Overview

ID MAG03333
Name REGS2_bin.22
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family CSP1-6
Genus AR19
Species
Assembly information
Completeness (%) 75.11
Contamination (%) 1.18
GC content (%) 71.0
N50 (bp) 30,637
Genome size (bp) 3,234,088

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2991

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1037703_0 GMC oxidoreductase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 2.998e-226 714.0
REGS2_k127_1037703_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.976e-209 667.0
REGS2_k127_1037703_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 466.0
REGS2_k127_1037703_3 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 451.0
REGS2_k127_1037703_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 374.0
REGS2_k127_1037703_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003393 281.0
REGS2_k127_1037703_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000001947 226.0
REGS2_k127_1084464_0 metallopeptidase activity K03592 - - 5.499e-201 642.0
REGS2_k127_1084464_1 Putative modulator of DNA gyrase K03568 - - 1.511e-197 629.0
REGS2_k127_1084464_10 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000001913 168.0
REGS2_k127_1084464_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000001286 156.0
REGS2_k127_1084464_12 Rieske [2Fe-2S] domain - - - 0.0000000000000000000001867 100.0
REGS2_k127_1084464_13 Predicted membrane protein (DUF2079) - - - 0.0000000000000000005233 102.0
REGS2_k127_1084464_2 molybdopterin K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 355.0
REGS2_k127_1084464_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 332.0
REGS2_k127_1084464_4 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 331.0
REGS2_k127_1084464_5 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 318.0
REGS2_k127_1084464_6 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 303.0
REGS2_k127_1084464_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001747 293.0
REGS2_k127_1084464_8 domain protein K01992,K06994 - - 0.0000000000000000000000000000000000000000000000000000000000008287 220.0
REGS2_k127_1084464_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000001831 196.0
REGS2_k127_1088561_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1104.0
REGS2_k127_1088561_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 610.0
REGS2_k127_1088561_10 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 359.0
REGS2_k127_1088561_11 Peptidase dimerisation domain K21613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 336.0
REGS2_k127_1088561_12 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 328.0
REGS2_k127_1088561_13 amidohydrolase K21613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 329.0
REGS2_k127_1088561_14 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 325.0
REGS2_k127_1088561_15 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 297.0
REGS2_k127_1088561_16 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003344 282.0
REGS2_k127_1088561_17 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
REGS2_k127_1088561_18 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
REGS2_k127_1088561_19 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 263.0
REGS2_k127_1088561_2 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 544.0
REGS2_k127_1088561_20 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009559 241.0
REGS2_k127_1088561_21 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007488 267.0
REGS2_k127_1088561_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000001929 224.0
REGS2_k127_1088561_23 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000001319 217.0
REGS2_k127_1088561_24 dihydroorotate dehydrogenase activity K02823,K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000002271 198.0
REGS2_k127_1088561_25 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000358 192.0
REGS2_k127_1088561_26 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000949 197.0
REGS2_k127_1088561_27 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000005348 177.0
REGS2_k127_1088561_28 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000009207 171.0
REGS2_k127_1088561_29 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000002837 157.0
REGS2_k127_1088561_3 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 530.0
REGS2_k127_1088561_30 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000000000000000000000001613 158.0
REGS2_k127_1088561_31 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000002498 151.0
REGS2_k127_1088561_32 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000003345 149.0
REGS2_k127_1088561_33 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000001015 131.0
REGS2_k127_1088561_34 MlaC protein K07323 - - 0.0000000000000000000000000000001378 136.0
REGS2_k127_1088561_35 belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000375 117.0
REGS2_k127_1088561_36 - - - - 0.0000000000000000000003352 109.0
REGS2_k127_1088561_37 Cupin domain - - - 0.0000000000000000001977 93.0
REGS2_k127_1088561_38 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02490 - - 0.0000000000000000218 96.0
REGS2_k127_1088561_39 Protein of unknown function (DUF3047) - - - 0.000005058 57.0
REGS2_k127_1088561_4 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 447.0
REGS2_k127_1088561_40 PFAM Cytochrome C - - - 0.0007461 50.0
REGS2_k127_1088561_5 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 385.0
REGS2_k127_1088561_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 364.0
REGS2_k127_1088561_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 367.0
REGS2_k127_1088561_8 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 376.0
REGS2_k127_1088561_9 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 351.0
REGS2_k127_1232521_0 UPF0313 protein - - - 0.0 1085.0
REGS2_k127_1232521_1 Belongs to the CinA family - - - 1.638e-207 656.0
REGS2_k127_1232521_10 Antibiotic biosynthesis monooxygenase - - - 0.000000000001678 72.0
REGS2_k127_1232521_11 Thioesterase-like superfamily K07107 - - 0.00000003783 62.0
REGS2_k127_1232521_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 445.0
REGS2_k127_1232521_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 364.0
REGS2_k127_1232521_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 334.0
REGS2_k127_1232521_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 337.0
REGS2_k127_1232521_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004877 255.0
REGS2_k127_1232521_7 Sugar (and other) transporter K08161 - - 0.0000000000000000000000000000000000000008497 167.0
REGS2_k127_1232521_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000001449 139.0
REGS2_k127_1232521_9 Dehydrogenase K00101 - 1.1.2.3 0.0000000000008865 73.0
REGS2_k127_1425303_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 512.0
REGS2_k127_1425303_1 PFAM Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 382.0
REGS2_k127_1425303_10 - - - - 0.00000002811 63.0
REGS2_k127_1425303_11 Alcohol dehydrogenase GroES domain protein K00001 - 1.1.1.1 0.0000004663 51.0
REGS2_k127_1425303_12 Alkylmercury lyase K00221 - 4.99.1.2 0.00009946 53.0
REGS2_k127_1425303_13 - - - - 0.0007876 47.0
REGS2_k127_1425303_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 317.0
REGS2_k127_1425303_3 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 307.0
REGS2_k127_1425303_4 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000001659 156.0
REGS2_k127_1425303_5 - - - - 0.00000000000000000000000000000007501 126.0
REGS2_k127_1425303_6 - - - - 0.00000000000000000107 94.0
REGS2_k127_1425303_7 - - - - 0.000000000000005213 85.0
REGS2_k127_1425303_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000657 64.0
REGS2_k127_1429263_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 427.0
REGS2_k127_1429263_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008675 278.0
REGS2_k127_1429263_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001332 262.0
REGS2_k127_1429263_3 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000006302 213.0
REGS2_k127_1560773_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 565.0
REGS2_k127_1560773_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 512.0
REGS2_k127_1560773_2 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 475.0
REGS2_k127_1560773_3 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
REGS2_k127_1560773_4 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002209 250.0
REGS2_k127_1560773_5 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000007646 252.0
REGS2_k127_1560773_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000468 224.0
REGS2_k127_1560773_7 leucine import across plasma membrane K01997,K01999 - - 0.00000000002128 65.0
REGS2_k127_1560773_8 Creatinase/Prolidase N-terminal domain K15783 - 3.5.4.44 0.0003425 52.0
REGS2_k127_1598694_0 Belongs to the IlvD Edd family - - - 1.696e-229 725.0
REGS2_k127_1598694_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.897e-219 689.0
REGS2_k127_1598694_10 PFAM 6-phosphogluconate dehydrogenase NAD-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 318.0
REGS2_k127_1598694_11 Carbon-nitrogen hydrolase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 306.0
REGS2_k127_1598694_12 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 304.0
REGS2_k127_1598694_13 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 296.0
REGS2_k127_1598694_14 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000006261 273.0
REGS2_k127_1598694_15 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003386 269.0
REGS2_k127_1598694_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001784 241.0
REGS2_k127_1598694_17 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000001591 211.0
REGS2_k127_1598694_18 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000007143 213.0
REGS2_k127_1598694_19 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000007968 203.0
REGS2_k127_1598694_2 acyl-CoA dehydrogenase K09456,K20035 - - 1.095e-198 636.0
REGS2_k127_1598694_20 Formate hydrogenlyase K12136,K15827 - - 0.00000000000000000000000000000000000000000000000000002054 192.0
REGS2_k127_1598694_21 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000001166 179.0
REGS2_k127_1598694_22 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000004745 169.0
REGS2_k127_1598694_23 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000001307 171.0
REGS2_k127_1598694_24 NUDIX domain - - - 0.00000000000000000000000000000000000004963 147.0
REGS2_k127_1598694_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000000001794 128.0
REGS2_k127_1598694_26 GYD domain - - - 0.0000000000000000000000000000188 121.0
REGS2_k127_1598694_27 Permeases of the drug metabolite transporter (DMT) superfamily K03298 - - 0.00000000000000000000000002021 120.0
REGS2_k127_1598694_28 - - - - 0.0000000000000001225 83.0
REGS2_k127_1598694_29 - - - - 0.00000000000001378 80.0
REGS2_k127_1598694_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 562.0
REGS2_k127_1598694_30 Domain of unknown function (DUF4926) - - - 0.00000000000007946 79.0
REGS2_k127_1598694_31 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07156 - - 0.0000000000009278 81.0
REGS2_k127_1598694_32 - - - - 0.00000005125 57.0
REGS2_k127_1598694_33 - - - - 0.000007875 59.0
REGS2_k127_1598694_4 Protein of unknown function (DUF993) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 532.0
REGS2_k127_1598694_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 478.0
REGS2_k127_1598694_6 FGGY family of carbohydrate kinases, C-terminal domain K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 458.0
REGS2_k127_1598694_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 450.0
REGS2_k127_1598694_8 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 384.0
REGS2_k127_1598694_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 350.0
REGS2_k127_169423_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 345.0
REGS2_k127_169423_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 340.0
REGS2_k127_169423_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 346.0
REGS2_k127_169423_3 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 313.0
REGS2_k127_169423_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
REGS2_k127_169423_5 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000001179 250.0
REGS2_k127_169423_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000002867 190.0
REGS2_k127_169423_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000003528 195.0
REGS2_k127_1726829_0 xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 567.0
REGS2_k127_1726829_1 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 372.0
REGS2_k127_1726829_10 helix_turn_helix isocitrate lyase regulation K13641 - - 0.00000000000000000000000000000000001553 146.0
REGS2_k127_1726829_11 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000482 153.0
REGS2_k127_1726829_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 305.0
REGS2_k127_1726829_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 302.0
REGS2_k127_1726829_4 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 295.0
REGS2_k127_1726829_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005027 280.0
REGS2_k127_1726829_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000006822 202.0
REGS2_k127_1726829_7 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001673 209.0
REGS2_k127_1726829_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000006479 204.0
REGS2_k127_1726829_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000004905 159.0
REGS2_k127_1742984_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
REGS2_k127_1742984_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 460.0
REGS2_k127_1742984_10 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000002506 227.0
REGS2_k127_1742984_11 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000003032 229.0
REGS2_k127_1742984_12 - - - - 0.000000000000000000000000000000000000000000000000000001158 203.0
REGS2_k127_1742984_13 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000009007 187.0
REGS2_k127_1742984_14 Tim44 - - - 0.000000000000000000000000000000000000000000000000002545 194.0
REGS2_k127_1742984_15 Hydrolase - - - 0.0000000000000000000000000000000000000000001061 170.0
REGS2_k127_1742984_16 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000201 115.0
REGS2_k127_1742984_17 glycosyl transferase family 2 K20444 - - 0.00000000000000000000002414 110.0
REGS2_k127_1742984_18 AsmA-like C-terminal region K07289 - - 0.0000000000001089 84.0
REGS2_k127_1742984_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 456.0
REGS2_k127_1742984_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 402.0
REGS2_k127_1742984_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 408.0
REGS2_k127_1742984_5 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 353.0
REGS2_k127_1742984_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 341.0
REGS2_k127_1742984_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 312.0
REGS2_k127_1742984_8 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 315.0
REGS2_k127_1742984_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001262 254.0
REGS2_k127_1749184_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 554.0
REGS2_k127_1749184_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 362.0
REGS2_k127_1749184_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 346.0
REGS2_k127_1749184_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 314.0
REGS2_k127_1749184_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000374 201.0
REGS2_k127_1749184_5 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000005184 191.0
REGS2_k127_1749184_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000001108 141.0
REGS2_k127_1749184_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000364 129.0
REGS2_k127_1749184_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000004275 70.0
REGS2_k127_1749184_9 Domain of unknown function (DUF4115) K15539 - - 0.0000000005485 61.0
REGS2_k127_1785046_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1138.0
REGS2_k127_1785046_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1131.0
REGS2_k127_1785046_10 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 507.0
REGS2_k127_1785046_11 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 448.0
REGS2_k127_1785046_12 PFAM Sodium sulphate symporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 414.0
REGS2_k127_1785046_13 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 398.0
REGS2_k127_1785046_14 quinone binding K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 385.0
REGS2_k127_1785046_15 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 366.0
REGS2_k127_1785046_16 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 338.0
REGS2_k127_1785046_17 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 344.0
REGS2_k127_1785046_18 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 339.0
REGS2_k127_1785046_19 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 312.0
REGS2_k127_1785046_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.463e-287 906.0
REGS2_k127_1785046_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 317.0
REGS2_k127_1785046_21 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 303.0
REGS2_k127_1785046_22 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 290.0
REGS2_k127_1785046_23 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003465 286.0
REGS2_k127_1785046_24 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001048 277.0
REGS2_k127_1785046_25 vacuolar iron transporter - GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015318,GO:0016020,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030026,GO:0031090,GO:0034220,GO:0034755,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055071,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0097577,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098805 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004631 282.0
REGS2_k127_1785046_26 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001016 288.0
REGS2_k127_1785046_27 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005398 271.0
REGS2_k127_1785046_28 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002208 269.0
REGS2_k127_1785046_29 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000331 264.0
REGS2_k127_1785046_3 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 2.908e-267 859.0
REGS2_k127_1785046_30 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003981 265.0
REGS2_k127_1785046_31 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000005987 246.0
REGS2_k127_1785046_32 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001341 256.0
REGS2_k127_1785046_33 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000001211 237.0
REGS2_k127_1785046_34 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000008529 233.0
REGS2_k127_1785046_35 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000001055 223.0
REGS2_k127_1785046_36 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000003618 233.0
REGS2_k127_1785046_37 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000007574 213.0
REGS2_k127_1785046_38 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000003559 209.0
REGS2_k127_1785046_39 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000004762 199.0
REGS2_k127_1785046_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 3.638e-226 731.0
REGS2_k127_1785046_40 - - - - 0.000000000000000000000000000000000000000000000000002586 188.0
REGS2_k127_1785046_41 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000003211 188.0
REGS2_k127_1785046_42 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000009907 193.0
REGS2_k127_1785046_43 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000000000001757 188.0
REGS2_k127_1785046_44 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000001894 182.0
REGS2_k127_1785046_45 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000215 172.0
REGS2_k127_1785046_46 Pas domain - - - 0.00000000000000000000000000000000000000000007914 168.0
REGS2_k127_1785046_47 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000000004473 161.0
REGS2_k127_1785046_48 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000003777 167.0
REGS2_k127_1785046_49 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000007113 155.0
REGS2_k127_1785046_5 Domain of unknown function (DUF4070) - - - 2.412e-222 707.0
REGS2_k127_1785046_50 Domain in cystathionine beta-synthase and other proteins. K04767 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000008228 170.0
REGS2_k127_1785046_51 adenylylsulfate kinase activity K00860 - 2.7.1.25 0.000000000000000000000000000000000000001055 166.0
REGS2_k127_1785046_52 Sulphur transport K07112 - - 0.0000000000000000000000000000000000001594 147.0
REGS2_k127_1785046_53 conserved protein (DUF2249) - - - 0.00000000000000000000000000000000000448 147.0
REGS2_k127_1785046_54 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000008648 149.0
REGS2_k127_1785046_55 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000000003394 138.0
REGS2_k127_1785046_56 PFAM CBS domain K04767 - - 0.000000000000000000000000000000001932 134.0
REGS2_k127_1785046_57 membrane transporter protein K07090 - - 0.0000000000000000000000000002106 119.0
REGS2_k127_1785046_58 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000002519 121.0
REGS2_k127_1785046_59 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.0000000000000000000000000005984 125.0
REGS2_k127_1785046_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.789e-202 642.0
REGS2_k127_1785046_60 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.000000000000000000000000003695 119.0
REGS2_k127_1785046_61 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000439 115.0
REGS2_k127_1785046_62 Acetoin utilization protein AcuB K04767 - - 0.000000000000000000000004823 107.0
REGS2_k127_1785046_63 Acetyltransferase (GNAT) family - - - 0.00000000000000000000002831 106.0
REGS2_k127_1785046_64 PFAM UspA domain protein - - - 0.0000000000000000000002903 104.0
REGS2_k127_1785046_65 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000005775 106.0
REGS2_k127_1785046_66 Universal stress protein - - - 0.00000000000000000001138 97.0
REGS2_k127_1785046_67 Universal stress protein - - - 0.0000000000000000002042 95.0
REGS2_k127_1785046_68 Universal stress protein family - - - 0.0000000000000000004774 94.0
REGS2_k127_1785046_69 Sulphur transport K07112 - - 0.000000000000000002754 94.0
REGS2_k127_1785046_7 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 558.0
REGS2_k127_1785046_70 - - - - 0.000000000000000004077 89.0
REGS2_k127_1785046_71 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000001116 97.0
REGS2_k127_1785046_72 Universal stress protein - - - 0.0000000000000002328 89.0
REGS2_k127_1785046_73 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000002814 84.0
REGS2_k127_1785046_74 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000007751 85.0
REGS2_k127_1785046_75 response regulator K02667 - - 0.0000000000000008131 87.0
REGS2_k127_1785046_76 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000001422 84.0
REGS2_k127_1785046_77 Peptidase family M28 - - - 0.0000000000002099 81.0
REGS2_k127_1785046_78 Sulphur transport K07112 - - 0.0000000002398 64.0
REGS2_k127_1785046_79 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000005333 68.0
REGS2_k127_1785046_8 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 534.0
REGS2_k127_1785046_80 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000000209 61.0
REGS2_k127_1785046_81 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00005036 45.0
REGS2_k127_1785046_82 Tetratricopeptide repeat - - - 0.00006442 54.0
REGS2_k127_1785046_83 Belongs to the universal stress protein A family K06149 - - 0.0000733 53.0
REGS2_k127_1785046_84 - - - - 0.0003006 46.0
REGS2_k127_1785046_9 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 515.0
REGS2_k127_1877114_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 411.0
REGS2_k127_1877114_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 383.0
REGS2_k127_1877114_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000306 168.0
REGS2_k127_1877114_3 Methyltransferase domain K19620 - - 0.00000000000000000000000000001164 136.0
REGS2_k127_1881787_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 352.0
REGS2_k127_1881787_1 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.000000000000000000000000000000000000000000000000000000000000002723 244.0
REGS2_k127_1881787_2 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000001398 137.0
REGS2_k127_1881787_3 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000002005 119.0
REGS2_k127_1881787_4 ArsC family - - - 0.000000000000000000000000001343 119.0
REGS2_k127_1881787_5 Protein of unknown function (DUF2442) - - - 0.0000000000000000009435 88.0
REGS2_k127_1881787_6 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00001903 49.0
REGS2_k127_1904896_0 FtsX-like permease family K02004 - - 1.127e-207 674.0
REGS2_k127_1904896_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 628.0
REGS2_k127_1904896_10 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000001064 188.0
REGS2_k127_1904896_11 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000005571 189.0
REGS2_k127_1904896_12 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000009063 176.0
REGS2_k127_1904896_13 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000002705 141.0
REGS2_k127_1904896_14 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000002687 137.0
REGS2_k127_1904896_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000848 156.0
REGS2_k127_1904896_16 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000000003731 131.0
REGS2_k127_1904896_17 - - - - 0.0000000000000000000000116 108.0
REGS2_k127_1904896_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000002115 114.0
REGS2_k127_1904896_19 Peptidase family M48 - - - 0.000008122 57.0
REGS2_k127_1904896_2 N-6 DNA Methylase K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 567.0
REGS2_k127_1904896_3 Zinc finger, swim domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 554.0
REGS2_k127_1904896_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 396.0
REGS2_k127_1904896_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 353.0
REGS2_k127_1904896_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 296.0
REGS2_k127_1904896_7 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002 258.0
REGS2_k127_1904896_8 PFAM luciferase-like K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000005585 247.0
REGS2_k127_1904896_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000001649 225.0
REGS2_k127_1924349_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.448e-223 723.0
REGS2_k127_1924349_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 510.0
REGS2_k127_1924349_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K16079,K22110 - - 0.00000002589 64.0
REGS2_k127_1924349_11 - - - - 0.00001196 50.0
REGS2_k127_1924349_13 Belongs to the 'phage' integrase family - - - 0.0006341 44.0
REGS2_k127_1924349_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
REGS2_k127_1924349_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000006038 226.0
REGS2_k127_1924349_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000001158 166.0
REGS2_k127_1924349_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000002534 113.0
REGS2_k127_1924349_6 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000528 103.0
REGS2_k127_1924349_7 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000702 99.0
REGS2_k127_1924349_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000001248 104.0
REGS2_k127_1924349_9 - - - - 0.000000000000000000108 91.0
REGS2_k127_1924584_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1735.0
REGS2_k127_1924584_1 NAD synthase K01916 - 6.3.1.5 1.323e-198 654.0
REGS2_k127_1924584_10 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000001226 150.0
REGS2_k127_1924584_11 Flavin reductase like domain - - - 0.00000000000000000000000000000000003969 153.0
REGS2_k127_1924584_12 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000002645 104.0
REGS2_k127_1924584_13 Amidohydrolase - - - 0.0000000001624 67.0
REGS2_k127_1924584_14 Tripartite tricarboxylate transporter family receptor - - - 0.00005047 47.0
REGS2_k127_1924584_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 515.0
REGS2_k127_1924584_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 444.0
REGS2_k127_1924584_4 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 396.0
REGS2_k127_1924584_5 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 405.0
REGS2_k127_1924584_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 355.0
REGS2_k127_1924584_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 304.0
REGS2_k127_1924584_8 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000002139 247.0
REGS2_k127_1924584_9 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000001455 163.0
REGS2_k127_1924729_0 GlcNAc-PI de-N-acetylase - - - 4.38e-266 844.0
REGS2_k127_1924729_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 337.0
REGS2_k127_1924729_2 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000005296 213.0
REGS2_k127_1924729_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000001099 70.0
REGS2_k127_1965615_0 Bacterial DNA polymerase III alpha subunit - - - 7.265e-289 924.0
REGS2_k127_1965615_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 325.0
REGS2_k127_1965615_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000001908 78.0
REGS2_k127_1968506_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.313e-283 900.0
REGS2_k127_1968506_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 308.0
REGS2_k127_1968506_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001759 298.0
REGS2_k127_1968506_3 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000001712 225.0
REGS2_k127_1968506_4 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000004303 228.0
REGS2_k127_1968506_5 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000633 144.0
REGS2_k127_1968506_6 Methyltransferase domain - - - 0.0000000000000000000000000009213 131.0
REGS2_k127_1968506_7 response regulator - - - 0.0000000000000000000002331 114.0
REGS2_k127_1998672_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000836 625.0
REGS2_k127_1998672_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 514.0
REGS2_k127_1998672_2 Belongs to the binding-protein-dependent transport system permease family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 295.0
REGS2_k127_1998672_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006697 259.0
REGS2_k127_1998672_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000008615 178.0
REGS2_k127_2000421_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 582.0
REGS2_k127_2000421_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 396.0
REGS2_k127_2000421_2 extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 333.0
REGS2_k127_2000421_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 294.0
REGS2_k127_2000421_4 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 293.0
REGS2_k127_2000421_5 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007645 274.0
REGS2_k127_2000421_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000787 271.0
REGS2_k127_2000421_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003039 261.0
REGS2_k127_2000421_8 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000004612 175.0
REGS2_k127_2000421_9 Tripartite tricarboxylate transporter TctB family - - - 0.0000001528 65.0
REGS2_k127_2000454_0 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 525.0
REGS2_k127_2000454_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 466.0
REGS2_k127_2000454_10 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 317.0
REGS2_k127_2000454_11 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 308.0
REGS2_k127_2000454_12 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001622 289.0
REGS2_k127_2000454_13 Acyl-CoA dehydrogenase, C-terminal domain K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005927 280.0
REGS2_k127_2000454_14 transport system periplasmic component K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000007392 238.0
REGS2_k127_2000454_15 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000008089 228.0
REGS2_k127_2000454_16 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000328 228.0
REGS2_k127_2000454_17 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001063 231.0
REGS2_k127_2000454_18 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002753 222.0
REGS2_k127_2000454_19 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000003201 226.0
REGS2_k127_2000454_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 458.0
REGS2_k127_2000454_20 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
REGS2_k127_2000454_21 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000009866 216.0
REGS2_k127_2000454_22 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000005808 175.0
REGS2_k127_2000454_23 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000001294 166.0
REGS2_k127_2000454_24 Nitroreductase - - - 0.0000000000000000000000000000000002393 141.0
REGS2_k127_2000454_3 TRAP transporter, 4TM 12TM fusion protein' - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 431.0
REGS2_k127_2000454_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 406.0
REGS2_k127_2000454_5 Acyl-CoA dehydrogenase, N-terminal domain K18244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 377.0
REGS2_k127_2000454_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 349.0
REGS2_k127_2000454_7 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 342.0
REGS2_k127_2000454_8 Coenzyme A transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 321.0
REGS2_k127_2000454_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 310.0
REGS2_k127_2034469_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 9.248e-241 771.0
REGS2_k127_2034469_1 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 2.66e-196 626.0
REGS2_k127_2034469_10 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 310.0
REGS2_k127_2034469_11 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
REGS2_k127_2034469_12 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001097 305.0
REGS2_k127_2034469_13 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
REGS2_k127_2034469_14 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
REGS2_k127_2034469_15 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000004362 265.0
REGS2_k127_2034469_16 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007239 257.0
REGS2_k127_2034469_17 Receptor family ligand binding region family protein 22 K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003148 269.0
REGS2_k127_2034469_18 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001731 255.0
REGS2_k127_2034469_19 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008708 258.0
REGS2_k127_2034469_2 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 567.0
REGS2_k127_2034469_20 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000374 265.0
REGS2_k127_2034469_21 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001972 250.0
REGS2_k127_2034469_22 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
REGS2_k127_2034469_23 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000005261 249.0
REGS2_k127_2034469_24 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00179,K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000004352 199.0
REGS2_k127_2034469_25 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000000004909 214.0
REGS2_k127_2034469_26 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000001 190.0
REGS2_k127_2034469_27 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000001813 197.0
REGS2_k127_2034469_28 PFAM NUDIX domain - - - 0.000000000000000000000000000000000000000000942 162.0
REGS2_k127_2034469_29 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000007647 171.0
REGS2_k127_2034469_3 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 497.0
REGS2_k127_2034469_30 - - - - 0.000000000000000000000000000000000000008752 151.0
REGS2_k127_2034469_31 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000000000000002359 134.0
REGS2_k127_2034469_32 DoxX family K15977 - - 0.00000000000000000000000000001989 130.0
REGS2_k127_2034469_33 Thioredoxin - - - 0.000000000000000000000004508 110.0
REGS2_k127_2034469_34 COG3806 Anti-sigma factor - - - 0.0000000000000000000003238 101.0
REGS2_k127_2034469_35 ATP-dependent Clp protease adaptor protein ClpS - - - 0.000000000001483 71.0
REGS2_k127_2034469_36 Xre family transcriptional regulator - - - 0.000000000003363 71.0
REGS2_k127_2034469_37 peptidyl-tyrosine sulfation - - - 0.0000002001 64.0
REGS2_k127_2034469_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 475.0
REGS2_k127_2034469_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 465.0
REGS2_k127_2034469_6 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 459.0
REGS2_k127_2034469_7 Peptidase dimerisation domain K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 402.0
REGS2_k127_2034469_8 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 367.0
REGS2_k127_2034469_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 345.0
REGS2_k127_2067818_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 457.0
REGS2_k127_2067818_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 449.0
REGS2_k127_2067818_10 COG3980 Spore coat polysaccharide biosynthesis protein - - - 0.000000000000000003222 91.0
REGS2_k127_2067818_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000005185 81.0
REGS2_k127_2067818_2 acid synthase K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 434.0
REGS2_k127_2067818_3 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 419.0
REGS2_k127_2067818_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002768 238.0
REGS2_k127_2067818_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000001904 233.0
REGS2_k127_2067818_7 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000001325 162.0
REGS2_k127_2067818_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000006482 123.0
REGS2_k127_2067818_9 Methyltransferase type 12 - - - 0.00000000000000000005082 100.0
REGS2_k127_2119877_0 Belongs to the IlvD Edd family - - - 1.877e-234 756.0
REGS2_k127_2119877_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 616.0
REGS2_k127_2119877_10 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 319.0
REGS2_k127_2119877_11 ABC-type sugar transport systems, permease components K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
REGS2_k127_2119877_12 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004956 291.0
REGS2_k127_2119877_13 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004005 282.0
REGS2_k127_2119877_14 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 250.0
REGS2_k127_2119877_15 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.000000000000000000000000000000000000000000000000000000000000000009903 231.0
REGS2_k127_2119877_16 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000004257 246.0
REGS2_k127_2119877_17 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000003642 230.0
REGS2_k127_2119877_18 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000005874 207.0
REGS2_k127_2119877_19 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000009862 175.0
REGS2_k127_2119877_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 608.0
REGS2_k127_2119877_20 Aldolase/RraA - - - 0.00000000000000000000000000000000000000005365 164.0
REGS2_k127_2119877_21 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000005311 166.0
REGS2_k127_2119877_22 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000002903 139.0
REGS2_k127_2119877_23 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000004796 135.0
REGS2_k127_2119877_24 Protein conserved in bacteria - - - 0.0004938 53.0
REGS2_k127_2119877_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 606.0
REGS2_k127_2119877_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 410.0
REGS2_k127_2119877_5 carbohydrate transport K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 421.0
REGS2_k127_2119877_6 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
REGS2_k127_2119877_7 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 387.0
REGS2_k127_2119877_8 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 356.0
REGS2_k127_2119877_9 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 319.0
REGS2_k127_21494_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1055.0
REGS2_k127_21494_1 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1034.0
REGS2_k127_21494_10 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 459.0
REGS2_k127_21494_11 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 401.0
REGS2_k127_21494_12 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 392.0
REGS2_k127_21494_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 394.0
REGS2_k127_21494_14 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 382.0
REGS2_k127_21494_15 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 376.0
REGS2_k127_21494_16 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 363.0
REGS2_k127_21494_17 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 326.0
REGS2_k127_21494_18 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 308.0
REGS2_k127_21494_19 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 304.0
REGS2_k127_21494_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.56e-278 879.0
REGS2_k127_21494_20 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
REGS2_k127_21494_21 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000484 297.0
REGS2_k127_21494_22 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000006597 279.0
REGS2_k127_21494_23 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000032 232.0
REGS2_k127_21494_24 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000001953 208.0
REGS2_k127_21494_25 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000589 195.0
REGS2_k127_21494_26 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000001335 196.0
REGS2_k127_21494_27 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000005156 194.0
REGS2_k127_21494_28 EamA-like transporter family - - - 0.0000000000000000000000000000000001908 144.0
REGS2_k127_21494_29 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000368 134.0
REGS2_k127_21494_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.391e-277 877.0
REGS2_k127_21494_30 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000001529 130.0
REGS2_k127_21494_31 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000000000005395 114.0
REGS2_k127_21494_32 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000251 105.0
REGS2_k127_21494_33 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000005815 106.0
REGS2_k127_21494_34 Tetratricopeptide repeat - - - 0.000000000000000002379 94.0
REGS2_k127_21494_35 OstA-like protein K09774 - - 0.00000000000000001815 92.0
REGS2_k127_21494_36 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000003315 72.0
REGS2_k127_21494_37 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.00000007454 61.0
REGS2_k127_21494_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.537e-241 758.0
REGS2_k127_21494_5 adenosylhomocysteinase activity K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 595.0
REGS2_k127_21494_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 567.0
REGS2_k127_21494_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 567.0
REGS2_k127_21494_8 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 508.0
REGS2_k127_21494_9 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 471.0
REGS2_k127_2230407_0 DNA polymerase type-B family K02336 - 2.7.7.7 5.905e-210 678.0
REGS2_k127_2230407_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 370.0
REGS2_k127_2230407_10 Domain of unknown function (DUF309) K09763 - - 0.0000344 56.0
REGS2_k127_2230407_11 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.0007079 51.0
REGS2_k127_2230407_2 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 307.0
REGS2_k127_2230407_3 Enoyl-(Acyl carrier protein) reductase K00059,K19550 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001785 229.0
REGS2_k127_2230407_4 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000009486 185.0
REGS2_k127_2230407_5 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000003956 147.0
REGS2_k127_2230407_6 RNA recognition motif - - - 0.00000000000000000000000001576 112.0
REGS2_k127_2230407_7 RDD family - - - 0.000000000004604 74.0
REGS2_k127_2230407_8 Virulence factor BrkB K07058 - - 0.000000006539 68.0
REGS2_k127_2230407_9 DSBA-like thioredoxin domain - - - 0.00002129 53.0
REGS2_k127_2272077_0 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 9.916e-233 739.0
REGS2_k127_2272077_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 462.0
REGS2_k127_2272077_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000115 259.0
REGS2_k127_2272077_11 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000442 238.0
REGS2_k127_2272077_12 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000005371 227.0
REGS2_k127_2272077_13 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000001013 179.0
REGS2_k127_2272077_14 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000006128 165.0
REGS2_k127_2272077_15 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000002454 119.0
REGS2_k127_2272077_16 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.000000000000000002622 100.0
REGS2_k127_2272077_17 Bacterial extracellular solute-binding protein K02027,K17329 - - 0.0000000003759 73.0
REGS2_k127_2272077_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 450.0
REGS2_k127_2272077_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 459.0
REGS2_k127_2272077_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 404.0
REGS2_k127_2272077_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 354.0
REGS2_k127_2272077_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 316.0
REGS2_k127_2272077_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000797 270.0
REGS2_k127_2272077_8 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001947 269.0
REGS2_k127_2272077_9 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008363 261.0
REGS2_k127_2350637_0 Branched-chain amino acid transport system / permease component K01997 - - 6.345e-206 657.0
REGS2_k127_2350637_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 576.0
REGS2_k127_2350637_10 PFAM Acetamidase Formamidase K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 321.0
REGS2_k127_2350637_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 295.0
REGS2_k127_2350637_12 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 303.0
REGS2_k127_2350637_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
REGS2_k127_2350637_14 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002833 262.0
REGS2_k127_2350637_15 4Fe-4S double cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004976 245.0
REGS2_k127_2350637_16 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000009533 188.0
REGS2_k127_2350637_17 diguanylate cyclase - - - 0.00000000000000000000000000000000000000006034 171.0
REGS2_k127_2350637_18 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000002866 162.0
REGS2_k127_2350637_19 GAF domain - - - 0.00000000000000000000000000000000008806 149.0
REGS2_k127_2350637_2 Domain in cystathionine beta-synthase and other proteins. K14446 - 1.3.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 543.0
REGS2_k127_2350637_20 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000001104 148.0
REGS2_k127_2350637_21 Amidohydrolase family K15358 - 3.5.2.18 0.0000000000000185 85.0
REGS2_k127_2350637_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000002311 73.0
REGS2_k127_2350637_23 PAS fold-4 domain protein - - - 0.000000000004692 80.0
REGS2_k127_2350637_24 DoxX K15977 - - 0.00007225 51.0
REGS2_k127_2350637_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 430.0
REGS2_k127_2350637_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 441.0
REGS2_k127_2350637_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 411.0
REGS2_k127_2350637_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 356.0
REGS2_k127_2350637_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 359.0
REGS2_k127_2350637_8 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 370.0
REGS2_k127_2350637_9 Family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 353.0
REGS2_k127_2378281_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 9.438e-195 625.0
REGS2_k127_2378281_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 466.0
REGS2_k127_2378281_10 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000006397 65.0
REGS2_k127_2378281_11 TIGRFAM phage plasmid primase, P4 family, C-terminal domain K06919 - - 0.000005699 56.0
REGS2_k127_2378281_12 Helix-turn-helix domain - - - 0.0001769 49.0
REGS2_k127_2378281_13 Helix-turn-helix domain - - - 0.0003371 47.0
REGS2_k127_2378281_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 426.0
REGS2_k127_2378281_3 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 407.0
REGS2_k127_2378281_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
REGS2_k127_2378281_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003152 271.0
REGS2_k127_2378281_6 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000001497 164.0
REGS2_k127_2378281_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.0000000000000000000000001746 107.0
REGS2_k127_2378281_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000004105 103.0
REGS2_k127_2378281_9 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000001009 87.0
REGS2_k127_250303_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1439.0
REGS2_k127_250303_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 8.612e-318 996.0
REGS2_k127_250303_10 Protein of unknown function (DUF1624) - - - 0.0000000003811 71.0
REGS2_k127_250303_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001713 67.0
REGS2_k127_250303_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K16877 - 1.3.99.8 1.241e-276 873.0
REGS2_k127_250303_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 362.0
REGS2_k127_250303_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 310.0
REGS2_k127_250303_5 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000596 211.0
REGS2_k127_250303_6 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.0000000000000000000000000000000000000000000000000002248 205.0
REGS2_k127_250303_7 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000008523 140.0
REGS2_k127_250303_8 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000001373 105.0
REGS2_k127_2600690_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 424.0
REGS2_k127_2600690_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002106 272.0
REGS2_k127_2600690_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000008014 241.0
REGS2_k127_2600690_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000005087 233.0
REGS2_k127_2600690_4 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000003322 236.0
REGS2_k127_2600690_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000002228 220.0
REGS2_k127_2605317_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding K00179 - 1.2.7.8 1.592e-256 809.0
REGS2_k127_2605317_1 Carbamoyltransferase C-terminus K00612 - - 2.77e-250 786.0
REGS2_k127_2605317_10 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 511.0
REGS2_k127_2605317_11 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 490.0
REGS2_k127_2605317_12 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 469.0
REGS2_k127_2605317_13 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 433.0
REGS2_k127_2605317_14 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 423.0
REGS2_k127_2605317_15 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 345.0
REGS2_k127_2605317_16 Enoyl-CoA hydratase/isomerase K20765 - 3.7.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 328.0
REGS2_k127_2605317_17 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 328.0
REGS2_k127_2605317_18 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 319.0
REGS2_k127_2605317_19 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 318.0
REGS2_k127_2605317_2 Thiamine pyrophosphate enzyme, central domain - - - 2.244e-241 761.0
REGS2_k127_2605317_20 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 302.0
REGS2_k127_2605317_21 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 316.0
REGS2_k127_2605317_22 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002464 276.0
REGS2_k127_2605317_23 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005312 270.0
REGS2_k127_2605317_24 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004046 262.0
REGS2_k127_2605317_25 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000006787 258.0
REGS2_k127_2605317_26 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003725 252.0
REGS2_k127_2605317_27 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000002852 259.0
REGS2_k127_2605317_28 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000036 250.0
REGS2_k127_2605317_29 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000003088 235.0
REGS2_k127_2605317_3 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.228e-235 738.0
REGS2_k127_2605317_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006352 246.0
REGS2_k127_2605317_31 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006563 236.0
REGS2_k127_2605317_32 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000002506 247.0
REGS2_k127_2605317_33 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000694 231.0
REGS2_k127_2605317_34 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000001082 220.0
REGS2_k127_2605317_35 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000001569 222.0
REGS2_k127_2605317_36 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000005722 220.0
REGS2_k127_2605317_37 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000002334 208.0
REGS2_k127_2605317_38 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000005819 207.0
REGS2_k127_2605317_39 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000154 205.0
REGS2_k127_2605317_4 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 3.86e-215 676.0
REGS2_k127_2605317_40 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000002158 194.0
REGS2_k127_2605317_41 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000004069 200.0
REGS2_k127_2605317_42 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000037 186.0
REGS2_k127_2605317_43 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000003037 189.0
REGS2_k127_2605317_44 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000006721 191.0
REGS2_k127_2605317_45 Adenylate guanylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000008968 174.0
REGS2_k127_2605317_46 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000009877 181.0
REGS2_k127_2605317_47 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000001536 180.0
REGS2_k127_2605317_48 Ligand-binding protein K01999 - - 0.000000000000000000000000000000000000000007696 168.0
REGS2_k127_2605317_49 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000005112 152.0
REGS2_k127_2605317_5 Drug exporters of the RND superfamily K06994 - - 8.788e-212 683.0
REGS2_k127_2605317_50 - - - - 0.000000000000000000000000000000000000004891 156.0
REGS2_k127_2605317_51 Ligand-binding protein K01999 - - 0.00000000000000000000000000000000000001975 158.0
REGS2_k127_2605317_52 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000001609 154.0
REGS2_k127_2605317_53 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000449 143.0
REGS2_k127_2605317_54 - - - - 0.000000000000000000000000000000000006908 154.0
REGS2_k127_2605317_55 - - - - 0.0000000000000000000000000000000002757 142.0
REGS2_k127_2605317_56 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002686 143.0
REGS2_k127_2605317_57 cheY-homologous receiver domain - - - 0.000000000000000000000000000000005811 137.0
REGS2_k127_2605317_58 LTXXQ motif family protein - - - 0.00000000000000000000000000000001198 134.0
REGS2_k127_2605317_59 OmpA-like transmembrane domain K16079 - - 0.00000000000000000000000000000009055 134.0
REGS2_k127_2605317_6 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 588.0
REGS2_k127_2605317_60 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000007028 138.0
REGS2_k127_2605317_61 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000003769 116.0
REGS2_k127_2605317_62 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000007517 114.0
REGS2_k127_2605317_63 rRNA (guanine-N2-)-methyltransferase activity - - - 0.0000000000000000000000003857 115.0
REGS2_k127_2605317_64 Protein of unknown function (DUF3309) - - - 0.0000000000000001078 80.0
REGS2_k127_2605317_65 ABC transporter, permease protein K02004 - - 0.0000000000000001538 80.0
REGS2_k127_2605317_66 SNARE associated Golgi protein K03975 - - 0.00000000000003549 87.0
REGS2_k127_2605317_68 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000009024 79.0
REGS2_k127_2605317_69 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000001578 76.0
REGS2_k127_2605317_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 523.0
REGS2_k127_2605317_70 - - - - 0.00000000006575 68.0
REGS2_k127_2605317_71 - - - - 0.00000000006764 64.0
REGS2_k127_2605317_72 - - - - 0.000000001336 62.0
REGS2_k127_2605317_73 Protein of unknown function (DUF3096) - - - 0.00000001187 57.0
REGS2_k127_2605317_74 Polysulphide reductase, NrfD - - - 0.00000001282 68.0
REGS2_k127_2605317_75 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.0000001066 66.0
REGS2_k127_2605317_76 COGs COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase K19710 - 2.7.7.53 0.000001348 59.0
REGS2_k127_2605317_77 - - - - 0.000003276 55.0
REGS2_k127_2605317_79 protein transport across the cell outer membrane K02453,K03219 - - 0.00002838 55.0
REGS2_k127_2605317_8 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 529.0
REGS2_k127_2605317_9 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 516.0
REGS2_k127_2622774_0 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000002219 266.0
REGS2_k127_2622774_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000001446 217.0
REGS2_k127_2622774_2 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000003214 222.0
REGS2_k127_2622774_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000003441 196.0
REGS2_k127_2622774_4 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000003221 116.0
REGS2_k127_2622774_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000006253 120.0
REGS2_k127_2622774_6 - - - - 0.0000000007098 67.0
REGS2_k127_26584_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 469.0
REGS2_k127_26584_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 355.0
REGS2_k127_26584_2 lactate metabolic process - - - 0.000000000000000000000000000000000000001743 160.0
REGS2_k127_26584_3 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000193 139.0
REGS2_k127_26584_5 CoA-transferase family III K18702 - 2.8.3.19 0.000009077 56.0
REGS2_k127_266969_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.308e-239 761.0
REGS2_k127_266969_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 1.128e-225 724.0
REGS2_k127_266969_10 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000003611 198.0
REGS2_k127_266969_11 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000002395 198.0
REGS2_k127_266969_12 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000005704 153.0
REGS2_k127_266969_13 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000009711 133.0
REGS2_k127_266969_14 Putative regulatory protein - - - 0.00000000000000001139 87.0
REGS2_k127_266969_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.000000000000001222 90.0
REGS2_k127_266969_16 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000002775 84.0
REGS2_k127_266969_17 ABC transporter K06147 - - 0.000000000004437 76.0
REGS2_k127_266969_18 Evidence 5 No homology to any previously reported sequences K03765 - - 0.00000000001896 75.0
REGS2_k127_266969_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.00000000009135 65.0
REGS2_k127_266969_2 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 8.314e-214 676.0
REGS2_k127_266969_20 - - - - 0.00000003498 66.0
REGS2_k127_266969_21 cAMP biosynthetic process - - - 0.0000009423 61.0
REGS2_k127_266969_22 Gas vesicle protein - - - 0.0002876 48.0
REGS2_k127_266969_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 589.0
REGS2_k127_266969_4 Transglycosylase K05365,K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 484.0
REGS2_k127_266969_5 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
REGS2_k127_266969_6 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 376.0
REGS2_k127_266969_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 318.0
REGS2_k127_266969_8 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 297.0
REGS2_k127_266969_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000001676 235.0
REGS2_k127_2762831_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.581e-273 858.0
REGS2_k127_2762831_1 transport system fused permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 582.0
REGS2_k127_2762831_10 Domain of unknown function (DUF1730) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001387 289.0
REGS2_k127_2762831_11 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
REGS2_k127_2762831_12 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000587 218.0
REGS2_k127_2762831_13 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000003613 217.0
REGS2_k127_2762831_14 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000006682 209.0
REGS2_k127_2762831_15 TRAP transporter solute receptor TAXI family protein K07080 - - 0.000000000000000000000000000000000000000000000003191 196.0
REGS2_k127_2762831_16 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000001976 169.0
REGS2_k127_2762831_17 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000002456 162.0
REGS2_k127_2762831_18 MaoC like domain - - - 0.0000000000000000000000000000000000002819 158.0
REGS2_k127_2762831_19 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000003355 126.0
REGS2_k127_2762831_2 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 531.0
REGS2_k127_2762831_20 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000005787 106.0
REGS2_k127_2762831_21 Belongs to the GcvT family K06980 - - 0.0000000000000005129 81.0
REGS2_k127_2762831_22 MaoC like domain - - - 0.000000579 61.0
REGS2_k127_2762831_23 - - - - 0.0001872 49.0
REGS2_k127_2762831_3 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 374.0
REGS2_k127_2762831_4 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 331.0
REGS2_k127_2762831_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 331.0
REGS2_k127_2762831_6 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
REGS2_k127_2762831_7 Belongs to the UbiD family K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 329.0
REGS2_k127_2762831_8 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 309.0
REGS2_k127_2762831_9 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003973 282.0
REGS2_k127_2763543_0 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00392 - 1.7.7.1,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 554.0
REGS2_k127_2763543_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K00380,K02567 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.7.7.2,1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 511.0
REGS2_k127_2763543_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000007089 57.0
REGS2_k127_2805237_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 578.0
REGS2_k127_2805237_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 467.0
REGS2_k127_2805237_2 Belongs to the TtcA family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 334.0
REGS2_k127_2805237_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000002259 220.0
REGS2_k127_2805237_4 Cupin domain K11312 - - 0.000000000000000000000000000000000000006278 147.0
REGS2_k127_2805237_5 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000001214 127.0
REGS2_k127_2805237_7 Cupin superfamily (DUF985) K09705 - - 0.0000000000000007768 86.0
REGS2_k127_2805237_8 ThiS family K03154 - - 0.0000000002618 64.0
REGS2_k127_2805237_9 DinB superfamily - - - 0.00002845 56.0
REGS2_k127_2819753_0 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 402.0
REGS2_k127_2819753_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 306.0
REGS2_k127_2819753_11 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000957 73.0
REGS2_k127_2819753_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 297.0
REGS2_k127_2819753_3 PFAM glycoside hydrolase family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000001277 259.0
REGS2_k127_2819753_4 PFAM Major facilitator superfamily MFS-1 - - - 0.00000000000000000000000000000000000000000000004122 192.0
REGS2_k127_2819753_5 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000001439 162.0
REGS2_k127_2819753_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000004825 128.0
REGS2_k127_2819753_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000002083 122.0
REGS2_k127_2819753_8 Protein of unknown function (DUF3568) - - - 0.000000000000000001218 92.0
REGS2_k127_2819753_9 Response regulator receiver - - - 0.0000000000000001358 87.0
REGS2_k127_30672_0 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 548.0
REGS2_k127_30672_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 554.0
REGS2_k127_30672_10 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000138 252.0
REGS2_k127_30672_11 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000002379 261.0
REGS2_k127_30672_12 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000000000000000000000000000000001772 197.0
REGS2_k127_30672_13 Transposase K07483 - - 0.0000000000000000000000000000001131 126.0
REGS2_k127_30672_14 TOBE domain - - - 0.0000000000000000001282 90.0
REGS2_k127_30672_15 Redoxin - - - 0.000000000000000004181 87.0
REGS2_k127_30672_16 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.00000000000000003765 93.0
REGS2_k127_30672_17 Protein of unknown function (DUF2889) - - - 0.0000000000000006256 91.0
REGS2_k127_30672_18 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000007081 82.0
REGS2_k127_30672_19 Redoxin - - - 0.000000000001598 69.0
REGS2_k127_30672_2 ABC transporter transmembrane region K06147,K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 440.0
REGS2_k127_30672_20 Membrane - - - 0.000000000003325 68.0
REGS2_k127_30672_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 406.0
REGS2_k127_30672_4 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 362.0
REGS2_k127_30672_5 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 346.0
REGS2_k127_30672_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
REGS2_k127_30672_7 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001918 289.0
REGS2_k127_30672_8 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008699 291.0
REGS2_k127_30672_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000005009 268.0
REGS2_k127_3102251_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.003e-273 860.0
REGS2_k127_3102251_1 Aconitase family (aconitate hydratase) - - - 2.885e-200 634.0
REGS2_k127_3102251_10 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000004461 141.0
REGS2_k127_3102251_2 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01848 - 5.4.99.2 1.811e-197 628.0
REGS2_k127_3102251_3 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 469.0
REGS2_k127_3102251_4 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 453.0
REGS2_k127_3102251_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 293.0
REGS2_k127_3102251_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001627 281.0
REGS2_k127_3102251_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002656 249.0
REGS2_k127_3102251_8 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008373 261.0
REGS2_k127_3102251_9 2Fe-2S -binding domain protein K18029 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016725,GO:0019439,GO:0044237,GO:0044248,GO:0055114 1.17.2.1 0.00000000000000000000000000000000000000000000000000000000003957 211.0
REGS2_k127_3143887_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 8.214e-273 863.0
REGS2_k127_3143887_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 506.0
REGS2_k127_3143887_10 - - - - 0.00004131 49.0
REGS2_k127_3143887_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 460.0
REGS2_k127_3143887_3 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 389.0
REGS2_k127_3143887_4 Formate dehydrogenase, beta subunit K00124 - - 0.0000000000000000000000000000000000000000000000000000000000002777 221.0
REGS2_k127_3143887_5 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000001063 198.0
REGS2_k127_3143887_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000001716 136.0
REGS2_k127_3143887_7 formate dehydrogenase K00127 - - 0.00000000000000000000001634 115.0
REGS2_k127_3143887_8 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000008901 108.0
REGS2_k127_3143887_9 Redoxin - - - 0.000000000002178 79.0
REGS2_k127_3201738_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 2.352e-205 654.0
REGS2_k127_3201738_1 Carboxyl transferase domain - - - 1.668e-204 657.0
REGS2_k127_3201738_10 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 330.0
REGS2_k127_3201738_11 Gamma-glutamyltranspeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 339.0
REGS2_k127_3201738_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 297.0
REGS2_k127_3201738_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 292.0
REGS2_k127_3201738_14 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000883 304.0
REGS2_k127_3201738_15 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005445 283.0
REGS2_k127_3201738_16 transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003443 279.0
REGS2_k127_3201738_17 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003134 262.0
REGS2_k127_3201738_18 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000755 246.0
REGS2_k127_3201738_19 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000001557 239.0
REGS2_k127_3201738_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K07469 - 1.2.99.7 3.9e-200 660.0
REGS2_k127_3201738_20 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000002063 214.0
REGS2_k127_3201738_21 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000417 181.0
REGS2_k127_3201738_22 PFAM type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000001341 176.0
REGS2_k127_3201738_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000733 161.0
REGS2_k127_3201738_24 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000004094 168.0
REGS2_k127_3201738_25 PFAM cobalbumin biosynthesis protein K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000495 149.0
REGS2_k127_3201738_26 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000002806 144.0
REGS2_k127_3201738_27 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000651 149.0
REGS2_k127_3201738_28 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.00000000000000000000000000000002249 129.0
REGS2_k127_3201738_29 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000001418 143.0
REGS2_k127_3201738_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 447.0
REGS2_k127_3201738_31 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000006027 116.0
REGS2_k127_3201738_32 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000114 105.0
REGS2_k127_3201738_33 cyclic nucleotide binding K10914 - - 0.0000000000000000001438 102.0
REGS2_k127_3201738_34 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000004356 94.0
REGS2_k127_3201738_35 fimbrial assembly K02461 - - 0.000000000000003817 89.0
REGS2_k127_3201738_36 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000009771 70.0
REGS2_k127_3201738_37 Prokaryotic N-terminal methylation motif K02459 - - 0.0000003365 59.0
REGS2_k127_3201738_38 general secretion pathway protein K02457 - - 0.00002158 55.0
REGS2_k127_3201738_39 Type II secretion system (T2SS), protein M subtype b - - - 0.0009708 51.0
REGS2_k127_3201738_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 422.0
REGS2_k127_3201738_5 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 368.0
REGS2_k127_3201738_6 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 358.0
REGS2_k127_3201738_7 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 360.0
REGS2_k127_3201738_8 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 355.0
REGS2_k127_3201738_9 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 336.0
REGS2_k127_3258759_0 Hydantoinase/oxoprolinase - - - 3.361e-268 844.0
REGS2_k127_3258759_1 Hydantoinase B/oxoprolinase - - - 3.392e-256 808.0
REGS2_k127_3258759_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001677 228.0
REGS2_k127_3258759_11 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000008603 194.0
REGS2_k127_3258759_12 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000004671 175.0
REGS2_k127_3258759_13 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000002824 120.0
REGS2_k127_3258759_14 transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000002215 117.0
REGS2_k127_3258759_16 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0005068 49.0
REGS2_k127_3258759_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 516.0
REGS2_k127_3258759_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 445.0
REGS2_k127_3258759_4 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 395.0
REGS2_k127_3258759_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 403.0
REGS2_k127_3258759_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 413.0
REGS2_k127_3258759_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 364.0
REGS2_k127_3258759_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002023 248.0
REGS2_k127_3258759_9 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003475 260.0
REGS2_k127_3259385_0 Radical SAM - - - 8.427e-225 706.0
REGS2_k127_3259385_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 8.579e-220 699.0
REGS2_k127_3259385_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 396.0
REGS2_k127_3259385_11 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 382.0
REGS2_k127_3259385_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 315.0
REGS2_k127_3259385_13 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
REGS2_k127_3259385_14 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 313.0
REGS2_k127_3259385_15 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009009 288.0
REGS2_k127_3259385_16 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 263.0
REGS2_k127_3259385_17 PFAM thiamine pyrophosphate protein domain protein TPP-binding K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000003216 265.0
REGS2_k127_3259385_18 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000001706 250.0
REGS2_k127_3259385_19 Belongs to the malate synthase family K01638 - 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000002846 242.0
REGS2_k127_3259385_2 elongation factor G K02355 - - 1.194e-216 713.0
REGS2_k127_3259385_20 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000002118 241.0
REGS2_k127_3259385_21 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000003017 208.0
REGS2_k127_3259385_22 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000000003744 202.0
REGS2_k127_3259385_23 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000001337 171.0
REGS2_k127_3259385_24 - - - - 0.000000000000000000005054 97.0
REGS2_k127_3259385_25 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.0000000000001679 83.0
REGS2_k127_3259385_26 Antibiotic biosynthesis monooxygenase - - - 0.000000005472 61.0
REGS2_k127_3259385_27 - - - - 0.00000002368 61.0
REGS2_k127_3259385_28 Phosphorylase superfamily - - - 0.0000005232 61.0
REGS2_k127_3259385_29 Cupin 2, conserved barrel domain protein K19547 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897 5.3.3.19 0.0000428 51.0
REGS2_k127_3259385_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.567e-208 668.0
REGS2_k127_3259385_4 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 570.0
REGS2_k127_3259385_5 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 512.0
REGS2_k127_3259385_6 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 470.0
REGS2_k127_3259385_7 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 466.0
REGS2_k127_3259385_8 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 456.0
REGS2_k127_3259385_9 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 402.0
REGS2_k127_3260103_0 Hydrolase CocE NonD family K06978 - - 7.099e-286 898.0
REGS2_k127_3260103_1 Gaf domain - - - 1.045e-207 672.0
REGS2_k127_3260103_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001515 242.0
REGS2_k127_3260103_11 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000003809 249.0
REGS2_k127_3260103_12 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000005052 234.0
REGS2_k127_3260103_13 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000001431 217.0
REGS2_k127_3260103_14 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001746 206.0
REGS2_k127_3260103_15 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000003879 183.0
REGS2_k127_3260103_16 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000003023 173.0
REGS2_k127_3260103_17 N-acylneuraminate-9-phosphatase activity K01253,K02932,K08726,K10089,K11729 GO:0000166,GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0003995,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006690,GO:0006725,GO:0006793,GO:0006796,GO:0006805,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007031,GO:0007600,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009410,GO:0009636,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015031,GO:0015643,GO:0015833,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016311,GO:0016491,GO:0016627,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0017144,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019369,GO:0019373,GO:0019395,GO:0019439,GO:0019725,GO:0019752,GO:0030003,GO:0030258,GO:0031907,GO:0031974,GO:0032501,GO:0032787,GO:0033036,GO:0033365,GO:0033539,GO:0033559,GO:0034440,GO:0034613,GO:0035150,GO:0035296,GO:0036094,GO:0042221,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042759,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043651,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045777,GO:0046272,GO:0046394,GO:0046395,GO:0046483,GO:0046839,GO:0046872,GO:0046907,GO:0046983,GO:0048037,GO:0048518,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050801,GO:0050877,GO:0050880,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055088,GO:0055092,GO:0055114,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0071466,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072330,GO:0072503,GO:0072507,GO:0072593,GO:0072594,GO:0072662,GO:0072663,GO:0080090,GO:0090066,GO:0090181,GO:0097159,GO:0097176,GO:0097746,GO:0097755,GO:0098771,GO:1900673,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901568,GO:1901575,GO:1901576 3.1.3.76,3.3.2.10,3.3.2.9 0.000000000000000000000000000000000000002044 165.0
REGS2_k127_3260103_18 Major Facilitator Superfamily - - - 0.000000000000000000000005158 115.0
REGS2_k127_3260103_19 PFAM sigma-54 factor interaction domain-containing protein K13599 - - 0.0000000000000000001206 98.0
REGS2_k127_3260103_2 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 621.0
REGS2_k127_3260103_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 545.0
REGS2_k127_3260103_4 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 485.0
REGS2_k127_3260103_5 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 453.0
REGS2_k127_3260103_6 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 441.0
REGS2_k127_3260103_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 380.0
REGS2_k127_3260103_8 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
REGS2_k127_3260103_9 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002201 278.0
REGS2_k127_3388103_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.475e-202 675.0
REGS2_k127_3388103_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 559.0
REGS2_k127_3388103_10 PFAM Na Picotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 402.0
REGS2_k127_3388103_11 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 349.0
REGS2_k127_3388103_12 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 353.0
REGS2_k127_3388103_13 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 357.0
REGS2_k127_3388103_14 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 347.0
REGS2_k127_3388103_15 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 331.0
REGS2_k127_3388103_16 O-Antigen ligase K02847,K13009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 316.0
REGS2_k127_3388103_17 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 303.0
REGS2_k127_3388103_18 Type II secretory pathway component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
REGS2_k127_3388103_19 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001239 281.0
REGS2_k127_3388103_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 519.0
REGS2_k127_3388103_20 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002308 277.0
REGS2_k127_3388103_21 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000002552 276.0
REGS2_k127_3388103_22 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003708 283.0
REGS2_k127_3388103_23 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004323 289.0
REGS2_k127_3388103_24 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005413 272.0
REGS2_k127_3388103_25 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001841 280.0
REGS2_k127_3388103_26 indole-3-glycerol-phosphate synthase activity K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000002218 251.0
REGS2_k127_3388103_27 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000001895 237.0
REGS2_k127_3388103_28 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000006604 220.0
REGS2_k127_3388103_29 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001547 238.0
REGS2_k127_3388103_3 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 553.0
REGS2_k127_3388103_30 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000002483 228.0
REGS2_k127_3388103_31 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000007308 207.0
REGS2_k127_3388103_32 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000008101 207.0
REGS2_k127_3388103_33 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000001022 216.0
REGS2_k127_3388103_34 PFAM Glycosyl K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000003146 200.0
REGS2_k127_3388103_35 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000001462 178.0
REGS2_k127_3388103_36 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000001879 187.0
REGS2_k127_3388103_37 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000766 176.0
REGS2_k127_3388103_38 - - - - 0.0000000000000000000000000000000000000000000005258 187.0
REGS2_k127_3388103_39 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000001033 184.0
REGS2_k127_3388103_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 506.0
REGS2_k127_3388103_40 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000002554 178.0
REGS2_k127_3388103_41 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000008289 172.0
REGS2_k127_3388103_42 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000253 165.0
REGS2_k127_3388103_43 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000006048 154.0
REGS2_k127_3388103_44 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000000000000000000000000000002626 155.0
REGS2_k127_3388103_45 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000004333 139.0
REGS2_k127_3388103_46 methyltransferase - - - 0.0000000000000000000000000000001186 136.0
REGS2_k127_3388103_47 PFAM transport-associated - - - 0.000000000000000000000000000003851 132.0
REGS2_k127_3388103_48 endoribonuclease L-PSP - - - 0.0000000000000000000004913 100.0
REGS2_k127_3388103_49 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000001051 87.0
REGS2_k127_3388103_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 482.0
REGS2_k127_3388103_50 Methyltransferase domain - - - 0.00000000000000001818 98.0
REGS2_k127_3388103_51 Glycosyltransferase like family 2 - - - 0.00000000000000007439 92.0
REGS2_k127_3388103_52 Caenorhabditis protein of unknown function, DUF268 - - - 0.00000000000003661 83.0
REGS2_k127_3388103_53 Methyltransferase small domain - - - 0.00000000000005742 81.0
REGS2_k127_3388103_54 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000001345 77.0
REGS2_k127_3388103_55 - - - - 0.00000000009358 66.0
REGS2_k127_3388103_57 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000005162 59.0
REGS2_k127_3388103_6 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 475.0
REGS2_k127_3388103_7 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 488.0
REGS2_k127_3388103_8 NUBPL iron-transfer P-loop NTPase K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 485.0
REGS2_k127_3388103_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 409.0
REGS2_k127_3555989_0 PFAM iron-containing alcohol dehydrogenase K00001,K11173,K13954 - 1.1.1.1,1.1.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 571.0
REGS2_k127_3555989_1 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 538.0
REGS2_k127_3555989_2 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 400.0
REGS2_k127_3555989_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 362.0
REGS2_k127_3555989_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000005096 237.0
REGS2_k127_3555989_5 MaoC like domain - - - 0.00000000000000000000000000000000000000000002982 182.0
REGS2_k127_3555989_6 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0000000000000000000000000000000000001782 147.0
REGS2_k127_3555989_7 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000001144 124.0
REGS2_k127_3555989_8 B12 binding domain K01849 - 5.4.99.2 0.0000000000008214 71.0
REGS2_k127_3555989_9 Evidence 4 Homologs of previously reported genes of - - - 0.00000009034 57.0
REGS2_k127_3558440_0 DNA methylase K07316 - 2.1.1.72 2.176e-292 923.0
REGS2_k127_3558440_1 Type I site-specific restriction-modification system, R (Restriction) subunit and related K01156 - 3.1.21.5 4.48e-285 910.0
REGS2_k127_3558440_2 amp-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 324.0
REGS2_k127_3558440_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000004674 214.0
REGS2_k127_3558440_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000001811 224.0
REGS2_k127_3558440_5 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000004938 179.0
REGS2_k127_3558440_6 HEPN domain - - - 0.000000000000000007267 89.0
REGS2_k127_3558440_7 Nucleotidyltransferase domain - - - 0.0000000000001038 86.0
REGS2_k127_3570805_0 amino acid - - - 5.004e-211 671.0
REGS2_k127_3570805_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 463.0
REGS2_k127_3570805_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 370.0
REGS2_k127_3570805_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 364.0
REGS2_k127_3570805_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000897 276.0
REGS2_k127_3570805_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001958 259.0
REGS2_k127_3570805_6 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000001205 190.0
REGS2_k127_3570805_7 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000002956 151.0
REGS2_k127_3570805_8 NYN domain - - - 0.000000000004851 77.0
REGS2_k127_3570805_9 php family - - - 0.00000000001224 76.0
REGS2_k127_3616090_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 2.66e-256 822.0
REGS2_k127_3616090_1 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 351.0
REGS2_k127_3616090_2 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 340.0
REGS2_k127_3616090_3 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001181 282.0
REGS2_k127_3616090_4 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001175 279.0
REGS2_k127_3616090_5 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.000000000000000000000000000000000000000000000000000000000000000003455 247.0
REGS2_k127_3616090_6 transmembrane transport - - - 0.0000000000000000000000000000000000000000000002629 176.0
REGS2_k127_3616090_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000242 98.0
REGS2_k127_3616090_8 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000002544 52.0
REGS2_k127_3668020_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 320.0
REGS2_k127_3668020_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 300.0
REGS2_k127_3668020_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02032,K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003704 273.0
REGS2_k127_3668020_3 PFAM RES domain - - - 0.0000000000000000000000000000000000000007135 153.0
REGS2_k127_3668020_4 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000004964 116.0
REGS2_k127_3668020_5 Protein of unknown function (DUF2384) - - - 0.000000000000000000009907 97.0
REGS2_k127_3699584_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 9.527e-209 662.0
REGS2_k127_3699584_1 PFAM AMP-dependent synthetase and ligase - - - 6.649e-201 641.0
REGS2_k127_3699584_10 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000008978 184.0
REGS2_k127_3699584_11 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000001014 196.0
REGS2_k127_3699584_12 Binding-protein-dependent transport system inner membrane component K02029,K10040 - - 0.00000000000000000000000000000000000007318 158.0
REGS2_k127_3699584_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000458 48.0
REGS2_k127_3699584_2 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 572.0
REGS2_k127_3699584_3 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 343.0
REGS2_k127_3699584_4 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 342.0
REGS2_k127_3699584_5 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006126 282.0
REGS2_k127_3699584_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006451 269.0
REGS2_k127_3699584_7 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002457 271.0
REGS2_k127_3699584_8 Belongs to the bacterial solute-binding protein 3 family K09969,K10039 - - 0.00000000000000000000000000000000000000000000000000000000001619 218.0
REGS2_k127_3699584_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000001804 198.0
REGS2_k127_3741875_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.229e-264 827.0
REGS2_k127_3741875_1 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 7.099e-195 618.0
REGS2_k127_3741875_10 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000001776 239.0
REGS2_k127_3741875_11 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000006779 222.0
REGS2_k127_3741875_12 InterPro IPR008538 - - - 0.000000000000000000000000000000000000000000000000000001901 196.0
REGS2_k127_3741875_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000003239 203.0
REGS2_k127_3741875_14 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000001312 175.0
REGS2_k127_3741875_15 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000001019 169.0
REGS2_k127_3741875_16 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000000004507 152.0
REGS2_k127_3741875_17 Serine aminopeptidase, S33 K06889,K07397 - - 0.00000000000000000000000000000008406 141.0
REGS2_k127_3741875_18 Aspartyl protease - - - 0.000000000000001618 82.0
REGS2_k127_3741875_19 Glycosyl transferase, family 2 - - - 0.0000000000002668 72.0
REGS2_k127_3741875_2 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 507.0
REGS2_k127_3741875_20 thiamine biosynthesis protein ThiS K03154 - - 0.0000000002044 66.0
REGS2_k127_3741875_21 Sensory box protein - - - 0.0000000002217 73.0
REGS2_k127_3741875_3 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 492.0
REGS2_k127_3741875_4 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 439.0
REGS2_k127_3741875_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 364.0
REGS2_k127_3741875_6 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 367.0
REGS2_k127_3741875_7 Peptidase family M28 K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 362.0
REGS2_k127_3741875_8 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000119 298.0
REGS2_k127_3741875_9 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000009235 250.0
REGS2_k127_3750929_0 Adenylate and Guanylate cyclase catalytic domain - - - 2.964e-309 984.0
REGS2_k127_3750929_1 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 6.601e-209 675.0
REGS2_k127_3750929_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 583.0
REGS2_k127_3769885_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 605.0
REGS2_k127_3769885_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 480.0
REGS2_k127_3769885_10 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002506 294.0
REGS2_k127_3769885_11 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001882 266.0
REGS2_k127_3769885_12 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004236 252.0
REGS2_k127_3769885_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000008839 212.0
REGS2_k127_3769885_14 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000008349 178.0
REGS2_k127_3769885_15 - - - - 0.000000000000003099 89.0
REGS2_k127_3769885_16 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000002282 79.0
REGS2_k127_3769885_18 - - - - 0.00001378 50.0
REGS2_k127_3769885_2 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 415.0
REGS2_k127_3769885_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 402.0
REGS2_k127_3769885_4 PFAM AMP-dependent synthetase and ligase K01895,K08295 - 6.2.1.1,6.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 383.0
REGS2_k127_3769885_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 361.0
REGS2_k127_3769885_6 FAD binding domain K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 334.0
REGS2_k127_3769885_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 310.0
REGS2_k127_3769885_8 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 319.0
REGS2_k127_3769885_9 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 308.0
REGS2_k127_3770744_0 Aconitase C-terminal domain K01681 - 4.2.1.3 3.776e-231 732.0
REGS2_k127_3770744_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 1.916e-213 677.0
REGS2_k127_3770744_10 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 397.0
REGS2_k127_3770744_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 379.0
REGS2_k127_3770744_12 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 404.0
REGS2_k127_3770744_13 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 376.0
REGS2_k127_3770744_14 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 338.0
REGS2_k127_3770744_15 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 337.0
REGS2_k127_3770744_16 PrpF protein K09788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 353.0
REGS2_k127_3770744_17 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 334.0
REGS2_k127_3770744_18 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 304.0
REGS2_k127_3770744_19 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 306.0
REGS2_k127_3770744_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 568.0
REGS2_k127_3770744_20 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 300.0
REGS2_k127_3770744_21 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004058 263.0
REGS2_k127_3770744_22 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005021 259.0
REGS2_k127_3770744_23 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004447 273.0
REGS2_k127_3770744_24 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000001299 259.0
REGS2_k127_3770744_25 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000001236 247.0
REGS2_k127_3770744_26 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000009307 237.0
REGS2_k127_3770744_27 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000005398 211.0
REGS2_k127_3770744_28 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000091 193.0
REGS2_k127_3770744_29 Sterol carrier protein - - - 0.000000000000000000000000000000000000000002608 158.0
REGS2_k127_3770744_3 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 556.0
REGS2_k127_3770744_30 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K15866,K20036 - 4.2.1.155,4.2.1.17,5.3.3.18 0.000000000000000000000000000000000001959 154.0
REGS2_k127_3770744_31 - - - - 0.00000000000000000000000000000000000491 152.0
REGS2_k127_3770744_32 MaoC like domain - - - 0.000000000000000000000000000000000007056 152.0
REGS2_k127_3770744_33 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000002716 144.0
REGS2_k127_3770744_34 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.000000000000000000000000004452 113.0
REGS2_k127_3770744_35 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000003101 110.0
REGS2_k127_3770744_36 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000003097 109.0
REGS2_k127_3770744_37 Diguanylate cyclase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609 - 0.0000000000000000000009813 111.0
REGS2_k127_3770744_38 O-Methyltransferase K00588 - 2.1.1.104 0.000000000000000000001057 107.0
REGS2_k127_3770744_39 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000002907 92.0
REGS2_k127_3770744_4 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 559.0
REGS2_k127_3770744_40 Thioredoxin-like - - - 0.000000000003674 70.0
REGS2_k127_3770744_42 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000926 63.0
REGS2_k127_3770744_43 Thioredoxin-like - - - 0.0000008513 59.0
REGS2_k127_3770744_44 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00001308 52.0
REGS2_k127_3770744_45 Redoxin K03564 - 1.11.1.15 0.00001567 53.0
REGS2_k127_3770744_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 466.0
REGS2_k127_3770744_6 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 466.0
REGS2_k127_3770744_7 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 459.0
REGS2_k127_3770744_8 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 428.0
REGS2_k127_3770744_9 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 422.0
REGS2_k127_3947694_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1311.0
REGS2_k127_3947694_1 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 608.0
REGS2_k127_3947694_10 cell redox homeostasis K02199 - - 0.00005287 50.0
REGS2_k127_3947694_2 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 351.0
REGS2_k127_3947694_3 COG2513 PEP phosphonomutase and related enzymes K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 321.0
REGS2_k127_3947694_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000009563 210.0
REGS2_k127_3947694_5 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000001678 109.0
REGS2_k127_3947694_6 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000001114 98.0
REGS2_k127_3947694_7 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.00000000001796 74.0
REGS2_k127_3947694_8 Thioredoxin-like - - - 0.00000000002853 67.0
REGS2_k127_3976396_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.551e-270 858.0
REGS2_k127_3976396_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 4.363e-251 782.0
REGS2_k127_3976396_10 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000008645 256.0
REGS2_k127_3976396_11 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000003147 239.0
REGS2_k127_3976396_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000001499 226.0
REGS2_k127_3976396_13 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000003669 215.0
REGS2_k127_3976396_14 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000002221 201.0
REGS2_k127_3976396_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000002449 171.0
REGS2_k127_3976396_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000008756 144.0
REGS2_k127_3976396_17 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000122 115.0
REGS2_k127_3976396_18 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000002241 116.0
REGS2_k127_3976396_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000643 99.0
REGS2_k127_3976396_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 4.138e-245 767.0
REGS2_k127_3976396_20 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000001501 97.0
REGS2_k127_3976396_21 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000005709 66.0
REGS2_k127_3976396_22 Protein of unknown function (DUF507) K09804 - - 0.000000001178 65.0
REGS2_k127_3976396_23 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000004872 62.0
REGS2_k127_3976396_24 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000002358 59.0
REGS2_k127_3976396_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 486.0
REGS2_k127_3976396_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 387.0
REGS2_k127_3976396_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 346.0
REGS2_k127_3976396_6 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 319.0
REGS2_k127_3976396_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 318.0
REGS2_k127_3976396_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001907 284.0
REGS2_k127_3976396_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003861 285.0
REGS2_k127_399483_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 617.0
REGS2_k127_399483_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006935 271.0
REGS2_k127_399483_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000003598 231.0
REGS2_k127_399483_3 4Fe-4S dicluster domain K07307 - - 0.000000000000000000000000000000000000000000001405 174.0
REGS2_k127_399483_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000001065 139.0
REGS2_k127_399483_5 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.00000000000000000000000000002551 129.0
REGS2_k127_399483_6 Nitrate reductase delta subunit - - - 0.0000000000000000000454 103.0
REGS2_k127_399483_8 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000005382 69.0
REGS2_k127_3995288_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 601.0
REGS2_k127_3995288_1 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 404.0
REGS2_k127_3995288_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 382.0
REGS2_k127_3995288_3 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 340.0
REGS2_k127_3995288_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 324.0
REGS2_k127_3995288_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
REGS2_k127_3995288_6 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001631 293.0
REGS2_k127_4041465_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007136 281.0
REGS2_k127_4041465_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005967 271.0
REGS2_k127_4041465_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000005547 207.0
REGS2_k127_4041465_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001592 183.0
REGS2_k127_4041465_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000001916 150.0
REGS2_k127_4041465_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000003369 72.0
REGS2_k127_405170_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 492.0
REGS2_k127_405170_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 479.0
REGS2_k127_405170_10 Sugar (and other) transporter - - - 0.0000000000000000000000000000001322 144.0
REGS2_k127_405170_11 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000009639 131.0
REGS2_k127_405170_12 - - - - 0.00000000000000000000000000007449 133.0
REGS2_k127_405170_13 - - - - 0.000000000005829 68.0
REGS2_k127_405170_14 - - - - 0.00000005533 66.0
REGS2_k127_405170_15 - - - - 0.00003128 57.0
REGS2_k127_405170_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 446.0
REGS2_k127_405170_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 393.0
REGS2_k127_405170_4 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 379.0
REGS2_k127_405170_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 331.0
REGS2_k127_405170_6 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001385 284.0
REGS2_k127_405170_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001001 269.0
REGS2_k127_405170_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000002313 159.0
REGS2_k127_405170_9 PFAM MaoC like domain - - - 0.000000000000000000000000000000000001153 150.0
REGS2_k127_4111975_0 alpha/beta hydrolase fold K01563,K22318 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 441.0
REGS2_k127_4111975_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 331.0
REGS2_k127_4111975_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 301.0
REGS2_k127_4111975_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001097 286.0
REGS2_k127_4111975_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004318 286.0
REGS2_k127_4111975_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000007719 224.0
REGS2_k127_4111975_6 Cupin domain - - - 0.00000000000000000000000000000000000000000001997 181.0
REGS2_k127_4111975_7 pathogenesis K12287 - - 0.00000000000000000000000000000000000000000003272 183.0
REGS2_k127_4111975_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000005242 156.0
REGS2_k127_4111975_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010272,GO:0010273,GO:0016530,GO:0016531,GO:0019725,GO:0030003,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042592,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046688,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0061687,GO:0065007,GO:0065008,GO:0097501,GO:0098754,GO:0098771,GO:0140104,GO:1990169 - 0.000718 48.0
REGS2_k127_4133437_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 3.783e-291 908.0
REGS2_k127_4133437_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.784e-217 682.0
REGS2_k127_4133437_10 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 368.0
REGS2_k127_4133437_11 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 388.0
REGS2_k127_4133437_12 TIGRFAM urea ABC transporter, ATP-binding protein UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 318.0
REGS2_k127_4133437_13 response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 310.0
REGS2_k127_4133437_14 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 285.0
REGS2_k127_4133437_15 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000001802 272.0
REGS2_k127_4133437_16 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000226 272.0
REGS2_k127_4133437_17 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000001357 244.0
REGS2_k127_4133437_18 ATPases associated with a variety of cellular activities K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000001639 240.0
REGS2_k127_4133437_19 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000235 244.0
REGS2_k127_4133437_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.487e-211 674.0
REGS2_k127_4133437_20 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000001503 206.0
REGS2_k127_4133437_21 InterPro IPR008538 - - - 0.0000000000000000000000000000000000000000000000000004562 190.0
REGS2_k127_4133437_22 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001361 201.0
REGS2_k127_4133437_23 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000008973 178.0
REGS2_k127_4133437_24 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000269 179.0
REGS2_k127_4133437_25 PFAM Urease beta subunit K01429,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000006443 167.0
REGS2_k127_4133437_26 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000002614 173.0
REGS2_k127_4133437_27 Belongs to the urease beta subunit family K01427,K01428,K01429,K01430,K14048 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016787,GO:0016810,GO:0016811,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575 3.5.1.5 0.00000000000000000000000000000000000000000002639 162.0
REGS2_k127_4133437_28 HDOD domain - - - 0.000000000000000000000000000000000009926 152.0
REGS2_k127_4133437_29 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.00000000000000000000000000000000004527 154.0
REGS2_k127_4133437_3 Periplasmic binding protein domain K01999 - - 8.301e-196 620.0
REGS2_k127_4133437_30 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000204 139.0
REGS2_k127_4133437_31 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000318 141.0
REGS2_k127_4133437_32 ANTAR K22010 - - 0.000000000000000000000000000001431 132.0
REGS2_k127_4133437_33 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000001098 130.0
REGS2_k127_4133437_34 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000002218 128.0
REGS2_k127_4133437_35 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000000002219 130.0
REGS2_k127_4133437_36 regulation of translation K03530 - - 0.000000000000000000000000003883 113.0
REGS2_k127_4133437_37 Sulfurtransferase TusA - - - 0.00000000000000001622 87.0
REGS2_k127_4133437_38 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000006848 82.0
REGS2_k127_4133437_39 enzyme active site formation K03187 - - 0.000000000000005664 80.0
REGS2_k127_4133437_4 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 616.0
REGS2_k127_4133437_5 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 539.0
REGS2_k127_4133437_6 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 432.0
REGS2_k127_4133437_7 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 398.0
REGS2_k127_4133437_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
REGS2_k127_4133437_9 branched-chain amino acid transport system, permease component K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 370.0
REGS2_k127_413411_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1148.0
REGS2_k127_413411_1 PFAM amidohydrolase K01464,K01465 - 3.5.2.2,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 583.0
REGS2_k127_413411_10 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 389.0
REGS2_k127_413411_11 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 337.0
REGS2_k127_413411_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 295.0
REGS2_k127_413411_13 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003124 276.0
REGS2_k127_413411_14 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000495 278.0
REGS2_k127_413411_15 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000006632 277.0
REGS2_k127_413411_16 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001092 266.0
REGS2_k127_413411_17 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006727 267.0
REGS2_k127_413411_18 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009511 252.0
REGS2_k127_413411_19 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001588 256.0
REGS2_k127_413411_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 576.0
REGS2_k127_413411_20 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004014 243.0
REGS2_k127_413411_21 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000983 228.0
REGS2_k127_413411_22 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000001189 229.0
REGS2_k127_413411_23 Gaf domain - - - 0.00000000000000000000000000000000000000000000000000000001347 215.0
REGS2_k127_413411_24 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000006258 201.0
REGS2_k127_413411_25 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000004536 187.0
REGS2_k127_413411_26 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000004583 186.0
REGS2_k127_413411_27 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000007988 139.0
REGS2_k127_413411_28 KR domain - - - 0.00000000000000000000000000000000002078 155.0
REGS2_k127_413411_29 Trypsin-like serine protease - - - 0.000000000000000000000000003104 126.0
REGS2_k127_413411_3 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 503.0
REGS2_k127_413411_30 Domain of unknown function (DUF4387) - - - 0.0000000000000000000000000108 126.0
REGS2_k127_413411_31 Helix-turn-helix domain - - - 0.00000000006526 71.0
REGS2_k127_413411_32 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0005997 43.0
REGS2_k127_413411_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 494.0
REGS2_k127_413411_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 446.0
REGS2_k127_413411_6 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 435.0
REGS2_k127_413411_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 419.0
REGS2_k127_413411_8 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 431.0
REGS2_k127_413411_9 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 414.0
REGS2_k127_4174203_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 476.0
REGS2_k127_4174203_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 441.0
REGS2_k127_4174203_10 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.0000000000000000000000000000000000000002096 163.0
REGS2_k127_4174203_11 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000002098 157.0
REGS2_k127_4174203_12 membrane K08976 - - 0.0000000000000000000000000000000000121 146.0
REGS2_k127_4174203_13 SNARE associated Golgi protein - - - 0.000000000000000000000000000001107 130.0
REGS2_k127_4174203_14 RNA recognition motif - - - 0.0000000000000000000001216 104.0
REGS2_k127_4174203_15 Regulatory protein ArsR - - - 0.000000000000000000003625 99.0
REGS2_k127_4174203_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001507 74.0
REGS2_k127_4174203_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 439.0
REGS2_k127_4174203_3 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 430.0
REGS2_k127_4174203_4 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 373.0
REGS2_k127_4174203_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 348.0
REGS2_k127_4174203_6 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003258 265.0
REGS2_k127_4174203_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002164 262.0
REGS2_k127_4174203_8 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001099 248.0
REGS2_k127_4174203_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000004058 216.0
REGS2_k127_4322742_0 Adenylate and Guanylate cyclase catalytic domain - - - 1.554e-278 897.0
REGS2_k127_4322742_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 313.0
REGS2_k127_4322742_2 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005363 287.0
REGS2_k127_4322742_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000001033 244.0
REGS2_k127_4322742_4 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000001005 218.0
REGS2_k127_4322742_5 Belongs to the CDS family - - - 0.0000000000000000000000000000000000000000000000000000005462 198.0
REGS2_k127_4322742_6 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000002192 184.0
REGS2_k127_4322742_7 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000001915 171.0
REGS2_k127_4322742_8 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000003731 124.0
REGS2_k127_4329411_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 458.0
REGS2_k127_4329411_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 321.0
REGS2_k127_4329411_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004017 292.0
REGS2_k127_4329411_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000002673 130.0
REGS2_k127_4329411_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000002914 90.0
REGS2_k127_4361300_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 590.0
REGS2_k127_4361300_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 366.0
REGS2_k127_4361300_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 340.0
REGS2_k127_4361300_3 Haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003184 248.0
REGS2_k127_4361300_4 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000004777 222.0
REGS2_k127_4361300_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000001694 177.0
REGS2_k127_4361300_6 Aldo/keto reductase family - - - 0.000000000000000000000003548 104.0
REGS2_k127_4361300_8 Pfam:N_methyl_3 K02456,K02650 - - 0.0003354 48.0
REGS2_k127_4389687_0 AMP-binding enzyme - - - 5.445e-244 770.0
REGS2_k127_4389687_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.731e-219 693.0
REGS2_k127_4389687_10 ABC-type dipeptide transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 416.0
REGS2_k127_4389687_11 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 393.0
REGS2_k127_4389687_12 branched-chain amino acid K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 362.0
REGS2_k127_4389687_13 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 358.0
REGS2_k127_4389687_14 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 334.0
REGS2_k127_4389687_15 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 321.0
REGS2_k127_4389687_16 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 332.0
REGS2_k127_4389687_17 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 310.0
REGS2_k127_4389687_18 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 299.0
REGS2_k127_4389687_19 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 300.0
REGS2_k127_4389687_2 Belongs to the amidase family K01426 - 3.5.1.4 3.695e-207 655.0
REGS2_k127_4389687_20 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009509 306.0
REGS2_k127_4389687_21 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000512 268.0
REGS2_k127_4389687_22 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001502 272.0
REGS2_k127_4389687_23 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006948 265.0
REGS2_k127_4389687_24 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005987 266.0
REGS2_k127_4389687_25 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006655 237.0
REGS2_k127_4389687_26 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000001016 224.0
REGS2_k127_4389687_27 flavin adenine dinucleotide binding K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000102 194.0
REGS2_k127_4389687_28 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000001124 164.0
REGS2_k127_4389687_29 Family 5 K02035 - - 0.0000000000000000000000000000000000006035 162.0
REGS2_k127_4389687_3 ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 593.0
REGS2_k127_4389687_30 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000006281 142.0
REGS2_k127_4389687_31 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000116 145.0
REGS2_k127_4389687_32 transmembrane transporter activity K05820 - - 0.0000000000000000003536 100.0
REGS2_k127_4389687_33 Universal stress protein - - - 0.000000000000000001341 94.0
REGS2_k127_4389687_34 Carboxymuconolactone decarboxylase family - - - 0.000001954 61.0
REGS2_k127_4389687_4 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 488.0
REGS2_k127_4389687_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 460.0
REGS2_k127_4389687_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 443.0
REGS2_k127_4389687_7 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 440.0
REGS2_k127_4389687_8 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 432.0
REGS2_k127_4389687_9 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 424.0
REGS2_k127_4390577_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1340.0
REGS2_k127_4390577_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0 1164.0
REGS2_k127_4390577_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 391.0
REGS2_k127_4390577_11 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 381.0
REGS2_k127_4390577_12 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 389.0
REGS2_k127_4390577_13 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 348.0
REGS2_k127_4390577_14 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 331.0
REGS2_k127_4390577_15 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 316.0
REGS2_k127_4390577_16 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 308.0
REGS2_k127_4390577_17 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 317.0
REGS2_k127_4390577_18 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001632 277.0
REGS2_k127_4390577_19 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002506 262.0
REGS2_k127_4390577_2 DEAD DEAH box helicase K03724 - - 6.087e-280 914.0
REGS2_k127_4390577_20 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005748 269.0
REGS2_k127_4390577_21 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001545 246.0
REGS2_k127_4390577_22 ribosylpyrimidine nucleosidase activity K01239,K01250 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000002565 225.0
REGS2_k127_4390577_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000001262 220.0
REGS2_k127_4390577_24 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000001661 230.0
REGS2_k127_4390577_25 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000006241 210.0
REGS2_k127_4390577_26 COG0111 Phosphoglycerate dehydrogenase and related K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000002773 221.0
REGS2_k127_4390577_27 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000001073 200.0
REGS2_k127_4390577_28 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000000000219 194.0
REGS2_k127_4390577_29 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000194 186.0
REGS2_k127_4390577_3 Periplasmic binding protein domain K01999 - - 1.165e-221 699.0
REGS2_k127_4390577_30 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000002515 174.0
REGS2_k127_4390577_31 FR47-like protein - - - 0.00000000000000000000000000000000000000000005538 170.0
REGS2_k127_4390577_32 oxidation-reduction process - - - 0.000000000000000000000000000006889 129.0
REGS2_k127_4390577_33 Protein of unknown function, DUF488 - - - 0.00000000000000000003496 104.0
REGS2_k127_4390577_34 Lrp/AsnC ligand binding domain - - - 0.00000003533 63.0
REGS2_k127_4390577_35 - - - - 0.0000001043 64.0
REGS2_k127_4390577_36 Contains selenocysteine K07401 - - 0.0000008514 52.0
REGS2_k127_4390577_37 transcriptional regulator K03712 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0044212,GO:0045892,GO:0045934,GO:0046677,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071236,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000001654 57.0
REGS2_k127_4390577_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 554.0
REGS2_k127_4390577_5 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 544.0
REGS2_k127_4390577_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 524.0
REGS2_k127_4390577_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 513.0
REGS2_k127_4390577_8 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 482.0
REGS2_k127_4390577_9 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 428.0
REGS2_k127_4466184_0 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 507.0
REGS2_k127_4466184_1 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 529.0
REGS2_k127_4466184_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 311.0
REGS2_k127_4466184_11 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 306.0
REGS2_k127_4466184_12 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 304.0
REGS2_k127_4466184_13 COG3639 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001625 276.0
REGS2_k127_4466184_14 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007021 280.0
REGS2_k127_4466184_15 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006535 269.0
REGS2_k127_4466184_16 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000007473 242.0
REGS2_k127_4466184_17 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000003017 187.0
REGS2_k127_4466184_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000002361 178.0
REGS2_k127_4466184_19 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000009919 187.0
REGS2_k127_4466184_2 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 491.0
REGS2_k127_4466184_20 NIPSNAP - - - 0.000000000000000000000000001519 126.0
REGS2_k127_4466184_21 acetoacetate metabolism regulatory protein AtoC K07714 - - - 0.0000000000000000006646 98.0
REGS2_k127_4466184_22 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000002399 87.0
REGS2_k127_4466184_23 DNA-sulfur modification-associated - - - 0.00000000000000004115 93.0
REGS2_k127_4466184_24 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000007672 92.0
REGS2_k127_4466184_25 DinB superfamily - - - 0.0000000000000003013 85.0
REGS2_k127_4466184_26 AMP-binding enzyme - - - 0.00005114 50.0
REGS2_k127_4466184_3 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 462.0
REGS2_k127_4466184_4 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 439.0
REGS2_k127_4466184_5 extracellular solute-binding protein, family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 407.0
REGS2_k127_4466184_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 415.0
REGS2_k127_4466184_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 377.0
REGS2_k127_4466184_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 338.0
REGS2_k127_4466184_9 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 321.0
REGS2_k127_4468811_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.379e-282 888.0
REGS2_k127_4468811_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 456.0
REGS2_k127_4468811_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000001625 62.0
REGS2_k127_4468811_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 414.0
REGS2_k127_4468811_3 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 295.0
REGS2_k127_4468811_4 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 290.0
REGS2_k127_4468811_5 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000001566 126.0
REGS2_k127_4468811_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000001207 100.0
REGS2_k127_4468811_7 Belongs to the 'phage' integrase family - - - 0.00000000000000000000001353 100.0
REGS2_k127_4488433_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 530.0
REGS2_k127_4488433_1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000915 261.0
REGS2_k127_4488433_2 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001648 267.0
REGS2_k127_4488433_3 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
REGS2_k127_4488433_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000006505 166.0
REGS2_k127_4488433_5 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000001146 157.0
REGS2_k127_4488433_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000004696 86.0
REGS2_k127_4488433_7 phosphoesterase, PA-phosphatase K19302 - 3.6.1.27 0.00000001106 64.0
REGS2_k127_45049_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000006379 245.0
REGS2_k127_45049_1 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007525 230.0
REGS2_k127_45049_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000002077 243.0
REGS2_k127_45049_3 Peptidase family M16 - - - 0.0000000000000000000000000000000000000000000000000000000000002539 240.0
REGS2_k127_45049_4 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.0000000000000000000000000000000000000000000000005202 195.0
REGS2_k127_45049_5 Gluconolactonase K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000002144 177.0
REGS2_k127_45049_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000001443 96.0
REGS2_k127_45049_7 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000185 82.0
REGS2_k127_4516328_0 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 4.071e-315 982.0
REGS2_k127_4516328_1 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.529e-273 863.0
REGS2_k127_4516328_10 Nitrile hydratase K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 325.0
REGS2_k127_4516328_11 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 319.0
REGS2_k127_4516328_12 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 299.0
REGS2_k127_4516328_13 Serine hydrolase (FSH1) K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005776 282.0
REGS2_k127_4516328_14 Phosphatidylinositol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
REGS2_k127_4516328_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005648 272.0
REGS2_k127_4516328_16 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000513 251.0
REGS2_k127_4516328_17 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
REGS2_k127_4516328_18 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008754 258.0
REGS2_k127_4516328_19 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000001532 237.0
REGS2_k127_4516328_2 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 5.497e-225 718.0
REGS2_k127_4516328_20 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000004061 209.0
REGS2_k127_4516328_21 leucine import across plasma membrane K01997 - - 0.00000000000000000000000000000000000000000000000003344 198.0
REGS2_k127_4516328_22 - - - - 0.000000000000000000000000000000000000000000000191 173.0
REGS2_k127_4516328_23 branched-chain amino acid transport system, permease component K01998 - - 0.00000000000000000000000000000000000002101 165.0
REGS2_k127_4516328_24 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000007623 149.0
REGS2_k127_4516328_25 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000003972 157.0
REGS2_k127_4516328_26 Protein of unknown function (DUF3090) - - - 0.000000000000000000000000000008069 133.0
REGS2_k127_4516328_27 Putative cyclase - - - 0.0007563 44.0
REGS2_k127_4516328_3 peptidase, M20 - - - 4.406e-203 647.0
REGS2_k127_4516328_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 7.383e-196 628.0
REGS2_k127_4516328_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 529.0
REGS2_k127_4516328_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 424.0
REGS2_k127_4516328_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 410.0
REGS2_k127_4516328_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 351.0
REGS2_k127_4516328_9 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 360.0
REGS2_k127_4530468_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 451.0
REGS2_k127_4530468_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 402.0
REGS2_k127_4530468_2 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000002179 170.0
REGS2_k127_4530468_3 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000001527 139.0
REGS2_k127_4530468_4 Calx-beta domain - - - 0.000000000000000000000000000004572 139.0
REGS2_k127_4530468_5 TIGRFAM clan AA aspartic protease, AF_0612 family - - - 0.0001352 52.0
REGS2_k127_4561923_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 0.0 1013.0
REGS2_k127_4561923_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 599.0
REGS2_k127_4561923_10 PFAM ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 334.0
REGS2_k127_4561923_11 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 334.0
REGS2_k127_4561923_12 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 339.0
REGS2_k127_4561923_13 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 326.0
REGS2_k127_4561923_14 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 331.0
REGS2_k127_4561923_15 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 325.0
REGS2_k127_4561923_16 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
REGS2_k127_4561923_17 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 296.0
REGS2_k127_4561923_18 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001744 278.0
REGS2_k127_4561923_19 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002395 264.0
REGS2_k127_4561923_2 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 484.0
REGS2_k127_4561923_20 'Molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000001326 227.0
REGS2_k127_4561923_21 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000008377 226.0
REGS2_k127_4561923_22 TIGRFAM MoaD family protein K03636 - - 0.00000000000000000000000000000002518 127.0
REGS2_k127_4561923_23 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000002602 134.0
REGS2_k127_4561923_24 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000004196 99.0
REGS2_k127_4561923_25 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001345 89.0
REGS2_k127_4561923_26 methionine transport K02071 - - 0.00000000000000004562 88.0
REGS2_k127_4561923_27 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000003027 75.0
REGS2_k127_4561923_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01766,K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 449.0
REGS2_k127_4561923_4 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 405.0
REGS2_k127_4561923_5 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 400.0
REGS2_k127_4561923_6 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 385.0
REGS2_k127_4561923_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
REGS2_k127_4561923_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 377.0
REGS2_k127_4561923_9 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 347.0
REGS2_k127_4583185_0 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 531.0
REGS2_k127_4583185_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 532.0
REGS2_k127_4583185_10 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000003575 227.0
REGS2_k127_4583185_11 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000333 228.0
REGS2_k127_4583185_12 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.000000000000000000000000000000000000000000000000000004421 196.0
REGS2_k127_4583185_13 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000006723 201.0
REGS2_k127_4583185_14 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000001401 195.0
REGS2_k127_4583185_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000008352 173.0
REGS2_k127_4583185_16 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000008465 123.0
REGS2_k127_4583185_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 501.0
REGS2_k127_4583185_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 367.0
REGS2_k127_4583185_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 303.0
REGS2_k127_4583185_5 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 317.0
REGS2_k127_4583185_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000295 283.0
REGS2_k127_4583185_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 275.0
REGS2_k127_4583185_8 Belongs to the enoyl-CoA hydratase isomerase family K16880 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001544 253.0
REGS2_k127_4583185_9 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000001785 258.0
REGS2_k127_4696951_0 Enoyl-CoA hydratase/isomerase - - - 3.198e-239 761.0
REGS2_k127_4696951_1 benzoyl-CoA oxygenase - - - 4.87e-235 737.0
REGS2_k127_4696951_2 xanthine dehydrogenase activity K04108 - 1.3.7.9 9.164e-232 731.0
REGS2_k127_4696951_3 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 392.0
REGS2_k127_4696951_4 AraC-like ligand binding domain - - - 0.0000000000000005587 87.0
REGS2_k127_4781808_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 512.0
REGS2_k127_4781808_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000523 142.0
REGS2_k127_4781808_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000008787 138.0
REGS2_k127_4781808_3 Helix-turn-helix domain K21498 - - 0.000000002053 58.0
REGS2_k127_4846298_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1095.0
REGS2_k127_4846298_1 von Willebrand factor (vWF) type A domain - - - 6.48e-221 709.0
REGS2_k127_4846298_10 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
REGS2_k127_4846298_11 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005677 283.0
REGS2_k127_4846298_12 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000002107 259.0
REGS2_k127_4846298_13 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000001716 245.0
REGS2_k127_4846298_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000004124 232.0
REGS2_k127_4846298_15 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000005576 188.0
REGS2_k127_4846298_16 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000005779 161.0
REGS2_k127_4846298_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 1.978e-205 646.0
REGS2_k127_4846298_3 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 1.508e-200 649.0
REGS2_k127_4846298_4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 522.0
REGS2_k127_4846298_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 490.0
REGS2_k127_4846298_6 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 465.0
REGS2_k127_4846298_7 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 394.0
REGS2_k127_4846298_8 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 340.0
REGS2_k127_4846298_9 serine-type endopeptidase activity K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 300.0
REGS2_k127_4863702_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1304.0
REGS2_k127_4863702_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1068.0
REGS2_k127_4863702_2 GMP synthase (glutamine-hydrolyzing) activity K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 2.731e-210 664.0
REGS2_k127_4863702_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 494.0
REGS2_k127_4863702_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 384.0
REGS2_k127_4863702_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005081 276.0
REGS2_k127_4863702_6 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005472 293.0
REGS2_k127_4863702_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000001112 166.0
REGS2_k127_4882470_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 407.0
REGS2_k127_4882470_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
REGS2_k127_4882470_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 256.0
REGS2_k127_4882470_3 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000008952 228.0
REGS2_k127_4882470_4 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000003154 208.0
REGS2_k127_4882470_5 NMT1-like family - - - 0.0000000000000000000000000000000006604 136.0
REGS2_k127_4882470_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000001367 123.0
REGS2_k127_4882470_7 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000001196 123.0
REGS2_k127_4882470_8 Peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000001833 105.0
REGS2_k127_4895533_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 542.0
REGS2_k127_4895533_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 447.0
REGS2_k127_4895533_2 Inositol monophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000006753 237.0
REGS2_k127_4895533_3 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000003402 224.0
REGS2_k127_4895533_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000005084 136.0
REGS2_k127_4895533_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000008234 129.0
REGS2_k127_4895533_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000376 123.0
REGS2_k127_4895533_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000002848 95.0
REGS2_k127_5052815_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 2.919e-271 871.0
REGS2_k127_5052815_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.214e-209 661.0
REGS2_k127_5052815_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000001324 245.0
REGS2_k127_5052815_11 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000277 229.0
REGS2_k127_5052815_12 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000002983 231.0
REGS2_k127_5052815_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000007336 234.0
REGS2_k127_5052815_14 PFAM ABC transporter related K02065 - - 0.00000000000000000000000000000000000000000000000000000000000001582 223.0
REGS2_k127_5052815_15 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000122 230.0
REGS2_k127_5052815_16 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000001238 224.0
REGS2_k127_5052815_17 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000003173 208.0
REGS2_k127_5052815_18 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000009647 188.0
REGS2_k127_5052815_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000463 186.0
REGS2_k127_5052815_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 514.0
REGS2_k127_5052815_20 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000507 191.0
REGS2_k127_5052815_21 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000002311 185.0
REGS2_k127_5052815_22 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000423 157.0
REGS2_k127_5052815_23 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000002936 121.0
REGS2_k127_5052815_24 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001664 80.0
REGS2_k127_5052815_26 - - - - 0.0000001745 61.0
REGS2_k127_5052815_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 513.0
REGS2_k127_5052815_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 481.0
REGS2_k127_5052815_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 442.0
REGS2_k127_5052815_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 422.0
REGS2_k127_5052815_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500,K11755 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 366.0
REGS2_k127_5052815_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002759 268.0
REGS2_k127_5052815_9 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
REGS2_k127_506248_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 554.0
REGS2_k127_506248_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 453.0
REGS2_k127_506248_2 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 454.0
REGS2_k127_506248_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 375.0
REGS2_k127_506248_4 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 340.0
REGS2_k127_506248_5 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 299.0
REGS2_k127_506248_6 NIPSNAP - - - 0.000000000000000000071 94.0
REGS2_k127_506248_7 Putative peptidoglycan binding domain - - - 0.00000000000000005716 93.0
REGS2_k127_5069622_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 422.0
REGS2_k127_5069622_1 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 372.0
REGS2_k127_5069622_2 ABC-type multidrug transport system ATPase K01990,K16907 - - 0.00000000000000000000000000000000000000000000000000000000000003202 224.0
REGS2_k127_5069622_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000005429 211.0
REGS2_k127_5069622_4 Putative FMN-binding domain K07734 - - 0.0000000000000002295 92.0
REGS2_k127_5069622_5 Putative ATP-binding cassette - - - 0.0003875 52.0
REGS2_k127_508944_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 475.0
REGS2_k127_508944_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 448.0
REGS2_k127_508944_10 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000008932 132.0
REGS2_k127_508944_2 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 451.0
REGS2_k127_508944_3 Beta-lactamase class A K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 306.0
REGS2_k127_508944_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
REGS2_k127_508944_5 High-affinity branched-chain amino acid transport protein (ABC superfamily K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003823 260.0
REGS2_k127_508944_6 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003925 254.0
REGS2_k127_508944_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000003815 229.0
REGS2_k127_508944_8 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000473 204.0
REGS2_k127_508944_9 - - - - 0.000000000000000000000000000000000000000000003279 166.0
REGS2_k127_5323369_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1155.0
REGS2_k127_5323369_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1114.0
REGS2_k127_5323369_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 445.0
REGS2_k127_5323369_11 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 403.0
REGS2_k127_5323369_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 360.0
REGS2_k127_5323369_13 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002448 294.0
REGS2_k127_5323369_14 phosphorelay sensor kinase activity K02668,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001111 284.0
REGS2_k127_5323369_15 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004482 284.0
REGS2_k127_5323369_16 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000006199 245.0
REGS2_k127_5323369_17 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000004336 239.0
REGS2_k127_5323369_18 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000001734 224.0
REGS2_k127_5323369_19 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000006874 217.0
REGS2_k127_5323369_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.986e-221 702.0
REGS2_k127_5323369_20 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000008161 232.0
REGS2_k127_5323369_21 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000001819 217.0
REGS2_k127_5323369_22 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000006083 219.0
REGS2_k127_5323369_23 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000003849 215.0
REGS2_k127_5323369_24 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000006914 185.0
REGS2_k127_5323369_25 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000000000000000009587 157.0
REGS2_k127_5323369_26 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.000000000000000000000000000000002099 140.0
REGS2_k127_5323369_27 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000003069 128.0
REGS2_k127_5323369_28 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000001375 143.0
REGS2_k127_5323369_29 Tetratricopeptide repeat - - - 0.000000000000000000000000001225 124.0
REGS2_k127_5323369_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 616.0
REGS2_k127_5323369_30 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001638 115.0
REGS2_k127_5323369_31 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000008336 123.0
REGS2_k127_5323369_32 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000001002 109.0
REGS2_k127_5323369_33 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000001259 85.0
REGS2_k127_5323369_34 gag-polyprotein putative aspartyl protease - - - 0.0000000000000004647 87.0
REGS2_k127_5323369_35 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000001201 69.0
REGS2_k127_5323369_36 PFAM thiamineS protein - - - 0.00000000194 61.0
REGS2_k127_5323369_37 - - - - 0.000000009923 59.0
REGS2_k127_5323369_38 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000008582 64.0
REGS2_k127_5323369_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 620.0
REGS2_k127_5323369_41 - - - - 0.00002238 53.0
REGS2_k127_5323369_42 Tetratricopeptide TPR_2 repeat protein - - - 0.0001577 50.0
REGS2_k127_5323369_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 602.0
REGS2_k127_5323369_6 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 582.0
REGS2_k127_5323369_7 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 508.0
REGS2_k127_5323369_8 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 488.0
REGS2_k127_5323369_9 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 455.0
REGS2_k127_5373037_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 3.116e-200 641.0
REGS2_k127_5373037_1 Copper resistance protein D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 371.0
REGS2_k127_5373037_10 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000001338 181.0
REGS2_k127_5373037_11 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000001242 158.0
REGS2_k127_5373037_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001249 119.0
REGS2_k127_5373037_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 340.0
REGS2_k127_5373037_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 299.0
REGS2_k127_5373037_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 297.0
REGS2_k127_5373037_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000007924 271.0
REGS2_k127_5373037_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
REGS2_k127_5373037_7 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000001991 238.0
REGS2_k127_5373037_8 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000005489 214.0
REGS2_k127_5373037_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000006101 207.0
REGS2_k127_5373810_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1296.0
REGS2_k127_5373810_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 353.0
REGS2_k127_5373810_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000003279 236.0
REGS2_k127_5373810_3 SMART extracellular solute-binding protein family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000002239 225.0
REGS2_k127_5402057_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 444.0
REGS2_k127_5402057_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 351.0
REGS2_k127_5402057_10 Transposase - - - 0.000001573 57.0
REGS2_k127_5402057_11 Protein of unknown function with PCYCGC motif - - - 0.00005545 54.0
REGS2_k127_5402057_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0009685 48.0
REGS2_k127_5402057_13 MULE transposase domain - - - 0.0009716 48.0
REGS2_k127_5402057_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 361.0
REGS2_k127_5402057_3 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003204 291.0
REGS2_k127_5402057_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000003879 206.0
REGS2_k127_5402057_5 - - - - 0.00000000000000000000000000000000000000004814 162.0
REGS2_k127_5402057_7 Protein conserved in bacteria K09986 - - 0.0000000000000002294 84.0
REGS2_k127_5402057_8 ISXO2-like transposase domain - - - 0.0000000003452 63.0
REGS2_k127_5402057_9 Protein of unknown function with PCYCGC motif - - - 0.0000004257 52.0
REGS2_k127_5477196_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 6.026e-230 724.0
REGS2_k127_5477196_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 455.0
REGS2_k127_5477196_2 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 409.0
REGS2_k127_5510686_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 604.0
REGS2_k127_5510686_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 300.0
REGS2_k127_5510686_2 Hydantoinase B/oxoprolinase - - - 0.000000000000000000000000000000000000000000000000000000000006371 224.0
REGS2_k127_5510686_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000001608 211.0
REGS2_k127_5510686_4 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000005253 206.0
REGS2_k127_5510686_5 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.000000000000000001107 96.0
REGS2_k127_5524101_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 1.2e-207 667.0
REGS2_k127_5524101_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 5.21e-196 644.0
REGS2_k127_5524101_10 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 359.0
REGS2_k127_5524101_11 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 351.0
REGS2_k127_5524101_12 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 362.0
REGS2_k127_5524101_13 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 314.0
REGS2_k127_5524101_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 307.0
REGS2_k127_5524101_15 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 292.0
REGS2_k127_5524101_16 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002168 276.0
REGS2_k127_5524101_17 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003751 261.0
REGS2_k127_5524101_18 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001169 264.0
REGS2_k127_5524101_19 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005548 257.0
REGS2_k127_5524101_2 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 503.0
REGS2_k127_5524101_20 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000006386 259.0
REGS2_k127_5524101_21 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000008946 242.0
REGS2_k127_5524101_22 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000003525 216.0
REGS2_k127_5524101_23 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000006546 212.0
REGS2_k127_5524101_24 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000006132 198.0
REGS2_k127_5524101_25 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000000002286 179.0
REGS2_k127_5524101_27 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000000000008605 147.0
REGS2_k127_5524101_28 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000005045 143.0
REGS2_k127_5524101_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.0000000000000000000000000000000004865 140.0
REGS2_k127_5524101_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 430.0
REGS2_k127_5524101_30 regulation of translation K05788 - - 0.000000000000000000000000000000001374 132.0
REGS2_k127_5524101_31 Lysin motif K06194 - - 0.0000000000000000000000000000001679 138.0
REGS2_k127_5524101_32 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000008989 131.0
REGS2_k127_5524101_33 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000003748 104.0
REGS2_k127_5524101_34 peroxiredoxin activity K01055,K01607 - 3.1.1.24,4.1.1.44 0.000000000000000000001263 106.0
REGS2_k127_5524101_35 regulatory protein, MerR - - - 0.000000000000000000003885 101.0
REGS2_k127_5524101_37 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000451 92.0
REGS2_k127_5524101_38 Major facilitator Superfamily - - - 0.00002848 47.0
REGS2_k127_5524101_39 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0005224 49.0
REGS2_k127_5524101_4 Ferrous iron transport protein B K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 396.0
REGS2_k127_5524101_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 387.0
REGS2_k127_5524101_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 374.0
REGS2_k127_5524101_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 381.0
REGS2_k127_5524101_8 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 367.0
REGS2_k127_5524101_9 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 364.0
REGS2_k127_5548687_0 Carboxyl transferase domain - - - 3.375e-232 728.0
REGS2_k127_5548687_1 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 563.0
REGS2_k127_5588874_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 573.0
REGS2_k127_5588874_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 566.0
REGS2_k127_5588874_10 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000001197 168.0
REGS2_k127_5588874_11 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000002985 176.0
REGS2_k127_5588874_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000006883 136.0
REGS2_k127_5588874_13 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000000000000000388 121.0
REGS2_k127_5588874_14 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000001999 96.0
REGS2_k127_5588874_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000006617 93.0
REGS2_k127_5588874_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 564.0
REGS2_k127_5588874_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 542.0
REGS2_k127_5588874_4 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 427.0
REGS2_k127_5588874_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 325.0
REGS2_k127_5588874_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 342.0
REGS2_k127_5588874_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 336.0
REGS2_k127_5588874_8 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 310.0
REGS2_k127_5588874_9 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
REGS2_k127_5596511_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 471.0
REGS2_k127_5596511_1 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 414.0
REGS2_k127_5596511_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000157 145.0
REGS2_k127_5596511_11 Major Facilitator - - - 0.0000000000000000000000000000000000001943 155.0
REGS2_k127_5596511_12 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000001164 156.0
REGS2_k127_5596511_13 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000005882 150.0
REGS2_k127_5596511_14 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.000000000000000000000000001772 119.0
REGS2_k127_5596511_15 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000008114 111.0
REGS2_k127_5596511_16 Outer membrane lipoprotein - - - 0.0000000000000000007038 98.0
REGS2_k127_5596511_17 Domain of unknown function (DUF4340) - - - 0.000000000007456 78.0
REGS2_k127_5596511_18 PFAM thioesterase superfamily - - - 0.000000555 61.0
REGS2_k127_5596511_19 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000007858 57.0
REGS2_k127_5596511_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
REGS2_k127_5596511_20 Putative zinc-finger - - - 0.00001127 55.0
REGS2_k127_5596511_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 318.0
REGS2_k127_5596511_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001491 293.0
REGS2_k127_5596511_5 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000008693 256.0
REGS2_k127_5596511_6 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000003038 220.0
REGS2_k127_5596511_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000001837 191.0
REGS2_k127_5596511_8 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000001342 170.0
REGS2_k127_5596511_9 PFAM Short-chain dehydrogenase reductase SDR K00059,K03793 - 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000001588 168.0
REGS2_k127_5617986_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0 2083.0
REGS2_k127_5617986_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.0 1131.0
REGS2_k127_5617986_10 dehydrogenase - - - 1.845e-200 645.0
REGS2_k127_5617986_100 Methyltransferase domain - - - 0.00000000000000000000000000000000005267 147.0
REGS2_k127_5617986_101 Putative regulatory protein - - - 0.000000000000000000000000000000007266 132.0
REGS2_k127_5617986_102 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000003885 131.0
REGS2_k127_5617986_103 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000046 129.0
REGS2_k127_5617986_104 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000004787 118.0
REGS2_k127_5617986_105 RNA recognition motif - - - 0.00000000000000000000000003966 111.0
REGS2_k127_5617986_106 subunit of a heme lyase K02198,K02200 - - 0.0000000000000000000000001237 119.0
REGS2_k127_5617986_107 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.00000000000000000000002322 108.0
REGS2_k127_5617986_108 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000008059 112.0
REGS2_k127_5617986_109 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000001998 104.0
REGS2_k127_5617986_11 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 612.0
REGS2_k127_5617986_110 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000003301 98.0
REGS2_k127_5617986_111 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000005159 96.0
REGS2_k127_5617986_112 COG1032 Fe-S oxidoreductase - - - 0.000000000000000000007544 97.0
REGS2_k127_5617986_113 hydroperoxide reductase activity - - - 0.00000000000000000009783 91.0
REGS2_k127_5617986_114 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000008306 95.0
REGS2_k127_5617986_115 glycosyl transferase family 2 K20444 - - 0.000000000000000002444 97.0
REGS2_k127_5617986_116 Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble K03413 - - 0.000000000000005108 79.0
REGS2_k127_5617986_117 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.00000000000000513 81.0
REGS2_k127_5617986_118 MFS_1 like family - - - 0.000000000000006243 87.0
REGS2_k127_5617986_119 Acetyltransferase (GNAT) domain - - - 0.00000000000001914 85.0
REGS2_k127_5617986_12 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 602.0
REGS2_k127_5617986_120 transferase activity, transferring glycosyl groups - - - 0.0000000001424 72.0
REGS2_k127_5617986_121 bacterial-type flagellum-dependent cell motility K01278,K02388,K02396,K03561,K12287 - 3.4.14.5 0.000000001564 75.0
REGS2_k127_5617986_122 DNA topoisomerase II activity K03167 - 5.99.1.3 0.000000002044 70.0
REGS2_k127_5617986_123 PFAM Integrase core domain - - - 0.00000001257 60.0
REGS2_k127_5617986_124 PFAM Cytochrome C - - - 0.00000001758 65.0
REGS2_k127_5617986_125 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.00000003638 66.0
REGS2_k127_5617986_126 Protein of unknown function (DUF3467) - - - 0.000001205 61.0
REGS2_k127_5617986_127 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000004954 59.0
REGS2_k127_5617986_128 - - - - 0.00001734 49.0
REGS2_k127_5617986_129 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000292 51.0
REGS2_k127_5617986_13 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 597.0
REGS2_k127_5617986_130 COG1032 Fe-S oxidoreductase - - - 0.00003188 47.0
REGS2_k127_5617986_132 Lactonase, 7-bladed beta-propeller - - - 0.00025 45.0
REGS2_k127_5617986_133 two component, sigma54 specific, transcriptional regulator, Fis family K07714,K07715 - - 0.0003668 48.0
REGS2_k127_5617986_134 COG3385 FOG Transposase and inactivated derivatives - - - 0.0003762 53.0
REGS2_k127_5617986_135 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000776 48.0
REGS2_k127_5617986_14 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 568.0
REGS2_k127_5617986_15 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 563.0
REGS2_k127_5617986_16 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 601.0
REGS2_k127_5617986_17 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 556.0
REGS2_k127_5617986_18 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 547.0
REGS2_k127_5617986_19 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 555.0
REGS2_k127_5617986_2 AcrB/AcrD/AcrF family - - - 0.0 1127.0
REGS2_k127_5617986_20 PFAM Cys Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 527.0
REGS2_k127_5617986_21 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 531.0
REGS2_k127_5617986_22 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 537.0
REGS2_k127_5617986_23 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 513.0
REGS2_k127_5617986_24 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 495.0
REGS2_k127_5617986_25 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 470.0
REGS2_k127_5617986_26 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 473.0
REGS2_k127_5617986_27 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 456.0
REGS2_k127_5617986_28 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 447.0
REGS2_k127_5617986_29 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 447.0
REGS2_k127_5617986_3 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1063.0
REGS2_k127_5617986_30 amino acid K01999,K11954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 433.0
REGS2_k127_5617986_31 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 419.0
REGS2_k127_5617986_32 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 432.0
REGS2_k127_5617986_33 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 430.0
REGS2_k127_5617986_34 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 409.0
REGS2_k127_5617986_35 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 437.0
REGS2_k127_5617986_36 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 410.0
REGS2_k127_5617986_37 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 415.0
REGS2_k127_5617986_38 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 384.0
REGS2_k127_5617986_39 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 407.0
REGS2_k127_5617986_4 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1058.0
REGS2_k127_5617986_40 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
REGS2_k127_5617986_41 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
REGS2_k127_5617986_42 Aminotransferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 376.0
REGS2_k127_5617986_43 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 372.0
REGS2_k127_5617986_44 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 380.0
REGS2_k127_5617986_45 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 367.0
REGS2_k127_5617986_46 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 351.0
REGS2_k127_5617986_47 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 353.0
REGS2_k127_5617986_48 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 358.0
REGS2_k127_5617986_49 PFAM ABC transporter K10008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 346.0
REGS2_k127_5617986_5 metallopeptidase activity K01993,K13408,K16922 - - 6.617e-253 802.0
REGS2_k127_5617986_50 PFAM O-methyltransferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 339.0
REGS2_k127_5617986_51 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 324.0
REGS2_k127_5617986_52 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 324.0
REGS2_k127_5617986_53 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 324.0
REGS2_k127_5617986_54 thiamine transport K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 317.0
REGS2_k127_5617986_55 SapC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 304.0
REGS2_k127_5617986_56 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 299.0
REGS2_k127_5617986_57 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 307.0
REGS2_k127_5617986_58 NMT1 THI5-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001048 302.0
REGS2_k127_5617986_59 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 287.0
REGS2_k127_5617986_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.877e-231 734.0
REGS2_k127_5617986_60 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006571 281.0
REGS2_k127_5617986_61 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003524 285.0
REGS2_k127_5617986_62 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005587 279.0
REGS2_k127_5617986_63 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009413 266.0
REGS2_k127_5617986_64 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007812 272.0
REGS2_k127_5617986_65 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001383 276.0
REGS2_k127_5617986_66 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001674 276.0
REGS2_k127_5617986_67 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000001416 274.0
REGS2_k127_5617986_68 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003034 273.0
REGS2_k127_5617986_69 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009648 255.0
REGS2_k127_5617986_7 Pfam:DUF1446 - - - 3.676e-218 689.0
REGS2_k127_5617986_70 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002041 270.0
REGS2_k127_5617986_71 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000002462 254.0
REGS2_k127_5617986_72 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000006084 246.0
REGS2_k127_5617986_73 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000001065 233.0
REGS2_k127_5617986_74 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003176 237.0
REGS2_k127_5617986_75 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000006772 242.0
REGS2_k127_5617986_76 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000008242 229.0
REGS2_k127_5617986_77 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000128 228.0
REGS2_k127_5617986_78 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000002382 240.0
REGS2_k127_5617986_79 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000003522 240.0
REGS2_k127_5617986_8 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.555e-207 664.0
REGS2_k127_5617986_80 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.000000000000000000000000000000000000000000000000000000000000007548 226.0
REGS2_k127_5617986_81 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000002788 228.0
REGS2_k127_5617986_82 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000003525 240.0
REGS2_k127_5617986_83 hydrolase activity, acting on ester bonds K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000004565 225.0
REGS2_k127_5617986_84 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000006166 211.0
REGS2_k127_5617986_85 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000008913 210.0
REGS2_k127_5617986_86 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000002742 229.0
REGS2_k127_5617986_87 Thioredoxin-like K02199,K03671 - - 0.00000000000000000000000000000000000000000000000000000001095 216.0
REGS2_k127_5617986_88 Glutamate aspartate transport system permease protein GltJ K02029,K10003 - - 0.00000000000000000000000000000000000000000000000000000003704 204.0
REGS2_k127_5617986_89 transferase activity, transferring glycosyl groups K20444 - - 0.0000000000000000000000000000000000000000000000000000001578 221.0
REGS2_k127_5617986_9 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.919e-204 668.0
REGS2_k127_5617986_90 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000003368 199.0
REGS2_k127_5617986_91 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000001513 190.0
REGS2_k127_5617986_92 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000001612 206.0
REGS2_k127_5617986_93 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000006165 184.0
REGS2_k127_5617986_94 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.0000000000000000000000000000000000000000000000004856 185.0
REGS2_k127_5617986_95 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000000000000000000005763 192.0
REGS2_k127_5617986_96 ABC-type transport system involved in cytochrome c biogenesis, permease component K02194 - - 0.000000000000000000000000000000000000000001463 173.0
REGS2_k127_5617986_97 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001652 164.0
REGS2_k127_5617986_98 4Fe-4S binding domain K05524 - - 0.00000000000000000000000000000000000001117 145.0
REGS2_k127_5617986_99 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000007014 149.0
REGS2_k127_5689933_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 349.0
REGS2_k127_5689933_1 regulatory protein, gntR - - - 0.00000000000000000000000000000000000000000000000000000000000000001802 236.0
REGS2_k127_5689933_2 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000001738 78.0
REGS2_k127_5689933_3 Tetratricopeptide repeat - - - 0.00001671 57.0
REGS2_k127_5817845_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.156e-277 871.0
REGS2_k127_5817845_1 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 3.753e-213 672.0
REGS2_k127_5817845_10 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000125 128.0
REGS2_k127_5817845_11 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000004512 138.0
REGS2_k127_5817845_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 516.0
REGS2_k127_5817845_3 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 472.0
REGS2_k127_5817845_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 440.0
REGS2_k127_5817845_5 Histidine kinase K02668,K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 333.0
REGS2_k127_5817845_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002229 283.0
REGS2_k127_5817845_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000233 215.0
REGS2_k127_5817845_8 Isochorismatase family - - - 0.000000000000000000000000000000000000000003658 161.0
REGS2_k127_5817845_9 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000005469 162.0
REGS2_k127_594452_0 PFAM FAD linked oxidase domain protein - - - 1.356e-300 956.0
REGS2_k127_594452_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 393.0
REGS2_k127_594452_10 thiol-disulfide isomerase and thioredoxins - - - 0.000000000000003307 83.0
REGS2_k127_594452_2 Alcohol dehydrogenase GroES-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 319.0
REGS2_k127_594452_3 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000002531 264.0
REGS2_k127_594452_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.00000000000000000000000000000000000000000000000000009996 193.0
REGS2_k127_594452_5 PFAM ROK family protein K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.0000000000000000000000000000000000000000002125 171.0
REGS2_k127_594452_6 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000000000000000004628 160.0
REGS2_k127_594452_7 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000001378 156.0
REGS2_k127_594452_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000003992 111.0
REGS2_k127_594452_9 Methyltransferase K02493 - 2.1.1.297 0.0000000000000000000001455 106.0
REGS2_k127_5994700_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 466.0
REGS2_k127_5994700_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 447.0
REGS2_k127_5994700_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008522 276.0
REGS2_k127_5994700_3 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000001803 168.0
REGS2_k127_5994700_4 Membrane - - - 0.00000000000000000000000000001321 125.0
REGS2_k127_5994700_5 serine-type endopeptidase activity K04772,K08372 - - 0.000000000000000000000000001446 130.0
REGS2_k127_5994700_6 Protein of unknown function (DUF1344) - - - 0.00006766 51.0
REGS2_k127_6012089_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.949e-277 863.0
REGS2_k127_6012089_1 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 523.0
REGS2_k127_6012089_10 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000004077 216.0
REGS2_k127_6012089_11 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000005175 218.0
REGS2_k127_6012089_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000183 201.0
REGS2_k127_6012089_13 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000000000707 141.0
REGS2_k127_6012089_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000004949 127.0
REGS2_k127_6012089_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000002806 66.0
REGS2_k127_6012089_16 Sporulation related domain - - - 0.00001358 57.0
REGS2_k127_6012089_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 502.0
REGS2_k127_6012089_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 437.0
REGS2_k127_6012089_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 410.0
REGS2_k127_6012089_5 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 362.0
REGS2_k127_6012089_6 TonB-dependent Receptor Plug K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 334.0
REGS2_k127_6012089_7 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000001781 230.0
REGS2_k127_6012089_8 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000007303 235.0
REGS2_k127_6012089_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000001786 229.0
REGS2_k127_6044298_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.08e-205 662.0
REGS2_k127_6044298_1 Efflux ABC transporter, permease ATP-binding protein K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 498.0
REGS2_k127_6044298_10 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000001432 208.0
REGS2_k127_6044298_11 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000002414 194.0
REGS2_k127_6044298_12 - - - - 0.00000000000000000000000000000818 131.0
REGS2_k127_6044298_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 471.0
REGS2_k127_6044298_3 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 419.0
REGS2_k127_6044298_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 340.0
REGS2_k127_6044298_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 299.0
REGS2_k127_6044298_6 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000087 266.0
REGS2_k127_6044298_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002318 276.0
REGS2_k127_6044298_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000006293 247.0
REGS2_k127_6044298_9 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000005335 227.0
REGS2_k127_6060916_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.159e-207 660.0
REGS2_k127_6060916_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 617.0
REGS2_k127_6060916_10 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 331.0
REGS2_k127_6060916_11 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 317.0
REGS2_k127_6060916_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 307.0
REGS2_k127_6060916_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 306.0
REGS2_k127_6060916_14 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002357 260.0
REGS2_k127_6060916_15 COG COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000001197 213.0
REGS2_k127_6060916_16 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000008697 199.0
REGS2_k127_6060916_17 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000535 198.0
REGS2_k127_6060916_18 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000006786 204.0
REGS2_k127_6060916_19 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000001157 168.0
REGS2_k127_6060916_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 557.0
REGS2_k127_6060916_21 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000002707 140.0
REGS2_k127_6060916_22 Crp Fnr family transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000004352 90.0
REGS2_k127_6060916_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000001009 80.0
REGS2_k127_6060916_24 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000005964 81.0
REGS2_k127_6060916_25 transferase activity, transferring glycosyl groups - - - 0.0000000001292 74.0
REGS2_k127_6060916_26 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000001675 64.0
REGS2_k127_6060916_27 - - - - 0.0000000214 55.0
REGS2_k127_6060916_28 zinc metalloprotease K16922 - - 0.00000002679 66.0
REGS2_k127_6060916_29 TonB C terminal K03832 - - 0.00000005747 66.0
REGS2_k127_6060916_3 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 542.0
REGS2_k127_6060916_30 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000002491 55.0
REGS2_k127_6060916_31 septum formation initiator K05589 - - 0.0002013 54.0
REGS2_k127_6060916_4 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 451.0
REGS2_k127_6060916_5 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 441.0
REGS2_k127_6060916_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 428.0
REGS2_k127_6060916_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 402.0
REGS2_k127_6060916_8 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 366.0
REGS2_k127_6060916_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 328.0
REGS2_k127_6086522_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 487.0
REGS2_k127_6086522_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 312.0
REGS2_k127_6086522_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000004669 237.0
REGS2_k127_6086522_3 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000771 132.0
REGS2_k127_6086522_4 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000001985 110.0
REGS2_k127_6097166_0 transmembrane transporter activity K03296 - - 1.377e-318 1010.0
REGS2_k127_6097166_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.655e-218 696.0
REGS2_k127_6097166_10 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 445.0
REGS2_k127_6097166_11 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 431.0
REGS2_k127_6097166_12 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 415.0
REGS2_k127_6097166_13 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 391.0
REGS2_k127_6097166_14 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 372.0
REGS2_k127_6097166_15 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 375.0
REGS2_k127_6097166_16 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 381.0
REGS2_k127_6097166_17 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 364.0
REGS2_k127_6097166_18 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 365.0
REGS2_k127_6097166_19 acyl-CoA dehydrogenase K06446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 366.0
REGS2_k127_6097166_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02487,K03407,K06596 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0019904,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 551.0
REGS2_k127_6097166_20 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 338.0
REGS2_k127_6097166_21 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 355.0
REGS2_k127_6097166_22 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 326.0
REGS2_k127_6097166_23 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 316.0
REGS2_k127_6097166_24 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 305.0
REGS2_k127_6097166_25 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008014 299.0
REGS2_k127_6097166_26 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003097 274.0
REGS2_k127_6097166_27 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002692 280.0
REGS2_k127_6097166_28 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000003388 272.0
REGS2_k127_6097166_29 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003704 287.0
REGS2_k127_6097166_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 526.0
REGS2_k127_6097166_30 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001336 279.0
REGS2_k127_6097166_31 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004284 261.0
REGS2_k127_6097166_32 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006116 262.0
REGS2_k127_6097166_33 PDZ domain (Also known as DHR or GLGF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002322 254.0
REGS2_k127_6097166_34 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000007422 243.0
REGS2_k127_6097166_35 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
REGS2_k127_6097166_36 Methylase of chemotaxis methyl-accepting K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000008716 241.0
REGS2_k127_6097166_37 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000001509 253.0
REGS2_k127_6097166_38 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000522 244.0
REGS2_k127_6097166_39 branched-chain amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000004581 219.0
REGS2_k127_6097166_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 519.0
REGS2_k127_6097166_40 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000002123 227.0
REGS2_k127_6097166_41 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000002097 213.0
REGS2_k127_6097166_42 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000002268 226.0
REGS2_k127_6097166_43 Belongs to the CinA family - - - 0.00000000000000000000000000000000000000000000000000000968 201.0
REGS2_k127_6097166_44 His Kinase A (phosphoacceptor) domain K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000001605 203.0
REGS2_k127_6097166_45 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411,K03412 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000189 190.0
REGS2_k127_6097166_46 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000778 162.0
REGS2_k127_6097166_47 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000001161 174.0
REGS2_k127_6097166_48 Major facilitator Superfamily K02445 - - 0.0000000000000000000000000000000000003208 155.0
REGS2_k127_6097166_49 response regulator receiver K03413 - - 0.0000000000000000000000000000000003433 143.0
REGS2_k127_6097166_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 472.0
REGS2_k127_6097166_50 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000002188 134.0
REGS2_k127_6097166_51 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000003388 128.0
REGS2_k127_6097166_52 Alkylmercury lyase - - - 0.0000000000000000000000000000004087 132.0
REGS2_k127_6097166_53 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000003734 125.0
REGS2_k127_6097166_54 PFAM Tripartite ATP-independent periplasmic transporter DctQ component K11689 - - 0.000000000000000000000000009726 118.0
REGS2_k127_6097166_55 Outer membrane efflux protein - - - 0.0000000000001117 84.0
REGS2_k127_6097166_56 belongs to the thioredoxin family - - - 0.00000000003296 74.0
REGS2_k127_6097166_57 - - - - 0.0000000007585 70.0
REGS2_k127_6097166_59 NMT1-like family K02051 - - 0.000000416 62.0
REGS2_k127_6097166_6 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 476.0
REGS2_k127_6097166_61 archaeal or bacterial-type flagellum-dependent cell motility K03414 - - 0.000007705 56.0
REGS2_k127_6097166_62 Lipopolysaccharide assembly protein A domain K08992 - - 0.00001857 51.0
REGS2_k127_6097166_63 - - - - 0.0002835 49.0
REGS2_k127_6097166_7 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 478.0
REGS2_k127_6097166_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 442.0
REGS2_k127_6097166_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 453.0
REGS2_k127_6107099_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2288.0
REGS2_k127_6107099_1 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 8.628e-255 797.0
REGS2_k127_6107099_10 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 432.0
REGS2_k127_6107099_11 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 429.0
REGS2_k127_6107099_12 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 414.0
REGS2_k127_6107099_13 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 423.0
REGS2_k127_6107099_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 386.0
REGS2_k127_6107099_15 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 417.0
REGS2_k127_6107099_16 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 361.0
REGS2_k127_6107099_17 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 348.0
REGS2_k127_6107099_18 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 325.0
REGS2_k127_6107099_19 COG0583 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003906 282.0
REGS2_k127_6107099_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.221e-252 802.0
REGS2_k127_6107099_20 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001719 268.0
REGS2_k127_6107099_21 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005563 277.0
REGS2_k127_6107099_22 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000003459 264.0
REGS2_k127_6107099_23 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002219 255.0
REGS2_k127_6107099_24 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005317 244.0
REGS2_k127_6107099_25 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000006249 241.0
REGS2_k127_6107099_26 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
REGS2_k127_6107099_27 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000129 190.0
REGS2_k127_6107099_28 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000005949 170.0
REGS2_k127_6107099_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000006072 154.0
REGS2_k127_6107099_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.288e-235 742.0
REGS2_k127_6107099_30 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000000008556 154.0
REGS2_k127_6107099_31 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000153 143.0
REGS2_k127_6107099_32 LUD domain K00782,K18929 - - 0.00000000000000000000002242 115.0
REGS2_k127_6107099_33 CBS domain - - - 0.0000000000000000001162 103.0
REGS2_k127_6107099_34 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000001597 99.0
REGS2_k127_6107099_35 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000004335 89.0
REGS2_k127_6107099_36 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.0000000000000002873 89.0
REGS2_k127_6107099_37 - - - - 0.0000002101 55.0
REGS2_k127_6107099_38 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 0.000001612 51.0
REGS2_k127_6107099_4 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 604.0
REGS2_k127_6107099_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 608.0
REGS2_k127_6107099_6 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 540.0
REGS2_k127_6107099_7 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 510.0
REGS2_k127_6107099_8 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 481.0
REGS2_k127_6107099_9 Domain of unknown function (DUF3390) K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 471.0
REGS2_k127_618176_0 (ABC) transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008608 254.0
REGS2_k127_618176_1 xanthine dehydrogenase activity K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000001353 252.0
REGS2_k127_618176_2 rRNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001326 241.0
REGS2_k127_618176_3 Thioredoxin - - - 0.00000001079 65.0
REGS2_k127_6210952_0 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 328.0
REGS2_k127_6210952_1 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000016 284.0
REGS2_k127_6210952_2 Carbonic anhydrase - - - 0.00000000000000000000000000000000000000000000000000000000007366 209.0
REGS2_k127_6210952_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000004174 154.0
REGS2_k127_6210952_4 N-terminal half of MaoC dehydratase - - - 0.000000000000001895 78.0
REGS2_k127_6361247_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.309e-297 924.0
REGS2_k127_6361247_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.884e-255 824.0
REGS2_k127_6361247_10 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 630.0
REGS2_k127_6361247_100 PFAM THUMP domain protein K06963 - - 0.000000000000008155 87.0
REGS2_k127_6361247_101 Uncharacterized conserved protein (DUF2267) - - - 0.00000000000003036 84.0
REGS2_k127_6361247_102 Glycosyl transferase, family 2 - - - 0.000000000001305 70.0
REGS2_k127_6361247_103 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000004568 74.0
REGS2_k127_6361247_104 Dehydrogenase K03519 - 1.2.5.3 0.0000001387 57.0
REGS2_k127_6361247_105 conserved protein (DUF2267) - - - 0.0000001995 58.0
REGS2_k127_6361247_106 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000007958 57.0
REGS2_k127_6361247_107 - - - - 0.00008226 45.0
REGS2_k127_6361247_109 Phosphatidylethanolamine-binding protein K06910 - - 0.000729 44.0
REGS2_k127_6361247_11 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 614.0
REGS2_k127_6361247_12 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 606.0
REGS2_k127_6361247_13 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 600.0
REGS2_k127_6361247_14 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 608.0
REGS2_k127_6361247_15 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 575.0
REGS2_k127_6361247_16 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 536.0
REGS2_k127_6361247_17 PFAM Hydantoinase B oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 550.0
REGS2_k127_6361247_18 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 511.0
REGS2_k127_6361247_19 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 492.0
REGS2_k127_6361247_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.079e-239 750.0
REGS2_k127_6361247_20 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
REGS2_k127_6361247_21 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 492.0
REGS2_k127_6361247_22 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 482.0
REGS2_k127_6361247_23 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 482.0
REGS2_k127_6361247_24 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 464.0
REGS2_k127_6361247_25 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 453.0
REGS2_k127_6361247_26 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 448.0
REGS2_k127_6361247_27 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 448.0
REGS2_k127_6361247_28 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 432.0
REGS2_k127_6361247_29 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 431.0
REGS2_k127_6361247_3 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 1.606e-234 750.0
REGS2_k127_6361247_30 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 416.0
REGS2_k127_6361247_31 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 409.0
REGS2_k127_6361247_32 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 396.0
REGS2_k127_6361247_33 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 413.0
REGS2_k127_6361247_34 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 390.0
REGS2_k127_6361247_35 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 385.0
REGS2_k127_6361247_36 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 374.0
REGS2_k127_6361247_37 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 374.0
REGS2_k127_6361247_38 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 373.0
REGS2_k127_6361247_39 COGs COG0616 Periplasmic serine protease (ClpP class) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 354.0
REGS2_k127_6361247_4 DNA polymerase X family K02347,K04477 - - 3.459e-230 730.0
REGS2_k127_6361247_40 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 352.0
REGS2_k127_6361247_41 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 338.0
REGS2_k127_6361247_42 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 360.0
REGS2_k127_6361247_43 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 332.0
REGS2_k127_6361247_44 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 314.0
REGS2_k127_6361247_45 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 305.0
REGS2_k127_6361247_46 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 300.0
REGS2_k127_6361247_47 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 289.0
REGS2_k127_6361247_48 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 288.0
REGS2_k127_6361247_49 COG0006 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002346 292.0
REGS2_k127_6361247_5 Phosphate acyltransferases - - - 3.434e-226 773.0
REGS2_k127_6361247_50 Formate/nitrite transporter K06212 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 280.0
REGS2_k127_6361247_51 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007057 290.0
REGS2_k127_6361247_52 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000144 272.0
REGS2_k127_6361247_53 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002343 278.0
REGS2_k127_6361247_54 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004582 271.0
REGS2_k127_6361247_55 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002796 271.0
REGS2_k127_6361247_56 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 267.0
REGS2_k127_6361247_57 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 273.0
REGS2_k127_6361247_58 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000002602 273.0
REGS2_k127_6361247_59 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002889 248.0
REGS2_k127_6361247_6 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 6.876e-224 736.0
REGS2_k127_6361247_60 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000002236 257.0
REGS2_k127_6361247_61 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000004097 240.0
REGS2_k127_6361247_62 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000005453 254.0
REGS2_k127_6361247_63 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000001155 240.0
REGS2_k127_6361247_64 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000289 242.0
REGS2_k127_6361247_65 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000004002 229.0
REGS2_k127_6361247_66 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000003881 219.0
REGS2_k127_6361247_67 - - - - 0.00000000000000000000000000000000000000000000000000000000000009721 225.0
REGS2_k127_6361247_68 Methylmalonyl-CoA mutase K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000003256 206.0
REGS2_k127_6361247_69 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000001614 193.0
REGS2_k127_6361247_7 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 5.357e-218 691.0
REGS2_k127_6361247_70 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000008557 184.0
REGS2_k127_6361247_71 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000001645 183.0
REGS2_k127_6361247_72 Pfam:AHS1 - - - 0.000000000000000000000000000000000000000000000945 179.0
REGS2_k127_6361247_73 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000002112 175.0
REGS2_k127_6361247_74 UTRA K03710 - - 0.000000000000000000000000000000000000000001205 166.0
REGS2_k127_6361247_75 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000002585 166.0
REGS2_k127_6361247_76 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000001532 149.0
REGS2_k127_6361247_77 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000003469 146.0
REGS2_k127_6361247_78 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000003715 150.0
REGS2_k127_6361247_79 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000000000000000000006845 138.0
REGS2_k127_6361247_8 Belongs to the peptidase S16 family - - - 3.364e-216 700.0
REGS2_k127_6361247_80 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000219 138.0
REGS2_k127_6361247_81 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000005072 133.0
REGS2_k127_6361247_82 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000002875 133.0
REGS2_k127_6361247_83 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000007453 143.0
REGS2_k127_6361247_84 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000353 129.0
REGS2_k127_6361247_85 Putative nucleotidyltransferase substrate binding domain - - - 0.00000000000000000000000000002475 121.0
REGS2_k127_6361247_86 GntR family transcriptional regulator K03486,K03710 - - 0.00000000000000000000000000004848 125.0
REGS2_k127_6361247_87 GYD domain - - - 0.0000000000000000000000000001274 119.0
REGS2_k127_6361247_88 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000001899 120.0
REGS2_k127_6361247_89 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000006403 123.0
REGS2_k127_6361247_9 Belongs to the RtcB family K14415 - 6.5.1.3 2.165e-204 647.0
REGS2_k127_6361247_90 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000003194 110.0
REGS2_k127_6361247_91 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000001716 110.0
REGS2_k127_6361247_92 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000000000000000000002837 118.0
REGS2_k127_6361247_93 Universal stress protein family - - - 0.000000000000000000000003687 109.0
REGS2_k127_6361247_94 PFAM CBS domain containing protein K04767 - - 0.000000000000000000005373 104.0
REGS2_k127_6361247_95 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000154 91.0
REGS2_k127_6361247_96 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000002022 98.0
REGS2_k127_6361247_97 Universal stress protein family - - - 0.0000000000000006517 89.0
REGS2_k127_6361247_98 Phosphopantetheine attachment site - - - 0.000000000000001305 90.0
REGS2_k127_6361247_99 Protein of unknown function (DUF3175) - - - 0.000000000000004585 85.0
REGS2_k127_6519263_0 GTP-binding protein TypA K06207 - - 3.408e-253 796.0
REGS2_k127_6519263_1 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 1.279e-247 786.0
REGS2_k127_6519263_10 PFAM Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000002149 241.0
REGS2_k127_6519263_11 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000002181 224.0
REGS2_k127_6519263_12 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000002348 190.0
REGS2_k127_6519263_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000007554 189.0
REGS2_k127_6519263_14 Putative outer membrane beta-barrel porin, MtrB/PioB K22110 - - 0.000000000000000000000000000000000000000000000006471 196.0
REGS2_k127_6519263_15 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.0000000000000000000000000000000000007427 146.0
REGS2_k127_6519263_16 quinone binding K12057,K22278 - 3.5.1.104 0.000000000000000000000000009302 118.0
REGS2_k127_6519263_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000004998 109.0
REGS2_k127_6519263_18 - K06039 - - 0.000000000000000000001611 109.0
REGS2_k127_6519263_19 Cytochrome c K17222 - - 0.0000000000000000002846 101.0
REGS2_k127_6519263_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 438.0
REGS2_k127_6519263_20 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000003173 96.0
REGS2_k127_6519263_21 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000001644 86.0
REGS2_k127_6519263_23 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000003665 93.0
REGS2_k127_6519263_24 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000007013 59.0
REGS2_k127_6519263_25 Protein of unknown function (DUF465) - - - 0.000004131 53.0
REGS2_k127_6519263_26 PIN domain K18828 - - 0.00002414 53.0
REGS2_k127_6519263_3 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 363.0
REGS2_k127_6519263_4 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
REGS2_k127_6519263_5 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 325.0
REGS2_k127_6519263_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 338.0
REGS2_k127_6519263_7 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 325.0
REGS2_k127_6519263_8 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 316.0
REGS2_k127_6519263_9 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 289.0
REGS2_k127_6732664_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.266e-223 702.0
REGS2_k127_6732664_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
REGS2_k127_6732664_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 442.0
REGS2_k127_6732664_3 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 314.0
REGS2_k127_6732664_4 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
REGS2_k127_6732664_6 nickel cation binding K03190 - - 0.000000000000000000000000002906 124.0
REGS2_k127_6912901_0 mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 530.0
REGS2_k127_6912901_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 505.0
REGS2_k127_6912901_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 490.0
REGS2_k127_6912901_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 461.0
REGS2_k127_6912901_4 Belongs to the DapA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
REGS2_k127_6912901_5 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000008516 214.0
REGS2_k127_6912901_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000006995 205.0
REGS2_k127_6912901_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124,K07307 - - 0.000000000000000000000000000000000000000000002184 169.0
REGS2_k127_6912901_8 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000003725 99.0
REGS2_k127_6923057_0 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 2.282e-227 754.0
REGS2_k127_6923057_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 3.873e-227 734.0
REGS2_k127_6923057_2 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 519.0
REGS2_k127_6923057_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 419.0
REGS2_k127_6923057_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
REGS2_k127_6923057_5 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002648 282.0
REGS2_k127_6923057_6 AroM protein - - - 0.00000000000000000000000000000000000000000000000135 181.0
REGS2_k127_6923057_7 PFAM YCII-related domain K09780 - - 0.00000003045 62.0
REGS2_k127_6923057_8 OsmC-like protein - - - 0.00001213 51.0
REGS2_k127_6923057_9 - - - - 0.0003067 53.0
REGS2_k127_6953014_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1075.0
REGS2_k127_6953014_1 Multicopper oxidase K06324 - 1.16.3.3 3.666e-244 777.0
REGS2_k127_6953014_10 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 474.0
REGS2_k127_6953014_11 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 488.0
REGS2_k127_6953014_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
REGS2_k127_6953014_13 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 405.0
REGS2_k127_6953014_14 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 394.0
REGS2_k127_6953014_15 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 378.0
REGS2_k127_6953014_16 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 358.0
REGS2_k127_6953014_17 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 358.0
REGS2_k127_6953014_18 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 368.0
REGS2_k127_6953014_19 Amidohydrolase family K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 362.0
REGS2_k127_6953014_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.356e-240 755.0
REGS2_k127_6953014_20 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 350.0
REGS2_k127_6953014_21 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 346.0
REGS2_k127_6953014_22 Ethanolamine utilization protein EutJ K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 321.0
REGS2_k127_6953014_23 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 325.0
REGS2_k127_6953014_24 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 319.0
REGS2_k127_6953014_25 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 309.0
REGS2_k127_6953014_26 the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 297.0
REGS2_k127_6953014_27 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 294.0
REGS2_k127_6953014_28 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 291.0
REGS2_k127_6953014_29 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
REGS2_k127_6953014_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 586.0
REGS2_k127_6953014_30 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001678 289.0
REGS2_k127_6953014_31 Asp Glu hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000433 270.0
REGS2_k127_6953014_32 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007586 276.0
REGS2_k127_6953014_33 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003128 274.0
REGS2_k127_6953014_34 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006356 256.0
REGS2_k127_6953014_35 branched-chain amino acid ABC transporter ATP-binding protein K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
REGS2_k127_6953014_36 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002771 256.0
REGS2_k127_6953014_37 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007216 259.0
REGS2_k127_6953014_38 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000009562 247.0
REGS2_k127_6953014_39 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000289 239.0
REGS2_k127_6953014_4 Gamma-glutamyltranspeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 574.0
REGS2_k127_6953014_40 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 243.0
REGS2_k127_6953014_41 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003593 252.0
REGS2_k127_6953014_42 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000004568 240.0
REGS2_k127_6953014_43 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005507 221.0
REGS2_k127_6953014_44 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000001091 219.0
REGS2_k127_6953014_45 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000007205 212.0
REGS2_k127_6953014_46 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000001043 202.0
REGS2_k127_6953014_47 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000008928 209.0
REGS2_k127_6953014_48 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K07010 - - 0.0000000000000000000000000000000000000000000000000003795 203.0
REGS2_k127_6953014_49 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000009379 183.0
REGS2_k127_6953014_5 histidine kinase, HAMP K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 556.0
REGS2_k127_6953014_50 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000003597 184.0
REGS2_k127_6953014_51 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000002409 164.0
REGS2_k127_6953014_52 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000002687 149.0
REGS2_k127_6953014_53 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000634 146.0
REGS2_k127_6953014_54 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.000000000000000000000000000005758 130.0
REGS2_k127_6953014_55 - - - - 0.00000000000000000000000000006553 123.0
REGS2_k127_6953014_56 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000001738 123.0
REGS2_k127_6953014_57 Thioesterase-like superfamily K01075 - 3.1.2.23 0.0000000000000000000000002604 115.0
REGS2_k127_6953014_58 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000103 97.0
REGS2_k127_6953014_59 - - - - 0.00000000000000000001529 96.0
REGS2_k127_6953014_6 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 530.0
REGS2_k127_6953014_60 Trm112p-like protein K09791 - - 0.0000000003417 72.0
REGS2_k127_6953014_61 Abc-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000004451 64.0
REGS2_k127_6953014_62 Domain of unknown function (DUF4390) - - - 0.0000003261 59.0
REGS2_k127_6953014_63 CoA-ligase K02381 - - 0.0000006101 62.0
REGS2_k127_6953014_64 FecR protein - - - 0.000002589 60.0
REGS2_k127_6953014_65 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0003186 52.0
REGS2_k127_6953014_66 Archease protein family (MTH1598/TM1083) - - - 0.0005033 50.0
REGS2_k127_6953014_7 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 484.0
REGS2_k127_6953014_8 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 491.0
REGS2_k127_6953014_9 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 487.0
REGS2_k127_6975568_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.566e-247 778.0
REGS2_k127_6975568_1 General secretory system II protein E domain protein - - - 7.053e-243 772.0
REGS2_k127_6975568_10 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 412.0
REGS2_k127_6975568_11 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 395.0
REGS2_k127_6975568_12 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 299.0
REGS2_k127_6975568_13 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001574 263.0
REGS2_k127_6975568_14 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000466 242.0
REGS2_k127_6975568_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001031 242.0
REGS2_k127_6975568_16 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000000000000000000000003625 184.0
REGS2_k127_6975568_17 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000001262 158.0
REGS2_k127_6975568_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000969 140.0
REGS2_k127_6975568_19 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000004811 79.0
REGS2_k127_6975568_2 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 1.71e-240 773.0
REGS2_k127_6975568_20 Protein conserved in bacteria - - - 0.0000000000006471 73.0
REGS2_k127_6975568_21 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000002517 66.0
REGS2_k127_6975568_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 2.314e-202 641.0
REGS2_k127_6975568_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 625.0
REGS2_k127_6975568_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 579.0
REGS2_k127_6975568_6 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 561.0
REGS2_k127_6975568_7 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 549.0
REGS2_k127_6975568_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 536.0
REGS2_k127_6975568_9 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 412.0
REGS2_k127_6992762_0 Binding-protein-dependent transport system inner membrane component - - - 1.754e-212 676.0
REGS2_k127_6992762_1 AMP-binding enzyme C-terminal domain - - - 2.635e-212 671.0
REGS2_k127_6992762_10 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001328 250.0
REGS2_k127_6992762_11 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000001637 251.0
REGS2_k127_6992762_12 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000008254 226.0
REGS2_k127_6992762_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000137 231.0
REGS2_k127_6992762_14 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000003736 216.0
REGS2_k127_6992762_15 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000009211 211.0
REGS2_k127_6992762_16 Phosphonate ABC transporter K02044 - - 0.000000000000000000000000000000000000000000002167 190.0
REGS2_k127_6992762_17 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000123 152.0
REGS2_k127_6992762_18 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000003652 123.0
REGS2_k127_6992762_19 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000001396 98.0
REGS2_k127_6992762_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 623.0
REGS2_k127_6992762_3 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 459.0
REGS2_k127_6992762_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 474.0
REGS2_k127_6992762_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 431.0
REGS2_k127_6992762_6 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 330.0
REGS2_k127_6992762_7 thiamine-containing compound biosynthetic process K02051,K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002847 298.0
REGS2_k127_6992762_8 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000178 269.0
REGS2_k127_6992762_9 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000257 271.0
REGS2_k127_7002367_0 Belongs to the glycosyl hydrolase 57 family - - - 2.261e-212 693.0
REGS2_k127_7002367_1 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 589.0
REGS2_k127_7002367_2 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 514.0
REGS2_k127_7002367_3 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 496.0
REGS2_k127_7002367_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 475.0
REGS2_k127_7002367_5 PFAM Glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000538 203.0
REGS2_k127_7002367_6 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000000000000000000000000002397 179.0
REGS2_k127_7002367_7 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0000000000000000000000000001363 132.0
REGS2_k127_7002367_9 Pfam:DUF461 K09796 - - 0.0009697 52.0
REGS2_k127_7017300_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 629.0
REGS2_k127_7017300_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 580.0
REGS2_k127_7017300_10 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 474.0
REGS2_k127_7017300_11 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 452.0
REGS2_k127_7017300_12 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 440.0
REGS2_k127_7017300_13 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 428.0
REGS2_k127_7017300_14 carbamoyl transferase, NodU family K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 437.0
REGS2_k127_7017300_15 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 420.0
REGS2_k127_7017300_16 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 407.0
REGS2_k127_7017300_17 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 391.0
REGS2_k127_7017300_18 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 389.0
REGS2_k127_7017300_19 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 385.0
REGS2_k127_7017300_2 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 564.0
REGS2_k127_7017300_20 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 394.0
REGS2_k127_7017300_21 Belongs to the D-glutamate cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 351.0
REGS2_k127_7017300_22 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 350.0
REGS2_k127_7017300_23 acid synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 347.0
REGS2_k127_7017300_24 ABC transporter K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 349.0
REGS2_k127_7017300_25 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 332.0
REGS2_k127_7017300_26 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 358.0
REGS2_k127_7017300_27 Competence protein ComEC K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 349.0
REGS2_k127_7017300_28 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 323.0
REGS2_k127_7017300_29 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 321.0
REGS2_k127_7017300_3 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 559.0
REGS2_k127_7017300_30 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 296.0
REGS2_k127_7017300_31 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 287.0
REGS2_k127_7017300_32 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 285.0
REGS2_k127_7017300_33 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009384 283.0
REGS2_k127_7017300_34 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 275.0
REGS2_k127_7017300_35 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009967 265.0
REGS2_k127_7017300_36 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 260.0
REGS2_k127_7017300_38 Spore coat polysaccharide biosynthesis protein K07257 - - 0.000000000000000000000000000000000000000000000000000000000000000000002814 252.0
REGS2_k127_7017300_39 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000004498 259.0
REGS2_k127_7017300_4 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 531.0
REGS2_k127_7017300_40 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000006612 240.0
REGS2_k127_7017300_41 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000001998 233.0
REGS2_k127_7017300_42 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000001677 226.0
REGS2_k127_7017300_43 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000006315 226.0
REGS2_k127_7017300_44 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000003501 209.0
REGS2_k127_7017300_45 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000001174 215.0
REGS2_k127_7017300_46 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000009553 217.0
REGS2_k127_7017300_47 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000221 193.0
REGS2_k127_7017300_48 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000009051 171.0
REGS2_k127_7017300_49 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000003594 166.0
REGS2_k127_7017300_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 513.0
REGS2_k127_7017300_50 PFAM peptidase - - - 0.000000000000000000000000000000000000000000004623 175.0
REGS2_k127_7017300_51 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000007836 186.0
REGS2_k127_7017300_52 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000007035 169.0
REGS2_k127_7017300_53 Sigma-70, region 4 K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000005876 153.0
REGS2_k127_7017300_55 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000001059 152.0
REGS2_k127_7017300_56 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000001617 145.0
REGS2_k127_7017300_57 Transposase - - - 0.0000000000000000000000000000000007151 136.0
REGS2_k127_7017300_58 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000001717 139.0
REGS2_k127_7017300_59 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000001106 129.0
REGS2_k127_7017300_6 Bacterial sugar transferase K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 506.0
REGS2_k127_7017300_60 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000004328 137.0
REGS2_k127_7017300_61 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000005552 127.0
REGS2_k127_7017300_62 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000003206 133.0
REGS2_k127_7017300_63 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000008977 111.0
REGS2_k127_7017300_65 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000001278 113.0
REGS2_k127_7017300_66 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000002498 116.0
REGS2_k127_7017300_67 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001067 103.0
REGS2_k127_7017300_68 Bacterial transferase hexapeptide (six repeats) K00638,K18234 - 2.3.1.28 0.000000000000000000000979 109.0
REGS2_k127_7017300_69 Periplasmic or secreted lipoprotein - - - 0.000000000000000000001767 95.0
REGS2_k127_7017300_7 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 496.0
REGS2_k127_7017300_70 O-Antigen ligase K18814 - - 0.00000000000000000001164 106.0
REGS2_k127_7017300_71 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000003677 97.0
REGS2_k127_7017300_72 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.000000000000000001191 94.0
REGS2_k127_7017300_73 radical SAM domain protein K21551 - 2.1.1.106 0.000000000000000002303 101.0
REGS2_k127_7017300_74 protein-(glutamine-N5) methyltransferase activity K16868,K18896 - 2.1.1.156,2.1.1.265 0.00000000000000006021 93.0
REGS2_k127_7017300_75 methyltransferase - - - 0.0000000000000007972 87.0
REGS2_k127_7017300_76 Glycosyl transferase 4-like domain - - - 0.000000000000002817 88.0
REGS2_k127_7017300_77 TIGRFAM competence protein ComEA K02237 - - 0.0000000000006883 76.0
REGS2_k127_7017300_78 Fibronectin type 3 domain - - - 0.0000000001614 74.0
REGS2_k127_7017300_79 Methyltransferase domain - - - 0.0002248 52.0
REGS2_k127_7017300_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 488.0
REGS2_k127_7017300_80 pseudaminic acid biosynthesis-associated protein PseG - - - 0.0002679 52.0
REGS2_k127_7017300_9 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 474.0
REGS2_k127_7026889_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 4.903e-312 970.0
REGS2_k127_7026889_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 404.0
REGS2_k127_7026889_10 PFAM Tetratricopeptide TPR_2 repeat protein - - - 0.00004585 53.0
REGS2_k127_7026889_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003865 272.0
REGS2_k127_7026889_3 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000001671 233.0
REGS2_k127_7026889_4 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000005173 224.0
REGS2_k127_7026889_5 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001667 208.0
REGS2_k127_7026889_6 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000001235 145.0
REGS2_k127_7026889_7 Transcriptional regulator - - - 0.00000000000000000000002277 112.0
REGS2_k127_7026889_8 Polymer-forming cytoskeletal - - - 0.000000000000000000002029 102.0
REGS2_k127_7026889_9 PFAM coenzyme A transferase K01039 - 2.8.3.12 0.00000000002227 70.0
REGS2_k127_7077095_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000839 293.0
REGS2_k127_7077095_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002658 268.0
REGS2_k127_7077095_10 acyl carrier protein K02078 - - 0.00000003783 59.0
REGS2_k127_7077095_11 synthase K09458 - 2.3.1.179 0.000002065 60.0
REGS2_k127_7077095_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000003239 250.0
REGS2_k127_7077095_3 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000007477 238.0
REGS2_k127_7077095_4 glycosyl transferase - - - 0.00000000000000000000000000000000000000001048 169.0
REGS2_k127_7077095_5 ABC transporter K02003,K02004 - - 0.0000000000000000000000000000002098 131.0
REGS2_k127_7077095_6 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000003212 120.0
REGS2_k127_7077095_8 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000004623 113.0
REGS2_k127_7077095_9 MacB-like periplasmic core domain K02004 - - 0.0000000000000001048 93.0
REGS2_k127_713900_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.005e-266 840.0
REGS2_k127_713900_1 ABC-type dipeptide transport system periplasmic component K02035 - - 1.858e-257 802.0
REGS2_k127_713900_10 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 364.0
REGS2_k127_713900_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 306.0
REGS2_k127_713900_12 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
REGS2_k127_713900_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007356 279.0
REGS2_k127_713900_14 NADPH quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001699 252.0
REGS2_k127_713900_15 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000000000164 224.0
REGS2_k127_713900_16 KR domain K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000004498 206.0
REGS2_k127_713900_17 ribonucleoside-diphosphate reductase activity K07735 - - 0.0000000000000000000000000000000000000000000000000000001568 207.0
REGS2_k127_713900_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000004122 208.0
REGS2_k127_713900_19 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000004364 205.0
REGS2_k127_713900_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 8.39e-209 662.0
REGS2_k127_713900_20 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000001741 194.0
REGS2_k127_713900_21 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000005459 179.0
REGS2_k127_713900_22 Haem-degrading - - - 0.000000000000000000000000000000000000000001094 160.0
REGS2_k127_713900_23 diguanylate cyclase - - - 0.00000000000000000000000000000000000002424 157.0
REGS2_k127_713900_24 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000001074 141.0
REGS2_k127_713900_25 iron dependent repressor K03709 - - 0.00000000000000000000000000000001672 135.0
REGS2_k127_713900_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 612.0
REGS2_k127_713900_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 590.0
REGS2_k127_713900_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 473.0
REGS2_k127_713900_6 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 445.0
REGS2_k127_713900_7 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 426.0
REGS2_k127_713900_8 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 407.0
REGS2_k127_713900_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 389.0
REGS2_k127_7157091_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 1.334e-238 753.0
REGS2_k127_7157091_1 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 502.0
REGS2_k127_7157091_10 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001624 297.0
REGS2_k127_7157091_11 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000002557 233.0
REGS2_k127_7157091_12 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
REGS2_k127_7157091_13 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000004873 204.0
REGS2_k127_7157091_14 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000000000000000000000000000001205 191.0
REGS2_k127_7157091_16 dehydratase - - - 0.00000000000000000000000000000000000000000000005421 181.0
REGS2_k127_7157091_17 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000001577 165.0
REGS2_k127_7157091_18 - - - - 0.0000000000000000000000000001811 126.0
REGS2_k127_7157091_19 cold-shock protein K03704 - - 0.000000000000000000000000005466 117.0
REGS2_k127_7157091_2 lyase activity K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 496.0
REGS2_k127_7157091_20 Membrane - - - 0.000000000000000000001023 108.0
REGS2_k127_7157091_21 DinB superfamily - - - 0.000000000000005372 82.0
REGS2_k127_7157091_22 glycogen debranching - - - 0.0000005439 53.0
REGS2_k127_7157091_23 DinB superfamily - - - 0.000004835 58.0
REGS2_k127_7157091_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 492.0
REGS2_k127_7157091_4 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 384.0
REGS2_k127_7157091_5 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 372.0
REGS2_k127_7157091_6 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 321.0
REGS2_k127_7157091_7 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 297.0
REGS2_k127_7157091_8 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001078 293.0
REGS2_k127_7157091_9 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001227 293.0
REGS2_k127_7219019_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 2.619e-221 708.0
REGS2_k127_7219019_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 642.0
REGS2_k127_7219019_10 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000005972 258.0
REGS2_k127_7219019_11 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
REGS2_k127_7219019_12 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005707 218.0
REGS2_k127_7219019_13 COGs COG1801 conserved - - - 0.0000000000000000000000000000000000000000000000000000000002414 220.0
REGS2_k127_7219019_14 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000003238 184.0
REGS2_k127_7219019_15 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000006523 202.0
REGS2_k127_7219019_16 GDP-mannose mannosyl hydrolase activity K18445 - 3.6.1.61 0.00000000000000000000000000000000000000000003583 164.0
REGS2_k127_7219019_17 PFAM Alpha beta hydrolase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000002522 154.0
REGS2_k127_7219019_18 spore germination - - - 0.00000000000000000000000000000000005208 139.0
REGS2_k127_7219019_19 Metal binding domain of Ada K00567 - 2.1.1.63 0.0000000000000000000000000000004234 140.0
REGS2_k127_7219019_2 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 608.0
REGS2_k127_7219019_20 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000007939 135.0
REGS2_k127_7219019_21 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000009808 135.0
REGS2_k127_7219019_22 Rhodanese Homology Domain - - - 0.000000000000000000000005796 107.0
REGS2_k127_7219019_23 dehydratase K01724 - 4.2.1.96 0.0000000000000000000003366 100.0
REGS2_k127_7219019_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000009395 98.0
REGS2_k127_7219019_26 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000002188 92.0
REGS2_k127_7219019_27 Glycosyl transferase family 2 - - - 0.000000000000007397 77.0
REGS2_k127_7219019_28 COG1073 Hydrolases of the alpha beta superfamily K06889,K07397 - - 0.000000001775 61.0
REGS2_k127_7219019_29 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.000000004815 67.0
REGS2_k127_7219019_3 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 554.0
REGS2_k127_7219019_30 Transglycosylase SLT domain K08309 - - 0.000003813 58.0
REGS2_k127_7219019_31 OsmC-like protein - - - 0.00001003 50.0
REGS2_k127_7219019_4 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 471.0
REGS2_k127_7219019_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 387.0
REGS2_k127_7219019_6 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 334.0
REGS2_k127_7219019_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 325.0
REGS2_k127_7219019_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 301.0
REGS2_k127_7219019_9 ATP-dependent helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005469 289.0
REGS2_k127_7220817_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 454.0
REGS2_k127_7220817_1 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002898 284.0
REGS2_k127_7220817_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000145 163.0
REGS2_k127_7220817_3 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000003172 123.0
REGS2_k127_7220817_4 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000004368 89.0
REGS2_k127_7220817_5 - - - - 0.0000008643 60.0
REGS2_k127_7341046_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.0 1223.0
REGS2_k127_7341046_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 566.0
REGS2_k127_7341046_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 426.0
REGS2_k127_7341046_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 420.0
REGS2_k127_7341046_12 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 419.0
REGS2_k127_7341046_13 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 411.0
REGS2_k127_7341046_14 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 391.0
REGS2_k127_7341046_15 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 379.0
REGS2_k127_7341046_16 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 369.0
REGS2_k127_7341046_17 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 357.0
REGS2_k127_7341046_18 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 359.0
REGS2_k127_7341046_19 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 329.0
REGS2_k127_7341046_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 507.0
REGS2_k127_7341046_20 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
REGS2_k127_7341046_21 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 299.0
REGS2_k127_7341046_22 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 315.0
REGS2_k127_7341046_23 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003147 284.0
REGS2_k127_7341046_24 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001985 286.0
REGS2_k127_7341046_25 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 274.0
REGS2_k127_7341046_26 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000009512 208.0
REGS2_k127_7341046_27 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000004485 224.0
REGS2_k127_7341046_28 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000002779 196.0
REGS2_k127_7341046_29 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000003231 165.0
REGS2_k127_7341046_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 514.0
REGS2_k127_7341046_30 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000001008 172.0
REGS2_k127_7341046_31 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000003309 153.0
REGS2_k127_7341046_32 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000000000000000000000000000009971 149.0
REGS2_k127_7341046_33 YGGT family K02221 - - 0.000000000000000000000000000001086 123.0
REGS2_k127_7341046_34 RF-1 domain K15034 - - 0.00000000000000000000000000003108 123.0
REGS2_k127_7341046_35 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000001754 120.0
REGS2_k127_7341046_36 PFAM DivIVA family protein K04074 - - 0.000000000000000000000003372 108.0
REGS2_k127_7341046_37 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000002904 110.0
REGS2_k127_7341046_38 DUF167 K09131 - - 0.00000000000000005256 84.0
REGS2_k127_7341046_39 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000007674 86.0
REGS2_k127_7341046_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 496.0
REGS2_k127_7341046_40 Cell division protein FtsQ K03589 - - 0.000000000000009763 85.0
REGS2_k127_7341046_41 YacP-like NYN domain K06962 - - 0.0000000000002715 77.0
REGS2_k127_7341046_42 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000002514 78.0
REGS2_k127_7341046_43 pilus assembly protein PilW K02672 - - 0.00000009658 61.0
REGS2_k127_7341046_44 - - - - 0.000008071 55.0
REGS2_k127_7341046_46 Peptidase family M48 - - - 0.0007585 46.0
REGS2_k127_7341046_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 483.0
REGS2_k127_7341046_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 471.0
REGS2_k127_7341046_7 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 468.0
REGS2_k127_7341046_8 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 446.0
REGS2_k127_7341046_9 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 442.0
REGS2_k127_7360984_0 cellulose binding - - - 1.435e-223 695.0
REGS2_k127_7360984_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 533.0
REGS2_k127_7360984_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 298.0
REGS2_k127_7360984_3 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002891 289.0
REGS2_k127_7360984_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000000000000000107 161.0
REGS2_k127_7360984_6 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 0.0000000000000000000000000000000002351 140.0
REGS2_k127_7360984_7 CoA-transferase family III - - - 0.0000000006372 69.0
REGS2_k127_7402876_0 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 3.193e-201 666.0
REGS2_k127_7402876_1 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 567.0
REGS2_k127_7402876_10 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000364 145.0
REGS2_k127_7402876_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000004868 148.0
REGS2_k127_7402876_12 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000008484 139.0
REGS2_k127_7402876_13 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001192 128.0
REGS2_k127_7402876_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000001096 127.0
REGS2_k127_7402876_15 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000003524 136.0
REGS2_k127_7402876_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000005105 109.0
REGS2_k127_7402876_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000427 105.0
REGS2_k127_7402876_18 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000001659 96.0
REGS2_k127_7402876_19 Histidine kinase K10715 - 2.7.13.3 0.0000000000000008876 86.0
REGS2_k127_7402876_2 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 452.0
REGS2_k127_7402876_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 419.0
REGS2_k127_7402876_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 437.0
REGS2_k127_7402876_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 370.0
REGS2_k127_7402876_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 304.0
REGS2_k127_7402876_7 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000000000000000002929 241.0
REGS2_k127_7402876_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000008804 226.0
REGS2_k127_7402876_9 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000113 154.0
REGS2_k127_7523262_0 4-hydroxyphenylacetate K00483 - 1.14.14.9 1.125e-240 759.0
REGS2_k127_7523262_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 582.0
REGS2_k127_7523262_10 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 314.0
REGS2_k127_7523262_11 Branched-chain-amino-acid aminotransferase-like protein 3 K18482 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 306.0
REGS2_k127_7523262_12 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000103 284.0
REGS2_k127_7523262_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009323 258.0
REGS2_k127_7523262_14 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004256 259.0
REGS2_k127_7523262_15 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000001318 188.0
REGS2_k127_7523262_16 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000007797 174.0
REGS2_k127_7523262_17 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000001308 148.0
REGS2_k127_7523262_18 protein conserved in bacteria - - - 0.0000000000000000000000000002777 129.0
REGS2_k127_7523262_19 - - - - 0.0000000000000000000000000004517 133.0
REGS2_k127_7523262_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 521.0
REGS2_k127_7523262_20 - - - - 0.000000000000000000000000008468 117.0
REGS2_k127_7523262_21 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000002119 91.0
REGS2_k127_7523262_22 TIGRFAM cobaltochelatase, CobN subunit K02230 - 6.6.1.2 0.00000000000002191 84.0
REGS2_k127_7523262_23 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000001795 71.0
REGS2_k127_7523262_24 Putative regulatory protein - - - 0.00000001397 59.0
REGS2_k127_7523262_25 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.0000002746 62.0
REGS2_k127_7523262_26 Major facilitator superfamily K08167 - - 0.0004939 52.0
REGS2_k127_7523262_27 PFAM Major Facilitator Superfamily - - - 0.0008628 51.0
REGS2_k127_7523262_3 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 487.0
REGS2_k127_7523262_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 430.0
REGS2_k127_7523262_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 378.0
REGS2_k127_7523262_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 372.0
REGS2_k127_7523262_7 PFAM oxidoreductase domain protein K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 381.0
REGS2_k127_7523262_8 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 370.0
REGS2_k127_7523262_9 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 373.0
REGS2_k127_777678_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.649e-207 662.0
REGS2_k127_777678_1 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 490.0
REGS2_k127_777678_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 297.0
REGS2_k127_777678_11 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 317.0
REGS2_k127_777678_12 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002074 288.0
REGS2_k127_777678_13 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002661 259.0
REGS2_k127_777678_14 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 243.0
REGS2_k127_777678_15 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004192 234.0
REGS2_k127_777678_16 Cytochrome oxidase assembly protein K02259,K03110 - - 0.0000000000000000000000000000000000000000000000000000000001003 215.0
REGS2_k127_777678_17 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000008129 207.0
REGS2_k127_777678_18 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000001609 200.0
REGS2_k127_777678_19 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000009144 187.0
REGS2_k127_777678_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 400.0
REGS2_k127_777678_20 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000006122 183.0
REGS2_k127_777678_21 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000006217 169.0
REGS2_k127_777678_22 KR domain - - - 0.000000000000000000000000000000000000000006059 163.0
REGS2_k127_777678_23 Haem-degrading - - - 0.00000000000000000000000000000000000000001195 158.0
REGS2_k127_777678_24 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000002339 159.0
REGS2_k127_777678_25 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.00000000000000000000000000000000000000004853 167.0
REGS2_k127_777678_26 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.0000000000000000000000000000000000003447 150.0
REGS2_k127_777678_27 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000569 121.0
REGS2_k127_777678_28 NUDIX domain - - - 0.000000000000000000000000004887 117.0
REGS2_k127_777678_29 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000001716 100.0
REGS2_k127_777678_3 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 353.0
REGS2_k127_777678_30 Protein of unknown function (DUF3106) - - - 0.000000000000000009664 91.0
REGS2_k127_777678_31 - - - - 0.00000000000000002244 85.0
REGS2_k127_777678_32 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000257 79.0
REGS2_k127_777678_33 Tautomerase enzyme - - - 0.0000000001942 68.0
REGS2_k127_777678_34 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000001451 66.0
REGS2_k127_777678_35 Evidence 5 No homology to any previously reported sequences - - - 0.000000004123 67.0
REGS2_k127_777678_36 Putative zinc-finger - - - 0.0001442 51.0
REGS2_k127_777678_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 361.0
REGS2_k127_777678_5 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 349.0
REGS2_k127_777678_6 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 323.0
REGS2_k127_777678_7 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 332.0
REGS2_k127_777678_8 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 311.0
REGS2_k127_777678_9 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 304.0
REGS2_k127_7803485_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 1.173e-226 725.0
REGS2_k127_7803485_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002171 258.0
REGS2_k127_7803485_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001217 231.0
REGS2_k127_7803485_3 Sulfatase K01133 - 3.1.6.6 0.0000000000002741 71.0
REGS2_k127_7803485_4 - - - - 0.0000000003086 66.0
REGS2_k127_7822277_0 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 546.0
REGS2_k127_7822277_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 500.0
REGS2_k127_7822277_10 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 303.0
REGS2_k127_7822277_11 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002671 280.0
REGS2_k127_7822277_12 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003756 286.0
REGS2_k127_7822277_13 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001643 246.0
REGS2_k127_7822277_14 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000286 226.0
REGS2_k127_7822277_15 Dehydrogenase - - - 0.00000000000000000000000000000000000007224 156.0
REGS2_k127_7822277_16 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.00000000000000000000000000000000002661 139.0
REGS2_k127_7822277_17 - - - - 0.00000000000000000000000000000008649 132.0
REGS2_k127_7822277_18 Pfam Chromate transporter K07240 - - 0.00000000000000000000000000001367 131.0
REGS2_k127_7822277_19 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000005645 112.0
REGS2_k127_7822277_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 491.0
REGS2_k127_7822277_20 RNA recognition motif - - - 0.00000000000000000000002146 106.0
REGS2_k127_7822277_21 repeat protein - - - 0.00000000000000000002181 95.0
REGS2_k127_7822277_22 Chromate transporter K07240 - - 0.000000000000000000131 95.0
REGS2_k127_7822277_23 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000001155 91.0
REGS2_k127_7822277_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0000000000000001387 94.0
REGS2_k127_7822277_25 Cupin 2, conserved barrel domain protein - - - 0.000000000000002108 79.0
REGS2_k127_7822277_26 Domain of Unknown function (DUF542) K07322 - - 0.00000000000001603 76.0
REGS2_k127_7822277_27 - - - - 0.00000000000833 76.0
REGS2_k127_7822277_28 GGDEF domain - - - 0.00000000001162 75.0
REGS2_k127_7822277_29 cell redox homeostasis - - - 0.0000000003193 64.0
REGS2_k127_7822277_3 C4-dicarboxylate ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 470.0
REGS2_k127_7822277_30 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000004353 59.0
REGS2_k127_7822277_31 amine dehydrogenase activity K08282,K08884,K14274 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000004844 61.0
REGS2_k127_7822277_32 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.000005947 58.0
REGS2_k127_7822277_33 Thioredoxin-like K02199 - - 0.00001004 57.0
REGS2_k127_7822277_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 442.0
REGS2_k127_7822277_5 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 421.0
REGS2_k127_7822277_6 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 394.0
REGS2_k127_7822277_7 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 389.0
REGS2_k127_7822277_8 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 353.0
REGS2_k127_7822277_9 transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 322.0
REGS2_k127_7950969_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.973e-209 666.0
REGS2_k127_7950969_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 1.521e-195 621.0
REGS2_k127_7950969_10 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 396.0
REGS2_k127_7950969_11 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 391.0
REGS2_k127_7950969_12 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 398.0
REGS2_k127_7950969_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 376.0
REGS2_k127_7950969_14 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 374.0
REGS2_k127_7950969_15 dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 374.0
REGS2_k127_7950969_16 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 320.0
REGS2_k127_7950969_17 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 - 2.5.1.31,2.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 307.0
REGS2_k127_7950969_18 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 314.0
REGS2_k127_7950969_19 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 302.0
REGS2_k127_7950969_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 617.0
REGS2_k127_7950969_20 GTPase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 297.0
REGS2_k127_7950969_21 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005311 249.0
REGS2_k127_7950969_22 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001048 246.0
REGS2_k127_7950969_23 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000002235 241.0
REGS2_k127_7950969_24 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000004233 249.0
REGS2_k127_7950969_25 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001944 235.0
REGS2_k127_7950969_26 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000001136 240.0
REGS2_k127_7950969_27 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000001864 233.0
REGS2_k127_7950969_28 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000001455 225.0
REGS2_k127_7950969_29 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000001069 230.0
REGS2_k127_7950969_3 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 569.0
REGS2_k127_7950969_30 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000312 230.0
REGS2_k127_7950969_31 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000006014 220.0
REGS2_k127_7950969_32 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000003313 221.0
REGS2_k127_7950969_33 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000003553 213.0
REGS2_k127_7950969_34 Responsible for synthesis of pseudouridine from uracil K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000001254 202.0
REGS2_k127_7950969_35 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000001843 209.0
REGS2_k127_7950969_36 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000001173 199.0
REGS2_k127_7950969_37 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000003071 187.0
REGS2_k127_7950969_38 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000002144 175.0
REGS2_k127_7950969_39 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000000000003859 176.0
REGS2_k127_7950969_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 564.0
REGS2_k127_7950969_40 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000001084 183.0
REGS2_k127_7950969_41 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000001382 175.0
REGS2_k127_7950969_42 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000005634 181.0
REGS2_k127_7950969_43 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000005443 169.0
REGS2_k127_7950969_44 PIN domain - - - 0.000000000000000000000000000000000000000001983 159.0
REGS2_k127_7950969_45 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000827 153.0
REGS2_k127_7950969_46 dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000008323 145.0
REGS2_k127_7950969_47 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000005694 145.0
REGS2_k127_7950969_48 NUDIX domain - - - 0.0000000000000000000000000000000003143 147.0
REGS2_k127_7950969_49 4-Oxalocrotonate decarboxylase K01617 - 4.1.1.77 0.0000000000000000000000000000000006327 149.0
REGS2_k127_7950969_5 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 513.0
REGS2_k127_7950969_50 EamA-like transporter family - - - 0.0000000000000000000000000000001292 135.0
REGS2_k127_7950969_51 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000000006179 111.0
REGS2_k127_7950969_52 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.00000000000000000000000006103 115.0
REGS2_k127_7950969_53 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000008829 110.0
REGS2_k127_7950969_54 - - - - 0.000000000000000000000001951 116.0
REGS2_k127_7950969_55 O-linked GlcNAc transferase - - - 0.0000000000000000000000288 115.0
REGS2_k127_7950969_56 PFAM Abortive infection protein K07052 - - 0.0000000000000000000002225 110.0
REGS2_k127_7950969_57 translation initiation factor activity - - - 0.0000000000000000004591 89.0
REGS2_k127_7950969_58 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000002919 95.0
REGS2_k127_7950969_59 Protein of unknown function (DUF1232) - - - 0.0000000000000009869 84.0
REGS2_k127_7950969_6 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 499.0
REGS2_k127_7950969_60 Cytochrome C' - - - 0.0000000000002513 81.0
REGS2_k127_7950969_61 InterPro IPR007367 - - - 0.000000947 59.0
REGS2_k127_7950969_62 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.0000466 52.0
REGS2_k127_7950969_63 Peptidase family C25 - - - 0.0003978 48.0
REGS2_k127_7950969_64 YceI-like domain - - - 0.0008495 51.0
REGS2_k127_7950969_7 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 482.0
REGS2_k127_7950969_8 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 486.0
REGS2_k127_7950969_9 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 401.0
REGS2_k127_7981928_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1392.0
REGS2_k127_7981928_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 389.0
REGS2_k127_7981928_10 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000001466 225.0
REGS2_k127_7981928_11 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000004667 206.0
REGS2_k127_7981928_12 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000003037 205.0
REGS2_k127_7981928_13 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000007899 186.0
REGS2_k127_7981928_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000006732 168.0
REGS2_k127_7981928_15 Belongs to the ompA family K03640 - - 0.000000000000000000000000000001255 134.0
REGS2_k127_7981928_16 Belongs to the UPF0296 family K09777 - - 0.0000000000000000000003416 99.0
REGS2_k127_7981928_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.0000000000000004893 91.0
REGS2_k127_7981928_18 - - - - 0.000000000000000805 80.0
REGS2_k127_7981928_19 NHL repeat - - - 0.0000000000001661 85.0
REGS2_k127_7981928_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 323.0
REGS2_k127_7981928_20 Belongs to the ompA family K20276 - - 0.0000000000001661 85.0
REGS2_k127_7981928_21 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000001773 76.0
REGS2_k127_7981928_22 Transposase K07483 - - 0.000002471 56.0
REGS2_k127_7981928_23 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000002702 50.0
REGS2_k127_7981928_24 - - - - 0.000005486 55.0
REGS2_k127_7981928_25 Putative transposase - - - 0.0001022 51.0
REGS2_k127_7981928_26 ATPases associated with a variety of cellular activities K02049 - - 0.0001126 50.0
REGS2_k127_7981928_27 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0001553 53.0
REGS2_k127_7981928_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002525 254.0
REGS2_k127_7981928_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000006362 235.0
REGS2_k127_7981928_5 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001135 229.0
REGS2_k127_7981928_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000894 222.0
REGS2_k127_7981928_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000004074 241.0
REGS2_k127_7981928_8 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000009171 217.0
REGS2_k127_7981928_9 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000005251 224.0
REGS2_k127_8037908_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.476e-280 877.0
REGS2_k127_8037908_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 472.0
REGS2_k127_8037908_2 Belongs to the mandelate racemase muconate lactonizing enzyme family K01856 - 5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 312.0
REGS2_k127_8037908_3 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 254.0
REGS2_k127_8037908_4 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001321 260.0
REGS2_k127_8037908_5 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000003289 160.0
REGS2_k127_8037908_6 PFAM Methyltransferase type - - - 0.00000000000001583 84.0
REGS2_k127_8037908_7 Fructose-bisphosphate aldolase class-I - - - 0.0000002051 59.0
REGS2_k127_8064591_0 Belongs to the ClpA ClpB family K03695,K03696 - - 5.371e-318 993.0
REGS2_k127_8064591_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 589.0
REGS2_k127_8064591_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002671 284.0
REGS2_k127_8064591_11 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000008849 276.0
REGS2_k127_8064591_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003398 246.0
REGS2_k127_8064591_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000004213 243.0
REGS2_k127_8064591_14 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000009128 242.0
REGS2_k127_8064591_15 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000004922 230.0
REGS2_k127_8064591_16 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000002957 214.0
REGS2_k127_8064591_17 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000008853 202.0
REGS2_k127_8064591_18 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.00000000000000000000000000000000000000000000008044 187.0
REGS2_k127_8064591_19 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000001486 175.0
REGS2_k127_8064591_2 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 480.0
REGS2_k127_8064591_20 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000001965 168.0
REGS2_k127_8064591_21 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.000000000000000000000000000000000000006653 166.0
REGS2_k127_8064591_22 Psort location Cytoplasmic, score 8.96 K09949 - - 0.0000000000000000000000000000003065 141.0
REGS2_k127_8064591_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000004749 139.0
REGS2_k127_8064591_24 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000655 124.0
REGS2_k127_8064591_25 Glycosyl transferase 4-like domain - - - 0.0000000000000000002026 103.0
REGS2_k127_8064591_26 PFAM Outer membrane K06142 - - 0.0000000000001462 78.0
REGS2_k127_8064591_27 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000002736 74.0
REGS2_k127_8064591_3 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 423.0
REGS2_k127_8064591_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 346.0
REGS2_k127_8064591_5 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 366.0
REGS2_k127_8064591_6 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 340.0
REGS2_k127_8064591_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 312.0
REGS2_k127_8064591_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 305.0
REGS2_k127_8064591_9 inositol 2-dehydrogenase activity K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 300.0
REGS2_k127_8122937_0 PFAM Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 577.0
REGS2_k127_8122937_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 422.0
REGS2_k127_8122937_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 295.0
REGS2_k127_8122937_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000003613 261.0
REGS2_k127_8122937_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000124 190.0
REGS2_k127_8122937_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000005938 144.0
REGS2_k127_8122937_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000001036 102.0
REGS2_k127_8271420_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.238e-258 829.0
REGS2_k127_8271420_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 6.335e-254 792.0
REGS2_k127_8271420_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 451.0
REGS2_k127_8271420_11 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 437.0
REGS2_k127_8271420_12 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 437.0
REGS2_k127_8271420_13 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 437.0
REGS2_k127_8271420_14 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 415.0
REGS2_k127_8271420_15 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 400.0
REGS2_k127_8271420_16 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 378.0
REGS2_k127_8271420_17 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 370.0
REGS2_k127_8271420_18 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 354.0
REGS2_k127_8271420_19 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 341.0
REGS2_k127_8271420_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 3.069e-235 754.0
REGS2_k127_8271420_20 Hydrogenase expression formation protein (HypE) K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 333.0
REGS2_k127_8271420_21 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 314.0
REGS2_k127_8271420_22 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 313.0
REGS2_k127_8271420_23 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005821 312.0
REGS2_k127_8271420_24 Exonuclease K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009029 272.0
REGS2_k127_8271420_25 PFAM Formiminotransferase domain, N-terminal subdomain K00603,K01746 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001768 266.0
REGS2_k127_8271420_26 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000005601 220.0
REGS2_k127_8271420_27 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000001283 173.0
REGS2_k127_8271420_28 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000002612 162.0
REGS2_k127_8271420_29 endonuclease III K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.00000000000000000000000000000000000000001104 165.0
REGS2_k127_8271420_3 amino acid - - - 6.45e-205 654.0
REGS2_k127_8271420_30 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000004379 153.0
REGS2_k127_8271420_31 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000007531 150.0
REGS2_k127_8271420_32 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000001447 143.0
REGS2_k127_8271420_33 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000187 146.0
REGS2_k127_8271420_34 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002474 143.0
REGS2_k127_8271420_35 PFAM HNH endonuclease K07451 - - 0.0000000000000000000000000000000000283 138.0
REGS2_k127_8271420_36 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000001072 124.0
REGS2_k127_8271420_37 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000001309 120.0
REGS2_k127_8271420_38 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000003406 113.0
REGS2_k127_8271420_39 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001038 108.0
REGS2_k127_8271420_4 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 601.0
REGS2_k127_8271420_40 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000004817 99.0
REGS2_k127_8271420_41 Metal-sensitive transcriptional repressor - - - 0.000000000000000000002303 96.0
REGS2_k127_8271420_43 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000007703 81.0
REGS2_k127_8271420_44 monooxygenase activity K00688 - 2.4.1.1 0.0000000000005584 70.0
REGS2_k127_8271420_45 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000009992 77.0
REGS2_k127_8271420_46 probably involved in intracellular septation - - - 0.0000000001487 70.0
REGS2_k127_8271420_47 VanZ like family - - - 0.0000000003052 68.0
REGS2_k127_8271420_48 TIGRFAM competence protein ComEA helix-hairpin-helix repeat region K02237 - - 0.0000000005318 65.0
REGS2_k127_8271420_49 Protein of unknown function (DUF721) - - - 0.000000002333 64.0
REGS2_k127_8271420_5 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 557.0
REGS2_k127_8271420_50 Belongs to the 'phage' integrase family K03733,K04763 - - 0.000000009908 63.0
REGS2_k127_8271420_51 Protein of unknown function (DUF971) K03593 - - 0.00000001101 64.0
REGS2_k127_8271420_52 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000003382 61.0
REGS2_k127_8271420_53 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000004552 54.0
REGS2_k127_8271420_54 Protein of unknown function (DUF2889) - - - 0.0003055 52.0
REGS2_k127_8271420_6 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 492.0
REGS2_k127_8271420_7 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 490.0
REGS2_k127_8271420_8 Replicative DNA helicase K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 479.0
REGS2_k127_8271420_9 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 481.0
REGS2_k127_8280379_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 432.0
REGS2_k127_8280379_1 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 410.0
REGS2_k127_8280379_10 Catalyzes a key regulatory step in fatty acid biosynthesis K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000002225 243.0
REGS2_k127_8280379_11 Conserved protein of dim6 ntab family - - - 0.00000000000000000000000000000000000000000000000000000000000154 216.0
REGS2_k127_8280379_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000164 224.0
REGS2_k127_8280379_13 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000002259 213.0
REGS2_k127_8280379_14 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000426 194.0
REGS2_k127_8280379_15 Beta-galactosidase - - - 0.00000000000000000000000000000000000005705 156.0
REGS2_k127_8280379_16 Transcription termination factor nusG - - - 0.000000000000000000000000000000000008467 143.0
REGS2_k127_8280379_17 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000001572 121.0
REGS2_k127_8280379_18 InterPro IPR007367 - - - 0.000000000000000000001073 100.0
REGS2_k127_8280379_19 Receptor family ligand binding region K01999 - - 0.000000000000000000004677 106.0
REGS2_k127_8280379_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 361.0
REGS2_k127_8280379_20 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000306 96.0
REGS2_k127_8280379_21 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000004032 79.0
REGS2_k127_8280379_22 - - - - 0.00000000004207 72.0
REGS2_k127_8280379_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000001401 64.0
REGS2_k127_8280379_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 360.0
REGS2_k127_8280379_4 Dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
REGS2_k127_8280379_5 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002214 276.0
REGS2_k127_8280379_6 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003321 250.0
REGS2_k127_8280379_7 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K01784,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000001088 254.0
REGS2_k127_8280379_8 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001846 244.0
REGS2_k127_8280379_9 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002375 247.0
REGS2_k127_8289396_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 5.957e-201 666.0
REGS2_k127_8289396_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 333.0
REGS2_k127_8289396_2 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 315.0
REGS2_k127_8289396_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
REGS2_k127_8289396_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000004221 183.0
REGS2_k127_8289396_5 DinB family - - - 0.00000000000000000000000000000000002183 146.0
REGS2_k127_8289396_6 membrane transporter protein K07090 - - 0.00000000000000000000000000557 119.0
REGS2_k127_8289396_7 SnoaL-like domain - - - 0.0009726 42.0
REGS2_k127_837089_0 Hydantoinase B/oxoprolinase - - - 2.691e-261 821.0
REGS2_k127_837089_1 Hydantoinase/oxoprolinase - - - 8.114e-248 782.0
REGS2_k127_837089_2 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 506.0
REGS2_k127_837089_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 425.0
REGS2_k127_837089_4 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 352.0
REGS2_k127_837089_5 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004225 260.0
REGS2_k127_837089_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002985 259.0
REGS2_k127_837089_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000227 260.0
REGS2_k127_837089_8 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000006608 233.0
REGS2_k127_837089_9 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000001312 239.0
REGS2_k127_8428737_0 ABC transporter K03701 - - 0.0 1256.0
REGS2_k127_8428737_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 498.0
REGS2_k127_8428737_2 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 426.0
REGS2_k127_8428737_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 436.0
REGS2_k127_8428737_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001141 268.0
REGS2_k127_8428737_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.0000000000000000000000000000000000000000000000000000000000007511 231.0
REGS2_k127_8428737_6 Thioredoxin domain - - - 0.0000000000000000000000000000000000001106 146.0
REGS2_k127_8428737_7 DinB superfamily - - - 0.00000000000000000000000000000000306 137.0
REGS2_k127_8428737_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000001334 139.0
REGS2_k127_8428737_9 Thioredoxin domain - - - 0.00000000000000000002029 92.0
REGS2_k127_909276_0 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 511.0
REGS2_k127_909276_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 400.0
REGS2_k127_909276_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000385 225.0
REGS2_k127_909276_3 Smr domain - - - 0.0000000000000000000000000001378 117.0
REGS2_k127_909276_4 PFAM MaoC like domain - - - 0.000000000000000000000007403 116.0
REGS2_k127_909276_5 Putative ATP-binding cassette K01992 - - 0.0000000000001675 83.0
REGS2_k127_909276_6 - - - - 0.0006429 45.0
REGS2_k127_919083_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 514.0
REGS2_k127_919083_1 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 489.0
REGS2_k127_919083_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 486.0
REGS2_k127_919083_3 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 422.0
REGS2_k127_919083_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 394.0
REGS2_k127_919083_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 331.0
REGS2_k127_919083_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
REGS2_k127_919083_7 Binding-protein-dependent transport system inner membrane component K02034,K13891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001667 272.0
REGS2_k127_919083_8 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001719 257.0