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Overview

ID MAG03338
Name REGS2_bin.28
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family 2-12-FULL-66-21
Genus
Species
Assembly information
Completeness (%) 90.82
Contamination (%) 4.2
GC content (%) 66.0
N50 (bp) 10,879
Genome size (bp) 3,696,561

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3110

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1007733_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 590.0
REGS2_k127_1010138_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.969e-245 786.0
REGS2_k127_1010138_1 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000002013 147.0
REGS2_k127_1010138_2 peroxiredoxin activity K03564 - 1.11.1.15 0.000000001038 60.0
REGS2_k127_1010138_3 alkyl hydroperoxide reductase - - - 0.00000003876 55.0
REGS2_k127_1021563_0 COG0534 Na -driven multidrug efflux pump K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 396.0
REGS2_k127_1021563_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 394.0
REGS2_k127_1021563_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 301.0
REGS2_k127_1021563_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 302.0
REGS2_k127_1021563_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000001348 204.0
REGS2_k127_1021563_5 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000005707 138.0
REGS2_k127_1032528_0 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 560.0
REGS2_k127_1032528_1 ECF sigma factor K03088 - - 0.000000000000000000000000000000000009501 142.0
REGS2_k127_1032528_2 Polymer-forming cytoskeletal - - - 0.00000000001878 77.0
REGS2_k127_1044729_0 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 422.0
REGS2_k127_1044729_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000002348 209.0
REGS2_k127_1044729_2 anti-sigma regulatory factor - - - 0.0000000000000000000000000002541 118.0
REGS2_k127_1044729_3 helix_turn_helix, Lux Regulon - - - 0.000000000001952 71.0
REGS2_k127_1044729_4 Involved in the tonB-independent uptake of proteins - - - 0.00000008465 64.0
REGS2_k127_1056022_0 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003257 295.0
REGS2_k127_1056106_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000001345 233.0
REGS2_k127_1056106_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000004721 208.0
REGS2_k127_1056106_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000001089 193.0
REGS2_k127_1056106_3 - - - - 0.000000000000000000000005181 106.0
REGS2_k127_1056106_4 ribosomal protein - - - 0.00000000000007695 79.0
REGS2_k127_1056106_5 GGDEF FHA domain protein - - - 0.000000000001654 71.0
REGS2_k127_1062883_0 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 320.0
REGS2_k127_1062883_1 G/U mismatch-specific uracil-DNA glycosylase activity K01934,K03649 GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 0.000000000000000000000000000000000002608 144.0
REGS2_k127_1063885_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000001385 83.0
REGS2_k127_1081547_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 381.0
REGS2_k127_1081547_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
REGS2_k127_1104805_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 516.0
REGS2_k127_1104805_1 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 476.0
REGS2_k127_1104805_10 NUDIX domain - - - 0.0000000000000000000000000001632 124.0
REGS2_k127_1104805_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000001022 90.0
REGS2_k127_1104805_12 lyase activity - - - 0.000000002933 70.0
REGS2_k127_1104805_13 HEAT repeats - - - 0.0001105 55.0
REGS2_k127_1104805_2 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 466.0
REGS2_k127_1104805_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 417.0
REGS2_k127_1104805_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 324.0
REGS2_k127_1104805_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 299.0
REGS2_k127_1104805_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000002116 214.0
REGS2_k127_1104805_7 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000003698 228.0
REGS2_k127_1104805_8 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000003248 205.0
REGS2_k127_1104805_9 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000001756 171.0
REGS2_k127_1114339_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.598e-203 646.0
REGS2_k127_1114339_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 382.0
REGS2_k127_1114339_2 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 342.0
REGS2_k127_1114339_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 314.0
REGS2_k127_1114339_4 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000001017 158.0
REGS2_k127_1114339_5 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000002835 89.0
REGS2_k127_1123541_0 Putative carbohydrate binding domain K12373 - 3.2.1.52 3.162e-245 774.0
REGS2_k127_1123541_1 PFAM peptidase M13 K01415 - 3.4.24.71 5.823e-238 750.0
REGS2_k127_1123541_2 Peptidase S46 - - - 5.151e-226 722.0
REGS2_k127_1123541_3 Tricorn protease C1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 349.0
REGS2_k127_113305_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.749e-223 725.0
REGS2_k127_113305_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 579.0
REGS2_k127_113305_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000001507 211.0
REGS2_k127_113305_11 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000003871 216.0
REGS2_k127_113305_12 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000001991 173.0
REGS2_k127_113305_13 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000008858 174.0
REGS2_k127_113305_14 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000001077 180.0
REGS2_k127_113305_15 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000291 172.0
REGS2_k127_113305_16 molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000003798 153.0
REGS2_k127_113305_17 BioY family K03523 - - 0.00000000000000000000000000000000000003027 160.0
REGS2_k127_113305_18 Belongs to the HesB IscA family K13628,K15724 - - 0.000000000000000000000000000000001716 132.0
REGS2_k127_113305_19 Belongs to the Fur family K03711 - - 0.000000000000000000000000007966 124.0
REGS2_k127_113305_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 584.0
REGS2_k127_113305_20 ABC transporter, ATP-binding protein K02003 - - 0.00000000000000004678 91.0
REGS2_k127_113305_21 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000002816 87.0
REGS2_k127_113305_22 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.00000000000004292 75.0
REGS2_k127_113305_23 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000001234 81.0
REGS2_k127_113305_24 Cold shock protein domain - - - 0.000000000005337 72.0
REGS2_k127_113305_25 DUF218 domain - - - 0.0005274 50.0
REGS2_k127_113305_3 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 497.0
REGS2_k127_113305_4 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 476.0
REGS2_k127_113305_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 462.0
REGS2_k127_113305_6 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 450.0
REGS2_k127_113305_7 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 411.0
REGS2_k127_113305_8 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 279.0
REGS2_k127_113305_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000002774 216.0
REGS2_k127_1139658_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 535.0
REGS2_k127_1139658_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000001386 164.0
REGS2_k127_1139658_2 Psort location Cytoplasmic, score K01129 - 3.1.5.1 0.00000002535 55.0
REGS2_k127_1141412_0 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000129 184.0
REGS2_k127_1141412_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000005431 182.0
REGS2_k127_1141412_2 - - - - 0.000000000006452 78.0
REGS2_k127_1141412_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000001493 54.0
REGS2_k127_114874_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.344e-202 653.0
REGS2_k127_114874_1 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 490.0
REGS2_k127_114874_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000007697 146.0
REGS2_k127_114874_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000001189 104.0
REGS2_k127_114874_4 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000001694 90.0
REGS2_k127_114874_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000002415 73.0
REGS2_k127_1155107_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 547.0
REGS2_k127_1155107_1 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 379.0
REGS2_k127_1155107_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006629 243.0
REGS2_k127_1155107_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000006778 188.0
REGS2_k127_1160424_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1020.0
REGS2_k127_1160424_1 Hydrolase CocE NonD family - - - 9.4e-323 996.0
REGS2_k127_1160424_10 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 400.0
REGS2_k127_1160424_11 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 358.0
REGS2_k127_1160424_12 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 345.0
REGS2_k127_1160424_14 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005365 279.0
REGS2_k127_1160424_15 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000008424 231.0
REGS2_k127_1160424_16 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000001134 191.0
REGS2_k127_1160424_17 - - - - 0.00000000000000000000000000000000000000000000000003516 186.0
REGS2_k127_1160424_18 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000001692 138.0
REGS2_k127_1160424_19 methyltransferase - - - 0.00000000000000000000001165 117.0
REGS2_k127_1160424_2 Malate synthase K01638 - 2.3.3.9 1.709e-292 910.0
REGS2_k127_1160424_20 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000001343 61.0
REGS2_k127_1160424_3 peptidyl-tyrosine sulfation - - - 4.725e-240 754.0
REGS2_k127_1160424_4 amine dehydrogenase activity - - - 6.14e-240 757.0
REGS2_k127_1160424_5 B12 binding domain - - - 1.86e-237 741.0
REGS2_k127_1160424_6 PFAM glycoside hydrolase family 1 K05350 - 3.2.1.21 8.731e-232 726.0
REGS2_k127_1160424_7 Receptor family ligand binding region - - - 4.095e-226 715.0
REGS2_k127_1160424_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 559.0
REGS2_k127_1160424_9 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 512.0
REGS2_k127_1169667_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 388.0
REGS2_k127_1202816_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
REGS2_k127_1202816_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000004618 212.0
REGS2_k127_1202816_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000001705 186.0
REGS2_k127_1202816_3 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000005806 185.0
REGS2_k127_1213950_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 348.0
REGS2_k127_1222251_0 GTP-binding protein TypA K06207 - - 2.768e-240 758.0
REGS2_k127_1222251_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.476e-227 720.0
REGS2_k127_1222251_2 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 362.0
REGS2_k127_1222251_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000006842 137.0
REGS2_k127_1222251_4 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000006229 114.0
REGS2_k127_1222251_5 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.0000000000000000000000002353 109.0
REGS2_k127_1222251_6 Rieske [2Fe-2S] domain K03886 - - 0.0000000000000000000013 101.0
REGS2_k127_1222251_7 HEAT repeats - - - 0.00000000000008249 83.0
REGS2_k127_1222251_8 Putative zinc-finger - - - 0.0007674 51.0
REGS2_k127_1248436_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.94e-272 849.0
REGS2_k127_1248436_1 homoserine transmembrane transporter activity K06600,K06895 - - 0.000000000000000000000000000000000003257 145.0
REGS2_k127_1248436_2 - - - - 0.000000000000000002562 94.0
REGS2_k127_1248436_3 response regulator - - - 0.000000000000003463 81.0
REGS2_k127_1255309_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 525.0
REGS2_k127_1255309_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000724 81.0
REGS2_k127_1255309_2 Periplasmic or secreted lipoprotein - - - 0.00000000000000812 85.0
REGS2_k127_1255309_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000007863 65.0
REGS2_k127_128696_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 609.0
REGS2_k127_128696_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 426.0
REGS2_k127_128696_2 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
REGS2_k127_1312315_0 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 566.0
REGS2_k127_1312315_1 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 317.0
REGS2_k127_1312315_2 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001251 281.0
REGS2_k127_1312315_3 Cysteine-rich domain K18928 - - 0.00000000000000000000002995 101.0
REGS2_k127_1325706_0 PFAM Type II secretion system protein E K02652 - - 4.037e-230 726.0
REGS2_k127_1325706_1 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 504.0
REGS2_k127_1325706_10 PFAM Fimbrial assembly family protein K02663 - - 0.000001497 60.0
REGS2_k127_1325706_11 - - - - 0.00004899 53.0
REGS2_k127_1325706_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 341.0
REGS2_k127_1325706_3 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 310.0
REGS2_k127_1325706_4 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 309.0
REGS2_k127_1325706_5 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000002805 178.0
REGS2_k127_1325706_6 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.00000000000000000000000000000000000001699 146.0
REGS2_k127_1325706_7 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000002321 145.0
REGS2_k127_1325706_9 Pilus assembly protein K02662 - - 0.0000000000000006066 89.0
REGS2_k127_1395828_0 Domain of unknown function (DUF5117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 368.0
REGS2_k127_1395828_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
REGS2_k127_1420138_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 477.0
REGS2_k127_1420138_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 327.0
REGS2_k127_1431419_0 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 521.0
REGS2_k127_1431419_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 409.0
REGS2_k127_1431419_10 S-layer homology domain - - - 0.0009045 52.0
REGS2_k127_1431419_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 396.0
REGS2_k127_1431419_3 aromatic amino acid beta-eliminating lyase threonine aldolase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 380.0
REGS2_k127_1431419_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000001718 216.0
REGS2_k127_1431419_5 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000002774 192.0
REGS2_k127_1431419_6 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000001587 160.0
REGS2_k127_1431419_7 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000003648 142.0
REGS2_k127_1431419_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000002794 109.0
REGS2_k127_1431419_9 Methyltransferase domain - - - 0.00006674 53.0
REGS2_k127_1567904_0 Phosphoesterase family - - - 3.245e-225 726.0
REGS2_k127_1567904_1 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 4.265e-214 685.0
REGS2_k127_1567904_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 398.0
REGS2_k127_1567904_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000006246 107.0
REGS2_k127_1567904_4 Helix-turn-helix domain - - - 0.00002049 55.0
REGS2_k127_160568_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K04108 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 470.0
REGS2_k127_1643518_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 409.0
REGS2_k127_1643518_1 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000001313 89.0
REGS2_k127_1643518_2 DinB superfamily - - - 0.000000000002438 66.0
REGS2_k127_1643518_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0006963 48.0
REGS2_k127_165212_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007835 273.0
REGS2_k127_165212_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000003096 207.0
REGS2_k127_165212_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000007031 191.0
REGS2_k127_165212_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000775 166.0
REGS2_k127_165212_4 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000005071 137.0
REGS2_k127_165212_5 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000004916 96.0
REGS2_k127_165212_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000192 75.0
REGS2_k127_1668963_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002882 259.0
REGS2_k127_1668963_1 Stage II sporulation protein E - - - 0.000000000000000000000000000000000000000000000000000000003957 207.0
REGS2_k127_1737199_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1239.0
REGS2_k127_1737199_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 429.0
REGS2_k127_1737199_2 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002019 313.0
REGS2_k127_1737199_3 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000001567 236.0
REGS2_k127_1737199_4 His Kinase A (phosphoacceptor) domain - - - 0.00003625 55.0
REGS2_k127_1740288_0 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 425.0
REGS2_k127_1740288_1 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000000000000000000008634 184.0
REGS2_k127_1743136_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 611.0
REGS2_k127_1743136_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 420.0
REGS2_k127_1743136_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 385.0
REGS2_k127_1743136_3 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 326.0
REGS2_k127_1743136_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009833 265.0
REGS2_k127_1743136_5 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000001514 201.0
REGS2_k127_1743136_6 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000008002 156.0
REGS2_k127_1743136_7 efflux transmembrane transporter activity - - - 0.000000000000000001491 86.0
REGS2_k127_1753146_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 384.0
REGS2_k127_1753146_1 smart pdz dhr glgf K04771 - 3.4.21.107 0.0000000000000000000000001041 123.0
REGS2_k127_1762799_0 Involved in the tonB-independent uptake of proteins - - - 1.156e-255 807.0
REGS2_k127_1762799_1 Beta-lactamase - - - 3.872e-230 737.0
REGS2_k127_1762799_2 Insulinase (Peptidase family M16) K07263 - - 3.78e-222 726.0
REGS2_k127_1762799_3 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000838 150.0
REGS2_k127_1762799_4 FR47-like protein - - - 0.0000000000000000000000000000000000001451 147.0
REGS2_k127_1762799_5 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.00000000000000000000000000000001447 134.0
REGS2_k127_1762799_6 extracellular polysaccharide biosynthetic process K13582 - - 0.00000000000000000000000000005742 129.0
REGS2_k127_1762799_7 Dodecin K09165 - - 0.0000000000000000001545 90.0
REGS2_k127_1762799_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000001024 83.0
REGS2_k127_1762799_9 Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000004836 58.0
REGS2_k127_177888_0 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 413.0
REGS2_k127_177888_1 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 379.0
REGS2_k127_177888_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 333.0
REGS2_k127_177888_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002516 267.0
REGS2_k127_177888_4 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
REGS2_k127_177888_5 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000003621 207.0
REGS2_k127_177888_6 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.00000001973 62.0
REGS2_k127_1786546_0 phosphorelay sensor kinase activity K02478,K07704 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000007265 154.0
REGS2_k127_1793233_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000004159 171.0
REGS2_k127_1793233_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000009167 95.0
REGS2_k127_1793233_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000288 61.0
REGS2_k127_1807202_0 Belongs to the peptidase M16 family K07263 - - 4.406e-197 649.0
REGS2_k127_1807202_1 Transposase IS200 like K07491 - - 0.000000000000000000000005605 104.0
REGS2_k127_1812536_0 LUD domain K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 441.0
REGS2_k127_1812536_1 Cysteine-rich domain K18928 - - 0.00000000000000000000000003529 109.0
REGS2_k127_1812536_2 LUD domain K00782 - - 0.000000000000000002656 100.0
REGS2_k127_1812536_3 Type IV secretory pathway, VirJ component - - - 0.000000003717 58.0
REGS2_k127_1815829_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1131.0
REGS2_k127_1815829_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000004109 269.0
REGS2_k127_1815829_10 - - - - 0.000005772 51.0
REGS2_k127_1815829_2 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000005392 235.0
REGS2_k127_1815829_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000101 211.0
REGS2_k127_1815829_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000001194 167.0
REGS2_k127_1815829_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000005673 111.0
REGS2_k127_1815829_6 - - - - 0.000000000000000001399 92.0
REGS2_k127_1815829_7 transposition K07483,K07497 - - 0.0000000000000002269 78.0
REGS2_k127_1815829_8 - - - - 0.000000000001834 79.0
REGS2_k127_1815829_9 PBS lyase HEAT-like repeat - - - 0.0000004915 62.0
REGS2_k127_1820473_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.0 1732.0
REGS2_k127_1820473_1 hydrolase family 20, catalytic K12373 - 3.2.1.52 0.000000000000000000004757 95.0
REGS2_k127_1833181_0 PFAM Radical SAM - - - 1.353e-223 705.0
REGS2_k127_1833181_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000001066 181.0
REGS2_k127_1833181_2 - - - - 0.00000000000000000000000000000000001675 152.0
REGS2_k127_1833181_3 negative regulation of transcription, DNA-templated - - - 0.000000000001937 69.0
REGS2_k127_1838558_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 563.0
REGS2_k127_1838558_1 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 409.0
REGS2_k127_1838558_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 401.0
REGS2_k127_1838558_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000004708 166.0
REGS2_k127_1838558_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000001587 90.0
REGS2_k127_1841113_0 methyltransferase activity K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000125 206.0
REGS2_k127_1841113_1 Rubrerythrin K22336 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000002083 198.0
REGS2_k127_1841113_2 - - - - 0.000000000000000000000000000000000000000000007698 168.0
REGS2_k127_1841113_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000001125 164.0
REGS2_k127_1841113_4 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000000000002259 154.0
REGS2_k127_1844410_0 MacB-like periplasmic core domain - - - 2.332e-210 679.0
REGS2_k127_1851914_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0 1126.0
REGS2_k127_1851914_1 cellulose binding - - - 0.0 1119.0
REGS2_k127_1851914_2 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 6.427e-250 779.0
REGS2_k127_1851914_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 526.0
REGS2_k127_1851914_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 521.0
REGS2_k127_1851914_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000002534 178.0
REGS2_k127_1851914_6 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.000000000000000000000001615 114.0
REGS2_k127_1851914_7 amine dehydrogenase activity - - - 0.0000005212 62.0
REGS2_k127_1868608_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 605.0
REGS2_k127_1868608_1 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000000000000002594 146.0
REGS2_k127_1868608_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000004624 134.0
REGS2_k127_1868608_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000006465 131.0
REGS2_k127_1868608_4 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000003117 130.0
REGS2_k127_1874329_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.088e-227 735.0
REGS2_k127_1874329_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 478.0
REGS2_k127_1874329_10 DinB superfamily - - - 0.000000000000000000006683 96.0
REGS2_k127_1874329_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 441.0
REGS2_k127_1874329_3 - K00262 - 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 415.0
REGS2_k127_1874329_4 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001649 301.0
REGS2_k127_1874329_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000744 287.0
REGS2_k127_1874329_6 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005698 282.0
REGS2_k127_1874329_7 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000001017 211.0
REGS2_k127_1874329_8 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000004336 183.0
REGS2_k127_1879671_0 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 539.0
REGS2_k127_1879671_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 517.0
REGS2_k127_1879671_2 protease-associated PA domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
REGS2_k127_1879671_3 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 418.0
REGS2_k127_1879671_4 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 369.0
REGS2_k127_1879671_5 Trehalose utilisation K09992 - - 0.00000000000000000000000000000008419 139.0
REGS2_k127_1879671_6 DinB family - - - 0.000000000000000000000000000000146 141.0
REGS2_k127_1879671_7 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000893 47.0
REGS2_k127_1882175_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 5.282e-239 756.0
REGS2_k127_1882175_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 9.329e-237 740.0
REGS2_k127_1882175_2 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 490.0
REGS2_k127_1882175_3 glycerol channel activity K09876,K09877,K09886,K10404 GO:0002376,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006833,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008643,GO:0009605,GO:0009607,GO:0009617,GO:0015250,GO:0015267,GO:0015318,GO:0015791,GO:0015793,GO:0015850,GO:0016020,GO:0016323,GO:0022803,GO:0022838,GO:0022857,GO:0042044,GO:0042742,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0045087,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071702,GO:0071944,GO:0098542,GO:0098590 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 312.0
REGS2_k127_1882175_4 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 277.0
REGS2_k127_1882175_5 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000000000000001214 170.0
REGS2_k127_1882175_6 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000005569 136.0
REGS2_k127_1882175_7 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000002434 118.0
REGS2_k127_1882175_8 Carboxypeptidase regulatory-like domain - - - 0.0000000006944 63.0
REGS2_k127_1889585_0 4Fe-4S dicluster domain K00184 - - 0.0 1111.0
REGS2_k127_1889585_1 Polysulphide reductase, NrfD K00185 - - 8.522e-203 642.0
REGS2_k127_1889585_10 - - - - 0.0000000000000000106 90.0
REGS2_k127_1889585_2 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 548.0
REGS2_k127_1889585_3 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 363.0
REGS2_k127_1889585_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 370.0
REGS2_k127_1889585_5 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 319.0
REGS2_k127_1889585_6 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 302.0
REGS2_k127_1889585_7 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000001621 251.0
REGS2_k127_1889585_8 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
REGS2_k127_1889585_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000005655 229.0
REGS2_k127_1892948_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 548.0
REGS2_k127_1892948_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 307.0
REGS2_k127_1892948_2 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000255 137.0
REGS2_k127_1903962_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 306.0
REGS2_k127_1903962_1 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002615 246.0
REGS2_k127_1903962_2 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000831 155.0
REGS2_k127_1903962_3 AAA domain - - - 0.000000000000000000000000000000000001177 144.0
REGS2_k127_190622_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 544.0
REGS2_k127_190622_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 442.0
REGS2_k127_190622_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 451.0
REGS2_k127_190622_3 Belongs to the binding-protein-dependent transport system permease family K17214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001302 265.0
REGS2_k127_190622_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000007453 157.0
REGS2_k127_1923811_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.173e-248 779.0
REGS2_k127_1923811_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.879e-221 711.0
REGS2_k127_1923811_10 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007067 274.0
REGS2_k127_1923811_11 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002312 260.0
REGS2_k127_1923811_12 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000009427 247.0
REGS2_k127_1923811_13 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
REGS2_k127_1923811_14 Surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000002929 254.0
REGS2_k127_1923811_15 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000008139 237.0
REGS2_k127_1923811_16 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000009238 229.0
REGS2_k127_1923811_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000004569 151.0
REGS2_k127_1923811_18 response regulator - - - 0.00000000000000000000008196 108.0
REGS2_k127_1923811_19 Biotin-requiring enzyme - - - 0.0000000000000000009103 98.0
REGS2_k127_1923811_2 ABC transporter C-terminal domain K06158 - - 2.167e-199 643.0
REGS2_k127_1923811_20 Fibronectin type 3 domain - - - 0.00000000000000134 91.0
REGS2_k127_1923811_21 Helix-turn-helix domain - - - 0.000000001235 61.0
REGS2_k127_1923811_23 Anti-sigma-K factor rskA - - - 0.00005332 54.0
REGS2_k127_1923811_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 5.876e-199 630.0
REGS2_k127_1923811_4 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 521.0
REGS2_k127_1923811_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 514.0
REGS2_k127_1923811_6 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 437.0
REGS2_k127_1923811_7 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 328.0
REGS2_k127_1923811_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 291.0
REGS2_k127_1923811_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007891 313.0
REGS2_k127_1928611_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.579e-276 857.0
REGS2_k127_1935854_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 385.0
REGS2_k127_1935854_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000006426 74.0
REGS2_k127_1935854_2 Dehydrogenase K00074 - 1.1.1.157 0.00003487 47.0
REGS2_k127_1956121_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 5.092e-230 737.0
REGS2_k127_1956121_1 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 352.0
REGS2_k127_1956121_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 325.0
REGS2_k127_1956121_3 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 316.0
REGS2_k127_1956121_4 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000196 247.0
REGS2_k127_1956121_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004604 251.0
REGS2_k127_1956121_6 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000626 250.0
REGS2_k127_1956121_7 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000001439 157.0
REGS2_k127_1956121_8 bacterial OsmY and nodulation domain - - - 0.00000007842 62.0
REGS2_k127_1959776_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.75e-226 706.0
REGS2_k127_1959776_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.918e-196 619.0
REGS2_k127_1959776_2 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 438.0
REGS2_k127_1959776_3 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000002521 135.0
REGS2_k127_1966628_0 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 624.0
REGS2_k127_1966628_1 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 528.0
REGS2_k127_1966628_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 424.0
REGS2_k127_1966628_3 FR47-like protein - - - 0.00000000000000000000000000000000000000008066 156.0
REGS2_k127_1966628_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000003381 131.0
REGS2_k127_1966628_5 PFAM membrane protein of K08972 - - 0.000000000000000000000000001002 115.0
REGS2_k127_1966628_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000002609 59.0
REGS2_k127_1966628_7 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 0.0001746 44.0
REGS2_k127_1968266_0 Carboxyl transferase domain - - - 8.357e-233 735.0
REGS2_k127_1968266_1 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 550.0
REGS2_k127_1968266_2 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000849 276.0
REGS2_k127_1968266_3 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000003093 209.0
REGS2_k127_1968266_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001364 206.0
REGS2_k127_1968266_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000001016 171.0
REGS2_k127_1968266_6 - - - - 0.000000000000000000000000000000007901 132.0
REGS2_k127_197594_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000002324 146.0
REGS2_k127_197594_1 WHG domain - - - 0.00000000000000000000000000007062 124.0
REGS2_k127_1978098_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.775e-285 887.0
REGS2_k127_1978098_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 369.0
REGS2_k127_1978098_2 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 295.0
REGS2_k127_1978098_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000006036 158.0
REGS2_k127_1978098_4 von Willebrand factor, type A - - - 0.0000000000000000000000000000001013 136.0
REGS2_k127_1978098_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000001162 131.0
REGS2_k127_1978098_7 Patatin-like phospholipase K07001 - - 0.0005469 53.0
REGS2_k127_1983348_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.304e-267 833.0
REGS2_k127_1983348_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.228e-251 789.0
REGS2_k127_1983348_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 3.104e-197 623.0
REGS2_k127_1983348_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 449.0
REGS2_k127_1983348_4 Ribosomal RNA adenine dimethylase K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000007372 235.0
REGS2_k127_1983348_5 Succinate dehydrogenase fumarate reductase Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.0000000000002633 70.0
REGS2_k127_1997726_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001442 258.0
REGS2_k127_2027007_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1369.0
REGS2_k127_2027007_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 434.0
REGS2_k127_2027007_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 417.0
REGS2_k127_2027007_3 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 327.0
REGS2_k127_2027007_4 PFAM PEGA domain - - - 0.000000000000000129 94.0
REGS2_k127_2027007_5 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0000000000000006818 92.0
REGS2_k127_2123830_0 elongation factor G K02355 - - 8.415e-225 717.0
REGS2_k127_2123830_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 470.0
REGS2_k127_2123830_2 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000004711 136.0
REGS2_k127_2123830_3 Helix-hairpin-helix motif - - - 0.0000000000000000001714 94.0
REGS2_k127_2123830_4 FtsX-like permease family K02004 - - 0.0000000000000004412 79.0
REGS2_k127_2123830_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000002446 67.0
REGS2_k127_2163194_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 397.0
REGS2_k127_2163194_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 390.0
REGS2_k127_2163194_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000006465 171.0
REGS2_k127_2167794_0 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 580.0
REGS2_k127_2167794_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 434.0
REGS2_k127_2167794_2 PFAM Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 367.0
REGS2_k127_2167794_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000899 174.0
REGS2_k127_2167794_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000001765 109.0
REGS2_k127_2167794_5 Lysin motif - - - 0.00000000000000000000007964 104.0
REGS2_k127_2167794_6 Cupin domain K01607 - 4.1.1.44 0.000000000000000001814 100.0
REGS2_k127_217127_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 570.0
REGS2_k127_217127_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 478.0
REGS2_k127_217127_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000005503 124.0
REGS2_k127_217127_11 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000009448 107.0
REGS2_k127_217127_12 von Willebrand factor, type A K07114 - - 0.0000000005008 70.0
REGS2_k127_217127_2 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 463.0
REGS2_k127_217127_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 373.0
REGS2_k127_217127_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 364.0
REGS2_k127_217127_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000001745 248.0
REGS2_k127_217127_6 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000006454 178.0
REGS2_k127_217127_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000009693 163.0
REGS2_k127_217127_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000005845 152.0
REGS2_k127_217127_9 Cytochrome C assembly protein - - - 0.000000000000000000000000000000005698 139.0
REGS2_k127_2172549_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.278e-306 965.0
REGS2_k127_2172549_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 363.0
REGS2_k127_2248763_0 Dienelactone hydrolase family - - - 1.512e-238 754.0
REGS2_k127_2248763_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 512.0
REGS2_k127_2248763_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000019 194.0
REGS2_k127_2248763_11 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000000000000000000000000002612 130.0
REGS2_k127_2248763_12 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000001531 121.0
REGS2_k127_2248763_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000185 115.0
REGS2_k127_2248763_14 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.0000000000000000000172 103.0
REGS2_k127_2248763_2 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 391.0
REGS2_k127_2248763_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 371.0
REGS2_k127_2248763_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 346.0
REGS2_k127_2248763_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 337.0
REGS2_k127_2248763_6 aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 327.0
REGS2_k127_2248763_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
REGS2_k127_2248763_8 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000003144 229.0
REGS2_k127_2248763_9 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000008924 216.0
REGS2_k127_2253886_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 4.198e-263 827.0
REGS2_k127_2253886_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 526.0
REGS2_k127_2253886_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 448.0
REGS2_k127_2253886_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 351.0
REGS2_k127_2253886_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 340.0
REGS2_k127_2253886_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000002057 95.0
REGS2_k127_2277560_0 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 5.603e-197 632.0
REGS2_k127_2277560_1 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 419.0
REGS2_k127_2277560_2 transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001913 285.0
REGS2_k127_2277560_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000004751 262.0
REGS2_k127_2277560_4 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000004254 217.0
REGS2_k127_2277560_5 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000003262 188.0
REGS2_k127_2277560_6 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000002545 113.0
REGS2_k127_2309276_0 Acetolactate synthase K00156,K01652 - 1.2.5.1,2.2.1.6 4.201e-244 769.0
REGS2_k127_2309276_1 Proposed role in polysaccahride synthesis K07077 - - 6.751e-216 683.0
REGS2_k127_2309276_2 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 455.0
REGS2_k127_2309276_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008897 285.0
REGS2_k127_2309276_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000009322 197.0
REGS2_k127_2309276_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000155 169.0
REGS2_k127_2309276_6 RibD C-terminal domain - - - 0.0000000000000000000000000001643 118.0
REGS2_k127_2309276_7 - - - - 0.000000000000000000000000009044 126.0
REGS2_k127_2309276_8 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000002888 118.0
REGS2_k127_2318491_0 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000003058 161.0
REGS2_k127_2318491_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000003736 102.0
REGS2_k127_2359780_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
REGS2_k127_2359780_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 469.0
REGS2_k127_2359780_10 Preprotein translocase SecG subunit K03075 - - 0.00000000003087 70.0
REGS2_k127_2359780_11 Belongs to the ompA family - - - 0.000001607 55.0
REGS2_k127_2359780_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 317.0
REGS2_k127_2359780_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 274.0
REGS2_k127_2359780_4 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000001845 259.0
REGS2_k127_2359780_5 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000381 197.0
REGS2_k127_2359780_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000004635 199.0
REGS2_k127_2359780_7 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000004971 199.0
REGS2_k127_2359780_8 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000009186 192.0
REGS2_k127_2359780_9 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000445 93.0
REGS2_k127_2483791_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 416.0
REGS2_k127_2483791_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 396.0
REGS2_k127_2483791_2 - - - - 0.00000000000000000000259 109.0
REGS2_k127_2483791_3 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.0000000000000003762 84.0
REGS2_k127_2483791_4 Type II transport protein GspH K08084 - - 0.00001081 55.0
REGS2_k127_2553761_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.912e-238 747.0
REGS2_k127_2553761_1 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 581.0
REGS2_k127_2553761_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 345.0
REGS2_k127_2553761_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 328.0
REGS2_k127_2553761_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 295.0
REGS2_k127_2553761_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000001016 165.0
REGS2_k127_2553761_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000001845 115.0
REGS2_k127_2553761_7 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000006415 107.0
REGS2_k127_2588856_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 454.0
REGS2_k127_2588856_1 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002438 265.0
REGS2_k127_2588856_2 Histidine kinase - - - 0.00000000000005671 79.0
REGS2_k127_2588856_3 oxidoreductase activity - - - 0.0002554 50.0
REGS2_k127_2589479_0 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 419.0
REGS2_k127_2589479_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 406.0
REGS2_k127_2589479_10 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 252.0
REGS2_k127_2589479_11 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000889 188.0
REGS2_k127_2589479_12 - - - - 0.0000000000000000000001777 109.0
REGS2_k127_2589479_13 Thioredoxin domain - - - 0.00000000000002106 85.0
REGS2_k127_2589479_15 - - - - 0.0000008183 57.0
REGS2_k127_2589479_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 377.0
REGS2_k127_2589479_3 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 353.0
REGS2_k127_2589479_4 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 343.0
REGS2_k127_2589479_5 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 324.0
REGS2_k127_2589479_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 312.0
REGS2_k127_2589479_7 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 298.0
REGS2_k127_2589479_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003822 264.0
REGS2_k127_2589479_9 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000777 265.0
REGS2_k127_2594269_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 595.0
REGS2_k127_2594269_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 417.0
REGS2_k127_2594269_2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 310.0
REGS2_k127_2594269_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 307.0
REGS2_k127_2594269_4 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009261 275.0
REGS2_k127_2594269_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000000000000000000000000000000002452 224.0
REGS2_k127_2594269_6 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000124 88.0
REGS2_k127_2594269_7 unfolded protein binding K06142 - - 0.0000001528 55.0
REGS2_k127_2608867_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 560.0
REGS2_k127_2608867_1 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000006801 160.0
REGS2_k127_2618516_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.081e-287 903.0
REGS2_k127_2618516_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657 3.3.1.1 5.853e-213 672.0
REGS2_k127_2618516_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 611.0
REGS2_k127_2618516_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 326.0
REGS2_k127_2618516_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006008 308.0
REGS2_k127_2618516_5 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000149 137.0
REGS2_k127_2620078_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1193.0
REGS2_k127_2620078_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 364.0
REGS2_k127_2620078_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000188 212.0
REGS2_k127_2620078_3 recA bacterial DNA recombination protein - - - 0.00000000000000000000007232 108.0
REGS2_k127_2620078_4 Belongs to the UPF0234 family K09767 - - 0.0000001789 52.0
REGS2_k127_2643303_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1087.0
REGS2_k127_2643303_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 2.224e-205 657.0
REGS2_k127_2643303_10 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000161 215.0
REGS2_k127_2643303_11 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000001368 135.0
REGS2_k127_2643303_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000002801 113.0
REGS2_k127_2643303_13 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000002773 106.0
REGS2_k127_2643303_14 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000002601 81.0
REGS2_k127_2643303_2 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 518.0
REGS2_k127_2643303_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 479.0
REGS2_k127_2643303_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 443.0
REGS2_k127_2643303_5 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 411.0
REGS2_k127_2643303_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 382.0
REGS2_k127_2643303_7 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 374.0
REGS2_k127_2643303_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 312.0
REGS2_k127_2643303_9 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000002514 231.0
REGS2_k127_2649492_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000574 261.0
REGS2_k127_2649492_1 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K01992,K04567,K10716 - 6.1.1.6 0.000000000000000000000000000004488 124.0
REGS2_k127_2649492_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000002514 104.0
REGS2_k127_2664397_0 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 307.0
REGS2_k127_2664397_1 PFAM SAF domain K02279 - - 0.00000000000000000000000000000000000000000000000001158 190.0
REGS2_k127_2664397_2 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.0000000000003492 78.0
REGS2_k127_2664397_3 TadE-like protein - - - 0.0000002412 62.0
REGS2_k127_2664397_4 Putative Tad-like Flp pilus-assembly - - - 0.0000006101 59.0
REGS2_k127_2664397_5 Flp/Fap pilin component K02651 - - 0.0000926 49.0
REGS2_k127_2664397_6 Flp Fap pilin component K02651 - - 0.0002746 48.0
REGS2_k127_2676868_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1077.0
REGS2_k127_2676868_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 9.642e-272 858.0
REGS2_k127_2676868_2 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 460.0
REGS2_k127_2676868_3 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007572 282.0
REGS2_k127_2676868_4 CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008661 259.0
REGS2_k127_2676868_5 - - - - 0.00000000000000000000000000000000000000000000000000008427 197.0
REGS2_k127_2676868_6 Peptidase M48 K06013 - 3.4.24.84 0.00004165 46.0
REGS2_k127_2690471_0 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 508.0
REGS2_k127_2690471_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 345.0
REGS2_k127_2690471_2 Domain of unknown function DUF302 - - - 0.00000000000000000000001062 103.0
REGS2_k127_2690471_3 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000002632 78.0
REGS2_k127_2690471_4 FeoA K04758 - - 0.0000003835 57.0
REGS2_k127_2692204_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004222 270.0
REGS2_k127_2692204_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000506 189.0
REGS2_k127_2692204_2 outer membrane autotransporter barrel domain protein - - - 0.00001434 55.0
REGS2_k127_2692204_3 Glycosyl hydrolase family 63 C-terminal domain - - - 0.00007977 49.0
REGS2_k127_2694383_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
REGS2_k127_2694383_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008514 276.0
REGS2_k127_2694383_2 PFAM secretion protein HlyD family protein K02005 - - 0.00000000000000000000000000005855 133.0
REGS2_k127_2702719_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 444.0
REGS2_k127_2702719_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 325.0
REGS2_k127_2702719_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 305.0
REGS2_k127_2710864_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
REGS2_k127_2710864_1 response regulator, receiver K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000876 241.0
REGS2_k127_2710864_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001945 244.0
REGS2_k127_2710864_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000005487 224.0
REGS2_k127_2710864_4 Amino acid permease - - - 0.000000000000000000000000000000001879 132.0
REGS2_k127_2720251_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 605.0
REGS2_k127_2720251_1 domain, Protein - - - 0.0000000000000000000000000000000000036 156.0
REGS2_k127_2720251_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000002418 104.0
REGS2_k127_2720251_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000002151 64.0
REGS2_k127_273335_0 Thiolase, C-terminal domain K02615 - 2.3.1.174,2.3.1.223 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 533.0
REGS2_k127_273335_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 434.0
REGS2_k127_273335_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000001489 125.0
REGS2_k127_273335_3 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.0000000000000001585 80.0
REGS2_k127_27390_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 562.0
REGS2_k127_27390_1 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 506.0
REGS2_k127_27390_10 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000005115 165.0
REGS2_k127_27390_11 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000001318 151.0
REGS2_k127_27390_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000007868 153.0
REGS2_k127_27390_13 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000002801 113.0
REGS2_k127_27390_14 Oxidoreductase FAD-binding domain - - - 0.000000000000000005384 93.0
REGS2_k127_27390_15 - - - - 0.00000000000000175 84.0
REGS2_k127_27390_16 bacterial OsmY and nodulation domain - - - 0.0000000000001911 74.0
REGS2_k127_27390_17 - - - - 0.000000000001544 79.0
REGS2_k127_27390_18 - - - - 0.000004676 57.0
REGS2_k127_27390_19 - - - - 0.000009252 51.0
REGS2_k127_27390_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 427.0
REGS2_k127_27390_20 - - - - 0.00008264 50.0
REGS2_k127_27390_3 Deoxyhypusine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 396.0
REGS2_k127_27390_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 342.0
REGS2_k127_27390_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 309.0
REGS2_k127_27390_6 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008202 283.0
REGS2_k127_27390_7 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000002273 263.0
REGS2_k127_27390_8 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000005836 254.0
REGS2_k127_27390_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000001084 188.0
REGS2_k127_2745123_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 610.0
REGS2_k127_2745123_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 578.0
REGS2_k127_2745123_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 522.0
REGS2_k127_2745123_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 387.0
REGS2_k127_2745123_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 382.0
REGS2_k127_2745123_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000017 254.0
REGS2_k127_2745123_6 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007554 243.0
REGS2_k127_2745123_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000004186 192.0
REGS2_k127_2745123_8 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000001363 126.0
REGS2_k127_2745123_9 regulatory protein, MerR - - - 0.0000000000000001439 89.0
REGS2_k127_2762304_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 397.0
REGS2_k127_2768389_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 6.205e-209 660.0
REGS2_k127_2768389_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000001919 74.0
REGS2_k127_2768389_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000004318 78.0
REGS2_k127_2783824_0 metallocarboxypeptidase activity K14054 - - 0.0 1224.0
REGS2_k127_2783824_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000003309 192.0
REGS2_k127_2783824_2 arylsulfatase A - - - 0.00000000000000000000000000000005328 132.0
REGS2_k127_2787382_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.192e-282 878.0
REGS2_k127_2787382_1 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 593.0
REGS2_k127_2787382_10 Dna alkylation repair - - - 0.00000000000000000000000000000000000000000001436 172.0
REGS2_k127_2787382_11 cyclohydrolase K01746 - 4.3.1.4 0.00000000000000000000000001705 116.0
REGS2_k127_2787382_12 PFAM DivIVA family protein K04074 - - 0.00000000000000000856 91.0
REGS2_k127_2787382_13 Belongs to the UPF0235 family K09131 - - 0.000000000004664 71.0
REGS2_k127_2787382_14 SMART Tetratricopeptide domain protein - - - 0.000000002186 68.0
REGS2_k127_2787382_2 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 548.0
REGS2_k127_2787382_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 454.0
REGS2_k127_2787382_4 Methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 388.0
REGS2_k127_2787382_5 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 370.0
REGS2_k127_2787382_6 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000002569 237.0
REGS2_k127_2787382_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000002959 219.0
REGS2_k127_2787382_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000005319 224.0
REGS2_k127_2787382_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000001127 206.0
REGS2_k127_2792150_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 331.0
REGS2_k127_2792150_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000002154 204.0
REGS2_k127_2792150_2 Oligopeptidase K01284 - 3.4.15.5 0.0000000000000000000002297 99.0
REGS2_k127_2792150_3 - - - - 0.000001933 52.0
REGS2_k127_2792420_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 508.0
REGS2_k127_2792420_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 476.0
REGS2_k127_2792420_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 368.0
REGS2_k127_2792420_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004163 254.0
REGS2_k127_2792420_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000001331 188.0
REGS2_k127_2792420_5 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000001297 147.0
REGS2_k127_2792420_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000003678 139.0
REGS2_k127_2792420_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000002927 120.0
REGS2_k127_2792420_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000003801 111.0
REGS2_k127_2792420_9 NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000007392 95.0
REGS2_k127_2809408_0 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 340.0
REGS2_k127_2809408_1 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 323.0
REGS2_k127_28403_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.769e-315 987.0
REGS2_k127_28403_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 574.0
REGS2_k127_28403_10 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000004254 123.0
REGS2_k127_28403_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000009575 116.0
REGS2_k127_28403_12 Lipopolysaccharide-assembly - - - 0.000000000000000000000193 104.0
REGS2_k127_28403_13 Ribosomal L32p protein family K02911 - - 0.00000000000000000003814 93.0
REGS2_k127_28403_14 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000005874 74.0
REGS2_k127_28403_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 492.0
REGS2_k127_28403_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 335.0
REGS2_k127_28403_4 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 329.0
REGS2_k127_28403_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 326.0
REGS2_k127_28403_6 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002002 281.0
REGS2_k127_28403_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002218 274.0
REGS2_k127_28403_8 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001298 273.0
REGS2_k127_28403_9 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000008048 159.0
REGS2_k127_2854048_0 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000001365 164.0
REGS2_k127_2854048_1 Sigma factor PP2C-like phosphatases - - - 0.0002626 45.0
REGS2_k127_2863655_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 617.0
REGS2_k127_2863655_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 569.0
REGS2_k127_2863655_10 histone methyltransferase activity (H3-K4 specific) K09186,K09188,K22197 - 2.1.1.43 0.00000000000000000000000000002664 123.0
REGS2_k127_2863655_11 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000002362 86.0
REGS2_k127_2863655_12 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000001518 70.0
REGS2_k127_2863655_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 553.0
REGS2_k127_2863655_3 UDP binding domain K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 516.0
REGS2_k127_2863655_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 306.0
REGS2_k127_2863655_5 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 300.0
REGS2_k127_2863655_6 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003689 305.0
REGS2_k127_2863655_7 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000003032 212.0
REGS2_k127_2863655_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000001408 207.0
REGS2_k127_2863655_9 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000001688 153.0
REGS2_k127_2867435_0 Fungalysin metallopeptidase (M36) - - - 3.487e-217 709.0
REGS2_k127_2867435_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 460.0
REGS2_k127_2867435_2 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 310.0
REGS2_k127_2867435_4 Histidine kinase - - - 0.0002447 49.0
REGS2_k127_2867634_0 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000009827 217.0
REGS2_k127_2867634_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000003942 186.0
REGS2_k127_2867634_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000002472 135.0
REGS2_k127_2885787_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008966 289.0
REGS2_k127_2892983_0 serine-type peptidase activity - - - 0.0 1156.0
REGS2_k127_2892983_1 MacB-like periplasmic core domain - - - 0.0 1020.0
REGS2_k127_2892983_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003193 258.0
REGS2_k127_2892983_3 CoA binding domain K06929 - - 0.00000000000000000000000000000001035 137.0
REGS2_k127_2892983_4 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.00000000000000001449 82.0
REGS2_k127_2902018_0 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 555.0
REGS2_k127_2902018_1 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 530.0
REGS2_k127_2902018_2 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 377.0
REGS2_k127_2902018_3 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 334.0
REGS2_k127_2902018_4 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000003283 155.0
REGS2_k127_2902018_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000002722 127.0
REGS2_k127_294675_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 349.0
REGS2_k127_294675_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000001293 228.0
REGS2_k127_294675_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000001673 193.0
REGS2_k127_294675_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000005073 169.0
REGS2_k127_294675_4 OmpA family K03640 - - 0.000000000000000000000000000000000000007809 151.0
REGS2_k127_294675_5 oligosaccharyl transferase activity - - - 0.00000000000000000000000000001136 136.0
REGS2_k127_3014533_0 MacB-like periplasmic core domain - - - 1.296e-288 919.0
REGS2_k127_3014533_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
REGS2_k127_3014533_2 translation initiation factor activity K06996 - - 0.00003207 54.0
REGS2_k127_304618_0 3-hydroxyacyl-CoA dehydrogenase domain protein K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 369.0
REGS2_k127_304618_1 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000004315 117.0
REGS2_k127_3046370_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 7.452e-269 845.0
REGS2_k127_3046370_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.271e-236 765.0
REGS2_k127_3046370_10 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000007782 89.0
REGS2_k127_3046370_11 Iron-sulfur cluster-binding domain - - - 0.000000000000001695 91.0
REGS2_k127_3046370_12 - - - - 0.00000000003634 76.0
REGS2_k127_3046370_13 Radical SAM domain protein - - - 0.0000000008535 72.0
REGS2_k127_3046370_14 Cupredoxin-like domain K00376 - 1.7.2.4 0.00000000478 62.0
REGS2_k127_3046370_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 458.0
REGS2_k127_3046370_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 416.0
REGS2_k127_3046370_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000006481 233.0
REGS2_k127_3046370_5 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000006784 229.0
REGS2_k127_3046370_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000003712 141.0
REGS2_k127_3046370_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000406 134.0
REGS2_k127_3046370_8 integral membrane protein - - - 0.00000000000000000000000000001139 134.0
REGS2_k127_3046370_9 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000003027 124.0
REGS2_k127_3069691_0 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000006262 204.0
REGS2_k127_3069691_1 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000002372 74.0
REGS2_k127_3075731_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1218.0
REGS2_k127_3075731_1 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 520.0
REGS2_k127_3075731_2 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 326.0
REGS2_k127_3075731_3 hyperosmotic response - - - 0.000000000000000000003348 102.0
REGS2_k127_3075731_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000008402 61.0
REGS2_k127_3075731_5 CAAX amino terminal protease family - - - 0.0003048 51.0
REGS2_k127_3095242_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 454.0
REGS2_k127_3095242_1 ADP binding K08282,K13419 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.11.1 0.00000001025 66.0
REGS2_k127_311615_0 PhoQ Sensor - - - 0.00000000000000000000000000000000004965 151.0
REGS2_k127_311615_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000005186 66.0
REGS2_k127_3120327_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 485.0
REGS2_k127_3120327_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 438.0
REGS2_k127_3120327_2 Transcriptional regulator - - - 0.000000000000003135 78.0
REGS2_k127_31826_0 TIGRFAM amidase, hydantoinase carbamoylase K02083,K06016,K18151 - 3.5.1.116,3.5.1.6,3.5.1.87,3.5.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 547.0
REGS2_k127_31826_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004965 238.0
REGS2_k127_31826_2 - - - - 0.000000000000000000000000000000000000000000001676 175.0
REGS2_k127_31826_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000003231 172.0
REGS2_k127_31826_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000008686 141.0
REGS2_k127_31826_5 YjbR - - - 0.00000000000000000000000000000006064 128.0
REGS2_k127_31826_6 - - - - 0.0000000000000000006868 93.0
REGS2_k127_31826_7 SpoVT / AbrB like domain K07172 - - 0.00000000000000000119 91.0
REGS2_k127_31826_8 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000004557 65.0
REGS2_k127_31826_9 integral membrane protein - - - 0.000000000004629 68.0
REGS2_k127_3190234_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 2.709e-208 658.0
REGS2_k127_3190234_1 PFAM Disulphide bond formation protein DsbB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001466 284.0
REGS2_k127_3192314_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 597.0
REGS2_k127_3192314_1 Cyclic nucleotide-monophosphate binding domain K01420 - - 0.0000000000000000000000000000000000001468 151.0
REGS2_k127_3192314_2 amidohydrolase K03392 - 4.1.1.45 0.000000000000001984 76.0
REGS2_k127_3390446_0 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 364.0
REGS2_k127_3390446_1 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005929 267.0
REGS2_k127_3390446_2 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000001604 131.0
REGS2_k127_3390446_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000005716 96.0
REGS2_k127_3414137_0 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 342.0
REGS2_k127_3414137_1 glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001532 259.0
REGS2_k127_3414137_2 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001487 246.0
REGS2_k127_3414137_3 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
REGS2_k127_3414137_4 Universal stress protein family - - - 0.0000000000000000000000000000000000000006177 153.0
REGS2_k127_3452373_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 586.0
REGS2_k127_3452373_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 494.0
REGS2_k127_3452373_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 449.0
REGS2_k127_3452373_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 327.0
REGS2_k127_3452373_4 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003132 285.0
REGS2_k127_3452373_5 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000004883 225.0
REGS2_k127_3452373_6 Glycosyl hydrolase family 47 K01230,K10085 - 3.2.1.113 0.00000000000000000000000000000000000000000000000007862 181.0
REGS2_k127_3475064_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003589 263.0
REGS2_k127_3475064_1 receptor K02014 - - 0.000000000000000000000000001678 130.0
REGS2_k127_3486874_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 597.0
REGS2_k127_3486874_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000006624 194.0
REGS2_k127_3486874_2 Protein of unknown function (DUF1653) - - - 0.0003955 50.0
REGS2_k127_3496816_0 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000326 232.0
REGS2_k127_3496816_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000001172 233.0
REGS2_k127_3496816_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000814 201.0
REGS2_k127_3496816_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000005805 103.0
REGS2_k127_3497098_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000005478 216.0
REGS2_k127_3497098_1 solute binding protein K02035 - - 0.000001542 60.0
REGS2_k127_3502471_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.206e-258 833.0
REGS2_k127_3502471_1 Peptidase family M1 domain K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 517.0
REGS2_k127_3502471_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 366.0
REGS2_k127_3502471_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
REGS2_k127_3502471_4 PFAM GGDEF domain containing protein - - - 0.0001969 49.0
REGS2_k127_3512016_0 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
REGS2_k127_3512016_1 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000174 199.0
REGS2_k127_3513113_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.529e-269 841.0
REGS2_k127_3513113_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 499.0
REGS2_k127_3513113_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000003183 276.0
REGS2_k127_3513113_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000002056 267.0
REGS2_k127_3513113_12 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005996 263.0
REGS2_k127_3513113_13 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000009388 272.0
REGS2_k127_3513113_14 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004583 260.0
REGS2_k127_3513113_15 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005371 255.0
REGS2_k127_3513113_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000003504 227.0
REGS2_k127_3513113_17 Psort location CytoplasmicMembrane, score K01992 - - 0.000000000000000000000000000000000000000000000000007762 190.0
REGS2_k127_3513113_18 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000000006941 150.0
REGS2_k127_3513113_19 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000004657 162.0
REGS2_k127_3513113_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 414.0
REGS2_k127_3513113_20 Psort location Cytoplasmic, score K21903 - - 0.000000000000000000000000000003577 124.0
REGS2_k127_3513113_21 YbbR-like protein - - - 0.00000000000000000000000000005068 129.0
REGS2_k127_3513113_22 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000003104 116.0
REGS2_k127_3513113_23 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000008322 121.0
REGS2_k127_3513113_24 Tetratricopeptide repeat - - - 0.0000000000000000000000001856 113.0
REGS2_k127_3513113_25 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000008144 92.0
REGS2_k127_3513113_26 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000007159 74.0
REGS2_k127_3513113_27 Serine aminopeptidase, S33 - - - 0.00000002927 64.0
REGS2_k127_3513113_28 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.00000006098 57.0
REGS2_k127_3513113_29 - - - - 0.00000098 53.0
REGS2_k127_3513113_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 366.0
REGS2_k127_3513113_30 SMART TRASH domain protein - - - 0.00009637 49.0
REGS2_k127_3513113_4 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 348.0
REGS2_k127_3513113_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 330.0
REGS2_k127_3513113_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 303.0
REGS2_k127_3513113_7 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006682 288.0
REGS2_k127_3513113_8 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002309 280.0
REGS2_k127_3513113_9 Threonine alanine tRNA ligase second additional domain protein K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004548 287.0
REGS2_k127_351606_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 313.0
REGS2_k127_351606_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000008738 124.0
REGS2_k127_351606_2 Biotin-lipoyl like K02005 - - 0.000000000000000000002934 98.0
REGS2_k127_3526559_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 490.0
REGS2_k127_3526559_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 469.0
REGS2_k127_3526559_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000006812 103.0
REGS2_k127_3526559_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00007869 51.0
REGS2_k127_3528414_0 malic protein domain protein K00029 - 1.1.1.40 3.008e-285 896.0
REGS2_k127_3528414_1 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 9.673e-212 662.0
REGS2_k127_3528414_10 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 353.0
REGS2_k127_3528414_11 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 332.0
REGS2_k127_3528414_12 Outer membrane protein beta-barrel family K16087,K16092 - - 0.0000000000000000000000000003943 132.0
REGS2_k127_3528414_13 Belongs to the peptidase S33 family - - - 0.000000000000000000001348 106.0
REGS2_k127_3528414_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000002177 68.0
REGS2_k127_3528414_15 Protein conserved in bacteria K15539 - - 0.000000006051 66.0
REGS2_k127_3528414_2 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 4.662e-199 633.0
REGS2_k127_3528414_3 Belongs to the peptidase S8 family K13275 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 501.0
REGS2_k127_3528414_4 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 481.0
REGS2_k127_3528414_5 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 471.0
REGS2_k127_3528414_6 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 454.0
REGS2_k127_3528414_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 437.0
REGS2_k127_3528414_8 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 404.0
REGS2_k127_3528414_9 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 399.0
REGS2_k127_3539488_0 Tetratricopeptide repeat - - - 0.00000001077 68.0
REGS2_k127_3546810_0 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 336.0
REGS2_k127_3546810_1 O-methyltransferase - - - 0.000000000000000000000003305 110.0
REGS2_k127_3546810_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00003538 47.0
REGS2_k127_355302_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713,K07714 - - 0.000000000000000000000000000000001451 136.0
REGS2_k127_3580037_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 4.252e-249 785.0
REGS2_k127_3580037_1 Predicted membrane protein (DUF2339) - - - 4.131e-234 769.0
REGS2_k127_3580037_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 428.0
REGS2_k127_3580037_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 358.0
REGS2_k127_3580037_4 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001362 269.0
REGS2_k127_3585155_0 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 597.0
REGS2_k127_3585155_1 protease-associated PA domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 315.0
REGS2_k127_3585155_2 aldo keto reductase - - - 0.000000000000000000000000000000000000005185 159.0
REGS2_k127_3585155_3 - - - - 0.0000000000000000000000000000001709 130.0
REGS2_k127_3585155_4 amino acid K03294 - - 0.0000008214 53.0
REGS2_k127_359761_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.053e-230 729.0
REGS2_k127_359761_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006085 234.0
REGS2_k127_3607088_0 AcrB/AcrD/AcrF family K03296 - - 2.148e-238 779.0
REGS2_k127_3625708_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 469.0
REGS2_k127_3636836_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1077.0
REGS2_k127_3636836_1 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000000000000000000000000000000000000000000000001379 233.0
REGS2_k127_3636836_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000001198 224.0
REGS2_k127_3636836_3 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000000000000000000007142 170.0
REGS2_k127_3636836_4 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000003138 98.0
REGS2_k127_3653354_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 594.0
REGS2_k127_3653354_1 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 534.0
REGS2_k127_3653354_2 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 502.0
REGS2_k127_3653354_3 Aldehyde dehydrogenase family K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 494.0
REGS2_k127_3653354_4 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 469.0
REGS2_k127_3653354_5 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 362.0
REGS2_k127_3653354_6 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
REGS2_k127_3656570_0 Zinc carboxypeptidase K14054 - - 4.189e-196 624.0
REGS2_k127_3656570_1 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000127 127.0
REGS2_k127_3656570_2 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000003436 109.0
REGS2_k127_3656609_0 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 399.0
REGS2_k127_3656609_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000008933 115.0
REGS2_k127_3656609_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000071 94.0
REGS2_k127_3663925_0 Lamin Tail Domain K07004 - - 1.143e-217 726.0
REGS2_k127_3663925_1 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 514.0
REGS2_k127_3663925_10 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000001003 119.0
REGS2_k127_3663925_11 - - - - 0.000000000000000002917 86.0
REGS2_k127_3663925_12 protein transport - - - 0.000000000000002342 79.0
REGS2_k127_3663925_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 460.0
REGS2_k127_3663925_3 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002141 257.0
REGS2_k127_3663925_4 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000002735 222.0
REGS2_k127_3663925_5 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001157 228.0
REGS2_k127_3663925_6 Lamin Tail Domain K07004 - - 0.0000000000000000000000000000000000000000000000004186 203.0
REGS2_k127_3663925_7 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000003472 178.0
REGS2_k127_3663925_8 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000003694 132.0
REGS2_k127_3663925_9 - - - - 0.00000000000000000000000000159 116.0
REGS2_k127_366545_0 efflux transmembrane transporter activity - - - 1.829e-199 630.0
REGS2_k127_366545_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 565.0
REGS2_k127_366545_2 - - - - 0.00000000000000000000000002438 112.0
REGS2_k127_366545_3 ThiS family K03636 - - 0.0000000000000000002604 92.0
REGS2_k127_366545_4 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000004439 66.0
REGS2_k127_3697584_0 EVE domain - - - 0.0000000000000000000000000000000000000000009925 161.0
REGS2_k127_3697584_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000008756 65.0
REGS2_k127_3697584_2 Alpha/beta hydrolase family - - - 0.0000002126 62.0
REGS2_k127_3697741_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 1.878e-319 1003.0
REGS2_k127_3697741_1 topoisomerase K02469 - 5.99.1.3 3.576e-271 854.0
REGS2_k127_3697741_2 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000002735 182.0
REGS2_k127_3697741_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000002652 132.0
REGS2_k127_3701243_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 2.566e-201 644.0
REGS2_k127_3704196_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 486.0
REGS2_k127_3704196_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 386.0
REGS2_k127_3704196_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000008538 240.0
REGS2_k127_3704196_3 TonB C terminal - - - 0.00000002863 65.0
REGS2_k127_3706411_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000007662 190.0
REGS2_k127_3706411_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000009931 158.0
REGS2_k127_373546_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 426.0
REGS2_k127_373546_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000124 251.0
REGS2_k127_373546_2 cobalamin binding K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000002031 220.0
REGS2_k127_373546_3 nadph quinone reductase - - - 0.00000000000000000000000000001456 127.0
REGS2_k127_373546_4 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.0000000001177 62.0
REGS2_k127_3753454_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 5.875e-206 647.0
REGS2_k127_3753454_1 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.0005175 51.0
REGS2_k127_3760022_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 513.0
REGS2_k127_3760022_1 polyketide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 304.0
REGS2_k127_3760022_2 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004175 240.0
REGS2_k127_3760022_3 BadF BadG BcrA BcrD - - - 0.0000000000002816 79.0
REGS2_k127_3760022_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000005887 65.0
REGS2_k127_3794247_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 343.0
REGS2_k127_3794247_1 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 322.0
REGS2_k127_3794247_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000001139 193.0
REGS2_k127_38353_0 Cytochrome c-type biogenesis protein K02198 - - 2.226e-239 765.0
REGS2_k127_38353_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000007023 183.0
REGS2_k127_38353_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000003187 78.0
REGS2_k127_38353_3 metallopeptidase activity - - - 0.0000000000009511 83.0
REGS2_k127_38353_4 Putative Ig domain - - - 0.00000000003399 78.0
REGS2_k127_3837757_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 402.0
REGS2_k127_3837757_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000006454 168.0
REGS2_k127_3837757_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000236 120.0
REGS2_k127_3850127_0 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 470.0
REGS2_k127_3850127_1 TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 433.0
REGS2_k127_3850127_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000001055 170.0
REGS2_k127_3850127_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000142 68.0
REGS2_k127_3850127_4 Major Facilitator - - - 0.0005446 45.0
REGS2_k127_3939387_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 452.0
REGS2_k127_3939387_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 448.0
REGS2_k127_3939387_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 344.0
REGS2_k127_3939387_3 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 352.0
REGS2_k127_3939387_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001893 265.0
REGS2_k127_3939387_5 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000001087 218.0
REGS2_k127_3939387_6 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000001095 185.0
REGS2_k127_3939387_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000003035 134.0
REGS2_k127_3939387_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000005795 76.0
REGS2_k127_3947620_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 486.0
REGS2_k127_3947620_1 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000004218 133.0
REGS2_k127_3956368_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 498.0
REGS2_k127_3958294_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1024.0
REGS2_k127_3958294_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.059e-266 833.0
REGS2_k127_3958294_10 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000003602 207.0
REGS2_k127_3958294_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000001104 179.0
REGS2_k127_3958294_12 - K00241 - - 0.00000000000000000000000000000000000002728 152.0
REGS2_k127_3958294_13 Protein of unknown function (DUF2905) - - - 0.0000000000000003374 79.0
REGS2_k127_3958294_2 cellulose binding - - - 1.579e-209 676.0
REGS2_k127_3958294_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 531.0
REGS2_k127_3958294_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 501.0
REGS2_k127_3958294_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 443.0
REGS2_k127_3958294_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 358.0
REGS2_k127_3958294_7 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 321.0
REGS2_k127_3958294_8 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
REGS2_k127_3958294_9 domain protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001003 252.0
REGS2_k127_3986426_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 360.0
REGS2_k127_3986426_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 306.0
REGS2_k127_3986426_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000000000000000000001196 183.0
REGS2_k127_3986426_3 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000003882 148.0
REGS2_k127_3992683_0 Peptidase M14, carboxypeptidase A - - - 0.0 1109.0
REGS2_k127_3992683_1 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 520.0
REGS2_k127_3992683_2 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008997 262.0
REGS2_k127_3992683_3 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000287 159.0
REGS2_k127_3992683_4 oxidoreductase activity - - - 0.0000000000000000000000000000000000000004338 168.0
REGS2_k127_4003311_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 516.0
REGS2_k127_4003311_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 444.0
REGS2_k127_4003311_2 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 363.0
REGS2_k127_4003311_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 349.0
REGS2_k127_4003311_4 cyclic nucleotide binding K10914,K21561 - - 0.0000000000000000000000000000000000000000000000000000004072 196.0
REGS2_k127_4003311_5 Hydrogenase maturation protease - - - 0.00000000000000000000000001886 114.0
REGS2_k127_4003311_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000005317 99.0
REGS2_k127_403118_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 586.0
REGS2_k127_403118_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 409.0
REGS2_k127_403118_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000003851 188.0
REGS2_k127_403118_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000005974 103.0
REGS2_k127_403118_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000003222 49.0
REGS2_k127_4105325_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1063.0
REGS2_k127_4105325_1 Electron transfer flavoprotein-ubiquinone K00311 - 1.5.5.1 3.675e-219 694.0
REGS2_k127_4105325_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 465.0
REGS2_k127_4105325_3 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000003228 197.0
REGS2_k127_4105325_4 PFAM Stress-induced bacterial acidophilic repeat motif K06884 - - 0.000000000000003859 80.0
REGS2_k127_4158403_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000007733 172.0
REGS2_k127_4159547_0 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 397.0
REGS2_k127_4159547_1 methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 326.0
REGS2_k127_4159547_2 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000000101 175.0
REGS2_k127_4159547_3 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000005738 104.0
REGS2_k127_4159547_4 Redoxin K03564 - 1.11.1.15 0.000000000000007626 78.0
REGS2_k127_4159547_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000008513 59.0
REGS2_k127_4183154_0 diguanylate cyclase - - - 0.00000000000000000000000000001149 132.0
REGS2_k127_4183154_1 Protein of unknown function (DUF1343) - - - 0.0000000001164 64.0
REGS2_k127_4232975_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000001191 233.0
REGS2_k127_4232975_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000003252 211.0
REGS2_k127_4232975_2 Glycosyl transferase 4-like - - - 0.00000000000751 70.0
REGS2_k127_4311453_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.099e-235 753.0
REGS2_k127_4311453_1 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000344 292.0
REGS2_k127_4311453_2 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000001356 143.0
REGS2_k127_4322821_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 5.587e-314 975.0
REGS2_k127_4322821_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 587.0
REGS2_k127_4322821_10 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001768 291.0
REGS2_k127_4322821_11 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004049 291.0
REGS2_k127_4322821_12 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002945 277.0
REGS2_k127_4322821_13 PFAM glycosyl transferase group 1 K12995,K13668 - 2.4.1.346,2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000002406 267.0
REGS2_k127_4322821_14 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000002936 233.0
REGS2_k127_4322821_15 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
REGS2_k127_4322821_16 - - - - 0.000000000000000000000000000000000000000000000000000000000002863 228.0
REGS2_k127_4322821_17 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
REGS2_k127_4322821_18 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000001934 215.0
REGS2_k127_4322821_19 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.00000000000000000000000000000000000000000000000000005254 204.0
REGS2_k127_4322821_2 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 458.0
REGS2_k127_4322821_20 - - - - 0.0000000000000000000000000000000000000000000000000001632 193.0
REGS2_k127_4322821_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000001995 188.0
REGS2_k127_4322821_22 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000001191 183.0
REGS2_k127_4322821_23 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000006843 169.0
REGS2_k127_4322821_24 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000001004 162.0
REGS2_k127_4322821_25 Cephalosporin hydroxylase - - - 0.0000000000000000000000000000000000008117 153.0
REGS2_k127_4322821_26 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000001083 151.0
REGS2_k127_4322821_27 Ribosomal protein L11 methyltransferase (PrmA) K11434 - 2.1.1.319 0.00000000000000000000000000000000000743 151.0
REGS2_k127_4322821_28 ABC transporter K01990 - - 0.00000000000000000000000000000000002471 145.0
REGS2_k127_4322821_29 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000002991 147.0
REGS2_k127_4322821_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 448.0
REGS2_k127_4322821_30 Glycosyl transferases group 1 - - - 0.000000000000000000000000000025 135.0
REGS2_k127_4322821_31 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000248 119.0
REGS2_k127_4322821_32 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000002823 130.0
REGS2_k127_4322821_33 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000003251 124.0
REGS2_k127_4322821_34 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000311 119.0
REGS2_k127_4322821_35 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000157 114.0
REGS2_k127_4322821_36 O-Antigen ligase K02847 - - 0.0000000000000000000005052 110.0
REGS2_k127_4322821_37 Methyltransferase domain - - - 0.000000000000000000005634 102.0
REGS2_k127_4322821_38 polysaccharide biosynthetic process - - - 0.00000000000000000001239 106.0
REGS2_k127_4322821_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 437.0
REGS2_k127_4322821_40 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000006145 90.0
REGS2_k127_4322821_41 PFAM ABC-2 type transporter K01992 - - 0.000000000000002006 86.0
REGS2_k127_4322821_43 Methyltransferase domain - - - 0.0000000000002031 82.0
REGS2_k127_4322821_44 COG0500 SAM-dependent methyltransferases - - - 0.000000000003772 79.0
REGS2_k127_4322821_45 HPr kinase - - - 0.0000000002211 72.0
REGS2_k127_4322821_46 - - - - 0.0000003175 63.0
REGS2_k127_4322821_47 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0005094 51.0
REGS2_k127_4322821_5 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 404.0
REGS2_k127_4322821_6 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 377.0
REGS2_k127_4322821_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 366.0
REGS2_k127_4322821_8 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 326.0
REGS2_k127_4322821_9 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 311.0
REGS2_k127_4327465_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.158e-263 825.0
REGS2_k127_4327465_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 9.215e-245 778.0
REGS2_k127_4327465_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 318.0
REGS2_k127_4327465_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 302.0
REGS2_k127_4327465_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003052 250.0
REGS2_k127_4327465_5 pfam nudix K01515 - 3.6.1.13 0.000000000000000000000000000000000000003917 151.0
REGS2_k127_4327465_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001582 124.0
REGS2_k127_433258_0 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 618.0
REGS2_k127_433258_1 - - - - 0.0004386 52.0
REGS2_k127_4336883_1 - - - - 0.00000000000000000008654 100.0
REGS2_k127_4352174_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 404.0
REGS2_k127_4352174_1 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 314.0
REGS2_k127_4352174_2 FAD binding domain K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008116 293.0
REGS2_k127_4352174_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002681 239.0
REGS2_k127_4352174_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000007873 213.0
REGS2_k127_4352174_5 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000001352 181.0
REGS2_k127_4352174_6 YceI-like domain - - - 0.0000000000000000000000000000000000000002763 157.0
REGS2_k127_4353711_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 609.0
REGS2_k127_4353711_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 504.0
REGS2_k127_4353711_2 Peptidase S9 prolyl oligopeptidase active site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004908 281.0
REGS2_k127_4353711_3 PFAM Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000004519 199.0
REGS2_k127_4353711_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000006601 63.0
REGS2_k127_4354846_0 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 304.0
REGS2_k127_4354846_1 Putative regulatory protein - - - 0.00000000000000005504 82.0
REGS2_k127_4354846_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000009762 90.0
REGS2_k127_4354846_3 SNARE associated Golgi protein - - - 0.000000001621 64.0
REGS2_k127_4355447_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 466.0
REGS2_k127_4355447_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 307.0
REGS2_k127_4355447_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000002869 230.0
REGS2_k127_4355447_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
REGS2_k127_4355447_4 B3/4 domain - - - 0.0000000000000000000000000000002013 130.0
REGS2_k127_4355447_6 - - - - 0.00001288 48.0
REGS2_k127_4357820_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002001 282.0
REGS2_k127_4362738_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 4.445e-257 820.0
REGS2_k127_4362738_1 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 407.0
REGS2_k127_4362738_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 403.0
REGS2_k127_4362738_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 358.0
REGS2_k127_4362738_4 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008361 243.0
REGS2_k127_4362738_5 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000003153 186.0
REGS2_k127_4369116_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 398.0
REGS2_k127_4369116_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 376.0
REGS2_k127_4369116_2 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002113 284.0
REGS2_k127_4369116_3 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002 267.0
REGS2_k127_4369116_4 Tetratricopeptide repeat - - - 0.00000000000000000000002237 114.0
REGS2_k127_4372268_0 Methionine synthase K00548 - 2.1.1.13 0.0 1481.0
REGS2_k127_4372268_1 serine-type peptidase activity K01278 - 3.4.14.5 7.985e-226 722.0
REGS2_k127_4372268_10 TIGRFAM nicotinamide mononucleotide transporter PnuC K03811 - - 0.0000000000000000000000000000000000000000000000000009453 192.0
REGS2_k127_4372268_11 COG1555 DNA uptake protein and related DNA-binding proteins - - - 0.00000000000000000000000000000004215 145.0
REGS2_k127_4372268_12 PFAM PEGA domain - - - 0.00000000001179 79.0
REGS2_k127_4372268_13 - - - - 0.00002414 53.0
REGS2_k127_4372268_2 Oligopeptidase F K08602 - - 1.753e-205 664.0
REGS2_k127_4372268_3 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 324.0
REGS2_k127_4372268_4 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 289.0
REGS2_k127_4372268_5 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 289.0
REGS2_k127_4372268_6 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001733 302.0
REGS2_k127_4372268_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000002905 243.0
REGS2_k127_4372268_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000109 207.0
REGS2_k127_4372268_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000008768 203.0
REGS2_k127_4413871_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 547.0
REGS2_k127_4413871_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000008536 115.0
REGS2_k127_4432103_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 419.0
REGS2_k127_4432103_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 346.0
REGS2_k127_4432103_10 PFAM response regulator receiver - - - 0.00000000000000006262 91.0
REGS2_k127_4432103_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000127 64.0
REGS2_k127_4432103_12 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000008398 59.0
REGS2_k127_4432103_2 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 346.0
REGS2_k127_4432103_3 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 311.0
REGS2_k127_4432103_4 4 iron, 4 sulfur cluster binding K17996 - 1.12.98.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002318 271.0
REGS2_k127_4432103_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001326 241.0
REGS2_k127_4432103_6 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000002447 222.0
REGS2_k127_4432103_7 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000001328 181.0
REGS2_k127_4432103_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000002842 113.0
REGS2_k127_4432103_9 phosphorelay signal transduction system - - - 0.00000000000000000008286 94.0
REGS2_k127_4443903_0 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 444.0
REGS2_k127_4443903_1 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 329.0
REGS2_k127_4443903_2 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 293.0
REGS2_k127_4465734_0 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000001989 102.0
REGS2_k127_4465734_1 - - - - 0.000000000000000004399 89.0
REGS2_k127_4465734_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000003146 80.0
REGS2_k127_4465782_0 PFAM Catalase domain protein K03781 - 1.11.1.6 4.503e-319 982.0
REGS2_k127_4465782_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.476e-250 799.0
REGS2_k127_4465782_10 Domain of unknown function (DUF4870) - - - 0.000002835 58.0
REGS2_k127_4465782_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 496.0
REGS2_k127_4465782_3 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 463.0
REGS2_k127_4465782_4 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001176 290.0
REGS2_k127_4465782_5 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000000000000000000001481 198.0
REGS2_k127_4465782_6 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000005097 143.0
REGS2_k127_4465782_7 PrcB C-terminal - - - 0.0000000000001915 79.0
REGS2_k127_4465782_8 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000003037 68.0
REGS2_k127_4474255_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 379.0
REGS2_k127_4474255_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004126 244.0
REGS2_k127_4474255_2 Protein of unknown function (DUF1706) - - - 0.0002028 49.0
REGS2_k127_4478156_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 552.0
REGS2_k127_4478156_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 454.0
REGS2_k127_4478156_2 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 425.0
REGS2_k127_4478156_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 361.0
REGS2_k127_4478156_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 346.0
REGS2_k127_4478156_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 304.0
REGS2_k127_4478156_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000005983 195.0
REGS2_k127_4478156_7 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000001008 173.0
REGS2_k127_4478156_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000005227 167.0
REGS2_k127_4478156_9 - - - - 0.0000000000000000000009371 112.0
REGS2_k127_4494794_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 413.0
REGS2_k127_4494794_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004774 234.0
REGS2_k127_4494794_2 - K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000001776 238.0
REGS2_k127_4494794_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000002522 203.0
REGS2_k127_4494794_4 peptidase M36 K01417 - - 0.00000000000000000000000000000000000000000000000000000644 219.0
REGS2_k127_4494794_5 Protein of unknown function (DUF3616) K07004 - - 0.0000000000009744 83.0
REGS2_k127_4494794_6 Pregnancy-associated plasma protein-A - - - 0.0000009133 63.0
REGS2_k127_4494794_7 Membrane - - - 0.000003682 55.0
REGS2_k127_4507761_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.043e-285 901.0
REGS2_k127_4507761_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.07e-271 859.0
REGS2_k127_4507761_10 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000002904 104.0
REGS2_k127_4507761_11 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000005781 74.0
REGS2_k127_4507761_12 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000007055 71.0
REGS2_k127_4507761_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000001009 71.0
REGS2_k127_4507761_14 Belongs to the ParB family K03497 - - 0.00000000001482 66.0
REGS2_k127_4507761_2 ATP-dependent DNA helicase K03657 - 3.6.4.12 1.048e-200 649.0
REGS2_k127_4507761_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.195e-197 641.0
REGS2_k127_4507761_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 500.0
REGS2_k127_4507761_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 352.0
REGS2_k127_4507761_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 314.0
REGS2_k127_4507761_7 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
REGS2_k127_4507761_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001939 298.0
REGS2_k127_4507761_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000204 104.0
REGS2_k127_452318_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 375.0
REGS2_k127_452318_1 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 368.0
REGS2_k127_452318_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
REGS2_k127_452318_3 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000306 153.0
REGS2_k127_452318_4 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000005319 121.0
REGS2_k127_452318_5 domain protein - - - 0.0000002848 59.0
REGS2_k127_4545711_0 DNA polymerase X K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 546.0
REGS2_k127_4545711_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 435.0
REGS2_k127_4545711_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 306.0
REGS2_k127_4545711_3 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 297.0
REGS2_k127_4545711_4 allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 263.0
REGS2_k127_4545711_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000009653 207.0
REGS2_k127_4545711_6 Pfam:AHS1 - - - 0.0000000000000000000000000000000000000000000000000002199 195.0
REGS2_k127_4545711_7 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0008381 44.0
REGS2_k127_4547390_0 Urocanase C-terminal domain K01712 - 4.2.1.49 6.005e-259 808.0
REGS2_k127_4547390_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 521.0
REGS2_k127_4547390_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 451.0
REGS2_k127_4547390_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000001716 199.0
REGS2_k127_4547390_4 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000002281 157.0
REGS2_k127_4547390_5 AAA ATPase domain - - - 0.0000000002552 73.0
REGS2_k127_4561656_0 ASPIC and UnbV - - - 6.644e-258 812.0
REGS2_k127_4561656_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 547.0
REGS2_k127_4561656_10 Methyltransferase domain K00598 - 2.1.1.144 0.000000000757 68.0
REGS2_k127_4561656_11 HflC and HflK could regulate a protease K04087 - - 0.00000003873 55.0
REGS2_k127_4561656_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 492.0
REGS2_k127_4561656_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001622 262.0
REGS2_k127_4561656_4 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002737 252.0
REGS2_k127_4561656_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000001539 242.0
REGS2_k127_4561656_6 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000001342 210.0
REGS2_k127_4561656_7 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000000006914 190.0
REGS2_k127_4561656_8 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000114 126.0
REGS2_k127_4561656_9 Domain of unknown function (DUF378) - - - 0.000000000000000004399 89.0
REGS2_k127_4567552_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 8.366e-275 870.0
REGS2_k127_4567552_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 617.0
REGS2_k127_4567552_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000009084 196.0
REGS2_k127_4567552_3 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00003999 49.0
REGS2_k127_4586467_0 metallocarboxypeptidase activity K14054 - - 0.0 1169.0
REGS2_k127_4586467_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 1.229e-257 803.0
REGS2_k127_4586467_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001223 259.0
REGS2_k127_4586467_3 WYL domain K13572 - - 0.00000000000000000000000000000000000000000000000006574 190.0
REGS2_k127_4586467_4 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000005114 182.0
REGS2_k127_4586467_5 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000001714 117.0
REGS2_k127_4586467_6 cheY-homologous receiver domain - - - 0.00000000000000000000001998 108.0
REGS2_k127_4586467_7 RNA recognition motif - - - 0.0000000000000000003095 95.0
REGS2_k127_4586467_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000003585 75.0
REGS2_k127_4586467_9 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0001372 54.0
REGS2_k127_4608838_0 Pfam:KaiC K08482 - - 1.627e-194 619.0
REGS2_k127_4608838_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002054 272.0
REGS2_k127_4608838_2 KaiB K08481 - - 0.00000000000000000000000000000000001554 149.0
REGS2_k127_4608838_3 KaiB K08481 - - 0.00000000000000008255 80.0
REGS2_k127_4614378_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 6.661e-262 824.0
REGS2_k127_4614378_1 Carbon starvation protein K06200 - - 2.79e-220 700.0
REGS2_k127_4614378_2 Belongs to the proline racemase family K01777 - 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 346.0
REGS2_k127_4614378_3 von Willebrand factor, type A - - - 0.00000000000000000000000000005552 127.0
REGS2_k127_4614378_4 PFAM ThiS family K03636 - - 0.00000415 51.0
REGS2_k127_4617693_0 PFAM type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 473.0
REGS2_k127_4617693_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
REGS2_k127_4617693_2 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000006024 220.0
REGS2_k127_4617693_3 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000002123 211.0
REGS2_k127_4617693_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000004898 103.0
REGS2_k127_4617693_5 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000002314 91.0
REGS2_k127_4634763_0 Domain of unknown function (DUF5009) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 310.0
REGS2_k127_4634763_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001241 243.0
REGS2_k127_4649402_0 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000000000000000000000000009341 164.0
REGS2_k127_4649402_1 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.000000000000000000000000000000001869 131.0
REGS2_k127_4649402_2 Domain of unknown function (DUF4390) - - - 0.00000003593 61.0
REGS2_k127_4655162_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
REGS2_k127_4655162_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 491.0
REGS2_k127_4655162_10 PFAM Glycosyl transferase family 2 - - - 0.000001117 52.0
REGS2_k127_4655162_11 CarboxypepD_reg-like domain - - - 0.00004963 57.0
REGS2_k127_4655162_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 312.0
REGS2_k127_4655162_3 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000001131 215.0
REGS2_k127_4655162_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000001186 205.0
REGS2_k127_4655162_5 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000846 118.0
REGS2_k127_4655162_6 Phosphopantetheine attachment site K02078 - - 0.0000000000000004418 81.0
REGS2_k127_4655162_8 exporters of the RND superfamily - - - 0.00000000000001343 88.0
REGS2_k127_4655162_9 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000004784 63.0
REGS2_k127_4720861_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1193.0
REGS2_k127_4720861_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 459.0
REGS2_k127_4720861_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000005583 205.0
REGS2_k127_4720861_11 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000223 163.0
REGS2_k127_4720861_12 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000001038 156.0
REGS2_k127_4720861_13 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000001374 147.0
REGS2_k127_4720861_14 Thymidylate kinase K00943 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0022414,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0050145,GO:0055086,GO:0061458,GO:0070013,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000002551 121.0
REGS2_k127_4720861_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000006997 120.0
REGS2_k127_4720861_16 PFAM NLP P60 protein - - - 0.00000000000000000000002864 113.0
REGS2_k127_4720861_17 Radical SAM superfamily - - - 0.0000000000000000000001673 112.0
REGS2_k127_4720861_18 - - - - 0.000000000000000001974 96.0
REGS2_k127_4720861_19 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000009643 71.0
REGS2_k127_4720861_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 374.0
REGS2_k127_4720861_20 Acetyltransferase (GNAT) domain - - - 0.00000001492 64.0
REGS2_k127_4720861_21 TIGRFAM amino acid adenylation domain - - - 0.0000006592 62.0
REGS2_k127_4720861_3 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 348.0
REGS2_k127_4720861_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 306.0
REGS2_k127_4720861_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001341 287.0
REGS2_k127_4720861_6 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002436 264.0
REGS2_k127_4720861_7 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000004511 252.0
REGS2_k127_4720861_8 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000002003 237.0
REGS2_k127_4720861_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002495 229.0
REGS2_k127_4741370_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 569.0
REGS2_k127_4741370_1 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 377.0
REGS2_k127_4741370_2 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000004233 232.0
REGS2_k127_4741370_3 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000005022 168.0
REGS2_k127_4741370_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000001134 155.0
REGS2_k127_4741370_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001089 101.0
REGS2_k127_4741370_6 endonuclease containing a URI domain K07461 - - 0.000000000000000000003175 98.0
REGS2_k127_4760909_0 Sodium:solute symporter family - - - 6.81e-273 850.0
REGS2_k127_4760909_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 520.0
REGS2_k127_4760909_2 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 360.0
REGS2_k127_4760909_3 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000003419 74.0
REGS2_k127_4829008_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1138.0
REGS2_k127_4829008_1 Response regulator, receiver K01007 - 2.7.9.2 0.0 1022.0
REGS2_k127_4829008_10 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 287.0
REGS2_k127_4829008_11 oxidoreductase activity - - - 0.000000000000000000000000000000000784 150.0
REGS2_k127_4829008_12 Domain of unknown function (DUF4824) - - - 0.0000000000000000000000002478 122.0
REGS2_k127_4829008_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 1.014e-244 762.0
REGS2_k127_4829008_3 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 1.041e-218 684.0
REGS2_k127_4829008_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 574.0
REGS2_k127_4829008_5 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 543.0
REGS2_k127_4829008_6 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 346.0
REGS2_k127_4829008_7 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 340.0
REGS2_k127_4829008_8 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 304.0
REGS2_k127_4829008_9 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 295.0
REGS2_k127_4862063_0 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 413.0
REGS2_k127_4862063_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 331.0
REGS2_k127_4862063_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000003339 186.0
REGS2_k127_4862063_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000002858 99.0
REGS2_k127_4862063_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000227 90.0
REGS2_k127_4874632_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 294.0
REGS2_k127_4874632_1 Glycosyl hydrolase-like 10 - - - 0.000000000000000002378 95.0
REGS2_k127_4916951_0 Peptidase family M3 K01284 - 3.4.15.5 1.44e-316 983.0
REGS2_k127_4916951_1 lysine biosynthetic process via aminoadipic acid - - - 8.935e-202 659.0
REGS2_k127_4916951_10 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001179 258.0
REGS2_k127_4916951_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000008386 241.0
REGS2_k127_4916951_12 - - - - 0.000000000000000000000000000000891 137.0
REGS2_k127_4916951_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 398.0
REGS2_k127_4916951_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 380.0
REGS2_k127_4916951_4 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 347.0
REGS2_k127_4916951_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 343.0
REGS2_k127_4916951_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 337.0
REGS2_k127_4916951_7 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 339.0
REGS2_k127_4916951_8 oxidoreductase activity K00665 - 2.3.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 314.0
REGS2_k127_4916951_9 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
REGS2_k127_4925088_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.663e-245 765.0
REGS2_k127_4937352_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 584.0
REGS2_k127_4937352_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 414.0
REGS2_k127_4937352_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 421.0
REGS2_k127_4937352_3 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 327.0
REGS2_k127_4937352_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000006485 190.0
REGS2_k127_493800_0 hydrolase, family 3 K05349 - 3.2.1.21 6.985e-268 842.0
REGS2_k127_493800_1 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 423.0
REGS2_k127_493800_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000004483 87.0
REGS2_k127_4953907_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 3.761e-223 707.0
REGS2_k127_4977364_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.843e-220 697.0
REGS2_k127_4977364_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 549.0
REGS2_k127_4977364_2 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003215 285.0
REGS2_k127_4977364_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000002197 227.0
REGS2_k127_4977364_4 Yip1 domain - - - 0.000000000003276 76.0
REGS2_k127_4977364_5 long-chain fatty acid transporting porin activity K06076 - - 0.000000005379 68.0
REGS2_k127_4987212_0 Sortilin, neurotensin receptor 3, - - - 0.0 1242.0
REGS2_k127_4987212_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 294.0
REGS2_k127_4987212_2 Protein tyrosine kinase - - - 0.000000000000000000000000000008112 123.0
REGS2_k127_4987212_3 metal-dependent phosphoesterases (PHP family) - - - 0.00000000000000009031 89.0
REGS2_k127_4987212_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.00004577 51.0
REGS2_k127_5050986_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 550.0
REGS2_k127_5050986_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 332.0
REGS2_k127_5050986_2 hydroperoxide reductase activity - - - 0.000000000000000000004102 96.0
REGS2_k127_5050986_3 - - - - 0.0000000000000000004999 92.0
REGS2_k127_5050986_4 hydroperoxide reductase activity - - - 0.000000000000001376 81.0
REGS2_k127_5050986_5 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000005917 63.0
REGS2_k127_5050986_6 - - - - 0.00000005609 64.0
REGS2_k127_5099097_0 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 376.0
REGS2_k127_5111618_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 326.0
REGS2_k127_5111618_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 249.0
REGS2_k127_5111618_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000001021 171.0
REGS2_k127_5154579_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 599.0
REGS2_k127_5154579_1 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002907 274.0
REGS2_k127_5154579_2 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002127 272.0
REGS2_k127_5154579_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000002583 188.0
REGS2_k127_5154579_4 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000003536 168.0
REGS2_k127_5154579_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000001076 157.0
REGS2_k127_5154579_6 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000000000009889 90.0
REGS2_k127_5154579_7 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000001265 73.0
REGS2_k127_5154579_8 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000001957 74.0
REGS2_k127_5154579_9 PLD-like domain - - - 0.00009702 56.0
REGS2_k127_5176792_0 Dienelactone hydrolase family - - - 5.355e-251 792.0
REGS2_k127_5176792_1 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 2.48e-210 660.0
REGS2_k127_5176792_10 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000003051 88.0
REGS2_k127_5176792_11 PFAM Methionine synthase, B12-binding module, cap domain protein K00548 - 2.1.1.13 0.000000000000001731 79.0
REGS2_k127_5176792_2 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 2.25e-202 654.0
REGS2_k127_5176792_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 583.0
REGS2_k127_5176792_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 561.0
REGS2_k127_5176792_5 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 584.0
REGS2_k127_5176792_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 458.0
REGS2_k127_5176792_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 327.0
REGS2_k127_5176792_8 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 305.0
REGS2_k127_5176792_9 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
REGS2_k127_5199754_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 550.0
REGS2_k127_5199754_1 Acyl-CoA dehydrogenase, C-terminal domain K04117 - - 0.000000000000000000000000000000000000000000000000000000225 196.0
REGS2_k127_5213305_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1173.0
REGS2_k127_5213305_1 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 335.0
REGS2_k127_5213305_10 - - - - 0.00000000002419 71.0
REGS2_k127_5213305_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 324.0
REGS2_k127_5213305_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 299.0
REGS2_k127_5213305_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003141 280.0
REGS2_k127_5213305_5 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005312 299.0
REGS2_k127_5213305_6 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000164 200.0
REGS2_k127_5213305_7 s1 p1 nuclease - - - 0.0000000000000000000000000000000000002047 154.0
REGS2_k127_5213305_8 MgtC family K07507 - - 0.0000000000000000000000000000000001585 137.0
REGS2_k127_5213305_9 Matrixin - - - 0.0000000000006352 81.0
REGS2_k127_5215392_0 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 4.625e-275 861.0
REGS2_k127_5215392_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 443.0
REGS2_k127_5215392_2 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 399.0
REGS2_k127_5215392_3 DinB superfamily - - - 0.00000000000000000000000003252 113.0
REGS2_k127_5223265_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.186e-208 655.0
REGS2_k127_5223265_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 402.0
REGS2_k127_5223265_10 PFAM CHAD domain containing protein - - - 0.00000327 59.0
REGS2_k127_5223265_11 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0002298 44.0
REGS2_k127_5223265_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 357.0
REGS2_k127_5223265_3 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 288.0
REGS2_k127_5223265_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
REGS2_k127_5223265_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000001557 222.0
REGS2_k127_5223265_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000008014 151.0
REGS2_k127_5223265_7 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000773 119.0
REGS2_k127_5223265_8 SET domain K07117 - - 0.00000000000008417 78.0
REGS2_k127_5223265_9 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000001483 63.0
REGS2_k127_5226833_0 Domain of unknown function (DUF5117) - - - 0.0 1007.0
REGS2_k127_5226833_1 efflux transmembrane transporter activity - - - 1.082e-281 901.0
REGS2_k127_5226833_2 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 517.0
REGS2_k127_5226833_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000005056 115.0
REGS2_k127_5236597_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
REGS2_k127_5236597_1 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 405.0
REGS2_k127_5236597_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 384.0
REGS2_k127_5236597_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 301.0
REGS2_k127_5240570_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000258 193.0
REGS2_k127_5240570_1 oxidoreductase activity - - - 0.0000000001593 74.0
REGS2_k127_5249311_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000008486 203.0
REGS2_k127_5249311_1 EthD domain - - - 0.000000000000000000000000000000000000000000000009051 171.0
REGS2_k127_5249311_2 LysE type translocator - - - 0.000000000000000000000000000000000001418 142.0
REGS2_k127_5249311_3 Thioesterase K07107 - - 0.00000000000007886 72.0
REGS2_k127_5257638_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
REGS2_k127_5257638_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000001691 184.0
REGS2_k127_5257638_2 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000001464 160.0
REGS2_k127_5257638_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000148 145.0
REGS2_k127_5257638_4 Peptidase_C39 like family - - - 0.00001576 58.0
REGS2_k127_5260122_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 576.0
REGS2_k127_5260122_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 456.0
REGS2_k127_5265459_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 1.938e-230 724.0
REGS2_k127_5265459_1 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 495.0
REGS2_k127_5265459_2 von Willebrand factor, type A K12511 - - 0.00000000000000008958 90.0
REGS2_k127_5275773_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 456.0
REGS2_k127_5275773_1 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 416.0
REGS2_k127_5275773_2 response regulator K02481,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 364.0
REGS2_k127_5275773_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 294.0
REGS2_k127_5275773_4 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000148 164.0
REGS2_k127_5300954_0 helicase activity - - - 1.004e-259 822.0
REGS2_k127_5300954_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000005673 234.0
REGS2_k127_5308690_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 348.0
REGS2_k127_5308690_1 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 329.0
REGS2_k127_5308690_2 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 323.0
REGS2_k127_5308690_3 ATPase activity K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 311.0
REGS2_k127_5308690_4 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000001632 196.0
REGS2_k127_5308690_5 outer membrane efflux protein - - - 0.00000000000000000000000000002446 134.0
REGS2_k127_5308690_6 transcriptional regulator - - - 0.000000000000000000000000001262 119.0
REGS2_k127_5320995_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 490.0
REGS2_k127_5320995_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002063 289.0
REGS2_k127_5320995_2 Pfam:N_methyl_2 - - - 0.0000000000000001584 87.0
REGS2_k127_5320995_3 Type II secretory pathway component PulF K02653 - - 0.00001857 47.0
REGS2_k127_5408987_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.533e-248 778.0
REGS2_k127_5408987_1 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 585.0
REGS2_k127_5408987_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 340.0
REGS2_k127_5408987_3 Glycosyl transferase 4-like domain K08256,K12995 - 2.4.1.345,2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003686 290.0
REGS2_k127_5408987_4 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 254.0
REGS2_k127_5408987_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000004548 155.0
REGS2_k127_5408987_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000003469 84.0
REGS2_k127_5408987_7 chlorophyll binding - - - 0.0002826 53.0
REGS2_k127_5446228_0 Sigma-54 interaction domain K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 403.0
REGS2_k127_5446228_1 GAF domain - - - 0.0000000000000000000000000000000001523 151.0
REGS2_k127_5446228_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000009318 134.0
REGS2_k127_5446228_3 - - - - 0.000002832 49.0
REGS2_k127_5450764_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000001263 64.0
REGS2_k127_5454474_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 371.0
REGS2_k127_5454474_1 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000886 219.0
REGS2_k127_5460047_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.512e-201 635.0
REGS2_k127_5460047_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
REGS2_k127_5460047_2 Putative peptidoglycan binding domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000002003 246.0
REGS2_k127_5460047_3 Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000001616 207.0
REGS2_k127_5460047_4 - - - - 0.0000000000000000003228 94.0
REGS2_k127_5460047_5 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000001207 89.0
REGS2_k127_5460047_6 Bacterial type II and III secretion system protein K12282 - - 0.0000000001237 74.0
REGS2_k127_5460047_7 O-methyltransferase - - - 0.0000000002627 70.0
REGS2_k127_5463858_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 593.0
REGS2_k127_5463858_1 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 327.0
REGS2_k127_5463858_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000001176 177.0
REGS2_k127_5474569_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.095e-298 928.0
REGS2_k127_5474569_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 4.76e-251 782.0
REGS2_k127_5474569_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000006773 248.0
REGS2_k127_5474569_11 COG2998 ABC-type tungstate transport system, permease component K05772 - - 0.00000000000000000000000000000000000000000000000148 184.0
REGS2_k127_5474569_12 AI-2E family transporter - - - 0.000000000000000000000000000000000000507 153.0
REGS2_k127_5474569_13 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000002413 137.0
REGS2_k127_5474569_14 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000000000003807 107.0
REGS2_k127_5474569_15 Endoribonuclease L-PSP - - - 0.0000000000000000008066 91.0
REGS2_k127_5474569_16 Protein of unknown function (DUF2934) - - - 0.0001854 49.0
REGS2_k127_5474569_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.707e-223 699.0
REGS2_k127_5474569_3 Cytochrome c - - - 2.054e-199 627.0
REGS2_k127_5474569_4 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 540.0
REGS2_k127_5474569_5 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 505.0
REGS2_k127_5474569_6 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 392.0
REGS2_k127_5474569_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 372.0
REGS2_k127_5474569_8 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001922 270.0
REGS2_k127_5474569_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008573 257.0
REGS2_k127_5501871_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000001402 162.0
REGS2_k127_5501871_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.0000000000000000000000003136 106.0
REGS2_k127_5501871_2 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.000000000001128 78.0
REGS2_k127_5535858_0 Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 552.0
REGS2_k127_5535858_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000003452 63.0
REGS2_k127_5560014_0 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 597.0
REGS2_k127_5560014_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 393.0
REGS2_k127_5560014_2 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 374.0
REGS2_k127_5560014_3 protein secretion K09800 - - 0.0000000000000000000000000726 128.0
REGS2_k127_5568964_0 Fibronectin type III-like domain K05349 - 3.2.1.21 5.882e-301 948.0
REGS2_k127_5568964_1 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000006305 241.0
REGS2_k127_5568964_2 Tricorn protease homolog K08676 - - 0.000000005667 58.0
REGS2_k127_5568964_3 - - - - 0.00000002409 61.0
REGS2_k127_5573066_0 cellulose binding - - - 2.904e-264 847.0
REGS2_k127_5573066_1 TonB dependent receptor - - - 5.876e-257 822.0
REGS2_k127_5573066_2 hydrolase, family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 366.0
REGS2_k127_5588602_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 321.0
REGS2_k127_5588602_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000007576 181.0
REGS2_k127_5588602_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000002413 137.0
REGS2_k127_5588602_3 Sporulation and spore germination - - - 0.0000000000000000000004559 107.0
REGS2_k127_5605630_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 597.0
REGS2_k127_5605630_1 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 569.0
REGS2_k127_5613958_0 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 391.0
REGS2_k127_5613958_1 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000002459 164.0
REGS2_k127_5613958_2 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000005113 154.0
REGS2_k127_5613958_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000001122 130.0
REGS2_k127_5613958_4 oxidoreductase activity - - - 0.000000000000221 83.0
REGS2_k127_5613958_5 SnoaL-like domain - - - 0.00000002025 62.0
REGS2_k127_5618269_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000003794 116.0
REGS2_k127_5626973_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 460.0
REGS2_k127_5626973_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 337.0
REGS2_k127_5626973_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 334.0
REGS2_k127_5626973_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000005786 137.0
REGS2_k127_5626973_4 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000001257 90.0
REGS2_k127_5626973_5 - K01992 - - 0.000000000005935 76.0
REGS2_k127_5626973_6 23S rRNA-intervening sequence protein - - - 0.0000002308 58.0
REGS2_k127_5677191_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 9.75e-199 627.0
REGS2_k127_5677191_1 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000000000000000000000000005262 225.0
REGS2_k127_5677191_2 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000005045 166.0
REGS2_k127_5677191_3 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000002211 154.0
REGS2_k127_5677191_4 Tetratricopeptide repeat - - - 0.00000000008584 74.0
REGS2_k127_5776265_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 372.0
REGS2_k127_5793505_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 584.0
REGS2_k127_5793505_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000002691 175.0
REGS2_k127_5793505_2 Tetratricopeptide repeat - - - 0.000000000000000000006368 108.0
REGS2_k127_5793505_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000003808 96.0
REGS2_k127_5817395_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.922e-202 642.0
REGS2_k127_5817395_1 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 361.0
REGS2_k127_5817395_2 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 295.0
REGS2_k127_5817395_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 289.0
REGS2_k127_5817395_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000055 111.0
REGS2_k127_5825009_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 371.0
REGS2_k127_5825009_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000002666 243.0
REGS2_k127_586096_0 Major facilitator Superfamily K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 544.0
REGS2_k127_586096_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 454.0
REGS2_k127_586096_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 361.0
REGS2_k127_5874624_0 cellulose binding - - - 0.0 1246.0
REGS2_k127_5874624_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 6.37e-322 1010.0
REGS2_k127_5874624_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000007509 216.0
REGS2_k127_5874624_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000006435 226.0
REGS2_k127_5874624_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000002629 198.0
REGS2_k127_5874624_13 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000004083 127.0
REGS2_k127_5874624_14 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000001245 118.0
REGS2_k127_5874624_15 Pyrrolo-quinoline quinone - - - 0.00000000000000000001893 104.0
REGS2_k127_5874624_16 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000531 85.0
REGS2_k127_5874624_17 Protein of unknown function (DUF465) - - - 0.0000000006385 63.0
REGS2_k127_5874624_18 protein trimerization - - - 0.000000006276 66.0
REGS2_k127_5874624_2 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.689e-269 854.0
REGS2_k127_5874624_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 4.679e-203 644.0
REGS2_k127_5874624_4 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 385.0
REGS2_k127_5874624_5 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 359.0
REGS2_k127_5874624_6 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 329.0
REGS2_k127_5874624_7 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 314.0
REGS2_k127_5874624_8 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000003029 264.0
REGS2_k127_5874624_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000003482 215.0
REGS2_k127_5905005_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1075.0
REGS2_k127_5905005_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000005539 146.0
REGS2_k127_5910663_0 cellulose binding - - - 0.0 1030.0
REGS2_k127_5910663_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000005251 100.0
REGS2_k127_5910663_2 Zinc carboxypeptidase - - - 0.00000002273 56.0
REGS2_k127_5993484_0 PFAM response regulator receiver K07713 - - 3.41e-198 626.0
REGS2_k127_5993484_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 518.0
REGS2_k127_5993484_2 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 479.0
REGS2_k127_5993484_3 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002244 290.0
REGS2_k127_5993484_4 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000786 168.0
REGS2_k127_5993484_5 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000016 152.0
REGS2_k127_5993484_6 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000001735 134.0
REGS2_k127_59974_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 560.0
REGS2_k127_59974_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 538.0
REGS2_k127_59974_2 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 461.0
REGS2_k127_59974_3 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
REGS2_k127_59974_4 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001228 274.0
REGS2_k127_59974_5 alcohol dehydrogenase K00001,K00004,K00098 - 1.1.1.1,1.1.1.264,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000001137 205.0
REGS2_k127_59974_6 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000001945 166.0
REGS2_k127_59974_7 protein targeting to lysosome K20191 - - 0.0001259 47.0
REGS2_k127_6040091_0 Belongs to the ClpA ClpB family K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1174.0
REGS2_k127_6040091_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000392 263.0
REGS2_k127_6040091_2 Membrane protein, TerC - - - 0.000000000000000000000000000000000000000000002125 174.0
REGS2_k127_6040091_3 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000002129 98.0
REGS2_k127_6040091_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000004825 76.0
REGS2_k127_6055759_0 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002344 290.0
REGS2_k127_6055759_1 DinB family - - - 0.0000000000000000000000000000000000000000004392 164.0
REGS2_k127_6055759_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000004259 113.0
REGS2_k127_6055759_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000005479 114.0
REGS2_k127_6055759_4 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.00000000000005417 76.0
REGS2_k127_6055759_5 - - - - 0.000000002332 64.0
REGS2_k127_6057680_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 560.0
REGS2_k127_6057680_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 458.0
REGS2_k127_6057680_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000003144 229.0
REGS2_k127_6057680_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001638 240.0
REGS2_k127_6057680_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000001204 225.0
REGS2_k127_6057680_13 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000006895 214.0
REGS2_k127_6057680_14 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000006517 156.0
REGS2_k127_6057680_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000001322 153.0
REGS2_k127_6057680_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000003301 146.0
REGS2_k127_6057680_17 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000000000000000000000001584 135.0
REGS2_k127_6057680_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000002976 114.0
REGS2_k127_6057680_19 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000001599 108.0
REGS2_k127_6057680_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 399.0
REGS2_k127_6057680_20 - - - - 0.000000000000000003633 89.0
REGS2_k127_6057680_21 - - - - 0.00000415 51.0
REGS2_k127_6057680_22 Predicted membrane protein (DUF2085) - - - 0.00001069 55.0
REGS2_k127_6057680_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 353.0
REGS2_k127_6057680_4 GTPase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 329.0
REGS2_k127_6057680_5 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 337.0
REGS2_k127_6057680_6 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
REGS2_k127_6057680_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 291.0
REGS2_k127_6057680_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002248 286.0
REGS2_k127_6057680_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003266 285.0
REGS2_k127_6058202_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 541.0
REGS2_k127_6058202_1 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 530.0
REGS2_k127_6058202_2 aminopeptidase activity K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 388.0
REGS2_k127_6063767_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 578.0
REGS2_k127_6063767_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007744 253.0
REGS2_k127_6063767_2 PFAM PEGA domain - - - 0.000000000004819 79.0
REGS2_k127_6063767_3 energy transducer activity K03832,K07126 - - 0.00002562 55.0
REGS2_k127_6063767_4 Family membership - - - 0.00002596 57.0
REGS2_k127_6063767_5 WD domain, G-beta repeat - - - 0.0003316 52.0
REGS2_k127_6076703_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 3.385e-267 827.0
REGS2_k127_6076703_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 611.0
REGS2_k127_6076703_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 436.0
REGS2_k127_6076703_3 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 399.0
REGS2_k127_6076703_4 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 380.0
REGS2_k127_6076703_5 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000000002631 190.0
REGS2_k127_6076703_6 PaaD-like protein - - - 0.0000000000000000000000000000000006283 134.0
REGS2_k127_6076703_7 Transcriptional regulator - - - 0.0000000000000000000000446 103.0
REGS2_k127_6076703_8 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000006068 104.0
REGS2_k127_6080884_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 3.036e-253 799.0
REGS2_k127_6080884_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000004229 170.0
REGS2_k127_6080884_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000003586 103.0
REGS2_k127_6080884_3 Transcriptional regulator PadR-like family - - - 0.0000000003495 62.0
REGS2_k127_6116031_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001632 289.0
REGS2_k127_6116031_1 von Willebrand factor, type A K12511 - - 0.0000000000000000000000000000000000000000000000000009335 194.0
REGS2_k127_6116031_2 - - - - 0.000000000000000000000000000000000000000000000000001467 191.0
REGS2_k127_6116031_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000004805 158.0
REGS2_k127_6116031_4 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000008566 156.0
REGS2_k127_6116031_5 YtxH-like protein - - - 0.0002481 49.0
REGS2_k127_6116031_6 repeat-containing protein - - - 0.0005426 49.0
REGS2_k127_6133129_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0007183 52.0
REGS2_k127_6138008_0 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 310.0
REGS2_k127_6138008_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000001961 158.0
REGS2_k127_6138008_2 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000123 124.0
REGS2_k127_6138008_3 Beta-lactamase superfamily domain - - - 0.0000000000000003571 81.0
REGS2_k127_6138008_4 - - - - 0.00001226 56.0
REGS2_k127_6176181_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 501.0
REGS2_k127_6176181_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 364.0
REGS2_k127_6176181_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000002409 65.0
REGS2_k127_6176181_3 23S rRNA-intervening sequence protein - - - 0.00007121 54.0
REGS2_k127_6186090_0 MacB-like periplasmic core domain - - - 2.747e-320 999.0
REGS2_k127_6186090_1 PFAM Ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 541.0
REGS2_k127_6186090_2 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000008287 57.0
REGS2_k127_6188790_0 peptidase activity K06889 - - 0.000000000000000000000000000000000001682 151.0
REGS2_k127_6191466_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.056e-263 819.0
REGS2_k127_6191466_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 436.0
REGS2_k127_6191466_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 413.0
REGS2_k127_6191466_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 406.0
REGS2_k127_6191466_4 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 360.0
REGS2_k127_6191466_5 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
REGS2_k127_6191466_6 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000346 276.0
REGS2_k127_6191466_7 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 265.0
REGS2_k127_6191466_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000001993 95.0
REGS2_k127_6198471_0 COGs COG1740 Ni Fe-hydrogenase I small subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 534.0
REGS2_k127_6198471_1 COGs COG0374 Ni Fe-hydrogenase I large subunit K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 352.0
REGS2_k127_6198471_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001069 279.0
REGS2_k127_6218624_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1277.0
REGS2_k127_6218624_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 591.0
REGS2_k127_6218624_2 Pfam Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 339.0
REGS2_k127_6218624_3 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 304.0
REGS2_k127_6229948_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1534.0
REGS2_k127_6229948_1 E1-E2 ATPase K01533 - 3.6.3.4 8.231e-274 858.0
REGS2_k127_6229948_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 392.0
REGS2_k127_6229948_3 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 306.0
REGS2_k127_6229948_4 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 295.0
REGS2_k127_6229948_5 aerobic electron transport chain K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000006286 200.0
REGS2_k127_6229948_6 Tetratricopeptide repeat - - - 0.00000000000000000000001855 108.0
REGS2_k127_6229948_7 Cytochrome c554 and c-prime - - - 0.00000000000000002678 87.0
REGS2_k127_6248045_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 9.11e-215 688.0
REGS2_k127_6248045_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 599.0
REGS2_k127_6248045_10 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 345.0
REGS2_k127_6248045_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 347.0
REGS2_k127_6248045_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002213 294.0
REGS2_k127_6248045_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006868 294.0
REGS2_k127_6248045_14 diguanylate cyclase - - - 0.00000000000005584 83.0
REGS2_k127_6248045_15 PFAM heat shock protein DnaJ domain protein - - - 0.0000000002692 72.0
REGS2_k127_6248045_16 Peptidase M56 - - - 0.000000001341 70.0
REGS2_k127_6248045_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 563.0
REGS2_k127_6248045_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 525.0
REGS2_k127_6248045_4 Type II IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 498.0
REGS2_k127_6248045_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 467.0
REGS2_k127_6248045_6 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 460.0
REGS2_k127_6248045_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 417.0
REGS2_k127_6248045_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 359.0
REGS2_k127_6248045_9 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 361.0
REGS2_k127_6257599_0 amino acid - - - 4.24e-249 784.0
REGS2_k127_6257599_1 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 5.31e-220 702.0
REGS2_k127_6257599_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.000000000000000001566 86.0
REGS2_k127_6269790_0 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 555.0
REGS2_k127_6269790_1 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 496.0
REGS2_k127_6269790_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000005094 148.0
REGS2_k127_6269790_11 Putative adhesin - - - 0.0000000000000000000000000000002347 136.0
REGS2_k127_6269790_12 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000009972 87.0
REGS2_k127_6269790_13 - - - - 0.000000000000003545 85.0
REGS2_k127_6269790_14 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000839 68.0
REGS2_k127_6269790_15 Response regulator, receiver K07677,K07679,K20974 - 2.7.13.3 0.0000003651 58.0
REGS2_k127_6269790_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 477.0
REGS2_k127_6269790_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 413.0
REGS2_k127_6269790_4 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
REGS2_k127_6269790_5 peptidoglycan glycosyltransferase activity K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 294.0
REGS2_k127_6269790_6 Fungalysin/Thermolysin Propeptide Motif K08603 - 3.4.24.27 0.00000000000000000000000000000000000000000000000000000000000000000000008171 260.0
REGS2_k127_6269790_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000003648 198.0
REGS2_k127_6269790_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000005488 153.0
REGS2_k127_6269790_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000004934 149.0
REGS2_k127_6290601_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.224e-229 722.0
REGS2_k127_6290601_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 514.0
REGS2_k127_6290601_2 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 439.0
REGS2_k127_6290601_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 395.0
REGS2_k127_6290601_4 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007269 269.0
REGS2_k127_6290601_5 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000216 245.0
REGS2_k127_6290601_6 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001172 213.0
REGS2_k127_6290601_7 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000001373 165.0
REGS2_k127_6290601_8 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000002348 160.0
REGS2_k127_6290601_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000083 91.0
REGS2_k127_6310096_0 transmembrane transporter activity K03296 - - 5.663e-229 741.0
REGS2_k127_6310096_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0002274 44.0
REGS2_k127_6317837_0 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 431.0
REGS2_k127_6317837_1 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
REGS2_k127_6317837_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001375 278.0
REGS2_k127_6317837_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000452 282.0
REGS2_k127_6317837_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000003498 172.0
REGS2_k127_6317837_5 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000001935 113.0
REGS2_k127_6317837_6 Glutaredoxin - - - 0.000000002415 60.0
REGS2_k127_6326970_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 385.0
REGS2_k127_6326970_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001106 237.0
REGS2_k127_6326970_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000005776 189.0
REGS2_k127_6346675_0 Radical SAM - - - 0.0 1122.0
REGS2_k127_6346675_1 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.509e-227 738.0
REGS2_k127_6346675_10 histidine kinase A domain protein - - - 0.00000000008296 71.0
REGS2_k127_6346675_11 cellulase activity K01181 - 3.2.1.8 0.0001057 51.0
REGS2_k127_6346675_2 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 437.0
REGS2_k127_6346675_3 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 426.0
REGS2_k127_6346675_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
REGS2_k127_6346675_5 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005383 268.0
REGS2_k127_6346675_6 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000005749 217.0
REGS2_k127_6346675_7 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000001672 139.0
REGS2_k127_6346675_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000545 130.0
REGS2_k127_6357211_0 amine dehydrogenase activity - - - 1.038e-259 838.0
REGS2_k127_6357211_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 617.0
REGS2_k127_6357211_2 Protease prsW family - - - 0.00000000000000000000000000002877 129.0
REGS2_k127_6370819_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.985e-258 802.0
REGS2_k127_6370819_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.511e-258 809.0
REGS2_k127_6370819_2 PFAM glycoside hydrolase 15-related K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 310.0
REGS2_k127_6391750_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 432.0
REGS2_k127_6391750_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 443.0
REGS2_k127_6391750_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 400.0
REGS2_k127_6391750_3 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 299.0
REGS2_k127_6391750_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003188 279.0
REGS2_k127_6391750_5 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000004549 265.0
REGS2_k127_6391750_6 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000002025 207.0
REGS2_k127_6391750_7 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000002684 196.0
REGS2_k127_6391750_8 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000003116 110.0
REGS2_k127_6399226_0 Glutamine synthetase type III K01915 - 6.3.1.2 6.397e-312 974.0
REGS2_k127_6399226_1 radical SAM domain protein - - - 2.131e-203 645.0
REGS2_k127_6399226_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004817 240.0
REGS2_k127_6399226_3 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000001062 241.0
REGS2_k127_6399226_4 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit K02469 - 5.99.1.3 0.0000000000000000000001459 99.0
REGS2_k127_6431786_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 596.0
REGS2_k127_6431786_1 NADP Oxidoreductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 359.0
REGS2_k127_6476819_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 286.0
REGS2_k127_6476819_1 [2Fe-2S] binding domain K07302,K13483 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002718 256.0
REGS2_k127_6485815_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 368.0
REGS2_k127_6485815_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
REGS2_k127_6485815_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000003018 58.0
REGS2_k127_6490358_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 5.489e-199 631.0
REGS2_k127_6490358_1 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 309.0
REGS2_k127_6490358_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000408 189.0
REGS2_k127_6490358_3 RND efflux system, outer membrane lipoprotein K18139 - - 0.000004044 55.0
REGS2_k127_6506911_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 443.0
REGS2_k127_6506911_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 439.0
REGS2_k127_6506911_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 313.0
REGS2_k127_6506911_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000018 129.0
REGS2_k127_6508915_0 Domain of unknown function (DUF1998) K06877 - - 7.325e-256 813.0
REGS2_k127_6508915_1 Sodium:alanine symporter family K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 559.0
REGS2_k127_6508915_2 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000007607 206.0
REGS2_k127_6508915_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002701 113.0
REGS2_k127_6508915_4 Protein of unknown function (DUF1569) - - - 0.000000000000000000000009138 115.0
REGS2_k127_6508915_5 PFAM aldo keto reductase - - - 0.00000000000394 66.0
REGS2_k127_6534115_0 Succinyl-CoA ligase like flavodoxin domain - - - 7.495e-259 827.0
REGS2_k127_6534115_1 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 558.0
REGS2_k127_6534115_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 476.0
REGS2_k127_6534115_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 321.0
REGS2_k127_6534115_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 294.0
REGS2_k127_6534115_5 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000004679 146.0
REGS2_k127_6534115_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.0000000000000000001463 94.0
REGS2_k127_6534115_7 NifU-like domain - - - 0.0000000000000001864 82.0
REGS2_k127_6534115_8 negative regulation of growth - - - 0.0000000000005972 70.0
REGS2_k127_6534115_9 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.00000023 55.0
REGS2_k127_6537484_0 radical SAM domain protein K22318 - - 1.13e-229 723.0
REGS2_k127_6537484_1 acetyl-CoA hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 476.0
REGS2_k127_6537484_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 388.0
REGS2_k127_6537484_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000003427 171.0
REGS2_k127_6549539_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 562.0
REGS2_k127_6549539_1 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 509.0
REGS2_k127_6549539_2 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 323.0
REGS2_k127_6549539_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 339.0
REGS2_k127_6549539_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002201 290.0
REGS2_k127_6549539_5 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000001603 97.0
REGS2_k127_6549539_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.00001744 53.0
REGS2_k127_6672113_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 0.000000000000000000000000000000000000000000000000000776 188.0
REGS2_k127_6672113_1 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.000000000001481 79.0
REGS2_k127_6672113_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0002548 53.0
REGS2_k127_6677552_0 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 307.0
REGS2_k127_6677552_1 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000000000000000061 207.0
REGS2_k127_6677552_2 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000001167 158.0
REGS2_k127_6774067_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000137 193.0
REGS2_k127_6774067_1 - - - - 0.0000000000000000001185 93.0
REGS2_k127_6774067_2 Radical SAM domain protein - - - 0.000000000000000009738 87.0
REGS2_k127_6774067_3 SNARE associated Golgi protein - - - 0.00000002259 64.0
REGS2_k127_6803039_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000001897 228.0
REGS2_k127_6803039_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000001412 188.0
REGS2_k127_6803039_2 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000728 66.0
REGS2_k127_6803039_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000001104 61.0
REGS2_k127_6810561_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 1.711e-214 689.0
REGS2_k127_6810561_1 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000001956 246.0
REGS2_k127_68790_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.001e-265 841.0
REGS2_k127_68790_1 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 395.0
REGS2_k127_68790_2 unfolded protein binding K06142 - - 0.000000000003755 75.0
REGS2_k127_68790_3 Lytic murein transglycosylase - - - 0.0000000007877 64.0
REGS2_k127_6897177_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 2.335e-221 708.0
REGS2_k127_6897177_1 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 542.0
REGS2_k127_6897177_10 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000002294 176.0
REGS2_k127_6897177_11 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000002917 173.0
REGS2_k127_6897177_12 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000002927 101.0
REGS2_k127_6897177_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000003604 57.0
REGS2_k127_6897177_14 efflux transmembrane transporter activity - - - 0.0000007159 52.0
REGS2_k127_6897177_15 hmm pf04305 - - - 0.0007058 43.0
REGS2_k127_6897177_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 509.0
REGS2_k127_6897177_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 521.0
REGS2_k127_6897177_4 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 471.0
REGS2_k127_6897177_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 481.0
REGS2_k127_6897177_6 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 403.0
REGS2_k127_6897177_7 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 334.0
REGS2_k127_6897177_8 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000001302 208.0
REGS2_k127_6897177_9 Membrane - - - 0.000000000000000000000000000000000000000000000003323 188.0
REGS2_k127_6901917_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 385.0
REGS2_k127_6905625_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 560.0
REGS2_k127_6905625_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 378.0
REGS2_k127_6905625_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 353.0
REGS2_k127_6905625_3 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006553 293.0
REGS2_k127_6905625_4 Single Cache domain 2 K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000002701 238.0
REGS2_k127_6905625_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000002778 207.0
REGS2_k127_6905625_6 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000447 202.0
REGS2_k127_6905625_7 - - - - 0.0000000000000000000000000000000000001681 158.0
REGS2_k127_6905625_9 GtrA-like protein - - - 0.0000000000000006094 83.0
REGS2_k127_6906232_0 aminopeptidase activity K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 476.0
REGS2_k127_6906232_1 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000164 214.0
REGS2_k127_6910598_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 557.0
REGS2_k127_6910598_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 362.0
REGS2_k127_6910598_10 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000001115 162.0
REGS2_k127_6910598_11 membrane - - - 0.00000000000000000000000000000000000000002648 161.0
REGS2_k127_6910598_12 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000000000000005 146.0
REGS2_k127_6910598_13 domain protein - - - 0.000000000000000000000000000000000009492 155.0
REGS2_k127_6910598_14 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000003278 137.0
REGS2_k127_6910598_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000009934 124.0
REGS2_k127_6910598_16 - - - - 0.0000000000000000002424 91.0
REGS2_k127_6910598_17 - - - - 0.00000000000000003649 82.0
REGS2_k127_6910598_18 helix_turn_helix isocitrate lyase regulation K13641 - - 0.0000000000000007687 87.0
REGS2_k127_6910598_19 - - - - 0.000000000000003315 88.0
REGS2_k127_6910598_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 355.0
REGS2_k127_6910598_21 AntiSigma factor - - - 0.00000006015 63.0
REGS2_k127_6910598_22 Peptidase family M28 - - - 0.0000004285 63.0
REGS2_k127_6910598_23 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00000468 54.0
REGS2_k127_6910598_24 Aspartyl protease - - - 0.0001067 55.0
REGS2_k127_6910598_3 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
REGS2_k127_6910598_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005348 269.0
REGS2_k127_6910598_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003269 256.0
REGS2_k127_6910598_6 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000007842 225.0
REGS2_k127_6910598_7 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000003184 177.0
REGS2_k127_6910598_8 - - - - 0.0000000000000000000000000000000000000000000003926 175.0
REGS2_k127_6910598_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000001075 162.0
REGS2_k127_6911664_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 1.412e-287 904.0
REGS2_k127_6911664_1 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 3.991e-247 796.0
REGS2_k127_6911664_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 471.0
REGS2_k127_6911664_3 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000005934 204.0
REGS2_k127_6911664_4 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000001126 201.0
REGS2_k127_6911664_5 - - - - 0.0000000000000000000000000000000000000000001355 165.0
REGS2_k127_6911664_6 PFAM TfoX N-terminal domain K07343 - - 0.000000000000000000000000007647 115.0
REGS2_k127_6914026_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.73e-263 822.0
REGS2_k127_6914026_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.076e-218 684.0
REGS2_k127_6914026_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 469.0
REGS2_k127_6914026_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 456.0
REGS2_k127_6914026_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 373.0
REGS2_k127_6914026_5 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002939 265.0
REGS2_k127_6914026_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000008236 209.0
REGS2_k127_6914026_7 Tetratricopeptide repeat - - - 0.000000000000000005598 92.0
REGS2_k127_6914026_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000002806 56.0
REGS2_k127_6914173_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.252e-209 681.0
REGS2_k127_6914173_1 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 526.0
REGS2_k127_6914173_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000001318 170.0
REGS2_k127_6914173_3 Plasmid stability protein K21495 - - 0.00000000001872 67.0
REGS2_k127_6914173_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000004744 70.0
REGS2_k127_6919198_0 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000000000008021 113.0
REGS2_k127_6919198_1 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000001972 105.0
REGS2_k127_6919198_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000001363 81.0
REGS2_k127_6919198_3 Belongs to the peptidase S8 family - - - 0.0000005991 65.0
REGS2_k127_6919911_0 cellulose binding - - - 0.0 1067.0
REGS2_k127_6919911_1 FtsX-like permease family - - - 2.774e-232 747.0
REGS2_k127_6919911_2 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 332.0
REGS2_k127_6920947_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 510.0
REGS2_k127_6920947_1 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 329.0
REGS2_k127_6920947_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000003598 227.0
REGS2_k127_6920947_3 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000006745 123.0
REGS2_k127_6920947_4 PLD-like domain - - - 0.000579 49.0
REGS2_k127_6924463_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 1.891e-299 945.0
REGS2_k127_6924463_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 492.0
REGS2_k127_6924463_2 polysaccharide catabolic process K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000006539 210.0
REGS2_k127_6924463_3 pfam rok - - - 0.000000000000000000000000000000000000000000000007898 187.0
REGS2_k127_6927308_0 serine-type peptidase activity K08676 - - 0.0 1284.0
REGS2_k127_6927308_1 Carboxypeptidase regulatory-like domain - - - 0.0 1060.0
REGS2_k127_6927308_10 - - - - 0.000000000000000000000000000000000000000000001022 175.0
REGS2_k127_6927308_11 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000004534 129.0
REGS2_k127_6927308_12 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000004855 86.0
REGS2_k127_6927308_13 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000002418 80.0
REGS2_k127_6927308_14 - - - - 0.0000000001828 69.0
REGS2_k127_6927308_15 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000008413 57.0
REGS2_k127_6927308_16 SMART protein phosphatase 2C domain protein - - - 0.000007294 54.0
REGS2_k127_6927308_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 521.0
REGS2_k127_6927308_3 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 498.0
REGS2_k127_6927308_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 496.0
REGS2_k127_6927308_5 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 388.0
REGS2_k127_6927308_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005497 278.0
REGS2_k127_6927308_7 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002471 257.0
REGS2_k127_6927308_8 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000003326 224.0
REGS2_k127_6927308_9 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000006424 210.0
REGS2_k127_6928626_0 serine-type peptidase activity - - - 4.374e-256 820.0
REGS2_k127_6928626_1 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 440.0
REGS2_k127_6928626_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000006091 112.0
REGS2_k127_6928626_3 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000009281 83.0
REGS2_k127_6928626_4 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000001422 54.0
REGS2_k127_6929729_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 1.134e-215 678.0
REGS2_k127_6929729_1 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 427.0
REGS2_k127_6929729_10 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000001414 156.0
REGS2_k127_6929729_11 4Fe-4S binding domain - - - 0.000000000000000000000000000002297 124.0
REGS2_k127_6929729_12 Methanol dehydrogenase K06872 - - 0.0000000000000000000000000006669 129.0
REGS2_k127_6929729_13 nucleotidyltransferase activity - - - 0.000000000000000000000001845 112.0
REGS2_k127_6929729_14 - - - - 0.00002556 57.0
REGS2_k127_6929729_2 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 421.0
REGS2_k127_6929729_3 Serine aminopeptidase, S33 K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 295.0
REGS2_k127_6929729_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003271 259.0
REGS2_k127_6929729_5 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000003883 214.0
REGS2_k127_6929729_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
REGS2_k127_6929729_7 Uncharacterised protein family UPF0052 - - - 0.000000000000000000000000000000000000000000000000001259 198.0
REGS2_k127_6929729_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000004244 198.0
REGS2_k127_6929729_9 DinB family - - - 0.0000000000000000000000000000000000000000002881 166.0
REGS2_k127_6931614_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 0.0 1245.0
REGS2_k127_6931614_1 Glutaryl-7-ACA acylase K06978 - - 4.12e-321 993.0
REGS2_k127_6931614_2 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 586.0
REGS2_k127_6931614_3 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000005506 142.0
REGS2_k127_6931614_4 Beta-lactamase - - - 0.0007204 44.0
REGS2_k127_6943236_0 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 2.48e-258 814.0
REGS2_k127_6944533_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 310.0
REGS2_k127_6944533_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000003326 224.0
REGS2_k127_6944533_10 general secretion pathway protein K02456,K02650 - - 0.0000181 55.0
REGS2_k127_6944533_2 - - - - 0.00000000000000000000000000000000000000000000000000001368 205.0
REGS2_k127_6944533_3 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000004896 204.0
REGS2_k127_6944533_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000001222 164.0
REGS2_k127_6944533_5 Thioredoxin - - - 0.000000000000007183 87.0
REGS2_k127_6944533_6 Pfam:N_methyl_2 - - - 0.000000001037 65.0
REGS2_k127_6944533_7 VKc - - - 0.0000009178 61.0
REGS2_k127_6944533_8 Type IV Pilus-assembly protein W K02672 - - 0.000001102 61.0
REGS2_k127_6944533_9 Type II transport protein GspH K08084 - - 0.000009836 55.0
REGS2_k127_6947764_0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 479.0
REGS2_k127_6947764_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 320.0
REGS2_k127_6947764_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008907 247.0
REGS2_k127_6947764_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000004693 202.0
REGS2_k127_6947764_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000001457 165.0
REGS2_k127_6947764_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000003089 141.0
REGS2_k127_6947764_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000002164 89.0
REGS2_k127_6947764_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000009802 61.0
REGS2_k127_6960195_0 lysine biosynthetic process via aminoadipic acid - - - 2.063e-244 778.0
REGS2_k127_6960195_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 303.0
REGS2_k127_6960195_2 von Willebrand factor, type A - - - 0.0000000000000000000000000000006828 136.0
REGS2_k127_6960195_3 oxidoreductase activity - - - 0.000000005087 70.0
REGS2_k127_6961553_0 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.377e-200 636.0
REGS2_k127_6961553_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 476.0
REGS2_k127_6961553_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 320.0
REGS2_k127_6961553_3 S23 ribosomal protein - - - 0.000000000791 66.0
REGS2_k127_6961553_4 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000005707 57.0
REGS2_k127_6970019_0 Dienelactone hydrolase family - - - 1.912e-239 760.0
REGS2_k127_6970019_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 628.0
REGS2_k127_6970019_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 482.0
REGS2_k127_6970019_3 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 471.0
REGS2_k127_6970019_4 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 370.0
REGS2_k127_6970019_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009732 269.0
REGS2_k127_6970019_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000462 109.0
REGS2_k127_6970019_7 Protein conserved in bacteria K15539 - - 0.0000000002854 69.0
REGS2_k127_6970019_9 Transmembrane secretion effector - - - 0.0001025 46.0
REGS2_k127_6979789_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 428.0
REGS2_k127_6979789_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000004021 127.0
REGS2_k127_6979789_2 PFAM PEGA domain - - - 0.000000000000000000004473 108.0
REGS2_k127_6979789_3 Amino-transferase class IV K02619 - 4.1.3.38 0.000000003667 59.0
REGS2_k127_6979789_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000006291 57.0
REGS2_k127_6983091_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 605.0
REGS2_k127_6983091_1 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 548.0
REGS2_k127_6983091_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000007296 181.0
REGS2_k127_6983091_11 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000005729 173.0
REGS2_k127_6983091_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000001468 160.0
REGS2_k127_6983091_13 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000002608 144.0
REGS2_k127_6983091_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000007418 139.0
REGS2_k127_6983091_15 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000003805 104.0
REGS2_k127_6983091_17 PKD domain containing protein - - - 0.000000000000000003013 94.0
REGS2_k127_6983091_18 Tetratricopeptide repeats - - - 0.00000000006261 71.0
REGS2_k127_6983091_19 Fimbrial assembly protein (PilN) K02663 - - 0.000000001927 70.0
REGS2_k127_6983091_2 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 373.0
REGS2_k127_6983091_20 Pilus assembly protein, PilP K02665 - - 0.00006153 53.0
REGS2_k127_6983091_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 347.0
REGS2_k127_6983091_4 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 337.0
REGS2_k127_6983091_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 311.0
REGS2_k127_6983091_6 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 297.0
REGS2_k127_6983091_7 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000004015 240.0
REGS2_k127_6983091_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000006544 178.0
REGS2_k127_6983091_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000001704 179.0
REGS2_k127_6988571_0 Major Facilitator Superfamily K02445,K07783 - - 2.239e-217 694.0
REGS2_k127_6988571_1 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 527.0
REGS2_k127_6988571_2 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 409.0
REGS2_k127_6988571_3 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 386.0
REGS2_k127_6988571_4 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 373.0
REGS2_k127_6991859_0 ATPase BadF BadG BcrA BcrD type - - - 1.689e-303 962.0
REGS2_k127_6991859_1 4Fe-4S single cluster domain K06937 - - 6.734e-222 704.0
REGS2_k127_6991859_10 MMPL family K07003 - - 0.000000002269 63.0
REGS2_k127_6991859_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 450.0
REGS2_k127_6991859_3 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 420.0
REGS2_k127_6991859_4 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 372.0
REGS2_k127_6991859_5 Histidine ammonia-lyase K01745,K10774 GO:0003674,GO:0003824,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016866,GO:0016869,GO:0050368 4.3.1.23,4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 365.0
REGS2_k127_6991859_6 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.000000000000000000000000000000000169 149.0
REGS2_k127_6991859_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000334 141.0
REGS2_k127_6991859_8 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000007049 104.0
REGS2_k127_6991859_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000001682 89.0
REGS2_k127_7017277_0 Thiolase, C-terminal domain - - - 8.133e-197 619.0
REGS2_k127_7017277_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 603.0
REGS2_k127_7017277_10 Alpha/beta hydrolase family - - - 0.000000000000000003191 95.0
REGS2_k127_7017277_11 Bacterial regulatory proteins, tetR family - - - 0.00000000001362 74.0
REGS2_k127_7017277_2 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 570.0
REGS2_k127_7017277_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 483.0
REGS2_k127_7017277_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 476.0
REGS2_k127_7017277_5 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 306.0
REGS2_k127_7017277_6 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 299.0
REGS2_k127_7017277_7 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001172 278.0
REGS2_k127_7017277_8 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000005347 144.0
REGS2_k127_7017277_9 Alpha beta hydrolase K01055,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000001312 122.0
REGS2_k127_7022504_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.838e-235 740.0
REGS2_k127_7022504_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
REGS2_k127_7022504_2 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000009009 194.0
REGS2_k127_7022504_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000008595 158.0
REGS2_k127_7024985_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 604.0
REGS2_k127_7024985_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 316.0
REGS2_k127_7024985_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000608 137.0
REGS2_k127_7024985_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000001089 78.0
REGS2_k127_7024985_12 Ribosomal protein L30p/L7e K02907 - - 0.0000000000001084 72.0
REGS2_k127_7024985_13 Ribosomal protein L36 K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002067 66.0
REGS2_k127_7024985_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 320.0
REGS2_k127_7024985_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 286.0
REGS2_k127_7024985_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000001408 216.0
REGS2_k127_7024985_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000001558 194.0
REGS2_k127_7024985_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000004374 182.0
REGS2_k127_7024985_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000003265 175.0
REGS2_k127_7024985_8 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001303 173.0
REGS2_k127_7024985_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000002601 139.0
REGS2_k127_7026087_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 578.0
REGS2_k127_7026087_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 352.0
REGS2_k127_7026087_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 300.0
REGS2_k127_7026087_3 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000007437 203.0
REGS2_k127_7026087_4 Diaminopimelate epimerase K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000003611 184.0
REGS2_k127_7026087_5 Nodulation protein S (NodS) K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000008783 125.0
REGS2_k127_7030483_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 555.0
REGS2_k127_7030483_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 351.0
REGS2_k127_7030483_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
REGS2_k127_7030483_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 289.0
REGS2_k127_7030483_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000003222 78.0
REGS2_k127_7030483_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00004519 48.0
REGS2_k127_7036030_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 372.0
REGS2_k127_7036030_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000002706 109.0
REGS2_k127_7036030_2 Amino acid permease - - - 0.00000000000000002687 83.0
REGS2_k127_7041104_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 4.384e-258 834.0
REGS2_k127_7041104_1 PFAM Enoyl-CoA hydratase isomerase - - - 4.863e-216 692.0
REGS2_k127_7041104_10 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000001003 61.0
REGS2_k127_7041104_2 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 617.0
REGS2_k127_7041104_3 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 481.0
REGS2_k127_7041104_4 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 442.0
REGS2_k127_7041104_5 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 426.0
REGS2_k127_7041104_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 308.0
REGS2_k127_7041104_7 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K18021 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.5.3,1.2.99.8 0.0000000000000000000000000000000000000000000000006269 187.0
REGS2_k127_7041104_8 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000001487 184.0
REGS2_k127_7041104_9 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000841 136.0
REGS2_k127_7043360_0 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000003134 157.0
REGS2_k127_7043360_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000001509 119.0
REGS2_k127_7043360_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000002507 98.0
REGS2_k127_7043360_3 Tetratricopeptide repeat - - - 0.0005567 52.0
REGS2_k127_7051237_0 Sodium:solute symporter family K03307 - - 1.702e-228 719.0
REGS2_k127_7051237_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 556.0
REGS2_k127_7051237_2 - - - - 0.00000000000457 68.0
REGS2_k127_7051237_3 Glycosyl hydrolase family 63 C-terminal domain K03931 - - 0.00001183 49.0
REGS2_k127_7086897_0 4Fe-4S dicluster domain - - - 0.0 1223.0
REGS2_k127_7086897_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 6.892e-202 637.0
REGS2_k127_7086897_10 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
REGS2_k127_7086897_11 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004402 261.0
REGS2_k127_7086897_12 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000003968 228.0
REGS2_k127_7086897_13 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
REGS2_k127_7086897_14 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000503 210.0
REGS2_k127_7086897_15 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000003096 131.0
REGS2_k127_7086897_16 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000007814 130.0
REGS2_k127_7086897_17 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000001549 63.0
REGS2_k127_7086897_18 spectrin binding K15502,K15503,K16717 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013 - 0.000000003289 68.0
REGS2_k127_7086897_19 Glycogen debranching enzyme N terminal - - - 0.0000003037 53.0
REGS2_k127_7086897_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 531.0
REGS2_k127_7086897_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 460.0
REGS2_k127_7086897_4 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 427.0
REGS2_k127_7086897_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 385.0
REGS2_k127_7086897_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 370.0
REGS2_k127_7086897_7 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 340.0
REGS2_k127_7086897_8 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 264.0
REGS2_k127_7086897_9 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000004583 260.0
REGS2_k127_7106813_0 MacB-like periplasmic core domain - - - 4.358e-317 990.0
REGS2_k127_7106813_1 Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE K07306 - 1.8.5.3 6.751e-233 743.0
REGS2_k127_7106813_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07307 - - 0.000000000000000000000000000000000000000000000000000000000000000529 238.0
REGS2_k127_7106813_11 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001099 238.0
REGS2_k127_7106813_12 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000004605 211.0
REGS2_k127_7106813_13 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000000001412 199.0
REGS2_k127_7106813_14 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000002483 196.0
REGS2_k127_7106813_15 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000008697 192.0
REGS2_k127_7106813_16 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000656 194.0
REGS2_k127_7106813_17 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001161 168.0
REGS2_k127_7106813_18 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000002538 148.0
REGS2_k127_7106813_19 DinB family - - - 0.00000000000000000000000000002015 124.0
REGS2_k127_7106813_2 (ABC) transporter K06147,K18890 - - 1.981e-206 658.0
REGS2_k127_7106813_20 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000007349 109.0
REGS2_k127_7106813_21 Oxidoreductase domain protein - - - 0.00000000000000000004875 91.0
REGS2_k127_7106813_22 Belongs to the 'phage' integrase family - - - 0.00000000000000001718 91.0
REGS2_k127_7106813_23 Cold shock protein domain - - - 0.0000000000000001019 85.0
REGS2_k127_7106813_24 3D domain - - - 0.0000000000000142 82.0
REGS2_k127_7106813_25 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000005768 81.0
REGS2_k127_7106813_26 nuclear chromosome segregation - - - 0.0000000001116 74.0
REGS2_k127_7106813_29 Psort location Cytoplasmic, score - - - 0.000776 48.0
REGS2_k127_7106813_3 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 574.0
REGS2_k127_7106813_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 552.0
REGS2_k127_7106813_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 479.0
REGS2_k127_7106813_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 392.0
REGS2_k127_7106813_7 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008159 267.0
REGS2_k127_7106813_8 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002876 280.0
REGS2_k127_7106813_9 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003098 257.0
REGS2_k127_7135298_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 5.957e-234 744.0
REGS2_k127_7135298_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 413.0
REGS2_k127_7135298_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
REGS2_k127_7135298_3 imidazolonepropionase activity K15358 - 3.5.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001521 284.0
REGS2_k127_7142805_0 Protein of unknown function, DUF255 K06888 - - 2.246e-212 689.0
REGS2_k127_7142805_1 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 396.0
REGS2_k127_7142805_10 - - - - 0.0001151 55.0
REGS2_k127_7142805_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
REGS2_k127_7142805_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007097 277.0
REGS2_k127_7142805_4 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 241.0
REGS2_k127_7142805_5 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000006692 247.0
REGS2_k127_7142805_6 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000003882 178.0
REGS2_k127_7142805_7 Virulence factor BrkB - - - 0.0000000000000000000008546 106.0
REGS2_k127_7142805_8 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000002222 69.0
REGS2_k127_7142805_9 YtxH-like protein - - - 0.00005735 51.0
REGS2_k127_7147819_0 amino acid K03294 - - 7.249e-210 662.0
REGS2_k127_7147819_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 310.0
REGS2_k127_7147819_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001214 241.0
REGS2_k127_7147819_3 - K01992 - - 0.0000000000004626 77.0
REGS2_k127_7159785_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 371.0
REGS2_k127_7159785_1 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 344.0
REGS2_k127_7159785_10 Belongs to the ompA family - - - 0.00000000000000000000000000000807 128.0
REGS2_k127_7159785_11 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000002591 78.0
REGS2_k127_7159785_12 PFAM Amino acid-binding ACT - - - 0.0000000001486 69.0
REGS2_k127_7159785_13 - - - - 0.000000004155 62.0
REGS2_k127_7159785_14 von Willebrand factor type A domain K07114 - - 0.0000002511 64.0
REGS2_k127_7159785_15 Endonuclease/Exonuclease/phosphatase family - - - 0.0000003691 61.0
REGS2_k127_7159785_2 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 296.0
REGS2_k127_7159785_3 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005327 287.0
REGS2_k127_7159785_4 Cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004051 259.0
REGS2_k127_7159785_5 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000000000009958 183.0
REGS2_k127_7159785_6 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000008281 178.0
REGS2_k127_7159785_7 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000002069 155.0
REGS2_k127_7159785_8 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000001474 143.0
REGS2_k127_7159785_9 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000001182 142.0
REGS2_k127_7163753_0 Phosphate acyltransferases K01897 - 6.2.1.3 4.476e-246 789.0
REGS2_k127_7163753_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.098e-226 717.0
REGS2_k127_7163753_10 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 437.0
REGS2_k127_7163753_11 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 406.0
REGS2_k127_7163753_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 411.0
REGS2_k127_7163753_13 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 393.0
REGS2_k127_7163753_14 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 379.0
REGS2_k127_7163753_15 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 344.0
REGS2_k127_7163753_16 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 332.0
REGS2_k127_7163753_17 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 327.0
REGS2_k127_7163753_18 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 320.0
REGS2_k127_7163753_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 320.0
REGS2_k127_7163753_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 497.0
REGS2_k127_7163753_20 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 319.0
REGS2_k127_7163753_21 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 314.0
REGS2_k127_7163753_22 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 303.0
REGS2_k127_7163753_23 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 299.0
REGS2_k127_7163753_24 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
REGS2_k127_7163753_25 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003619 288.0
REGS2_k127_7163753_26 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000205 280.0
REGS2_k127_7163753_27 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 270.0
REGS2_k127_7163753_28 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004555 250.0
REGS2_k127_7163753_29 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000008131 245.0
REGS2_k127_7163753_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 491.0
REGS2_k127_7163753_30 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000001506 266.0
REGS2_k127_7163753_31 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000002289 252.0
REGS2_k127_7163753_32 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000008233 240.0
REGS2_k127_7163753_33 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000001742 202.0
REGS2_k127_7163753_34 lyase activity K03301 - - 0.00000000000000000000000000000000000000000000000000001201 216.0
REGS2_k127_7163753_35 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000004535 184.0
REGS2_k127_7163753_36 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000001425 177.0
REGS2_k127_7163753_37 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000008043 160.0
REGS2_k127_7163753_38 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000001171 156.0
REGS2_k127_7163753_39 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000159 166.0
REGS2_k127_7163753_4 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 491.0
REGS2_k127_7163753_40 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000000001634 155.0
REGS2_k127_7163753_41 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000004771 154.0
REGS2_k127_7163753_42 Yqey-like protein K09117 - - 0.000000000000000000000000000000003154 138.0
REGS2_k127_7163753_43 O-linked GlcNAc transferase - - - 0.000000000000000000000000000002288 136.0
REGS2_k127_7163753_44 PAP2 superfamily - - - 0.000000000000000000000000007224 120.0
REGS2_k127_7163753_45 - - - - 0.000000000000000000000002997 113.0
REGS2_k127_7163753_46 Belongs to the GPAT DAPAT family K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 0.000000000000000000001804 107.0
REGS2_k127_7163753_47 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000001024 94.0
REGS2_k127_7163753_48 transferase activity, transferring acyl groups - - - 0.00000000000000002388 94.0
REGS2_k127_7163753_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 448.0
REGS2_k127_7163753_50 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000003924 76.0
REGS2_k127_7163753_51 Evidence 5 No homology to any previously reported sequences - - - 0.00000001946 62.0
REGS2_k127_7163753_53 Type II secretory pathway, component HofQ K02666 - - 0.0008605 49.0
REGS2_k127_7163753_6 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 453.0
REGS2_k127_7163753_7 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 449.0
REGS2_k127_7163753_8 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 455.0
REGS2_k127_7163753_9 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 445.0
REGS2_k127_7176036_0 peptidyl-tyrosine sulfation - - - 1.844e-214 687.0
REGS2_k127_7176036_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 491.0
REGS2_k127_7176036_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000002194 242.0
REGS2_k127_7179020_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 376.0
REGS2_k127_7179020_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 362.0
REGS2_k127_7179020_10 STAS domain K04749 - - 0.0000000000009271 72.0
REGS2_k127_7179020_11 PFAM Tetratricopeptide repeat - - - 0.0000004534 57.0
REGS2_k127_7179020_2 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008007 283.0
REGS2_k127_7179020_3 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000403 171.0
REGS2_k127_7179020_4 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000003494 164.0
REGS2_k127_7179020_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000003074 146.0
REGS2_k127_7179020_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000001035 135.0
REGS2_k127_7179020_7 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000004502 130.0
REGS2_k127_7179020_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000004231 110.0
REGS2_k127_7179020_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000005085 96.0
REGS2_k127_7183339_0 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000014 271.0
REGS2_k127_7183339_1 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000006404 241.0
REGS2_k127_7183339_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000008539 124.0
REGS2_k127_7183339_3 of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.000000000000000002773 85.0
REGS2_k127_7183339_4 Domain of unknown function (DUF1844) - - - 0.00000000009534 65.0
REGS2_k127_7183339_5 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0001134 46.0
REGS2_k127_7191910_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 468.0
REGS2_k127_7191910_1 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000001152 241.0
REGS2_k127_7191910_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000003458 166.0
REGS2_k127_7191910_3 CutA1 divalent ion tolerance protein K03926 - - 0.000000006668 57.0
REGS2_k127_7194403_0 Peptidase M14, carboxypeptidase A - - - 2.597e-226 714.0
REGS2_k127_7197340_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 2.833e-198 631.0
REGS2_k127_7197340_1 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000296 268.0
REGS2_k127_7197340_2 DNA-sulfur modification-associated - - - 0.000000000000000001811 97.0
REGS2_k127_7197340_3 COG3653 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000228 46.0
REGS2_k127_7206581_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 499.0
REGS2_k127_7206581_1 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 470.0
REGS2_k127_7206581_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 330.0
REGS2_k127_7206581_3 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000003611 252.0
REGS2_k127_7206581_4 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000002886 233.0
REGS2_k127_7206581_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000009458 200.0
REGS2_k127_7206581_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000636 199.0
REGS2_k127_7206581_7 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000001121 128.0
REGS2_k127_7249962_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 3.37e-202 646.0
REGS2_k127_7249962_1 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 555.0
REGS2_k127_7249962_10 phosphoesterases, related to the Icc protein - - - 0.00000000000000000000000001355 117.0
REGS2_k127_7249962_2 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 457.0
REGS2_k127_7249962_3 Histidine kinase internal region K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 335.0
REGS2_k127_7249962_4 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000009135 241.0
REGS2_k127_7249962_5 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000002829 219.0
REGS2_k127_7249962_6 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000001342 194.0
REGS2_k127_7249962_7 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000001001 188.0
REGS2_k127_7249962_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000001804 175.0
REGS2_k127_7249962_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000002808 156.0
REGS2_k127_7263618_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 569.0
REGS2_k127_7263618_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000001446 211.0
REGS2_k127_7264955_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1234.0
REGS2_k127_7264955_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 597.0
REGS2_k127_7264955_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 511.0
REGS2_k127_7264955_3 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 361.0
REGS2_k127_7265592_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.82e-259 808.0
REGS2_k127_7265592_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 536.0
REGS2_k127_7265592_10 Putative adhesin - - - 0.000000001075 70.0
REGS2_k127_7265592_11 Heat induced stress protein YflT - - - 0.00000002548 62.0
REGS2_k127_7265592_12 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00006773 51.0
REGS2_k127_7265592_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00006812 56.0
REGS2_k127_7265592_2 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 437.0
REGS2_k127_7265592_3 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 394.0
REGS2_k127_7265592_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000001432 218.0
REGS2_k127_7265592_5 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000001735 157.0
REGS2_k127_7265592_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000001149 145.0
REGS2_k127_7265592_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000003338 148.0
REGS2_k127_7265592_8 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000002458 114.0
REGS2_k127_7265592_9 Bacterial regulatory protein, Fis family - - - 0.000000000006284 72.0
REGS2_k127_7284153_0 Domain of unknown function (DUF362) - - - 1.115e-218 689.0
REGS2_k127_7284153_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 425.0
REGS2_k127_7284153_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 304.0
REGS2_k127_7284153_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000001467 184.0
REGS2_k127_7284153_4 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000000001699 146.0
REGS2_k127_7284153_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000001505 123.0
REGS2_k127_7284153_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000007953 98.0
REGS2_k127_7284153_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00009277 45.0
REGS2_k127_7311676_0 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 364.0
REGS2_k127_7311676_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 362.0
REGS2_k127_7311676_2 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000005819 235.0
REGS2_k127_7311676_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000002608 209.0
REGS2_k127_7311676_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000005582 216.0
REGS2_k127_7311676_5 PFAM Binding-protein-dependent transport K02033 - - 0.00000000000000000000000000000000000000000000000008704 188.0
REGS2_k127_7311676_6 Acetyltransferase (GNAT) domain - - - 0.00000000000003029 82.0
REGS2_k127_7366654_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 404.0
REGS2_k127_7366654_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 351.0
REGS2_k127_7366654_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 328.0
REGS2_k127_7366654_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000004081 211.0
REGS2_k127_7366654_4 protein conserved in bacteria - - - 0.00001411 55.0
REGS2_k127_7380653_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.216e-306 949.0
REGS2_k127_7380653_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000001131 223.0
REGS2_k127_7380653_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000001832 147.0
REGS2_k127_7380653_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000005335 106.0
REGS2_k127_7380653_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000001692 99.0
REGS2_k127_7380653_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000005619 96.0
REGS2_k127_7410548_0 - - - - 0.000000000000000000000000000002044 124.0
REGS2_k127_7410548_1 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000003975 120.0
REGS2_k127_7410548_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000003893 111.0
REGS2_k127_7452523_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 5.533e-259 823.0
REGS2_k127_7452523_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 430.0
REGS2_k127_7452523_10 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000008738 162.0
REGS2_k127_7452523_11 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000008798 151.0
REGS2_k127_7452523_12 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.000000000000000000000000000000000504 136.0
REGS2_k127_7452523_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000001625 113.0
REGS2_k127_7452523_14 lipopolysaccharide transport K09774 - - 0.000000000000000000000001694 120.0
REGS2_k127_7452523_15 protein trimerization - - - 0.00000000003309 74.0
REGS2_k127_7452523_16 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - 0.00000000004007 71.0
REGS2_k127_7452523_17 energy transducer activity K03646,K03832 - - 0.000000000144 71.0
REGS2_k127_7452523_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 431.0
REGS2_k127_7452523_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 406.0
REGS2_k127_7452523_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007672 364.0
REGS2_k127_7452523_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 319.0
REGS2_k127_7452523_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 302.0
REGS2_k127_7452523_7 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 295.0
REGS2_k127_7452523_8 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
REGS2_k127_7452523_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000001339 178.0
REGS2_k127_7472635_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 592.0
REGS2_k127_7472635_1 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 492.0
REGS2_k127_7472635_2 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 452.0
REGS2_k127_7472635_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 346.0
REGS2_k127_7472635_4 rRNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000779 228.0
REGS2_k127_7472635_5 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000003086 230.0
REGS2_k127_7472635_6 RNA pseudouridylate synthase K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000005096 202.0
REGS2_k127_7472635_7 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.00000000000000000000000000000001255 132.0
REGS2_k127_7472635_8 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000001034 127.0
REGS2_k127_7472635_9 helix_turn_helix, Lux Regulon - - - 0.000000000000000003229 85.0
REGS2_k127_7475035_0 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001353 279.0
REGS2_k127_7475035_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000009718 231.0
REGS2_k127_7475035_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.000000002091 60.0
REGS2_k127_7475035_3 carboxyl transferase K01969 - 6.4.1.4 0.00004023 50.0
REGS2_k127_7482669_0 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 406.0
REGS2_k127_7482669_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 389.0
REGS2_k127_7482669_2 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000993 134.0
REGS2_k127_7493114_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.053e-198 632.0
REGS2_k127_7493114_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 456.0
REGS2_k127_7493114_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 449.0
REGS2_k127_7493114_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 296.0
REGS2_k127_7493114_4 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000008262 138.0
REGS2_k127_7493114_5 Evidence 5 No homology to any previously reported sequences K09005 - - 0.0000000000000000000000002795 120.0
REGS2_k127_7493114_6 Tetratricopeptide repeat - - - 0.0000000000001196 81.0
REGS2_k127_7493114_7 Belongs to the ompA family K03286 - - 0.0002177 44.0
REGS2_k127_7541876_0 PFAM LmbE family protein K22136 - - 2.024e-277 878.0
REGS2_k127_7541876_1 PFAM Prolyl oligopeptidase family - - - 5.302e-198 640.0
REGS2_k127_7541876_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000003511 196.0
REGS2_k127_7541876_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000004864 202.0
REGS2_k127_7541876_12 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000002892 203.0
REGS2_k127_7541876_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000004119 157.0
REGS2_k127_7541876_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000101 138.0
REGS2_k127_7541876_15 FAD dependent oxidoreductase - - - 0.000000000000000000000000000003887 134.0
REGS2_k127_7541876_16 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000002599 66.0
REGS2_k127_7541876_17 endonuclease activity K07451 - - 0.00000000009075 69.0
REGS2_k127_7541876_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000005049 61.0
REGS2_k127_7541876_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 496.0
REGS2_k127_7541876_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 419.0
REGS2_k127_7541876_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 343.0
REGS2_k127_7541876_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 295.0
REGS2_k127_7541876_6 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 295.0
REGS2_k127_7541876_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 291.0
REGS2_k127_7541876_8 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000003678 246.0
REGS2_k127_7541876_9 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000132 231.0
REGS2_k127_7552182_0 protein secretion by the type I secretion system K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 454.0
REGS2_k127_7552182_1 Domain of unknown function (DUF5117) - - - 0.000000001376 64.0
REGS2_k127_7576045_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 361.0
REGS2_k127_7576045_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 310.0
REGS2_k127_7576045_10 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000729 75.0
REGS2_k127_7576045_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000007799 264.0
REGS2_k127_7576045_3 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002548 262.0
REGS2_k127_7576045_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000003683 213.0
REGS2_k127_7576045_5 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000001547 192.0
REGS2_k127_7576045_6 peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000003841 186.0
REGS2_k127_7576045_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000003684 120.0
REGS2_k127_7591346_0 cellulose binding - - - 0.0 1387.0
REGS2_k127_7591346_1 Aldo Keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 368.0
REGS2_k127_7591346_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004619 259.0
REGS2_k127_7591346_3 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000003051 137.0
REGS2_k127_7591346_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000002587 140.0
REGS2_k127_7591346_5 SnoaL-like polyketide cyclase - - - 0.000000000159 68.0
REGS2_k127_7609_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 362.0
REGS2_k127_7609_1 alpha beta alpha domain I - - - 0.0000000000000000000000000000000000000000000000000000000003135 213.0
REGS2_k127_7667211_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003074 261.0
REGS2_k127_7667211_1 WYL domain K13572 - - 0.0000000000000000000000000000000000000000002601 171.0
REGS2_k127_7761177_0 Carboxypeptidase regulatory-like domain - - - 6.835e-205 656.0
REGS2_k127_7761177_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 614.0
REGS2_k127_7761177_2 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000002405 226.0
REGS2_k127_7761177_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000009811 201.0
REGS2_k127_7764465_0 Tricorn protease homolog - - - 3.878e-248 787.0
REGS2_k127_7764465_1 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 336.0
REGS2_k127_7764465_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000003884 139.0
REGS2_k127_7764465_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K21308 - - 0.0000321 57.0
REGS2_k127_7772533_0 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 606.0
REGS2_k127_7772533_1 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000005619 168.0
REGS2_k127_7772533_2 - K05826 - - 0.000000002863 61.0
REGS2_k127_7772533_3 response regulator K02667 - - 0.0000003299 60.0
REGS2_k127_7774649_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 8.226e-212 671.0
REGS2_k127_7774649_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 332.0
REGS2_k127_7774649_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 285.0
REGS2_k127_7774649_3 - - - - 0.000000000000000000000000000008475 126.0
REGS2_k127_7774649_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000001042 120.0
REGS2_k127_7774649_5 Protein tyrosine kinase - - - 0.00000000000000000000001243 107.0
REGS2_k127_7774649_6 OsmC-like protein K04063 - - 0.00000000000000000000006215 103.0
REGS2_k127_7774649_7 membrane - - - 0.00000004048 64.0
REGS2_k127_7774649_8 Domain of unknown function (DUF4203) - - - 0.00003979 53.0
REGS2_k127_7784196_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 342.0
REGS2_k127_7784196_1 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 329.0
REGS2_k127_7784196_2 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000009956 209.0
REGS2_k127_7784196_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000009329 116.0
REGS2_k127_7784403_0 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 548.0
REGS2_k127_7784403_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 451.0
REGS2_k127_7784403_2 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000001062 208.0
REGS2_k127_7784403_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000195 210.0
REGS2_k127_7784403_4 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000002265 201.0
REGS2_k127_7784403_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000001489 108.0
REGS2_k127_7785084_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000001049 139.0
REGS2_k127_7785084_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.000000000000000000000000001419 123.0
REGS2_k127_7785084_2 - - - - 0.00000003045 62.0
REGS2_k127_7792313_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.66e-290 931.0
REGS2_k127_7792313_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.746e-235 738.0
REGS2_k127_7792313_10 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001693 276.0
REGS2_k127_7792313_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005239 279.0
REGS2_k127_7792313_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001409 250.0
REGS2_k127_7792313_13 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
REGS2_k127_7792313_14 spore germination - - - 0.0000000000000000000000000000000000000000000000000000001141 206.0
REGS2_k127_7792313_15 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000000247 205.0
REGS2_k127_7792313_16 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000004722 179.0
REGS2_k127_7792313_17 RNA polymerase sigma factor K02405 - - 0.000000000000000000000000000000000007187 149.0
REGS2_k127_7792313_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000001372 145.0
REGS2_k127_7792313_19 Transcription termination factor nusG - - - 0.0000000000000000000000000000000003091 137.0
REGS2_k127_7792313_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.421e-232 726.0
REGS2_k127_7792313_20 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000001974 134.0
REGS2_k127_7792313_21 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000005783 126.0
REGS2_k127_7792313_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000009056 98.0
REGS2_k127_7792313_23 - - - - 0.0000000001979 62.0
REGS2_k127_7792313_24 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000002397 66.0
REGS2_k127_7792313_25 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000005779 57.0
REGS2_k127_7792313_26 Protein of unknown function (DUF1059) - - - 0.000005131 57.0
REGS2_k127_7792313_27 Stress responsive A/B Barrel Domain - - - 0.00001235 55.0
REGS2_k127_7792313_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 467.0
REGS2_k127_7792313_4 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 440.0
REGS2_k127_7792313_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 349.0
REGS2_k127_7792313_6 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 317.0
REGS2_k127_7792313_7 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 308.0
REGS2_k127_7792313_8 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 302.0
REGS2_k127_7792313_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001182 280.0
REGS2_k127_7799019_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.497e-202 651.0
REGS2_k127_7799019_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 495.0
REGS2_k127_7799019_10 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000001172 128.0
REGS2_k127_7799019_11 - - - - 0.000000000009996 70.0
REGS2_k127_7799019_12 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000114 56.0
REGS2_k127_7799019_14 Class III cytochrome C family - - - 0.0008945 50.0
REGS2_k127_7799019_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 443.0
REGS2_k127_7799019_3 nitrite reductase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 447.0
REGS2_k127_7799019_4 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 364.0
REGS2_k127_7799019_5 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 314.0
REGS2_k127_7799019_6 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 316.0
REGS2_k127_7799019_7 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000001183 230.0
REGS2_k127_7799019_8 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000001391 226.0
REGS2_k127_7799019_9 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000001459 211.0
REGS2_k127_7804930_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 604.0
REGS2_k127_7804930_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 321.0
REGS2_k127_7804930_2 repeat-containing protein - - - 0.0000000000000000000000000000000001347 149.0
REGS2_k127_7809216_0 efflux transmembrane transporter activity - - - 5.493e-216 696.0
REGS2_k127_7809216_1 oxidoreductase activity - - - 0.000000000001065 78.0
REGS2_k127_7825308_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 3.095e-200 648.0
REGS2_k127_7825308_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 542.0
REGS2_k127_7825308_2 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 417.0
REGS2_k127_7825308_3 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 287.0
REGS2_k127_7825308_4 Collagen triple helix repeat (20 copies) - - - 0.0000000000000000000000000000000000000000000747 175.0
REGS2_k127_7825308_5 BMC domain - - - 0.0000000000000000000000000000004543 126.0
REGS2_k127_7825308_6 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016043,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.00000000000000000000000003145 113.0
REGS2_k127_7825308_7 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000004349 95.0
REGS2_k127_7825308_8 helix_turn_helix, mercury resistance - - - 0.000000000000000000007085 99.0
REGS2_k127_7825308_9 acetyltransferase - - - 0.00002109 56.0
REGS2_k127_7830514_0 DEAD DEAH box K03724 - - 0.0 1911.0
REGS2_k127_7830514_1 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 543.0
REGS2_k127_7830514_10 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000002349 94.0
REGS2_k127_7830514_11 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.00000000000000007485 93.0
REGS2_k127_7830514_12 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000007119 74.0
REGS2_k127_7830514_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 532.0
REGS2_k127_7830514_3 Peptidase, M61 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 520.0
REGS2_k127_7830514_4 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 407.0
REGS2_k127_7830514_5 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001462 279.0
REGS2_k127_7830514_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
REGS2_k127_7830514_7 phosphatidylcholine synthase K01004 - 2.7.8.24 0.0000000000000000000000000000000000000000000000000122 188.0
REGS2_k127_7830514_8 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000001082 117.0
REGS2_k127_7830514_9 - - - - 0.00000000000000000000005643 114.0
REGS2_k127_7836294_0 PFAM peptidase - - - 4.563e-206 657.0
REGS2_k127_7836294_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 377.0
REGS2_k127_7836294_10 - - - - 0.000001669 53.0
REGS2_k127_7836294_11 CsbD-like - - - 0.000001696 52.0
REGS2_k127_7836294_2 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 353.0
REGS2_k127_7836294_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004439 226.0
REGS2_k127_7836294_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000006461 221.0
REGS2_k127_7836294_5 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000001692 212.0
REGS2_k127_7836294_6 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000002447 173.0
REGS2_k127_7836294_7 - - - - 0.000000000000000000000000000000003545 131.0
REGS2_k127_7836294_8 - - - - 0.0000000000000000000000003745 110.0
REGS2_k127_7836294_9 - - - - 0.0000000000000000004505 90.0
REGS2_k127_7842818_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 3.271e-196 625.0
REGS2_k127_7842818_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 501.0
REGS2_k127_7842818_10 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000001598 178.0
REGS2_k127_7842818_11 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.0000000000000000000000000000000000000000000001036 173.0
REGS2_k127_7842818_12 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000001784 119.0
REGS2_k127_7842818_13 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000004582 96.0
REGS2_k127_7842818_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 411.0
REGS2_k127_7842818_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 384.0
REGS2_k127_7842818_4 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 351.0
REGS2_k127_7842818_5 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 292.0
REGS2_k127_7842818_6 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004894 266.0
REGS2_k127_7842818_7 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000002368 233.0
REGS2_k127_7842818_8 protoporphyrinogen oxidase activity K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000113 229.0
REGS2_k127_7842818_9 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000003214 194.0
REGS2_k127_7844824_0 oxidoreductase activity - - - 0.000007526 59.0
REGS2_k127_7844824_1 oxidoreductase activity - - - 0.00001194 58.0
REGS2_k127_7851056_0 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 531.0
REGS2_k127_7851056_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 488.0
REGS2_k127_7851056_10 Male sterility protein K15891 - 1.1.1.354 0.0000000000000000000000000000000000000000000000000000000002269 222.0
REGS2_k127_7851056_11 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000001001 188.0
REGS2_k127_7851056_12 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000000000002528 176.0
REGS2_k127_7851056_13 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000138 169.0
REGS2_k127_7851056_14 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000007529 159.0
REGS2_k127_7851056_15 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000006576 141.0
REGS2_k127_7851056_16 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000003576 136.0
REGS2_k127_7851056_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000002688 93.0
REGS2_k127_7851056_18 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000007169 78.0
REGS2_k127_7851056_19 protein methyltransferase activity - - - 0.000000000000005033 86.0
REGS2_k127_7851056_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 488.0
REGS2_k127_7851056_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 476.0
REGS2_k127_7851056_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 331.0
REGS2_k127_7851056_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 305.0
REGS2_k127_7851056_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000163 268.0
REGS2_k127_7851056_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000813 244.0
REGS2_k127_7851056_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000001427 261.0
REGS2_k127_7851056_9 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000001535 246.0
REGS2_k127_7873029_0 Sortilin, neurotensin receptor 3, - - - 0.0 1020.0
REGS2_k127_7873029_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 428.0
REGS2_k127_7873029_2 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000004434 255.0
REGS2_k127_7873029_3 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000004962 206.0
REGS2_k127_7873029_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000007189 195.0
REGS2_k127_7873029_5 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000003989 99.0
REGS2_k127_7890604_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 7.868e-284 887.0
REGS2_k127_7890604_1 Ftsk_gamma K03466 - - 1.709e-194 632.0
REGS2_k127_7890604_10 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000001041 109.0
REGS2_k127_7890604_11 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000009171 85.0
REGS2_k127_7890604_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000009959 67.0
REGS2_k127_7890604_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 574.0
REGS2_k127_7890604_3 peptidase S9 prolyl oligopeptidase active site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 577.0
REGS2_k127_7890604_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 399.0
REGS2_k127_7890604_5 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
REGS2_k127_7890604_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000002133 250.0
REGS2_k127_7890604_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000001623 228.0
REGS2_k127_7890604_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000004554 211.0
REGS2_k127_7890604_9 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000004038 141.0
REGS2_k127_7924543_0 Sortilin, neurotensin receptor 3, - - - 9.089e-304 962.0
REGS2_k127_7924543_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 518.0
REGS2_k127_7924543_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 501.0
REGS2_k127_7924543_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 460.0
REGS2_k127_7924543_4 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 394.0
REGS2_k127_7924543_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000002617 207.0
REGS2_k127_7924543_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000004518 160.0
REGS2_k127_7924543_7 DoxX - - - 0.000000000000000000000000000000000000005008 150.0
REGS2_k127_7924543_8 Transglycosylase associated protein - - - 0.0000000000000000000000000002254 117.0
REGS2_k127_7930474_0 AcrB/AcrD/AcrF family - - - 0.0 1200.0
REGS2_k127_7930474_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 446.0
REGS2_k127_7930474_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009985 244.0
REGS2_k127_7930474_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 0.0000000000000000000000000005828 128.0
REGS2_k127_7930474_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000003166 106.0
REGS2_k127_7930474_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000002495 58.0
REGS2_k127_7930929_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 308.0
REGS2_k127_7930929_1 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000007027 186.0
REGS2_k127_7934970_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 1.052e-253 793.0
REGS2_k127_7934970_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 367.0
REGS2_k127_7934970_2 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000004201 257.0
REGS2_k127_7934970_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000003878 140.0
REGS2_k127_7975322_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 375.0
REGS2_k127_7975322_1 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 285.0
REGS2_k127_7983421_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 379.0
REGS2_k127_7983421_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000001576 247.0
REGS2_k127_7983421_10 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000007369 108.0
REGS2_k127_7983421_12 - - - - 0.0000002565 58.0
REGS2_k127_7983421_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001468 234.0
REGS2_k127_7983421_3 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
REGS2_k127_7983421_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000007943 218.0
REGS2_k127_7983421_5 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000008362 199.0
REGS2_k127_7983421_6 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000001321 168.0
REGS2_k127_7983421_7 oligosaccharyl transferase activity - - - 0.0000000000000000000000000003568 130.0
REGS2_k127_7983421_8 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000005303 121.0
REGS2_k127_7983421_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000001451 119.0
REGS2_k127_7985466_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 357.0
REGS2_k127_7985466_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000006192 196.0
REGS2_k127_7985466_2 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000008396 152.0
REGS2_k127_7985466_3 Peptidase family M48 - - - 0.000000000000000000000000000000000002931 153.0
REGS2_k127_7985466_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000134 72.0
REGS2_k127_7985466_5 Transcriptional regulator, arsR - - - 0.000000002629 63.0
REGS2_k127_7994341_0 efflux transmembrane transporter activity - - - 2.571e-224 721.0
REGS2_k127_7994341_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 455.0
REGS2_k127_7994341_10 -acetyltransferase K06975 - - 0.0000000000000000001078 91.0
REGS2_k127_7994341_12 Belongs to the peptidase S8 family K17734 - - 0.00000001548 62.0
REGS2_k127_7994341_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 273.0
REGS2_k127_7994341_3 polysaccharide deacetylase K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000129 253.0
REGS2_k127_7994341_4 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006832 230.0
REGS2_k127_7994341_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000001656 216.0
REGS2_k127_7994341_6 - - - - 0.000000000000000000000000000000000000000000000000000000005301 211.0
REGS2_k127_7994341_7 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000001597 188.0
REGS2_k127_7994341_8 DoxX - - - 0.00000000000000000000000000000001187 130.0
REGS2_k127_7994341_9 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000001835 129.0
REGS2_k127_8002982_0 Peptidase M14, carboxypeptidase A - - - 1.384e-205 645.0
REGS2_k127_8002982_1 Phospholipid methyltransferase - - - 0.0000000000000004394 89.0
REGS2_k127_8013955_0 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 2.647e-291 918.0
REGS2_k127_8013955_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 5.941e-208 668.0
REGS2_k127_8013955_10 proteins, homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.00000000000000000000000000000008971 132.0
REGS2_k127_8013955_11 DoxX K15977 - - 0.00000000000000000000000002298 114.0
REGS2_k127_8013955_12 Protein of unknown function (DUF1326) - - - 0.00000000000000000000001885 109.0
REGS2_k127_8013955_13 Response regulator receiver domain - - - 0.00000000000001639 78.0
REGS2_k127_8013955_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 503.0
REGS2_k127_8013955_3 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 488.0
REGS2_k127_8013955_4 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003689 279.0
REGS2_k127_8013955_5 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000958 265.0
REGS2_k127_8013955_6 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000003744 243.0
REGS2_k127_8013955_7 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000004934 182.0
REGS2_k127_8013955_8 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000007252 177.0
REGS2_k127_8013955_9 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000005717 156.0
REGS2_k127_8014468_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 535.0
REGS2_k127_8014468_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 511.0
REGS2_k127_8014468_10 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 309.0
REGS2_k127_8014468_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 298.0
REGS2_k127_8014468_12 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000003477 276.0
REGS2_k127_8014468_13 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001375 282.0
REGS2_k127_8014468_14 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000001486 256.0
REGS2_k127_8014468_15 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003676 252.0
REGS2_k127_8014468_16 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000897 251.0
REGS2_k127_8014468_17 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000003921 233.0
REGS2_k127_8014468_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000362 236.0
REGS2_k127_8014468_19 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000004758 177.0
REGS2_k127_8014468_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 481.0
REGS2_k127_8014468_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000004843 173.0
REGS2_k127_8014468_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000001972 154.0
REGS2_k127_8014468_22 thioesterase K07107 - - 0.00000000000000000000000000000000001046 139.0
REGS2_k127_8014468_23 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000002387 142.0
REGS2_k127_8014468_24 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000002741 135.0
REGS2_k127_8014468_25 Chorismate mutase type II K03856,K04092,K04093,K04516,K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000007832 91.0
REGS2_k127_8014468_26 TPR repeat - - - 0.000000000000000007673 97.0
REGS2_k127_8014468_27 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000004468 89.0
REGS2_k127_8014468_28 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000002061 78.0
REGS2_k127_8014468_29 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.00001489 57.0
REGS2_k127_8014468_3 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 473.0
REGS2_k127_8014468_30 Putative zinc-finger - - - 0.0002314 52.0
REGS2_k127_8014468_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 473.0
REGS2_k127_8014468_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 443.0
REGS2_k127_8014468_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 389.0
REGS2_k127_8014468_7 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 373.0
REGS2_k127_8014468_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 346.0
REGS2_k127_8014468_9 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 346.0
REGS2_k127_8017929_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 423.0
REGS2_k127_8017929_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000001935 211.0
REGS2_k127_8025677_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 469.0
REGS2_k127_8025677_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 401.0
REGS2_k127_8025677_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005128 261.0
REGS2_k127_8025677_3 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007153 247.0
REGS2_k127_8025677_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001134 241.0
REGS2_k127_8025677_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
REGS2_k127_8025677_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000003737 94.0
REGS2_k127_8027102_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.319e-243 764.0
REGS2_k127_8027102_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 463.0
REGS2_k127_8027102_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000001893 214.0
REGS2_k127_8027102_11 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000001285 203.0
REGS2_k127_8027102_12 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000005239 211.0
REGS2_k127_8027102_13 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000003717 206.0
REGS2_k127_8027102_14 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000001876 201.0
REGS2_k127_8027102_15 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000009727 160.0
REGS2_k127_8027102_16 Bacteriochlorophyll chlorophyll K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000005384 122.0
REGS2_k127_8027102_17 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000002335 122.0
REGS2_k127_8027102_18 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000002727 82.0
REGS2_k127_8027102_19 phytol kinase activity K15892 - 2.7.1.216 0.00000001079 68.0
REGS2_k127_8027102_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 443.0
REGS2_k127_8027102_20 chaperone-mediated protein folding - - - 0.00008501 55.0
REGS2_k127_8027102_3 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 419.0
REGS2_k127_8027102_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 392.0
REGS2_k127_8027102_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 384.0
REGS2_k127_8027102_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 340.0
REGS2_k127_8027102_7 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001479 280.0
REGS2_k127_8027102_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000204 241.0
REGS2_k127_8027102_9 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000001436 225.0
REGS2_k127_8041652_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
REGS2_k127_8041652_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001986 246.0
REGS2_k127_8041652_2 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000001952 217.0
REGS2_k127_8041652_3 uracil phosphoribosyltransferase K00761 - 2.4.2.9 0.000000000000000000000000004087 111.0
REGS2_k127_8041652_4 Organic solvent ABC transporter substrate-binding protein K02067 - - 0.000000000002741 80.0
REGS2_k127_8041652_5 YtxH-like protein - - - 0.0000001456 57.0
REGS2_k127_8046922_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 3.314e-224 726.0
REGS2_k127_8046922_1 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
REGS2_k127_8046922_2 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000001392 155.0
REGS2_k127_8046922_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000002678 125.0
REGS2_k127_8052690_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002179 271.0
REGS2_k127_8052690_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000002696 165.0
REGS2_k127_8052690_2 TPR repeat - - - 0.00001194 55.0
REGS2_k127_8059966_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003113 280.0
REGS2_k127_8059966_1 Tetratricopeptide repeat - - - 0.000000000000000000000000001263 127.0
REGS2_k127_8063579_0 Zinc carboxypeptidase - - - 5.051e-228 738.0
REGS2_k127_8063579_1 23S rRNA-intervening sequence protein - - - 0.0000008465 58.0
REGS2_k127_8096080_0 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 377.0
REGS2_k127_8096080_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007521 304.0
REGS2_k127_8096080_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003081 245.0
REGS2_k127_8096080_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000005491 235.0
REGS2_k127_8096080_4 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000006201 113.0
REGS2_k127_8096080_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000007465 106.0
REGS2_k127_8109536_0 - - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
REGS2_k127_8109536_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000007892 108.0
REGS2_k127_8109536_2 - - - - 0.00000000000008568 79.0
REGS2_k127_8112253_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 581.0
REGS2_k127_8144971_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000005777 141.0
REGS2_k127_8144971_1 Methionine biosynthesis protein MetW - - - 0.0000000000002669 83.0
REGS2_k127_8150633_0 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 452.0
REGS2_k127_8150633_1 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 406.0
REGS2_k127_8150633_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 340.0
REGS2_k127_8150633_3 Glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 344.0
REGS2_k127_8150633_4 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009122 286.0
REGS2_k127_8150633_5 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000007897 253.0
REGS2_k127_8150633_6 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000002952 246.0
REGS2_k127_8150633_7 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000002802 188.0
REGS2_k127_8150633_8 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000002738 61.0
REGS2_k127_8162480_0 MacB-like periplasmic core domain - - - 1.538e-201 640.0
REGS2_k127_8162484_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 565.0
REGS2_k127_8162484_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 411.0
REGS2_k127_8162484_10 PHP domain protein - - - 0.00000000000000000000000000000001684 144.0
REGS2_k127_8162484_11 BadF BadG BcrA BcrD K00884,K02616 - 2.7.1.59 0.00000000000000000000000007076 113.0
REGS2_k127_8162484_12 GntR family transcriptional regulator K07979 - - 0.000000000000000002097 89.0
REGS2_k127_8162484_2 Permease YjgP YjgQ family protein K07091,K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 404.0
REGS2_k127_8162484_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 366.0
REGS2_k127_8162484_4 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 312.0
REGS2_k127_8162484_5 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 291.0
REGS2_k127_8162484_6 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001731 287.0
REGS2_k127_8162484_7 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000003082 262.0
REGS2_k127_8162484_8 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000008937 222.0
REGS2_k127_8162484_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000043 206.0
REGS2_k127_8166765_0 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 443.0
REGS2_k127_8166765_1 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 359.0
REGS2_k127_8166765_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000002059 135.0
REGS2_k127_8166765_3 methyltransferase activity - - - 0.000000009909 60.0
REGS2_k127_8170920_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 541.0
REGS2_k127_8170920_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 482.0
REGS2_k127_8170920_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003547 140.0
REGS2_k127_8170920_11 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000005008 138.0
REGS2_k127_8170920_12 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000007066 126.0
REGS2_k127_8170920_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000005361 117.0
REGS2_k127_8170920_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000005545 100.0
REGS2_k127_8170920_15 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001591 89.0
REGS2_k127_8170920_16 Belongs to the UPF0109 family K06960 - - 0.000000000000001783 81.0
REGS2_k127_8170920_17 Tetratricopeptide repeats - - - 0.0000000000005904 81.0
REGS2_k127_8170920_18 membrane protein domain - - - 0.0003375 53.0
REGS2_k127_8170920_2 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 358.0
REGS2_k127_8170920_3 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 338.0
REGS2_k127_8170920_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 324.0
REGS2_k127_8170920_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 316.0
REGS2_k127_8170920_6 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001343 284.0
REGS2_k127_8170920_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000009004 267.0
REGS2_k127_8170920_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000009621 196.0
REGS2_k127_8170920_9 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000001708 160.0
REGS2_k127_8213857_0 Dehydrogenase E1 component K11381 - 1.2.4.4 4.34e-276 898.0
REGS2_k127_8213857_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000004938 245.0
REGS2_k127_8213857_10 - - - - 0.0000000000001283 79.0
REGS2_k127_8213857_11 - - - - 0.000000002094 66.0
REGS2_k127_8213857_12 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00001072 57.0
REGS2_k127_8213857_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000002405 216.0
REGS2_k127_8213857_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000001447 221.0
REGS2_k127_8213857_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000001188 154.0
REGS2_k127_8213857_5 - - - - 0.0000000000000000000000000000000000002029 148.0
REGS2_k127_8213857_6 Cupin domain - - - 0.0000000000000000000000000000000000003933 146.0
REGS2_k127_8213857_7 Gas vesicle protein K - - - 0.000000000000000000001193 104.0
REGS2_k127_8213857_8 Gas vesicle - - - 0.000000000000000000002145 104.0
REGS2_k127_8213857_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000001612 84.0
REGS2_k127_8257482_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004359 258.0
REGS2_k127_8257482_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000008016 224.0
REGS2_k127_8257482_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000003795 207.0
REGS2_k127_8257482_3 Heavy-metal resistance - - - 0.00003955 51.0
REGS2_k127_828636_0 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 326.0
REGS2_k127_828636_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 335.0
REGS2_k127_828636_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005801 242.0
REGS2_k127_828636_3 O-acyltransferase activity K00633 - 2.3.1.18 0.0000000000000000000000000000000000000000000000000000000000000001004 235.0
REGS2_k127_828636_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000003656 136.0
REGS2_k127_828636_5 Methyltransferase domain - - - 0.0000000000000000000000000000006686 134.0
REGS2_k127_8316409_0 Ricin-type beta-trefoil - - - 2.456e-244 763.0
REGS2_k127_8316409_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
REGS2_k127_8347681_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
REGS2_k127_8347681_1 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000002198 215.0
REGS2_k127_8347681_2 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000002986 168.0
REGS2_k127_8347681_3 23S rRNA-intervening sequence protein - - - 0.00000002866 59.0
REGS2_k127_8378949_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1193.0
REGS2_k127_8378949_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
REGS2_k127_8378949_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000003566 158.0
REGS2_k127_8378949_3 WD40-like Beta Propeller - - - 0.00000000000000000000000000000008036 132.0
REGS2_k127_8378949_4 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.0000009454 51.0
REGS2_k127_8378949_5 Transcriptional regulator - - - 0.00001668 54.0
REGS2_k127_839660_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.241e-262 837.0
REGS2_k127_839660_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 478.0
REGS2_k127_839660_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 410.0
REGS2_k127_839660_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 320.0
REGS2_k127_839660_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000006588 153.0
REGS2_k127_839660_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000001905 147.0
REGS2_k127_839660_6 Modulates RecA activity K03565 - - 0.00000000008069 73.0
REGS2_k127_839660_7 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000222 48.0
REGS2_k127_8413064_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 476.0
REGS2_k127_8413064_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000001018 235.0
REGS2_k127_8413064_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
REGS2_k127_8413064_3 Phosphoesterase K07098 - - 0.000000000000000000000000000000000000006555 157.0
REGS2_k127_8413064_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0000166,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008144,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0097159,GO:0097367,GO:1901265,GO:1901363 6.3.3.1 0.000000000000000000000000000006359 121.0
REGS2_k127_8413064_5 - - - - 0.0000000000000000000000001421 106.0
REGS2_k127_8413064_6 - - - - 0.0000000000000001138 85.0
REGS2_k127_8423060_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 427.0
REGS2_k127_8423060_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 370.0
REGS2_k127_8423060_2 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000009607 244.0
REGS2_k127_8423060_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000001271 219.0
REGS2_k127_8423060_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000004408 80.0
REGS2_k127_8487809_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 2082.0
REGS2_k127_8487809_1 Protein of unknown function (DUF504) - - - 0.0000000000000000001408 90.0
REGS2_k127_8491194_0 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003625 250.0
REGS2_k127_8491194_1 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000001397 177.0
REGS2_k127_8506241_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1384.0
REGS2_k127_8506241_1 Peptidase family M49 - - - 1.625e-231 729.0
REGS2_k127_8506241_2 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 543.0
REGS2_k127_8506241_3 - - - - 0.000000004764 67.0
REGS2_k127_8507755_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 584.0
REGS2_k127_8507755_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 561.0
REGS2_k127_8507755_10 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 301.0
REGS2_k127_8507755_11 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000651 291.0
REGS2_k127_8507755_12 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000367 293.0
REGS2_k127_8507755_13 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002598 248.0
REGS2_k127_8507755_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000002057 238.0
REGS2_k127_8507755_15 PD-(D/E)XK nuclease superfamily K01144,K03406,K03582,K03658,K07464,K16898,K19465 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5,3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000002425 239.0
REGS2_k127_8507755_16 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000005642 195.0
REGS2_k127_8507755_17 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000003297 183.0
REGS2_k127_8507755_18 Yip1 domain - - - 0.0000000000000000000000000000000000000000008821 167.0
REGS2_k127_8507755_19 COG1651 Protein-disulfide isomerase K21990 - - 0.000000000000000000000000000000000000000004765 164.0
REGS2_k127_8507755_2 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 523.0
REGS2_k127_8507755_20 membrane - - - 0.00000000000000000000001799 103.0
REGS2_k127_8507755_21 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000007356 106.0
REGS2_k127_8507755_22 Thioredoxin domain - - - 0.0000000000000000004763 101.0
REGS2_k127_8507755_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000001246 89.0
REGS2_k127_8507755_24 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000001001 86.0
REGS2_k127_8507755_25 Transcriptional regulator K03892,K21903 - - 0.00000000000002697 79.0
REGS2_k127_8507755_26 - - - - 0.00000000005182 70.0
REGS2_k127_8507755_27 protein targeting K03070,K07039 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000008623 56.0
REGS2_k127_8507755_28 Asparaginase - - - 0.000008339 49.0
REGS2_k127_8507755_29 O-methyltransferase - - - 0.0004358 51.0
REGS2_k127_8507755_3 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
REGS2_k127_8507755_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 403.0
REGS2_k127_8507755_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 375.0
REGS2_k127_8507755_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 369.0
REGS2_k127_8507755_7 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 328.0
REGS2_k127_8507755_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 309.0
REGS2_k127_8507755_9 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
REGS2_k127_8577081_0 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 525.0
REGS2_k127_8577081_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 364.0
REGS2_k127_8577081_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 289.0
REGS2_k127_8577081_3 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002381 244.0
REGS2_k127_8577081_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000004152 240.0
REGS2_k127_8577081_5 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000001686 190.0
REGS2_k127_8577081_6 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000001226 125.0
REGS2_k127_8577081_7 - - - - 0.000000000000000000000000009617 115.0
REGS2_k127_8577081_9 Peptidase dimerisation domain - - - 0.00000189 50.0
REGS2_k127_864354_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 397.0
REGS2_k127_864354_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 394.0
REGS2_k127_864354_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000001348 221.0
REGS2_k127_864354_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000001187 145.0
REGS2_k127_864354_4 Iodothyronine deiodinase - - - 0.0000000000000000000000000005094 115.0
REGS2_k127_864354_5 - - - - 0.00000000000000008932 83.0
REGS2_k127_864354_6 Carboxylesterase family K03929 - - 0.0000000000000009201 78.0
REGS2_k127_864354_7 Virulence factor BrkB K07058 - - 0.0006046 45.0
REGS2_k127_86568_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1126.0
REGS2_k127_86568_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
REGS2_k127_86568_2 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000001802 156.0
REGS2_k127_86568_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000002482 78.0
REGS2_k127_866677_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 581.0
REGS2_k127_866677_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 543.0
REGS2_k127_866677_2 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 498.0
REGS2_k127_866677_3 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 342.0
REGS2_k127_866677_4 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000004313 227.0
REGS2_k127_866677_5 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
REGS2_k127_866677_6 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000009398 193.0
REGS2_k127_866677_7 - - - - 0.00000000000000000000000000004406 120.0
REGS2_k127_878844_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1184.0
REGS2_k127_878844_1 cellulose binding - - - 1.535e-229 727.0
REGS2_k127_878844_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
REGS2_k127_884095_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 526.0
REGS2_k127_884095_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 515.0
REGS2_k127_884095_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000005353 199.0
REGS2_k127_884095_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000001048 188.0
REGS2_k127_884095_12 O-Antigen ligase K18814 - - 0.00000000000000000000000000000000000000000000002552 185.0
REGS2_k127_884095_13 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001583 167.0
REGS2_k127_884095_14 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000001031 155.0
REGS2_k127_884095_15 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000001664 148.0
REGS2_k127_884095_16 Cold shock K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000004271 117.0
REGS2_k127_884095_17 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000001001 105.0
REGS2_k127_884095_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000001047 110.0
REGS2_k127_884095_19 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000001104 99.0
REGS2_k127_884095_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 475.0
REGS2_k127_884095_20 Trm112p-like protein K09791 - - 0.000000000000000003785 89.0
REGS2_k127_884095_21 - - - - 0.0000000000000004799 85.0
REGS2_k127_884095_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 407.0
REGS2_k127_884095_4 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 385.0
REGS2_k127_884095_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000197 273.0
REGS2_k127_884095_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000001097 245.0
REGS2_k127_884095_7 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001248 228.0
REGS2_k127_884095_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000173 199.0
REGS2_k127_884095_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000002275 192.0
REGS2_k127_887666_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 416.0
REGS2_k127_887666_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 429.0
REGS2_k127_887666_10 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000003876 132.0
REGS2_k127_887666_13 metallopeptidase activity - - - 0.00000005386 67.0
REGS2_k127_887666_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 370.0
REGS2_k127_887666_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004652 289.0
REGS2_k127_887666_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000538 206.0
REGS2_k127_887666_5 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000005676 190.0
REGS2_k127_887666_6 PFAM lipopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000002799 188.0
REGS2_k127_887666_7 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000008882 173.0
REGS2_k127_887666_8 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000002902 152.0
REGS2_k127_887666_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000001374 138.0
REGS2_k127_893944_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.343e-315 974.0
REGS2_k127_913125_0 oxidoreductase activity - - - 0.0000000000004773 81.0
REGS2_k127_916344_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 493.0
REGS2_k127_916344_1 Chase2 domain K01768,K07814 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 432.0
REGS2_k127_916344_2 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 297.0
REGS2_k127_916344_3 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000002182 210.0
REGS2_k127_916344_4 OmpA family - - - 0.0000000000000000000000000000000004892 138.0
REGS2_k127_916344_5 FecR protein - - - 0.000000000000000000000000000001977 128.0
REGS2_k127_916344_6 enterobactin catabolic process K07214 - - 0.00003298 56.0
REGS2_k127_923722_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1046.0
REGS2_k127_923722_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 455.0
REGS2_k127_923722_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 411.0
REGS2_k127_923722_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001373 246.0
REGS2_k127_923722_4 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000007419 215.0
REGS2_k127_923722_5 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000127 159.0
REGS2_k127_923722_6 Domain of unknown function (DUF4437) - - - 0.0000000000000000000000000000000001668 142.0
REGS2_k127_924145_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1557.0
REGS2_k127_924145_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.206e-220 707.0
REGS2_k127_924145_10 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008893 261.0
REGS2_k127_924145_11 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
REGS2_k127_924145_12 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008278 266.0
REGS2_k127_924145_13 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000002559 201.0
REGS2_k127_924145_14 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000000000000000003984 186.0
REGS2_k127_924145_15 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000001065 180.0
REGS2_k127_924145_17 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000006748 140.0
REGS2_k127_924145_18 Biogenesis protein - - - 0.00000000000000000000000000000005063 134.0
REGS2_k127_924145_19 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000002805 132.0
REGS2_k127_924145_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 414.0
REGS2_k127_924145_20 nickel cation binding K04651 - - 0.0000000000000000000008677 104.0
REGS2_k127_924145_21 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000134 86.0
REGS2_k127_924145_22 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000383 85.0
REGS2_k127_924145_23 radical SAM domain protein - - - 0.00000000000001329 86.0
REGS2_k127_924145_24 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000002108 80.0
REGS2_k127_924145_25 - - - - 0.000002166 60.0
REGS2_k127_924145_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 414.0
REGS2_k127_924145_4 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 399.0
REGS2_k127_924145_5 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 391.0
REGS2_k127_924145_6 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 316.0
REGS2_k127_924145_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 306.0
REGS2_k127_924145_8 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 313.0
REGS2_k127_924145_9 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001325 293.0
REGS2_k127_927487_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 388.0
REGS2_k127_927487_1 Enoyl-CoA hydratase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 331.0
REGS2_k127_927487_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 302.0
REGS2_k127_927487_3 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 301.0
REGS2_k127_927487_4 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
REGS2_k127_927487_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000007876 213.0
REGS2_k127_932236_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 441.0
REGS2_k127_932236_1 Tricorn protease homolog - - - 0.000000000000000000008755 106.0
REGS2_k127_932236_2 Peptidase family M3 K01284 - 3.4.15.5 0.000000008684 56.0
REGS2_k127_945044_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 513.0
REGS2_k127_945044_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 494.0
REGS2_k127_945044_2 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 420.0
REGS2_k127_945044_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 412.0
REGS2_k127_945044_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000006956 232.0
REGS2_k127_945044_5 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000001213 231.0
REGS2_k127_945044_6 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
REGS2_k127_945044_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000002333 135.0
REGS2_k127_945044_8 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000457 112.0
REGS2_k127_953825_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 495.0
REGS2_k127_953825_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 411.0
REGS2_k127_953825_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 330.0
REGS2_k127_953825_3 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000002691 210.0
REGS2_k127_953825_4 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000001226 115.0
REGS2_k127_963270_0 mismatched DNA binding K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 400.0
REGS2_k127_963270_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000004598 160.0
REGS2_k127_967815_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 446.0
REGS2_k127_967815_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 386.0
REGS2_k127_967815_10 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000006252 91.0
REGS2_k127_967815_11 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000005295 81.0
REGS2_k127_967815_12 amino acid transport K02030 - - 0.00000000002144 77.0
REGS2_k127_967815_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 312.0
REGS2_k127_967815_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001949 262.0
REGS2_k127_967815_4 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000001697 226.0
REGS2_k127_967815_5 - - - - 0.0000000000000000000000000000000000000000000000000002022 196.0
REGS2_k127_967815_6 HWE histidine kinase - - - 0.0000000000000000000000000000000000000008202 167.0
REGS2_k127_967815_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K16881 GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000001301 149.0
REGS2_k127_967815_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000002886 143.0
REGS2_k127_967815_9 CYTH K05873 - 4.6.1.1 0.000000000000000000000002193 109.0
REGS2_k127_967912_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 7.409e-283 893.0
REGS2_k127_967912_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 1.538e-236 745.0
REGS2_k127_967912_2 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 500.0
REGS2_k127_967912_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 466.0
REGS2_k127_967912_4 Cytochrome c K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 348.0
REGS2_k127_967912_5 oxidase subunit K08738 - - 0.000000000000000000000000000000000000000128 165.0
REGS2_k127_967912_6 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000007989 145.0
REGS2_k127_967912_7 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000000000006629 124.0
REGS2_k127_967912_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000003452 63.0
REGS2_k127_976675_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 334.0
REGS2_k127_976675_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
REGS2_k127_976675_2 Conserved hypothetical protein 95 - - - 0.0000879 45.0
REGS2_k127_977793_0 membrane K07027,K14205 - 2.3.2.3 7.188e-253 804.0
REGS2_k127_977793_1 FMN reductase (NADPH) activity - - - 0.00000000000000000000000000000000000000000000000000000008773 204.0
REGS2_k127_977793_2 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000489 181.0
REGS2_k127_977793_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000001234 145.0
REGS2_k127_977793_5 of the alpha beta superfamily - - - 0.00000008465 64.0
REGS2_k127_981388_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
REGS2_k127_981388_1 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000241 231.0
REGS2_k127_981388_2 - - - - 0.000000001061 64.0
REGS2_k127_981388_3 Protein of unknown function (DUF2934) - - - 0.00005007 50.0
REGS2_k127_987219_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
REGS2_k127_987219_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 327.0
REGS2_k127_987219_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000002345 203.0
REGS2_k127_987219_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000001497 152.0
REGS2_k127_993285_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.189e-194 629.0
REGS2_k127_993285_1 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 548.0
REGS2_k127_993285_10 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
REGS2_k127_993285_11 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000007268 252.0
REGS2_k127_993285_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000007344 209.0
REGS2_k127_993285_13 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000001056 203.0
REGS2_k127_993285_14 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000002531 181.0
REGS2_k127_993285_15 Survival protein SurE K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000003597 188.0
REGS2_k127_993285_16 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000309 151.0
REGS2_k127_993285_17 peptidase - - - 0.00000000000000000000000000000005274 140.0
REGS2_k127_993285_18 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000005507 109.0
REGS2_k127_993285_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000001111 97.0
REGS2_k127_993285_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 517.0
REGS2_k127_993285_20 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000002551 85.0
REGS2_k127_993285_21 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.0000000000000007431 88.0
REGS2_k127_993285_22 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000005019 72.0
REGS2_k127_993285_23 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000123 71.0
REGS2_k127_993285_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000001192 70.0
REGS2_k127_993285_25 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0008150,GO:0040007 2.7.4.16 0.00000000007262 69.0
REGS2_k127_993285_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 464.0
REGS2_k127_993285_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 449.0
REGS2_k127_993285_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
REGS2_k127_993285_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 385.0
REGS2_k127_993285_7 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 312.0
REGS2_k127_993285_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 263.0
REGS2_k127_993285_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008054 258.0