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Overview

ID MAG03334
Name REGS2_bin.23
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus
Species
Assembly information
Completeness (%) 82.01
Contamination (%) 1.01
GC content (%) 69.0
N50 (bp) 25,084
Genome size (bp) 2,955,694

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2532

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1007401_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1171.0
REGS2_k127_1007401_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 351.0
REGS2_k127_1007401_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 332.0
REGS2_k127_1007401_3 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004779 257.0
REGS2_k127_1007401_4 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000005382 199.0
REGS2_k127_1007401_5 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000001455 163.0
REGS2_k127_1007401_6 PFAM blue (type 1) copper domain protein - - - 0.0000000000002036 81.0
REGS2_k127_1007401_7 Histone deacetylase domain - - - 0.00000000001281 66.0
REGS2_k127_1007401_8 chlorophyll binding - - - 0.00000006047 66.0
REGS2_k127_1076749_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 610.0
REGS2_k127_1076749_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 577.0
REGS2_k127_1076749_10 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275,K02826,K15864 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12,1.7.2.1,1.7.99.1,1.9.3.1 0.000000000000000218 88.0
REGS2_k127_1076749_11 Cytochrome c K17223 - - 0.0000000000001419 84.0
REGS2_k127_1076749_12 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.0000000001855 73.0
REGS2_k127_1076749_2 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 389.0
REGS2_k127_1076749_3 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 388.0
REGS2_k127_1076749_4 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004657 290.0
REGS2_k127_1076749_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003287 271.0
REGS2_k127_1076749_6 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000003003 175.0
REGS2_k127_1076749_7 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000009307 115.0
REGS2_k127_1076749_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000007839 119.0
REGS2_k127_1076749_9 CHRD domain - - - 0.000000000000000005296 97.0
REGS2_k127_1093973_0 cellulose binding - - - 0.0 1258.0
REGS2_k127_1093973_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.71e-262 836.0
REGS2_k127_1093973_10 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000587 191.0
REGS2_k127_1093973_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000007252 97.0
REGS2_k127_1093973_12 sequence-specific DNA binding K07729 - - 0.000000000000000002269 89.0
REGS2_k127_1093973_13 periplasmic or secreted lipoprotein - - - 0.00000000000000001263 91.0
REGS2_k127_1093973_14 Putative regulatory protein - - - 0.0000000000000003361 81.0
REGS2_k127_1093973_15 Sporulation and spore germination - - - 0.0000000000005097 83.0
REGS2_k127_1093973_16 Universal stress protein family - - - 0.000003416 57.0
REGS2_k127_1093973_2 Bacterial protein of unknown function (DUF885) - - - 6.508e-206 657.0
REGS2_k127_1093973_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 546.0
REGS2_k127_1093973_4 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 508.0
REGS2_k127_1093973_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 401.0
REGS2_k127_1093973_6 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 371.0
REGS2_k127_1093973_7 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 365.0
REGS2_k127_1093973_8 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 291.0
REGS2_k127_1093973_9 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000002136 221.0
REGS2_k127_1102892_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 593.0
REGS2_k127_1102892_1 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 396.0
REGS2_k127_1102892_10 CHASE - - - 0.00000000000000000000000000000000000000000000000000000000000006318 228.0
REGS2_k127_1102892_11 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000001009 213.0
REGS2_k127_1102892_12 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000003622 168.0
REGS2_k127_1102892_13 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000001307 153.0
REGS2_k127_1102892_14 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000004884 132.0
REGS2_k127_1102892_15 phosphorelay signal transduction system - - - 0.000000000000000000000000003574 129.0
REGS2_k127_1102892_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000001852 115.0
REGS2_k127_1102892_17 - - - - 0.0000000000000000000001633 111.0
REGS2_k127_1102892_18 luxR family - - - 0.00000000000000000004352 98.0
REGS2_k127_1102892_19 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000002628 97.0
REGS2_k127_1102892_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 367.0
REGS2_k127_1102892_20 - - - - 0.000000000000000529 91.0
REGS2_k127_1102892_21 PFAM regulatory protein, MerR - - - 0.0000000000000006564 83.0
REGS2_k127_1102892_22 AhpC Tsa family - - - 0.000000653 53.0
REGS2_k127_1102892_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 337.0
REGS2_k127_1102892_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 333.0
REGS2_k127_1102892_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 292.0
REGS2_k127_1102892_6 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007413 291.0
REGS2_k127_1102892_7 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000006141 265.0
REGS2_k127_1102892_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000244 255.0
REGS2_k127_1102892_9 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000001003 236.0
REGS2_k127_1117205_0 Conserved region in glutamate synthase - - - 0.0 1258.0
REGS2_k127_1117205_1 ACT domain K12524 - 1.1.1.3,2.7.2.4 6.573e-260 832.0
REGS2_k127_1117205_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 511.0
REGS2_k127_1117205_3 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 468.0
REGS2_k127_1117205_4 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 355.0
REGS2_k127_1117205_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001002 288.0
REGS2_k127_1117205_6 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000002452 248.0
REGS2_k127_1117205_7 GHMP kinases C terminal K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000001904 216.0
REGS2_k127_1117205_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000001327 161.0
REGS2_k127_1136180_0 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 499.0
REGS2_k127_1136180_1 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 391.0
REGS2_k127_1136180_10 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001445 289.0
REGS2_k127_1136180_11 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005939 286.0
REGS2_k127_1136180_12 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000003318 243.0
REGS2_k127_1136180_13 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000003747 231.0
REGS2_k127_1136180_14 - - - - 0.0000000000000000000000000000000000000000000000000001168 203.0
REGS2_k127_1136180_15 PFAM Peptidase family M20 M25 M40 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000107 166.0
REGS2_k127_1136180_16 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000018 157.0
REGS2_k127_1136180_17 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000001455 148.0
REGS2_k127_1136180_18 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000001028 126.0
REGS2_k127_1136180_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 351.0
REGS2_k127_1136180_3 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 364.0
REGS2_k127_1136180_4 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 338.0
REGS2_k127_1136180_5 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 345.0
REGS2_k127_1136180_6 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 323.0
REGS2_k127_1136180_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 302.0
REGS2_k127_1136180_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 287.0
REGS2_k127_1136180_9 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001992 291.0
REGS2_k127_1161366_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 440.0
REGS2_k127_1161366_1 peptidase M24 K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 386.0
REGS2_k127_1161366_10 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000009832 154.0
REGS2_k127_1161366_12 cheY-homologous receiver domain K02485 - - 0.000000000000000000003369 108.0
REGS2_k127_1161366_13 fatty acid desaturase - - - 0.00000000000000007325 92.0
REGS2_k127_1161366_14 - - - - 0.000001078 59.0
REGS2_k127_1161366_15 secretion protein HlyD K01993 - - 0.0000421 55.0
REGS2_k127_1161366_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 299.0
REGS2_k127_1161366_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 302.0
REGS2_k127_1161366_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001326 271.0
REGS2_k127_1161366_5 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001146 252.0
REGS2_k127_1161366_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000003482 215.0
REGS2_k127_1161366_7 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000008007 201.0
REGS2_k127_1161366_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000009948 184.0
REGS2_k127_1161366_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000001427 184.0
REGS2_k127_119412_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 611.0
REGS2_k127_119412_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 565.0
REGS2_k127_119412_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 353.0
REGS2_k127_119412_11 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 346.0
REGS2_k127_119412_12 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 334.0
REGS2_k127_119412_13 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 329.0
REGS2_k127_119412_14 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 313.0
REGS2_k127_119412_15 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006566 286.0
REGS2_k127_119412_16 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
REGS2_k127_119412_17 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005671 286.0
REGS2_k127_119412_18 Pfam:Arch_ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001034 284.0
REGS2_k127_119412_19 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000001956 224.0
REGS2_k127_119412_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 529.0
REGS2_k127_119412_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
REGS2_k127_119412_21 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000000000000000000000000007294 168.0
REGS2_k127_119412_22 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.0000000000000000000000000000000000009955 158.0
REGS2_k127_119412_23 Domain of Unknown Function (DUF1206) - - - 0.000000000000000000000000000000003224 138.0
REGS2_k127_119412_24 Virulence factor BrkB K07058 - - 0.0000000000000000000009037 108.0
REGS2_k127_119412_25 - - - - 0.000000000000000004454 94.0
REGS2_k127_119412_26 Glutaredoxin K03676,K18917 - 1.20.4.3 0.00000000001455 72.0
REGS2_k127_119412_27 PFAM blue (type 1) copper domain protein - - - 0.0000000001357 70.0
REGS2_k127_119412_3 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 511.0
REGS2_k127_119412_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 470.0
REGS2_k127_119412_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 458.0
REGS2_k127_119412_6 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 433.0
REGS2_k127_119412_7 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 434.0
REGS2_k127_119412_8 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 400.0
REGS2_k127_119412_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 357.0
REGS2_k127_1365416_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.705e-249 830.0
REGS2_k127_1365416_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 526.0
REGS2_k127_1365416_10 histone H2A K63-linked ubiquitination K10914 - - 0.00000000000000000000000000000000003142 153.0
REGS2_k127_1365416_11 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000004862 138.0
REGS2_k127_1365416_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000421 105.0
REGS2_k127_1365416_13 DnaJ molecular chaperone homology domain - - - 0.000000000000000002915 100.0
REGS2_k127_1365416_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000006793 83.0
REGS2_k127_1365416_16 Domain of unknown function (DUF4126) - - - 0.0000000004893 73.0
REGS2_k127_1365416_17 Protein of unknown function (DUF3761) - - - 0.000000002 69.0
REGS2_k127_1365416_18 Predicted membrane protein (DUF2232) - - - 0.00004516 56.0
REGS2_k127_1365416_19 RNA-binding protein containing a PIN domain K06962 - - 0.0002511 49.0
REGS2_k127_1365416_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 491.0
REGS2_k127_1365416_20 Domain of unknown function (DUF4388) - - - 0.0005058 53.0
REGS2_k127_1365416_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 470.0
REGS2_k127_1365416_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 409.0
REGS2_k127_1365416_5 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000001523 207.0
REGS2_k127_1365416_6 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000001969 190.0
REGS2_k127_1365416_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000004869 175.0
REGS2_k127_1365416_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000004877 169.0
REGS2_k127_1365416_9 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000000001258 168.0
REGS2_k127_138110_0 lipopolysaccharide transport K22110 - - 0.0 1399.0
REGS2_k127_138110_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 7.519e-208 668.0
REGS2_k127_138110_10 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.00000000000000000000000000006522 137.0
REGS2_k127_138110_11 Universal stress protein family - - - 0.000000000000000000000000001098 119.0
REGS2_k127_138110_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000008223 126.0
REGS2_k127_138110_13 cheY-homologous receiver domain - - - 0.0000000000000000000000009975 109.0
REGS2_k127_138110_14 helix_turn_helix, Lux Regulon - - - 0.0000000000000000005783 98.0
REGS2_k127_138110_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000001354 91.0
REGS2_k127_138110_16 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000009196 78.0
REGS2_k127_138110_17 FeoA K04758 - - 0.000003649 57.0
REGS2_k127_138110_18 DNA-sulfur modification-associated - - - 0.000003853 59.0
REGS2_k127_138110_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 374.0
REGS2_k127_138110_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 367.0
REGS2_k127_138110_4 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000138 284.0
REGS2_k127_138110_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000004556 226.0
REGS2_k127_138110_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000004431 208.0
REGS2_k127_138110_7 PFAM peptidase K16922 - - 0.00000000000000000000000000000000000000000000000000000389 217.0
REGS2_k127_138110_8 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000001391 199.0
REGS2_k127_138110_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000001378 183.0
REGS2_k127_1466159_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001056 231.0
REGS2_k127_1466159_1 Damage-inducible protein DinB - - - 0.000000000000000000000000000000000000000000000000001336 187.0
REGS2_k127_1466159_2 - - - - 0.0000000000000000000000000000000000002103 158.0
REGS2_k127_1466159_3 - - - - 0.000000000000000000000000000007026 138.0
REGS2_k127_1489574_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.515e-278 870.0
REGS2_k127_1489574_1 Elongation factor G, domain IV K02355 - - 8.044e-208 666.0
REGS2_k127_1489574_10 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000002789 208.0
REGS2_k127_1489574_11 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000001438 126.0
REGS2_k127_1489574_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 574.0
REGS2_k127_1489574_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 569.0
REGS2_k127_1489574_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 466.0
REGS2_k127_1489574_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 388.0
REGS2_k127_1489574_6 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 396.0
REGS2_k127_1489574_7 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 365.0
REGS2_k127_1489574_8 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009936 280.0
REGS2_k127_1489574_9 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000006127 206.0
REGS2_k127_14964_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 292.0
REGS2_k127_14964_1 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000002524 225.0
REGS2_k127_14964_2 Redoxin domain protein - - - 0.00000000004807 76.0
REGS2_k127_1560677_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 419.0
REGS2_k127_1560677_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 411.0
REGS2_k127_1560677_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 354.0
REGS2_k127_1560677_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 311.0
REGS2_k127_1560677_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 290.0
REGS2_k127_1560677_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 273.0
REGS2_k127_1560677_6 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000008828 248.0
REGS2_k127_1560677_7 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000001055 166.0
REGS2_k127_1560677_8 UPF0761 membrane protein K07058 - - 0.0000000000000000001798 102.0
REGS2_k127_1560677_9 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000003982 92.0
REGS2_k127_1574821_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.391e-219 694.0
REGS2_k127_1574821_1 PFAM peptidase M61 - - - 1.211e-196 632.0
REGS2_k127_1574821_10 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 391.0
REGS2_k127_1574821_11 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 358.0
REGS2_k127_1574821_12 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 347.0
REGS2_k127_1574821_13 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 351.0
REGS2_k127_1574821_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 338.0
REGS2_k127_1574821_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 332.0
REGS2_k127_1574821_16 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
REGS2_k127_1574821_17 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 324.0
REGS2_k127_1574821_18 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 319.0
REGS2_k127_1574821_19 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 297.0
REGS2_k127_1574821_2 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 627.0
REGS2_k127_1574821_20 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 317.0
REGS2_k127_1574821_21 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009952 269.0
REGS2_k127_1574821_22 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000005101 244.0
REGS2_k127_1574821_23 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000001262 254.0
REGS2_k127_1574821_24 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000006942 239.0
REGS2_k127_1574821_25 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000001562 191.0
REGS2_k127_1574821_26 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000004034 171.0
REGS2_k127_1574821_27 DinB family - - - 0.0000000000000000000000000000000000000000001728 165.0
REGS2_k127_1574821_28 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000001787 169.0
REGS2_k127_1574821_29 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000001173 162.0
REGS2_k127_1574821_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 535.0
REGS2_k127_1574821_30 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000002262 167.0
REGS2_k127_1574821_31 MoaC family K03637 - 4.6.1.17 0.00000000000000000000000000000000000001246 158.0
REGS2_k127_1574821_32 Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000005543 161.0
REGS2_k127_1574821_33 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000497 158.0
REGS2_k127_1574821_34 Molybdenum cofactor biosynthesis protein B - - - 0.00000000000000000000000000000000001409 145.0
REGS2_k127_1574821_35 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000001805 149.0
REGS2_k127_1574821_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000001473 119.0
REGS2_k127_1574821_37 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000009696 124.0
REGS2_k127_1574821_38 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000001582 115.0
REGS2_k127_1574821_39 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000003594 108.0
REGS2_k127_1574821_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 541.0
REGS2_k127_1574821_40 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000001056 102.0
REGS2_k127_1574821_41 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000008626 108.0
REGS2_k127_1574821_42 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000001153 100.0
REGS2_k127_1574821_43 Glycoside hydrolase 15-related - - - 0.0000000000000000001285 98.0
REGS2_k127_1574821_44 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000001624 93.0
REGS2_k127_1574821_45 Protein of unknown function (DUF1326) - - - 0.0000000000000000002569 98.0
REGS2_k127_1574821_46 molybdenum cofactor guanylyltransferase activity K02379,K03752 - 2.7.7.77 0.00000000000000003751 89.0
REGS2_k127_1574821_47 Glycosyl transferase, family 2 K00786 - - 0.00000000000000005933 92.0
REGS2_k127_1574821_49 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000871 75.0
REGS2_k127_1574821_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 499.0
REGS2_k127_1574821_50 Yip1 domain - - - 0.00000000002355 78.0
REGS2_k127_1574821_51 - - - - 0.000000000181 70.0
REGS2_k127_1574821_52 - - - - 0.0000001374 63.0
REGS2_k127_1574821_53 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000001568 54.0
REGS2_k127_1574821_54 - - - - 0.000004593 55.0
REGS2_k127_1574821_55 hyperosmotic response K04065 - - 0.00006585 52.0
REGS2_k127_1574821_56 dehydratase K02372 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.0001641 52.0
REGS2_k127_1574821_6 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 473.0
REGS2_k127_1574821_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 470.0
REGS2_k127_1574821_8 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 409.0
REGS2_k127_1574821_9 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 387.0
REGS2_k127_1646397_0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 506.0
REGS2_k127_1646397_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 486.0
REGS2_k127_1646397_10 - - - - 0.000000000000000000000000000000000000008126 151.0
REGS2_k127_1646397_11 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000003416 144.0
REGS2_k127_1646397_12 - - - - 0.0000000000000000000000000000127 127.0
REGS2_k127_1646397_13 PFAM regulatory protein, MarR - - - 0.00000000000000000000000001533 117.0
REGS2_k127_1646397_14 Domain of unknown function (DU1801) - - - 0.0000000000000000000005397 98.0
REGS2_k127_1646397_15 - - - - 0.000000000000000000002541 97.0
REGS2_k127_1646397_16 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000003109 89.0
REGS2_k127_1646397_18 Domain of unknown function (DUF4388) - - - 0.0000000004196 72.0
REGS2_k127_1646397_19 NmrA-like family - - - 0.00000001267 61.0
REGS2_k127_1646397_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 410.0
REGS2_k127_1646397_20 Tetratricopeptide repeat - - - 0.00000003218 64.0
REGS2_k127_1646397_21 - - - - 0.0000001182 59.0
REGS2_k127_1646397_22 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000003203 51.0
REGS2_k127_1646397_23 - - - - 0.000001866 52.0
REGS2_k127_1646397_25 nuclease activity K06218 - - 0.000006732 54.0
REGS2_k127_1646397_26 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00002873 56.0
REGS2_k127_1646397_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 307.0
REGS2_k127_1646397_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005535 278.0
REGS2_k127_1646397_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005047 271.0
REGS2_k127_1646397_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
REGS2_k127_1646397_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004779 210.0
REGS2_k127_1646397_8 - - - - 0.0000000000000000000000000000000000000000001262 166.0
REGS2_k127_1646397_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000001068 171.0
REGS2_k127_1730523_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 591.0
REGS2_k127_1730523_1 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000001753 164.0
REGS2_k127_1730523_2 Tetratricopeptide repeat - - - 0.00000000000000000000000005275 115.0
REGS2_k127_1730523_3 YXWGXW repeat (2 copies) - - - 0.00000000000000000000772 98.0
REGS2_k127_1730523_4 COG0457 FOG TPR repeat - - - 0.0000000000000000005891 92.0
REGS2_k127_1730523_5 YXWGXW repeat (2 copies) - - - 0.0000000006125 60.0
REGS2_k127_1765120_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 318.0
REGS2_k127_1765120_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004434 286.0
REGS2_k127_1765120_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000005517 223.0
REGS2_k127_1765120_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000787 195.0
REGS2_k127_1765120_4 - K01992,K19341 - - 0.0000000000000000000000000000008158 139.0
REGS2_k127_1765120_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.00000000001201 69.0
REGS2_k127_1765120_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000002609 68.0
REGS2_k127_1793129_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 5.896e-319 1026.0
REGS2_k127_1793129_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 486.0
REGS2_k127_1793129_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 468.0
REGS2_k127_1793129_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 385.0
REGS2_k127_1793129_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 386.0
REGS2_k127_1793129_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 290.0
REGS2_k127_1793129_6 COGs COG3603 conserved K09707 - - 0.000000000000000000000000000000003187 142.0
REGS2_k127_1793129_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000002621 113.0
REGS2_k127_1793129_8 Protein of unknown function (DUF3179) - - - 0.00000000000000000009236 104.0
REGS2_k127_1811044_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.167e-229 720.0
REGS2_k127_1811044_1 Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 474.0
REGS2_k127_1811044_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000882 284.0
REGS2_k127_1811044_3 23S rRNA-intervening sequence protein - - - 0.00000000000000000007661 102.0
REGS2_k127_1811044_4 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000001751 93.0
REGS2_k127_1811044_5 CoA carboxylase activity K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.0000000000007598 81.0
REGS2_k127_1811044_6 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000003774 66.0
REGS2_k127_1811044_7 Protein of unknown function (DUF507) K09804 - - 0.0005807 50.0
REGS2_k127_1841674_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 630.0
REGS2_k127_1841674_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 548.0
REGS2_k127_1841674_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004334 277.0
REGS2_k127_1841674_11 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004419 260.0
REGS2_k127_1841674_12 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004843 258.0
REGS2_k127_1841674_13 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000589 269.0
REGS2_k127_1841674_14 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000001448 231.0
REGS2_k127_1841674_15 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000006115 192.0
REGS2_k127_1841674_16 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000006612 175.0
REGS2_k127_1841674_17 Subtilase family - - - 0.0000000000000000000000000000000000000000009239 181.0
REGS2_k127_1841674_18 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000002244 157.0
REGS2_k127_1841674_19 Macro domain protein - - - 0.0000000000000000000000000000000000000321 150.0
REGS2_k127_1841674_2 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 527.0
REGS2_k127_1841674_20 MlaD protein K02067 - - 0.00000000000000000000000000000000002332 150.0
REGS2_k127_1841674_21 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000006108 142.0
REGS2_k127_1841674_22 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000000005226 142.0
REGS2_k127_1841674_23 PFAM EAL domain, GGDEF domain - - - 0.0000000000000000000000000000001657 138.0
REGS2_k127_1841674_24 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000001056 109.0
REGS2_k127_1841674_25 positive regulation of proteasomal protein catabolic process - - - 0.0000000000000000000002163 104.0
REGS2_k127_1841674_26 Domain of unknown function (DUF4340) - - - 0.00000000000000001059 96.0
REGS2_k127_1841674_27 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000001106 80.0
REGS2_k127_1841674_28 Protein of unknown function, DUF255 - - - 0.00000000004249 72.0
REGS2_k127_1841674_29 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000387 59.0
REGS2_k127_1841674_3 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 501.0
REGS2_k127_1841674_30 Putative diguanylate phosphodiesterase - - - 0.0000008202 59.0
REGS2_k127_1841674_31 Protein of unknown function (DUF1499) - - - 0.00008702 45.0
REGS2_k127_1841674_4 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 500.0
REGS2_k127_1841674_5 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 414.0
REGS2_k127_1841674_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 368.0
REGS2_k127_1841674_7 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 351.0
REGS2_k127_1841674_8 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 338.0
REGS2_k127_1841674_9 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005861 291.0
REGS2_k127_186190_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 485.0
REGS2_k127_186190_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 439.0
REGS2_k127_186190_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000009296 119.0
REGS2_k127_1865102_0 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 383.0
REGS2_k127_1865102_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000144 266.0
REGS2_k127_1865102_10 Bacterial membrane protein YfhO - - - 0.000001874 61.0
REGS2_k127_1865102_2 PFAM glycosyl transferase family 39 K14340 - - 0.000000000000000000000000000000000000000000000006324 195.0
REGS2_k127_1865102_3 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000004909 161.0
REGS2_k127_1865102_4 - - - - 0.00000000000000000000000000000000006247 152.0
REGS2_k127_1865102_5 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000001784 150.0
REGS2_k127_1865102_6 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000001079 122.0
REGS2_k127_1865102_7 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000001274 115.0
REGS2_k127_1865102_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000356 95.0
REGS2_k127_1865102_9 Bacterial membrane protein, YfhO - - - 0.000000000000001394 91.0
REGS2_k127_1911049_0 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 331.0
REGS2_k127_1911049_1 Adenylylsulfate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000005859 139.0
REGS2_k127_1911049_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000001389 79.0
REGS2_k127_1927884_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 467.0
REGS2_k127_1927884_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000001594 250.0
REGS2_k127_1927884_2 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000003528 119.0
REGS2_k127_1927884_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000002915 85.0
REGS2_k127_1975985_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 312.0
REGS2_k127_1975985_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 311.0
REGS2_k127_1975985_10 - - - - 0.00000000000000000000000000002914 127.0
REGS2_k127_1975985_11 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000648 96.0
REGS2_k127_1975985_12 Belongs to the UPF0434 family K09791 - - 0.00000000263 61.0
REGS2_k127_1975985_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000001219 61.0
REGS2_k127_1975985_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000308 278.0
REGS2_k127_1975985_3 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000006154 263.0
REGS2_k127_1975985_4 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000002015 265.0
REGS2_k127_1975985_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001022 222.0
REGS2_k127_1975985_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000206 227.0
REGS2_k127_1975985_7 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000004855 193.0
REGS2_k127_1975985_8 O-Antigen ligase K18814 - - 0.000000000000000000000000000000000000000005435 169.0
REGS2_k127_1975985_9 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000006389 152.0
REGS2_k127_1990420_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 559.0
REGS2_k127_1990420_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 458.0
REGS2_k127_1990420_10 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000166 89.0
REGS2_k127_1990420_11 Belongs to the peptidase S8 family K12287 - - 0.00000000000002961 87.0
REGS2_k127_1990420_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000001154 63.0
REGS2_k127_1990420_13 Tetratricopeptide TPR_2 repeat protein - - - 0.000002751 61.0
REGS2_k127_1990420_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 368.0
REGS2_k127_1990420_3 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000649 272.0
REGS2_k127_1990420_4 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000008766 248.0
REGS2_k127_1990420_5 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000000002817 198.0
REGS2_k127_1990420_6 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000006331 179.0
REGS2_k127_1990420_7 arylsulfatase activity - - - 0.00000000000000000000000000000000003406 153.0
REGS2_k127_1990420_8 Glycosyl transferase, family 2 K01854,K07011 - 5.4.99.9 0.0000000000000000000000000000006667 132.0
REGS2_k127_1997923_0 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 485.0
REGS2_k127_1997923_1 protein catabolic process K03420,K13525,K17681 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 373.0
REGS2_k127_1997923_10 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0005392 52.0
REGS2_k127_1997923_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 337.0
REGS2_k127_1997923_3 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 299.0
REGS2_k127_1997923_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000001911 245.0
REGS2_k127_1997923_5 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000000001367 153.0
REGS2_k127_1997923_6 Response regulator, receiver - - - 0.00000000000000000000000002998 113.0
REGS2_k127_1997923_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000015 94.0
REGS2_k127_1997923_8 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000004488 63.0
REGS2_k127_2044826_0 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 431.0
REGS2_k127_2044826_1 Bacterial extracellular solute-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000006138 203.0
REGS2_k127_2044826_2 sulfate transport system, permease K02046 - - 0.00000000000000000000000000000000000000000000001597 193.0
REGS2_k127_2074835_0 beta-lactamase - - - 1.473e-218 728.0
REGS2_k127_2074835_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 7.965e-212 677.0
REGS2_k127_2074835_10 PFAM MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000965 237.0
REGS2_k127_2074835_11 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000001654 203.0
REGS2_k127_2074835_12 BadF/BadG/BcrA/BcrD ATPase family K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.0000000000000000000000000000000000000000000002496 180.0
REGS2_k127_2074835_13 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000004892 169.0
REGS2_k127_2074835_14 YdjC-like protein K02759,K03478 - 2.7.1.196,2.7.1.205,3.5.1.105 0.00000000000000000000000000000000000000003456 161.0
REGS2_k127_2074835_15 TonB dependent receptor - - - 0.00000000000000000000000000000000000006284 155.0
REGS2_k127_2074835_16 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000000009418 140.0
REGS2_k127_2074835_17 Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000003648 133.0
REGS2_k127_2074835_18 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000002314 120.0
REGS2_k127_2074835_19 cheY-homologous receiver domain - - - 0.0000000000000000001889 96.0
REGS2_k127_2074835_2 Ammonium Transporter K03320 - - 3.4e-198 630.0
REGS2_k127_2074835_20 Formate/nitrite transporter K21990,K21993 - - 0.0000000000000001116 87.0
REGS2_k127_2074835_21 TonB dependent receptor - - - 0.00000000000204 76.0
REGS2_k127_2074835_22 - - - - 0.00000000002342 68.0
REGS2_k127_2074835_23 - - - - 0.0000000005234 73.0
REGS2_k127_2074835_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000007761 65.0
REGS2_k127_2074835_25 TonB dependent receptor - - - 0.00000001549 61.0
REGS2_k127_2074835_26 Carboxypeptidase regulatory-like domain - - - 0.000007097 54.0
REGS2_k127_2074835_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 590.0
REGS2_k127_2074835_4 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 469.0
REGS2_k127_2074835_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 461.0
REGS2_k127_2074835_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 419.0
REGS2_k127_2074835_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 407.0
REGS2_k127_2074835_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 325.0
REGS2_k127_2074835_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007223 256.0
REGS2_k127_2102665_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.573e-305 953.0
REGS2_k127_2102665_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 583.0
REGS2_k127_2102665_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000005995 188.0
REGS2_k127_2102665_11 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000006859 175.0
REGS2_k127_2102665_12 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000001087 167.0
REGS2_k127_2102665_13 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000001295 134.0
REGS2_k127_2102665_14 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000002119 99.0
REGS2_k127_2102665_15 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000182 98.0
REGS2_k127_2102665_16 TIGRFAM TonB K03832 - - 0.0000000000000000006188 91.0
REGS2_k127_2102665_17 Sulfotransferase family - - - 0.0000000003225 70.0
REGS2_k127_2102665_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 326.0
REGS2_k127_2102665_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 320.0
REGS2_k127_2102665_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 328.0
REGS2_k127_2102665_5 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004 299.0
REGS2_k127_2102665_6 MoeZ MoeB domain K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000001006 258.0
REGS2_k127_2102665_7 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000001112 238.0
REGS2_k127_2102665_8 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000006375 222.0
REGS2_k127_2102665_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000009055 217.0
REGS2_k127_2132027_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 537.0
REGS2_k127_2132027_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000867 194.0
REGS2_k127_2132027_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001261 150.0
REGS2_k127_2132027_3 ABC-type transport system involved in lipoprotein release permease component K09808,K09815 - - 0.000000000000000000001769 106.0
REGS2_k127_2155580_0 PFAM BMC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007129 266.0
REGS2_k127_2155580_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000003504 247.0
REGS2_k127_2155580_2 PFAM BMC domain - - - 0.00000000000000000000000000000000000000000000000000000000005125 219.0
REGS2_k127_2332657_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 6.611e-285 892.0
REGS2_k127_2332657_1 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
REGS2_k127_2332657_2 YceI-like domain - - - 0.00000000000000000003802 101.0
REGS2_k127_2332657_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000007155 90.0
REGS2_k127_2332657_4 - - - - 0.0000000000003316 82.0
REGS2_k127_2332657_5 Glycosyl transferase, family 2 - - - 0.00004849 48.0
REGS2_k127_2353197_0 ATP hydrolysis coupled proton transport K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000007977 239.0
REGS2_k127_2383478_0 transmembrane transporter activity - - - 0.0 1118.0
REGS2_k127_2383478_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.492e-259 839.0
REGS2_k127_2383478_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000362 123.0
REGS2_k127_2383478_11 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000001329 118.0
REGS2_k127_2383478_12 Sulfurtransferase - - - 0.000000000000000004787 96.0
REGS2_k127_2383478_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000003599 53.0
REGS2_k127_2383478_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 500.0
REGS2_k127_2383478_3 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 428.0
REGS2_k127_2383478_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 406.0
REGS2_k127_2383478_5 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 424.0
REGS2_k127_2383478_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 302.0
REGS2_k127_2383478_7 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001533 286.0
REGS2_k127_2383478_8 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000005699 226.0
REGS2_k127_2383478_9 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000009834 144.0
REGS2_k127_2482308_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1655.0
REGS2_k127_2482308_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 400.0
REGS2_k127_2482308_2 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 396.0
REGS2_k127_2482308_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 382.0
REGS2_k127_2482308_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 370.0
REGS2_k127_2482308_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 309.0
REGS2_k127_2482308_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000351 279.0
REGS2_k127_2482308_7 Universal stress protein K06149 - - 0.00000000000000000003706 96.0
REGS2_k127_2482308_8 Belongs to the universal stress protein A family - - - 0.000000009261 68.0
REGS2_k127_2482308_9 Short repeat of unknown function (DUF308) - - - 0.0000001567 63.0
REGS2_k127_2558576_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1065.0
REGS2_k127_2558576_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.738e-208 657.0
REGS2_k127_2558576_2 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 480.0
REGS2_k127_2558576_3 PFAM peptidase - - - 0.00000000000000000000000000000000000001174 156.0
REGS2_k127_2558576_4 Magnesium chelatase, subunit ChlI K07391 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000001194 85.0
REGS2_k127_2558576_5 SMART Tetratricopeptide - - - 0.0000001179 63.0
REGS2_k127_2622460_0 Hydrolase CocE NonD family - - - 2.021e-318 986.0
REGS2_k127_2622460_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 577.0
REGS2_k127_2622460_10 - - - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
REGS2_k127_2622460_11 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000001834 207.0
REGS2_k127_2622460_12 - - - - 0.000000000000000000000000000000000000000000000000000000002408 205.0
REGS2_k127_2622460_13 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000001169 155.0
REGS2_k127_2622460_14 coenzyme F420 binding K07226 - - 0.0000000000000000000000000000000000001016 147.0
REGS2_k127_2622460_15 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000008562 130.0
REGS2_k127_2622460_16 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000005391 126.0
REGS2_k127_2622460_17 Bacterial PH domain - - - 0.0000000000000000000000000000009225 136.0
REGS2_k127_2622460_18 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000002961 126.0
REGS2_k127_2622460_19 DoxX K15977 - - 0.0000000000000003092 89.0
REGS2_k127_2622460_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 345.0
REGS2_k127_2622460_21 SdpI/YhfL protein family - - - 0.000000008645 61.0
REGS2_k127_2622460_3 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 290.0
REGS2_k127_2622460_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 244.0
REGS2_k127_2622460_5 pfam abc1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000005704 251.0
REGS2_k127_2622460_6 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000002883 228.0
REGS2_k127_2622460_7 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
REGS2_k127_2622460_8 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000003104 216.0
REGS2_k127_2622460_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000007766 216.0
REGS2_k127_263996_0 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 7.047e-257 816.0
REGS2_k127_263996_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 555.0
REGS2_k127_263996_10 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 290.0
REGS2_k127_263996_11 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000007118 246.0
REGS2_k127_263996_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000006452 234.0
REGS2_k127_263996_13 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000008046 230.0
REGS2_k127_263996_14 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000006915 237.0
REGS2_k127_263996_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000009819 228.0
REGS2_k127_263996_16 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000001443 226.0
REGS2_k127_263996_17 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000001094 173.0
REGS2_k127_263996_18 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000001574 155.0
REGS2_k127_263996_19 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000004201 170.0
REGS2_k127_263996_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 525.0
REGS2_k127_263996_20 Thioredoxin K03671 - - 0.00000000000000000000000000000000000003351 145.0
REGS2_k127_263996_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000007896 102.0
REGS2_k127_263996_22 Putative Fe-S cluster K00380 - 1.8.1.2 0.00000000000000000006229 101.0
REGS2_k127_263996_23 Cation efflux family - - - 0.00000000000000002093 90.0
REGS2_k127_263996_24 toxin-antitoxin pair type II binding - - - 0.000000000549 65.0
REGS2_k127_263996_25 protein conserved in bacteria K09931 - - 0.0000006336 61.0
REGS2_k127_263996_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 413.0
REGS2_k127_263996_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 413.0
REGS2_k127_263996_5 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
REGS2_k127_263996_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 321.0
REGS2_k127_263996_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 312.0
REGS2_k127_263996_8 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 312.0
REGS2_k127_263996_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 297.0
REGS2_k127_2652424_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1090.0
REGS2_k127_2652424_1 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1045.0
REGS2_k127_2652424_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001561 240.0
REGS2_k127_2652424_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000003844 240.0
REGS2_k127_2652424_12 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 239.0
REGS2_k127_2652424_13 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005268 248.0
REGS2_k127_2652424_14 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000001817 193.0
REGS2_k127_2652424_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000007223 156.0
REGS2_k127_2652424_16 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000002091 143.0
REGS2_k127_2652424_17 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000144 150.0
REGS2_k127_2652424_18 - - - - 0.00000000000000000000000000000002128 135.0
REGS2_k127_2652424_19 Cupredoxin-like domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000002463 126.0
REGS2_k127_2652424_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 1.329e-205 668.0
REGS2_k127_2652424_20 methyltransferase - - - 0.00000000000000000000000000008429 136.0
REGS2_k127_2652424_21 Aldo Keto reductase - - - 0.0000000000000000002839 91.0
REGS2_k127_2652424_22 - - - - 0.0000000001848 74.0
REGS2_k127_2652424_23 - - - - 0.00000948 50.0
REGS2_k127_2652424_3 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 546.0
REGS2_k127_2652424_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 428.0
REGS2_k127_2652424_5 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 407.0
REGS2_k127_2652424_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 348.0
REGS2_k127_2652424_7 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 339.0
REGS2_k127_2652424_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
REGS2_k127_2652424_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 294.0
REGS2_k127_2656435_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1266.0
REGS2_k127_2656435_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.514e-244 775.0
REGS2_k127_2656435_10 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 332.0
REGS2_k127_2656435_11 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 298.0
REGS2_k127_2656435_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 296.0
REGS2_k127_2656435_13 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001753 292.0
REGS2_k127_2656435_14 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001149 249.0
REGS2_k127_2656435_15 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000008418 169.0
REGS2_k127_2656435_16 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000002745 159.0
REGS2_k127_2656435_17 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000005849 142.0
REGS2_k127_2656435_18 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000003597 133.0
REGS2_k127_2656435_19 Diguanylate cyclase - - - 0.00000000000000000000000000005044 130.0
REGS2_k127_2656435_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 443.0
REGS2_k127_2656435_20 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000006866 124.0
REGS2_k127_2656435_21 von Willebrand factor, type A K07114,K12511 - - 0.0000000000000000000000000002488 135.0
REGS2_k127_2656435_22 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000009474 123.0
REGS2_k127_2656435_23 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000023 113.0
REGS2_k127_2656435_24 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000001208 112.0
REGS2_k127_2656435_25 ig-like, plexins, transcription factors - - - 0.00000000000000000000146 111.0
REGS2_k127_2656435_26 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000002333 96.0
REGS2_k127_2656435_27 Pilus assembly protein, PilO K02664 - - 0.0000000000000000001311 97.0
REGS2_k127_2656435_28 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000001964 87.0
REGS2_k127_2656435_29 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000005941 86.0
REGS2_k127_2656435_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 435.0
REGS2_k127_2656435_30 chaperone-mediated protein folding - - - 0.00000000000001719 89.0
REGS2_k127_2656435_31 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000001849 83.0
REGS2_k127_2656435_32 Roadblock/LC7 domain - - - 0.0000000000007358 74.0
REGS2_k127_2656435_33 Tetratricopeptide repeat - - - 0.000000000003665 78.0
REGS2_k127_2656435_34 Protein of unknown function (FYDLN_acid) - - - 0.000000008144 68.0
REGS2_k127_2656435_35 Tetratricopeptide repeat - - - 0.00000004277 65.0
REGS2_k127_2656435_37 Peptidase M56 - - - 0.0007065 54.0
REGS2_k127_2656435_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 409.0
REGS2_k127_2656435_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 387.0
REGS2_k127_2656435_6 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 361.0
REGS2_k127_2656435_7 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 336.0
REGS2_k127_2656435_8 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 331.0
REGS2_k127_2656435_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 324.0
REGS2_k127_2658616_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007854 262.0
REGS2_k127_2658616_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000009707 258.0
REGS2_k127_2658616_2 TIGRFAM N-carbamoylputrescine amidase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000004768 198.0
REGS2_k127_2658616_3 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000007949 200.0
REGS2_k127_2684226_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 473.0
REGS2_k127_2684226_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 336.0
REGS2_k127_2684226_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000009928 70.0
REGS2_k127_2684226_11 Helix-turn-helix - - - 0.00000014 60.0
REGS2_k127_2684226_12 NB-ARC domain - - - 0.0001089 54.0
REGS2_k127_2684226_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 317.0
REGS2_k127_2684226_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001086 281.0
REGS2_k127_2684226_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001053 301.0
REGS2_k127_2684226_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000392 275.0
REGS2_k127_2684226_6 Transport permease protein K09690 - - 0.000000000000000000000000000000005571 138.0
REGS2_k127_2684226_7 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000001126 129.0
REGS2_k127_2684226_8 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000002684 109.0
REGS2_k127_2684226_9 Phosphoribosyl transferase domain - - - 0.0000000000000000015 95.0
REGS2_k127_2687548_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.866e-195 659.0
REGS2_k127_2687548_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 518.0
REGS2_k127_2687548_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 330.0
REGS2_k127_2687548_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
REGS2_k127_2687548_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000001919 243.0
REGS2_k127_2687548_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000003938 218.0
REGS2_k127_2687548_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000002169 130.0
REGS2_k127_2687548_7 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000001574 112.0
REGS2_k127_2687548_8 PFAM YbbR-like protein - - - 0.000000000000000001875 94.0
REGS2_k127_2721946_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 499.0
REGS2_k127_2721946_1 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
REGS2_k127_2721946_10 OsmC-like protein - - - 0.0000000001746 66.0
REGS2_k127_2721946_11 - - - - 0.000000001535 68.0
REGS2_k127_2721946_12 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000122 69.0
REGS2_k127_2721946_13 Zn-dependent protease - - - 0.000002301 61.0
REGS2_k127_2721946_14 cytochrome P450 - - - 0.00002329 54.0
REGS2_k127_2721946_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004822 257.0
REGS2_k127_2721946_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000002875 190.0
REGS2_k127_2721946_4 Cytochrome P450 - - - 0.000000000000000000000000000000000000002311 151.0
REGS2_k127_2721946_5 - K01286 - 3.4.16.4 0.00000000000000000000000000000000000004307 166.0
REGS2_k127_2721946_6 Penicillinase repressor - - - 0.000000000000000000000000000000000002553 141.0
REGS2_k127_2721946_7 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000001826 140.0
REGS2_k127_2721946_8 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000000000000000000000003073 126.0
REGS2_k127_2721946_9 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000008225 102.0
REGS2_k127_2747196_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 2.203e-267 840.0
REGS2_k127_2747196_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000004674 183.0
REGS2_k127_2753185_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 7.353e-201 657.0
REGS2_k127_2753185_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 541.0
REGS2_k127_2753185_10 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000002363 224.0
REGS2_k127_2753185_11 Large extracellular alpha-helical protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000002617 233.0
REGS2_k127_2753185_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000616 203.0
REGS2_k127_2753185_13 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000009177 201.0
REGS2_k127_2753185_14 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000001145 167.0
REGS2_k127_2753185_15 Flavoprotein K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000008357 153.0
REGS2_k127_2753185_16 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000004188 152.0
REGS2_k127_2753185_17 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000001627 126.0
REGS2_k127_2753185_18 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.00000000000000000000000000005398 121.0
REGS2_k127_2753185_19 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000000005691 121.0
REGS2_k127_2753185_2 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 451.0
REGS2_k127_2753185_20 YqeY-like protein K09117 - - 0.000000000000000000000000002502 127.0
REGS2_k127_2753185_21 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000003644 112.0
REGS2_k127_2753185_22 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002405 91.0
REGS2_k127_2753185_23 YGGT family K02221 - - 0.0000000000000000003279 94.0
REGS2_k127_2753185_24 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.0000000000000001073 85.0
REGS2_k127_2753185_25 PFAM DivIVA family protein K04074 - - 0.0000000000000002433 85.0
REGS2_k127_2753185_26 C4-type zinc ribbon domain K07164 - - 0.0000000000001253 79.0
REGS2_k127_2753185_27 nuclear chromosome segregation - - - 0.000000000004756 78.0
REGS2_k127_2753185_29 - - - - 0.00002173 54.0
REGS2_k127_2753185_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 372.0
REGS2_k127_2753185_4 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 355.0
REGS2_k127_2753185_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 338.0
REGS2_k127_2753185_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 291.0
REGS2_k127_2753185_7 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000006363 266.0
REGS2_k127_2753185_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001229 271.0
REGS2_k127_2753185_9 Protein of unknown function (DUF1190) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004231 243.0
REGS2_k127_2805540_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000003631 146.0
REGS2_k127_2805540_1 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000003558 123.0
REGS2_k127_3012325_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 606.0
REGS2_k127_3012325_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 498.0
REGS2_k127_3012325_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 257.0
REGS2_k127_3012325_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000005632 213.0
REGS2_k127_3012325_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001244 205.0
REGS2_k127_3012325_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006423 204.0
REGS2_k127_3012325_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000001235 185.0
REGS2_k127_3012325_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000001468 203.0
REGS2_k127_3012325_16 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000003413 180.0
REGS2_k127_3012325_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000002583 175.0
REGS2_k127_3012325_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000001171 175.0
REGS2_k127_3012325_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000005349 173.0
REGS2_k127_3012325_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 437.0
REGS2_k127_3012325_20 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000006796 167.0
REGS2_k127_3012325_21 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001005 166.0
REGS2_k127_3012325_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000489 155.0
REGS2_k127_3012325_23 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000006685 152.0
REGS2_k127_3012325_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000003307 141.0
REGS2_k127_3012325_25 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000005444 150.0
REGS2_k127_3012325_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000001189 136.0
REGS2_k127_3012325_27 structural constituent of ribosome K02879 - - 0.000000000000000000000000000008536 127.0
REGS2_k127_3012325_28 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000009166 115.0
REGS2_k127_3012325_29 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001069 119.0
REGS2_k127_3012325_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 401.0
REGS2_k127_3012325_30 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000004194 115.0
REGS2_k127_3012325_31 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000663 98.0
REGS2_k127_3012325_32 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000003369 91.0
REGS2_k127_3012325_33 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000072 68.0
REGS2_k127_3012325_34 ribosomal protein l30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000004256 66.0
REGS2_k127_3012325_35 PFAM VanZ like - - - 0.0000006321 57.0
REGS2_k127_3012325_36 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000004131 53.0
REGS2_k127_3012325_37 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00004338 53.0
REGS2_k127_3012325_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 326.0
REGS2_k127_3012325_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 303.0
REGS2_k127_3012325_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001643 277.0
REGS2_k127_3012325_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009245 272.0
REGS2_k127_3012325_8 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001971 274.0
REGS2_k127_3012325_9 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001171 278.0
REGS2_k127_3155683_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 569.0
REGS2_k127_3155683_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 348.0
REGS2_k127_3155683_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000003695 192.0
REGS2_k127_3155683_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000007823 108.0
REGS2_k127_3155683_4 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.000000000000000000000261 107.0
REGS2_k127_323919_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.211e-218 696.0
REGS2_k127_323919_1 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000879 280.0
REGS2_k127_323919_10 protein conserved in bacteria K09778 - - 0.00000000000000000000000000000000004843 148.0
REGS2_k127_323919_11 oxidoreductase activity - - - 0.0000141 57.0
REGS2_k127_323919_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000008946 256.0
REGS2_k127_323919_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
REGS2_k127_323919_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000003729 235.0
REGS2_k127_323919_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000002017 222.0
REGS2_k127_323919_6 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000005345 190.0
REGS2_k127_323919_7 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000001192 181.0
REGS2_k127_323919_8 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000002286 192.0
REGS2_k127_323919_9 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000000002684 160.0
REGS2_k127_3325622_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 350.0
REGS2_k127_3325622_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002312 255.0
REGS2_k127_3325622_10 AMP binding - - - 0.00000000000003074 87.0
REGS2_k127_3325622_11 energy transducer activity K03832 - - 0.0000000003446 69.0
REGS2_k127_3325622_2 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000329 263.0
REGS2_k127_3325622_3 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001074 256.0
REGS2_k127_3325622_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000005926 239.0
REGS2_k127_3325622_5 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
REGS2_k127_3325622_6 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000001052 226.0
REGS2_k127_3325622_7 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001068 215.0
REGS2_k127_3325622_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001647 231.0
REGS2_k127_3325622_9 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000002944 151.0
REGS2_k127_3404192_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1140.0
REGS2_k127_3404192_1 Peptidase family M13 K07386 - - 4.33e-216 693.0
REGS2_k127_3404192_10 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000002158 169.0
REGS2_k127_3404192_11 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000000000005671 112.0
REGS2_k127_3404192_12 General secretory system II protein E domain protein K02652 - - 0.00000000000003995 84.0
REGS2_k127_3404192_13 antisigma factor binding - - - 0.0000000000001252 76.0
REGS2_k127_3404192_2 Peptidase family M13 K07386 - - 5.112e-210 677.0
REGS2_k127_3404192_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 595.0
REGS2_k127_3404192_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 539.0
REGS2_k127_3404192_5 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 374.0
REGS2_k127_3404192_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000001518 235.0
REGS2_k127_3404192_7 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000007681 220.0
REGS2_k127_3404192_8 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000001801 214.0
REGS2_k127_3404192_9 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000001395 192.0
REGS2_k127_3455755_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1603.0
REGS2_k127_3455755_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1490.0
REGS2_k127_3455755_10 NAD-dependent epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 377.0
REGS2_k127_3455755_11 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 368.0
REGS2_k127_3455755_12 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 301.0
REGS2_k127_3455755_13 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007539 268.0
REGS2_k127_3455755_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002154 268.0
REGS2_k127_3455755_15 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002809 268.0
REGS2_k127_3455755_16 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 228.0
REGS2_k127_3455755_17 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003585 221.0
REGS2_k127_3455755_18 PFAM sugar transferase K13012 - - 0.000000000000000000000000000000000000000000000000000000000009321 227.0
REGS2_k127_3455755_19 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000001341 224.0
REGS2_k127_3455755_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.299e-253 814.0
REGS2_k127_3455755_20 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000005568 203.0
REGS2_k127_3455755_21 Glycosyl transferases group 1 K21001 - - 0.000000000000000000000000000000000000007147 162.0
REGS2_k127_3455755_22 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000001807 145.0
REGS2_k127_3455755_23 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000008391 126.0
REGS2_k127_3455755_24 - - - - 0.000000002638 70.0
REGS2_k127_3455755_25 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000003068 51.0
REGS2_k127_3455755_26 O-Antigen ligase - - - 0.000364 55.0
REGS2_k127_3455755_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.689e-245 767.0
REGS2_k127_3455755_4 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 576.0
REGS2_k127_3455755_5 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 577.0
REGS2_k127_3455755_6 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 543.0
REGS2_k127_3455755_7 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 463.0
REGS2_k127_3455755_8 RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 464.0
REGS2_k127_3455755_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 429.0
REGS2_k127_3470271_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.63e-224 707.0
REGS2_k127_3470271_1 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 331.0
REGS2_k127_3470271_2 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002616 259.0
REGS2_k127_3470271_3 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000006645 233.0
REGS2_k127_3470271_4 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
REGS2_k127_3470271_5 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000007137 117.0
REGS2_k127_3470271_6 catalyzes the conversion of K17723 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0051536,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.0000000003617 65.0
REGS2_k127_3474895_0 DEAD DEAH box helicase K03724 - - 0.0 1307.0
REGS2_k127_3474895_1 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 546.0
REGS2_k127_3474895_10 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000000000001369 147.0
REGS2_k127_3474895_11 synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000258 149.0
REGS2_k127_3474895_12 Dodecin K09165 - - 0.00000000000000000000002062 101.0
REGS2_k127_3474895_13 - - - - 0.000000000000001415 88.0
REGS2_k127_3474895_14 SnoaL-like domain - - - 0.00002074 52.0
REGS2_k127_3474895_15 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.0004177 51.0
REGS2_k127_3474895_16 transcriptional regulator - - - 0.0006157 42.0
REGS2_k127_3474895_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 323.0
REGS2_k127_3474895_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000001816 263.0
REGS2_k127_3474895_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
REGS2_k127_3474895_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000002402 218.0
REGS2_k127_3474895_6 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.00000000000000000000000000000000000000000000000000000006906 203.0
REGS2_k127_3474895_7 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000000000000000000000008652 205.0
REGS2_k127_3474895_8 - - - - 0.0000000000000000000000000000000000000000000004322 184.0
REGS2_k127_3474895_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.0000000000000000000000000000000000000000002504 173.0
REGS2_k127_3489132_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 512.0
REGS2_k127_3489132_1 Mandelate racemase muconate lactonizing enzyme K02549,K19802 - 4.2.1.113,5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 408.0
REGS2_k127_3489132_10 PFAM Integrase catalytic region - - - 0.000000000000004307 77.0
REGS2_k127_3489132_11 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000006282 71.0
REGS2_k127_3489132_12 domain, Protein - - - 0.0000001665 62.0
REGS2_k127_3489132_13 Transmembrane and TPR repeat-containing protein 1 - - - 0.0001148 55.0
REGS2_k127_3489132_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 402.0
REGS2_k127_3489132_3 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 322.0
REGS2_k127_3489132_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 323.0
REGS2_k127_3489132_5 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002903 250.0
REGS2_k127_3489132_6 Integrase core domain - - - 0.00000000000000000000000000000000000002922 154.0
REGS2_k127_3489132_7 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000003613 155.0
REGS2_k127_3489132_8 response regulator - - - 0.000000000000000000000002038 115.0
REGS2_k127_3489132_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000002494 109.0
REGS2_k127_3513801_0 Amylo-alpha-1,6-glucosidase - - - 4.131e-238 752.0
REGS2_k127_3513801_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 5.68e-199 637.0
REGS2_k127_3513801_10 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000007698 160.0
REGS2_k127_3513801_11 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000001053 161.0
REGS2_k127_3513801_13 peroxiredoxin activity - - - 0.0000000000000001005 86.0
REGS2_k127_3513801_14 Secretin and TonB N terminus short domain K02666 - - 0.000000000000003806 80.0
REGS2_k127_3513801_15 ubiE/COQ5 methyltransferase family - - - 0.000000000000005238 84.0
REGS2_k127_3513801_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 586.0
REGS2_k127_3513801_3 magnesium chelatase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 572.0
REGS2_k127_3513801_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 443.0
REGS2_k127_3513801_5 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 376.0
REGS2_k127_3513801_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 337.0
REGS2_k127_3513801_7 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000000000000000000001236 263.0
REGS2_k127_3513801_8 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000006726 198.0
REGS2_k127_3513801_9 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000001388 197.0
REGS2_k127_3529255_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 491.0
REGS2_k127_3529255_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 499.0
REGS2_k127_3529255_10 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000001383 119.0
REGS2_k127_3529255_2 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 422.0
REGS2_k127_3529255_3 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 385.0
REGS2_k127_3529255_4 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 330.0
REGS2_k127_3529255_5 carbohydrate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 318.0
REGS2_k127_3529255_6 Formyl transferase K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004292 291.0
REGS2_k127_3529255_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001166 247.0
REGS2_k127_3529255_8 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000447 228.0
REGS2_k127_3529255_9 PFAM ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000007328 153.0
REGS2_k127_3573049_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 501.0
REGS2_k127_3573049_1 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 458.0
REGS2_k127_3573049_2 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 300.0
REGS2_k127_3573049_3 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000004603 147.0
REGS2_k127_3573049_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000002905 130.0
REGS2_k127_3573049_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000002025 117.0
REGS2_k127_3592326_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1427.0
REGS2_k127_3628433_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 507.0
REGS2_k127_3628433_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 421.0
REGS2_k127_3628433_10 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000886 206.0
REGS2_k127_3628433_11 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000606 192.0
REGS2_k127_3628433_12 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000003228 154.0
REGS2_k127_3628433_13 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000001371 114.0
REGS2_k127_3628433_14 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000004471 105.0
REGS2_k127_3628433_15 Phosphotransferase System K11189 - - 0.000000000000000000005938 102.0
REGS2_k127_3628433_16 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000002127 98.0
REGS2_k127_3628433_17 lipopolysaccharide transport K09774 - - 0.000000163 66.0
REGS2_k127_3628433_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 371.0
REGS2_k127_3628433_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 372.0
REGS2_k127_3628433_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 368.0
REGS2_k127_3628433_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 315.0
REGS2_k127_3628433_6 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
REGS2_k127_3628433_7 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 326.0
REGS2_k127_3628433_8 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 293.0
REGS2_k127_3628433_9 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 287.0
REGS2_k127_3711759_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 2.019e-197 647.0
REGS2_k127_3711759_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.963e-196 622.0
REGS2_k127_3711759_10 Protein of unknown function (DUF1059) - - - 0.0000000000000000002629 88.0
REGS2_k127_3711759_11 phosphohistidine phosphatase, SixA - - - 0.000000000000002941 84.0
REGS2_k127_3711759_12 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.00000000000002402 72.0
REGS2_k127_3711759_13 Phospholipase/Carboxylesterase - - - 0.0000000001979 62.0
REGS2_k127_3711759_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 420.0
REGS2_k127_3711759_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 337.0
REGS2_k127_3711759_4 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000002709 243.0
REGS2_k127_3711759_5 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001716 229.0
REGS2_k127_3711759_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000006274 220.0
REGS2_k127_3711759_7 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000003906 176.0
REGS2_k127_3711759_8 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000000001361 171.0
REGS2_k127_3711759_9 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000009296 151.0
REGS2_k127_3763337_0 Methionine synthase K00548 - 2.1.1.13 0.0 1298.0
REGS2_k127_3763337_1 cellulose binding - - - 2.751e-222 728.0
REGS2_k127_3763337_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 438.0
REGS2_k127_3763337_11 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 388.0
REGS2_k127_3763337_12 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 393.0
REGS2_k127_3763337_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 377.0
REGS2_k127_3763337_14 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 314.0
REGS2_k127_3763337_15 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 308.0
REGS2_k127_3763337_16 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02049,K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 311.0
REGS2_k127_3763337_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 308.0
REGS2_k127_3763337_18 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004732 278.0
REGS2_k127_3763337_19 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001351 280.0
REGS2_k127_3763337_2 Domain of unknown function (DUF4070) - - - 2.672e-221 698.0
REGS2_k127_3763337_20 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007395 284.0
REGS2_k127_3763337_21 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 271.0
REGS2_k127_3763337_22 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 261.0
REGS2_k127_3763337_23 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002525 254.0
REGS2_k127_3763337_24 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008104 238.0
REGS2_k127_3763337_25 Squalene/phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000000000004473 231.0
REGS2_k127_3763337_26 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000005316 213.0
REGS2_k127_3763337_27 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000007893 211.0
REGS2_k127_3763337_28 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000000000000000000001607 209.0
REGS2_k127_3763337_29 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000104 186.0
REGS2_k127_3763337_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.996e-219 710.0
REGS2_k127_3763337_30 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000000005214 187.0
REGS2_k127_3763337_31 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000001752 183.0
REGS2_k127_3763337_32 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.0000000000000000000000000000000000000000000662 164.0
REGS2_k127_3763337_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000001019 156.0
REGS2_k127_3763337_34 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000000000000000001096 141.0
REGS2_k127_3763337_35 Citrate transporter - - - 0.00000000000000000000000000000000002193 149.0
REGS2_k127_3763337_36 ligase activity - - - 0.00000000000000000000000000000000007827 145.0
REGS2_k127_3763337_37 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000009752 137.0
REGS2_k127_3763337_38 DinB family - - - 0.0000000000000000000000000000000002566 149.0
REGS2_k127_3763337_39 protein trimerization K02453 - - 0.00000000000000000000000003822 113.0
REGS2_k127_3763337_4 Radical SAM - - - 2.461e-218 699.0
REGS2_k127_3763337_40 transcriptional regulator, ArsR family - - - 0.000000000000000000000002822 106.0
REGS2_k127_3763337_41 lysyltransferase activity K07027 - - 0.000000000000000008071 98.0
REGS2_k127_3763337_42 - - - - 0.0000000000001138 72.0
REGS2_k127_3763337_43 Cyclase family - - - 0.000000001458 69.0
REGS2_k127_3763337_44 Phosphorylase superfamily K01243 - 3.2.2.9 0.000006713 57.0
REGS2_k127_3763337_45 metallopeptidase activity - - - 0.00002534 52.0
REGS2_k127_3763337_46 PFAM Outer membrane efflux protein - - - 0.0001618 54.0
REGS2_k127_3763337_5 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 4.681e-214 694.0
REGS2_k127_3763337_6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.406e-212 670.0
REGS2_k127_3763337_7 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 2.718e-203 641.0
REGS2_k127_3763337_8 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 591.0
REGS2_k127_3763337_9 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 600.0
REGS2_k127_3802282_0 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 554.0
REGS2_k127_3802282_1 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 484.0
REGS2_k127_3802282_10 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
REGS2_k127_3802282_11 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004611 270.0
REGS2_k127_3802282_12 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
REGS2_k127_3802282_13 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002871 258.0
REGS2_k127_3802282_14 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000003426 243.0
REGS2_k127_3802282_15 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
REGS2_k127_3802282_16 transport system permease K01998 - - 0.0000000000000000000000000000000000000000000000000000000004138 226.0
REGS2_k127_3802282_17 - - - - 0.00000000000001046 77.0
REGS2_k127_3802282_18 OsmC-like protein - - - 0.0000000000002213 73.0
REGS2_k127_3802282_19 - - - - 0.00003638 56.0
REGS2_k127_3802282_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 462.0
REGS2_k127_3802282_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 420.0
REGS2_k127_3802282_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 366.0
REGS2_k127_3802282_5 Major facilitator K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 362.0
REGS2_k127_3802282_6 PFAM Major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 349.0
REGS2_k127_3802282_7 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 288.0
REGS2_k127_3802282_8 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002856 281.0
REGS2_k127_3802282_9 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002275 280.0
REGS2_k127_381262_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 562.0
REGS2_k127_381262_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 520.0
REGS2_k127_381262_10 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000004242 130.0
REGS2_k127_381262_12 TIGRFAM TonB family protein K03832 - - 0.00001553 55.0
REGS2_k127_381262_13 - - - - 0.00008799 55.0
REGS2_k127_381262_2 Glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 356.0
REGS2_k127_381262_3 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 359.0
REGS2_k127_381262_4 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001287 276.0
REGS2_k127_381262_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000001286 255.0
REGS2_k127_381262_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000429 211.0
REGS2_k127_381262_7 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000003917 213.0
REGS2_k127_381262_8 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000006797 199.0
REGS2_k127_381262_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000003512 137.0
REGS2_k127_3832115_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 354.0
REGS2_k127_3832115_1 twitching motility protein K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 349.0
REGS2_k127_3832115_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000001314 222.0
REGS2_k127_3832115_3 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000195 168.0
REGS2_k127_3832115_4 Bacterial membrane protein, YfhO - - - 0.000000000000002988 78.0
REGS2_k127_3832115_5 protein transport across the cell outer membrane K02246,K08084 - - 0.0002051 52.0
REGS2_k127_3854566_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 488.0
REGS2_k127_3854566_1 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 428.0
REGS2_k127_3854566_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008464 281.0
REGS2_k127_3854566_3 ASPIC and UnbV - - - 0.00000000000000000003577 103.0
REGS2_k127_3857130_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.956e-267 850.0
REGS2_k127_3857130_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.272e-237 757.0
REGS2_k127_3857130_10 - - - - 0.000000000000000000000000000000000000000000000002232 185.0
REGS2_k127_3857130_11 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.00000000000000000000000000000006324 132.0
REGS2_k127_3857130_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000003181 133.0
REGS2_k127_3857130_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000000005085 85.0
REGS2_k127_3857130_14 protein N-acetylglucosaminyltransferase activity K09580,K09667 - 2.4.1.255,5.3.4.1 0.00000000000001043 87.0
REGS2_k127_3857130_15 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000001935 80.0
REGS2_k127_3857130_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000003562 71.0
REGS2_k127_3857130_17 SMART Rhodanese domain protein - - - 0.0000000002899 61.0
REGS2_k127_3857130_18 protein conserved in bacteria K09928 - - 0.000000002141 69.0
REGS2_k127_3857130_19 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 0.00002409 54.0
REGS2_k127_3857130_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 363.0
REGS2_k127_3857130_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 321.0
REGS2_k127_3857130_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 306.0
REGS2_k127_3857130_5 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 306.0
REGS2_k127_3857130_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005471 254.0
REGS2_k127_3857130_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000002279 233.0
REGS2_k127_3857130_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000003038 198.0
REGS2_k127_3857130_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000002489 197.0
REGS2_k127_3873896_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 473.0
REGS2_k127_3873896_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 324.0
REGS2_k127_3873896_2 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000001574 100.0
REGS2_k127_3913051_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 529.0
REGS2_k127_3913051_1 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 395.0
REGS2_k127_3913051_10 GtrA-like protein K00995 - 2.7.8.5 0.000000000000000000000000001021 123.0
REGS2_k127_3913051_11 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000009932 118.0
REGS2_k127_3913051_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000003237 114.0
REGS2_k127_3913051_13 metal ion transmembrane transporter activity - - - 0.00000000000000002874 87.0
REGS2_k127_3913051_14 Predicted membrane protein (DUF2127) - - - 0.0000000000001113 78.0
REGS2_k127_3913051_15 protein secretion K03116 GO:0008150,GO:0040007 - 0.0000000000004809 71.0
REGS2_k127_3913051_16 - - - - 0.000000000001003 72.0
REGS2_k127_3913051_2 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 394.0
REGS2_k127_3913051_3 Acetamidase formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 334.0
REGS2_k127_3913051_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 320.0
REGS2_k127_3913051_5 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006922 266.0
REGS2_k127_3913051_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001378 258.0
REGS2_k127_3913051_7 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000004599 212.0
REGS2_k127_3913051_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000004455 204.0
REGS2_k127_3913051_9 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000003145 139.0
REGS2_k127_3931900_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 471.0
REGS2_k127_3931900_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 427.0
REGS2_k127_3931900_10 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000002187 155.0
REGS2_k127_3931900_11 Hfq protein - - - 0.000000000000000000000000000002297 124.0
REGS2_k127_3931900_12 Glycosyl transferase - - - 0.000000000000000000000000001816 124.0
REGS2_k127_3931900_13 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000006035 112.0
REGS2_k127_3931900_14 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000001001 113.0
REGS2_k127_3931900_15 peptidase activity - - - 0.00000000000000000168 94.0
REGS2_k127_3931900_16 peptidase inhibitor activity - - - 0.00000000000003946 87.0
REGS2_k127_3931900_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 423.0
REGS2_k127_3931900_3 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 399.0
REGS2_k127_3931900_4 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 338.0
REGS2_k127_3931900_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000577 286.0
REGS2_k127_3931900_6 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003597 260.0
REGS2_k127_3931900_7 xanthine dehydrogenase activity K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000438 222.0
REGS2_k127_3931900_8 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000004216 199.0
REGS2_k127_3931900_9 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000002119 197.0
REGS2_k127_3971366_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1204.0
REGS2_k127_3971366_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.219e-291 916.0
REGS2_k127_3971366_10 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000002503 225.0
REGS2_k127_3971366_11 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000005578 207.0
REGS2_k127_3971366_12 histidine kinase, HAMP K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000178 203.0
REGS2_k127_3971366_13 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000007242 190.0
REGS2_k127_3971366_14 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000001653 174.0
REGS2_k127_3971366_15 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000002404 176.0
REGS2_k127_3971366_16 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K07010 - - 0.0000000000000000000000000000000000000000002961 166.0
REGS2_k127_3971366_17 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000001823 147.0
REGS2_k127_3971366_18 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000282 119.0
REGS2_k127_3971366_19 - - - - 0.0000000000000000000000000001411 119.0
REGS2_k127_3971366_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 424.0
REGS2_k127_3971366_20 Metallo-beta-lactamase superfamily - - - 0.000000000000000000004809 106.0
REGS2_k127_3971366_21 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000002185 101.0
REGS2_k127_3971366_22 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.00000000000000003631 88.0
REGS2_k127_3971366_23 Tellurite resistance protein TerB - - - 0.000000000000002581 84.0
REGS2_k127_3971366_24 DinB superfamily - - - 0.0000000000008086 75.0
REGS2_k127_3971366_25 AMP binding - - - 0.00000000002112 71.0
REGS2_k127_3971366_26 C4-type zinc ribbon domain K07164 - - 0.0000004526 59.0
REGS2_k127_3971366_27 PFAM Universal stress protein family - - - 0.0000007428 58.0
REGS2_k127_3971366_28 AraC-like ligand binding domain - - - 0.000005261 53.0
REGS2_k127_3971366_29 Helix-turn-helix domain K02806 - - 0.000008518 51.0
REGS2_k127_3971366_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 426.0
REGS2_k127_3971366_30 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0004719 48.0
REGS2_k127_3971366_4 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 332.0
REGS2_k127_3971366_5 short-chain dehydrogenase K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000646 273.0
REGS2_k127_3971366_6 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000077 262.0
REGS2_k127_3971366_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001198 241.0
REGS2_k127_3971366_8 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000003086 238.0
REGS2_k127_3971366_9 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000002428 245.0
REGS2_k127_3972996_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1195.0
REGS2_k127_3972996_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 593.0
REGS2_k127_3972996_10 - - - - 0.000000000000000000000000000000000616 151.0
REGS2_k127_3972996_11 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000001477 138.0
REGS2_k127_3972996_12 Hemerythrin - - - 0.0000000000000000000001266 107.0
REGS2_k127_3972996_13 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000004634 100.0
REGS2_k127_3972996_14 Protein of unknown function (DUF1326) - - - 0.000000000000000002174 90.0
REGS2_k127_3972996_15 With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate K03154 - - 0.00000000000000001796 84.0
REGS2_k127_3972996_2 PAS fold-4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 533.0
REGS2_k127_3972996_3 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 461.0
REGS2_k127_3972996_4 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 381.0
REGS2_k127_3972996_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000001311 267.0
REGS2_k127_3972996_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000008571 215.0
REGS2_k127_3972996_7 Ku70/Ku80 beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000008467 205.0
REGS2_k127_3972996_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000004393 178.0
REGS2_k127_4039060_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 2.319e-319 1014.0
REGS2_k127_4039060_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 568.0
REGS2_k127_4039060_10 Tetratricopeptide repeat - - - 0.000000000000000001876 95.0
REGS2_k127_4039060_11 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000003359 97.0
REGS2_k127_4039060_13 Tetratricopeptide repeat - - - 0.0000000004608 65.0
REGS2_k127_4039060_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 537.0
REGS2_k127_4039060_3 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 395.0
REGS2_k127_4039060_4 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 358.0
REGS2_k127_4039060_5 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 345.0
REGS2_k127_4039060_6 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000587 252.0
REGS2_k127_4039060_7 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000006501 239.0
REGS2_k127_4039060_8 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000001868 210.0
REGS2_k127_4039060_9 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000005396 136.0
REGS2_k127_404902_0 Heat shock 70 kDa protein K04043 - - 6.398e-303 940.0
REGS2_k127_404902_1 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 1.562e-254 799.0
REGS2_k127_404902_10 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 433.0
REGS2_k127_404902_11 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 410.0
REGS2_k127_404902_12 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 395.0
REGS2_k127_404902_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 389.0
REGS2_k127_404902_14 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 388.0
REGS2_k127_404902_15 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 382.0
REGS2_k127_404902_16 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 395.0
REGS2_k127_404902_17 fumarate reductase K00240 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 353.0
REGS2_k127_404902_18 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 316.0
REGS2_k127_404902_19 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 321.0
REGS2_k127_404902_2 Carboxypeptidase regulatory-like domain - - - 8.601e-245 790.0
REGS2_k127_404902_20 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 299.0
REGS2_k127_404902_21 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000311 312.0
REGS2_k127_404902_22 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000003578 266.0
REGS2_k127_404902_23 PFAM Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000002035 260.0
REGS2_k127_404902_24 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000007187 252.0
REGS2_k127_404902_25 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004378 258.0
REGS2_k127_404902_26 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000000000006305 244.0
REGS2_k127_404902_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000005137 241.0
REGS2_k127_404902_28 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000008178 216.0
REGS2_k127_404902_29 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000004606 222.0
REGS2_k127_404902_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.384e-200 638.0
REGS2_k127_404902_30 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000000000000001885 201.0
REGS2_k127_404902_31 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000003516 211.0
REGS2_k127_404902_32 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000004393 199.0
REGS2_k127_404902_33 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000002108 183.0
REGS2_k127_404902_34 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000003051 178.0
REGS2_k127_404902_35 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000006786 169.0
REGS2_k127_404902_36 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.00000000000000000000000000000000000000000002346 170.0
REGS2_k127_404902_37 Peptidase M23 - - - 0.00000000000000000000000000000000000000000217 170.0
REGS2_k127_404902_38 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000001881 168.0
REGS2_k127_404902_39 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000119 160.0
REGS2_k127_404902_4 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 535.0
REGS2_k127_404902_40 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000001394 143.0
REGS2_k127_404902_41 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000004004 141.0
REGS2_k127_404902_42 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000006798 132.0
REGS2_k127_404902_43 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000528 122.0
REGS2_k127_404902_44 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000004917 127.0
REGS2_k127_404902_45 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000001206 108.0
REGS2_k127_404902_46 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000004092 111.0
REGS2_k127_404902_47 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000000306 104.0
REGS2_k127_404902_48 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000001064 104.0
REGS2_k127_404902_49 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000009701 107.0
REGS2_k127_404902_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 499.0
REGS2_k127_404902_50 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000005476 95.0
REGS2_k127_404902_51 Tetratricopeptide repeat K08309 - - 0.00000000000038 83.0
REGS2_k127_404902_52 Pyruvate phosphate dikinase - - - 0.0000000000006943 78.0
REGS2_k127_404902_53 histone H2A K63-linked ubiquitination - - - 0.000000000001154 81.0
REGS2_k127_404902_54 Alg9-like mannosyltransferase family - - - 0.00000000003104 76.0
REGS2_k127_404902_55 oxidoreductase activity - - - 0.0000000005891 72.0
REGS2_k127_404902_56 Domain of unknown function (DUF1844) - - - 0.0000002265 63.0
REGS2_k127_404902_57 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001033 62.0
REGS2_k127_404902_58 Domain of unknown function (DUF4388) - - - 0.00001629 57.0
REGS2_k127_404902_59 Tetratricopeptide repeat - - - 0.0004327 53.0
REGS2_k127_404902_6 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 480.0
REGS2_k127_404902_7 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 439.0
REGS2_k127_404902_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 422.0
REGS2_k127_404902_9 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 415.0
REGS2_k127_4097875_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.27e-291 903.0
REGS2_k127_4097875_1 Domain of unknown function (DUF5009) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 299.0
REGS2_k127_4097875_2 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005646 268.0
REGS2_k127_4097875_3 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000004334 240.0
REGS2_k127_4097875_4 Belongs to the UPF0403 family - - - 0.00000000000000000000000000000000000000001251 157.0
REGS2_k127_4097875_5 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0000000002608 68.0
REGS2_k127_4097875_6 COGs COG1748 Saccharopine dehydrogenase and related protein - - - 0.000003815 50.0
REGS2_k127_4128104_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.641e-265 837.0
REGS2_k127_4128104_1 PFAM Type II secretion system protein E K02652 - - 2.035e-216 684.0
REGS2_k127_4128104_10 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000006211 216.0
REGS2_k127_4128104_11 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000005829 190.0
REGS2_k127_4128104_12 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000004431 203.0
REGS2_k127_4128104_13 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000005734 199.0
REGS2_k127_4128104_14 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000931 176.0
REGS2_k127_4128104_15 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000002465 170.0
REGS2_k127_4128104_16 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000000000000000005075 174.0
REGS2_k127_4128104_17 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000001669 154.0
REGS2_k127_4128104_18 type II secretion system protein G K02456 - - 0.00000000000000000000000000000006804 132.0
REGS2_k127_4128104_19 RNA polymerase sigma factor K03088 - - 0.0000000000000000000004509 109.0
REGS2_k127_4128104_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 467.0
REGS2_k127_4128104_20 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000002173 92.0
REGS2_k127_4128104_21 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000004056 99.0
REGS2_k127_4128104_23 PFAM Fimbrial assembly family protein K02663 - - 0.00000000003379 71.0
REGS2_k127_4128104_24 Pilus assembly protein K02662 - - 0.0000000001904 72.0
REGS2_k127_4128104_25 general secretion pathway protein K02456,K02650 - - 0.0000000003058 72.0
REGS2_k127_4128104_27 general secretion pathway protein D K02453 - - 0.00006289 53.0
REGS2_k127_4128104_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 347.0
REGS2_k127_4128104_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
REGS2_k127_4128104_5 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 300.0
REGS2_k127_4128104_6 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003381 308.0
REGS2_k127_4128104_7 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004996 298.0
REGS2_k127_4128104_8 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001148 267.0
REGS2_k127_4128104_9 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000001724 252.0
REGS2_k127_4147367_0 SPTR Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 337.0
REGS2_k127_4147367_1 PFAM Aldo keto reductase family - - - 0.0000906 49.0
REGS2_k127_4164921_0 Cytochrome c - - - 4.424e-204 644.0
REGS2_k127_4164921_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 334.0
REGS2_k127_4164921_10 Protein of unknown function (DUF2911) - - - 0.000000000000000005822 93.0
REGS2_k127_4164921_11 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000007539 83.0
REGS2_k127_4164921_12 SMART metal-dependent phosphohydrolase, HD - - - 0.00000000000353 78.0
REGS2_k127_4164921_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 308.0
REGS2_k127_4164921_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003631 267.0
REGS2_k127_4164921_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000002958 214.0
REGS2_k127_4164921_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000001261 188.0
REGS2_k127_4164921_6 EVE domain - - - 0.00000000000000000000000000000000000000000002647 166.0
REGS2_k127_4164921_7 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000003461 134.0
REGS2_k127_4164921_9 TM2 domain - - - 0.0000000000000000000005279 105.0
REGS2_k127_4237778_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 610.0
REGS2_k127_4237778_1 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 511.0
REGS2_k127_4237778_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000001572 167.0
REGS2_k127_4237778_3 ATP hydrolysis coupled proton transport K02123 - - 0.0000000000000000000000002458 109.0
REGS2_k127_4237778_4 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000009109 93.0
REGS2_k127_4237778_5 ATPase activity, coupled to transmembrane movement of substances K02120 - - 0.00000000001606 76.0
REGS2_k127_4337194_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1342.0
REGS2_k127_4337194_1 peptidase K07386 - - 1.554e-256 810.0
REGS2_k127_4337194_10 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 348.0
REGS2_k127_4337194_11 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 342.0
REGS2_k127_4337194_12 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 313.0
REGS2_k127_4337194_13 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002706 266.0
REGS2_k127_4337194_14 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000001431 224.0
REGS2_k127_4337194_15 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000002381 218.0
REGS2_k127_4337194_16 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000000000006662 170.0
REGS2_k127_4337194_17 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000001162 168.0
REGS2_k127_4337194_18 DinB family - - - 0.0000000000000000000000000000000000000000008238 163.0
REGS2_k127_4337194_19 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000003289 163.0
REGS2_k127_4337194_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.261e-251 786.0
REGS2_k127_4337194_20 DinB family - - - 0.00000000000000000000000000000000000001693 150.0
REGS2_k127_4337194_21 - - - - 0.0000000000000000000000000000000000001956 149.0
REGS2_k127_4337194_22 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000224 134.0
REGS2_k127_4337194_23 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002571 139.0
REGS2_k127_4337194_24 Beta/gamma crystallins - - - 0.0000000000000000000000000000001486 138.0
REGS2_k127_4337194_25 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000003068 125.0
REGS2_k127_4337194_26 YCII-related domain - - - 0.000000000000000000000000001711 115.0
REGS2_k127_4337194_27 - - - - 0.00000000000000000000002537 112.0
REGS2_k127_4337194_28 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000000003538 104.0
REGS2_k127_4337194_29 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000009005 66.0
REGS2_k127_4337194_3 cellulose binding - - - 6.183e-220 716.0
REGS2_k127_4337194_30 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000003144 63.0
REGS2_k127_4337194_31 Baseplate J-like protein - - - 0.0000000006022 70.0
REGS2_k127_4337194_32 - - - - 0.000000000805 70.0
REGS2_k127_4337194_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 5.021e-213 673.0
REGS2_k127_4337194_5 Peptidase m28 - - - 5.145e-208 672.0
REGS2_k127_4337194_6 serine threonine protein kinase K12132 - 2.7.11.1 4.981e-201 657.0
REGS2_k127_4337194_7 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 598.0
REGS2_k127_4337194_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 435.0
REGS2_k127_4337194_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 416.0
REGS2_k127_4383758_0 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 571.0
REGS2_k127_4383758_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
REGS2_k127_4383758_2 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 303.0
REGS2_k127_4383758_3 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000001638 182.0
REGS2_k127_4383758_4 cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000002389 144.0
REGS2_k127_4383758_5 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000007442 141.0
REGS2_k127_4383758_6 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000231 70.0
REGS2_k127_4384235_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1297.0
REGS2_k127_4384235_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 5.64e-207 663.0
REGS2_k127_4384235_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 344.0
REGS2_k127_4384235_11 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 347.0
REGS2_k127_4384235_12 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 322.0
REGS2_k127_4384235_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000449 209.0
REGS2_k127_4384235_14 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000178 216.0
REGS2_k127_4384235_15 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000001861 204.0
REGS2_k127_4384235_16 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000005048 188.0
REGS2_k127_4384235_17 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000003168 179.0
REGS2_k127_4384235_18 IstB-like ATP binding protein K02315,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000003134 186.0
REGS2_k127_4384235_19 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.000000000000000000000000000000000001542 148.0
REGS2_k127_4384235_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 603.0
REGS2_k127_4384235_20 - - - - 0.00000000000000000000000000009634 122.0
REGS2_k127_4384235_21 Sigma-70 region 2 K03088 - - 0.00000000000000000000001876 108.0
REGS2_k127_4384235_22 PFAM Peptidase M23 - - - 0.00000000000000003655 97.0
REGS2_k127_4384235_23 - - - - 0.0000000000004767 79.0
REGS2_k127_4384235_24 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000004079 75.0
REGS2_k127_4384235_25 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000004459 72.0
REGS2_k127_4384235_26 Wd-40 repeat - - - 0.0000000000382 71.0
REGS2_k127_4384235_27 O-Antigen ligase - - - 0.00000001328 68.0
REGS2_k127_4384235_28 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K17414 - - 0.0000001353 64.0
REGS2_k127_4384235_3 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 602.0
REGS2_k127_4384235_30 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0002003 45.0
REGS2_k127_4384235_31 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0002651 49.0
REGS2_k127_4384235_32 Putative zinc-finger - - - 0.0006734 51.0
REGS2_k127_4384235_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 585.0
REGS2_k127_4384235_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 498.0
REGS2_k127_4384235_6 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 447.0
REGS2_k127_4384235_7 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 408.0
REGS2_k127_4384235_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 368.0
REGS2_k127_4384235_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 376.0
REGS2_k127_4395719_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.875e-284 899.0
REGS2_k127_4395719_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.793e-274 865.0
REGS2_k127_4395719_10 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 310.0
REGS2_k127_4395719_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 315.0
REGS2_k127_4395719_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 292.0
REGS2_k127_4395719_13 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003478 279.0
REGS2_k127_4395719_14 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007121 286.0
REGS2_k127_4395719_15 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001286 252.0
REGS2_k127_4395719_16 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000001966 243.0
REGS2_k127_4395719_17 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000003978 232.0
REGS2_k127_4395719_18 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000005142 222.0
REGS2_k127_4395719_19 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000001925 202.0
REGS2_k127_4395719_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.289e-229 720.0
REGS2_k127_4395719_20 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000001417 200.0
REGS2_k127_4395719_21 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000002532 190.0
REGS2_k127_4395719_22 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000005986 191.0
REGS2_k127_4395719_23 Histidine kinase - - - 0.000000000000000000000000000000000000000000005721 183.0
REGS2_k127_4395719_24 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000002998 144.0
REGS2_k127_4395719_25 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000006961 138.0
REGS2_k127_4395719_26 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000002634 136.0
REGS2_k127_4395719_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000007406 100.0
REGS2_k127_4395719_28 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000002948 101.0
REGS2_k127_4395719_29 Putative single-stranded nucleic acids-binding domain K06346 - - 0.0000000000000000000258 100.0
REGS2_k127_4395719_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.088e-226 726.0
REGS2_k127_4395719_30 Polymer-forming cytoskeletal - - - 0.00000000000000000004755 98.0
REGS2_k127_4395719_31 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000002202 94.0
REGS2_k127_4395719_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000001532 88.0
REGS2_k127_4395719_33 Ribosomal protein L34 K02914 - - 0.0000000000000266 73.0
REGS2_k127_4395719_34 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000005241 76.0
REGS2_k127_4395719_35 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000009096 65.0
REGS2_k127_4395719_36 arylamine N-acetyltransferase activity - - - 0.00000001182 67.0
REGS2_k127_4395719_37 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000001857 63.0
REGS2_k127_4395719_38 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000008343 59.0
REGS2_k127_4395719_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 602.0
REGS2_k127_4395719_5 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 547.0
REGS2_k127_4395719_6 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 512.0
REGS2_k127_4395719_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 442.0
REGS2_k127_4395719_8 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 411.0
REGS2_k127_4395719_9 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
REGS2_k127_4399405_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 485.0
REGS2_k127_4399405_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 296.0
REGS2_k127_4399405_2 iron ion homeostasis K02012 - - 0.00000000000007158 74.0
REGS2_k127_4399405_3 - - - - 0.000000000007848 70.0
REGS2_k127_4399405_4 - - - - 0.000000003048 65.0
REGS2_k127_4409474_0 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 423.0
REGS2_k127_4409474_1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
REGS2_k127_4409474_10 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000008199 187.0
REGS2_k127_4409474_11 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000009232 153.0
REGS2_k127_4409474_12 Putative porin - - - 0.0000000169 66.0
REGS2_k127_4409474_13 - - - - 0.0004521 53.0
REGS2_k127_4409474_2 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 303.0
REGS2_k127_4409474_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 300.0
REGS2_k127_4409474_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002064 268.0
REGS2_k127_4409474_6 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000001369 229.0
REGS2_k127_4409474_7 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000005275 235.0
REGS2_k127_4409474_8 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000623 215.0
REGS2_k127_4409474_9 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000522 194.0
REGS2_k127_4461263_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1329.0
REGS2_k127_4461263_1 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 557.0
REGS2_k127_4461263_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
REGS2_k127_4461263_11 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000007135 195.0
REGS2_k127_4461263_12 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000002106 146.0
REGS2_k127_4461263_13 Uroporphyrinogen III synthase HEM4 K01719,K13542 - 2.1.1.107,4.2.1.75 0.00000000006822 75.0
REGS2_k127_4461263_14 - - - - 0.00000009216 58.0
REGS2_k127_4461263_2 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 481.0
REGS2_k127_4461263_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 432.0
REGS2_k127_4461263_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 447.0
REGS2_k127_4461263_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 445.0
REGS2_k127_4461263_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 329.0
REGS2_k127_4461263_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 323.0
REGS2_k127_4461263_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 301.0
REGS2_k127_4461263_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001697 276.0
REGS2_k127_4609769_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 580.0
REGS2_k127_4609769_1 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 490.0
REGS2_k127_4609769_10 ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006508,GO:0006605,GO:0006625,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0016043,GO:0016485,GO:0019538,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043574,GO:0044238,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564 3.4.21.53 0.00008538 55.0
REGS2_k127_4609769_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008719 281.0
REGS2_k127_4609769_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000006597 264.0
REGS2_k127_4609769_5 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005571 246.0
REGS2_k127_4609769_6 membrane - - - 0.000000000000000000000000000000000006774 152.0
REGS2_k127_4609769_7 DinB superfamily K07552 - - 0.0000000000000000000000000000000004276 137.0
REGS2_k127_4609769_8 HD domain - - - 0.000000000000000000001866 100.0
REGS2_k127_4609769_9 - - - - 0.00000000001422 70.0
REGS2_k127_4611877_0 Uncharacterized protein family (UPF0051) K09014 - - 3.057e-266 824.0
REGS2_k127_4611877_1 Phosphoesterase family - - - 2.644e-209 688.0
REGS2_k127_4611877_10 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 361.0
REGS2_k127_4611877_11 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001835 309.0
REGS2_k127_4611877_12 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008111 275.0
REGS2_k127_4611877_13 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001025 263.0
REGS2_k127_4611877_14 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000000000000001234 196.0
REGS2_k127_4611877_15 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000002814 198.0
REGS2_k127_4611877_16 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000004469 183.0
REGS2_k127_4611877_17 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000774 165.0
REGS2_k127_4611877_18 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000001768 148.0
REGS2_k127_4611877_19 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000001312 139.0
REGS2_k127_4611877_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 578.0
REGS2_k127_4611877_20 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000001287 132.0
REGS2_k127_4611877_21 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0000000000000000000000000000003211 126.0
REGS2_k127_4611877_22 - - - - 0.00000000000000000001275 94.0
REGS2_k127_4611877_23 Late embryogenesis abundant protein - - - 0.000000000000000001897 92.0
REGS2_k127_4611877_24 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000004303 91.0
REGS2_k127_4611877_25 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000001166 74.0
REGS2_k127_4611877_26 PFAM PKD domain containing protein - - - 0.00000001171 69.0
REGS2_k127_4611877_3 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 485.0
REGS2_k127_4611877_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 428.0
REGS2_k127_4611877_5 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 385.0
REGS2_k127_4611877_6 4-hydroxyproline epimerase activity K01777,K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 376.0
REGS2_k127_4611877_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 377.0
REGS2_k127_4611877_8 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 383.0
REGS2_k127_4611877_9 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 361.0
REGS2_k127_4636561_0 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 314.0
REGS2_k127_4636561_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000003195 234.0
REGS2_k127_4657593_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 543.0
REGS2_k127_4657593_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 378.0
REGS2_k127_4657593_10 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000009252 51.0
REGS2_k127_4657593_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000000000000000000000000000000000000001867 239.0
REGS2_k127_4657593_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000002631 222.0
REGS2_k127_4657593_4 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000001211 163.0
REGS2_k127_4657593_5 TIR domain - - - 0.0000000000000000000000000000000000000000052 168.0
REGS2_k127_4657593_6 PIN domain - - - 0.00000000000000000000000000000000000000002644 159.0
REGS2_k127_4657593_7 pfam nudix - - - 0.0000000000000000000000000000005983 129.0
REGS2_k127_4657593_8 - - - - 0.00000000000000000000818 94.0
REGS2_k127_4657593_9 recA bacterial DNA recombination protein - - - 0.00000001143 66.0
REGS2_k127_4721638_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1246.0
REGS2_k127_4721638_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.689e-314 986.0
REGS2_k127_4721638_10 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 637.0
REGS2_k127_4721638_11 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 612.0
REGS2_k127_4721638_12 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 610.0
REGS2_k127_4721638_13 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 573.0
REGS2_k127_4721638_14 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 533.0
REGS2_k127_4721638_15 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 497.0
REGS2_k127_4721638_16 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 519.0
REGS2_k127_4721638_17 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 472.0
REGS2_k127_4721638_18 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 430.0
REGS2_k127_4721638_19 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 432.0
REGS2_k127_4721638_2 Dehydrogenase E1 component K11381,K21416 - 1.2.4.4 2.07e-274 885.0
REGS2_k127_4721638_20 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 420.0
REGS2_k127_4721638_21 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 412.0
REGS2_k127_4721638_22 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 401.0
REGS2_k127_4721638_23 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 387.0
REGS2_k127_4721638_24 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 376.0
REGS2_k127_4721638_25 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 391.0
REGS2_k127_4721638_26 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 353.0
REGS2_k127_4721638_27 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 322.0
REGS2_k127_4721638_28 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 295.0
REGS2_k127_4721638_29 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 312.0
REGS2_k127_4721638_3 Succinyl-CoA ligase like flavodoxin domain - - - 6.983e-274 878.0
REGS2_k127_4721638_30 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001013 312.0
REGS2_k127_4721638_31 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005404 283.0
REGS2_k127_4721638_32 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003296 265.0
REGS2_k127_4721638_33 Erythromycin esterase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 257.0
REGS2_k127_4721638_34 PFAM Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000008223 244.0
REGS2_k127_4721638_35 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001374 260.0
REGS2_k127_4721638_36 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000004405 223.0
REGS2_k127_4721638_37 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000112 217.0
REGS2_k127_4721638_38 PFAM Glycosyl transferase family 2 K14597 - - 0.00000000000000000000000000000000000000000000000000000002815 213.0
REGS2_k127_4721638_39 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000789 200.0
REGS2_k127_4721638_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.964e-271 845.0
REGS2_k127_4721638_40 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000277 173.0
REGS2_k127_4721638_41 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000003002 168.0
REGS2_k127_4721638_42 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000000000000003242 162.0
REGS2_k127_4721638_43 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000004148 152.0
REGS2_k127_4721638_44 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000005009 154.0
REGS2_k127_4721638_45 hyperosmotic response - - - 0.00000000000000000000000000000000009524 138.0
REGS2_k127_4721638_46 ECF sigma factor K03088 - - 0.000000000000000000000000000001773 128.0
REGS2_k127_4721638_47 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.0000000000000000000000000000818 122.0
REGS2_k127_4721638_48 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000002809 134.0
REGS2_k127_4721638_49 GYD domain - - - 0.000000000000000000000000001309 120.0
REGS2_k127_4721638_5 phosphatase activity - - - 4.828e-254 797.0
REGS2_k127_4721638_50 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000004587 112.0
REGS2_k127_4721638_51 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000001142 120.0
REGS2_k127_4721638_52 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000004741 119.0
REGS2_k127_4721638_53 - - - - 0.00000000000000000000001163 111.0
REGS2_k127_4721638_54 Universal stress protein - - - 0.0000000000000000000000508 104.0
REGS2_k127_4721638_55 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000005821 104.0
REGS2_k127_4721638_56 PFAM CBS domain containing protein K07168 - - 0.000000000000000000001566 108.0
REGS2_k127_4721638_57 Protein of unknown function (DUF962) - - - 0.00000000000000000002167 101.0
REGS2_k127_4721638_58 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000008246 98.0
REGS2_k127_4721638_59 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000005735 87.0
REGS2_k127_4721638_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.147e-239 758.0
REGS2_k127_4721638_60 ACT domain K04767 - - 0.0000000000000007239 86.0
REGS2_k127_4721638_61 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000001179 71.0
REGS2_k127_4721638_62 Heavy-metal resistance - - - 0.0000000000001588 81.0
REGS2_k127_4721638_63 Phosphopantetheine attachment site - - - 0.0000000000003339 82.0
REGS2_k127_4721638_64 Bacterial PH domain - - - 0.00000000001071 73.0
REGS2_k127_4721638_65 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000001928 71.0
REGS2_k127_4721638_66 Family of unknown function (DUF5335) - - - 0.00000002488 61.0
REGS2_k127_4721638_67 Dienelactone hydrolase K07100 - - 0.0000003604 57.0
REGS2_k127_4721638_68 Family of unknown function (DUF5335) - - - 0.000006774 55.0
REGS2_k127_4721638_69 mRNA catabolic process K06950 - - 0.00001639 54.0
REGS2_k127_4721638_7 DNA polymerase beta thumb K02347 - - 7.35e-232 732.0
REGS2_k127_4721638_70 Iron-sulphur cluster biosynthesis K13628,K15724 - - 0.00002748 51.0
REGS2_k127_4721638_71 Tetratricopeptide repeat - - - 0.00004899 53.0
REGS2_k127_4721638_72 general secretion pathway protein K02456,K02457,K10930 - - 0.000164 53.0
REGS2_k127_4721638_8 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.239e-222 714.0
REGS2_k127_4721638_9 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 2.613e-197 625.0
REGS2_k127_4737291_0 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 527.0
REGS2_k127_4737291_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 438.0
REGS2_k127_4737291_2 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 414.0
REGS2_k127_4737291_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 293.0
REGS2_k127_4737291_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001171 278.0
REGS2_k127_4737291_5 PFAM FecR protein - - - 0.0000000000000000000000002683 121.0
REGS2_k127_4737291_6 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000006747 98.0
REGS2_k127_4737291_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000004379 68.0
REGS2_k127_4747697_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.982e-243 777.0
REGS2_k127_4747697_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 601.0
REGS2_k127_4747697_10 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000003314 115.0
REGS2_k127_4747697_11 Sigma-70, region 4 K03088 - - 0.000000000000000000000000008395 122.0
REGS2_k127_4747697_12 - - - - 0.00000000000000000000000008313 120.0
REGS2_k127_4747697_13 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000005285 92.0
REGS2_k127_4747697_14 Salt-induced outer membrane protein K07283 - - 0.00000000000000001046 94.0
REGS2_k127_4747697_15 Thioesterase-like superfamily K07107 - - 0.0000000000000003851 83.0
REGS2_k127_4747697_16 Cupin 2 conserved barrel domain protein - - - 0.00000000000005184 76.0
REGS2_k127_4747697_2 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 337.0
REGS2_k127_4747697_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004858 282.0
REGS2_k127_4747697_4 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004193 263.0
REGS2_k127_4747697_5 Chlorophyllase - - - 0.000000000000000000000000000000000000000000000002313 199.0
REGS2_k127_4747697_6 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000005524 160.0
REGS2_k127_4747697_7 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000001041 146.0
REGS2_k127_4747697_8 - - - - 0.000000000000000000000000000002261 135.0
REGS2_k127_4747697_9 Peptidase family M54 K06974 - - 0.000000000000000000000000000003081 137.0
REGS2_k127_4847767_0 ABC transporter K06020 - 3.6.3.25 3.12e-255 805.0
REGS2_k127_4847767_1 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 276.0
REGS2_k127_4847767_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000004106 186.0
REGS2_k127_4847767_3 Transglycosylase associated protein - - - 0.000000000000000000000001576 113.0
REGS2_k127_4847767_4 Protein of unknown function (DUF983) - - - 0.0000000000000006601 84.0
REGS2_k127_4863988_0 B12 binding domain - - - 3.434e-227 712.0
REGS2_k127_4863988_1 IgA Peptidase M64 - - - 1.144e-224 704.0
REGS2_k127_4863988_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 483.0
REGS2_k127_4863988_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003419 256.0
REGS2_k127_4863988_4 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000107 174.0
REGS2_k127_4863988_5 Peptidase, M16 family protein K07263,K07623 - - 0.0000000000000000000000000002293 132.0
REGS2_k127_4863988_6 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000001004 126.0
REGS2_k127_4863988_7 Adenylate cyclase - - - 0.0000000000002602 79.0
REGS2_k127_4863988_8 FHA domain containing protein - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000003176 73.0
REGS2_k127_4996143_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 7.676e-278 867.0
REGS2_k127_4996143_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 613.0
REGS2_k127_4996143_2 RNB K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 592.0
REGS2_k127_4996143_3 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 370.0
REGS2_k127_4996143_4 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 353.0
REGS2_k127_4996143_5 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000008606 223.0
REGS2_k127_4996143_6 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000002546 178.0
REGS2_k127_5039731_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 531.0
REGS2_k127_5039731_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000002445 150.0
REGS2_k127_5039731_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000005496 121.0
REGS2_k127_5039731_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000001485 93.0
REGS2_k127_5160785_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 3.91e-314 981.0
REGS2_k127_5182652_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 318.0
REGS2_k127_5182652_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002889 235.0
REGS2_k127_5182652_10 glycosyl transferase K20444 - - 0.0000000000000000003133 104.0
REGS2_k127_5182652_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000002775 91.0
REGS2_k127_5182652_12 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000004142 90.0
REGS2_k127_5182652_13 PFAM PEGA domain - - - 0.000003895 59.0
REGS2_k127_5182652_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000002617 211.0
REGS2_k127_5182652_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000002841 190.0
REGS2_k127_5182652_4 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000004977 190.0
REGS2_k127_5182652_5 transferase activity, transferring glycosyl groups K13659 - 2.4.1.264 0.000000000000000000000000000000000000000000003066 189.0
REGS2_k127_5182652_6 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000001949 167.0
REGS2_k127_5182652_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000004519 153.0
REGS2_k127_5182652_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000936 131.0
REGS2_k127_5182652_9 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000007111 107.0
REGS2_k127_5183595_0 PFAM BNR Asp-box repeat - - - 0.0 1129.0
REGS2_k127_5183595_1 Flotillin K07192 - - 9.864e-217 682.0
REGS2_k127_5183595_10 Belongs to the UPF0145 family - - - 0.000000000000006875 79.0
REGS2_k127_5183595_2 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000002099 232.0
REGS2_k127_5183595_3 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
REGS2_k127_5183595_4 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000001043 222.0
REGS2_k127_5183595_5 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000000000000000000000000000000001108 198.0
REGS2_k127_5183595_6 Domain of unknown function (DUF305) K08995 - - 0.00000000000000000000000000000000000000000001917 177.0
REGS2_k127_5183595_7 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000000000071 147.0
REGS2_k127_5183595_8 DoxX K15977 - - 0.00000000000000000000000000000000018 137.0
REGS2_k127_5183595_9 - - - - 0.0000000000000000000000000006425 118.0
REGS2_k127_5239385_0 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001826 284.0
REGS2_k127_5239385_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000002831 116.0
REGS2_k127_5239385_2 Dehydrogenase - - - 0.00000000000000000000004255 105.0
REGS2_k127_5239385_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000001565 93.0
REGS2_k127_5239385_4 beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000001718 75.0
REGS2_k127_5239385_5 Belongs to the universal stress protein A family - - - 0.000001329 60.0
REGS2_k127_5239385_6 - - - - 0.00002222 56.0
REGS2_k127_52513_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.243e-283 889.0
REGS2_k127_52513_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 584.0
REGS2_k127_52513_10 - - - - 0.00000000000000000000000000000000000002335 153.0
REGS2_k127_52513_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000002916 115.0
REGS2_k127_52513_12 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000005476 106.0
REGS2_k127_52513_13 esterase - - - 0.000000000000000000000001401 120.0
REGS2_k127_52513_14 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000000000000000001896 100.0
REGS2_k127_52513_15 Iron-sulfur cluster-binding domain - - - 0.00000000000008839 84.0
REGS2_k127_52513_16 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000002958 74.0
REGS2_k127_52513_17 - - - - 0.00000000001174 71.0
REGS2_k127_52513_18 RecQ zinc-binding K03654 - 3.6.4.12 0.00000001356 61.0
REGS2_k127_52513_19 Natural resistance-associated macrophage protein - - - 0.000003484 53.0
REGS2_k127_52513_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 434.0
REGS2_k127_52513_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
REGS2_k127_52513_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002082 253.0
REGS2_k127_52513_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002158 234.0
REGS2_k127_52513_6 KR domain K07535 - - 0.000000000000000000000000000000000000000000000000005676 190.0
REGS2_k127_52513_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000002488 196.0
REGS2_k127_52513_8 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000000000678 184.0
REGS2_k127_52513_9 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000005949 158.0
REGS2_k127_5262919_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 390.0
REGS2_k127_5262919_1 TonB-dependent receptor - - - 0.00007211 49.0
REGS2_k127_5288383_0 Involved in the tonB-independent uptake of proteins - - - 1.213e-207 674.0
REGS2_k127_5288383_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 454.0
REGS2_k127_5288383_10 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000545 218.0
REGS2_k127_5288383_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000001036 160.0
REGS2_k127_5288383_12 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000001259 145.0
REGS2_k127_5288383_13 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000005751 142.0
REGS2_k127_5288383_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000143 110.0
REGS2_k127_5288383_15 DSBA-like thioredoxin domain - - - 0.000000000000000000001775 107.0
REGS2_k127_5288383_16 membrane - GO:0005575,GO:0016020 - 0.00000000000000000167 101.0
REGS2_k127_5288383_17 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000002482 100.0
REGS2_k127_5288383_18 Belongs to the 'phage' integrase family - - - 0.000000000000006868 78.0
REGS2_k127_5288383_19 Peptidase M56 - - - 0.0000000000001552 82.0
REGS2_k127_5288383_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 452.0
REGS2_k127_5288383_20 bacteriochlorophyll K04040 - 2.5.1.133,2.5.1.62 0.000000000005006 79.0
REGS2_k127_5288383_21 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000006714 69.0
REGS2_k127_5288383_22 Thioredoxin - - - 0.000002209 61.0
REGS2_k127_5288383_24 Phosphoserine phosphatase - - - 0.00004858 57.0
REGS2_k127_5288383_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 400.0
REGS2_k127_5288383_4 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
REGS2_k127_5288383_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 333.0
REGS2_k127_5288383_6 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 316.0
REGS2_k127_5288383_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000002391 224.0
REGS2_k127_5288383_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000008492 234.0
REGS2_k127_5288383_9 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000903 219.0
REGS2_k127_5299067_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 507.0
REGS2_k127_5299067_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 459.0
REGS2_k127_5299067_10 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000006862 231.0
REGS2_k127_5299067_11 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000004043 216.0
REGS2_k127_5299067_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000148 207.0
REGS2_k127_5299067_13 GAF domain - - - 0.0000000000000000000000000000000000000000000000003597 190.0
REGS2_k127_5299067_14 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000001204 193.0
REGS2_k127_5299067_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000001921 147.0
REGS2_k127_5299067_16 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.00000000000000000000000000000001134 139.0
REGS2_k127_5299067_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000001261 108.0
REGS2_k127_5299067_18 Mediates influx of magnesium ions K03284 - - 0.00000000000000000007761 104.0
REGS2_k127_5299067_19 hydrolase, family 1 K05350 - 3.2.1.21 0.0000002247 53.0
REGS2_k127_5299067_2 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 417.0
REGS2_k127_5299067_20 endoglucanase-related protein, glucosyl hydrolase family 9 protein K01238 - - - 0.000002572 58.0
REGS2_k127_5299067_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 382.0
REGS2_k127_5299067_4 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 364.0
REGS2_k127_5299067_5 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 358.0
REGS2_k127_5299067_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001239 280.0
REGS2_k127_5299067_7 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000001129 254.0
REGS2_k127_5299067_8 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002809 252.0
REGS2_k127_5299067_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000004099 233.0
REGS2_k127_536496_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 2.197e-223 701.0
REGS2_k127_536496_1 cluster binding protein K18929 - - 4.615e-204 657.0
REGS2_k127_536496_10 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 301.0
REGS2_k127_536496_11 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005677 262.0
REGS2_k127_536496_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
REGS2_k127_536496_13 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000004414 248.0
REGS2_k127_536496_14 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000002101 240.0
REGS2_k127_536496_15 PFAM Hly-III family protein K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
REGS2_k127_536496_16 NAD(P)H quinone oxidoreductase, PIG3 family K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000004239 247.0
REGS2_k127_536496_17 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000001673 197.0
REGS2_k127_536496_18 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000005414 166.0
REGS2_k127_536496_19 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000000005869 168.0
REGS2_k127_536496_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 454.0
REGS2_k127_536496_20 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000002067 144.0
REGS2_k127_536496_21 SNARE associated Golgi protein - - - 0.0000000000000000000000000000001422 138.0
REGS2_k127_536496_22 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000003946 132.0
REGS2_k127_536496_23 COG1145 Ferredoxin - - - 0.000000000000000000000000002261 113.0
REGS2_k127_536496_24 - - - - 0.000000000000000000000000004723 111.0
REGS2_k127_536496_25 TonB dependent receptor - - - 0.0000000000000000000000001525 124.0
REGS2_k127_536496_27 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.0000000000000000000000009251 109.0
REGS2_k127_536496_29 Peptidase M56 - - - 0.000000000000009922 86.0
REGS2_k127_536496_3 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 421.0
REGS2_k127_536496_30 GAF domain K08968 - 1.8.4.14 0.00000000000005654 76.0
REGS2_k127_536496_33 Tetratricopeptide repeat - - - 0.00000000007294 74.0
REGS2_k127_536496_34 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000006707 69.0
REGS2_k127_536496_35 Thioredoxin-like - - - 0.0000006191 61.0
REGS2_k127_536496_4 Aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 427.0
REGS2_k127_536496_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 356.0
REGS2_k127_536496_6 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 351.0
REGS2_k127_536496_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 342.0
REGS2_k127_536496_8 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 334.0
REGS2_k127_536496_9 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 316.0
REGS2_k127_5442970_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 575.0
REGS2_k127_5442970_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008151 254.0
REGS2_k127_5442970_10 Cytochrome c K00406,K08906 - - 0.000001268 55.0
REGS2_k127_5442970_11 Domain of unknown function (DUF4198) - - - 0.0007783 46.0
REGS2_k127_5442970_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005374 239.0
REGS2_k127_5442970_3 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000002279 226.0
REGS2_k127_5442970_4 PFAM Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000001675 179.0
REGS2_k127_5442970_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000003633 177.0
REGS2_k127_5442970_6 Tricorn protease homolog K03797,K08676 - 3.4.21.102 0.00000000000000003088 96.0
REGS2_k127_5442970_7 Fibronectin type III domain protein - - - 0.0000000000000271 85.0
REGS2_k127_5442970_8 Domain of unknown function (DUF4198) - - - 0.000000006279 59.0
REGS2_k127_5442970_9 Protein of unknown function (DUF1015) - - - 0.0000001023 62.0
REGS2_k127_550552_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
REGS2_k127_550552_1 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 357.0
REGS2_k127_550552_10 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.00000000000000000000000000000137 131.0
REGS2_k127_550552_11 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000001025 102.0
REGS2_k127_550552_12 IMG reference gene - - - 0.0000000000002924 81.0
REGS2_k127_550552_13 - - - - 0.000009931 57.0
REGS2_k127_550552_14 - - - - 0.00005975 54.0
REGS2_k127_550552_15 - - - - 0.000725 52.0
REGS2_k127_550552_2 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 259.0
REGS2_k127_550552_3 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000004994 247.0
REGS2_k127_550552_4 TonB-dependent Receptor Plug K16092 - - 0.00000000000000000000000000000000000000000000000000000002017 221.0
REGS2_k127_550552_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000001185 195.0
REGS2_k127_550552_6 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000003367 184.0
REGS2_k127_550552_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000001051 163.0
REGS2_k127_550552_8 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000007471 153.0
REGS2_k127_550552_9 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000269 153.0
REGS2_k127_5510371_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 512.0
REGS2_k127_5510371_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 443.0
REGS2_k127_5510371_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 344.0
REGS2_k127_5510371_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 326.0
REGS2_k127_5510371_4 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001486 287.0
REGS2_k127_5510371_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000005641 246.0
REGS2_k127_5510371_6 Cell division protein FtsQ K03589 - - 0.00000001131 65.0
REGS2_k127_5557574_0 AAA ATPase domain - - - 0.0 1082.0
REGS2_k127_5557574_1 radical SAM domain protein - - - 1.846e-203 646.0
REGS2_k127_5557574_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 396.0
REGS2_k127_5557574_3 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 239.0
REGS2_k127_5557574_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000001196 207.0
REGS2_k127_5557574_5 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000001546 207.0
REGS2_k127_5557574_6 - - - - 0.000000000000000000000000000000000000000000000000001785 190.0
REGS2_k127_5557574_8 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000006993 138.0
REGS2_k127_5557574_9 Cytochrome c554 and c-prime - - - 0.00000000000000003446 94.0
REGS2_k127_5564790_0 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 448.0
REGS2_k127_5564790_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 339.0
REGS2_k127_5564790_2 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000002482 196.0
REGS2_k127_5564790_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000001636 188.0
REGS2_k127_5564790_4 - - - - 0.000000000000005975 79.0
REGS2_k127_5574280_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 519.0
REGS2_k127_5574280_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 490.0
REGS2_k127_5574280_10 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 341.0
REGS2_k127_5574280_11 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 333.0
REGS2_k127_5574280_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 322.0
REGS2_k127_5574280_13 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 329.0
REGS2_k127_5574280_14 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 308.0
REGS2_k127_5574280_15 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
REGS2_k127_5574280_16 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 299.0
REGS2_k127_5574280_17 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 317.0
REGS2_k127_5574280_18 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 295.0
REGS2_k127_5574280_19 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005438 298.0
REGS2_k127_5574280_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 428.0
REGS2_k127_5574280_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001327 268.0
REGS2_k127_5574280_21 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001581 264.0
REGS2_k127_5574280_22 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000009501 267.0
REGS2_k127_5574280_23 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005373 259.0
REGS2_k127_5574280_24 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002123 249.0
REGS2_k127_5574280_25 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000001729 237.0
REGS2_k127_5574280_26 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000007088 208.0
REGS2_k127_5574280_27 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000127 200.0
REGS2_k127_5574280_28 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000006997 203.0
REGS2_k127_5574280_29 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000001244 182.0
REGS2_k127_5574280_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 443.0
REGS2_k127_5574280_30 - K07018 - - 0.0000000000000000000000000000000000000000000001091 175.0
REGS2_k127_5574280_31 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000002038 166.0
REGS2_k127_5574280_32 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000004736 164.0
REGS2_k127_5574280_33 NUDIX domain - - - 0.00000000000000000000000000000000000006478 154.0
REGS2_k127_5574280_34 PAP2 superfamily - - - 0.0000000000000000000000000000000000001398 152.0
REGS2_k127_5574280_35 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000007355 139.0
REGS2_k127_5574280_36 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000163 135.0
REGS2_k127_5574280_37 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000003074 134.0
REGS2_k127_5574280_38 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000807 128.0
REGS2_k127_5574280_39 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000001147 101.0
REGS2_k127_5574280_4 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 423.0
REGS2_k127_5574280_40 thiolester hydrolase activity K17362 - - 0.0000000000000009818 83.0
REGS2_k127_5574280_41 YXWGXW repeat (2 copies) - - - 0.000000000000001858 79.0
REGS2_k127_5574280_42 Tetratricopeptide repeat - - - 0.0000006569 62.0
REGS2_k127_5574280_43 Sporulation related domain K03749 - - 0.000002361 58.0
REGS2_k127_5574280_5 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 388.0
REGS2_k127_5574280_6 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
REGS2_k127_5574280_7 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 383.0
REGS2_k127_5574280_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 377.0
REGS2_k127_5574280_9 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 374.0
REGS2_k127_5582117_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.584e-231 766.0
REGS2_k127_5582117_1 Alpha/beta hydrolase family - - - 7.117e-195 632.0
REGS2_k127_5582117_10 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 312.0
REGS2_k127_5582117_11 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 299.0
REGS2_k127_5582117_12 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005191 268.0
REGS2_k127_5582117_13 ATP-grasp domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000869 249.0
REGS2_k127_5582117_14 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002761 245.0
REGS2_k127_5582117_15 maltose O-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
REGS2_k127_5582117_16 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000002531 239.0
REGS2_k127_5582117_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000005863 227.0
REGS2_k127_5582117_18 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000002479 232.0
REGS2_k127_5582117_19 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000001448 206.0
REGS2_k127_5582117_2 PHP domain protein K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 539.0
REGS2_k127_5582117_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000002789 207.0
REGS2_k127_5582117_21 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356,K03503 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000009271 192.0
REGS2_k127_5582117_22 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000001338 205.0
REGS2_k127_5582117_23 metal-dependent phosphoesterases (PHP family) K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000001382 195.0
REGS2_k127_5582117_24 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000008962 196.0
REGS2_k127_5582117_25 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000482 182.0
REGS2_k127_5582117_26 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000007523 148.0
REGS2_k127_5582117_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000007271 159.0
REGS2_k127_5582117_28 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000001461 143.0
REGS2_k127_5582117_29 zinc ion binding K04477,K07053 - 3.1.3.97 0.00000000000000000000000000000000007011 143.0
REGS2_k127_5582117_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 507.0
REGS2_k127_5582117_31 PFAM regulatory protein TetR - - - 0.000005505 56.0
REGS2_k127_5582117_32 - - - - 0.000009893 50.0
REGS2_k127_5582117_33 Thioredoxin-like - - - 0.00001652 56.0
REGS2_k127_5582117_35 Sortase family K07284 - 3.4.22.70 0.00009233 54.0
REGS2_k127_5582117_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 474.0
REGS2_k127_5582117_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 403.0
REGS2_k127_5582117_6 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 393.0
REGS2_k127_5582117_7 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 374.0
REGS2_k127_5582117_8 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
REGS2_k127_5582117_9 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 336.0
REGS2_k127_5666076_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 604.0
REGS2_k127_5666076_1 nitrite reductase [NAD(P)H] activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 321.0
REGS2_k127_5666076_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002001 279.0
REGS2_k127_5666076_3 - - - - 0.00000000000000000000000000001946 123.0
REGS2_k127_5666076_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000002159 125.0
REGS2_k127_5666076_5 SnoaL-like domain - - - 0.00000000000000000000008493 109.0
REGS2_k127_5666076_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000008948 102.0
REGS2_k127_5692540_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.222e-314 976.0
REGS2_k127_5692540_1 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 289.0
REGS2_k127_5692540_10 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000001091 85.0
REGS2_k127_5692540_11 L,D-transpeptidase catalytic domain - - - 0.000000825 63.0
REGS2_k127_5692540_2 Peptidase M15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004187 272.0
REGS2_k127_5692540_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001217 256.0
REGS2_k127_5692540_4 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000029 232.0
REGS2_k127_5692540_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000001424 208.0
REGS2_k127_5692540_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000002675 194.0
REGS2_k127_5692540_7 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000001174 172.0
REGS2_k127_5692540_8 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000001213 125.0
REGS2_k127_5692540_9 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000001492 129.0
REGS2_k127_5782046_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 452.0
REGS2_k127_5782046_2 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000002492 113.0
REGS2_k127_5782046_3 Immunoglobulin - - - 0.00000000000000000006412 106.0
REGS2_k127_5782046_4 ACT domain - - - 0.000000000000000265 84.0
REGS2_k127_5782046_5 Bacterial protein of unknown function (DUF885) - - - 0.000000001123 62.0
REGS2_k127_5863894_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2494.0
REGS2_k127_5863894_1 Protein chain release factor B K15034 - - 0.00000000000000000000000000000006251 130.0
REGS2_k127_5863894_2 Putative adhesin - - - 0.0005438 51.0
REGS2_k127_5912486_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
REGS2_k127_5912486_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000001019 172.0
REGS2_k127_5912486_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000002699 170.0
REGS2_k127_5912486_3 Bacterial DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.0000000000000000000000001716 112.0
REGS2_k127_5912486_4 Multicopper K06324 - 1.16.3.3 0.00000001244 55.0
REGS2_k127_5912486_5 Belongs to the UPF0235 family K09131 - - 0.0000002214 57.0
REGS2_k127_6048415_0 AMP-binding enzyme K01897 - 6.2.1.3 4.156e-290 903.0
REGS2_k127_6048415_1 Periplasmic binding protein K01999 - - 8.504e-202 638.0
REGS2_k127_6048415_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 389.0
REGS2_k127_6048415_11 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 387.0
REGS2_k127_6048415_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 361.0
REGS2_k127_6048415_13 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 340.0
REGS2_k127_6048415_14 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009245 293.0
REGS2_k127_6048415_15 Transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
REGS2_k127_6048415_16 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000002079 239.0
REGS2_k127_6048415_17 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000263 239.0
REGS2_k127_6048415_18 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000001573 225.0
REGS2_k127_6048415_19 transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000142 222.0
REGS2_k127_6048415_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 575.0
REGS2_k127_6048415_20 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000002293 216.0
REGS2_k127_6048415_21 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000008891 196.0
REGS2_k127_6048415_22 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000009082 196.0
REGS2_k127_6048415_23 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000006799 182.0
REGS2_k127_6048415_24 TPM domain - - - 0.000000000000000000000000000000000000001201 151.0
REGS2_k127_6048415_25 Hit family K02503 - - 0.00000000000000000000000000000000000002353 146.0
REGS2_k127_6048415_26 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000003031 142.0
REGS2_k127_6048415_27 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000003143 133.0
REGS2_k127_6048415_28 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000412 118.0
REGS2_k127_6048415_29 Binds the 23S rRNA K02909 - - 0.00000000000000000000000006021 111.0
REGS2_k127_6048415_3 coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 502.0
REGS2_k127_6048415_30 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.000000000000000000001548 100.0
REGS2_k127_6048415_31 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000001741 92.0
REGS2_k127_6048415_32 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000004491 96.0
REGS2_k127_6048415_33 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000001118 85.0
REGS2_k127_6048415_34 DNA polymerase III (delta' subunit) K02340 - 2.7.7.7 0.0000003243 63.0
REGS2_k127_6048415_35 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00055 46.0
REGS2_k127_6048415_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 489.0
REGS2_k127_6048415_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
REGS2_k127_6048415_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 433.0
REGS2_k127_6048415_7 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 399.0
REGS2_k127_6048415_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 398.0
REGS2_k127_6048415_9 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 402.0
REGS2_k127_6054743_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 438.0
REGS2_k127_6054743_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 358.0
REGS2_k127_6140878_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 329.0
REGS2_k127_6140878_1 oxidoreductase activity - - - 0.000000000000000000000000002624 128.0
REGS2_k127_6140878_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000004345 124.0
REGS2_k127_6140878_3 Glutathione peroxidase - - - 0.000000000000000000000008127 109.0
REGS2_k127_6140878_4 Tetratricopeptide repeat - - - 0.00000000000000000000001023 115.0
REGS2_k127_6140878_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000009591 98.0
REGS2_k127_6140878_6 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000002667 63.0
REGS2_k127_6162674_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.454e-230 749.0
REGS2_k127_6162674_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
REGS2_k127_6162674_10 - - - - 0.00002053 56.0
REGS2_k127_6162674_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 348.0
REGS2_k127_6162674_4 threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 299.0
REGS2_k127_6162674_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000002083 240.0
REGS2_k127_6162674_6 Radical SAM superfamily - - - 0.000000000000000000000000000000000006724 156.0
REGS2_k127_6162674_7 methyltransferase K05928 - 2.1.1.95 0.0000000000000000001237 98.0
REGS2_k127_6162674_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000004359 91.0
REGS2_k127_6247932_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 372.0
REGS2_k127_6247932_1 N,N-dimethylaniline monooxygenase activity K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001984 244.0
REGS2_k127_6269692_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.426e-208 662.0
REGS2_k127_6269692_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 432.0
REGS2_k127_6269692_10 Sigma-70 region 2 K03088 - - 0.0000000000002469 81.0
REGS2_k127_6269692_11 Putative adhesin K11621 - - 0.000001012 54.0
REGS2_k127_6269692_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 415.0
REGS2_k127_6269692_3 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 367.0
REGS2_k127_6269692_4 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005633 255.0
REGS2_k127_6269692_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000001105 248.0
REGS2_k127_6269692_6 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000002367 205.0
REGS2_k127_6269692_7 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.0000000000000000000000000000000000000000000001119 181.0
REGS2_k127_6269692_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000001379 160.0
REGS2_k127_6269692_9 metal cluster binding - - - 0.0000000000000000000000000000000001203 142.0
REGS2_k127_6282680_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 598.0
REGS2_k127_6282680_1 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 533.0
REGS2_k127_6282680_10 ABC transporter permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 289.0
REGS2_k127_6282680_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000003734 274.0
REGS2_k127_6282680_12 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001096 265.0
REGS2_k127_6282680_13 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001256 253.0
REGS2_k127_6282680_14 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000003504 224.0
REGS2_k127_6282680_15 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000219 194.0
REGS2_k127_6282680_16 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000007575 182.0
REGS2_k127_6282680_17 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000001299 151.0
REGS2_k127_6282680_18 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.00000000000000000000000000000000001497 156.0
REGS2_k127_6282680_19 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002452 142.0
REGS2_k127_6282680_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 450.0
REGS2_k127_6282680_20 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000009243 131.0
REGS2_k127_6282680_21 Mannosyltransferase (PIG-V) - - - 0.00000000000000000000231 109.0
REGS2_k127_6282680_22 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000006696 78.0
REGS2_k127_6282680_24 Transcription factor zinc-finger K09981 - - 0.0000001111 59.0
REGS2_k127_6282680_25 His Kinase A (phosphoacceptor) domain - - - 0.0009196 50.0
REGS2_k127_6282680_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 399.0
REGS2_k127_6282680_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 372.0
REGS2_k127_6282680_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 386.0
REGS2_k127_6282680_6 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 369.0
REGS2_k127_6282680_7 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 342.0
REGS2_k127_6282680_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 334.0
REGS2_k127_6282680_9 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 319.0
REGS2_k127_63411_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 569.0
REGS2_k127_63411_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 432.0
REGS2_k127_63411_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 348.0
REGS2_k127_63411_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 299.0
REGS2_k127_63411_4 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004065 279.0
REGS2_k127_63411_5 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000129 269.0
REGS2_k127_63411_6 Histidine kinase - - - 0.000000000000000000000000000000000000000002159 173.0
REGS2_k127_63411_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000002011 121.0
REGS2_k127_63411_8 Pas domain - - - 0.0000000000000000000002615 106.0
REGS2_k127_63411_9 to Cytochrome c-554 precursor (C554) (Hydroxylamine oxidoreductase-linked cytochrome) pir A59036 cytochrome c554, tetraheme, precursor - Nitrosomonas europaea - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000002782 67.0
REGS2_k127_6361157_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 532.0
REGS2_k127_6361157_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000001221 175.0
REGS2_k127_6361157_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000001193 106.0
REGS2_k127_6361157_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001794 65.0
REGS2_k127_6361157_4 Outer membrane efflux protein - - - 0.00007297 55.0
REGS2_k127_6462422_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 487.0
REGS2_k127_6462422_1 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 394.0
REGS2_k127_6462422_2 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000006756 101.0
REGS2_k127_6472807_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 5.107e-195 632.0
REGS2_k127_6472807_1 beta-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 458.0
REGS2_k127_6472807_10 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000002143 198.0
REGS2_k127_6472807_11 YCII-related domain - - - 0.00000000000000000000001143 105.0
REGS2_k127_6472807_12 membrane K00389 - - 0.00000000000000009284 85.0
REGS2_k127_6472807_13 Cytochrome c K03889 - - 0.000004132 60.0
REGS2_k127_6472807_14 peptidyl-tyrosine sulfation - - - 0.000006756 58.0
REGS2_k127_6472807_2 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 398.0
REGS2_k127_6472807_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 392.0
REGS2_k127_6472807_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 386.0
REGS2_k127_6472807_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
REGS2_k127_6472807_6 short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000044 289.0
REGS2_k127_6472807_7 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003726 246.0
REGS2_k127_6472807_8 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000002315 209.0
REGS2_k127_6472807_9 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000000000001259 207.0
REGS2_k127_6524981_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 451.0
REGS2_k127_6524981_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000005784 255.0
REGS2_k127_6524981_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000001237 239.0
REGS2_k127_6524981_3 Sigma factor PP2C-like phosphatases K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000002045 213.0
REGS2_k127_6556206_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 614.0
REGS2_k127_6556206_1 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004421 273.0
REGS2_k127_6556206_2 response regulator - - - 0.00000000000000000000000000000000000000000007215 175.0
REGS2_k127_6576582_0 Belongs to the glycosyl hydrolase 2 family - - - 3.368e-278 867.0
REGS2_k127_6576582_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 492.0
REGS2_k127_6576582_2 DNA primase activity - - - 0.00000000000000000000000000000000000000000000000000000002519 202.0
REGS2_k127_658150_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.401e-242 777.0
REGS2_k127_658150_1 Heat shock 70 kDa protein K04043 - - 2.377e-236 745.0
REGS2_k127_658150_10 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009081 270.0
REGS2_k127_658150_11 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002363 267.0
REGS2_k127_658150_12 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000001622 250.0
REGS2_k127_658150_13 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000001983 243.0
REGS2_k127_658150_14 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000001631 234.0
REGS2_k127_658150_15 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.00000000000000000000000000000000000000000000000004238 200.0
REGS2_k127_658150_16 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000001033 178.0
REGS2_k127_658150_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000001169 180.0
REGS2_k127_658150_18 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000001877 170.0
REGS2_k127_658150_19 Diguanylate cyclase - - - 0.000000000000000000000000000000000398 145.0
REGS2_k127_658150_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 529.0
REGS2_k127_658150_20 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000007771 140.0
REGS2_k127_658150_21 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000005876 132.0
REGS2_k127_658150_22 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000001124 117.0
REGS2_k127_658150_23 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000001354 122.0
REGS2_k127_658150_24 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000001777 93.0
REGS2_k127_658150_25 Domain of unknown function (DUF2520) - - - 0.0000000000000009311 87.0
REGS2_k127_658150_26 Multidrug ABC transporter ATP-binding protein K18216,K18889 - - 0.0000000000001219 72.0
REGS2_k127_658150_27 ABC transporter transmembrane region K11085 - - 0.000000000008351 78.0
REGS2_k127_658150_28 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000002106 68.0
REGS2_k127_658150_29 tRNA wobble adenosine to inosine editing - - - 0.0000001919 57.0
REGS2_k127_658150_3 (ABC) transporter K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 442.0
REGS2_k127_658150_30 Tetratricopeptide TPR_2 repeat protein - - - 0.000361 53.0
REGS2_k127_658150_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 418.0
REGS2_k127_658150_5 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 414.0
REGS2_k127_658150_6 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 395.0
REGS2_k127_658150_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
REGS2_k127_658150_8 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 331.0
REGS2_k127_658150_9 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 304.0
REGS2_k127_6623867_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004058 257.0
REGS2_k127_6623867_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0001406 55.0
REGS2_k127_6935652_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1352.0
REGS2_k127_6935652_1 Belongs to the peptidase M16 family K07263 - - 0.0 1108.0
REGS2_k127_6935652_10 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 336.0
REGS2_k127_6935652_11 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K21784 GO:0003674,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0048037,GO:0070279,GO:0070280,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 329.0
REGS2_k127_6935652_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 317.0
REGS2_k127_6935652_13 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 320.0
REGS2_k127_6935652_14 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 308.0
REGS2_k127_6935652_15 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 314.0
REGS2_k127_6935652_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
REGS2_k127_6935652_17 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006777 295.0
REGS2_k127_6935652_18 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007786 272.0
REGS2_k127_6935652_19 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002853 243.0
REGS2_k127_6935652_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 9.293e-238 788.0
REGS2_k127_6935652_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000316 232.0
REGS2_k127_6935652_21 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.000000000000000000000000000000000000000000000000004298 194.0
REGS2_k127_6935652_22 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000002929 171.0
REGS2_k127_6935652_23 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000004785 176.0
REGS2_k127_6935652_24 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000007434 170.0
REGS2_k127_6935652_25 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000001098 143.0
REGS2_k127_6935652_26 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000007806 156.0
REGS2_k127_6935652_27 diguanylate cyclase - - - 0.000000000000000000000000000000000618 144.0
REGS2_k127_6935652_28 Adenylylsulfate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000002953 138.0
REGS2_k127_6935652_29 FtsX-like permease family K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944 - 0.0000000000000000000335 106.0
REGS2_k127_6935652_3 Involved in the tonB-independent uptake of proteins - - - 1.476e-207 679.0
REGS2_k127_6935652_30 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000006521 98.0
REGS2_k127_6935652_31 SMART regulatory protein, MerR - - - 0.0000000000000000001121 103.0
REGS2_k127_6935652_32 Alpha beta hydrolase - - - 0.000000000000005032 83.0
REGS2_k127_6935652_33 Protein tyrosine kinase - - - 0.0000003157 54.0
REGS2_k127_6935652_34 - - - - 0.00002069 54.0
REGS2_k127_6935652_35 Forkhead associated domain - - - 0.00003632 53.0
REGS2_k127_6935652_36 N-acetyltransferase - - - 0.0006243 51.0
REGS2_k127_6935652_4 ADP binding - - - 2.134e-196 649.0
REGS2_k127_6935652_5 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 609.0
REGS2_k127_6935652_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 592.0
REGS2_k127_6935652_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 487.0
REGS2_k127_6935652_8 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
REGS2_k127_6935652_9 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 341.0
REGS2_k127_6953459_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.201e-262 822.0
REGS2_k127_6953459_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 503.0
REGS2_k127_6953459_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000003188 200.0
REGS2_k127_6953459_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000004137 189.0
REGS2_k127_6953459_12 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000003146 183.0
REGS2_k127_6953459_13 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000002059 162.0
REGS2_k127_6953459_14 WYL domain K13572 - - 0.0000000000000000000000000000000000000000254 165.0
REGS2_k127_6953459_15 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000002814 166.0
REGS2_k127_6953459_16 SAM-dependent methyltransferase - - - 0.000000000000000000000000000000000005924 143.0
REGS2_k127_6953459_17 cell redox homeostasis - - - 0.0000000000000000000000001158 116.0
REGS2_k127_6953459_18 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000004688 92.0
REGS2_k127_6953459_19 Preprotein translocase SecG subunit K03075 - - 0.0000000000000002459 83.0
REGS2_k127_6953459_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 434.0
REGS2_k127_6953459_20 Putative adhesin - - - 0.000000004351 66.0
REGS2_k127_6953459_21 TQO small subunit DoxD K16937 - 1.8.5.2 0.000000008573 63.0
REGS2_k127_6953459_22 transcriptional regulator K22491 - - 0.0000005342 57.0
REGS2_k127_6953459_23 TPR repeat - - - 0.000002111 60.0
REGS2_k127_6953459_3 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 421.0
REGS2_k127_6953459_4 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 419.0
REGS2_k127_6953459_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 390.0
REGS2_k127_6953459_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 366.0
REGS2_k127_6953459_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 302.0
REGS2_k127_6953459_8 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000001615 228.0
REGS2_k127_6953459_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000001072 191.0
REGS2_k127_697970_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 584.0
REGS2_k127_697970_1 Radical SAM superfamily - - - 0.0000000000000000000000002417 119.0
REGS2_k127_697970_2 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.00000005459 66.0
REGS2_k127_697970_3 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0006157 51.0
REGS2_k127_6979772_0 peptidyl-tyrosine sulfation - - - 3.608e-216 691.0
REGS2_k127_6979772_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 582.0
REGS2_k127_6979772_10 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000295 213.0
REGS2_k127_6979772_11 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000002138 200.0
REGS2_k127_6979772_12 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000007168 149.0
REGS2_k127_6979772_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.000000000000000000000000000000000004487 147.0
REGS2_k127_6979772_14 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000002593 124.0
REGS2_k127_6979772_15 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000266 118.0
REGS2_k127_6979772_16 Transcriptional regulator - - - 0.0000000000000000003739 93.0
REGS2_k127_6979772_17 Methylamine utilisation protein MauE - - - 0.0000000000000000004262 99.0
REGS2_k127_6979772_18 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000004306 85.0
REGS2_k127_6979772_19 ABC-2 family transporter protein K19341 - - 0.0000003794 62.0
REGS2_k127_6979772_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 501.0
REGS2_k127_6979772_20 - - - - 0.0002323 46.0
REGS2_k127_6979772_3 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 470.0
REGS2_k127_6979772_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 444.0
REGS2_k127_6979772_5 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 406.0
REGS2_k127_6979772_6 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 383.0
REGS2_k127_6979772_7 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 371.0
REGS2_k127_6979772_8 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001053 297.0
REGS2_k127_6979772_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 272.0
REGS2_k127_7048984_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004956 282.0
REGS2_k127_7048984_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000113 215.0
REGS2_k127_7048984_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000001029 177.0
REGS2_k127_7048984_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000008078 167.0
REGS2_k127_7048984_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000004134 123.0
REGS2_k127_7048984_5 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000009479 108.0
REGS2_k127_7048984_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000002156 102.0
REGS2_k127_7048984_7 outer membrane autotransporter barrel domain protein - - - 0.000000000000002056 84.0
REGS2_k127_7048984_8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000005376 74.0
REGS2_k127_7048984_9 Glutaredoxin-like domain (DUF836) - - - 0.000000002043 68.0
REGS2_k127_7137049_0 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 574.0
REGS2_k127_7137049_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 328.0
REGS2_k127_7147702_0 pyrroloquinoline quinone binding - - - 8.073e-198 624.0
REGS2_k127_7147702_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 618.0
REGS2_k127_7147702_10 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000007209 216.0
REGS2_k127_7147702_11 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000004431 210.0
REGS2_k127_7147702_12 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000001068 203.0
REGS2_k127_7147702_13 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000124 158.0
REGS2_k127_7147702_14 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000000000000000000003521 154.0
REGS2_k127_7147702_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000000000000000000000000000000551 126.0
REGS2_k127_7147702_16 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000354 123.0
REGS2_k127_7147702_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441,K03522 - 1.12.98.1,1.2.7.1 0.0000000000000000000000005533 109.0
REGS2_k127_7147702_18 Aldo Keto reductase - - - 0.00000000000000000000000164 107.0
REGS2_k127_7147702_19 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.0000000000001284 74.0
REGS2_k127_7147702_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 602.0
REGS2_k127_7147702_20 Radical SAM superfamily - - - 0.000006674 50.0
REGS2_k127_7147702_21 PFAM PBS lyase HEAT-like repeat K02288 - 4.4.1.32 0.00004389 56.0
REGS2_k127_7147702_3 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 587.0
REGS2_k127_7147702_4 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 548.0
REGS2_k127_7147702_5 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 424.0
REGS2_k127_7147702_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 363.0
REGS2_k127_7147702_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 364.0
REGS2_k127_7147702_8 histone deacetylase K11407 GO:0003674,GO:0003824,GO:0004407,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006325,GO:0006338,GO:0006464,GO:0006476,GO:0006807,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009653,GO:0009888,GO:0009987,GO:0010015,GO:0010053,GO:0016043,GO:0016569,GO:0016570,GO:0016575,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019538,GO:0022622,GO:0030154,GO:0030856,GO:0032501,GO:0032502,GO:0033558,GO:0035601,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0045595,GO:0045604,GO:0045682,GO:0048364,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0051239,GO:0051276,GO:0065007,GO:0071704,GO:0071840,GO:0090558,GO:0090627,GO:0098732,GO:0099402,GO:0140096,GO:1901564,GO:1905392,GO:2000026 3.5.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 327.0
REGS2_k127_7147702_9 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 300.0
REGS2_k127_7150763_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 422.0
REGS2_k127_7150763_1 S4 RNA-binding domain K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 291.0
REGS2_k127_7150763_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000005857 219.0
REGS2_k127_7150763_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000003504 139.0
REGS2_k127_7150763_4 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000001196 57.0
REGS2_k127_7196479_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 477.0
REGS2_k127_7196479_1 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 452.0
REGS2_k127_7196479_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 330.0
REGS2_k127_7196479_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004267 280.0
REGS2_k127_7196479_4 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000006279 243.0
REGS2_k127_7196479_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000001443 199.0
REGS2_k127_7196479_6 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000005218 167.0
REGS2_k127_7196479_7 TIGR00255 family - - - 0.000000000000000000000000000000000000000001939 180.0
REGS2_k127_7196479_8 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000007562 48.0
REGS2_k127_7222339_0 Sortilin, neurotensin receptor 3, - - - 0.0 1237.0
REGS2_k127_7222339_1 Peptidase dimerisation domain - - - 9.754e-206 651.0
REGS2_k127_7222339_2 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 377.0
REGS2_k127_7222339_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000001905 198.0
REGS2_k127_7222339_4 - - - - 0.00000000000000000000000000000000000223 144.0
REGS2_k127_7222339_5 glyoxalase III activity - - - 0.000000000000000000000000000000000006589 159.0
REGS2_k127_7222339_6 COG0659 Sulfate permease and related transporters (MFS K01673,K03321 - 4.2.1.1 0.00000000001765 70.0
REGS2_k127_7222339_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509 - 0.000408 52.0
REGS2_k127_7274270_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1205.0
REGS2_k127_7274270_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 9.375e-292 906.0
REGS2_k127_7274270_10 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
REGS2_k127_7274270_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000000000000919 199.0
REGS2_k127_7274270_12 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001965 190.0
REGS2_k127_7274270_13 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000000000000000000000000000000000000007828 180.0
REGS2_k127_7274270_14 Haem-degrading - - - 0.00000000000000000000000000000000000002711 148.0
REGS2_k127_7274270_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001499 85.0
REGS2_k127_7274270_17 - - - - 0.000000000001962 70.0
REGS2_k127_7274270_18 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000002463 69.0
REGS2_k127_7274270_19 Carboxypeptidase regulatory-like domain - - - 0.00000009913 58.0
REGS2_k127_7274270_2 Protein kinase domain K12132 - 2.7.11.1 1.709e-279 898.0
REGS2_k127_7274270_20 Carboxylesterase family - - - 0.000002102 60.0
REGS2_k127_7274270_22 Protein tyrosine kinase K12132 - 2.7.11.1 0.0001105 50.0
REGS2_k127_7274270_23 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0003104 53.0
REGS2_k127_7274270_3 PFAM Prolyl oligopeptidase family - - - 1.524e-248 784.0
REGS2_k127_7274270_4 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 515.0
REGS2_k127_7274270_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 512.0
REGS2_k127_7274270_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 417.0
REGS2_k127_7274270_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 368.0
REGS2_k127_7274270_8 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001577 282.0
REGS2_k127_7274270_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003136 268.0
REGS2_k127_7396517_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 526.0
REGS2_k127_7396517_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 402.0
REGS2_k127_7396517_10 Transcriptional regulator K07729 - - 0.000000000000000007262 85.0
REGS2_k127_7396517_11 Plasmid stability protein - - - 0.00000001083 66.0
REGS2_k127_7396517_12 - - - - 0.000001926 59.0
REGS2_k127_7396517_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 350.0
REGS2_k127_7396517_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000001257 235.0
REGS2_k127_7396517_4 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000002041 218.0
REGS2_k127_7396517_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.000000000000000000000000000000000000000000007353 167.0
REGS2_k127_7396517_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000001483 182.0
REGS2_k127_7396517_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000002879 177.0
REGS2_k127_7396517_8 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000002921 157.0
REGS2_k127_7396517_9 NIPSNAP family containing protein - - - 0.00000000000000000000000000000003056 140.0
REGS2_k127_7435669_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 513.0
REGS2_k127_7435669_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 462.0
REGS2_k127_7435669_10 NHL repeat - - - 0.000000000000000000000000005586 131.0
REGS2_k127_7435669_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000003491 108.0
REGS2_k127_7435669_2 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 359.0
REGS2_k127_7435669_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 323.0
REGS2_k127_7435669_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 311.0
REGS2_k127_7435669_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000012 236.0
REGS2_k127_7435669_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000008312 207.0
REGS2_k127_7435669_7 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000004206 190.0
REGS2_k127_7435669_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000105 168.0
REGS2_k127_7435669_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000002317 127.0
REGS2_k127_7549931_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000008401 60.0
REGS2_k127_7549931_1 Heavy-metal resistance - - - 0.000002069 59.0
REGS2_k127_7561039_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 384.0
REGS2_k127_7561039_1 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000003876 195.0
REGS2_k127_7561039_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000001459 186.0
REGS2_k127_7561039_3 PFAM aldo keto reductase - - - 0.00000000000000000001747 100.0
REGS2_k127_7568866_0 Belongs to the major facilitator superfamily K07001 - - 0.0000000000000000192 89.0
REGS2_k127_7568866_1 ATP:ADP antiporter activity K03301 - - 0.0000002006 64.0
REGS2_k127_7642285_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 514.0
REGS2_k127_7642285_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 330.0
REGS2_k127_7642285_10 Methyltransferase domain - - - 0.000000000000000000003727 102.0
REGS2_k127_7642285_11 Regulatory protein, FmdB - - - 0.000000000000000001656 90.0
REGS2_k127_7642285_12 phosphorelay signal transduction system - - - 0.000000000003781 76.0
REGS2_k127_7642285_13 Alpha/beta hydrolase family - - - 0.0000000755 66.0
REGS2_k127_7642285_2 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001665 286.0
REGS2_k127_7642285_3 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000002715 230.0
REGS2_k127_7642285_4 TIGRFAM molybdenum cofactor synthesis domain K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000004957 231.0
REGS2_k127_7642285_5 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000005458 196.0
REGS2_k127_7642285_6 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000001457 187.0
REGS2_k127_7642285_7 FAD binding domain - - - 0.000000000000000000000000000000000000000000001589 180.0
REGS2_k127_7642285_8 Two component regulator propeller - - - 0.0000000000000000000000000000000007697 151.0
REGS2_k127_7642285_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000001495 109.0
REGS2_k127_7648684_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 496.0
REGS2_k127_7648684_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 469.0
REGS2_k127_7648684_10 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000001799 113.0
REGS2_k127_7648684_11 Thioesterase-like superfamily K07107 - - 0.000000000000002638 89.0
REGS2_k127_7648684_12 response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000004552 81.0
REGS2_k127_7648684_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 345.0
REGS2_k127_7648684_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 312.0
REGS2_k127_7648684_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000001354 244.0
REGS2_k127_7648684_5 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000009086 223.0
REGS2_k127_7648684_6 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000005322 161.0
REGS2_k127_7648684_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.00000000000000000000000000001907 132.0
REGS2_k127_7648684_8 Biogenesis protein - - - 0.000000000000000000000000002372 123.0
REGS2_k127_7648684_9 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000007186 122.0
REGS2_k127_7688370_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000762 253.0
REGS2_k127_7688370_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000004649 151.0
REGS2_k127_7745290_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 1.066e-300 946.0
REGS2_k127_7745290_1 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 344.0
REGS2_k127_7745290_2 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 294.0
REGS2_k127_7745290_3 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000639 282.0
REGS2_k127_7745290_4 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000002273 207.0
REGS2_k127_7745290_5 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K02075,K09816 - - 0.0000000000000000000006636 105.0
REGS2_k127_7745290_6 Protein of unknown function (DUF1622) - - - 0.000000000000000000003485 97.0
REGS2_k127_7745290_7 Universal stress protein - - - 0.000000000000000001341 94.0
REGS2_k127_7745290_8 CBS domain K04767 - - 0.000000000000000002798 91.0
REGS2_k127_7745290_9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07694,K11618 - - 0.000000000261 69.0
REGS2_k127_7758033_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 521.0
REGS2_k127_7758033_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 492.0
REGS2_k127_7758033_10 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000001158 262.0
REGS2_k127_7758033_11 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001514 259.0
REGS2_k127_7758033_12 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000006117 215.0
REGS2_k127_7758033_13 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000005847 217.0
REGS2_k127_7758033_14 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000005314 197.0
REGS2_k127_7758033_15 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000001879 193.0
REGS2_k127_7758033_16 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000005976 136.0
REGS2_k127_7758033_17 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000008669 121.0
REGS2_k127_7758033_18 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000002687 115.0
REGS2_k127_7758033_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000521 115.0
REGS2_k127_7758033_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 472.0
REGS2_k127_7758033_20 Protein of unknown function DUF58 - - - 0.000000000000000000000007104 113.0
REGS2_k127_7758033_21 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000002559 108.0
REGS2_k127_7758033_23 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000001995 97.0
REGS2_k127_7758033_24 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000783 103.0
REGS2_k127_7758033_25 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000003238 84.0
REGS2_k127_7758033_26 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000003973 77.0
REGS2_k127_7758033_3 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 443.0
REGS2_k127_7758033_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 395.0
REGS2_k127_7758033_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 330.0
REGS2_k127_7758033_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 325.0
REGS2_k127_7758033_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 323.0
REGS2_k127_7758033_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 297.0
REGS2_k127_7758033_9 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000002749 274.0
REGS2_k127_7775164_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000006088 173.0
REGS2_k127_7775164_1 CAAX protease self-immunity K07052 - - 0.00000000000000000008817 98.0
REGS2_k127_7775164_2 - - - - 0.0006667 44.0
REGS2_k127_7800434_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 503.0
REGS2_k127_7800434_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 457.0
REGS2_k127_7800434_10 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004774 252.0
REGS2_k127_7800434_11 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
REGS2_k127_7800434_12 cheY-homologous receiver domain - - - 0.000000000000000002678 91.0
REGS2_k127_7800434_14 chloride channel K03281 - - 0.0000000001454 71.0
REGS2_k127_7800434_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 413.0
REGS2_k127_7800434_3 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 393.0
REGS2_k127_7800434_4 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 381.0
REGS2_k127_7800434_5 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 378.0
REGS2_k127_7800434_6 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 321.0
REGS2_k127_7800434_7 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 302.0
REGS2_k127_7800434_8 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 302.0
REGS2_k127_7800434_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003453 293.0
REGS2_k127_7806265_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000003235 161.0
REGS2_k127_7806265_1 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000001203 66.0
REGS2_k127_7830872_0 malic protein domain protein K00029 - 1.1.1.40 4.417e-297 929.0
REGS2_k127_7830872_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 587.0
REGS2_k127_7830872_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001827 242.0
REGS2_k127_7830872_11 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000001512 193.0
REGS2_k127_7830872_12 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000001317 185.0
REGS2_k127_7830872_13 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000001519 151.0
REGS2_k127_7830872_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000001613 152.0
REGS2_k127_7830872_15 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000002993 142.0
REGS2_k127_7830872_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000007633 124.0
REGS2_k127_7830872_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000002679 133.0
REGS2_k127_7830872_18 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000003506 120.0
REGS2_k127_7830872_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 535.0
REGS2_k127_7830872_20 Tetratricopeptide repeat - - - 0.00000000001111 78.0
REGS2_k127_7830872_21 Polymer-forming cytoskeletal - - - 0.0003699 53.0
REGS2_k127_7830872_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 476.0
REGS2_k127_7830872_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
REGS2_k127_7830872_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 329.0
REGS2_k127_7830872_6 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 289.0
REGS2_k127_7830872_7 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002798 289.0
REGS2_k127_7830872_8 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003939 259.0
REGS2_k127_7830872_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000006257 241.0
REGS2_k127_7867978_0 Amino acid permease - - - 5.403e-224 716.0
REGS2_k127_7867978_1 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 344.0
REGS2_k127_7867978_2 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001143 222.0
REGS2_k127_7867978_3 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000009004 212.0
REGS2_k127_7867978_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000636 205.0
REGS2_k127_7896537_0 protein secretion by the type I secretion system K11085 - - 1.383e-202 651.0
REGS2_k127_7896537_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 563.0
REGS2_k127_7896537_10 PFAM membrane protein of K08972 - - 0.000000000000000000000000000002803 123.0
REGS2_k127_7896537_11 - - - - 0.000000000000000000000000000008725 121.0
REGS2_k127_7896537_12 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000001301 120.0
REGS2_k127_7896537_13 PFAM CBS domain containing protein - - - 0.000000000000000000000007347 108.0
REGS2_k127_7896537_14 unusual protein kinase K03688 - - 0.00000000000000000000001102 106.0
REGS2_k127_7896537_16 Domain of unknown function (DUF4258) - - - 0.000000000000000000003097 100.0
REGS2_k127_7896537_2 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 432.0
REGS2_k127_7896537_3 peptidoglycan-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 380.0
REGS2_k127_7896537_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 271.0
REGS2_k127_7896537_5 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000001871 216.0
REGS2_k127_7896537_6 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000001195 192.0
REGS2_k127_7896537_7 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000000003252 201.0
REGS2_k127_7896537_8 photosynthesis - - - 0.0000000000000000000000000000000000000001438 161.0
REGS2_k127_7906483_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 7.165e-244 762.0
REGS2_k127_7906483_1 adenylosuccinate lyase K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 503.0
REGS2_k127_7906483_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000003028 128.0
REGS2_k127_7906483_11 - - - - 0.0000000000000000000003725 99.0
REGS2_k127_7906483_12 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000218 88.0
REGS2_k127_7906483_13 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000001798 81.0
REGS2_k127_7906483_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 354.0
REGS2_k127_7906483_3 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 334.0
REGS2_k127_7906483_4 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 326.0
REGS2_k127_7906483_5 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
REGS2_k127_7906483_6 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000007131 211.0
REGS2_k127_7906483_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001136 218.0
REGS2_k127_7906483_8 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000001967 194.0
REGS2_k127_7906483_9 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000003496 170.0
REGS2_k127_8053858_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 8.126e-286 903.0
REGS2_k127_8053858_1 Acetyl propionyl-CoA carboxylase, alpha subunit K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 484.0
REGS2_k127_8053858_2 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
REGS2_k127_8053858_3 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000003992 247.0
REGS2_k127_8053858_4 response regulator - - - 0.000000000000000000000000000000000000002733 162.0
REGS2_k127_8053858_5 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.00000000000003245 86.0
REGS2_k127_8054758_0 DEAD DEAH box K03724 - - 0.0 1974.0
REGS2_k127_8054758_1 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 648.0
REGS2_k127_8054758_10 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000002003 140.0
REGS2_k127_8054758_11 Peptidase MA superfamily - - - 0.00000000000000000000000009146 121.0
REGS2_k127_8054758_12 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000001378 121.0
REGS2_k127_8054758_13 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000001011 74.0
REGS2_k127_8054758_14 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.00000000721 66.0
REGS2_k127_8054758_15 peptidyl-tyrosine sulfation - - - 0.0003731 52.0
REGS2_k127_8054758_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
REGS2_k127_8054758_3 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 396.0
REGS2_k127_8054758_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 372.0
REGS2_k127_8054758_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 371.0
REGS2_k127_8054758_6 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 346.0
REGS2_k127_8054758_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 324.0
REGS2_k127_8054758_8 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000001425 241.0
REGS2_k127_8054758_9 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000003339 194.0
REGS2_k127_8091930_0 Sortilin, neurotensin receptor 3, - - - 0.0 1172.0
REGS2_k127_8091930_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.73e-310 962.0
REGS2_k127_8091930_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.352e-197 640.0
REGS2_k127_8091930_3 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 601.0
REGS2_k127_8091930_4 PFAM GGDEF domain containing protein, response regulator receiver - - - 0.000000000000000000000000000003404 131.0
REGS2_k127_8091930_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000003473 122.0
REGS2_k127_8091930_6 PFAM GGDEF domain containing protein - - - 0.00000003163 63.0
REGS2_k127_8091930_7 helix_turn_helix, Lux Regulon - - - 0.0000001039 62.0
REGS2_k127_8151711_0 Belongs to the ClpA ClpB family K03696 - - 1.215e-283 893.0
REGS2_k127_8151711_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.949e-273 878.0
REGS2_k127_8151711_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000008741 271.0
REGS2_k127_8151711_11 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007697 272.0
REGS2_k127_8151711_12 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000008158 243.0
REGS2_k127_8151711_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000104 221.0
REGS2_k127_8151711_14 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000001301 203.0
REGS2_k127_8151711_15 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000005876 192.0
REGS2_k127_8151711_16 OmpA family K03640 - - 0.0000000000000000000000000000000000000007632 156.0
REGS2_k127_8151711_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000001559 131.0
REGS2_k127_8151711_18 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000009917 123.0
REGS2_k127_8151711_19 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000003464 128.0
REGS2_k127_8151711_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 339.0
REGS2_k127_8151711_20 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000007258 122.0
REGS2_k127_8151711_21 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000001693 111.0
REGS2_k127_8151711_22 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000009574 106.0
REGS2_k127_8151711_23 TonB C terminal K03646,K03832 - - 0.0000000000009393 77.0
REGS2_k127_8151711_24 Transglutaminase/protease-like homologues - - - 0.000000003016 68.0
REGS2_k127_8151711_25 Ribosomal protein S20 K02968 - - 0.00000001446 60.0
REGS2_k127_8151711_26 outer membrane chaperone Skp (OmpH) K06142 - - 0.0001447 52.0
REGS2_k127_8151711_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 348.0
REGS2_k127_8151711_4 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 327.0
REGS2_k127_8151711_5 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 341.0
REGS2_k127_8151711_6 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 303.0
REGS2_k127_8151711_7 transport systems K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004796 282.0
REGS2_k127_8151711_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000003285 279.0
REGS2_k127_8151711_9 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 267.0
REGS2_k127_8165626_0 4Fe-4S single cluster domain K06937 - - 1.303e-248 782.0
REGS2_k127_8165626_1 PFAM Protein synthesis factor, GTP-binding K06207 - - 1.942e-197 661.0
REGS2_k127_8165626_10 phosphotransferase related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000001386 108.0
REGS2_k127_8165626_11 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008584 102.0
REGS2_k127_8165626_2 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 609.0
REGS2_k127_8165626_3 Organic Anion Transporter Polypeptide (OATP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 452.0
REGS2_k127_8165626_4 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 430.0
REGS2_k127_8165626_5 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 326.0
REGS2_k127_8165626_6 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000006565 250.0
REGS2_k127_8165626_7 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000001539 253.0
REGS2_k127_8165626_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000004971 202.0
REGS2_k127_8165626_9 methyltransferase K00563,K10947 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.0000000000000000000000000000000000000000001255 172.0
REGS2_k127_8352775_0 DinB family - - - 0.0000000000001337 78.0
REGS2_k127_8352775_1 DinB family - - - 0.000000003583 63.0
REGS2_k127_8444692_0 Amino acid permease - - - 4.567e-210 673.0
REGS2_k127_8444692_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 355.0
REGS2_k127_8444692_2 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000004654 186.0
REGS2_k127_8446480_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 457.0
REGS2_k127_8446480_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 333.0
REGS2_k127_8446480_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001676 280.0
REGS2_k127_8446480_3 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000002428 251.0
REGS2_k127_8446480_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002395 247.0
REGS2_k127_8446480_5 cation efflux K16264 - - 0.000000000000000000000000000000000000000000000000000000000009792 222.0
REGS2_k127_8446480_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000009765 167.0
REGS2_k127_8446480_7 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000001512 156.0
REGS2_k127_8446480_8 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000002905 130.0
REGS2_k127_8446480_9 Cytochrome c - - - 0.00000000000000000000000000003433 124.0
REGS2_k127_846212_0 Urocanase C-terminal domain K01712 - 4.2.1.49 2.19e-245 772.0
REGS2_k127_846212_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.709e-216 699.0
REGS2_k127_846212_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000001486 161.0
REGS2_k127_846212_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000001644 154.0
REGS2_k127_846212_12 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.00000000000000000000000000000000000002092 166.0
REGS2_k127_846212_13 repeat-containing protein - - - 0.00000000000000000000000000000000003692 154.0
REGS2_k127_846212_14 Could be involved in septation K06412 - - 0.000000000000000000000000000004857 134.0
REGS2_k127_846212_15 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000001452 115.0
REGS2_k127_846212_16 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000002485 116.0
REGS2_k127_846212_17 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000004491 106.0
REGS2_k127_846212_18 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000001815 91.0
REGS2_k127_846212_19 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.00004162 56.0
REGS2_k127_846212_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 464.0
REGS2_k127_846212_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 418.0
REGS2_k127_846212_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 329.0
REGS2_k127_846212_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000183 221.0
REGS2_k127_846212_6 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000000005839 233.0
REGS2_k127_846212_7 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000001159 211.0
REGS2_k127_846212_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000005025 181.0
REGS2_k127_846212_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000002948 163.0
REGS2_k127_8526105_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 347.0
REGS2_k127_8526105_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000007817 93.0
REGS2_k127_916446_0 FAD linked oxidases, C-terminal domain K06911 - - 0.0 1281.0
REGS2_k127_916446_1 4Fe-4S dicluster domain K00184 - - 0.0 1052.0
REGS2_k127_916446_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 330.0
REGS2_k127_916446_11 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 310.0
REGS2_k127_916446_12 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 304.0
REGS2_k127_916446_13 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 290.0
REGS2_k127_916446_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002395 267.0
REGS2_k127_916446_15 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
REGS2_k127_916446_16 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002936 254.0
REGS2_k127_916446_17 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000002988 243.0
REGS2_k127_916446_18 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
REGS2_k127_916446_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000005288 232.0
REGS2_k127_916446_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.598e-278 882.0
REGS2_k127_916446_20 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000001267 241.0
REGS2_k127_916446_21 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000007077 216.0
REGS2_k127_916446_22 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000001165 207.0
REGS2_k127_916446_23 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000005347 199.0
REGS2_k127_916446_24 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.0000000000000000000000000000000000000000157 161.0
REGS2_k127_916446_25 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000004108 144.0
REGS2_k127_916446_26 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000004363 139.0
REGS2_k127_916446_27 PFAM HD domain - - - 0.00000000000000000000000000001712 131.0
REGS2_k127_916446_28 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000001404 127.0
REGS2_k127_916446_29 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000008579 102.0
REGS2_k127_916446_3 Polysulphide reductase, NrfD K00185 - - 5.426e-215 684.0
REGS2_k127_916446_30 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000000000006331 99.0
REGS2_k127_916446_31 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001262 99.0
REGS2_k127_916446_32 Virulence activator alpha C-term - - - 0.00000000000000001115 89.0
REGS2_k127_916446_33 with different specificities (related to short-chain alcohol K00034 - 1.1.1.47 0.00000000000002749 79.0
REGS2_k127_916446_34 Putative MetA-pathway of phenol degradation - - - 0.0000000002367 72.0
REGS2_k127_916446_35 - - - - 0.000000009733 64.0
REGS2_k127_916446_36 Domain of unknown function (DUF4149) - - - 0.00000001085 64.0
REGS2_k127_916446_37 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.000004097 57.0
REGS2_k127_916446_38 - - - - 0.00005017 54.0
REGS2_k127_916446_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 434.0
REGS2_k127_916446_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 430.0
REGS2_k127_916446_6 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 349.0
REGS2_k127_916446_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 333.0
REGS2_k127_916446_8 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 331.0
REGS2_k127_916446_9 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 318.0
REGS2_k127_937418_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.313e-245 775.0
REGS2_k127_937418_1 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.296e-233 743.0
REGS2_k127_937418_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 342.0
REGS2_k127_937418_11 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 324.0
REGS2_k127_937418_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003354 263.0
REGS2_k127_937418_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002126 262.0
REGS2_k127_937418_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000007582 218.0
REGS2_k127_937418_15 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000001392 209.0
REGS2_k127_937418_16 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000008338 202.0
REGS2_k127_937418_17 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000001224 188.0
REGS2_k127_937418_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000002147 187.0
REGS2_k127_937418_19 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000036 190.0
REGS2_k127_937418_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.348e-209 685.0
REGS2_k127_937418_20 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000004127 174.0
REGS2_k127_937418_21 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000001711 148.0
REGS2_k127_937418_22 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000003655 141.0
REGS2_k127_937418_23 Methyltransferase domain - - - 0.000000000000000000000000000000000005622 149.0
REGS2_k127_937418_24 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000003169 136.0
REGS2_k127_937418_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001295 123.0
REGS2_k127_937418_26 Zn peptidase - - - 0.000000000000000000000000000005637 137.0
REGS2_k127_937418_27 STAS domain K04749 - - 0.00000000000000000000000000003075 132.0
REGS2_k127_937418_28 Glycosyl transferases group 1 - - - 0.00000000000000000000000000004372 132.0
REGS2_k127_937418_29 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000001274 115.0
REGS2_k127_937418_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 592.0
REGS2_k127_937418_30 Zincin-like metallopeptidase - - - 0.000000000000000000000003383 116.0
REGS2_k127_937418_31 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000004404 109.0
REGS2_k127_937418_32 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000107 97.0
REGS2_k127_937418_33 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000007872 89.0
REGS2_k127_937418_34 Protein of unknown function (DUF503) K09764 - - 0.000000000000006163 78.0
REGS2_k127_937418_35 Redoxin K03564 - 1.11.1.15 0.000000000003857 76.0
REGS2_k127_937418_36 Cell division protein ZapA K09888 - - 0.0000000003441 64.0
REGS2_k127_937418_37 Protein of unknown function (DUF2905) - - - 0.000000294 55.0
REGS2_k127_937418_38 TonB C terminal - - - 0.000001007 61.0
REGS2_k127_937418_39 alpha/beta hydrolase fold - - - 0.000008485 55.0
REGS2_k127_937418_4 mRNA catabolic process K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 548.0
REGS2_k127_937418_40 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K00641 - 2.3.1.31 0.00006319 49.0
REGS2_k127_937418_41 metal-dependent membrane protease K07052 - - 0.00006409 54.0
REGS2_k127_937418_5 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 480.0
REGS2_k127_937418_6 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 415.0
REGS2_k127_937418_7 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 377.0
REGS2_k127_937418_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 357.0
REGS2_k127_937418_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 362.0
REGS2_k127_998007_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 9.938e-268 850.0
REGS2_k127_998007_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 490.0
REGS2_k127_998007_10 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000007887 221.0
REGS2_k127_998007_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000002833 208.0
REGS2_k127_998007_12 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000008574 205.0
REGS2_k127_998007_13 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000006477 167.0
REGS2_k127_998007_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000008121 160.0
REGS2_k127_998007_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000008221 157.0
REGS2_k127_998007_16 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000002426 143.0
REGS2_k127_998007_17 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000006724 148.0
REGS2_k127_998007_18 iron ion homeostasis - - - 0.000000000000000000000000000000004528 148.0
REGS2_k127_998007_19 - - - - 0.0000000000000000000000000001116 128.0
REGS2_k127_998007_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 475.0
REGS2_k127_998007_20 Domain of unknown function (DUF4115) - - - 0.000000000000000000000005208 111.0
REGS2_k127_998007_21 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997,K18014 - 2.7.8.7,4.3.1.14 0.000000000000000000000005396 106.0
REGS2_k127_998007_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000008179 112.0
REGS2_k127_998007_23 - - - - 0.0000000000005965 79.0
REGS2_k127_998007_24 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000329 70.0
REGS2_k127_998007_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 434.0
REGS2_k127_998007_4 ATP-dependent helicase activity K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 421.0
REGS2_k127_998007_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 412.0
REGS2_k127_998007_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006263 287.0
REGS2_k127_998007_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000002899 265.0
REGS2_k127_998007_8 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000009766 231.0
REGS2_k127_998007_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000009672 229.0