2785824_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000007599 121.0
REGS2_k127_2785824_7 COG4635 Flavodoxin K00230 - 1.3.5.3 0.0000000000000000000000001996 111.0
REGS2_k127_2785824_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000002341 113.0
REGS2_k127_2785824_9 Alpha/beta hydrolase family - - - 0.000000000000000000005258 106.0
REGS2_k127_2787063_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 496.0
REGS2_k127_2787063_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 411.0
REGS2_k127_2787063_2 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 367.0
REGS2_k127_2787063_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 317.0
REGS2_k127_2787063_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 310.0
REGS2_k127_2787063_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 305.0
REGS2_k127_2787063_6 ABC-type spermidine putrescine transport systems, ATPase components K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002838 269.0
REGS2_k127_2875735_0 peptidase K01415,K07386 - 3.4.24.71 4.946e-228 738.0
REGS2_k127_2875735_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 366.0
REGS2_k127_2875735_2 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003361 263.0
REGS2_k127_2875735_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000174 256.0
REGS2_k127_2875735_4 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000002374 210.0
REGS2_k127_2875735_5 4Fe-4S single cluster domain K07001 - - 0.00000000000000000000000000001168 128.0
REGS2_k127_2875735_6 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000002537 116.0
REGS2_k127_2875735_7 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000005945 80.0
REGS2_k127_2875735_8 23S rRNA-intervening sequence protein - - - 0.00000000006121 68.0
REGS2_k127_2883701_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 6.275e-289 905.0
REGS2_k127_2898818_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.172e-224 712.0
REGS2_k127_2898818_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 7.982e-221 700.0
REGS2_k127_2898818_2 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000009308 139.0
REGS2_k127_2901288_0 Sortilin, neurotensin receptor 3, - - - 0.0 1360.0
REGS2_k127_2901288_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 6.393e-319 1002.0
REGS2_k127_2901288_10 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 411.0
REGS2_k127_2901288_11 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 403.0
REGS2_k127_2901288_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 382.0
REGS2_k127_2901288_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 358.0
REGS2_k127_2901288_14 Zn-dependent protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 351.0
REGS2_k127_2901288_15 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 355.0
REGS2_k127_2901288_16 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 319.0
REGS2_k127_2901288_17 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 310.0
REGS2_k127_2901288_18 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 328.0
REGS2_k127_2901288_19 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 311.0
REGS2_k127_2901288_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.273e-311 982.0
REGS2_k127_2901288_20 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 323.0
REGS2_k127_2901288_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 306.0
REGS2_k127_2901288_22 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006765 287.0
REGS2_k127_2901288_23 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001918 283.0
REGS2_k127_2901288_24 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003489 267.0
REGS2_k127_2901288_25 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003671 244.0
REGS2_k127_2901288_26 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000006821 255.0
REGS2_k127_2901288_27 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000000000001212 240.0
REGS2_k127_2901288_28 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000008502 242.0
REGS2_k127_2901288_29 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
REGS2_k127_2901288_3 lysine biosynthetic process via aminoadipic acid - - - 1.416e-203 665.0
REGS2_k127_2901288_30 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000001553 221.0
REGS2_k127_2901288_31 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000001405 207.0
REGS2_k127_2901288_32 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000003026 201.0
REGS2_k127_2901288_33 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000003252 191.0
REGS2_k127_2901288_34 Tetratricopeptide repeat K08309 - - 0.00000000000000000000000000000000000000004387 174.0
REGS2_k127_2901288_35 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000054 144.0
REGS2_k127_2901288_36 Matrixin - - - 0.0000000000000000000000000000000000002113 151.0
REGS2_k127_2901288_37 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000004862 150.0
REGS2_k127_2901288_38 Rhomboid family - - - 0.000000000000000000000000000000000008316 149.0
REGS2_k127_2901288_39 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000009975 146.0
REGS2_k127_2901288_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 571.0
REGS2_k127_2901288_40 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000001448 145.0
REGS2_k127_2901288_41 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000000000000000001588 140.0
REGS2_k127_2901288_42 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000001404 135.0
REGS2_k127_2901288_43 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000001901 137.0
REGS2_k127_2901288_44 Cold shock K03704 - - 0.0000000000000000000000000000005583 122.0
REGS2_k127_2901288_45 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000009904 116.0
REGS2_k127_2901288_46 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000007214 108.0
REGS2_k127_2901288_47 - - - - 0.000000000000000000000002556 110.0
REGS2_k127_2901288_48 Sporulation related domain - - - 0.00000000000000000002775 101.0
REGS2_k127_2901288_5 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 565.0
REGS2_k127_2901288_50 Protein of unknown function (DUF3307) - - - 0.00000000000000002105 89.0
REGS2_k127_2901288_51 Ribosomal protein L34 K02914 - - 0.0000000000000000357 82.0
REGS2_k127_2901288_52 - - - - 0.00000000000000006376 91.0
REGS2_k127_2901288_53 Thioesterase K07107,K12500 - - 0.0000000000000004039 91.0
REGS2_k127_2901288_54 Protein of unknown function, DUF393 - - - 0.00000000000000304 80.0
REGS2_k127_2901288_55 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000221 79.0
REGS2_k127_2901288_56 SatD family (SatD) - - - 0.00000004412 62.0
REGS2_k127_2901288_57 peptidyl-tyrosine sulfation - - - 0.000007557 59.0
REGS2_k127_2901288_58 TIGRFAM TonB family protein K03832 - - 0.00001856 56.0
REGS2_k127_2901288_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 543.0
REGS2_k127_2901288_7 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 458.0
REGS2_k127_2901288_8 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 441.0
REGS2_k127_2901288_9 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 445.0
REGS2_k127_2902680_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 440.0
REGS2_k127_2902680_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 338.0
REGS2_k127_2902680_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 317.0
REGS2_k127_2902680_3 4Fe-4S single cluster domain K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001482 284.0
REGS2_k127_2902680_4 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000003223 211.0
REGS2_k127_2902680_5 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000000003956 204.0
REGS2_k127_2902680_6 Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.000000000000000000000000000000000000000000000003137 193.0
REGS2_k127_2902680_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000001341 114.0
REGS2_k127_2902680_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000008298 105.0
REGS2_k127_2976981_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 524.0
REGS2_k127_2976981_1 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 340.0
REGS2_k127_2976981_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 294.0
REGS2_k127_2976981_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
REGS2_k127_2976981_4 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002119 211.0
REGS2_k127_2976981_5 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000001009 106.0
REGS2_k127_3016418_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.174e-274 851.0
REGS2_k127_3016418_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 571.0
REGS2_k127_3016418_10 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006184 275.0
REGS2_k127_3016418_11 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000006293 259.0
REGS2_k127_3016418_12 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002826 250.0
REGS2_k127_3016418_13 Sugar nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009689 252.0
REGS2_k127_3016418_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000001426 241.0
REGS2_k127_3016418_15 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000001959 234.0
REGS2_k127_3016418_16 S4 RNA-binding domain K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000001506 233.0
REGS2_k127_3016418_17 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000723 239.0
REGS2_k127_3016418_18 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000008351 215.0
REGS2_k127_3016418_19 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000004218 203.0
REGS2_k127_3016418_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 516.0
REGS2_k127_3016418_20 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000003955 197.0
REGS2_k127_3016418_21 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000552 152.0
REGS2_k127_3016418_22 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000001374 132.0
REGS2_k127_3016418_23 cysteine-type peptidase activity K19224,K21471 - - 0.00000000000000000000000000001367 131.0
REGS2_k127_3016418_24 Oxygen tolerance - - - 0.00000000000000000000000000005397 136.0
REGS2_k127_3016418_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000002289 121.0
REGS2_k127_3016418_26 lyase activity - - - 0.00000000000000000000136 111.0
REGS2_k127_3016418_27 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000004998 95.0
REGS2_k127_3016418_28 Zinc finger domain - - - 0.0000000000000009085 87.0
REGS2_k127_3016418_29 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000001832 76.0
REGS2_k127_3016418_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 524.0
REGS2_k127_3016418_30 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000004449 59.0
REGS2_k127_3016418_31 PBS lyase HEAT-like repeat - - - 0.00000009201 65.0
REGS2_k127_3016418_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 453.0
REGS2_k127_3016418_5 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 438.0
REGS2_k127_3016418_6 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 339.0
REGS2_k127_3016418_7 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 312.0
REGS2_k127_3016418_8 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003432 279.0
REGS2_k127_3016418_9 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
REGS2_k127_3059783_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 514.0
REGS2_k127_3059783_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 321.0
REGS2_k127_3059783_2 BioY family K03523 - - 0.0000000000000000000000001713 116.0
REGS2_k127_307480_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 571.0
REGS2_k127_307480_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 453.0
REGS2_k127_307480_10 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000004999 128.0
REGS2_k127_307480_11 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000006558 134.0
REGS2_k127_307480_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000002 102.0
REGS2_k127_307480_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002591 257.0
REGS2_k127_307480_3 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000004893 227.0
REGS2_k127_307480_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000002674 204.0
REGS2_k127_307480_5 SdpI/YhfL protein family - GO:0008150,GO:0009636,GO:0042221,GO:0050896 - 0.000000000000000000000000000000000000000000000000000001387 198.0
REGS2_k127_307480_6 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000001836 203.0
REGS2_k127_307480_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000003662 158.0
REGS2_k127_307480_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000005344 136.0
REGS2_k127_307480_9 curli production assembly transport component CsgG K04087 - - 0.0000000000000000000000000000000007333 147.0
REGS2_k127_3125590_0 LVIVD repeat - - - 5.588e-227 717.0
REGS2_k127_3162996_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 6.175e-212 666.0
REGS2_k127_3162996_1 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002617 280.0
REGS2_k127_3162996_10 - - - - 0.000000000000000000009628 104.0
REGS2_k127_3162996_11 Putative adhesin - - - 0.0000000000000000000407 102.0
REGS2_k127_3162996_12 Thioredoxin-like - - - 0.0000000000000000002605 102.0
REGS2_k127_3162996_14 - - - - 0.00000000009159 73.0
REGS2_k127_3162996_15 SnoaL-like domain - - - 0.0000002658 62.0
REGS2_k127_3162996_2 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000002701 286.0
REGS2_k127_3162996_3 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
REGS2_k127_3162996_4 PFAM Inosine uridine-preferring nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000001744 212.0
REGS2_k127_3162996_5 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000024 185.0
REGS2_k127_3162996_6 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000005791 176.0
REGS2_k127_3162996_7 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K05556 - - 0.0000000000000000000000000000000000000000000003801 191.0
REGS2_k127_3162996_8 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000003351 147.0
REGS2_k127_3162996_9 NUDIX domain - - - 0.000000000000000000000000000000001635 138.0
REGS2_k127_324395_0 lysine biosynthetic process via aminoadipic acid - - - 2.201e-195 635.0
REGS2_k127_324395_1 Cytosine deaminase-like metal-dependent hydrolase K01487,K12960 - 3.5.4.28,3.5.4.3,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 465.0
REGS2_k127_324395_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00001857 51.0
REGS2_k127_324395_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 443.0
REGS2_k127_324395_3 Cache domain - - - 0.0000000000000000000000000000000007981 148.0
REGS2_k127_324395_4 TonB dependent receptor - - - 0.0000000000000000000000000000000764 141.0
REGS2_k127_324395_5 Cytochrome C biogenesis protein - - - 0.000000000000000000000000005617 118.0
REGS2_k127_324395_6 Cytochrome C biogenesis protein - - - 0.000000000000000000000000007117 119.0
REGS2_k127_324395_7 Protein of unknown function (DUF4876) - - - 0.00000000000000000000008059 112.0
REGS2_k127_324395_8 Protein of unknown function (DUF4876) - - - 0.0000000000000000000702 104.0
REGS2_k127_324395_9 Protein of unknown function (DUF4876) - - - 0.000000000000000001089 100.0
REGS2_k127_3261082_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.675e-275 866.0
REGS2_k127_3261082_1 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 7.719e-262 821.0
REGS2_k127_3261082_10 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 541.0
REGS2_k127_3261082_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 466.0
REGS2_k127_3261082_12 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 433.0
REGS2_k127_3261082_13 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 393.0
REGS2_k127_3261082_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 397.0
REGS2_k127_3261082_15 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 368.0
REGS2_k127_3261082_16 3-methyl-2-oxobutanoate hydroxymethyltransferase activity K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 326.0
REGS2_k127_3261082_17 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 326.0
REGS2_k127_3261082_18 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 319.0
REGS2_k127_3261082_19 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 324.0
REGS2_k127_3261082_2 Carboxyl transferase domain - - - 3.269e-234 734.0
REGS2_k127_3261082_20 Belongs to the peptidase S8 family K01280 - 3.4.14.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 315.0
REGS2_k127_3261082_21 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004852 278.0
REGS2_k127_3261082_22 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007872 271.0
REGS2_k127_3261082_23 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000553 273.0
REGS2_k127_3261082_24 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000287 263.0
REGS2_k127_3261082_25 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005577 257.0
REGS2_k127_3261082_26 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000004087 249.0
REGS2_k127_3261082_27 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000004722 225.0
REGS2_k127_3261082_28 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000002008 224.0
REGS2_k127_3261082_29 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000116 224.0
REGS2_k127_3261082_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.117e-222 705.0
REGS2_k127_3261082_30 Disulphide isomerase - - - 0.0000000000000000000000000000000000000000000000000002046 188.0
REGS2_k127_3261082_31 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000001917 181.0
REGS2_k127_3261082_32 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000002448 181.0
REGS2_k127_3261082_33 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000002468 171.0
REGS2_k127_3261082_34 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.00000000000000000000000000000000000000000005276 173.0
REGS2_k127_3261082_35 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000008043 160.0
REGS2_k127_3261082_36 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000001185 171.0
REGS2_k127_3261082_37 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.000000000000000000000000000000000000000001736 158.0
REGS2_k127_3261082_38 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.000000000000000000000000000000000000000002823 162.0
REGS2_k127_3261082_39 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.0000000000000000000000000000003465 127.0
REGS2_k127_3261082_4 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 4.617e-218 692.0
REGS2_k127_3261082_40 PFAM CBS domain containing protein - - - 0.0000000000000000000000000007978 127.0
REGS2_k127_3261082_41 Cache_2 K03406 - - 0.00000000000000000000000006359 126.0
REGS2_k127_3261082_42 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000005756 98.0
REGS2_k127_3261082_43 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000009842 102.0
REGS2_k127_3261082_44 Transcription factor zinc-finger K09981 - - 0.000000000000000001925 88.0
REGS2_k127_3261082_45 O-methyltransferase activity - - - 0.000000000000000003122 98.0
REGS2_k127_3261082_46 - - - - 0.000000000000000003193 88.0
REGS2_k127_3261082_5 Acyclic terpene utilisation family protein AtuA - - - 2.035e-207 660.0
REGS2_k127_3261082_6 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 581.0
REGS2_k127_3261082_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 572.0
REGS2_k127_3261082_8 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 571.0
REGS2_k127_3261082_9 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 547.0
REGS2_k127_3279200_0 Amidohydrolase family - - - 0.0 1246.0
REGS2_k127_3279200_1 Peptidase family M1 domain - - - 5.137e-235 741.0
REGS2_k127_3279200_10 GIY-YIG catalytic domain K07461 - - 0.000000000000000000005577 106.0
REGS2_k127_3279200_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000003397 63.0
REGS2_k127_3279200_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.865e-207 656.0
REGS2_k127_3279200_3 PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 563.0
REGS2_k127_3279200_4 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 554.0
REGS2_k127_3279200_5 Organic Anion Transporter Polypeptide (OATP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 441.0
REGS2_k127_3279200_6 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 415.0
REGS2_k127_3279200_7 SURF1 family K14998 - - 0.000000000000000000000000000000000000009434 156.0
REGS2_k127_3279200_8 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000003933 146.0
REGS2_k127_3279200_9 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000128 132.0
REGS2_k127_3331994_0 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000111 235.0
REGS2_k127_3331994_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000006791 222.0
REGS2_k127_3331994_2 - - - - 0.0000000000000000000000000000000000000000000000000002054 199.0
REGS2_k127_3331994_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000005347 135.0
REGS2_k127_3331994_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000153 96.0
REGS2_k127_3331994_5 Redoxin K03564 - 1.11.1.15 0.00000000000000005802 83.0
REGS2_k127_3331994_6 Domain of unknown function (DUF309) - - - 0.0002709 52.0
REGS2_k127_3331994_7 Peroxiredoxin K03564 - 1.11.1.15 0.000458 48.0
REGS2_k127_3381801_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1212.0
REGS2_k127_3381801_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 8.125e-230 739.0
REGS2_k127_3381801_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.515e-211 677.0
REGS2_k127_3381801_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 520.0
REGS2_k127_3381801_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000001205 198.0
REGS2_k127_3381801_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000004202 147.0
REGS2_k127_3381801_6 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.00000000000000000000000000000003291 130.0
REGS2_k127_3381801_7 - - - - 0.00000000000000000005184 94.0
REGS2_k127_3381801_8 Heavy-metal-associated domain K07213 - - 0.00000000001731 67.0
REGS2_k127_3469949_0 protein secretion by the type I secretion system K11085 - - 2.919e-213 672.0
REGS2_k127_3469949_1 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 325.0
REGS2_k127_3474961_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 616.0
REGS2_k127_3474961_1 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 432.0
REGS2_k127_3474961_2 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000005601 220.0
REGS2_k127_3474961_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000008412 179.0
REGS2_k127_3474961_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000003506 120.0
REGS2_k127_3474961_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000002862 86.0
REGS2_k127_3481361_0 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 449.0
REGS2_k127_3481361_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000003312 184.0
REGS2_k127_3481361_2 - - - - 0.00000000000000000007143 92.0
REGS2_k127_3481361_3 Haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.00000000006293 64.0
REGS2_k127_3481722_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000531 274.0
REGS2_k127_3481722_1 C4-dicarboxylate transport system K21393 - - 0.0000000000001184 78.0
REGS2_k127_3514886_0 cellulose binding - - - 0.0 1167.0
REGS2_k127_3514886_1 Peptidase family M1 domain - - - 4.355e-251 785.0
REGS2_k127_3514886_10 DinB family - - - 0.0000000000000000001311 99.0
REGS2_k127_3514886_11 Belongs to the ompA family K03640 - - 0.000000000000000006448 89.0
REGS2_k127_3514886_12 - - - - 0.000000003583 63.0
REGS2_k127_3514886_13 SnoaL-like domain - - - 0.00000001067 64.0
REGS2_k127_3514886_2 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 606.0
REGS2_k127_3514886_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 463.0
REGS2_k127_3514886_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 423.0
REGS2_k127_3514886_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 420.0
REGS2_k127_3514886_6 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 380.0
REGS2_k127_3514886_7 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004725 275.0
REGS2_k127_3514886_8 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000004268 205.0
REGS2_k127_3514886_9 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000004806 195.0
REGS2_k127_3519064_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000001312 217.0
REGS2_k127_3519064_1 alpha beta - - - 0.000001863 61.0
REGS2_k127_3519064_2 photosystem II stabilization - - - 0.00003005 57.0
REGS2_k127_353680_0 TonB-dependent receptor - - - 4.203e-229 742.0
REGS2_k127_353680_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 2.335e-197 624.0
REGS2_k127_353680_2 Putative glucoamylase - - - 3.781e-196 624.0
REGS2_k127_353680_3 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 467.0
REGS2_k127_353680_4 ABC-type sugar transport systems, permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 390.0
REGS2_k127_353680_5 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 353.0
REGS2_k127_353680_6 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 348.0
REGS2_k127_3590319_0 Oxidoreductase - - - 3.253e-233 747.0
REGS2_k127_3590319_1 Glycine cleavage T-protein C-terminal barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 488.0
REGS2_k127_3590319_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000002297 156.0
REGS2_k127_3590319_11 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000002019 136.0
REGS2_k127_3590319_12 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000004134 128.0
REGS2_k127_3590319_13 Bacterial protein of unknown function (DUF922) - - - 0.0000000000000000003302 96.0
REGS2_k127_3590319_14 protein conserved in bacteria - - - 0.000001686 51.0
REGS2_k127_3590319_2 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 503.0
REGS2_k127_3590319_3 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 429.0
REGS2_k127_3590319_4 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 332.0
REGS2_k127_3590319_5 protein, Hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002901 263.0
REGS2_k127_3590319_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000008503 202.0
REGS2_k127_3590319_7 - - - - 0.00000000000000000000000000000000000000000000006996 174.0
REGS2_k127_3590319_8 - - - - 0.0000000000000000000000000000000000000000000003237 172.0
REGS2_k127_3590319_9 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000388 157.0
REGS2_k127_3597091_0 Elongation factor G, domain IV K02355 - - 1.037e-263 829.0
REGS2_k127_3597091_1 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 445.0
REGS2_k127_3597091_10 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 323.0
REGS2_k127_3597091_11 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 291.0
REGS2_k127_3597091_12 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005418 263.0
REGS2_k127_3597091_13 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000003251 230.0
REGS2_k127_3597091_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000002449 192.0
REGS2_k127_3597091_15 Histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000008011 178.0
REGS2_k127_3597091_16 ArsC family - - - 0.00000000000000000000000000000000000000001204 156.0
REGS2_k127_3597091_17 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000706 158.0
REGS2_k127_3597091_18 Protein of unknown function DUF116 - - - 0.0000000000000000000000000000000001199 143.0
REGS2_k127_3597091_19 - - - - 0.0000000000000000000000000000000002679 146.0
REGS2_k127_3597091_2 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 445.0
REGS2_k127_3597091_20 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000001271 137.0
REGS2_k127_3597091_21 - - - - 0.0000000000000000000000000002536 123.0
REGS2_k127_3597091_22 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000000000000000005715 91.0
REGS2_k127_3597091_23 haloacid dehalogenase-like hydrolase - - - 0.000000000000001707 79.0
REGS2_k127_3597091_24 Predicted membrane protein (DUF2231) - - - 0.00000001229 67.0
REGS2_k127_3597091_3 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 434.0
REGS2_k127_3597091_4 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 411.0
REGS2_k127_3597091_5 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 376.0
REGS2_k127_3597091_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 363.0
REGS2_k127_3597091_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 370.0
REGS2_k127_3597091_8 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 345.0
REGS2_k127_3597091_9 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 344.0
REGS2_k127_3613175_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 413.0
REGS2_k127_3613175_1 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 366.0
REGS2_k127_3613175_10 Bacterial Ig-like domain 2 - - - 0.00000009933 64.0
REGS2_k127_3613175_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 353.0
REGS2_k127_3613175_3 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 341.0
REGS2_k127_3613175_4 PFAM binding-protein-dependent transport systems inner membrane component K02025,K17242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 313.0
REGS2_k127_3613175_5 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
REGS2_k127_3613175_6 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000001096 246.0
REGS2_k127_3613175_7 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000002305 224.0
REGS2_k127_3613175_8 - - - - 0.0000000000000000000000000002238 128.0
REGS2_k127_3613175_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000002615 63.0
REGS2_k127_3619672_0 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 443.0
REGS2_k127_3619672_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 427.0
REGS2_k127_3619672_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019538,GO:0020037,GO:0030091,GO:0031224,GO:0031226,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000001547 196.0
REGS2_k127_3619672_3 ECF sigma factor K03088 - - 0.0005025 51.0
REGS2_k127_3644089_0 metallopeptidase activity K01637 - 4.1.3.1 0.00000000000001472 87.0
REGS2_k127_3703398_0 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 257.0
REGS2_k127_3703398_1 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000107 252.0
REGS2_k127_3703398_2 Elongation factor G C-terminus K06207 - - 0.0000000000000000000000001856 106.0
REGS2_k127_3703398_3 PFAM S23 ribosomal protein - - - 0.00000000000000000129 93.0
REGS2_k127_3729073_0 oligopeptide transporter, OPT family - - - 4.451e-207 670.0
REGS2_k127_3729073_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 529.0
REGS2_k127_3729073_10 HEAT repeats - - - 0.00000000000000000000000000000000000004505 162.0
REGS2_k127_3729073_11 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000005831 139.0
REGS2_k127_3729073_12 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000001283 115.0
REGS2_k127_3729073_13 phosphorelay sensor kinase activity K16923 - - 0.00000006845 61.0
REGS2_k127_3729073_14 cobalt transport K16785 - - 0.00001107 57.0
REGS2_k127_3729073_2 PFAM peptidase M18 aminopeptidase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 414.0
REGS2_k127_3729073_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 387.0
REGS2_k127_3729073_4 C-terminal AAA-associated domain K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 357.0
REGS2_k127_3729073_5 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 336.0
REGS2_k127_3729073_6 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000008023 255.0
REGS2_k127_3729073_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000005131 188.0
REGS2_k127_3729073_8 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000001339 185.0
REGS2_k127_3729073_9 PFAM ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000372 171.0
REGS2_k127_3731701_0 Dehydrogenase K00117 - 1.1.5.2 1.449e-201 648.0
REGS2_k127_3731701_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 388.0
REGS2_k127_3731701_2 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000185 248.0
REGS2_k127_3731701_3 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000006647 229.0
REGS2_k127_3731701_4 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000472 215.0
REGS2_k127_3731701_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000003836 222.0
REGS2_k127_3731701_6 Thioredoxin-like - - - 0.000000000000000000000000000000000009232 151.0
REGS2_k127_3731701_7 Redoxin - - - 0.0000000000000000000000000008384 115.0
REGS2_k127_3731701_8 Redoxin - - - 0.00000003584 60.0
REGS2_k127_3734186_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 2.346e-222 708.0
REGS2_k127_3734186_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 500.0
REGS2_k127_3734186_2 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 467.0
REGS2_k127_3734186_3 Domain of unknown function(DUF2779) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 434.0
REGS2_k127_3734186_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000005877 179.0
REGS2_k127_3734186_5 EamA-like transporter family - - - 0.000000000000000000000000000000000001604 149.0
REGS2_k127_3734186_6 DinB family - - - 0.000000000000000000000000000000006633 145.0
REGS2_k127_3734186_7 Beta-lactamase - - - 0.0000000000000000000000000000001698 128.0
REGS2_k127_3744852_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.918e-253 796.0
REGS2_k127_3744852_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002219 259.0
REGS2_k127_3744852_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000008001 196.0
REGS2_k127_3744852_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000003456 177.0
REGS2_k127_3744852_4 Flavin reductase like domain - - - 0.00000000000000000002999 98.0
REGS2_k127_3751972_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 532.0
REGS2_k127_3751972_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 512.0
REGS2_k127_3751972_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 339.0
REGS2_k127_3751972_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 344.0
REGS2_k127_3751972_4 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 315.0
REGS2_k127_3751972_5 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000000003027 201.0
REGS2_k127_3751972_6 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000004122 139.0
REGS2_k127_3751972_7 - - - - 0.00000000000000000000000000000001009 148.0
REGS2_k127_3751972_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000199 61.0
REGS2_k127_3770297_0 Pfam:KaiC K08482 - - 7.424e-200 636.0
REGS2_k127_3770297_1 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 451.0
REGS2_k127_3770297_10 response regulator K07782 - - 0.0000000000000000000000000000000000000005794 156.0
REGS2_k127_3770297_11 KaiB K08481 - - 0.000000000000000000000000000000236 140.0
REGS2_k127_3770297_12 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000895 134.0
REGS2_k127_3770297_13 Transglycosylase associated protein - - - 0.00000000000000000000003888 108.0
REGS2_k127_3770297_14 - - - - 0.000000000000000000003781 104.0
REGS2_k127_3770297_15 anaphase-promoting complex binding - - - 0.000000000000002734 89.0
REGS2_k127_3770297_16 domain protein - - - 0.000000000000002986 87.0
REGS2_k127_3770297_17 - - - - 0.0000000002287 63.0
REGS2_k127_3770297_18 Belongs to the UPF0337 (CsbD) family - - - 0.00000000291 61.0
REGS2_k127_3770297_19 BON domain - - - 0.0000001767 62.0
REGS2_k127_3770297_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 387.0
REGS2_k127_3770297_20 S-layer homology domain - - - 0.00000115 60.0
REGS2_k127_3770297_22 - - - - 0.00002604 56.0
REGS2_k127_3770297_3 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
REGS2_k127_3770297_4 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000002453 250.0
REGS2_k127_3770297_5 Protein of unknown function (DUF3494) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000002474 220.0
REGS2_k127_3770297_6 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000006225 197.0
REGS2_k127_3770297_7 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000002786 193.0
REGS2_k127_3770297_8 response regulator K07782 - - 0.000000000000000000000000000000000000000000000003883 181.0
REGS2_k127_3770297_9 response regulator K07782 - - 0.00000000000000000000000000000000000000000000001092 180.0
REGS2_k127_3855847_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 554.0
REGS2_k127_3855847_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 436.0
REGS2_k127_3855847_10 - - - - 0.0000000000000000000000000000000000000000000000000000000002705 220.0
REGS2_k127_3855847_11 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000007457 194.0
REGS2_k127_3855847_12 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000003702 162.0
REGS2_k127_3855847_13 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000000000000000000003231 137.0
REGS2_k127_3855847_14 - - - - 0.0000000000000000000000000004384 130.0
REGS2_k127_3855847_15 - - - - 0.0000000000000000000000276 111.0
REGS2_k127_3855847_16 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000004364 89.0
REGS2_k127_3855847_18 - - - - 0.000001378 59.0
REGS2_k127_3855847_19 - - - - 0.00000513 57.0
REGS2_k127_3855847_2 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 433.0
REGS2_k127_3855847_3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 397.0
REGS2_k127_3855847_4 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 370.0
REGS2_k127_3855847_5 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 356.0
REGS2_k127_3855847_6 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 337.0
REGS2_k127_3855847_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 276.0
REGS2_k127_3855847_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
REGS2_k127_3855847_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003124 285.0
REGS2_k127_3887460_0 RNA polymerase binding - - - 1.033e-305 1026.0
REGS2_k127_3887460_1 Prolyl oligopeptidase family K01303 - 3.4.19.1 1.77e-259 818.0
REGS2_k127_3887460_10 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 356.0
REGS2_k127_3887460_11 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 346.0
REGS2_k127_3887460_12 aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 341.0
REGS2_k127_3887460_13 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 323.0
REGS2_k127_3887460_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000562 280.0
REGS2_k127_3887460_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005297 228.0
REGS2_k127_3887460_16 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000006104 221.0
REGS2_k127_3887460_17 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000325 198.0
REGS2_k127_3887460_18 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000005342 195.0
REGS2_k127_3887460_19 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000003614 166.0
REGS2_k127_3887460_2 Bacterial regulatory protein, Fis family - - - 3.079e-201 642.0
REGS2_k127_3887460_20 Transcriptional - - - 0.000000000000000000000000000000002189 133.0
REGS2_k127_3887460_21 positive regulation of proteasomal protein catabolic process - - - 0.0000000000000000000000000000004484 139.0
REGS2_k127_3887460_22 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000006021 111.0
REGS2_k127_3887460_23 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000006071 108.0
REGS2_k127_3887460_24 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000001142 107.0
REGS2_k127_3887460_25 Domain of unknown function (DUF1736) - - - 0.000000000000000000000178 113.0
REGS2_k127_3887460_26 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.000000000000273 77.0
REGS2_k127_3887460_27 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001572 57.0
REGS2_k127_3887460_28 Peptidase M56 - - - 0.00002496 49.0
REGS2_k127_3887460_29 pilus assembly protein PilW K02672 - - 0.00006463 54.0
REGS2_k127_3887460_3 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 620.0
REGS2_k127_3887460_30 Prokaryotic N-terminal methylation motif K02655 - - 0.0001796 50.0
REGS2_k127_3887460_4 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 625.0
REGS2_k127_3887460_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 584.0
REGS2_k127_3887460_6 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 541.0
REGS2_k127_3887460_7 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 493.0
REGS2_k127_3887460_8 PAS domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 424.0
REGS2_k127_3887460_9 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 362.0
REGS2_k127_3890234_0 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 532.0
REGS2_k127_3890234_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 374.0
REGS2_k127_3890234_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000008126 151.0
REGS2_k127_3890234_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000002928 145.0
REGS2_k127_38957_0 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000001048 169.0
REGS2_k127_38957_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000004317 111.0
REGS2_k127_38957_2 Multicopper oxidase K22349 - 1.16.3.3 0.00000000257 61.0
REGS2_k127_38957_3 Putative zinc-finger - - - 0.00004369 55.0
REGS2_k127_3926156_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 550.0
REGS2_k127_3926156_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 497.0
REGS2_k127_3926156_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002897 272.0
REGS2_k127_3926156_11 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003387 275.0
REGS2_k127_3926156_12 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000003881 252.0
REGS2_k127_3926156_13 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000007738 125.0
REGS2_k127_3926156_14 Cell division protein FtsQ K03589 - - 0.000000000000000000001067 109.0
REGS2_k127_3926156_15 Tetratricopeptide repeat - - - 0.0000000000000001625 94.0
REGS2_k127_3926156_17 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00001148 48.0
REGS2_k127_3926156_19 - - - - 0.0009561 48.0
REGS2_k127_3926156_2 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 456.0
REGS2_k127_3926156_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 437.0
REGS2_k127_3926156_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 445.0
REGS2_k127_3926156_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 439.0
REGS2_k127_3926156_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 425.0
REGS2_k127_3926156_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 333.0
REGS2_k127_3926156_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 312.0
REGS2_k127_3926156_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000392 275.0
REGS2_k127_3938196_0 Penicillin amidase - - - 2.313e-316 987.0
REGS2_k127_3938196_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000001066 146.0
REGS2_k127_3962862_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000001338 123.0
REGS2_k127_3962862_1 Aminotransferase class I and II K10907 - - 0.00000000000000138 78.0
REGS2_k127_4018145_0 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 290.0
REGS2_k127_4018145_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000004846 131.0
REGS2_k127_4018145_2 - - - - 0.0003155 53.0
REGS2_k127_4139974_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000174 282.0
REGS2_k127_4139974_1 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000001711 262.0
REGS2_k127_4145963_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.771e-199 625.0
REGS2_k127_4145963_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 304.0
REGS2_k127_4145963_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000247 135.0
REGS2_k127_4250398_0 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 505.0
REGS2_k127_4250398_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 349.0
REGS2_k127_4250398_10 PFAM blue (type 1) copper domain protein - - - 0.0000001495 63.0
REGS2_k127_4250398_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000001654 197.0
REGS2_k127_4250398_3 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000001049 198.0
REGS2_k127_4250398_4 PFAM Amino acid K20265 - - 0.0000000000000000000000000000000000000000000002179 176.0
REGS2_k127_4250398_5 PAP2 superfamily - - - 0.00000000000000000000000007234 121.0
REGS2_k127_4250398_6 Acid phosphatase homologues - - - 0.00000000000004929 82.0
REGS2_k127_4250398_7 PAP2 superfamily - - - 0.0000000000001987 81.0
REGS2_k127_4250398_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000214 66.0
REGS2_k127_4250398_9 Alpha beta hydrolase - - - 0.000000005381 67.0
REGS2_k127_4271457_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 2.789e-295 934.0
REGS2_k127_4271457_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 582.0
REGS2_k127_4271457_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 363.0
REGS2_k127_4331687_0 cellulose binding - - - 1.143e-212 692.0
REGS2_k127_4331687_1 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 370.0
REGS2_k127_4331687_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 341.0
REGS2_k127_4331687_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 323.0
REGS2_k127_4331687_4 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001144 256.0
REGS2_k127_4331687_5 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
REGS2_k127_4331687_6 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000001384 232.0
REGS2_k127_4331687_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000002557 227.0
REGS2_k127_4331687_8 nuclear chromosome segregation - - - 0.0000000000000000000000000000001208 137.0
REGS2_k127_4339684_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1065.0
REGS2_k127_4339684_1 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 406.0
REGS2_k127_4339684_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 425.0
REGS2_k127_4339684_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
REGS2_k127_4339684_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000812 162.0
REGS2_k127_4339684_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.0000000000000000000000000000004797 131.0
REGS2_k127_4339684_6 Cache_2 K03406 - - 0.00000000000000000000000000000573 138.0
REGS2_k127_4339684_7 Acetyltransferase (GNAT) domain K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000003697 120.0
REGS2_k127_4339684_8 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000008015 68.0
REGS2_k127_4370034_0 Required for chromosome condensation and partitioning K03529 - - 1.237e-275 889.0
REGS2_k127_4370034_1 Aldehyde dehydrogenase family K22187 - - 4.453e-253 787.0
REGS2_k127_4370034_10 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 450.0
REGS2_k127_4370034_11 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 464.0
REGS2_k127_4370034_12 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 357.0
REGS2_k127_4370034_13 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000009581 259.0
REGS2_k127_4370034_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
REGS2_k127_4370034_15 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000002421 250.0
REGS2_k127_4370034_16 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
REGS2_k127_4370034_17 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000002922 218.0
REGS2_k127_4370034_18 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000007502 235.0
REGS2_k127_4370034_19 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000003349 240.0
REGS2_k127_4370034_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 605.0
REGS2_k127_4370034_20 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000001098 216.0
REGS2_k127_4370034_21 - - - - 0.000000000000000000000000000000000000000000000002828 199.0
REGS2_k127_4370034_22 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000001482 173.0
REGS2_k127_4370034_23 PFAM NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000000000000000000007682 164.0
REGS2_k127_4370034_24 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000003945 154.0
REGS2_k127_4370034_25 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000007563 146.0
REGS2_k127_4370034_26 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000007712 143.0
REGS2_k127_4370034_27 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000382 133.0
REGS2_k127_4370034_28 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000002431 129.0
REGS2_k127_4370034_29 membrane transporter protein K07090 - - 0.00000000000000000000000000005759 123.0
REGS2_k127_4370034_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 577.0
REGS2_k127_4370034_30 50S ribosomal protein L31 K02909 - - 0.0000000000000000000001575 101.0
REGS2_k127_4370034_31 - - - - 0.000000000000000000000741 108.0
REGS2_k127_4370034_32 Sporulation related domain - - - 0.000000000000000000007709 106.0
REGS2_k127_4370034_33 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000002238 87.0
REGS2_k127_4370034_34 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000001741 86.0
REGS2_k127_4370034_36 - - - - 0.0000004217 59.0
REGS2_k127_4370034_37 Sporulation related domain - - - 0.00002578 47.0
REGS2_k127_4370034_38 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0003382 52.0
REGS2_k127_4370034_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 546.0
REGS2_k127_4370034_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 547.0
REGS2_k127_4370034_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 505.0
REGS2_k127_4370034_7 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 489.0
REGS2_k127_4370034_8 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 478.0
REGS2_k127_4370034_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 454.0
REGS2_k127_4377385_0 KaiC K08482 - - 2.21e-204 650.0
REGS2_k127_4377385_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 490.0
REGS2_k127_4377385_11 - - - - 0.00000000000000002355 84.0
REGS2_k127_4377385_12 PspC domain protein - - - 0.0000000000000002978 81.0
REGS2_k127_4377385_14 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000003941 78.0
REGS2_k127_4377385_15 - - - - 0.0000000000008271 77.0
REGS2_k127_4377385_18 SnoaL-like domain - - - 0.0000001992 60.0
REGS2_k127_4377385_19 - - - - 0.000004502 56.0
REGS2_k127_4377385_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 415.0
REGS2_k127_4377385_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 355.0
REGS2_k127_4377385_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 368.0
REGS2_k127_4377385_5 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000009981 186.0
REGS2_k127_4377385_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000002072 150.0
REGS2_k127_4377385_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000009511 155.0
REGS2_k127_4377385_9 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000002947 126.0
REGS2_k127_4378589_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.174e-301 938.0
REGS2_k127_4378589_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 9.586e-277 872.0
REGS2_k127_4378589_10 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 437.0
REGS2_k127_4378589_11 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 442.0
REGS2_k127_4378589_12 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 439.0
REGS2_k127_4378589_13 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 438.0
REGS2_k127_4378589_14 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 406.0
REGS2_k127_4378589_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 389.0
REGS2_k127_4378589_16 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 387.0
REGS2_k127_4378589_17 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 365.0
REGS2_k127_4378589_18 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 330.0
REGS2_k127_4378589_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 313.0
REGS2_k127_4378589_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.113e-262 812.0
REGS2_k127_4378589_20 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001342 291.0
REGS2_k127_4378589_21 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005054 296.0
REGS2_k127_4378589_22 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003957 272.0
REGS2_k127_4378589_23 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004022 263.0
REGS2_k127_4378589_24 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
REGS2_k127_4378589_25 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000004806 237.0
REGS2_k127_4378589_26 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000001309 224.0
REGS2_k127_4378589_27 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000009608 230.0
REGS2_k127_4378589_28 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000001485 221.0
REGS2_k127_4378589_29 - - - - 0.000000000000000000000000000000000000000000000000000000000006235 214.0
REGS2_k127_4378589_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.191e-236 740.0
REGS2_k127_4378589_30 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000648 219.0
REGS2_k127_4378589_31 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000006704 199.0
REGS2_k127_4378589_32 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000001479 201.0
REGS2_k127_4378589_33 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000007504 191.0
REGS2_k127_4378589_34 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000007344 191.0
REGS2_k127_4378589_35 Cupin domain - - - 0.0000000000000000000000000000000000000000000000278 183.0
REGS2_k127_4378589_36 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000001489 173.0
REGS2_k127_4378589_37 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000002032 159.0
REGS2_k127_4378589_38 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000001364 142.0
REGS2_k127_4378589_39 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000002219 122.0
REGS2_k127_4378589_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.39e-200 642.0
REGS2_k127_4378589_40 Polysaccharide deacetylase - - - 0.000000000000000000000000000109 126.0
REGS2_k127_4378589_41 Biotin-requiring enzyme - - - 0.00000000000000000000000004852 118.0
REGS2_k127_4378589_42 rod shape-determining protein MreD K03571 - - 0.000000000000000000000001879 113.0
REGS2_k127_4378589_45 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000002064 58.0
REGS2_k127_4378589_5 Hsp70 protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 593.0
REGS2_k127_4378589_6 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 574.0
REGS2_k127_4378589_7 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 577.0
REGS2_k127_4378589_8 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 534.0
REGS2_k127_4378589_9 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 456.0
REGS2_k127_4396753_0 Prolyl oligopeptidase family - - - 1.685e-206 657.0
REGS2_k127_4396753_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
REGS2_k127_4442312_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 3.266e-231 724.0
REGS2_k127_4442312_1 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 605.0
REGS2_k127_4442312_10 6-phosphogluconolactonase activity - - - 0.0001298 51.0
REGS2_k127_4442312_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 359.0
REGS2_k127_4442312_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 360.0
REGS2_k127_4442312_4 response to abiotic stimulus - - - 0.00000000000000000000000000000000000000000000000003642 186.0
REGS2_k127_4442312_5 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000008534 150.0
REGS2_k127_4442312_6 - - - - 0.00000000000000000007487 98.0
REGS2_k127_4442312_7 COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 - - 0.00000000000000001879 85.0
REGS2_k127_4442312_8 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000002573 90.0
REGS2_k127_4442312_9 Tfp pilus assembly protein FimT - - - 0.000002071 59.0
REGS2_k127_4534266_0 glycosyl transferase group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000001601 206.0
REGS2_k127_4534266_1 - - - - 0.0000000000000000000000000000000000000001005 154.0
REGS2_k127_4534266_2 - - - - 0.00000000000000000000000000199 116.0
REGS2_k127_4534266_3 PFAM Glycosyl transferase, group 1 - - - 0.0000004876 61.0
REGS2_k127_4534266_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0001268 44.0
REGS2_k127_453801_0 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 454.0
REGS2_k127_453801_1 Sodium:dicarboxylate symporter family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 389.0
REGS2_k127_453801_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 301.0
REGS2_k127_453801_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000001368 131.0
REGS2_k127_453801_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000368 102.0
REGS2_k127_453801_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000005552 83.0
REGS2_k127_453801_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000001201 72.0
REGS2_k127_453801_7 23S rRNA-intervening sequence protein - - - 0.000002251 55.0
REGS2_k127_4544550_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 389.0
REGS2_k127_4544550_1 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 330.0
REGS2_k127_4544550_2 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000003546 157.0
REGS2_k127_4544550_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000005068 126.0
REGS2_k127_4544550_4 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000001411 124.0
REGS2_k127_4553509_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 4.981e-205 675.0
REGS2_k127_4553509_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 589.0
REGS2_k127_4553509_2 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 484.0
REGS2_k127_4553509_3 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 335.0
REGS2_k127_4553509_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 300.0
REGS2_k127_4553509_5 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001618 285.0
REGS2_k127_4553509_6 competence protein COMEC K02237,K02238 - - 0.000000000000000000000000000000000000002591 158.0
REGS2_k127_4553509_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000133 81.0
REGS2_k127_4554155_0 HELICc2 K03722 - 3.6.4.12 8.131e-277 875.0
REGS2_k127_4554155_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 550.0
REGS2_k127_4554155_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
REGS2_k127_4554155_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 351.0
REGS2_k127_4554155_4 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 336.0
REGS2_k127_4554155_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000001665 171.0
REGS2_k127_4554155_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.0000000000000000000000000000000000000000008114 178.0
REGS2_k127_4554155_7 Endoribonuclease L-PSP - - - 0.0000000000000007425 87.0
REGS2_k127_4554155_8 - - - - 0.00000004229 64.0
REGS2_k127_4571196_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 300.0
REGS2_k127_4571196_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004022 276.0
REGS2_k127_4571196_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003509 256.0
REGS2_k127_4571196_3 DNA polymerase involved in DNA repair K14161 - - 0.000004518 54.0
REGS2_k127_4571196_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0001073 46.0
REGS2_k127_4637571_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 388.0
REGS2_k127_4637571_1 Cytochrome c K00406,K16255 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 337.0
REGS2_k127_4637571_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
REGS2_k127_4637571_3 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000004353 236.0
REGS2_k127_4637571_4 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000001477 224.0
REGS2_k127_4653475_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
REGS2_k127_4653475_1 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000001832 207.0
REGS2_k127_4672515_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 239.0
REGS2_k127_4672515_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006143 240.0
REGS2_k127_4741919_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.762e-229 747.0
REGS2_k127_4741919_1 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 325.0
REGS2_k127_4741919_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 302.0
REGS2_k127_4741919_3 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000538 285.0
REGS2_k127_4741919_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000002385 222.0
REGS2_k127_4741919_5 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000004074 216.0
REGS2_k127_4741919_6 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.0000000000000000000000000000000000000000002617 181.0
REGS2_k127_4741919_7 COG1253 Hemolysins and related - - - 0.000000000000000000000000000000000000003273 152.0
REGS2_k127_4741919_8 23S rRNA-intervening sequence protein - - - 0.00000000000000000521 91.0
REGS2_k127_4741919_9 cell adhesion involved in biofilm formation - - - 0.000000003199 69.0
REGS2_k127_4810825_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 608.0
REGS2_k127_4810825_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000002766 153.0
REGS2_k127_4872158_0 beta-N-acetylhexosaminidase activity - - - 2.981e-224 714.0
REGS2_k127_4872158_1 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 375.0
REGS2_k127_4872158_2 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 344.0
REGS2_k127_4872158_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 325.0
REGS2_k127_4872158_4 LacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 302.0
REGS2_k127_4872158_5 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000003482 128.0
REGS2_k127_4872158_6 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.00000000000000000000000002407 115.0
REGS2_k127_4872158_7 cytochrome K05889,K17222 - 1.1.2.6 0.0002104 48.0
REGS2_k127_4872158_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.0004546 53.0
REGS2_k127_4875984_0 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003748 288.0
REGS2_k127_4875984_1 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000001247 117.0
REGS2_k127_4875984_2 cheY-homologous receiver domain - - - 0.000000000000000005547 91.0
REGS2_k127_4875984_3 Sugar nucleotidyl transferase - - - 0.00001213 51.0
REGS2_k127_4911051_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 425.0
REGS2_k127_4911051_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 417.0
REGS2_k127_4911051_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 389.0
REGS2_k127_4911051_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 337.0
REGS2_k127_4911051_4 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000004241 154.0
REGS2_k127_4911051_5 HIT domain K02503 - - 0.00000000000000000000000000000000002896 150.0
REGS2_k127_4919950_0 secondary active sulfate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 455.0
REGS2_k127_4926313_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003885 271.0
REGS2_k127_4926313_1 pilus organization K07346 - - 0.000000000000000000000000000000000000000000000000002031 192.0
REGS2_k127_4926313_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000006085 102.0
REGS2_k127_4936244_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 637.0
REGS2_k127_4936244_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 529.0
REGS2_k127_4936244_2 Glycogen debranching enzyme, glucanotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 309.0
REGS2_k127_4936244_3 TonB dependent receptor K21573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002024 253.0
REGS2_k127_4936244_4 Putative esterase - - - 0.0000000000000000000000000000000000000007524 171.0
REGS2_k127_50094_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000006748 166.0
REGS2_k127_50094_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000005318 156.0
REGS2_k127_50094_2 23S rRNA-intervening sequence protein - - - 0.000000001107 65.0
REGS2_k127_505575_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1598.0
REGS2_k127_505575_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 488.0
REGS2_k127_505575_10 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000006029 140.0
REGS2_k127_505575_11 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000003616 97.0
REGS2_k127_505575_12 Ribosomal protein L36 K02919 - - 0.000000000000004291 76.0
REGS2_k127_505575_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 451.0
REGS2_k127_505575_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 308.0
REGS2_k127_505575_4 O-acyltransferase activity K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000257 271.0
REGS2_k127_505575_5 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000007118 246.0
REGS2_k127_505575_6 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000005213 231.0
REGS2_k127_505575_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000004561 209.0
REGS2_k127_505575_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000001337 193.0
REGS2_k127_505575_9 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000002083 165.0
REGS2_k127_5170502_0 DEAD/H associated K03724 - - 4.503e-260 812.0
REGS2_k127_5176324_0 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 559.0
REGS2_k127_5176324_1 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 385.0
REGS2_k127_5176324_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 313.0
REGS2_k127_5176324_3 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000001616 175.0
REGS2_k127_5176324_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000008022 106.0
REGS2_k127_5176324_5 TM2 domain - - - 0.000000000000000003202 91.0
REGS2_k127_5176324_6 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000003262 81.0
REGS2_k127_5176324_7 Peptidase family M1 domain - - - 0.0000000000000005078 79.0
REGS2_k127_5192659_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1056.0
REGS2_k127_5192659_1 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 291.0
REGS2_k127_5192659_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000001101 195.0
REGS2_k127_5192659_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000002188 166.0
REGS2_k127_520217_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 7.613e-204 645.0
REGS2_k127_520217_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 551.0
REGS2_k127_520217_10 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009956 283.0
REGS2_k127_520217_11 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
REGS2_k127_520217_12 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003191 244.0
REGS2_k127_520217_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
REGS2_k127_520217_14 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000001015 258.0
REGS2_k127_520217_15 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
REGS2_k127_520217_16 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003244 245.0
REGS2_k127_520217_17 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000008944 234.0
REGS2_k127_520217_18 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000001685 232.0
REGS2_k127_520217_19 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000557 212.0
REGS2_k127_520217_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 524.0
REGS2_k127_520217_20 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000021 198.0
REGS2_k127_520217_21 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000001911 183.0
REGS2_k127_520217_22 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000001282 185.0
REGS2_k127_520217_23 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002744 160.0
REGS2_k127_520217_24 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000003909 155.0
REGS2_k127_520217_25 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002771 145.0
REGS2_k127_520217_26 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000002473 141.0
REGS2_k127_520217_27 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000001314 138.0
REGS2_k127_520217_28 MgtC family K07507 - - 0.000000000000000000000000000000007717 145.0
REGS2_k127_520217_29 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000001245 126.0
REGS2_k127_520217_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 509.0
REGS2_k127_520217_30 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000004338 106.0
REGS2_k127_520217_31 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000001078 102.0
REGS2_k127_520217_32 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000004162 96.0
REGS2_k127_520217_33 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000001299 83.0
REGS2_k127_520217_34 Zincin-like metallopeptidase - - - 0.000000000000003184 84.0
REGS2_k127_520217_35 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000003397 75.0
REGS2_k127_520217_36 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000002709 57.0
REGS2_k127_520217_37 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000421 55.0
REGS2_k127_520217_38 Peptidase family M28 - - - 0.0001384 54.0
REGS2_k127_520217_4 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 451.0
REGS2_k127_520217_5 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 424.0
REGS2_k127_520217_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 421.0
REGS2_k127_520217_7 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 436.0
REGS2_k127_520217_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 354.0
REGS2_k127_520217_9 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 331.0
REGS2_k127_5226126_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.669e-245 773.0
REGS2_k127_5226126_1 Endoribonuclease that initiates mRNA decay K18682 - - 2.371e-196 624.0
REGS2_k127_5226126_10 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 267.0
REGS2_k127_5226126_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000003478 265.0
REGS2_k127_5226126_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000001858 235.0
REGS2_k127_5226126_13 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000005745 194.0
REGS2_k127_5226126_14 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000005136 160.0
REGS2_k127_5226126_15 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000001827 102.0
REGS2_k127_5226126_16 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000002012 87.0
REGS2_k127_5226126_17 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000007118 67.0
REGS2_k127_5226126_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0005392 52.0
REGS2_k127_5226126_2 B3/4 domain K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 625.0
REGS2_k127_5226126_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 477.0
REGS2_k127_5226126_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 398.0
REGS2_k127_5226126_5 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 388.0
REGS2_k127_5226126_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 342.0
REGS2_k127_5226126_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 311.0
REGS2_k127_5226126_8 Arginine deiminase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002326 285.0
REGS2_k127_5226126_9 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005983 286.0
REGS2_k127_5226762_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2248.0
REGS2_k127_5226762_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 287.0
REGS2_k127_5226762_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001011 241.0
REGS2_k127_5226762_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000002654 225.0
REGS2_k127_5226762_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000001143 121.0
REGS2_k127_5226762_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000257 107.0
REGS2_k127_5229620_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1111.0
REGS2_k127_5229620_1 Glycogen debranching enzyme - - - 4.494e-263 837.0
REGS2_k127_5229620_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 304.0
REGS2_k127_5229620_11 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004738 253.0
REGS2_k127_5229620_12 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003283 257.0
REGS2_k127_5229620_13 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
REGS2_k127_5229620_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000001193 194.0
REGS2_k127_5229620_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000007758 197.0
REGS2_k127_5229620_16 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000005114 192.0
REGS2_k127_5229620_17 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000001732 180.0
REGS2_k127_5229620_18 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000001692 184.0
REGS2_k127_5229620_19 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000001855 185.0
REGS2_k127_5229620_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 534.0
REGS2_k127_5229620_20 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000002045 173.0
REGS2_k127_5229620_21 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000009012 149.0
REGS2_k127_5229620_22 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000009514 145.0
REGS2_k127_5229620_23 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000008432 108.0
REGS2_k127_5229620_24 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000003936 113.0
REGS2_k127_5229620_25 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.000000000000000005049 91.0
REGS2_k127_5229620_26 Transcriptional regulator K22106 - - 0.000000000000006327 82.0
REGS2_k127_5229620_27 Surface antigen - - - 0.000000000007199 78.0
REGS2_k127_5229620_28 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000001085 65.0
REGS2_k127_5229620_29 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.0005761 53.0
REGS2_k127_5229620_3 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 500.0
REGS2_k127_5229620_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 451.0
REGS2_k127_5229620_5 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 435.0
REGS2_k127_5229620_6 Asparaginase K01444 - 3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 388.0
REGS2_k127_5229620_7 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 379.0
REGS2_k127_5229620_8 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 359.0
REGS2_k127_5229620_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 340.0
REGS2_k127_5253064_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 545.0
REGS2_k127_5253064_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000001125 175.0
REGS2_k127_5253064_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000006701 173.0
REGS2_k127_5253064_3 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000002591 153.0
REGS2_k127_5253064_4 - - - - 0.000000000000000000000000000003874 123.0
REGS2_k127_5253064_5 - - - - 0.000000000000000000000000001017 113.0
REGS2_k127_5253064_6 - - - - 0.0000000000003255 69.0
REGS2_k127_5253064_7 - - - - 0.000000000005866 69.0
REGS2_k127_5253064_8 - - - - 0.00000000003044 72.0
REGS2_k127_5253064_9 COG NOG14552 non supervised orthologous group - - - 0.0000000001903 61.0
REGS2_k127_5274040_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000001248 173.0
REGS2_k127_5274040_1 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000008183 163.0
REGS2_k127_5274040_2 Putative serine dehydratase domain - - - 0.00000000000000000000000000009296 125.0
REGS2_k127_5274040_3 PFAM Membrane protein of K08972 - - 0.00000000000000000000003298 108.0
REGS2_k127_5292015_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1100.0
REGS2_k127_5292015_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.897e-235 737.0
REGS2_k127_5292015_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001129 270.0
REGS2_k127_5292015_11 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000001867 254.0
REGS2_k127_5292015_12 CheC-like family K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004144 245.0
REGS2_k127_5292015_13 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000005643 258.0
REGS2_k127_5292015_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000001061 213.0
REGS2_k127_5292015_15 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000002086 211.0
REGS2_k127_5292015_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000002815 191.0
REGS2_k127_5292015_17 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000282 158.0
REGS2_k127_5292015_18 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000002096 138.0
REGS2_k127_5292015_19 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000005222 133.0
REGS2_k127_5292015_2 P2 response regulator binding domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 490.0
REGS2_k127_5292015_20 Cell division initiation protein K04074 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000161 79.0
REGS2_k127_5292015_21 Two component signalling adaptor domain K03408 - - 0.000000005027 64.0
REGS2_k127_5292015_23 PFAM Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.0000004231 62.0
REGS2_k127_5292015_24 Roadblock/LC7 domain - - - 0.000003435 58.0
REGS2_k127_5292015_25 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.00002976 56.0
REGS2_k127_5292015_3 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 473.0
REGS2_k127_5292015_4 Bacterial dnaA protein K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 443.0
REGS2_k127_5292015_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 446.0
REGS2_k127_5292015_6 Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 289.0
REGS2_k127_5292015_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 294.0
REGS2_k127_5292015_8 secondary active sulfate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 309.0
REGS2_k127_5292015_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000001768 280.0
REGS2_k127_5334473_0 Carbohydrate family 9 binding domain-like - - - 7.184e-290 913.0
REGS2_k127_5334473_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 3.704e-261 823.0
REGS2_k127_5334473_10 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 460.0
REGS2_k127_5334473_11 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 451.0
REGS2_k127_5334473_12 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 477.0
REGS2_k127_5334473_13 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 423.0
REGS2_k127_5334473_14 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 396.0
REGS2_k127_5334473_15 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 397.0
REGS2_k127_5334473_16 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 416.0
REGS2_k127_5334473_17 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 372.0
REGS2_k127_5334473_18 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 363.0
REGS2_k127_5334473_19 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 348.0
REGS2_k127_5334473_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.345e-242 755.0
REGS2_k127_5334473_20 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 335.0
REGS2_k127_5334473_21 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 325.0
REGS2_k127_5334473_22 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 319.0
REGS2_k127_5334473_23 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 295.0
REGS2_k127_5334473_24 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004838 275.0
REGS2_k127_5334473_25 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004161 284.0
REGS2_k127_5334473_26 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001354 272.0
REGS2_k127_5334473_27 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 261.0
REGS2_k127_5334473_28 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003203 267.0
REGS2_k127_5334473_29 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009058 257.0
REGS2_k127_5334473_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 7.865e-231 730.0
REGS2_k127_5334473_30 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007046 259.0
REGS2_k127_5334473_31 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002382 235.0
REGS2_k127_5334473_32 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000003198 228.0
REGS2_k127_5334473_33 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000006724 239.0
REGS2_k127_5334473_34 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000006083 224.0
REGS2_k127_5334473_35 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000008178 229.0
REGS2_k127_5334473_36 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000000000004553 215.0
REGS2_k127_5334473_37 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000006023 203.0
REGS2_k127_5334473_38 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000006023 187.0
REGS2_k127_5334473_39 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000001527 190.0
REGS2_k127_5334473_4 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 8.607e-204 651.0
REGS2_k127_5334473_40 - - - - 0.00000000000000000000000000000000000000001746 172.0
REGS2_k127_5334473_41 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000004646 151.0
REGS2_k127_5334473_42 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001007 153.0
REGS2_k127_5334473_43 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.00000000000000000000000000000000000003304 156.0
REGS2_k127_5334473_44 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000007524 152.0
REGS2_k127_5334473_45 PFAM Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000005447 142.0
REGS2_k127_5334473_46 diguanylate cyclase - - - 0.00000000000000000000000000000000003156 154.0
REGS2_k127_5334473_47 4 iron, 4 sulfur cluster binding K02572,K02573 - - 0.0000000000000000000000000000000006926 149.0
REGS2_k127_5334473_48 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000008357 137.0
REGS2_k127_5334473_49 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000002402 138.0
REGS2_k127_5334473_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 8.508e-203 644.0
REGS2_k127_5334473_50 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000001745 125.0
REGS2_k127_5334473_51 LytTr DNA-binding domain - - - 0.000000000000000000000000006268 124.0
REGS2_k127_5334473_52 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000005098 112.0
REGS2_k127_5334473_53 - - - - 0.000000000000000000000002583 116.0
REGS2_k127_5334473_54 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000003649 96.0
REGS2_k127_5334473_55 ATP synthesis coupled proton transport K02109 - - 0.0000000000000000007544 97.0
REGS2_k127_5334473_56 - - - - 0.0000000000000000116 92.0
REGS2_k127_5334473_57 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000009872 80.0
REGS2_k127_5334473_58 - - - - 0.0000002278 55.0
REGS2_k127_5334473_59 Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME) K16369 GO:0003674,GO:0003824,GO:0004608,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006629,GO:0006644,GO:0006650,GO:0006656,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008610,GO:0008654,GO:0008757,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016740,GO:0016741,GO:0019637,GO:0031224,GO:0032259,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045017,GO:0046470,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.1.1.17 0.000002676 58.0
REGS2_k127_5334473_6 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 3.854e-199 625.0
REGS2_k127_5334473_60 chaperone-mediated protein folding - - - 0.000007224 59.0
REGS2_k127_5334473_61 YicC-like family, N-terminal region - - - 0.00002207 51.0
REGS2_k127_5334473_7 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 597.0
REGS2_k127_5334473_8 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 568.0
REGS2_k127_5334473_9 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 562.0
REGS2_k127_5342432_0 Pfam ABC transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 361.0
REGS2_k127_5342432_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004322 231.0
REGS2_k127_5342432_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
REGS2_k127_5342432_3 response regulator K02282,K07705 - - 0.000000000000000000007593 96.0
REGS2_k127_5342432_4 Histidine kinase K07675 - 2.7.13.3 0.0000000002485 67.0
REGS2_k127_5358278_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 404.0
REGS2_k127_5380923_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 3.893e-253 787.0
REGS2_k127_5380923_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.315e-194 616.0
REGS2_k127_5380923_10 Short-chain dehydrogenase reductase SDR K00059,K11610 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0018454,GO:0019752,GO:0030497,GO:0032787,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046459,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000002068 188.0
REGS2_k127_5380923_11 HTH domain - - - 0.00000000000000000000000000000000000000000000001943 178.0
REGS2_k127_5380923_12 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000002878 153.0
REGS2_k127_5380923_13 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000003307 145.0
REGS2_k127_5380923_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000001017 145.0
REGS2_k127_5380923_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000001173 141.0
REGS2_k127_5380923_16 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000002424 108.0
REGS2_k127_5380923_17 transcriptional regulator - - - 0.000000000001069 73.0
REGS2_k127_5380923_18 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000268 53.0
REGS2_k127_5380923_19 - - - - 0.0003671 48.0
REGS2_k127_5380923_2 PFAM Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 632.0
REGS2_k127_5380923_3 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 401.0
REGS2_k127_5380923_4 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 394.0
REGS2_k127_5380923_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 395.0
REGS2_k127_5380923_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 394.0
REGS2_k127_5380923_7 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 359.0
REGS2_k127_5380923_8 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 331.0
REGS2_k127_5380923_9 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000001635 228.0
REGS2_k127_5414215_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 567.0
REGS2_k127_5414215_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 394.0
REGS2_k127_5414215_10 Putative zinc-finger - - - 0.00000001777 63.0
REGS2_k127_5414215_11 - - - - 0.00001158 48.0
REGS2_k127_5414215_2 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 327.0
REGS2_k127_5414215_3 water channel activity K02440,K06188,K09874 - - 0.00000000000000000000000000000000000000000000000000000000002774 216.0
REGS2_k127_5414215_4 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000001242 192.0
REGS2_k127_5414215_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000001347 192.0
REGS2_k127_5414215_6 Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000000000000008658 142.0
REGS2_k127_5414215_7 Flavin reductase like domain - - - 0.000000000000000000000000000000003458 146.0
REGS2_k127_5414215_8 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000003543 134.0
REGS2_k127_5414215_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000005132 73.0
REGS2_k127_5430021_0 IgGFc binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000105 257.0
REGS2_k127_5430021_1 Galactose oxidase, central domain - - - 0.000000000000000005703 98.0
REGS2_k127_5438948_0 Dehydrogenase - - - 3.201e-204 645.0
REGS2_k127_5438948_1 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 499.0
REGS2_k127_5438948_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 321.0
REGS2_k127_5438948_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000009126 199.0
REGS2_k127_5438948_5 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000002319 121.0
REGS2_k127_5438948_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000199 103.0
REGS2_k127_5438948_7 Glycosyltransferase family 87 K13671 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000004933 71.0
REGS2_k127_5438948_8 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.0000002345 62.0
REGS2_k127_5438948_9 Universal stress protein family - - - 0.0000004173 61.0
REGS2_k127_5481255_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 512.0
REGS2_k127_5481255_1 phosphorelay signal transduction system K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 413.0
REGS2_k127_5481255_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000001358 192.0
REGS2_k127_5481255_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000007671 162.0
REGS2_k127_5481255_5 - - - - 0.000000000000000000000006429 113.0
REGS2_k127_5481255_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000004543 100.0
REGS2_k127_5481255_7 - - - - 0.00000000000000425 80.0
REGS2_k127_5481255_8 SnoaL-like polyketide cyclase - - - 0.00000000773 60.0
REGS2_k127_5481255_9 Bacterial transcriptional activator domain - - - 0.0000009054 60.0
REGS2_k127_5496619_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 325.0
REGS2_k127_5496619_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000007503 191.0
REGS2_k127_5551628_0 Domain of unknown function (DUF3471) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 488.0
REGS2_k127_5551628_1 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000241 282.0
REGS2_k127_5551628_2 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000000005548 223.0
REGS2_k127_5551628_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000371 104.0
REGS2_k127_5551628_4 alginic acid biosynthetic process K10297 - - 0.0001355 51.0
REGS2_k127_5596429_0 TonB-dependent receptor K02014 - - 8.789e-205 671.0
REGS2_k127_5596429_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 368.0
REGS2_k127_5596429_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002145 255.0
REGS2_k127_5596429_3 TPM domain K06872 - - 0.000000000000000000000000000000000000000002282 164.0
REGS2_k127_56094_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000001125 224.0
REGS2_k127_56094_1 Fibronectin type 3 domain - - - 0.000000000000000000000005015 107.0
REGS2_k127_56094_2 WD40 repeat, subgroup - - - 0.00001311 59.0
REGS2_k127_5623823_0 RDD family K06384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 336.0
REGS2_k127_5623823_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000209 263.0
REGS2_k127_5623823_2 pathogenesis - - - 0.0000000000001038 83.0
REGS2_k127_5623823_3 Domain of unknown function (DUF4350) - - - 0.00000000001445 77.0
REGS2_k127_5623823_4 - - - - 0.00000002392 63.0
REGS2_k127_5623823_5 WD40-like Beta Propeller Repeat K03641 - - 0.00000008572 65.0
REGS2_k127_5623823_6 Parallel beta-helix repeats - - - 0.0000769 56.0
REGS2_k127_5623823_7 Archaeal Type IV pilin, N-terminal - - - 0.0001657 55.0
REGS2_k127_5644970_0 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 354.0
REGS2_k127_5644970_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000005386 170.0
REGS2_k127_5651135_0 cellulose binding - - - 4.282e-247 772.0
REGS2_k127_565388_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1240.0
REGS2_k127_565388_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.94e-308 955.0
REGS2_k127_565388_10 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 494.0
REGS2_k127_565388_11 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 490.0
REGS2_k127_565388_12 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 499.0
REGS2_k127_565388_13 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 473.0
REGS2_k127_565388_14 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 460.0
REGS2_k127_565388_15 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 380.0
REGS2_k127_565388_16 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 391.0
REGS2_k127_565388_17 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 364.0
REGS2_k127_565388_18 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 340.0
REGS2_k127_565388_19 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 332.0
REGS2_k127_565388_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.315e-298 934.0
REGS2_k127_565388_20 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 321.0
REGS2_k127_565388_21 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 327.0
REGS2_k127_565388_22 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 323.0
REGS2_k127_565388_23 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 302.0
REGS2_k127_565388_24 O-acyltransferase activity K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000004113 259.0
REGS2_k127_565388_25 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001299 280.0
REGS2_k127_565388_26 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000003788 243.0
REGS2_k127_565388_27 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000006767 214.0
REGS2_k127_565388_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000001051 224.0
REGS2_k127_565388_29 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000003021 180.0
REGS2_k127_565388_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.669e-276 883.0
REGS2_k127_565388_30 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000002397 175.0
REGS2_k127_565388_31 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000004964 176.0
REGS2_k127_565388_32 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000000002414 160.0
REGS2_k127_565388_33 OmpA family K03640 - - 0.00000000000000000000000000000000000002422 151.0
REGS2_k127_565388_34 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000006688 151.0
REGS2_k127_565388_35 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000001484 145.0
REGS2_k127_565388_36 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.000000000000000000000000000000002465 131.0
REGS2_k127_565388_37 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000009827 129.0
REGS2_k127_565388_38 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000000003694 139.0
REGS2_k127_565388_39 TPR repeat - - - 0.000000000000000000000000000000962 132.0
REGS2_k127_565388_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 7.551e-224 722.0
REGS2_k127_565388_40 Tetratricopeptide repeat - - - 0.000000000000000000000000000094 133.0
REGS2_k127_565388_41 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.000000000000000000000000000695 119.0
REGS2_k127_565388_42 TonB C terminal K03832 - - 0.000000000000000000000002407 116.0
REGS2_k127_565388_43 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000002497 113.0
REGS2_k127_565388_44 Domain of unknown function (DUF4321) - - - 0.0000000000000000000000126 102.0
REGS2_k127_565388_45 Modulates RecA activity K03565 - - 0.00000000000000000000009679 106.0
REGS2_k127_565388_46 Universal bacterial protein YeaZ K14742 - - 0.0000000000000000000001971 108.0
REGS2_k127_565388_47 Cytochrome C assembly protein - - - 0.000000000000000001018 97.0
REGS2_k127_565388_49 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000881 75.0
REGS2_k127_565388_5 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 612.0
REGS2_k127_565388_50 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000001351 61.0
REGS2_k127_565388_51 protein containing LysM domain - - - 0.000000001917 70.0
REGS2_k127_565388_52 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000002929 60.0
REGS2_k127_565388_53 Lysin motif - - - 0.00000003141 66.0
REGS2_k127_565388_6 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 599.0
REGS2_k127_565388_7 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 585.0
REGS2_k127_565388_8 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 585.0
REGS2_k127_565388_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 532.0
REGS2_k127_5666312_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1419.0
REGS2_k127_5666312_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.523e-261 824.0
REGS2_k127_5666312_10 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 530.0
REGS2_k127_5666312_11 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 514.0
REGS2_k127_5666312_12 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 435.0
REGS2_k127_5666312_13 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 415.0
REGS2_k127_5666312_14 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 409.0
REGS2_k127_5666312_15 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 377.0
REGS2_k127_5666312_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 332.0
REGS2_k127_5666312_17 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 333.0
REGS2_k127_5666312_18 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 316.0
REGS2_k127_5666312_19 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 321.0
REGS2_k127_5666312_2 COG0433 Predicted ATPase K06915 - - 7.501e-257 808.0
REGS2_k127_5666312_20 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 280.0
REGS2_k127_5666312_21 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005871 297.0
REGS2_k127_5666312_22 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002327 269.0
REGS2_k127_5666312_23 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004535 258.0
REGS2_k127_5666312_24 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008349 269.0
REGS2_k127_5666312_25 COGs COG1172 Ribose xylose arabinose galactoside ABC-type transport systems permease components K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000002072 239.0
REGS2_k127_5666312_26 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000005208 241.0
REGS2_k127_5666312_27 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000002564 234.0
REGS2_k127_5666312_28 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000004118 229.0
REGS2_k127_5666312_29 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000119 191.0
REGS2_k127_5666312_3 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 5.696e-252 793.0
REGS2_k127_5666312_30 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000002147 187.0
REGS2_k127_5666312_31 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000001885 185.0
REGS2_k127_5666312_32 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000129 178.0
REGS2_k127_5666312_33 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000001654 182.0
REGS2_k127_5666312_34 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000004025 162.0
REGS2_k127_5666312_35 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000001595 168.0
REGS2_k127_5666312_36 ATP-binding protein K19340 - - 0.00000000000000000000000000000000000005183 156.0
REGS2_k127_5666312_37 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000006026 131.0
REGS2_k127_5666312_38 COGs COG2380 conserved - - - 0.000000000000000000000000000004772 137.0
REGS2_k127_5666312_4 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 597.0
REGS2_k127_5666312_40 sensor histidine kinase response - - - 0.00000000000000000000003036 109.0
REGS2_k127_5666312_41 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000009058 98.0
REGS2_k127_5666312_42 subunit of a heme lyase K02200 - - 0.000000000000000000005886 109.0
REGS2_k127_5666312_43 - - - - 0.0000000000000000001938 95.0
REGS2_k127_5666312_44 Protein of unknown function (DUF721) - - - 0.0000000000000000002387 92.0
REGS2_k127_5666312_45 4-vinyl reductase, 4VR - - - 0.0000000000000000198 89.0
REGS2_k127_5666312_46 - - - - 0.000000000000000167 86.0
REGS2_k127_5666312_47 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000006896 78.0
REGS2_k127_5666312_48 Peptidase, M23 family - - - 0.0000000000002352 84.0
REGS2_k127_5666312_49 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000000001157 74.0
REGS2_k127_5666312_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 600.0
REGS2_k127_5666312_50 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000001884 66.0
REGS2_k127_5666312_51 Acetyltransferase (GNAT) domain - - - 0.000001929 59.0
REGS2_k127_5666312_52 - - - - 0.000005493 53.0
REGS2_k127_5666312_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 599.0
REGS2_k127_5666312_7 AAA domain K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 559.0
REGS2_k127_5666312_8 DALR_2 K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 524.0
REGS2_k127_5666312_9 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 539.0
REGS2_k127_5748237_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1304.0
REGS2_k127_5748237_1 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 542.0
REGS2_k127_5748237_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 426.0
REGS2_k127_5748237_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 345.0
REGS2_k127_5748237_4 domain, Protein K01179,K07260,K13735 - 3.2.1.4,3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000571 232.0
REGS2_k127_5748237_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000001383 200.0
REGS2_k127_5748237_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000279 173.0
REGS2_k127_5748237_7 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000001055 100.0
REGS2_k127_5748237_8 Sodium/hydrogen exchanger family - - - 0.000000003447 72.0
REGS2_k127_5788143_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.269e-285 891.0
REGS2_k127_5788143_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 361.0
REGS2_k127_5788143_2 - - - - 0.00003488 50.0
REGS2_k127_5828480_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.688e-267 839.0
REGS2_k127_5828480_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.198e-216 710.0
REGS2_k127_5828480_10 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 368.0
REGS2_k127_5828480_11 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 368.0
REGS2_k127_5828480_12 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 356.0
REGS2_k127_5828480_13 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 348.0
REGS2_k127_5828480_14 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 331.0
REGS2_k127_5828480_15 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 324.0
REGS2_k127_5828480_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 327.0
REGS2_k127_5828480_17 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 338.0
REGS2_k127_5828480_18 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
REGS2_k127_5828480_19 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001365 250.0
REGS2_k127_5828480_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 2.779e-201 641.0
REGS2_k127_5828480_20 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000002985 237.0
REGS2_k127_5828480_21 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001083 228.0
REGS2_k127_5828480_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000011 241.0
REGS2_k127_5828480_23 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000004534 225.0
REGS2_k127_5828480_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000005146 217.0
REGS2_k127_5828480_25 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000001494 179.0
REGS2_k127_5828480_26 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000007906 179.0
REGS2_k127_5828480_27 - - - - 0.000000000000000000000000000000000000000000000766 186.0
REGS2_k127_5828480_28 phosphonoacetaldehyde hydrolase activity K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000006797 163.0
REGS2_k127_5828480_29 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000002131 160.0
REGS2_k127_5828480_3 Sodium/hydrogen exchanger family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 493.0
REGS2_k127_5828480_30 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000006493 132.0
REGS2_k127_5828480_31 Glycosyl transferase family 2 - - - 0.000000000000000000000000002417 121.0
REGS2_k127_5828480_32 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000000001687 109.0
REGS2_k127_5828480_33 - - - - 0.00000000000000000000001808 114.0
REGS2_k127_5828480_34 chaperone-mediated protein folding - - - 0.0000000000000005657 92.0
REGS2_k127_5828480_35 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000348 83.0
REGS2_k127_5828480_36 Tetratricopeptide repeat - - - 0.0000000003701 70.0
REGS2_k127_5828480_37 chaperone-mediated protein folding - - - 0.000002538 60.0
REGS2_k127_5828480_4 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 474.0
REGS2_k127_5828480_5 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 446.0
REGS2_k127_5828480_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 441.0
REGS2_k127_5828480_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 433.0
REGS2_k127_5828480_8 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 402.0
REGS2_k127_5828480_9 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 394.0
REGS2_k127_5864811_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 558.0
REGS2_k127_5864811_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 450.0
REGS2_k127_5918411_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000009067 168.0
REGS2_k127_5918411_1 Dystroglycan-type cadherin-like domains. K07004 - - 0.000535 53.0
REGS2_k127_6061551_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 408.0
REGS2_k127_6061551_1 - - - - 0.000000000000000000000000000001079 128.0
REGS2_k127_6061551_2 CarboxypepD_reg-like domain - - - 0.00000000000000002776 96.0
REGS2_k127_6085201_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 589.0
REGS2_k127_6085201_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 540.0
REGS2_k127_6085201_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 388.0
REGS2_k127_6085201_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000004779 211.0
REGS2_k127_6085201_4 - K07274 - - 0.00000000000000000000000000000000000000000000000003961 196.0
REGS2_k127_6085201_5 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000004518 184.0
REGS2_k127_6085201_6 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000008809 147.0
REGS2_k127_6085201_7 Trypsin-like peptidase domain - - - 0.00000000000000002385 96.0
REGS2_k127_6085201_8 Cysteine-rich secretory protein family - - - 0.000001333 61.0
REGS2_k127_6090659_0 Major Facilitator Superfamily K08177 - - 6.017e-217 687.0
REGS2_k127_6090659_1 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 331.0
REGS2_k127_6090659_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 298.0
REGS2_k127_6090659_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000018 267.0
REGS2_k127_6090659_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001303 216.0
REGS2_k127_6090659_5 - - - - 0.0000000000000000000000000000000000000000000000000608 188.0
REGS2_k127_6090659_6 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000006787 58.0
REGS2_k127_610093_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 529.0
REGS2_k127_610093_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 456.0
REGS2_k127_610093_10 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004592 283.0
REGS2_k127_610093_11 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009707 276.0
REGS2_k127_610093_12 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000003181 253.0
REGS2_k127_610093_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000001849 175.0
REGS2_k127_610093_14 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000001799 112.0
REGS2_k127_610093_15 - - - - 0.0000000000000002417 87.0
REGS2_k127_610093_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 454.0
REGS2_k127_610093_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 417.0
REGS2_k127_610093_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 402.0
REGS2_k127_610093_5 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 399.0
REGS2_k127_610093_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 370.0
REGS2_k127_610093_7 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 356.0
REGS2_k127_610093_8 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 366.0
REGS2_k127_610093_9 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 333.0
REGS2_k127_6105452_0 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.000000000000000000000000000000000000000000000000000008713 206.0
REGS2_k127_6105452_1 Glycosyl transferases group 1 - - - 0.000000000000000000000002759 107.0
REGS2_k127_6105452_2 Glycosyl transferase, family 2 - - - 0.000000006279 61.0
REGS2_k127_6118841_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.54e-214 691.0
REGS2_k127_6118841_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 586.0
REGS2_k127_6118841_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009262 273.0
REGS2_k127_6118841_11 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005645 266.0
REGS2_k127_6118841_12 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000003736 180.0
REGS2_k127_6118841_13 Fimbrial assembly protein (PilN) - - - 0.00000000000000000000000000000000000008939 154.0
REGS2_k127_6118841_14 - - - - 0.0000000000000000000000000000000000004535 151.0
REGS2_k127_6118841_15 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000007277 129.0
REGS2_k127_6118841_16 Diguanylate cyclase - - - 0.000000000000000000000000000003167 138.0
REGS2_k127_6118841_17 - - - - 0.0000000000000000000000002731 111.0
REGS2_k127_6118841_18 Helix-turn-helix domain - - - 0.00000000000000000000005918 107.0
REGS2_k127_6118841_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.0000000000000000000001974 111.0
REGS2_k127_6118841_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 584.0
REGS2_k127_6118841_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 571.0
REGS2_k127_6118841_4 AMIN domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 518.0
REGS2_k127_6118841_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 488.0
REGS2_k127_6118841_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 437.0
REGS2_k127_6118841_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 417.0
REGS2_k127_6118841_8 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 333.0
REGS2_k127_6118841_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 351.0
REGS2_k127_6139270_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.954e-203 673.0
REGS2_k127_6139270_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 506.0
REGS2_k127_6139270_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 470.0
REGS2_k127_6139270_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 383.0
REGS2_k127_6139270_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 264.0
REGS2_k127_6139270_5 - - - - 0.000000000000002056 84.0
REGS2_k127_6139270_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0002532 48.0
REGS2_k127_6141556_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1239.0
REGS2_k127_6141556_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 320.0
REGS2_k127_6141556_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006008 268.0
REGS2_k127_6141556_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
REGS2_k127_6141556_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000007165 181.0
REGS2_k127_6141556_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000003848 135.0
REGS2_k127_6141556_6 Ribosomal protein L33 K02913 - - 0.000000000000000009264 83.0
REGS2_k127_6141556_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000003397 75.0
REGS2_k127_6141556_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000005405 59.0
REGS2_k127_6211075_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 514.0
REGS2_k127_6211075_1 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 461.0
REGS2_k127_6211075_10 - - - - 0.0000006938 56.0
REGS2_k127_6211075_11 Peptidase M1 membrane alanine aminopeptidase - - - 0.000006383 59.0
REGS2_k127_6211075_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 410.0
REGS2_k127_6211075_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 400.0
REGS2_k127_6211075_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000003648 117.0
REGS2_k127_6211075_5 phosphorelay signal transduction system - - - 0.00000000000000006376 91.0
REGS2_k127_6211075_6 YCII-related domain - - - 0.000000000001197 74.0
REGS2_k127_6211075_7 Alpha/beta hydrolase family - - - 0.000000000005006 71.0
REGS2_k127_6211075_8 HEAT repeats - - - 0.00000001942 66.0
REGS2_k127_6211075_9 - - - - 0.00000008848 59.0
REGS2_k127_6244535_0 protein secretion by the type I secretion system K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 565.0
REGS2_k127_6244535_1 Histidine kinase K00936,K02030 - 2.7.13.3 0.0000000000000000000000000000000000000001055 162.0
REGS2_k127_6296708_0 NAD synthase K01916 - 6.3.1.5 3.347e-206 659.0
REGS2_k127_6296708_1 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000002462 192.0
REGS2_k127_6296708_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000008682 146.0
REGS2_k127_6296708_3 S23 ribosomal protein - - - 0.00000000006573 68.0
REGS2_k127_6296931_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 541.0
REGS2_k127_6296931_1 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 495.0
REGS2_k127_6296931_2 protein import - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 403.0
REGS2_k127_6296931_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 290.0
REGS2_k127_6296931_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000001149 189.0
REGS2_k127_6296931_5 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000007733 147.0
REGS2_k127_6296931_7 oxidoreductase K17218 - 1.8.5.4 0.000001104 50.0
REGS2_k127_6297809_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 358.0
REGS2_k127_6297809_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001054 284.0
REGS2_k127_6297809_2 ABC transporter K06158 - - 0.000000000006455 67.0
REGS2_k127_6317739_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 4.224e-238 743.0
REGS2_k127_6317739_1 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000001054 218.0
REGS2_k127_6317739_2 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000000000004475 198.0
REGS2_k127_6317739_3 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000001052 137.0
REGS2_k127_6318737_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 332.0
REGS2_k127_6318737_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 309.0
REGS2_k127_6318737_10 - - - - 0.0000000000000007538 78.0
REGS2_k127_6318737_12 CAAX protease self-immunity - - - 0.00000000001868 76.0
REGS2_k127_6318737_2 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 290.0
REGS2_k127_6318737_3 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001586 237.0
REGS2_k127_6318737_4 COG1651 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000003872 230.0
REGS2_k127_6318737_5 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000000000000000000834 218.0
REGS2_k127_6318737_6 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000002266 199.0
REGS2_k127_6318737_7 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000003984 203.0
REGS2_k127_6318737_8 - - - - 0.00000000000000000000000000000004846 127.0
REGS2_k127_6318737_9 - - - - 0.0000000000000000000002728 98.0
REGS2_k127_6356027_0 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.728e-231 727.0
REGS2_k127_6356027_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 434.0
REGS2_k127_6461455_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 5.489e-300 934.0
REGS2_k127_6461455_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 8.815e-209 664.0
REGS2_k127_6461455_10 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000049 267.0
REGS2_k127_6461455_11 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001938 261.0
REGS2_k127_6461455_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000216 252.0
REGS2_k127_6461455_13 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000001341 220.0
REGS2_k127_6461455_14 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000002168 230.0
REGS2_k127_6461455_15 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007793 216.0
REGS2_k127_6461455_16 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000001717 196.0
REGS2_k127_6461455_17 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000009149 195.0
REGS2_k127_6461455_18 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000001924 190.0
REGS2_k127_6461455_19 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000003136 186.0
REGS2_k127_6461455_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 543.0
REGS2_k127_6461455_20 Cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000004415 177.0
REGS2_k127_6461455_21 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000009125 178.0
REGS2_k127_6461455_22 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000008154 162.0
REGS2_k127_6461455_23 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000001883 149.0
REGS2_k127_6461455_24 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000002714 144.0
REGS2_k127_6461455_25 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000004135 147.0
REGS2_k127_6461455_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000001616 118.0
REGS2_k127_6461455_27 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000006697 115.0
REGS2_k127_6461455_28 - - - - 0.0000000000000000000139 99.0
REGS2_k127_6461455_29 Helix-turn-helix domain - - - 0.000000000002015 77.0
REGS2_k127_6461455_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 409.0
REGS2_k127_6461455_30 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00000000003075 75.0
REGS2_k127_6461455_31 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.0000000004355 70.0
REGS2_k127_6461455_33 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0003578 51.0
REGS2_k127_6461455_4 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 404.0
REGS2_k127_6461455_5 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 377.0
REGS2_k127_6461455_6 AsnC-type helix-turn-helix domain K05710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 332.0
REGS2_k127_6461455_7 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 337.0
REGS2_k127_6461455_8 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 316.0
REGS2_k127_6461455_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
REGS2_k127_6497021_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0 1188.0
REGS2_k127_6497021_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.073e-215 696.0
REGS2_k127_6497021_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000004202 226.0
REGS2_k127_6497021_11 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000006167 224.0
REGS2_k127_6497021_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000001279 201.0
REGS2_k127_6497021_13 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.00000000000000000000000000000000000000001389 166.0
REGS2_k127_6497021_14 PFAM Diacylglycerol kinase, catalytic - - - 0.0000000000000000000000000000000000000001544 166.0
REGS2_k127_6497021_15 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000007327 149.0
REGS2_k127_6497021_16 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000009862 148.0
REGS2_k127_6497021_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000003526 113.0
REGS2_k127_6497021_18 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000005171 113.0
REGS2_k127_6497021_19 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000004975 105.0
REGS2_k127_6497021_2 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 1.957e-213 678.0
REGS2_k127_6497021_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000001053 101.0
REGS2_k127_6497021_21 Protein conserved in bacteria K09764 - - 0.0000000000000006306 82.0
REGS2_k127_6497021_22 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.00000000000006824 75.0
REGS2_k127_6497021_23 - - - - 0.0000002423 63.0
REGS2_k127_6497021_3 Tetratricopeptide repeat - - - 3.008e-209 676.0
REGS2_k127_6497021_4 Participates in both transcription termination and antitermination K02600 - - 6.457e-196 620.0
REGS2_k127_6497021_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 499.0
REGS2_k127_6497021_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 359.0
REGS2_k127_6497021_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
REGS2_k127_6497021_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 316.0
REGS2_k127_6497021_9 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001566 283.0
REGS2_k127_6502894_0 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 497.0
REGS2_k127_6502894_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 415.0
REGS2_k127_6502894_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 314.0
REGS2_k127_6502894_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000001828 145.0
REGS2_k127_654487_0 cellulose binding - - - 0.0 1064.0
REGS2_k127_654487_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 542.0
REGS2_k127_6598099_0 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 367.0
REGS2_k127_6598099_1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 319.0
REGS2_k127_6598099_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000481 160.0
REGS2_k127_6646569_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
REGS2_k127_6646569_1 - - - - 0.0000000000000000000000000000000000000000001739 170.0
REGS2_k127_6646569_2 - - - - 0.00000000000000000000000000001035 118.0
REGS2_k127_6646569_3 - - - - 0.000000002371 66.0
REGS2_k127_674992_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.919e-286 887.0
REGS2_k127_6903764_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 483.0
REGS2_k127_6903764_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 406.0
REGS2_k127_6903764_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 374.0
REGS2_k127_6903764_3 Protein of unknown function (DUF1207) - - - 0.00000000000000000000000000000000000000000000000000000000000000002478 233.0
REGS2_k127_6903764_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000001844 184.0
REGS2_k127_6970687_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 481.0
REGS2_k127_6970687_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000001039 256.0
REGS2_k127_6970687_2 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000003192 171.0
REGS2_k127_6970687_3 DinB family - - - 0.000000000000000000000000000000000000000001525 161.0
REGS2_k127_6970687_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000004468 162.0
REGS2_k127_6970687_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000006225 162.0
REGS2_k127_6970687_6 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000002346 128.0
REGS2_k127_6970687_8 CDP-alcohol phosphatidyltransferase K07291 - 2.7.8.34 0.000000000627 70.0
REGS2_k127_6970687_9 Psort location Cytoplasmic, score 8.96 - - - 0.0003852 45.0
REGS2_k127_6979068_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1281.0
REGS2_k127_6979068_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 486.0
REGS2_k127_6979068_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 445.0
REGS2_k127_6979068_3 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001538 295.0
REGS2_k127_6979068_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000001799 216.0
REGS2_k127_6979068_5 Export-related chaperone CsaA K06878 - - 0.000000000000000000000000000000000000000001094 160.0
REGS2_k127_6979068_6 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000004148 157.0
REGS2_k127_6979068_7 - - - - 0.0000000000000003051 88.0
REGS2_k127_6988781_0 Sortilin, neurotensin receptor 3, - - - 0.0 1361.0
REGS2_k127_6988781_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 489.0
REGS2_k127_6988781_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
REGS2_k127_6988781_3 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001885 215.0
REGS2_k127_6988781_4 Metal binding domain of Ada K10778 - 2.1.1.63 0.00000000000000000000000000000000000008561 159.0
REGS2_k127_6988781_5 Belongs to the GcvT family K00605,K17486 - 2.1.1.269,2.1.2.10 0.0000000000000000000000000006838 117.0
REGS2_k127_6988781_7 Protein of unknown function (DUF2892) - - - 0.0000000003305 68.0
REGS2_k127_6998977_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 2.055e-200 635.0
REGS2_k127_6998977_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000003556 183.0
REGS2_k127_6998977_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000002062 113.0
REGS2_k127_6998977_3 endonuclease III K01247 - 3.2.2.21 0.0000000000006607 71.0
REGS2_k127_7045832_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1035.0
REGS2_k127_7045832_1 Uncharacterized protein family (UPF0051) K09014 - - 1.836e-261 809.0
REGS2_k127_7045832_10 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 516.0
REGS2_k127_7045832_11 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 505.0
REGS2_k127_7045832_12 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 406.0
REGS2_k127_7045832_13 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 413.0
REGS2_k127_7045832_14 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
REGS2_k127_7045832_15 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 375.0
REGS2_k127_7045832_16 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 370.0
REGS2_k127_7045832_17 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 377.0
REGS2_k127_7045832_18 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 361.0
REGS2_k127_7045832_19 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 378.0
REGS2_k127_7045832_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.48e-249 793.0
REGS2_k127_7045832_20 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 351.0
REGS2_k127_7045832_21 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 373.0
REGS2_k127_7045832_22 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 328.0
REGS2_k127_7045832_23 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 307.0
REGS2_k127_7045832_24 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 317.0
REGS2_k127_7045832_25 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005576 287.0
REGS2_k127_7045832_26 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006261 282.0
REGS2_k127_7045832_27 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001166 269.0
REGS2_k127_7045832_28 Fe-S protein K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 258.0
REGS2_k127_7045832_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000009242 260.0
REGS2_k127_7045832_3 Zinc carboxypeptidase - - - 2.06e-243 775.0
REGS2_k127_7045832_30 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 258.0
REGS2_k127_7045832_31 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000002175 252.0
REGS2_k127_7045832_32 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000003211 245.0
REGS2_k127_7045832_33 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000379 240.0
REGS2_k127_7045832_34 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000007766 238.0
REGS2_k127_7045832_35 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000003137 232.0
REGS2_k127_7045832_36 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000007847 220.0
REGS2_k127_7045832_37 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000002284 219.0
REGS2_k127_7045832_38 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000009947 190.0
REGS2_k127_7045832_39 - - - - 0.000000000000000000000000000000000000000000000000005958 195.0
REGS2_k127_7045832_4 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 2.25e-240 760.0
REGS2_k127_7045832_40 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000006023 187.0
REGS2_k127_7045832_41 Mazg nucleotide pyrophosphohydrolase K00800 - 2.5.1.19 0.000000000000000000000000000000000000002697 153.0
REGS2_k127_7045832_42 - - - - 0.00000000000000000000000000000000008029 149.0
REGS2_k127_7045832_43 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000588 134.0
REGS2_k127_7045832_44 - - - - 0.000000000000000000000000000001438 123.0
REGS2_k127_7045832_45 HEAT repeat - - - 0.000000000000000000000000000003374 137.0
REGS2_k127_7045832_46 Peptidase, M23 - - - 0.0000000000000000000000000002451 124.0
REGS2_k127_7045832_47 - - - - 0.000000000000000000000002759 116.0
REGS2_k127_7045832_48 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000001077 108.0
REGS2_k127_7045832_49 Domain of unknown function (DUF4034) - - - 0.0000000000000000000001568 111.0
REGS2_k127_7045832_5 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.326e-215 692.0
REGS2_k127_7045832_50 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000004634 100.0
REGS2_k127_7045832_51 TonB-dependent receptor - - - 0.00000000000000189 91.0
REGS2_k127_7045832_52 - - - - 0.000000000000008877 86.0
REGS2_k127_7045832_53 - - - - 0.0000000000005019 72.0
REGS2_k127_7045832_54 Domain of unknown function (DUF4382) - - - 0.000000000001765 81.0
REGS2_k127_7045832_55 DnaJ molecular chaperone homology domain - - - 0.0000000001845 72.0
REGS2_k127_7045832_56 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000001108 62.0
REGS2_k127_7045832_57 Sugar-specific transcriptional regulator TrmB - - - 0.00000002547 66.0
REGS2_k127_7045832_58 COG0457 FOG TPR repeat - - - 0.0000636 55.0
REGS2_k127_7045832_6 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 589.0
REGS2_k127_7045832_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 587.0
REGS2_k127_7045832_8 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 564.0
REGS2_k127_7045832_9 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 544.0
REGS2_k127_7052383_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 7.229e-292 911.0
REGS2_k127_7052383_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 571.0
REGS2_k127_7052383_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 419.0
REGS2_k127_7052383_3 ribonuclease E activity K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 391.0
REGS2_k127_7052383_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000002686 131.0
REGS2_k127_7052383_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000005591 129.0
REGS2_k127_7052383_6 Protein of unknown function (DUF1003) - - - 0.0000000000004653 76.0
REGS2_k127_7079350_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 586.0
REGS2_k127_7079350_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 305.0
REGS2_k127_7079350_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 256.0
REGS2_k127_7079350_3 Belongs to the peptidase S26 family - - - 0.00000000000000000000000000000000000001576 147.0
REGS2_k127_7079350_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000189 147.0
REGS2_k127_7079350_5 lipid binding - - - 0.00000000000000000000002374 104.0
REGS2_k127_7081824_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.994e-213 692.0
REGS2_k127_7081824_1 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 572.0
REGS2_k127_7081824_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001192 274.0
REGS2_k127_7081824_11 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006971 230.0
REGS2_k127_7081824_12 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000001936 199.0
REGS2_k127_7081824_13 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000004941 116.0
REGS2_k127_7081824_14 - - - - 0.00000000000000000000001332 108.0
REGS2_k127_7081824_15 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000001253 81.0
REGS2_k127_7081824_18 chlorophyll binding K02040,K03286,K21218 - - 0.00000007897 64.0
REGS2_k127_7081824_19 AMP-binding enzyme C-terminal domain K00666 - - 0.000008726 53.0
REGS2_k127_7081824_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 545.0
REGS2_k127_7081824_3 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 533.0
REGS2_k127_7081824_4 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 491.0
REGS2_k127_7081824_5 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 440.0
REGS2_k127_7081824_6 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 423.0
REGS2_k127_7081824_7 surface antigen K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 321.0
REGS2_k127_7081824_8 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 289.0
REGS2_k127_7081824_9 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006428 283.0
REGS2_k127_7143697_0 Peptidase family M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 371.0
REGS2_k127_7143697_1 DJ-1/PfpI family - - - 0.000000000000000000000000000002703 125.0
REGS2_k127_7155597_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 5.708e-222 703.0
REGS2_k127_7155597_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 460.0
REGS2_k127_7155597_10 PFAM glycoside hydrolase family 13 domain protein - - - 0.00000000000000000002115 101.0
REGS2_k127_7155597_12 domain protein K13735 - - 0.00000000000000000007134 102.0
REGS2_k127_7155597_13 SMART zinc finger CDGSH-type domain protein - - - 0.0000000000002692 75.0
REGS2_k127_7155597_14 - - - - 0.00000000001004 67.0
REGS2_k127_7155597_15 DoxX K15977 - - 0.00000000003036 71.0
REGS2_k127_7155597_17 - - - - 0.000001258 61.0
REGS2_k127_7155597_18 Bacterial Ig-like domain 2 - - - 0.000246 53.0
REGS2_k127_7155597_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 337.0
REGS2_k127_7155597_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 302.0
REGS2_k127_7155597_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000001906 233.0
REGS2_k127_7155597_5 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000006561 181.0
REGS2_k127_7155597_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000001547 151.0
REGS2_k127_7155597_7 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000005694 145.0
REGS2_k127_7155597_8 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000004134 123.0
REGS2_k127_7155597_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000001162 102.0
REGS2_k127_7158338_0 Prolyl oligopeptidase family - - - 6.057e-214 679.0
REGS2_k127_7158338_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 507.0
REGS2_k127_7158338_2 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 489.0
REGS2_k127_7158338_3 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000004056 158.0
REGS2_k127_7298753_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 357.0
REGS2_k127_7298753_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009101 253.0
REGS2_k127_7298753_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000002617 239.0
REGS2_k127_7298753_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.000000000000000000000000000000000000001056 154.0
REGS2_k127_7298753_4 - - - - 0.0000000000000000000000000000000001968 144.0
REGS2_k127_7298753_5 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000001034 144.0
REGS2_k127_7298753_6 Pfam Response regulator receiver K11443 - - 0.0000000000000000000005117 106.0
REGS2_k127_7313079_0 aconitate hydratase K01681 - 4.2.1.3 8.268e-226 712.0
REGS2_k127_7313079_1 - - - - 0.00000000000000000000000000000000000000000000004701 171.0
REGS2_k127_7313079_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000003484 168.0
REGS2_k127_7413576_0 PglZ domain - - - 4.045e-198 631.0
REGS2_k127_7413576_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 479.0
REGS2_k127_7413576_10 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000003385 212.0
REGS2_k127_7413576_11 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000006947 210.0
REGS2_k127_7413576_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000009803 183.0
REGS2_k127_7413576_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.0000000000000000000000000000000000000000002113 165.0
REGS2_k127_7413576_14 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000009591 173.0
REGS2_k127_7413576_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000003381 153.0
REGS2_k127_7413576_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000009328 109.0
REGS2_k127_7413576_17 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000003098 85.0
REGS2_k127_7413576_18 thiamine biosynthesis protein ThiS K03154 - - 0.000000000004225 72.0
REGS2_k127_7413576_19 Preprotein translocase subunit K03210 - - 0.00000000001318 74.0
REGS2_k127_7413576_2 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 488.0
REGS2_k127_7413576_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 458.0
REGS2_k127_7413576_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 372.0
REGS2_k127_7413576_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 315.0
REGS2_k127_7413576_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 312.0
REGS2_k127_7413576_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 314.0
REGS2_k127_7413576_8 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
REGS2_k127_7413576_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000191 250.0
REGS2_k127_7499853_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 470.0
REGS2_k127_7499853_1 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 420.0
REGS2_k127_7499853_10 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000009785 143.0
REGS2_k127_7499853_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000009518 90.0
REGS2_k127_7499853_13 - - - - 0.0001969 49.0
REGS2_k127_7499853_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 404.0
REGS2_k127_7499853_3 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 372.0
REGS2_k127_7499853_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 327.0
REGS2_k127_7499853_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004802 248.0
REGS2_k127_7499853_6 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000003468 215.0
REGS2_k127_7499853_7 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000684 171.0
REGS2_k127_7499853_8 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000003415 158.0
REGS2_k127_7499853_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000003965 156.0
REGS2_k127_7604659_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.968e-214 681.0
REGS2_k127_7604659_1 phosphoribosyltransferase K07100 - - 0.00000000002027 72.0
REGS2_k127_7605182_0 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000005571 224.0
REGS2_k127_7605182_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000002695 134.0
REGS2_k127_7759238_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 516.0
REGS2_k127_7759238_1 - - - - 0.0000000000002845 83.0
REGS2_k127_7800591_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 501.0
REGS2_k127_7800591_1 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 473.0
REGS2_k127_7800591_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 254.0
REGS2_k127_7800591_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002918 252.0
REGS2_k127_7800591_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000001312 62.0
REGS2_k127_7807900_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000006682 212.0
REGS2_k127_7808449_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.041e-221 700.0
REGS2_k127_7808449_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.073e-205 657.0
REGS2_k127_7808449_10 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000803 250.0
REGS2_k127_7808449_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006206 262.0
REGS2_k127_7808449_12 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000001255 248.0
REGS2_k127_7808449_13 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000001919 231.0
REGS2_k127_7808449_14 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000000001441 154.0
REGS2_k127_7808449_15 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000004815 147.0
REGS2_k127_7808449_16 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000002296 128.0
REGS2_k127_7808449_17 Regulatory protein, FmdB family - - - 0.0000000000000000005488 89.0
REGS2_k127_7808449_18 PQQ-like domain K17713 - - 0.00000000000000001307 96.0
REGS2_k127_7808449_19 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000002786 82.0
REGS2_k127_7808449_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 570.0
REGS2_k127_7808449_20 - - - - 0.000000000000001557 90.0
REGS2_k127_7808449_21 Antibiotic biosynthesis monooxygenase - - - 0.00000000009909 70.0
REGS2_k127_7808449_22 Late competence development protein ComFB - - - 0.000000001526 70.0
REGS2_k127_7808449_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 577.0
REGS2_k127_7808449_4 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 565.0
REGS2_k127_7808449_5 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 464.0
REGS2_k127_7808449_6 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
REGS2_k127_7808449_7 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 376.0
REGS2_k127_7808449_8 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 324.0
REGS2_k127_7808449_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 306.0
REGS2_k127_7810694_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 411.0
REGS2_k127_7810694_1 PFAM Aldehyde dehydrogenase family K00128,K00131,K00146,K00151,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.60,1.2.1.85,1.2.1.9 0.00000000000000000000000000000000000000000000000000008251 190.0
REGS2_k127_7810694_2 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000007693 185.0
REGS2_k127_7810694_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000000216 166.0
REGS2_k127_7849444_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 4.859e-295 927.0
REGS2_k127_7849444_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 515.0
REGS2_k127_7849444_10 cellulose binding - - - 0.0000000000000000000000000000000004925 135.0
REGS2_k127_7849444_11 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000001439 136.0
REGS2_k127_7849444_12 - - - - 0.00000000000000000000000000000003836 134.0
REGS2_k127_7849444_13 Domain of unknown function (DUF4382) - - - 0.00000000000000000006917 101.0
REGS2_k127_7849444_15 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000005735 87.0
REGS2_k127_7849444_16 Glycosyltransferase family 87 - - - 0.0000000000004392 82.0
REGS2_k127_7849444_17 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000006636 68.0
REGS2_k127_7849444_18 - - - - 0.00000004017 65.0
REGS2_k127_7849444_19 Putative 2OG-Fe(II) oxygenase - - - 0.0000003245 64.0
REGS2_k127_7849444_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 372.0
REGS2_k127_7849444_20 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.00001194 57.0
REGS2_k127_7849444_21 - - - - 0.000512 51.0
REGS2_k127_7849444_3 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 315.0
REGS2_k127_7849444_4 Rubrerythrin K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008096 291.0
REGS2_k127_7849444_5 - - - - 0.00000000000000000000000000000000000000000000001335 180.0
REGS2_k127_7849444_6 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000001761 160.0
REGS2_k127_7849444_7 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000002005 159.0
REGS2_k127_7849444_8 protein tyrosine kinase activity K03593 - - 0.000000000000000000000000000000000000006163 157.0
REGS2_k127_7849444_9 iron-sulfur cluster assembly K07400 - - 0.0000000000000000000000000000000000004385 147.0
REGS2_k127_7907867_0 Involved in the tonB-independent uptake of proteins - - - 6.106e-303 964.0
REGS2_k127_7907867_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 1.219e-245 773.0
REGS2_k127_7907867_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000004432 151.0
REGS2_k127_7907867_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000006351 135.0
REGS2_k127_7907867_13 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000114 146.0
REGS2_k127_7907867_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000004633 105.0
REGS2_k127_7907867_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000004035 102.0
REGS2_k127_7907867_16 - - - - 0.0000000001409 72.0
REGS2_k127_7907867_2 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 8.069e-223 713.0
REGS2_k127_7907867_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 565.0
REGS2_k127_7907867_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 467.0
REGS2_k127_7907867_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 465.0
REGS2_k127_7907867_6 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 443.0
REGS2_k127_7907867_7 Dihydroxyacetone kinase family K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 335.0
REGS2_k127_7907867_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000166 188.0
REGS2_k127_7907867_9 Sporulation related domain - - - 0.0000000000000000000000000000000000000003937 166.0
REGS2_k127_7916360_0 ABC transporter K06158 - - 7.86e-247 777.0
REGS2_k127_7916360_1 DinB superfamily - - - 0.000000000001046 68.0
REGS2_k127_7916360_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000001143 66.0
REGS2_k127_7927976_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 554.0
REGS2_k127_7927976_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 499.0
REGS2_k127_7927976_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000003467 176.0
REGS2_k127_7927976_11 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000001823 165.0
REGS2_k127_7927976_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.0000000000000000413 82.0
REGS2_k127_7927976_13 Belongs to the 'phage' integrase family - - - 0.000000000000002081 78.0
REGS2_k127_7927976_14 TonB-dependent Receptor Plug Domain - - - 0.000001106 62.0
REGS2_k127_7927976_15 long-chain fatty acid transporting porin activity - - - 0.0005479 52.0
REGS2_k127_7927976_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 459.0
REGS2_k127_7927976_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 437.0
REGS2_k127_7927976_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 368.0
REGS2_k127_7927976_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 264.0
REGS2_k127_7927976_6 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
REGS2_k127_7927976_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000001258 237.0
REGS2_k127_7927976_8 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000165 190.0
REGS2_k127_7927976_9 - - - - 0.000000000000000000000000000000000000000000000004348 186.0
REGS2_k127_7976990_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 441.0
REGS2_k127_7976990_1 ABC transporter transmembrane region K02021 - - 0.00000000000000000000000000000000000000000000000000000000004309 211.0
REGS2_k127_8148229_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 580.0
REGS2_k127_8148229_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000002652 223.0
REGS2_k127_8148229_2 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000002223 217.0
REGS2_k127_8148229_3 DNA methylase K00590 - 2.1.1.113 0.00000000000002583 83.0
REGS2_k127_8159749_0 Peptidase family M28 - - - 1.422e-205 655.0
REGS2_k127_8159749_1 Peptidase family M1 domain - - - 3.781e-196 631.0
REGS2_k127_8159749_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
REGS2_k127_8159749_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.00000000000000000000000000000000000000000000000000000000000002016 224.0
REGS2_k127_8159749_12 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000002841 219.0
REGS2_k127_8159749_13 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.00000000000000000000000000000000000000000000000000000000005107 211.0
REGS2_k127_8159749_14 TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000002812 186.0
REGS2_k127_8159749_15 - - - - 0.00000000000000000000000000000000000003159 159.0
REGS2_k127_8159749_16 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000001292 143.0
REGS2_k127_8159749_17 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000006114 141.0
REGS2_k127_8159749_18 Cytochrome C biogenesis protein - - - 0.000000000000000000000002501 111.0
REGS2_k127_8159749_19 ABC-2 family transporter protein - - - 0.0000000000000000000001517 108.0
REGS2_k127_8159749_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 549.0
REGS2_k127_8159749_20 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000008343 94.0
REGS2_k127_8159749_21 Protein of unknown function (DUF4876) - - - 0.000000000000002245 89.0
REGS2_k127_8159749_22 EamA-like transporter family - - - 0.000000000007097 79.0
REGS2_k127_8159749_23 Protein of unknown function (DUF1569) - - - 0.000000001414 66.0
REGS2_k127_8159749_26 Dienelactone hydrolase family - - - 0.00004676 55.0
REGS2_k127_8159749_3 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 457.0
REGS2_k127_8159749_4 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 376.0
REGS2_k127_8159749_5 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 306.0
REGS2_k127_8159749_6 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 310.0
REGS2_k127_8159749_7 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
REGS2_k127_8159749_8 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002035 284.0
REGS2_k127_8159749_9 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
REGS2_k127_8206569_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 508.0
REGS2_k127_8206569_1 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002312 287.0
REGS2_k127_8206569_2 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567,K10778 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000000000000000000006868 188.0
REGS2_k127_8206569_3 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000002879 136.0
REGS2_k127_8206569_5 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000009724 121.0
REGS2_k127_8206569_6 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000002705 116.0
REGS2_k127_8206569_9 Cytochrome c - - - 0.000000004862 69.0
REGS2_k127_8230629_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000514 92.0
REGS2_k127_8288779_0 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 525.0
REGS2_k127_8288779_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 494.0
REGS2_k127_8288779_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001576 281.0
REGS2_k127_8288779_3 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 253.0
REGS2_k127_8288779_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000003346 119.0
REGS2_k127_8511716_0 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 1.008e-295 947.0
REGS2_k127_8511716_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 6.507e-246 774.0
REGS2_k127_8511716_2 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 374.0
REGS2_k127_8511716_3 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000009308 234.0
REGS2_k127_8511716_4 YGGT family K02221 - - 0.000000000000000000000000000000000003301 146.0
REGS2_k127_8511716_5 DUF167 K09131 - - 0.0000000000000003576 89.0
REGS2_k127_8511716_6 ECF sigma factor - - - 0.000006324 55.0
REGS2_k127_8511716_7 enterobactin catabolic process - - - 0.000703 42.0
REGS2_k127_867295_0 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 507.0
REGS2_k127_867295_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 469.0
REGS2_k127_867295_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 302.0
REGS2_k127_867295_3 - - - - 0.0000000000000000468 89.0
REGS2_k127_867295_4 PHP domain K07053 - 3.1.3.97 0.000002205 50.0
REGS2_k127_875518_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1032.0
REGS2_k127_875518_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.482e-233 745.0
REGS2_k127_875518_10 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 482.0
REGS2_k127_875518_11 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 482.0
REGS2_k127_875518_12 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 490.0
REGS2_k127_875518_13 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 484.0
REGS2_k127_875518_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 476.0
REGS2_k127_875518_15 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 471.0
REGS2_k127_875518_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 468.0
REGS2_k127_875518_17 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 430.0
REGS2_k127_875518_18 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 414.0
REGS2_k127_875518_19 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 384.0
REGS2_k127_875518_2 Domain of unknown function (DUF5117) - - - 7.128e-220 719.0
REGS2_k127_875518_20 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 376.0
REGS2_k127_875518_21 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 368.0
REGS2_k127_875518_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 382.0
REGS2_k127_875518_23 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 323.0
REGS2_k127_875518_24 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 307.0
REGS2_k127_875518_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 293.0
REGS2_k127_875518_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003429 280.0
REGS2_k127_875518_27 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000002846 286.0
REGS2_k127_875518_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005229 259.0
REGS2_k127_875518_29 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009049 271.0
REGS2_k127_875518_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.826e-198 629.0
REGS2_k127_875518_30 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003806 256.0
REGS2_k127_875518_31 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001044 248.0
REGS2_k127_875518_32 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000008277 239.0
REGS2_k127_875518_33 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.00000000000000000000000000000000000000000000000000000000000009426 226.0
REGS2_k127_875518_34 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000000005429 221.0
REGS2_k127_875518_35 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000005283 202.0
REGS2_k127_875518_36 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000001441 197.0
REGS2_k127_875518_37 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000004981 175.0
REGS2_k127_875518_38 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000000000000000000001808 169.0
REGS2_k127_875518_39 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000002775 157.0
REGS2_k127_875518_4 Nicastrin K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 638.0
REGS2_k127_875518_40 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000007803 157.0
REGS2_k127_875518_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000799 145.0
REGS2_k127_875518_42 Uncharacterised protein family (UPF0182) K09118 - - 0.00000000000000000000000000000000001352 157.0
REGS2_k127_875518_43 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000005757 142.0
REGS2_k127_875518_44 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000696 141.0
REGS2_k127_875518_45 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000004713 134.0
REGS2_k127_875518_46 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000005106 125.0
REGS2_k127_875518_47 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000563 125.0
REGS2_k127_875518_48 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000002101 119.0
REGS2_k127_875518_49 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000009947 81.0
REGS2_k127_875518_5 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 582.0
REGS2_k127_875518_50 Phosphopantetheine attachment site K02078 - - 0.0000000000000001177 80.0
REGS2_k127_875518_51 Preprotein translocase SecG subunit K03075 - - 0.000000000000004637 88.0
REGS2_k127_875518_52 ThiS family K03636 - - 0.000000000007603 71.0
REGS2_k127_875518_53 - - - - 0.0006535 52.0
REGS2_k127_875518_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 553.0
REGS2_k127_875518_7 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 529.0
REGS2_k127_875518_8 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 489.0
REGS2_k127_875518_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 491.0
REGS2_k127_885745_0 Large extracellular alpha-helical protein K06894 - - 3.232e-315 995.0
REGS2_k127_885745_1 cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 302.0
REGS2_k127_885745_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002285 233.0
REGS2_k127_885745_3 AIPR protein - - - 0.00000000000000000000000000000000000000000000000378 178.0
REGS2_k127_886138_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 9.692e-255 796.0
REGS2_k127_886138_1 Belongs to the carbamoyltransferase HypF family K04656 - - 3.294e-220 716.0
REGS2_k127_886138_10 E1-E2 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 452.0
REGS2_k127_886138_11 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 389.0
REGS2_k127_886138_12 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 319.0
REGS2_k127_886138_13 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 325.0
REGS2_k127_886138_14 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421 284.0
REGS2_k127_886138_15 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001766 280.0
REGS2_k127_886138_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001722 250.0
REGS2_k127_886138_17 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000006331 223.0
REGS2_k127_886138_18 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000005822 229.0
REGS2_k127_886138_19 Cytochrome b/b6/petB K00412 - - 0.0000000000000000000000000000000000000000000000000000000738 212.0
REGS2_k127_886138_2 aconitate hydratase K01681 - 4.2.1.3 3.68e-219 687.0
REGS2_k127_886138_20 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000428 214.0
REGS2_k127_886138_21 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001461 209.0
REGS2_k127_886138_22 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000002564 190.0
REGS2_k127_886138_23 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000006575 189.0
REGS2_k127_886138_24 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000001742 182.0
REGS2_k127_886138_25 - - - - 0.000000000000000000000000000000000000007222 150.0
REGS2_k127_886138_26 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000002931 144.0
REGS2_k127_886138_27 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000001861 123.0
REGS2_k127_886138_28 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000003573 121.0
REGS2_k127_886138_29 - - - - 0.000000000000000000000003594 108.0
REGS2_k127_886138_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 9.213e-204 654.0
REGS2_k127_886138_30 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000006347 116.0
REGS2_k127_886138_31 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000001898 105.0
REGS2_k127_886138_32 - - - - 0.0000000000000000001019 98.0
REGS2_k127_886138_33 Formyl transferase K11175 - 2.1.2.2 0.00000000000006313 82.0
REGS2_k127_886138_34 Universal stress protein - - - 0.000000000005438 77.0
REGS2_k127_886138_35 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000001234 75.0
REGS2_k127_886138_36 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000006051 75.0
REGS2_k127_886138_37 Belongs to the universal stress protein A family - - - 0.000000002332 68.0
REGS2_k127_886138_38 Domain of unknown function (DUF4386) - - - 0.000000004354 64.0
REGS2_k127_886138_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000009115 67.0
REGS2_k127_886138_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 601.0
REGS2_k127_886138_40 - - - - 0.00000003956 66.0
REGS2_k127_886138_41 PFAM iron dependent repressor K03709 - - 0.0000005482 58.0
REGS2_k127_886138_42 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000005085 57.0
REGS2_k127_886138_43 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000008518 51.0
REGS2_k127_886138_44 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00008272 52.0
REGS2_k127_886138_45 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0001404 53.0
REGS2_k127_886138_46 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0002529 53.0
REGS2_k127_886138_47 Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions K02636 - 1.10.9.1 0.0004352 49.0
REGS2_k127_886138_48 Protein of unknown function (DUF2892) - - - 0.0009642 46.0
REGS2_k127_886138_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 554.0
REGS2_k127_886138_6 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 522.0
REGS2_k127_886138_7 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 488.0
REGS2_k127_886138_8 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 460.0
REGS2_k127_886138_9 Small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 438.0
REGS2_k127_929606_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 545.0
REGS2_k127_929606_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 567.0
REGS2_k127_929606_10 Transcriptional regulatory protein, C terminal - - - 0.0003014 47.0
REGS2_k127_929606_2 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 439.0
REGS2_k127_929606_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000001687 207.0
REGS2_k127_929606_4 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000007212 198.0
REGS2_k127_929606_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000003149 189.0
REGS2_k127_929606_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000007052 184.0
REGS2_k127_929606_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000002236 146.0
REGS2_k127_929606_8 PFAM response regulator receiver - - - 0.00000000000000000000000000000000005338 139.0
REGS2_k127_929606_9 SNARE associated Golgi protein - - - 0.000000000000000000000000000001841 129.0
REGS2_k127_953424_0 Sortilin, neurotensin receptor 3, - - - 0.0 1198.0
REGS2_k127_953424_1 4Fe-4S dicluster domain K00184 - - 3.61e-237 766.0
REGS2_k127_953424_10 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000002329 201.0
REGS2_k127_953424_11 GHMP kinase K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000175 195.0
REGS2_k127_953424_12 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000003805 190.0
REGS2_k127_953424_13 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000006706 144.0
REGS2_k127_953424_14 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000003128 142.0
REGS2_k127_953424_15 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000833 149.0
REGS2_k127_953424_16 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000003485 106.0
REGS2_k127_953424_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000005403 99.0
REGS2_k127_953424_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 519.0
REGS2_k127_953424_3 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 507.0
REGS2_k127_953424_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 337.0
REGS2_k127_953424_5 dihydroorotate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 331.0
REGS2_k127_953424_6 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 310.0
REGS2_k127_953424_7 Belongs to the mandelate racemase muconate lactonizing enzyme family K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000001351 258.0
REGS2_k127_953424_8 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001494 226.0
REGS2_k127_953424_9 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000005294 213.0
REGS2_k127_983209_0 PFAM CHASE2 domain - - - 0.0000000000000000000000000000000000000005587 151.0
REGS2_k127_996773_0 transmembrane transporter activity K03296 - - 0.0 1345.0
REGS2_k127_996773_1 GMC oxidoreductase - - - 5.593e-272 848.0
REGS2_k127_996773_10 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 346.0
REGS2_k127_996773_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 329.0
REGS2_k127_996773_12 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 328.0
REGS2_k127_996773_13 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004691 291.0
REGS2_k127_996773_14 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001616 265.0
REGS2_k127_996773_15 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 255.0
REGS2_k127_996773_16 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000002053 233.0
REGS2_k127_996773_17 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000003094 233.0
REGS2_k127_996773_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000001057 213.0
REGS2_k127_996773_19 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000000000002582 200.0
REGS2_k127_996773_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 9.92e-204 640.0
REGS2_k127_996773_20 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000001079 184.0
REGS2_k127_996773_21 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000003305 139.0
REGS2_k127_996773_22 Cysteine-rich CPXCG - - - 0.0000000000000000000000003405 108.0
REGS2_k127_996773_23 peptidyl-tyrosine sulfation - - - 0.000000000000000001976 100.0
REGS2_k127_996773_25 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000001463 86.0
REGS2_k127_996773_26 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000008883 68.0
REGS2_k127_996773_27 domain, Protein - - - 0.00000001584 60.0
REGS2_k127_996773_28 Membrane - - - 0.000007172 58.0
REGS2_k127_996773_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 580.0
REGS2_k127_996773_4 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 514.0
REGS2_k127_996773_5 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 417.0
REGS2_k127_996773_6 Protein of unknown function (DUF445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 398.0
REGS2_k127_996773_7 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 380.0
REGS2_k127_996773_8 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 389.0
REGS2_k127_996773_9 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 359.0