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Overview

ID MAG03354
Name REGS3_bin.22
Sample SMP0081
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family JACQAP01
Genus JACQAP01
Species
Assembly information
Completeness (%) 96.56
Contamination (%) 1.37
GC content (%) 62.0
N50 (bp) 10,556
Genome size (bp) 3,593,885

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3523

Gene name Description KEGG GOs EC E-value Score Sequence
REGS3_k127_1004837_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 459.0
REGS3_k127_1004837_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 401.0
REGS3_k127_1004837_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 333.0
REGS3_k127_1004837_3 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001127 267.0
REGS3_k127_1004837_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000002622 177.0
REGS3_k127_1004837_5 cheY-homologous receiver domain - - - 0.0000000000000000004816 92.0
REGS3_k127_1004837_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000002356 83.0
REGS3_k127_1011937_0 PFAM Glycosyl transferase, family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 409.0
REGS3_k127_1011937_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 293.0
REGS3_k127_1011937_2 Flavin reductase like domain - - - 0.0000000000004449 68.0
REGS3_k127_1011937_3 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.00000000001185 64.0
REGS3_k127_1011937_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000003492 72.0
REGS3_k127_1012559_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1484.0
REGS3_k127_1012559_1 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 557.0
REGS3_k127_1012559_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 417.0
REGS3_k127_1012559_3 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 306.0
REGS3_k127_1012559_4 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000001614 183.0
REGS3_k127_1012559_5 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000002972 102.0
REGS3_k127_1012559_6 T3SS negative regulator,GrlR - - - 0.0000000002458 66.0
REGS3_k127_1029521_0 type II secretion system protein E K02454,K02652 - - 4.267e-234 752.0
REGS3_k127_1029521_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
REGS3_k127_1029521_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003364 220.0
REGS3_k127_1029521_3 MltA-interacting protein MipA - - - 0.0000000000004349 79.0
REGS3_k127_1033347_0 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 522.0
REGS3_k127_1033347_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 355.0
REGS3_k127_1033347_2 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001252 278.0
REGS3_k127_1041231_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 475.0
REGS3_k127_1041231_1 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 374.0
REGS3_k127_1041231_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004611 274.0
REGS3_k127_1041231_3 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001848 251.0
REGS3_k127_1041231_4 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001639 240.0
REGS3_k127_1041231_5 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.00000000000000000000000000000000000005643 148.0
REGS3_k127_1041231_6 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000197 106.0
REGS3_k127_1041231_7 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000001059 106.0
REGS3_k127_1041231_8 OmpA-like transmembrane domain K16079 - - 0.000121 52.0
REGS3_k127_1049117_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.133e-237 740.0
REGS3_k127_1049117_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002919 293.0
REGS3_k127_1056769_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1229.0
REGS3_k127_1056769_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 597.0
REGS3_k127_1056769_10 - - - - 0.000000002751 68.0
REGS3_k127_1056769_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 498.0
REGS3_k127_1056769_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 477.0
REGS3_k127_1056769_4 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 443.0
REGS3_k127_1056769_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 317.0
REGS3_k127_1056769_6 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
REGS3_k127_1056769_7 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000002895 228.0
REGS3_k127_1056769_8 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000008123 188.0
REGS3_k127_1056769_9 Permease MlaE K02066 - - 0.0000000000000000000004987 108.0
REGS3_k127_1057118_0 Extracellular solute-binding protein K02027 - - 1.953e-218 683.0
REGS3_k127_1057118_1 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 530.0
REGS3_k127_1057118_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000007783 52.0
REGS3_k127_1057118_2 Binding-protein-dependent transport system inner membrane component K02026,K10229 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 498.0
REGS3_k127_1057118_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 481.0
REGS3_k127_1057118_4 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 443.0
REGS3_k127_1057118_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007169 252.0
REGS3_k127_1057118_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000003846 168.0
REGS3_k127_1057118_7 negative regulation of translational initiation - - - 0.0000000000000000000000000000000000000006438 154.0
REGS3_k127_1057118_8 OmpA-like transmembrane domain - - - 0.00000000000000002976 90.0
REGS3_k127_1068279_0 B12 binding domain - - - 1.976e-230 725.0
REGS3_k127_1068279_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
REGS3_k127_1068279_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 327.0
REGS3_k127_1068279_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 323.0
REGS3_k127_1068279_4 YCII-related domain - - - 0.0000000000000000000000000000000000000000001666 162.0
REGS3_k127_1083009_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.305e-277 863.0
REGS3_k127_1083009_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 307.0
REGS3_k127_1083009_2 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 304.0
REGS3_k127_1090375_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 6.777e-301 929.0
REGS3_k127_1090375_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 601.0
REGS3_k127_1090375_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000006344 98.0
REGS3_k127_1110394_0 peptidase U62, modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 598.0
REGS3_k127_1110394_1 Protein of unknown function (DUF615) K09889 - - 0.00000000000000000000000000000000000000000005643 166.0
REGS3_k127_1110394_2 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.00000000000004698 74.0
REGS3_k127_1111156_0 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 1.853e-215 677.0
REGS3_k127_1111156_1 HAD-hyrolase-like K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000607 164.0
REGS3_k127_1128951_0 Tetratricopeptide repeat - - - 9.832e-291 906.0
REGS3_k127_1128951_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 265.0
REGS3_k127_1128951_2 - - - - 0.000000000000000000000000000000266 124.0
REGS3_k127_1128951_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000008585 54.0
REGS3_k127_1135562_0 PFAM AMP-dependent synthetase and ligase - - - 4.234e-232 728.0
REGS3_k127_1135562_1 twitching motility protein K02670 - - 1.601e-208 651.0
REGS3_k127_1135562_10 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 379.0
REGS3_k127_1135562_11 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 315.0
REGS3_k127_1135562_12 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 319.0
REGS3_k127_1135562_13 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 302.0
REGS3_k127_1135562_14 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000011 287.0
REGS3_k127_1135562_15 Benzoate membrane transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007714 262.0
REGS3_k127_1135562_16 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001534 243.0
REGS3_k127_1135562_17 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000009922 232.0
REGS3_k127_1135562_18 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000000000000001112 203.0
REGS3_k127_1135562_19 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000002042 200.0
REGS3_k127_1135562_2 twitching motility protein K02669 - - 1.09e-197 618.0
REGS3_k127_1135562_20 Ferredoxin - - - 0.000000000000000000000000000000000000000000000005338 177.0
REGS3_k127_1135562_21 HIRAN domain - - - 0.000000000000000000000000000000000000000232 158.0
REGS3_k127_1135562_22 MazG-like family - - - 0.00000000000000000000000000000000000006367 146.0
REGS3_k127_1135562_23 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000009323 139.0
REGS3_k127_1135562_24 Belongs to the UPF0235 family K09131 - - 0.000000000000000000002146 97.0
REGS3_k127_1135562_3 PFAM major facilitator superfamily MFS_1 K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 579.0
REGS3_k127_1135562_4 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 544.0
REGS3_k127_1135562_5 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 508.0
REGS3_k127_1135562_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 502.0
REGS3_k127_1135562_7 THUMP K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 488.0
REGS3_k127_1135562_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 463.0
REGS3_k127_1135562_9 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 435.0
REGS3_k127_1146633_0 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 9.722e-255 787.0
REGS3_k127_11530_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.97e-218 688.0
REGS3_k127_11530_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 603.0
REGS3_k127_11530_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 582.0
REGS3_k127_1181006_0 Transmembrane secretion effector - - - 2.952e-237 749.0
REGS3_k127_1181006_1 PFAM General substrate transporter - - - 1.365e-217 692.0
REGS3_k127_1181006_10 nuclease - - - 0.00000000000000000000000000000000000000000000000000000797 197.0
REGS3_k127_1181006_11 alginic acid biosynthetic process K20276 - - 0.00000000000000000000000000000000000000000000000002972 190.0
REGS3_k127_1181006_12 membrane-anchored protein conserved in bacteria - - - 0.0000000000000000000000005137 107.0
REGS3_k127_1181006_13 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0003371 47.0
REGS3_k127_1181006_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 422.0
REGS3_k127_1181006_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 416.0
REGS3_k127_1181006_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 416.0
REGS3_k127_1181006_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 392.0
REGS3_k127_1181006_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 303.0
REGS3_k127_1181006_7 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000004329 251.0
REGS3_k127_1181006_8 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000003888 226.0
REGS3_k127_1181006_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000001392 206.0
REGS3_k127_1203088_0 Amidohydrolase family - - - 2.408e-211 671.0
REGS3_k127_1203088_1 PFAM transcription elongation factor GreA GreB - - - 0.0000000000000000000000000000000000000000000005019 174.0
REGS3_k127_1203088_2 CoA-transferase family III - - - 0.000000000000000000000002166 104.0
REGS3_k127_1203088_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000005542 105.0
REGS3_k127_1203088_4 Sugar kinases ribokinase family K00874 - 2.7.1.45 0.00000000000000000003047 91.0
REGS3_k127_1203961_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 302.0
REGS3_k127_1203961_1 Metallo-beta-lactamase superfamily - - - 0.0001088 51.0
REGS3_k127_1204063_0 Belongs to the glutamate synthase family K22083 - 2.1.1.21 1.838e-254 800.0
REGS3_k127_1204063_1 Ammonium Transporter K03320 - - 9.131e-218 687.0
REGS3_k127_1204063_2 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 336.0
REGS3_k127_1204063_3 GXGXG motif K22082 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 321.0
REGS3_k127_1204063_4 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 302.0
REGS3_k127_1204063_5 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000001887 195.0
REGS3_k127_1204063_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000135 167.0
REGS3_k127_1215198_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 581.0
REGS3_k127_1215198_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000001187 145.0
REGS3_k127_1215198_2 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000009226 143.0
REGS3_k127_1225405_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.778e-243 773.0
REGS3_k127_1225405_1 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 649.0
REGS3_k127_1225405_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 318.0
REGS3_k127_1225405_11 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 327.0
REGS3_k127_1225405_12 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000000000004604 211.0
REGS3_k127_1225405_13 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000001684 205.0
REGS3_k127_1225405_14 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000003272 203.0
REGS3_k127_1225405_15 peptidase S16 K07157 - - 0.00000000000000000000000000000000000000000000000001282 185.0
REGS3_k127_1225405_16 protein conserved in bacteria K11719 - - 0.0000000000000000000000000000000000000000000000004526 189.0
REGS3_k127_1225405_17 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000003699 148.0
REGS3_k127_1225405_18 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000001881 146.0
REGS3_k127_1225405_19 ThiS family K03154 - - 0.0000000000000000002196 91.0
REGS3_k127_1225405_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 587.0
REGS3_k127_1225405_20 - - - - 0.00005135 49.0
REGS3_k127_1225405_3 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 490.0
REGS3_k127_1225405_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 442.0
REGS3_k127_1225405_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 433.0
REGS3_k127_1225405_6 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 398.0
REGS3_k127_1225405_7 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 400.0
REGS3_k127_1225405_8 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 387.0
REGS3_k127_1225405_9 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 370.0
REGS3_k127_1277528_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 2.082e-315 985.0
REGS3_k127_1277528_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 487.0
REGS3_k127_1277528_2 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000001303 118.0
REGS3_k127_1286436_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 2.061e-212 668.0
REGS3_k127_1286436_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 405.0
REGS3_k127_1286436_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000001864 234.0
REGS3_k127_1286436_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000002103 181.0
REGS3_k127_1286436_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000004788 156.0
REGS3_k127_1286436_5 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000000000611 152.0
REGS3_k127_1286436_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000009756 84.0
REGS3_k127_1286436_7 - - - - 0.0000000000000007121 82.0
REGS3_k127_1286436_8 - - - - 0.00000000442 66.0
REGS3_k127_1316360_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 369.0
REGS3_k127_1316360_1 luciferase - - - 0.00000000000000000000000000000000000001071 149.0
REGS3_k127_1316360_2 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000202 118.0
REGS3_k127_1326512_0 Ammonium Transporter Family K03320,K06580 - - 4.053e-215 672.0
REGS3_k127_1326512_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 569.0
REGS3_k127_1326512_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 555.0
REGS3_k127_1326512_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 459.0
REGS3_k127_1326512_4 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 347.0
REGS3_k127_1326512_5 type II secretion system protein E K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
REGS3_k127_1326512_6 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001823 280.0
REGS3_k127_134701_0 Amidase K01426 - 3.5.1.4 3.65e-231 727.0
REGS3_k127_134701_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 328.0
REGS3_k127_134701_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 308.0
REGS3_k127_134701_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 301.0
REGS3_k127_134701_4 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 293.0
REGS3_k127_134701_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008171 264.0
REGS3_k127_134701_6 DoxX K15977 - - 0.00000000000000000000000000000000000000000000003024 173.0
REGS3_k127_1397630_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 1.731e-195 615.0
REGS3_k127_1397630_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 583.0
REGS3_k127_1397630_2 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000001834 173.0
REGS3_k127_1397630_3 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000000001793 136.0
REGS3_k127_142919_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 9.489e-202 638.0
REGS3_k127_142919_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.022e-198 629.0
REGS3_k127_142919_10 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 374.0
REGS3_k127_142919_11 Sec-independent protein translocase protein (TatC) K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 359.0
REGS3_k127_142919_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 350.0
REGS3_k127_142919_13 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 331.0
REGS3_k127_142919_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 320.0
REGS3_k127_142919_15 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 304.0
REGS3_k127_142919_16 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001552 247.0
REGS3_k127_142919_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
REGS3_k127_142919_18 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
REGS3_k127_142919_19 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000001595 208.0
REGS3_k127_142919_2 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 545.0
REGS3_k127_142919_20 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000004523 194.0
REGS3_k127_142919_21 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000003564 180.0
REGS3_k127_142919_22 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000009583 173.0
REGS3_k127_142919_23 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000004881 166.0
REGS3_k127_142919_24 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000001134 158.0
REGS3_k127_142919_25 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000001524 132.0
REGS3_k127_142919_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000001955 107.0
REGS3_k127_142919_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000315 111.0
REGS3_k127_142919_28 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000003741 105.0
REGS3_k127_142919_29 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.00000000000000002001 85.0
REGS3_k127_142919_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 527.0
REGS3_k127_142919_30 transporter antisigma-factor antagonist STAS K07122 - - 0.0000000000000002858 83.0
REGS3_k127_142919_31 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00007398 52.0
REGS3_k127_142919_4 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 444.0
REGS3_k127_142919_5 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 423.0
REGS3_k127_142919_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 413.0
REGS3_k127_142919_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 401.0
REGS3_k127_142919_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 399.0
REGS3_k127_142919_9 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
REGS3_k127_1445303_0 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 308.0
REGS3_k127_1445303_1 phosphorelay signal transduction system - - - 0.000000000006713 75.0
REGS3_k127_1445303_2 His Kinase A (phosphoacceptor) domain - - - 0.000000004176 60.0
REGS3_k127_145326_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.759e-241 754.0
REGS3_k127_145326_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 1.653e-199 633.0
REGS3_k127_145326_2 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 578.0
REGS3_k127_145326_3 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 557.0
REGS3_k127_145326_4 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 384.0
REGS3_k127_145326_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 366.0
REGS3_k127_145326_6 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
REGS3_k127_145326_7 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000001799 205.0
REGS3_k127_145326_8 GXGXG motif - - - 0.000000000000000000000000000000000000000003699 159.0
REGS3_k127_145326_9 Protein conserved in bacteria - - - 0.00000001892 62.0
REGS3_k127_1457768_0 Site-specific recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 475.0
REGS3_k127_1457768_1 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000008383 236.0
REGS3_k127_1457768_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000002777 179.0
REGS3_k127_1467592_0 Glucose / Sorbosone dehydrogenase - - - 3.033e-229 719.0
REGS3_k127_1467592_1 COG1032 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 581.0
REGS3_k127_1467592_10 uridine kinase - - - 0.0000000000000000000000000002755 124.0
REGS3_k127_1467592_11 Domain of unknown function (DUF4124) - - - 0.0000000000000000002374 94.0
REGS3_k127_1467592_12 - - - - 0.0000000004347 63.0
REGS3_k127_1467592_2 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 525.0
REGS3_k127_1467592_3 Helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 459.0
REGS3_k127_1467592_4 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 411.0
REGS3_k127_1467592_5 PFAM O-methyltransferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 314.0
REGS3_k127_1467592_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 301.0
REGS3_k127_1467592_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006516 278.0
REGS3_k127_1467592_8 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009794 275.0
REGS3_k127_1467592_9 - - - - 0.00000000000000000000000000000000000000001132 168.0
REGS3_k127_1481996_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 3.534e-246 773.0
REGS3_k127_1481996_1 Catalyzes the isomerization of sulfoquinovose (SQ) to 6- deoxy-6-sulfo-D-fructose (SF) K18479 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016861,GO:0019637,GO:0034308,GO:0042180,GO:0042802,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0050089,GO:0061593,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 5.3.1.31 3.163e-197 620.0
REGS3_k127_1481996_2 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 355.0
REGS3_k127_1481996_3 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 291.0
REGS3_k127_1481996_4 Glycosyltransferase like family - - - 0.00000000000000000000000000000000000000000000000000000000001154 215.0
REGS3_k127_1481996_5 thioesterase K01075 - 3.1.2.23 0.000000000000000000000000002436 122.0
REGS3_k127_1481996_6 - - - - 0.000000000000000000000001041 109.0
REGS3_k127_1494391_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 5.976e-293 921.0
REGS3_k127_1494391_1 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000007024 251.0
REGS3_k127_1494391_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000001782 219.0
REGS3_k127_1494391_3 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000000005796 190.0
REGS3_k127_1494391_4 transporter component - - - 0.000000000000000000000000000000000000000000003438 171.0
REGS3_k127_1494391_5 Peptidase M61 - - - 0.000000000000000000002595 95.0
REGS3_k127_1494391_6 Glycoside Hydrolase - - - 0.000000000002371 76.0
REGS3_k127_1516229_0 ABC transporter substrate-binding protein K01999 - - 7.319e-206 647.0
REGS3_k127_1516229_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 454.0
REGS3_k127_1516229_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 390.0
REGS3_k127_1516229_3 maleylacetate reductase K00217 - 1.3.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 372.0
REGS3_k127_1516229_4 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 350.0
REGS3_k127_1516229_5 Abc transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 327.0
REGS3_k127_1516229_6 Catechol dioxygenase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 258.0
REGS3_k127_166822_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.79e-284 881.0
REGS3_k127_166822_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 484.0
REGS3_k127_166822_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000001671 204.0
REGS3_k127_166822_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.000186 48.0
REGS3_k127_1721008_0 Amidohydrolase family - - - 1.38e-275 860.0
REGS3_k127_1721008_1 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 458.0
REGS3_k127_1721008_2 PFAM GHMP kinases C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 343.0
REGS3_k127_1721008_3 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 335.0
REGS3_k127_1721008_4 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.000000000000000000000000000000000000000000000000000000000000001103 228.0
REGS3_k127_1721008_5 GXGXG motif K00202 - 1.2.7.12 0.000000000000000000000000000000001477 138.0
REGS3_k127_1727899_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 522.0
REGS3_k127_1727899_1 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 445.0
REGS3_k127_1727899_2 HlyD family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 318.0
REGS3_k127_1727899_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000003572 130.0
REGS3_k127_1727899_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000003872 106.0
REGS3_k127_1728774_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1042.0
REGS3_k127_1728774_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 456.0
REGS3_k127_1728774_10 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000001108 228.0
REGS3_k127_1728774_11 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000001287 110.0
REGS3_k127_1728774_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000002551 103.0
REGS3_k127_1728774_13 PFAM Cytochrome c, class I - - - 0.000000000000000000001798 100.0
REGS3_k127_1728774_14 Putative Actinobacterial Holin-X, holin superfamily III - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001188 67.0
REGS3_k127_1728774_15 cytochrome K17230 - - 0.0006697 45.0
REGS3_k127_1728774_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 437.0
REGS3_k127_1728774_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 372.0
REGS3_k127_1728774_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 352.0
REGS3_k127_1728774_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 330.0
REGS3_k127_1728774_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005464 276.0
REGS3_k127_1728774_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
REGS3_k127_1728774_8 membrane protein, TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
REGS3_k127_1728774_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000104 257.0
REGS3_k127_1731151_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.908e-237 766.0
REGS3_k127_1731151_1 Secretin and TonB N terminus short domain K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 621.0
REGS3_k127_1731151_10 phospholipase C - - - 0.0000000002249 63.0
REGS3_k127_1731151_2 Bacterial protein of unknown function (DUF839) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 605.0
REGS3_k127_1731151_3 PFAM type II secretion system K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 496.0
REGS3_k127_1731151_4 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000007672 229.0
REGS3_k127_1731151_5 - - - - 0.000000000000000000000000000000000001895 145.0
REGS3_k127_1731151_6 Pilus assembly protein, PilO - - - 0.0000000000000000000000000001797 123.0
REGS3_k127_1731151_7 - - - - 0.000000000000000000000000000244 125.0
REGS3_k127_1731151_8 - - - - 0.000000000000000000000008059 110.0
REGS3_k127_1731151_9 - - - - 0.00000000000000000000003646 106.0
REGS3_k127_1743337_0 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000002075 202.0
REGS3_k127_1743337_1 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000001506 156.0
REGS3_k127_1743337_2 Invasion gene expression up-regulator, SirB - - - 0.000000000002419 68.0
REGS3_k127_1745482_0 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 501.0
REGS3_k127_1745482_1 CsbD-like - - - 0.00000000000000000001882 92.0
REGS3_k127_1753937_0 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 4.305e-219 689.0
REGS3_k127_1753937_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 332.0
REGS3_k127_175899_0 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 524.0
REGS3_k127_175899_1 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 301.0
REGS3_k127_175899_2 PFAM response regulator receiver K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 291.0
REGS3_k127_175899_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000003962 203.0
REGS3_k127_1762598_0 D-aminoacylase domain protein K06015 - 3.5.1.81 2.251e-217 683.0
REGS3_k127_1762598_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 531.0
REGS3_k127_1762598_10 Cytochrome c - - - 0.000000000000000000002604 98.0
REGS3_k127_1762598_11 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.000000000001965 76.0
REGS3_k127_1762598_12 - - - - 0.00000004274 61.0
REGS3_k127_1762598_2 COG4618 ABC-type protease lipase transport system, ATPase and permease components K16299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 516.0
REGS3_k127_1762598_3 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 456.0
REGS3_k127_1762598_4 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 410.0
REGS3_k127_1762598_5 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022,K12537 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 355.0
REGS3_k127_1762598_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 335.0
REGS3_k127_1762598_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001177 285.0
REGS3_k127_1762598_8 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000508 134.0
REGS3_k127_1762598_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000009178 102.0
REGS3_k127_1777440_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 348.0
REGS3_k127_1777440_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 304.0
REGS3_k127_1777440_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
REGS3_k127_1777440_3 spore germination - GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:1901682,GO:1903825,GO:1905039 - 0.00073 44.0
REGS3_k127_1779615_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1356.0
REGS3_k127_1779615_1 Neisseria PilC beta-propeller domain K02674 - - 5.282e-247 820.0
REGS3_k127_1779615_10 Type II transport protein GspH K08084 - - 0.000000000000000000000000004632 121.0
REGS3_k127_1779615_11 Pilus assembly protein PilX - - - 0.0000000000000000000002864 110.0
REGS3_k127_1779615_12 CbiX K03795 - 4.99.1.3 0.0000000001079 63.0
REGS3_k127_1779615_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 471.0
REGS3_k127_1779615_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 375.0
REGS3_k127_1779615_4 PFAM oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 327.0
REGS3_k127_1779615_5 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000000000000000000000000000000000000000723 207.0
REGS3_k127_1779615_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000004949 166.0
REGS3_k127_1779615_7 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000004239 140.0
REGS3_k127_1779615_8 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000001015 128.0
REGS3_k127_1779615_9 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000002957 117.0
REGS3_k127_1791944_0 type II secretion system protein E K02454,K02652,K12276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 537.0
REGS3_k127_1791944_1 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 433.0
REGS3_k127_1791944_2 - - - - 0.0000000003247 64.0
REGS3_k127_1793179_0 PQQ enzyme repeat - - - 4.646e-215 677.0
REGS3_k127_1793179_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 582.0
REGS3_k127_1793179_2 amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 422.0
REGS3_k127_1793179_3 aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 403.0
REGS3_k127_1793179_4 - - - - 0.000000000000000000000000000000000000000000002063 175.0
REGS3_k127_1793179_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000164 118.0
REGS3_k127_1793179_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001166 102.0
REGS3_k127_1793179_7 Belongs to the ompA family - - - 0.0000002533 60.0
REGS3_k127_1797263_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 6.281e-202 639.0
REGS3_k127_1797263_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 585.0
REGS3_k127_1797263_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 447.0
REGS3_k127_1797263_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 324.0
REGS3_k127_1797263_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 321.0
REGS3_k127_1797263_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 285.0
REGS3_k127_1797263_6 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000004806 126.0
REGS3_k127_1809215_0 PFAM ABC transporter K06158 - - 8.222e-235 743.0
REGS3_k127_1809215_1 MMPL family - - - 1.504e-222 715.0
REGS3_k127_1809215_10 MltA-interacting protein MipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004534 277.0
REGS3_k127_1809215_11 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000046 264.0
REGS3_k127_1809215_12 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
REGS3_k127_1809215_13 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001561 241.0
REGS3_k127_1809215_14 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000002375 197.0
REGS3_k127_1809215_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000003787 173.0
REGS3_k127_1809215_16 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000001368 135.0
REGS3_k127_1809215_17 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000005874 128.0
REGS3_k127_1809215_18 membrane - - - 0.00000000000000000000000000000001102 135.0
REGS3_k127_1809215_19 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000003863 124.0
REGS3_k127_1809215_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 553.0
REGS3_k127_1809215_20 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.0000000000000000000000002222 109.0
REGS3_k127_1809215_21 - - - - 0.00000000000000001034 86.0
REGS3_k127_1809215_22 - - - - 0.00000002354 57.0
REGS3_k127_1809215_23 Resolvase, N terminal domain - - - 0.000001835 49.0
REGS3_k127_1809215_24 FabA-like domain - - - 0.00006811 55.0
REGS3_k127_1809215_3 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 511.0
REGS3_k127_1809215_4 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 443.0
REGS3_k127_1809215_5 3-5 exonuclease K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 424.0
REGS3_k127_1809215_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 423.0
REGS3_k127_1809215_7 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 355.0
REGS3_k127_1809215_8 Glycosyltransferase like family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 309.0
REGS3_k127_1809215_9 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 296.0
REGS3_k127_1816886_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 413.0
REGS3_k127_1816886_1 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 266.0
REGS3_k127_1816886_2 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000003273 152.0
REGS3_k127_1816886_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000001373 150.0
REGS3_k127_1824568_0 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 411.0
REGS3_k127_1824568_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 364.0
REGS3_k127_1824568_2 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000417 51.0
REGS3_k127_1829858_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1808.0
REGS3_k127_1829858_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 1.935e-258 806.0
REGS3_k127_1829858_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 524.0
REGS3_k127_1829858_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 477.0
REGS3_k127_1829858_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 310.0
REGS3_k127_1829858_5 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 316.0
REGS3_k127_1829858_6 - - - - 0.000000000000000000000000000000000000000002551 164.0
REGS3_k127_1829858_7 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000009531 142.0
REGS3_k127_1829858_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000004061 102.0
REGS3_k127_1833968_0 Short chain fatty acid transporter K02106 - - 6.87e-205 647.0
REGS3_k127_1833968_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 563.0
REGS3_k127_1833968_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002794 243.0
REGS3_k127_1833968_3 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000001674 238.0
REGS3_k127_1833968_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000005507 109.0
REGS3_k127_1833968_5 ThiS family K03636 - - 0.00000000000000000002113 102.0
REGS3_k127_18354_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 493.0
REGS3_k127_18354_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 408.0
REGS3_k127_18354_2 Protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 396.0
REGS3_k127_18354_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 323.0
REGS3_k127_18354_4 phosphonate ABC transporter, inner membrane subunit K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 329.0
REGS3_k127_18354_5 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 307.0
REGS3_k127_18354_6 membrane lipoprotein lipid attachment site K07337 - - 0.00000000000000000000000000000000000000000000000000000000004732 213.0
REGS3_k127_18354_7 Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000005544 183.0
REGS3_k127_18354_8 Protein of unknown function (DUF1425) - - - 0.000000000000000008119 89.0
REGS3_k127_184098_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 534.0
REGS3_k127_184098_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 442.0
REGS3_k127_184098_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
REGS3_k127_1842706_0 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.0000000000000000000000000000000000000000000000000000000002606 205.0
REGS3_k127_1842706_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000007584 200.0
REGS3_k127_1842706_2 - - - - 0.0000000000000000000000000000000000001414 151.0
REGS3_k127_184536_0 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 529.0
REGS3_k127_184536_1 belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 349.0
REGS3_k127_184536_2 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 303.0
REGS3_k127_184536_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001487 284.0
REGS3_k127_184536_4 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000001716 147.0
REGS3_k127_184536_5 Uncharacterized protein conserved in bacteria (DUF2322) - - - 0.000000000000000000000000000001256 124.0
REGS3_k127_184536_6 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000007007 105.0
REGS3_k127_184536_7 Protein of unknown function (DUF2946) - - - 0.0004857 43.0
REGS3_k127_1850687_0 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
REGS3_k127_1850687_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
REGS3_k127_1850687_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000007883 201.0
REGS3_k127_1850687_3 TIGRFAM endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000002721 175.0
REGS3_k127_1850687_4 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000001679 171.0
REGS3_k127_1853843_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1087.0
REGS3_k127_1853843_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 569.0
REGS3_k127_1853843_2 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000004305 138.0
REGS3_k127_1864959_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 504.0
REGS3_k127_1864959_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 375.0
REGS3_k127_1871540_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 404.0
REGS3_k127_1871540_1 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000001156 233.0
REGS3_k127_1871540_2 - - - - 0.00000000000000000000000000000000000465 139.0
REGS3_k127_1871540_3 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000003922 144.0
REGS3_k127_1881178_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 359.0
REGS3_k127_1881178_1 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 328.0
REGS3_k127_1881178_2 KDPG and KHG aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000001961 244.0
REGS3_k127_1881178_3 Cupin 2, conserved barrel domain protein - - - 0.000002842 56.0
REGS3_k127_1897338_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 353.0
REGS3_k127_1897338_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001614 284.0
REGS3_k127_1897338_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000007405 194.0
REGS3_k127_1897338_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000004625 192.0
REGS3_k127_1897338_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000004968 197.0
REGS3_k127_1897338_5 ARD/ARD' family - - - 0.00000000000000000000000000000000005654 138.0
REGS3_k127_1897338_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001415 146.0
REGS3_k127_1898496_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1076.0
REGS3_k127_1898496_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 5.597e-220 688.0
REGS3_k127_1898496_10 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 402.0
REGS3_k127_1898496_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 398.0
REGS3_k127_1898496_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 390.0
REGS3_k127_1898496_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 382.0
REGS3_k127_1898496_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 362.0
REGS3_k127_1898496_15 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 308.0
REGS3_k127_1898496_16 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 280.0
REGS3_k127_1898496_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006387 276.0
REGS3_k127_1898496_18 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000001474 246.0
REGS3_k127_1898496_19 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000005858 196.0
REGS3_k127_1898496_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 603.0
REGS3_k127_1898496_20 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000003217 146.0
REGS3_k127_1898496_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000001116 119.0
REGS3_k127_1898496_22 protein conserved in bacteria K09937 - - 0.000000000000000004345 85.0
REGS3_k127_1898496_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 600.0
REGS3_k127_1898496_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 519.0
REGS3_k127_1898496_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 512.0
REGS3_k127_1898496_6 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 512.0
REGS3_k127_1898496_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 499.0
REGS3_k127_1898496_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 483.0
REGS3_k127_1898496_9 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 409.0
REGS3_k127_190885_0 Major facilitator superfamily MFS_1 K08194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 588.0
REGS3_k127_190885_1 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000007939 173.0
REGS3_k127_1914791_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.903e-307 957.0
REGS3_k127_1914791_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000002007 169.0
REGS3_k127_1914791_2 transposase activity - - - 0.0000001062 57.0
REGS3_k127_1914791_3 TIGRFAM conserved - - - 0.0007178 45.0
REGS3_k127_19585_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 607.0
REGS3_k127_19585_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000001117 224.0
REGS3_k127_19585_2 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000000000000000000008209 180.0
REGS3_k127_19585_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000291 185.0
REGS3_k127_196259_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 490.0
REGS3_k127_196259_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 327.0
REGS3_k127_196259_2 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 320.0
REGS3_k127_196259_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000000000005498 162.0
REGS3_k127_196259_4 Outer membrane efflux protein K12340 - - 0.0000007245 51.0
REGS3_k127_1963248_0 Hydantoinase/oxoprolinase - - - 8.154e-310 964.0
REGS3_k127_1963248_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02035 - - 2.151e-247 777.0
REGS3_k127_1963248_10 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 299.0
REGS3_k127_1963248_11 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001909 256.0
REGS3_k127_1963248_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000003606 151.0
REGS3_k127_1963248_13 MAPEG family - - - 0.0000000000000000000000000000005157 127.0
REGS3_k127_1963248_14 NIPSNAP - - - 0.00000000000000000000000000000197 123.0
REGS3_k127_1963248_15 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.00000000000000000000000002574 113.0
REGS3_k127_1963248_16 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000534 112.0
REGS3_k127_1963248_17 - - - - 0.0000000000000000007929 92.0
REGS3_k127_1963248_18 - - - - 0.0000000000005553 73.0
REGS3_k127_1963248_19 - - - - 0.00000000006976 74.0
REGS3_k127_1963248_2 C4-dicarboxylate transmembrane transporter activity - - - 2.459e-209 657.0
REGS3_k127_1963248_20 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02035 - - 0.000000001123 62.0
REGS3_k127_1963248_3 Dienelactone hydrolase family K01061 - 3.1.1.45 1.613e-195 618.0
REGS3_k127_1963248_4 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 496.0
REGS3_k127_1963248_5 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 457.0
REGS3_k127_1963248_6 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 422.0
REGS3_k127_1963248_7 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 388.0
REGS3_k127_1963248_8 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 338.0
REGS3_k127_1963248_9 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 314.0
REGS3_k127_2099214_0 Phosphoesterase family - - - 7.759e-205 649.0
REGS3_k127_2099214_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 515.0
REGS3_k127_2099214_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
REGS3_k127_2099214_3 - - - - 0.00000003321 63.0
REGS3_k127_2099214_4 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000002392 52.0
REGS3_k127_2102564_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 626.0
REGS3_k127_2102564_1 succinylglutamate desuccinylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 395.0
REGS3_k127_2102564_2 glutathione s-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 307.0
REGS3_k127_2102564_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000001892 191.0
REGS3_k127_2102564_4 Cupin domain - - - 0.0000000000000000000000000000000000000000009609 159.0
REGS3_k127_2102564_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000003612 61.0
REGS3_k127_215768_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 8.08e-216 675.0
REGS3_k127_215768_1 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 547.0
REGS3_k127_215768_10 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 316.0
REGS3_k127_215768_11 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 315.0
REGS3_k127_215768_12 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 301.0
REGS3_k127_215768_13 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 318.0
REGS3_k127_215768_14 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 293.0
REGS3_k127_215768_15 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000003434 263.0
REGS3_k127_215768_16 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000001749 243.0
REGS3_k127_215768_17 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000004976 245.0
REGS3_k127_215768_18 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000003457 239.0
REGS3_k127_215768_19 phosphatase, C-terminal domain of histone macro H2A1 like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
REGS3_k127_215768_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 544.0
REGS3_k127_215768_20 TPM domain K08988 - - 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
REGS3_k127_215768_21 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000008794 198.0
REGS3_k127_215768_22 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000005147 151.0
REGS3_k127_215768_23 Cupredoxin-like domain - - - 0.00000000000000000000001212 104.0
REGS3_k127_215768_3 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 533.0
REGS3_k127_215768_4 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 496.0
REGS3_k127_215768_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 483.0
REGS3_k127_215768_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 471.0
REGS3_k127_215768_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 398.0
REGS3_k127_215768_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 354.0
REGS3_k127_215768_9 response regulator K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 340.0
REGS3_k127_2188509_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1178.0
REGS3_k127_2188509_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.273e-221 694.0
REGS3_k127_2188509_10 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000005613 225.0
REGS3_k127_2188509_11 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000003111 200.0
REGS3_k127_2188509_12 Haem-degrading - - - 0.000000000000000000000000000000003439 135.0
REGS3_k127_2188509_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 5.064e-194 635.0
REGS3_k127_2188509_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 455.0
REGS3_k127_2188509_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 389.0
REGS3_k127_2188509_5 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 372.0
REGS3_k127_2188509_6 Periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 358.0
REGS3_k127_2188509_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 321.0
REGS3_k127_2188509_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 308.0
REGS3_k127_2188509_9 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 299.0
REGS3_k127_223373_0 Biotin carboxylase C-terminal domain - - - 0.0 1287.0
REGS3_k127_223373_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 480.0
REGS3_k127_223373_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 374.0
REGS3_k127_223373_4 - - - - 0.00000000000000842 79.0
REGS3_k127_223373_5 - - - - 0.000002018 52.0
REGS3_k127_2234840_0 PFAM ABC-1 domain protein K03688 - - 1.867e-202 644.0
REGS3_k127_2234840_1 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 362.0
REGS3_k127_2234840_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000008077 173.0
REGS3_k127_2234840_3 Cytochrome c - - - 0.0000000000000002848 85.0
REGS3_k127_2234840_4 SIS domain K00820 - 2.6.1.16 0.0000000000001451 74.0
REGS3_k127_2269596_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 409.0
REGS3_k127_2269596_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006871 263.0
REGS3_k127_2269596_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000001854 166.0
REGS3_k127_2318876_0 Polysaccharide biosynthesis protein - - - 1.155e-209 662.0
REGS3_k127_2318876_1 family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
REGS3_k127_2318876_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
REGS3_k127_2318876_3 O-Antigen ligase - - - 0.0000000000000000000000000000000413 140.0
REGS3_k127_2384137_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1746.0
REGS3_k127_2384137_1 MgtE intracellular N domain K06213 - - 6.686e-217 681.0
REGS3_k127_2384137_2 Belongs to the amidase family K01426 - 3.5.1.4 1.078e-210 663.0
REGS3_k127_2384137_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007998 263.0
REGS3_k127_2384137_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003638 261.0
REGS3_k127_2384137_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001859 255.0
REGS3_k127_2384137_6 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000001041 192.0
REGS3_k127_2384137_7 Predicted membrane protein (DUF2214) K08983 - - 0.000000000000000000000000001641 117.0
REGS3_k127_2384137_8 Domain of unknown function (DUF4440) - - - 0.0000000000000000232 87.0
REGS3_k127_2425231_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.56e-321 992.0
REGS3_k127_2425231_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.372e-273 845.0
REGS3_k127_2425231_10 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 407.0
REGS3_k127_2425231_11 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 330.0
REGS3_k127_2425231_12 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000002519 231.0
REGS3_k127_2425231_13 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000054 232.0
REGS3_k127_2425231_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
REGS3_k127_2425231_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000002471 194.0
REGS3_k127_2425231_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000000001701 186.0
REGS3_k127_2425231_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000005047 158.0
REGS3_k127_2425231_18 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000007243 113.0
REGS3_k127_2425231_19 ATP synthase I chain K02116 - - 0.000000000000000000008616 96.0
REGS3_k127_2425231_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.557e-270 838.0
REGS3_k127_2425231_20 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000005168 80.0
REGS3_k127_2425231_21 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000369 70.0
REGS3_k127_2425231_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 7.284e-201 635.0
REGS3_k127_2425231_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.295e-198 633.0
REGS3_k127_2425231_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 608.0
REGS3_k127_2425231_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 503.0
REGS3_k127_2425231_7 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 457.0
REGS3_k127_2425231_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 462.0
REGS3_k127_2425231_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 442.0
REGS3_k127_2452961_0 Domain of unknown function (DUF3400) - - - 0.0 1844.0
REGS3_k127_2452961_1 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 500.0
REGS3_k127_2452961_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 374.0
REGS3_k127_2452961_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000005365 223.0
REGS3_k127_2452961_4 membrane - - - 0.00000000000000000000000000000000000000007271 156.0
REGS3_k127_2452961_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000001614 155.0
REGS3_k127_2452961_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000006464 144.0
REGS3_k127_2477749_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 537.0
REGS3_k127_2477749_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 478.0
REGS3_k127_2477749_2 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000004648 224.0
REGS3_k127_2477749_3 6,7-dimethyl-8-ribityllumazine synthase K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000003798 211.0
REGS3_k127_2477749_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000004328 186.0
REGS3_k127_2477749_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000001907 162.0
REGS3_k127_2497653_0 Aldo/keto reductase family K00064 - 1.1.1.122 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 366.0
REGS3_k127_2497653_1 KR domain K22185 - 1.1.1.175 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 321.0
REGS3_k127_2497653_2 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 289.0
REGS3_k127_2497653_3 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000279 258.0
REGS3_k127_2497653_4 DoxX K15977 - - 0.000000000000000000000000000000000000003688 151.0
REGS3_k127_2497653_5 Putative DNA-binding domain - - - 0.000000000005925 70.0
REGS3_k127_2497653_6 Belongs to the RbsD FucU family K02431 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0030246,GO:0036094,GO:0042806,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0048029,GO:0071704 5.1.3.29 0.000000000159 68.0
REGS3_k127_2510687_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 562.0
REGS3_k127_2510687_1 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 484.0
REGS3_k127_2510687_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 424.0
REGS3_k127_2510687_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 311.0
REGS3_k127_2510687_4 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 301.0
REGS3_k127_2510687_5 (ABC) transporter - - - 0.000000000004624 78.0
REGS3_k127_2510687_6 PEP-CTERM motif - - - 0.0000004386 55.0
REGS3_k127_25351_0 PFAM glucose-methanol-choline oxidoreductase K03333 - 1.1.3.6 5.498e-283 880.0
REGS3_k127_25351_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.352e-255 800.0
REGS3_k127_25351_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 6.752e-216 676.0
REGS3_k127_25351_3 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 348.0
REGS3_k127_25351_4 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 340.0
REGS3_k127_25351_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002093 264.0
REGS3_k127_25351_6 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002678 270.0
REGS3_k127_25351_7 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000004759 189.0
REGS3_k127_25351_8 - - - - 0.00000000000000000000003937 103.0
REGS3_k127_25351_9 DoxX K15977 - - 0.0000002511 56.0
REGS3_k127_257027_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.246e-244 756.0
REGS3_k127_257027_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 1.149e-217 689.0
REGS3_k127_257027_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000003734 229.0
REGS3_k127_257027_11 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000005248 214.0
REGS3_k127_257027_12 PFAM response regulator receiver K15012 - - 0.00000000000000000000000000000000000000000000000000000001798 217.0
REGS3_k127_257027_13 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000006161 194.0
REGS3_k127_257027_14 sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000004054 173.0
REGS3_k127_257027_15 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.0000000000000000000000000000000000000004805 155.0
REGS3_k127_257027_16 stringent starvation protein b K03600 - - 0.00000000000000000000000000000000000002032 152.0
REGS3_k127_257027_17 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000002338 137.0
REGS3_k127_257027_18 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000000000000000000000000002397 139.0
REGS3_k127_257027_19 Cytochrome C oxidase, cbb3-type, subunit III K17223 - - 0.0000000000000000000000000000002636 128.0
REGS3_k127_257027_2 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 485.0
REGS3_k127_257027_20 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000001987 115.0
REGS3_k127_257027_21 Rhodanese Homology Domain - - - 0.0000000000000000000001437 103.0
REGS3_k127_257027_22 - - - - 0.0004353 44.0
REGS3_k127_257027_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 474.0
REGS3_k127_257027_4 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 354.0
REGS3_k127_257027_5 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 347.0
REGS3_k127_257027_6 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 350.0
REGS3_k127_257027_7 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 295.0
REGS3_k127_257027_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 286.0
REGS3_k127_257027_9 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002642 270.0
REGS3_k127_2584993_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.0 1061.0
REGS3_k127_2584993_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 544.0
REGS3_k127_2584993_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 355.0
REGS3_k127_2584993_3 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002246 229.0
REGS3_k127_2584993_4 S-adenosyl-L-methionine-dependent methyltransferase K15461 - 2.1.1.61 0.0000000000000000000000000000000003531 134.0
REGS3_k127_2584993_5 - - - - 0.00000000000000000012 89.0
REGS3_k127_2584993_6 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000002812 73.0
REGS3_k127_2589166_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 359.0
REGS3_k127_2589166_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 313.0
REGS3_k127_2589166_2 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000000000000009513 228.0
REGS3_k127_2589498_0 Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide K01426 - 3.5.1.4 7.537e-215 668.0
REGS3_k127_2589498_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 556.0
REGS3_k127_2589498_2 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 503.0
REGS3_k127_2589498_3 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 467.0
REGS3_k127_2589498_4 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 417.0
REGS3_k127_2589498_5 abc transporter atp-binding protein K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 357.0
REGS3_k127_2589498_6 ABC transporter ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 326.0
REGS3_k127_2589498_7 UreE urease accessory protein, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000005264 183.0
REGS3_k127_2589498_8 Transcription antitermination protein - - - 0.000000000000000000000000000000000000001318 151.0
REGS3_k127_2589498_9 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000004888 110.0
REGS3_k127_2594026_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 4.941e-204 645.0
REGS3_k127_2594026_1 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 548.0
REGS3_k127_2594026_2 ATPases associated with a variety of cellular activities K01996,K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 352.0
REGS3_k127_2594026_3 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 343.0
REGS3_k127_2594026_4 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.0000000000000000000000000000000000000000007893 158.0
REGS3_k127_2594031_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 7.581e-259 801.0
REGS3_k127_2594031_1 Transketolase, thiamine diphosphate binding domain - - - 1.565e-228 726.0
REGS3_k127_2594031_2 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 584.0
REGS3_k127_2594031_3 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 514.0
REGS3_k127_2594031_4 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 509.0
REGS3_k127_2594031_5 Bacterial transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 381.0
REGS3_k127_2594507_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 403.0
REGS3_k127_2594507_1 Polyprenyl synthetase K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 390.0
REGS3_k127_2594507_2 ABC-type transport auxiliary lipoprotein component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 237.0
REGS3_k127_2600936_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 409.0
REGS3_k127_2600936_1 Von Willebrand factor type A - - - 0.0000000000000000000001336 100.0
REGS3_k127_2607341_0 Tryptophan halogenase K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 408.0
REGS3_k127_2607341_1 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 302.0
REGS3_k127_2607341_2 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000006235 265.0
REGS3_k127_2607341_3 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000005416 210.0
REGS3_k127_2607341_4 nUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000007181 197.0
REGS3_k127_2607341_5 - - - - 0.00000000000000000000000000000000000000000000000007348 187.0
REGS3_k127_2607341_6 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000001677 87.0
REGS3_k127_2607341_7 - - - - 0.00000000000000002356 83.0
REGS3_k127_2607341_8 Methyltransferase domain - - - 0.00000005122 56.0
REGS3_k127_2635509_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 389.0
REGS3_k127_2635509_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
REGS3_k127_2635509_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001278 267.0
REGS3_k127_2635509_3 - - - - 0.00000000000000000000000000000000000000001708 159.0
REGS3_k127_2638716_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.766e-203 640.0
REGS3_k127_2638716_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 462.0
REGS3_k127_2638716_2 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 435.0
REGS3_k127_2638716_3 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 426.0
REGS3_k127_2638716_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
REGS3_k127_2638716_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000007259 142.0
REGS3_k127_2646738_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0 1021.0
REGS3_k127_2646738_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 351.0
REGS3_k127_2646738_2 Transposase - - - 0.00000000000000000000000000000000000000000000000000000001084 209.0
REGS3_k127_2646738_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000006653 194.0
REGS3_k127_2651167_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 9.58e-215 683.0
REGS3_k127_2651167_1 Belongs to the amidase family K01426 - 3.5.1.4 1.602e-209 660.0
REGS3_k127_2651167_2 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 488.0
REGS3_k127_2651167_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 415.0
REGS3_k127_2657187_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1328.0
REGS3_k127_2657187_1 Major Facilitator Superfamily - - - 2.209e-215 677.0
REGS3_k127_2657187_10 AcrB/AcrD/AcrF family K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005881 260.0
REGS3_k127_2657187_11 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000001052 227.0
REGS3_k127_2657187_12 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000006302 188.0
REGS3_k127_2657187_13 membrane - - - 0.000000000000000000000000000000000000008714 149.0
REGS3_k127_2657187_14 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000005684 151.0
REGS3_k127_2657187_15 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000006879 100.0
REGS3_k127_2657187_16 Protein of unknown function (DUF2914) - - - 0.000001358 56.0
REGS3_k127_2657187_2 Amidohydrolase K07045 - - 2.216e-214 676.0
REGS3_k127_2657187_3 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 3.138e-208 659.0
REGS3_k127_2657187_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 546.0
REGS3_k127_2657187_5 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 529.0
REGS3_k127_2657187_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 383.0
REGS3_k127_2657187_7 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 324.0
REGS3_k127_2657187_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 316.0
REGS3_k127_2657187_9 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 299.0
REGS3_k127_2663455_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 4.149e-233 732.0
REGS3_k127_2663455_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 450.0
REGS3_k127_2663455_2 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 383.0
REGS3_k127_2663455_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 360.0
REGS3_k127_2663455_4 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000001256 195.0
REGS3_k127_2663455_5 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000001161 194.0
REGS3_k127_2663455_6 protein conserved in bacteria K03690 - - 0.000000000000000000000000000000002866 136.0
REGS3_k127_2674413_0 Circularly permuted ATP-grasp type 2 - - - 4.894e-244 760.0
REGS3_k127_2674413_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 383.0
REGS3_k127_2674413_2 - K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 293.0
REGS3_k127_2674413_3 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
REGS3_k127_2674413_4 Trypsin - - - 0.00000000000000000001993 94.0
REGS3_k127_2675621_0 PERMEase K06901 - - 2.528e-208 660.0
REGS3_k127_2675621_1 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 595.0
REGS3_k127_2675621_2 CoA-ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 473.0
REGS3_k127_2675621_3 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 385.0
REGS3_k127_2675621_4 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000001994 185.0
REGS3_k127_2675621_5 - - - - 0.0000000000000000000001062 100.0
REGS3_k127_2675621_6 Protein of unknown function (DUF2877) - - - 0.000000000000000013 93.0
REGS3_k127_2681462_0 Malic enzyme K00029 - 1.1.1.40 0.0 1116.0
REGS3_k127_2681462_1 Aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.495e-229 719.0
REGS3_k127_2681462_2 hmm pf00005 K06147,K11085 - - 7.019e-222 704.0
REGS3_k127_2681462_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 573.0
REGS3_k127_2681462_4 Bacterial extracellular solute-binding protein K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 318.0
REGS3_k127_2681462_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000004357 226.0
REGS3_k127_2681462_6 ABC-2 type transporter K01992 - - 0.000000000000941 68.0
REGS3_k127_2694969_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 533.0
REGS3_k127_2694969_1 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 360.0
REGS3_k127_2694969_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 318.0
REGS3_k127_2694969_3 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000008836 170.0
REGS3_k127_2698284_0 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 530.0
REGS3_k127_2698284_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 397.0
REGS3_k127_2698284_2 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 331.0
REGS3_k127_2698284_3 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000000000000000001217 212.0
REGS3_k127_2698284_4 Universal stress protein family - - - 0.0000000000000000000000000000000001019 138.0
REGS3_k127_2698284_5 - - - - 0.00000000000000000000000000000005799 131.0
REGS3_k127_2698284_6 Polymer-forming cytoskeletal - - - 0.0000000000000000000004453 109.0
REGS3_k127_2698284_7 Cupin - - - 0.0000000000000000001132 96.0
REGS3_k127_2698284_8 Gram-negative bacterial TonB protein C-terminal - - - 0.00000007309 63.0
REGS3_k127_2715684_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1144.0
REGS3_k127_2715684_1 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 469.0
REGS3_k127_2715684_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 377.0
REGS3_k127_2715684_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000007397 234.0
REGS3_k127_2715684_4 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000001852 228.0
REGS3_k127_2715684_5 SMART cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000006167 224.0
REGS3_k127_2715684_6 PFAM regulatory protein AsnC Lrp family K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000004113 206.0
REGS3_k127_2723603_0 Exopolysaccharide biosynthesis protein YbjH - - - 4.089e-240 774.0
REGS3_k127_2723603_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000002185 229.0
REGS3_k127_2723603_2 B12 binding domain - - - 0.0000000000000000000008259 100.0
REGS3_k127_2725551_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1744.0
REGS3_k127_2725551_1 Domain of unknown function (DUF4070) - - - 4.88e-221 696.0
REGS3_k127_2725551_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.095e-213 678.0
REGS3_k127_2725551_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 466.0
REGS3_k127_2725551_4 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 332.0
REGS3_k127_2725551_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 292.0
REGS3_k127_2725551_6 TIGRFAM type I secretion membrane fusion protein, HlyD - - - 0.0000000000392 66.0
REGS3_k127_2730158_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 4.315e-272 858.0
REGS3_k127_2730158_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.137e-248 784.0
REGS3_k127_2730158_10 NfeD-like C-terminal, partner-binding - - - 0.0000000000000005321 84.0
REGS3_k127_2730158_11 - - - - 0.000000004753 60.0
REGS3_k127_2730158_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 513.0
REGS3_k127_2730158_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 398.0
REGS3_k127_2730158_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 393.0
REGS3_k127_2730158_5 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 359.0
REGS3_k127_2730158_6 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 300.0
REGS3_k127_2730158_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008019 271.0
REGS3_k127_2730158_8 Belongs to the ompA family - - - 0.00000000000000000000000000000001399 136.0
REGS3_k127_2730158_9 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000006371 128.0
REGS3_k127_2735381_0 DNA helicase K03654 - 3.6.4.12 5.579e-273 851.0
REGS3_k127_2735381_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 534.0
REGS3_k127_2735381_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000001001 229.0
REGS3_k127_2735381_11 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000006444 228.0
REGS3_k127_2735381_12 MAPEG family - - - 0.000000000000000000000000000000000000000004906 158.0
REGS3_k127_2735381_13 Transporter, small conductance mechanosensitive ion channel MscS family protein - - - 0.000000000000000000000000000000000000763 151.0
REGS3_k127_2735381_15 Domain of unknown function (DUF1840) - - - 0.00000000000000000000007344 101.0
REGS3_k127_2735381_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000007582 86.0
REGS3_k127_2735381_17 AMP-binding enzyme C-terminal domain K00666 - - 0.00002848 49.0
REGS3_k127_2735381_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 391.0
REGS3_k127_2735381_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 348.0
REGS3_k127_2735381_4 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 341.0
REGS3_k127_2735381_5 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 291.0
REGS3_k127_2735381_6 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001002 280.0
REGS3_k127_2735381_7 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
REGS3_k127_2735381_8 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000008157 237.0
REGS3_k127_2735381_9 Carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000000001083 239.0
REGS3_k127_2737842_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 457.0
REGS3_k127_2737842_1 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 430.0
REGS3_k127_2737842_2 Phosphopantetheine attachment site K02078 - - 0.0000000000002729 74.0
REGS3_k127_2751222_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 1.03e-226 718.0
REGS3_k127_2751222_1 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 453.0
REGS3_k127_2751222_2 PFAM beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 271.0
REGS3_k127_2751222_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003913 248.0
REGS3_k127_2751222_4 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000006031 189.0
REGS3_k127_2751222_5 - - - - 0.000000000000000000000000000000000000000000000005459 179.0
REGS3_k127_2751222_6 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000007294 156.0
REGS3_k127_2752381_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.808e-286 888.0
REGS3_k127_2752381_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 571.0
REGS3_k127_2752381_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 355.0
REGS3_k127_2752381_3 urease activity K01429,K14048 - 3.5.1.5 0.0000000000000003206 80.0
REGS3_k127_2753498_0 - Amino acid transport and metabolism K01953 - 6.3.5.4 5.625e-238 751.0
REGS3_k127_2753498_1 Heparinase II/III N-terminus - - - 1.678e-210 676.0
REGS3_k127_2753498_10 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000004346 206.0
REGS3_k127_2753498_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000000000000147 128.0
REGS3_k127_2753498_12 Polysaccharide biosynthesis protein - - - 0.00000000000000000000002018 115.0
REGS3_k127_2753498_2 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 487.0
REGS3_k127_2753498_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 378.0
REGS3_k127_2753498_4 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 301.0
REGS3_k127_2753498_5 G-rich domain on putative tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 300.0
REGS3_k127_2753498_6 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006755 258.0
REGS3_k127_2753498_7 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000205 267.0
REGS3_k127_2753498_8 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001345 259.0
REGS3_k127_2753498_9 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000003351 219.0
REGS3_k127_2764623_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 627.0
REGS3_k127_2764623_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 370.0
REGS3_k127_2764623_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
REGS3_k127_2764623_3 Protein of unknown function (DUF3034) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 328.0
REGS3_k127_2764623_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000108 216.0
REGS3_k127_2764623_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000002606 200.0
REGS3_k127_2764623_6 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000001369 196.0
REGS3_k127_2764623_7 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000325 153.0
REGS3_k127_2764623_8 Bacterial-like globin K06886 - - 0.0000000000000000000000000000007314 130.0
REGS3_k127_2790406_0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 8.426e-227 706.0
REGS3_k127_2790406_1 von Willebrand factor, type A - - - 9.808e-207 667.0
REGS3_k127_2790406_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 451.0
REGS3_k127_2790406_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K19837 - 3.5.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 446.0
REGS3_k127_2790406_4 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000009993 231.0
REGS3_k127_2790406_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000001918 202.0
REGS3_k127_2793455_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1747.0
REGS3_k127_289390_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 551.0
REGS3_k127_289390_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 376.0
REGS3_k127_289390_2 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 350.0
REGS3_k127_289390_3 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001406 283.0
REGS3_k127_289390_4 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000002653 168.0
REGS3_k127_289390_5 Psort location Cytoplasmic, score - - - 0.0000000000000000000000273 106.0
REGS3_k127_289390_6 Domain of unknown function (DUF4139) - - - 0.00000000000000000000004475 100.0
REGS3_k127_289390_7 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.00000000000002202 76.0
REGS3_k127_2950312_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1064.0
REGS3_k127_2950312_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1041.0
REGS3_k127_2950312_10 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 362.0
REGS3_k127_2950312_11 Belongs to the bacterial glucokinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 332.0
REGS3_k127_2950312_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001606 210.0
REGS3_k127_2950312_13 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000008973 176.0
REGS3_k127_2950312_14 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000007996 145.0
REGS3_k127_2950312_15 Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins. K15383 - - 0.0000000000000000005275 96.0
REGS3_k127_2950312_16 Belongs to the ABC transporter superfamily K10112 - - 0.000000000001055 69.0
REGS3_k127_2950312_2 ASPIC and UnbV - - - 5.57e-290 897.0
REGS3_k127_2950312_3 cell adhesion involved in biofilm formation - - - 4.65e-233 731.0
REGS3_k127_2950312_4 Histidine kinase - - - 1.951e-225 724.0
REGS3_k127_2950312_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.778e-198 624.0
REGS3_k127_2950312_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 486.0
REGS3_k127_2950312_7 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 469.0
REGS3_k127_2950312_8 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 415.0
REGS3_k127_2950312_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
REGS3_k127_2954262_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 424.0
REGS3_k127_2954262_1 Cupin - - - 0.0000000000000000000000000000000000000000000000000002464 192.0
REGS3_k127_2954262_2 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000001808 195.0
REGS3_k127_2954262_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000002178 169.0
REGS3_k127_2954262_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000233 124.0
REGS3_k127_2954262_5 Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000168 67.0
REGS3_k127_2966824_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 483.0
REGS3_k127_2966824_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 356.0
REGS3_k127_2966824_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 311.0
REGS3_k127_2966824_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000001122 226.0
REGS3_k127_2966824_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000005106 104.0
REGS3_k127_2979966_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1345.0
REGS3_k127_2979966_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.442e-217 679.0
REGS3_k127_2979966_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 455.0
REGS3_k127_2979966_11 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 420.0
REGS3_k127_2979966_12 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 400.0
REGS3_k127_2979966_13 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 372.0
REGS3_k127_2979966_14 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 357.0
REGS3_k127_2979966_15 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 345.0
REGS3_k127_2979966_16 POTRA domain, FtsQ-type - - - 0.000000000000000000000000000000000000000000000000000000006844 206.0
REGS3_k127_2979966_17 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000001635 123.0
REGS3_k127_2979966_18 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001593 83.0
REGS3_k127_2979966_19 Protein of unknown function (DUF721) - - - 0.0000000000001138 78.0
REGS3_k127_2979966_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.644e-216 680.0
REGS3_k127_2979966_20 - - - - 0.00004913 47.0
REGS3_k127_2979966_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 596.0
REGS3_k127_2979966_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 587.0
REGS3_k127_2979966_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 557.0
REGS3_k127_2979966_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 544.0
REGS3_k127_2979966_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 499.0
REGS3_k127_2979966_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 468.0
REGS3_k127_2979966_9 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 475.0
REGS3_k127_2991600_0 Inner membrane protein CreD K06143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 392.0
REGS3_k127_2991600_1 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000106 136.0
REGS3_k127_2991600_2 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000005384 63.0
REGS3_k127_2991600_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000001831 55.0
REGS3_k127_2993919_0 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 2.023e-233 723.0
REGS3_k127_2993919_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000001649 201.0
REGS3_k127_3012696_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.386e-208 657.0
REGS3_k127_3012696_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 477.0
REGS3_k127_3012696_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 398.0
REGS3_k127_3012696_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 385.0
REGS3_k127_3012696_4 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
REGS3_k127_3012696_5 PFAM regulatory protein TetR K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 290.0
REGS3_k127_3012696_6 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002328 276.0
REGS3_k127_3012696_7 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000000000000002594 179.0
REGS3_k127_3012696_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001057 112.0
REGS3_k127_3012696_9 Virulence factor membrane-bound polymerase, C-terminal - - - 0.000000000000000000001488 102.0
REGS3_k127_3098729_0 Nitric oxide reductase large subunit K04561 - 1.7.2.5 0.0 1037.0
REGS3_k127_3098729_1 Uncharacterized protein family (UPF0051) K09014 - - 5.423e-283 871.0
REGS3_k127_3098729_2 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000007566 219.0
REGS3_k127_3098729_3 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000003788 172.0
REGS3_k127_3108252_0 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
REGS3_k127_3108252_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 401.0
REGS3_k127_3108252_2 PFAM coenzyme PQQ synthesis K06138 - - 0.000000000000000000004092 100.0
REGS3_k127_3108252_3 biosynthesis protein E K06139 - - 0.000000000001224 68.0
REGS3_k127_313957_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1810.0
REGS3_k127_313957_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1064.0
REGS3_k127_313957_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 319.0
REGS3_k127_313957_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
REGS3_k127_313957_12 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000009825 260.0
REGS3_k127_313957_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004108 192.0
REGS3_k127_313957_14 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000000000000000000000000002336 185.0
REGS3_k127_313957_15 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000001966 138.0
REGS3_k127_313957_16 CRS1_YhbY K07574 - - 0.000000000000000000000000000003225 123.0
REGS3_k127_313957_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 6.06e-204 646.0
REGS3_k127_313957_3 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 599.0
REGS3_k127_313957_4 Fumarate reductase flavoprotein C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 597.0
REGS3_k127_313957_5 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 480.0
REGS3_k127_313957_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 437.0
REGS3_k127_313957_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 423.0
REGS3_k127_313957_8 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 415.0
REGS3_k127_313957_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 321.0
REGS3_k127_3221259_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.279e-224 705.0
REGS3_k127_3221259_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 491.0
REGS3_k127_3221259_10 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000002082 103.0
REGS3_k127_3221259_11 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000008315 80.0
REGS3_k127_3221259_2 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 428.0
REGS3_k127_3221259_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 357.0
REGS3_k127_3221259_4 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 350.0
REGS3_k127_3221259_5 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 347.0
REGS3_k127_3221259_6 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 325.0
REGS3_k127_3221259_7 subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001055 263.0
REGS3_k127_3221259_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003245 257.0
REGS3_k127_3221259_9 ApaG domain - - - 0.0000000000000000000000000000000000000000000000000002173 190.0
REGS3_k127_3266595_0 PFAM Pyrrolo-quinoline quinone - - - 3.492e-203 638.0
REGS3_k127_3266595_1 PFAM Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 562.0
REGS3_k127_3266595_2 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 499.0
REGS3_k127_3266595_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
REGS3_k127_3266595_4 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000007574 229.0
REGS3_k127_3266595_5 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000000000000001761 202.0
REGS3_k127_3266595_6 Ferredoxin - - - 0.00000000000000000000000000000000000000005402 152.0
REGS3_k127_3266595_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000006821 107.0
REGS3_k127_3360016_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1064.0
REGS3_k127_3360016_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.265e-217 693.0
REGS3_k127_3360016_10 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000006042 115.0
REGS3_k127_3360016_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 524.0
REGS3_k127_3360016_3 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 478.0
REGS3_k127_3360016_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000005666 226.0
REGS3_k127_3360016_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000004036 203.0
REGS3_k127_3360016_6 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000001347 203.0
REGS3_k127_3360016_7 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000000000000006659 190.0
REGS3_k127_3360016_9 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000003844 133.0
REGS3_k127_3371292_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.234e-303 939.0
REGS3_k127_3371292_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.288e-198 623.0
REGS3_k127_3371292_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 439.0
REGS3_k127_3371292_3 PFAM Endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 352.0
REGS3_k127_3371292_4 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 312.0
REGS3_k127_3371292_5 Nudix hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000001746 209.0
REGS3_k127_3371292_6 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000007202 155.0
REGS3_k127_3371292_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000001792 135.0
REGS3_k127_3371292_8 Regulatory protein, FmdB family - - - 0.0000000000000000000000000002381 119.0
REGS3_k127_3407380_0 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 368.0
REGS3_k127_3407380_1 Protein of unknown function (DUF2946) - - - 0.0000000000000000000000000000000000000000000283 166.0
REGS3_k127_3407380_2 KTSC domain - - - 0.0000000000000002521 80.0
REGS3_k127_3440658_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004299 258.0
REGS3_k127_3440658_1 Taurine dioxygenase K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000008973 226.0
REGS3_k127_3440658_2 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.000000000000000000000000000000000000005717 152.0
REGS3_k127_3446494_0 TRAP transporter solute receptor TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 508.0
REGS3_k127_3446494_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 507.0
REGS3_k127_3446494_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 395.0
REGS3_k127_3446494_3 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 304.0
REGS3_k127_3446494_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002031 283.0
REGS3_k127_3446494_5 Trypsin-like peptidase domain - - - 0.00000002535 62.0
REGS3_k127_3447314_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 440.0
REGS3_k127_3447314_1 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 347.0
REGS3_k127_3447314_2 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000005731 154.0
REGS3_k127_3447314_3 Predicted integral membrane protein (DUF2269) - - - 0.00000000001003 68.0
REGS3_k127_3447314_4 LTXXQ motif family protein - - - 0.000000009352 64.0
REGS3_k127_3448459_0 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 535.0
REGS3_k127_3448459_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 532.0
REGS3_k127_3448459_2 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 309.0
REGS3_k127_3448459_3 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.00000000000000000000000000000000000000000000000000000000000000001246 230.0
REGS3_k127_3448459_4 pteridine-dependent deoxygenase - - - 0.0000000000000000000000000000000000000000000002825 188.0
REGS3_k127_3458324_0 TIGRFAM phosphonate metabolism protein PhnM K06162 - 3.6.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 409.0
REGS3_k127_3458324_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 309.0
REGS3_k127_3458324_2 Protein of unknown function (DUF1045) - - - 0.000000000000000000000000000000000000000000000000000001067 199.0
REGS3_k127_3458324_3 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000001115 178.0
REGS3_k127_3458324_4 Histidinol dehydrogenase K15509 - 1.1.1.308 0.00000000000000000000000000000000000000001276 153.0
REGS3_k127_3458324_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000006129 148.0
REGS3_k127_3458324_6 - - - - 0.000000002353 65.0
REGS3_k127_3477989_0 type IV-A pilus assembly ATPase PilB K02652 - - 3.57e-215 681.0
REGS3_k127_3477989_1 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 469.0
REGS3_k127_3477989_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001424 264.0
REGS3_k127_3477989_3 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000005138 182.0
REGS3_k127_3477989_4 - - - - 0.00000000000000000000000000000000000000008333 169.0
REGS3_k127_3477989_5 - - - - 0.00000000000000000000000000003768 124.0
REGS3_k127_3477989_6 - - - - 0.00000003228 63.0
REGS3_k127_3487706_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.651e-253 787.0
REGS3_k127_3487706_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 3.908e-201 631.0
REGS3_k127_3487706_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 578.0
REGS3_k127_3487706_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 551.0
REGS3_k127_3487706_4 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 377.0
REGS3_k127_3487706_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 357.0
REGS3_k127_3487706_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 311.0
REGS3_k127_3487706_7 - - - - 0.0000000000000000000000000000000000000000000000000000001024 206.0
REGS3_k127_3487706_8 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000003639 136.0
REGS3_k127_3488015_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1595.0
REGS3_k127_3488015_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 1.524e-254 792.0
REGS3_k127_3488015_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001411 264.0
REGS3_k127_3488015_11 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000142 256.0
REGS3_k127_3488015_12 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000216 229.0
REGS3_k127_3488015_13 - - - - 0.000000000000000000000000008795 112.0
REGS3_k127_3488015_14 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000000518 101.0
REGS3_k127_3488015_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000007138 89.0
REGS3_k127_3488015_16 Thioredoxin - - - 0.00000000000000005692 88.0
REGS3_k127_3488015_17 Domain of unknown function (DUF4340) - - - 0.00000000004973 68.0
REGS3_k127_3488015_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 508.0
REGS3_k127_3488015_3 regulatory protein LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 390.0
REGS3_k127_3488015_4 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 389.0
REGS3_k127_3488015_5 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 390.0
REGS3_k127_3488015_6 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 295.0
REGS3_k127_3488015_7 fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 286.0
REGS3_k127_3488015_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 271.0
REGS3_k127_3488015_9 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
REGS3_k127_348831_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1407.0
REGS3_k127_348831_1 Ribonuclease E/G family K08301 - - 5.74e-234 743.0
REGS3_k127_348831_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 539.0
REGS3_k127_348831_3 Benzoate membrane transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 345.0
REGS3_k127_348831_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
REGS3_k127_348831_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000009133 235.0
REGS3_k127_348831_6 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000199 227.0
REGS3_k127_348831_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000004833 193.0
REGS3_k127_348831_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000002935 162.0
REGS3_k127_3497694_0 Polysaccharide chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 458.0
REGS3_k127_3497694_1 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
REGS3_k127_3497694_2 COG0489 ATPases involved in chromosome partitioning K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 302.0
REGS3_k127_3497694_3 Domain of unknown function (DUF4336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001499 241.0
REGS3_k127_3497694_4 COG3547 Transposase and inactivated derivatives K07486 - - 0.0000000000000000000000000000000001908 144.0
REGS3_k127_3497694_5 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 K07485 - - 0.0000000000061 68.0
REGS3_k127_3501895_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1535.0
REGS3_k127_3501895_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.473e-227 709.0
REGS3_k127_3501895_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
REGS3_k127_3501895_3 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000002071 108.0
REGS3_k127_3501895_4 - - - - 0.0000000000000000003202 88.0
REGS3_k127_3501895_5 - - - - 0.0000000000000000003791 93.0
REGS3_k127_3510833_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 607.0
REGS3_k127_3510833_1 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 476.0
REGS3_k127_3510833_2 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 462.0
REGS3_k127_3510833_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 418.0
REGS3_k127_3510833_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003635 269.0
REGS3_k127_3510833_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000002596 153.0
REGS3_k127_3510833_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000005328 142.0
REGS3_k127_3510833_7 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000644 49.0
REGS3_k127_3510833_8 Thioesterase superfamily K07107 - - 0.0002688 47.0
REGS3_k127_3527862_0 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 500.0
REGS3_k127_3527862_1 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 461.0
REGS3_k127_3527862_10 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001257 241.0
REGS3_k127_3527862_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000001339 173.0
REGS3_k127_3527862_12 type III effector K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000000000000000000000000002671 176.0
REGS3_k127_3527862_13 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000004054 145.0
REGS3_k127_3527862_2 PFAM Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 434.0
REGS3_k127_3527862_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 382.0
REGS3_k127_3527862_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
REGS3_k127_3527862_5 Phenylacetic acid catabolic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 340.0
REGS3_k127_3527862_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 330.0
REGS3_k127_3527862_7 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 328.0
REGS3_k127_3527862_8 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 310.0
REGS3_k127_3527862_9 oxidoreductase FAD NAD(P)-binding domain protein K14581 - 1.18.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 307.0
REGS3_k127_3531619_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 312.0
REGS3_k127_3531619_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000004461 141.0
REGS3_k127_3534427_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 1.116e-216 685.0
REGS3_k127_3534427_1 Activates fatty acids by binding to coenzyme A K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 446.0
REGS3_k127_3534427_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
REGS3_k127_3534427_3 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000001343 228.0
REGS3_k127_3535058_0 ABC transporter transmembrane region K06147 - - 3.452e-245 776.0
REGS3_k127_3535058_1 Domain of unknown function (DUF3390) K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 582.0
REGS3_k127_3535058_10 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003135 247.0
REGS3_k127_3535058_11 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000008861 237.0
REGS3_k127_3535058_12 - - - - 0.000000000000000000000000000000000000000001889 164.0
REGS3_k127_3535058_2 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 573.0
REGS3_k127_3535058_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 457.0
REGS3_k127_3535058_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090,K18916 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81,1.20.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 384.0
REGS3_k127_3535058_5 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
REGS3_k127_3535058_6 Beta-lactamase enzyme family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 301.0
REGS3_k127_3535058_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002522 303.0
REGS3_k127_3535058_8 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005567 278.0
REGS3_k127_3535058_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 264.0
REGS3_k127_3536255_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 594.0
REGS3_k127_3536255_1 - - - - 0.00000002226 58.0
REGS3_k127_3541470_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 411.0
REGS3_k127_3541470_1 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 291.0
REGS3_k127_3541470_2 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000005453 173.0
REGS3_k127_3541470_3 protein conserved in bacteria K09780 - - 0.0000000000106 68.0
REGS3_k127_3541470_4 YCII-related domain K09780 - - 0.00000004774 55.0
REGS3_k127_3544729_0 mandelate racemase muconate lactonizing - - - 7.225e-194 611.0
REGS3_k127_3544729_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 553.0
REGS3_k127_3544729_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 374.0
REGS3_k127_3544729_3 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 366.0
REGS3_k127_3544729_4 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.0000000000000000000000000000000000000000000000000000003281 195.0
REGS3_k127_3544729_5 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000000001101 195.0
REGS3_k127_3544729_6 Phosphate starvation-inducible protein, PSIF - - - 0.0000000000000005323 81.0
REGS3_k127_3551847_0 Glycine cleavage system T protein K00302 - 1.5.3.1 0.0 1183.0
REGS3_k127_3551847_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.205e-251 788.0
REGS3_k127_3551847_2 FAD dependent oxidoreductase K00303,K10816 - 1.4.99.5,1.5.3.1 5.79e-229 713.0
REGS3_k127_3551847_3 Glutamine synthetase, catalytic domain K01915,K09470 - 6.3.1.11,6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 466.0
REGS3_k127_3551847_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 458.0
REGS3_k127_3551847_5 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000001774 185.0
REGS3_k127_3551847_6 The glycine cleavage system catalyzes the degradation of glycine K00302,K00305,K00605,K06980 - 1.5.3.1,2.1.2.10 0.00000000000000000000000000000000000000000000009464 179.0
REGS3_k127_3551847_7 PFAM Sarcosine oxidase, delta subunit, heterotetrameric K00304 - 1.5.3.1 0.00000000000000000000000000000000001911 136.0
REGS3_k127_3551847_8 Phosphotransferase System K11189 - - 0.00000000000000000000000000000000008694 134.0
REGS3_k127_3559221_0 dihydropteroate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 563.0
REGS3_k127_3559221_1 Cyclohydrolase (MCH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 413.0
REGS3_k127_3559221_10 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000009748 226.0
REGS3_k127_3559221_11 4-HFC-P synthase - - - 0.0000000000000000000000000000000000000000000000000000001113 210.0
REGS3_k127_3559221_12 Amino acid kinase family - - - 0.0000000000000000000000000000000002542 150.0
REGS3_k127_3559221_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000005046 123.0
REGS3_k127_3559221_14 ATP-grasp domain - - - 0.00000000002352 66.0
REGS3_k127_3559221_2 RimK-like ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 381.0
REGS3_k127_3559221_3 C1 transfer pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 331.0
REGS3_k127_3559221_4 formaldehyde-activating enzyme K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 282.0
REGS3_k127_3559221_5 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005496 266.0
REGS3_k127_3559221_6 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000000000000009497 245.0
REGS3_k127_3559221_7 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000000000000000000000000000002754 235.0
REGS3_k127_3559221_8 PFAM Flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000008209 224.0
REGS3_k127_3559221_9 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000003411 216.0
REGS3_k127_3565659_0 FtsX-like permease family K02004 - - 1.356e-276 879.0
REGS3_k127_3565659_1 Acetamidase/Formamidase family - - - 3.595e-211 667.0
REGS3_k127_3565659_10 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 353.0
REGS3_k127_3565659_11 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 340.0
REGS3_k127_3565659_12 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 342.0
REGS3_k127_3565659_13 L-carnitine dehydratase bile acid-inducible protein F K18289 - 2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 326.0
REGS3_k127_3565659_14 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 299.0
REGS3_k127_3565659_15 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003721 207.0
REGS3_k127_3565659_16 - - - - 0.000000000000000000000000000000000000000000000002284 182.0
REGS3_k127_3565659_17 Histidine kinase K07645 - 2.7.13.3 0.000000000000005664 80.0
REGS3_k127_3565659_18 - - - - 0.000000000009106 69.0
REGS3_k127_3565659_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 608.0
REGS3_k127_3565659_3 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 587.0
REGS3_k127_3565659_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 560.0
REGS3_k127_3565659_5 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 461.0
REGS3_k127_3565659_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 407.0
REGS3_k127_3565659_7 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 401.0
REGS3_k127_3565659_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 376.0
REGS3_k127_3565659_9 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 368.0
REGS3_k127_3576508_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 378.0
REGS3_k127_3576508_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 353.0
REGS3_k127_3576508_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000002453 223.0
REGS3_k127_3580046_0 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000001456 147.0
REGS3_k127_3580046_1 SnoaL-like domain - - - 0.0000000000000002093 86.0
REGS3_k127_358777_0 III protein, CoA-transferase family K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 458.0
REGS3_k127_358777_1 Mediates influx of magnesium ions K03284,K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 446.0
REGS3_k127_358777_2 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 381.0
REGS3_k127_358777_3 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002122 257.0
REGS3_k127_358777_4 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.0000000000000000000000000000000000000000000000008034 181.0
REGS3_k127_358777_5 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000000000000001689 116.0
REGS3_k127_358777_6 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000004574 61.0
REGS3_k127_358777_7 signal transduction protein with EFhand domain - - - 0.0002746 48.0
REGS3_k127_3598201_0 Phosphate transport regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 468.0
REGS3_k127_3598201_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 408.0
REGS3_k127_3620783_0 Sodium hydrogen exchanger K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 553.0
REGS3_k127_3620783_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 299.0
REGS3_k127_3620783_2 - - - - 0.00000000000000000000000000000000000000000000000000000007778 204.0
REGS3_k127_3620783_3 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000459 198.0
REGS3_k127_3620783_4 Protein of unknown function (DUF2798) - - - 0.00000000000000003866 83.0
REGS3_k127_3624432_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1258.0
REGS3_k127_3624432_1 Extracellular solute-binding protein - - - 0.0 1006.0
REGS3_k127_3624432_10 transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 450.0
REGS3_k127_3624432_11 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 447.0
REGS3_k127_3624432_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 409.0
REGS3_k127_3624432_13 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 404.0
REGS3_k127_3624432_14 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 355.0
REGS3_k127_3624432_15 TIGRFAM squalene synthase HpnC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 353.0
REGS3_k127_3624432_16 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 320.0
REGS3_k127_3624432_17 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 310.0
REGS3_k127_3624432_18 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 302.0
REGS3_k127_3624432_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 287.0
REGS3_k127_3624432_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.655e-281 872.0
REGS3_k127_3624432_20 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002298 243.0
REGS3_k127_3624432_21 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
REGS3_k127_3624432_22 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000006684 145.0
REGS3_k127_3624432_23 Thioesterase superfamily K07107 - - 0.0000000000000000000000000000000003678 136.0
REGS3_k127_3624432_24 - - - - 0.0000000000000000001495 93.0
REGS3_k127_3624432_25 - - - - 0.00000000004447 69.0
REGS3_k127_3624432_26 - - - - 0.0000000000466 65.0
REGS3_k127_3624432_28 - - - - 0.00001565 51.0
REGS3_k127_3624432_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 8.469e-247 776.0
REGS3_k127_3624432_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.511e-229 713.0
REGS3_k127_3624432_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 598.0
REGS3_k127_3624432_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 564.0
REGS3_k127_3624432_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
REGS3_k127_3624432_8 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 509.0
REGS3_k127_3624432_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 487.0
REGS3_k127_3638732_0 ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 540.0
REGS3_k127_3638732_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 338.0
REGS3_k127_3638732_2 ribonucleoside-triphosphate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001178 264.0
REGS3_k127_3638732_3 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000000000563 93.0
REGS3_k127_3644450_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 484.0
REGS3_k127_3644450_1 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 319.0
REGS3_k127_3654478_0 Amidase K02433 - 6.3.5.6,6.3.5.7 8.064e-202 638.0
REGS3_k127_3654478_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 577.0
REGS3_k127_3654478_2 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 540.0
REGS3_k127_3654478_3 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP K08682 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576 3.1.4.14 0.0000000000000000000000000000000000000000000000000000000001838 209.0
REGS3_k127_3654478_4 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000001168 97.0
REGS3_k127_3657916_0 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 442.0
REGS3_k127_3657916_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 383.0
REGS3_k127_3657916_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000001345 215.0
REGS3_k127_3657916_3 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000001805 206.0
REGS3_k127_3657916_4 Cytochrome c2 K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000086 66.0
REGS3_k127_3660187_0 GAF domain - - - 6.066e-251 811.0
REGS3_k127_3660187_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 398.0
REGS3_k127_3660187_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 299.0
REGS3_k127_3660187_3 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000000007074 214.0
REGS3_k127_3665698_0 PFAM Phosphate-selective porin O K07221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 351.0
REGS3_k127_3665698_1 Uncharacterized small protein (DUF2292) - - - 0.00000000001861 68.0
REGS3_k127_3666305_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 402.0
REGS3_k127_3666305_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 377.0
REGS3_k127_3666305_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01919,K01955,K03802 - 6.3.2.2,6.3.2.29,6.3.2.30,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 340.0
REGS3_k127_3666305_3 carboxylic acid catabolic process K01856,K19802 - 5.1.1.20,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 320.0
REGS3_k127_3666305_4 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008843 280.0
REGS3_k127_3666305_5 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 281.0
REGS3_k127_3666305_6 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008241 284.0
REGS3_k127_3666305_7 FecR protein - - - 0.000000000000000000000000000000004726 141.0
REGS3_k127_3666305_8 - - - - 0.00000000002064 70.0
REGS3_k127_3695393_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1200.0
REGS3_k127_3695393_1 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 494.0
REGS3_k127_3695393_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 486.0
REGS3_k127_3695393_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 398.0
REGS3_k127_3695393_4 Ribose xylose arabinose galactoside ABC-type transport systems, permease components K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 373.0
REGS3_k127_3695393_5 Ribose xylose arabinose galactoside ABC-type transport systems, permease components K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 346.0
REGS3_k127_3695393_6 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000004987 205.0
REGS3_k127_3695393_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000003337 153.0
REGS3_k127_3695393_8 universal stress protein - - - 0.0000000000000000000000000000000001804 138.0
REGS3_k127_3698471_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 537.0
REGS3_k127_3698471_1 Methyl-transferase K06983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 431.0
REGS3_k127_3698471_2 HD domain K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000008488 234.0
REGS3_k127_3698471_3 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000005513 232.0
REGS3_k127_3698471_4 ABC transporter substrate-binding protein - - - 0.00000008619 54.0
REGS3_k127_3711652_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.706e-258 816.0
REGS3_k127_3711652_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 601.0
REGS3_k127_3711652_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 548.0
REGS3_k127_3711652_3 Fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 461.0
REGS3_k127_3711652_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 336.0
REGS3_k127_3711652_5 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000001046 242.0
REGS3_k127_3711652_6 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000008152 211.0
REGS3_k127_3711652_7 2Fe-2S -binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002047 192.0
REGS3_k127_3714200_0 protease with the C-terminal PDZ domain - - - 8.962e-202 637.0
REGS3_k127_3714200_1 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000002166 202.0
REGS3_k127_3714200_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000005996 84.0
REGS3_k127_3714200_3 PFAM Bacterial OB fold (BOF) protein - - - 0.000007344 53.0
REGS3_k127_371721_0 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 522.0
REGS3_k127_371721_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 436.0
REGS3_k127_371721_2 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 359.0
REGS3_k127_371721_3 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001563 256.0
REGS3_k127_371721_4 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000000000000000001859 169.0
REGS3_k127_3719532_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 410.0
REGS3_k127_3719532_1 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007961 246.0
REGS3_k127_3719532_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000001074 217.0
REGS3_k127_3719532_3 Protein of unknown function (DUF3301) - - - 0.0000000000000000000000000761 111.0
REGS3_k127_3719532_4 - - - - 0.000000000000000000001732 97.0
REGS3_k127_372284_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 448.0
REGS3_k127_372284_1 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 328.0
REGS3_k127_372284_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002588 272.0
REGS3_k127_372284_3 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000005149 61.0
REGS3_k127_3729843_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1163.0
REGS3_k127_3729843_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 597.0
REGS3_k127_3729843_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 377.0
REGS3_k127_3729843_3 Domain of unknown function (DUF4442) - - - 0.0000000000000853 80.0
REGS3_k127_3738782_0 Molecular chaperone. Has ATPase activity K04079 - - 3.06e-321 992.0
REGS3_k127_3738782_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 8.15e-302 937.0
REGS3_k127_3738782_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000002522 169.0
REGS3_k127_3738782_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.593e-235 734.0
REGS3_k127_3738782_3 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 1.806e-218 700.0
REGS3_k127_3738782_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.286e-195 619.0
REGS3_k127_3738782_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 505.0
REGS3_k127_3738782_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 334.0
REGS3_k127_3738782_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000654 264.0
REGS3_k127_3738782_8 Belongs to the enoyl-CoA hydratase isomerase family K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001715 269.0
REGS3_k127_3738782_9 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000001126 228.0
REGS3_k127_3744754_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1303.0
REGS3_k127_3744754_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000001775 118.0
REGS3_k127_3789006_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.492e-206 646.0
REGS3_k127_3789006_1 HlyD membrane-fusion protein of T1SS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004145 291.0
REGS3_k127_3789006_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000564 165.0
REGS3_k127_3789006_3 major facilitator superfamily K03446 - - 0.0000000000000000000000000006644 118.0
REGS3_k127_3789090_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 521.0
REGS3_k127_3789090_1 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 414.0
REGS3_k127_3789090_2 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000002165 254.0
REGS3_k127_3789090_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000004969 84.0
REGS3_k127_3820506_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 424.0
REGS3_k127_3820506_1 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 412.0
REGS3_k127_3820506_2 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000007803 228.0
REGS3_k127_3820506_3 protein conserved in bacteria K09796 - - 0.000000000000000000000000000008269 134.0
REGS3_k127_3820506_4 - - - - 0.0000000001797 64.0
REGS3_k127_3823460_0 ABC transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 604.0
REGS3_k127_3823460_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 547.0
REGS3_k127_3823460_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 357.0
REGS3_k127_3823460_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 305.0
REGS3_k127_3823460_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000004285 224.0
REGS3_k127_3823460_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000546 231.0
REGS3_k127_3823460_6 OmpA family K03286 - - 0.00000008511 62.0
REGS3_k127_3842170_0 Major facilitator Superfamily - - - 1.165e-268 838.0
REGS3_k127_3842170_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 405.0
REGS3_k127_3842170_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 391.0
REGS3_k127_3842170_3 NAD-dependent epimerase dehydratase K18981 - 1.1.1.203 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 303.0
REGS3_k127_3842170_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 293.0
REGS3_k127_3842170_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001877 255.0
REGS3_k127_3842170_6 Peptidase family M20/M25/M40 K13049 - - 0.0000000000000000000002902 97.0
REGS3_k127_3857775_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 335.0
REGS3_k127_3857775_1 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 302.0
REGS3_k127_3857775_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004267 240.0
REGS3_k127_3857775_3 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000005842 158.0
REGS3_k127_3857775_4 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000002319 97.0
REGS3_k127_386482_0 PFAM ABC transporter K02471 - - 5.751e-197 629.0
REGS3_k127_386482_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 401.0
REGS3_k127_386482_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000001056 241.0
REGS3_k127_386482_3 PFAM Sporulation domain protein - - - 0.0000008746 52.0
REGS3_k127_3867389_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 3.035e-218 681.0
REGS3_k127_3867389_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 480.0
REGS3_k127_3867389_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 485.0
REGS3_k127_3867389_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 358.0
REGS3_k127_3867389_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
REGS3_k127_3867389_5 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 340.0
REGS3_k127_3867389_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000007418 262.0
REGS3_k127_3867389_7 Sporulation related domain K03749 - - 0.0000000000000000000000000000002966 131.0
REGS3_k127_3867389_8 Psort location CytoplasmicMembrane, score K03558 - - 0.000000000000976 71.0
REGS3_k127_3932856_0 Transposase for IS481 element - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 453.0
REGS3_k127_3932856_1 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 386.0
REGS3_k127_3932856_2 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 291.0
REGS3_k127_3932856_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000001303 213.0
REGS3_k127_3932856_4 DNA ligase K01971 - 6.5.1.1 0.0000000000000000006596 87.0
REGS3_k127_3995553_0 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 339.0
REGS3_k127_3995553_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001778 259.0
REGS3_k127_3995553_2 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000000000002124 127.0
REGS3_k127_3995553_3 GDYXXLXY protein - - - 0.000000000000000007452 84.0
REGS3_k127_4014138_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 526.0
REGS3_k127_4014138_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 402.0
REGS3_k127_4014138_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002046 231.0
REGS3_k127_4014138_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000001598 94.0
REGS3_k127_4014138_4 Cold-shock DNA-binding domain protein K03704 - - 0.000000000333 60.0
REGS3_k127_403170_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1092.0
REGS3_k127_403170_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 7.02e-315 977.0
REGS3_k127_403170_2 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 334.0
REGS3_k127_403170_3 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003585 276.0
REGS3_k127_403170_4 Periplasmic protein thiol K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 253.0
REGS3_k127_403170_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000002025 217.0
REGS3_k127_403170_6 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000005302 161.0
REGS3_k127_403170_7 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000009163 142.0
REGS3_k127_403170_8 C-terminal AAA-associated domain K02049 - - 0.000000000267 62.0
REGS3_k127_4047557_0 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001158 261.0
REGS3_k127_4047557_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000205 267.0
REGS3_k127_4047557_2 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000964 214.0
REGS3_k127_4061077_0 PFAM Glycoside hydrolase 15-related - - - 1.348e-242 758.0
REGS3_k127_4061077_1 Catechol dioxygenase N terminus - - - 0.00000000000000000000000000000000000000000000000008951 180.0
REGS3_k127_4061077_2 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000002735 115.0
REGS3_k127_407730_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002713 285.0
REGS3_k127_407730_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000009251 109.0
REGS3_k127_4085889_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 502.0
REGS3_k127_4085889_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 456.0
REGS3_k127_4085889_10 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
REGS3_k127_4085889_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000002852 203.0
REGS3_k127_4085889_12 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000165 103.0
REGS3_k127_4085889_13 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.000000001141 70.0
REGS3_k127_4085889_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 447.0
REGS3_k127_4085889_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 342.0
REGS3_k127_4085889_4 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 315.0
REGS3_k127_4085889_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 313.0
REGS3_k127_4085889_6 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 299.0
REGS3_k127_4085889_7 SMP-30/Gluconolaconase/LRE-like region K13874 - 3.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000004204 269.0
REGS3_k127_4085889_8 Peptide methionine sulfoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000315 263.0
REGS3_k127_4085889_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002548 248.0
REGS3_k127_4114982_0 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 418.0
REGS3_k127_4114982_1 serine-type endopeptidase activity K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000001484 251.0
REGS3_k127_4114982_2 with different specificities (related to short-chain alcohol K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000003781 209.0
REGS3_k127_4114982_3 LysE type translocator - - - 0.00000000000000000000000000000000000007491 150.0
REGS3_k127_4126625_0 efflux transmembrane transporter activity - - - 8.869e-202 656.0
REGS3_k127_4126625_1 - - - - 0.0000000000000000000000000000000000000000000001141 169.0
REGS3_k127_4126625_2 DinB superfamily - - - 0.0000000000000000003396 95.0
REGS3_k127_415529_0 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000142 258.0
REGS3_k127_415529_1 Cupin - - - 0.000000000000000000000000000000000000000000000000000000001987 203.0
REGS3_k127_415529_2 Protein conserved in bacteria K09984 - - 0.000000000000000000000000000000000000000000000000001086 184.0
REGS3_k127_415529_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000002401 171.0
REGS3_k127_4176010_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 381.0
REGS3_k127_4176010_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
REGS3_k127_4176010_2 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000003022 124.0
REGS3_k127_4176010_3 - - - - 0.000003079 51.0
REGS3_k127_4182470_1 Universal stress protein family - - - 0.0000000000000000000000000000000000000000007169 162.0
REGS3_k127_4249091_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 550.0
REGS3_k127_4249091_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001573 252.0
REGS3_k127_4249091_2 Type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000008018 244.0
REGS3_k127_4249091_3 Transcriptional regulator K15539 - - 0.0000000000000000000000000000000005655 145.0
REGS3_k127_425477_0 Cysteine-rich domain - - - 5.726e-237 738.0
REGS3_k127_425477_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 499.0
REGS3_k127_425477_2 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007273 253.0
REGS3_k127_425477_3 Rubrerythrin - - - 0.000000000000000000000000000000000006654 136.0
REGS3_k127_425477_4 CNP1-like family - - - 0.00000000000000000000001069 115.0
REGS3_k127_429219_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 506.0
REGS3_k127_429219_1 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000000004289 209.0
REGS3_k127_429219_2 WD-40 repeat - - - 0.00000000000000000000000000000006844 143.0
REGS3_k127_4304389_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1405.0
REGS3_k127_4304389_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 9.525e-286 886.0
REGS3_k127_4304389_10 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 444.0
REGS3_k127_4304389_11 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 438.0
REGS3_k127_4304389_12 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 370.0
REGS3_k127_4304389_13 UTRA K02043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000067 244.0
REGS3_k127_4304389_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000000000001355 155.0
REGS3_k127_4304389_15 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000002654 137.0
REGS3_k127_4304389_16 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.000000000000009246 74.0
REGS3_k127_4304389_17 TPR repeat region K09159 - - 0.00000000000001106 76.0
REGS3_k127_4304389_2 MmgE/PrpD family K01720 - 4.2.1.79 4.306e-274 847.0
REGS3_k127_4304389_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 3.635e-260 807.0
REGS3_k127_4304389_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.449e-239 746.0
REGS3_k127_4304389_5 Belongs to the citrate synthase family K01659 - 2.3.3.5 7.339e-207 651.0
REGS3_k127_4304389_6 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.307e-203 643.0
REGS3_k127_4304389_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 554.0
REGS3_k127_4304389_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 531.0
REGS3_k127_4304389_9 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 463.0
REGS3_k127_4304862_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1028.0
REGS3_k127_4304862_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
REGS3_k127_4304862_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000001241 246.0
REGS3_k127_4304862_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000001067 239.0
REGS3_k127_4306077_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 580.0
REGS3_k127_4306077_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000006638 221.0
REGS3_k127_4306077_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000001865 186.0
REGS3_k127_4306077_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000001341 116.0
REGS3_k127_4315185_0 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000000001417 194.0
REGS3_k127_4315185_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000004127 186.0
REGS3_k127_4315185_2 META domain K03929 - - 0.0000000000001542 73.0
REGS3_k127_4315185_3 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00000001144 62.0
REGS3_k127_4328635_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 378.0
REGS3_k127_4328635_1 Malate/L-lactate dehydrogenase K00016,K00073 - 1.1.1.27,1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 366.0
REGS3_k127_4328635_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000003061 189.0
REGS3_k127_4335605_0 Thiolase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 520.0
REGS3_k127_4335605_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000001373 136.0
REGS3_k127_4335605_2 CoA binding domain K09181 - - 0.0000000000000000000000000004899 114.0
REGS3_k127_4341134_0 Peptidase family M41 K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 552.0
REGS3_k127_4348155_0 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 497.0
REGS3_k127_4348155_1 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 425.0
REGS3_k127_4348155_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 392.0
REGS3_k127_4348155_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 359.0
REGS3_k127_4348155_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 292.0
REGS3_k127_4350440_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 5e-323 998.0
REGS3_k127_4350440_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.848e-249 778.0
REGS3_k127_4350440_2 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 447.0
REGS3_k127_4350440_3 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
REGS3_k127_4354641_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 479.0
REGS3_k127_4354641_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 461.0
REGS3_k127_4354641_10 YaeQ - - - 0.000000000000000000000000000000000000000001155 159.0
REGS3_k127_4354641_2 LysR substrate binding domain K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 398.0
REGS3_k127_4354641_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 384.0
REGS3_k127_4354641_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 382.0
REGS3_k127_4354641_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 340.0
REGS3_k127_4354641_6 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 319.0
REGS3_k127_4354641_7 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
REGS3_k127_4354641_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 306.0
REGS3_k127_4354641_9 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000001297 219.0
REGS3_k127_435549_0 PQQ enzyme repeat - - - 2.769e-288 893.0
REGS3_k127_435549_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 250.0
REGS3_k127_435549_2 Ankyrin repeats (3 copies) K06867,K21440 - - 0.0000000000000000000000000000000000000000000000007978 183.0
REGS3_k127_435549_3 LemA family K03744 - - 0.00000000000000000000000000000000007891 134.0
REGS3_k127_435549_4 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000001741 129.0
REGS3_k127_435549_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000004 84.0
REGS3_k127_4359722_0 Peptidase M50 K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 528.0
REGS3_k127_4359722_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 503.0
REGS3_k127_4359722_2 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 390.0
REGS3_k127_4359722_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000239 166.0
REGS3_k127_4359722_4 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000004251 122.0
REGS3_k127_4359722_5 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.00000000000000000000004519 115.0
REGS3_k127_4362721_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 417.0
REGS3_k127_4362721_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 324.0
REGS3_k127_4362721_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.00001304 49.0
REGS3_k127_4362721_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00001965 55.0
REGS3_k127_4363543_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 430.0
REGS3_k127_4363543_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
REGS3_k127_4363543_2 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000003399 149.0
REGS3_k127_4363543_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000002635 58.0
REGS3_k127_4363543_4 Putative zinc-finger - - - 0.000004035 51.0
REGS3_k127_4363543_5 Putative zinc-finger - - - 0.0000439 46.0
REGS3_k127_4366430_0 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 579.0
REGS3_k127_4366430_1 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
REGS3_k127_4366430_2 Prokaryotic N-terminal methylation motif - - - 0.000000000000000008923 83.0
REGS3_k127_4366430_3 SnoaL-like polyketide cyclase - - - 0.000000006133 63.0
REGS3_k127_4367496_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.269e-229 726.0
REGS3_k127_4367496_1 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 483.0
REGS3_k127_4367496_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 303.0
REGS3_k127_4367496_3 SpoIIAA-like - - - 0.000000000000000000000000000001973 127.0
REGS3_k127_4369038_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 6.986e-281 869.0
REGS3_k127_4369038_1 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 1.496e-257 810.0
REGS3_k127_4369038_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 455.0
REGS3_k127_4369038_11 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 423.0
REGS3_k127_4369038_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 396.0
REGS3_k127_4369038_13 6-phosphogluconate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 321.0
REGS3_k127_4369038_14 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 318.0
REGS3_k127_4369038_15 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002668 280.0
REGS3_k127_4369038_16 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000006247 263.0
REGS3_k127_4369038_17 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003651 247.0
REGS3_k127_4369038_18 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000000007975 220.0
REGS3_k127_4369038_19 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000002469 194.0
REGS3_k127_4369038_2 poly(R)-hydroxyalkanoic acid synthase K03821 - - 3.444e-256 803.0
REGS3_k127_4369038_20 transcriptional - - - 0.000000000000000000000000000000000000003095 150.0
REGS3_k127_4369038_21 Protein of unknown function (DUF1289) K06938 - - 0.000000000008074 72.0
REGS3_k127_4369038_22 Sugar (and other) transporter - - - 0.00000000007052 70.0
REGS3_k127_4369038_3 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 6.559e-243 764.0
REGS3_k127_4369038_4 homoserine dehydrogenase - - - 3.492e-218 684.0
REGS3_k127_4369038_5 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 9.441e-209 661.0
REGS3_k127_4369038_6 Belongs to the thiolase family K00626 - 2.3.1.9 1.287e-197 621.0
REGS3_k127_4369038_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 555.0
REGS3_k127_4369038_8 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
REGS3_k127_4369038_9 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 462.0
REGS3_k127_4372551_0 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 2.031e-217 675.0
REGS3_k127_4372551_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 343.0
REGS3_k127_4372551_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000000000004509 212.0
REGS3_k127_4372551_3 Universal stress protein - - - 0.00000000000000000000000000000000004567 141.0
REGS3_k127_4375580_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 383.0
REGS3_k127_4375580_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 325.0
REGS3_k127_4375580_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 308.0
REGS3_k127_4375580_3 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
REGS3_k127_4375580_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 308.0
REGS3_k127_4375580_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000002472 123.0
REGS3_k127_4380754_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 4.439e-218 686.0
REGS3_k127_4380754_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
REGS3_k127_4381206_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 588.0
REGS3_k127_4381206_1 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 318.0
REGS3_k127_4381206_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000057 150.0
REGS3_k127_4381206_3 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000003697 120.0
REGS3_k127_4381762_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.607e-277 864.0
REGS3_k127_4381762_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 363.0
REGS3_k127_4381762_2 hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000004267 240.0
REGS3_k127_4381762_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000006016 184.0
REGS3_k127_4381762_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000704 114.0
REGS3_k127_4385468_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 342.0
REGS3_k127_4385468_1 Glycosyltransferase like family - - - 0.00000000000000000000000000000000000000000000403 181.0
REGS3_k127_4385468_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000002506 141.0
REGS3_k127_4385468_3 Transposase DDE domain - - - 0.00000000006576 63.0
REGS3_k127_4385468_4 transposition K07497 - - 0.000000002025 60.0
REGS3_k127_4385468_5 InterPro IPR002559 - - - 0.000000003998 60.0
REGS3_k127_4385667_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1039.0
REGS3_k127_4385667_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.512e-267 831.0
REGS3_k127_4385667_10 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
REGS3_k127_4385667_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 307.0
REGS3_k127_4385667_12 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 304.0
REGS3_k127_4385667_13 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 295.0
REGS3_k127_4385667_14 MucB/RseB C-terminal domain K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 301.0
REGS3_k127_4385667_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003799 276.0
REGS3_k127_4385667_16 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007951 270.0
REGS3_k127_4385667_17 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005796 258.0
REGS3_k127_4385667_18 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 247.0
REGS3_k127_4385667_19 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000008239 216.0
REGS3_k127_4385667_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.71e-255 800.0
REGS3_k127_4385667_20 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000005948 153.0
REGS3_k127_4385667_21 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000001486 144.0
REGS3_k127_4385667_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000007293 122.0
REGS3_k127_4385667_23 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000000000001893 102.0
REGS3_k127_4385667_24 Domain of unknown function (DUF4845) - - - 0.000000000000000006565 88.0
REGS3_k127_4385667_25 Domain of unknown function (DUF4936) - - - 0.00000000000000005709 85.0
REGS3_k127_4385667_26 - K19168 - - 0.00000000001167 72.0
REGS3_k127_4385667_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.679e-206 651.0
REGS3_k127_4385667_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 604.0
REGS3_k127_4385667_5 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 460.0
REGS3_k127_4385667_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 402.0
REGS3_k127_4385667_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 375.0
REGS3_k127_4385667_8 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 367.0
REGS3_k127_4385667_9 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 326.0
REGS3_k127_4386230_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.019e-243 759.0
REGS3_k127_4386230_1 acyl-CoA dehydrogenase activity K09456 - - 2.696e-215 681.0
REGS3_k127_4386230_2 Short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 393.0
REGS3_k127_4393644_0 PFAM AMP-dependent synthetase and ligase - - - 2.243e-220 695.0
REGS3_k127_4393644_1 PFAM methyltransferase small - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 578.0
REGS3_k127_4393644_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 273.0
REGS3_k127_4393644_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000002194 188.0
REGS3_k127_4400065_0 Protein of unknown function - - - 7.468e-300 962.0
REGS3_k127_4400065_1 modulator of DNA gyrase K03568 - - 1.109e-244 761.0
REGS3_k127_4400065_10 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000005406 209.0
REGS3_k127_4400065_11 SnoaL-like domain - - - 0.0000000000000000000000000000000006751 135.0
REGS3_k127_4400065_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000882 134.0
REGS3_k127_4400065_13 Zinc-finger domain - - - 0.0000000000000000000001207 108.0
REGS3_k127_4400065_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 2.252e-218 691.0
REGS3_k127_4400065_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.548e-214 682.0
REGS3_k127_4400065_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 526.0
REGS3_k127_4400065_5 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 462.0
REGS3_k127_4400065_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 422.0
REGS3_k127_4400065_7 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 414.0
REGS3_k127_4400065_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 382.0
REGS3_k127_4400065_9 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 289.0
REGS3_k127_4404604_0 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 340.0
REGS3_k127_4404604_1 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006138 258.0
REGS3_k127_4404604_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000004458 207.0
REGS3_k127_4404604_3 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.000000000000000000000000000000002128 134.0
REGS3_k127_4404604_4 CsbD-like - - - 0.0000000000000000000000000000002156 126.0
REGS3_k127_4404604_5 Protein of unknown function (DUF3185) - - - 0.00000000000003796 75.0
REGS3_k127_4404604_6 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.00000000000004919 81.0
REGS3_k127_4404604_7 - - - - 0.000000000003932 70.0
REGS3_k127_4404604_8 - - - - 0.000002556 55.0
REGS3_k127_4410661_0 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 504.0
REGS3_k127_4410661_1 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000154 253.0
REGS3_k127_4410661_2 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000002599 192.0
REGS3_k127_4418344_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1079.0
REGS3_k127_4418344_1 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.00000000000000000000000000001448 124.0
REGS3_k127_4440126_0 FAD binding domain - - - 0.0 1101.0
REGS3_k127_4440126_1 Diguanylate cyclase - - - 6.785e-216 719.0
REGS3_k127_4440126_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000006689 185.0
REGS3_k127_4440126_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000002065 167.0
REGS3_k127_4440126_12 PFAM FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000008463 168.0
REGS3_k127_4440126_13 - - - - 0.00000000000000000000000000000000000001542 152.0
REGS3_k127_4440126_14 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000003888 134.0
REGS3_k127_4440126_15 Protein of unknown function (DUF805) - - - 0.000000000000000000000000001343 119.0
REGS3_k127_4440126_16 - - - - 0.00000000000000000000000897 105.0
REGS3_k127_4440126_17 - - - - 0.00000000001374 70.0
REGS3_k127_4440126_2 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 560.0
REGS3_k127_4440126_3 Multidrug ABC transporter ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 492.0
REGS3_k127_4440126_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 427.0
REGS3_k127_4440126_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 353.0
REGS3_k127_4440126_6 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002284 265.0
REGS3_k127_4440126_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006689 239.0
REGS3_k127_4440126_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000001773 222.0
REGS3_k127_4440126_9 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000003715 214.0
REGS3_k127_4442071_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1212.0
REGS3_k127_4442071_1 TonB dependent receptor - - - 2.994e-256 808.0
REGS3_k127_4442071_10 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 321.0
REGS3_k127_4442071_11 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 291.0
REGS3_k127_4442071_12 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002111 288.0
REGS3_k127_4442071_13 PFAM HupE UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
REGS3_k127_4442071_14 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000003772 223.0
REGS3_k127_4442071_15 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000000000000007704 218.0
REGS3_k127_4442071_16 NikR C terminal nickel binding domain K07722 - - 0.00000000000000000000000000000000000000000000000001354 183.0
REGS3_k127_4442071_17 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000001617 182.0
REGS3_k127_4442071_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000989 176.0
REGS3_k127_4442071_19 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000003668 143.0
REGS3_k127_4442071_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 6.814e-227 707.0
REGS3_k127_4442071_20 HupE / UreJ protein - - - 0.0000000000000000003358 97.0
REGS3_k127_4442071_21 - - - - 0.0000000000000007673 84.0
REGS3_k127_4442071_3 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 576.0
REGS3_k127_4442071_4 Branched-chain amino acid transport system / permease component K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 533.0
REGS3_k127_4442071_5 NADH:flavin oxidoreductase / NADH oxidase family K00354,K09461 - 1.14.13.40,1.6.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 520.0
REGS3_k127_4442071_6 PFAM aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 485.0
REGS3_k127_4442071_7 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 411.0
REGS3_k127_4442071_8 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
REGS3_k127_4442071_9 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 381.0
REGS3_k127_4443961_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1611.0
REGS3_k127_4443961_1 Belongs to the radical SAM superfamily. PqqE family K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 554.0
REGS3_k127_4443961_10 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 289.0
REGS3_k127_4443961_11 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
REGS3_k127_4443961_12 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000178 218.0
REGS3_k127_4443961_13 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000001791 212.0
REGS3_k127_4443961_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000906 177.0
REGS3_k127_4443961_15 - - - - 0.000000000000000000000000000000000000000006366 159.0
REGS3_k127_4443961_16 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000007054 107.0
REGS3_k127_4443961_17 - - - - 0.00003748 50.0
REGS3_k127_4443961_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 454.0
REGS3_k127_4443961_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 436.0
REGS3_k127_4443961_4 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 415.0
REGS3_k127_4443961_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 367.0
REGS3_k127_4443961_6 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 366.0
REGS3_k127_4443961_7 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 355.0
REGS3_k127_4443961_8 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 337.0
REGS3_k127_4443961_9 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 329.0
REGS3_k127_4445566_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 523.0
REGS3_k127_4445566_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 444.0
REGS3_k127_4445566_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
REGS3_k127_4445566_3 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003941 259.0
REGS3_k127_4445566_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000001269 201.0
REGS3_k127_4445566_5 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000003644 147.0
REGS3_k127_4445566_6 NnrU protein - - - 0.0000000000000000000000000000000000002286 153.0
REGS3_k127_4445566_7 Domain of unknown function (DUF4124) - - - 0.00000000002784 75.0
REGS3_k127_4445566_8 - - - - 0.000002494 52.0
REGS3_k127_4454429_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 485.0
REGS3_k127_4454429_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 379.0
REGS3_k127_4454429_2 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000003244 174.0
REGS3_k127_4454429_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000002829 149.0
REGS3_k127_4457548_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1112.0
REGS3_k127_4457548_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1076.0
REGS3_k127_4457548_10 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 442.0
REGS3_k127_4457548_11 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 433.0
REGS3_k127_4457548_12 RNA cap guanine-N2 methyltransferase K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 380.0
REGS3_k127_4457548_13 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
REGS3_k127_4457548_14 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 344.0
REGS3_k127_4457548_15 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 324.0
REGS3_k127_4457548_16 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 287.0
REGS3_k127_4457548_17 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
REGS3_k127_4457548_18 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002235 266.0
REGS3_k127_4457548_19 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000676 235.0
REGS3_k127_4457548_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1013.0
REGS3_k127_4457548_20 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000008472 215.0
REGS3_k127_4457548_21 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000001455 240.0
REGS3_k127_4457548_22 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000005147 171.0
REGS3_k127_4457548_3 breast cancer carboxy-terminal domain K01972 - 6.5.1.2 3.007e-284 897.0
REGS3_k127_4457548_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 6.962e-276 855.0
REGS3_k127_4457548_5 DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity K02343 - 2.7.7.7 1.359e-203 647.0
REGS3_k127_4457548_6 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 579.0
REGS3_k127_4457548_7 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 568.0
REGS3_k127_4457548_8 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 484.0
REGS3_k127_4457548_9 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 462.0
REGS3_k127_4466664_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1346.0
REGS3_k127_4466664_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.401e-305 943.0
REGS3_k127_4466664_10 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 317.0
REGS3_k127_4466664_11 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000004132 264.0
REGS3_k127_4466664_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000002229 218.0
REGS3_k127_4466664_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000001158 163.0
REGS3_k127_4466664_14 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000002325 140.0
REGS3_k127_4466664_15 Pfam:DUF1049 K08992 - - 0.000000000000000000989 89.0
REGS3_k127_4466664_16 Uncharacterized lipoprotein K07286 - - 0.00000000000936 73.0
REGS3_k127_4466664_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.335e-263 826.0
REGS3_k127_4466664_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 585.0
REGS3_k127_4466664_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 567.0
REGS3_k127_4466664_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 552.0
REGS3_k127_4466664_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 482.0
REGS3_k127_4466664_7 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 443.0
REGS3_k127_4466664_8 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 364.0
REGS3_k127_4466664_9 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 331.0
REGS3_k127_4480298_0 enoyl-CoA hydratase K15513 - 4.1.2.44 9.678e-257 801.0
REGS3_k127_4480298_1 Shikimate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 318.0
REGS3_k127_4480298_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000006692 256.0
REGS3_k127_4480298_3 Flavodoxin - - - 0.0000000000000000000000000000000000001642 147.0
REGS3_k127_4480298_4 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000001908 70.0
REGS3_k127_4493480_0 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 468.0
REGS3_k127_4493480_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 452.0
REGS3_k127_4493480_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 454.0
REGS3_k127_4493480_3 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008215 268.0
REGS3_k127_4493480_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001371 251.0
REGS3_k127_4493480_5 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001868 236.0
REGS3_k127_4493480_6 PFAM glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000002276 142.0
REGS3_k127_4493480_7 Protein of unknown function (DUF3309) - - - 0.00000000000000000001214 92.0
REGS3_k127_4493480_8 Periplasmic or secreted lipoprotein - - - 0.0000000588 56.0
REGS3_k127_4503437_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.785e-240 752.0
REGS3_k127_4503437_1 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 501.0
REGS3_k127_4512862_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.043e-243 773.0
REGS3_k127_4512862_1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000003101 229.0
REGS3_k127_4512862_2 cyclic nucleotide binding K01420 - - 0.00000000000000000000000000000000000000000000000000008844 198.0
REGS3_k127_4512862_3 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000003469 131.0
REGS3_k127_4512862_4 Sulphur oxidation protein SoxZ - - - 0.000000000000000000000000008256 119.0
REGS3_k127_4512862_5 - - - - 0.0000000001453 70.0
REGS3_k127_4518086_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 1.328e-303 942.0
REGS3_k127_4518086_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.548e-263 829.0
REGS3_k127_4518086_10 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 302.0
REGS3_k127_4518086_11 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002521 249.0
REGS3_k127_4518086_12 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000005512 161.0
REGS3_k127_4518086_13 PFAM MgtC SapB transporter - - - 0.0000000000000000000000000000000000000000007169 162.0
REGS3_k127_4518086_14 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000009653 156.0
REGS3_k127_4518086_15 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000001707 119.0
REGS3_k127_4518086_16 Heavy-metal-associated domain K07213 - - 0.000000000000000001707 87.0
REGS3_k127_4518086_17 Phasin protein - - - 0.00000000000000002149 89.0
REGS3_k127_4518086_18 - - - - 0.0000000000007321 74.0
REGS3_k127_4518086_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 6.758e-231 725.0
REGS3_k127_4518086_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.501e-227 721.0
REGS3_k127_4518086_4 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 608.0
REGS3_k127_4518086_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 593.0
REGS3_k127_4518086_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 415.0
REGS3_k127_4518086_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 378.0
REGS3_k127_4518086_8 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 349.0
REGS3_k127_4518086_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 341.0
REGS3_k127_4520052_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 524.0
REGS3_k127_4520052_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
REGS3_k127_4520052_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000004164 239.0
REGS3_k127_4520052_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000002148 238.0
REGS3_k127_4520052_4 CHASE3 domain K03406 - - 0.000000000000002292 82.0
REGS3_k127_4552136_0 type II and III secretion system protein K02453,K12282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 589.0
REGS3_k127_4552136_1 AAA domain K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 369.0
REGS3_k127_4552136_2 carbon utilization K12280 - - 0.0000000000000000000000000000000000000001827 163.0
REGS3_k127_4552136_3 PFAM Fimbrial assembly family protein - - - 0.000000000000000000000000000000009254 136.0
REGS3_k127_4552136_4 Tetratricopeptide repeat K12284 - - 0.00000000000005139 84.0
REGS3_k127_4552136_5 - K12281 - - 0.0000005887 60.0
REGS3_k127_4579803_0 ABC transporter substrate-binding protein K02027 - - 3.358e-238 744.0
REGS3_k127_4579803_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 2.326e-210 657.0
REGS3_k127_4579803_10 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 287.0
REGS3_k127_4579803_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002414 283.0
REGS3_k127_4579803_12 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000009486 253.0
REGS3_k127_4579803_13 O-methyltransferase - - - 0.000000000000000000000000000000000000000000003116 174.0
REGS3_k127_4579803_14 Protein of unknown function (DUF3299) K09950 - - 0.00000000000000000000000000000000000000001064 163.0
REGS3_k127_4579803_2 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 494.0
REGS3_k127_4579803_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 474.0
REGS3_k127_4579803_4 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 459.0
REGS3_k127_4579803_5 ABC-type sugar transport system, permease component K02026,K17323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 434.0
REGS3_k127_4579803_6 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 427.0
REGS3_k127_4579803_7 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 417.0
REGS3_k127_4579803_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 386.0
REGS3_k127_4579803_9 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 346.0
REGS3_k127_4627156_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 571.0
REGS3_k127_4627156_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 338.0
REGS3_k127_4627156_2 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 311.0
REGS3_k127_4627156_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000001806 228.0
REGS3_k127_4627156_4 oxidation-reduction process - - - 0.00000000000000000000000000000000000000006201 157.0
REGS3_k127_4710386_0 4Fe-4S dicluster domain - - - 0.0 1299.0
REGS3_k127_4710386_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 607.0
REGS3_k127_4710386_2 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 576.0
REGS3_k127_4710386_3 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 445.0
REGS3_k127_4710386_4 Belongs to the SUA5 family K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 363.0
REGS3_k127_4710386_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000004102 219.0
REGS3_k127_4710386_6 Phosphate-starvation-inducible E K13256 - - 0.000000000000000000000000000000000000000000001453 169.0
REGS3_k127_4710386_7 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000001804 61.0
REGS3_k127_4720785_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.808e-225 708.0
REGS3_k127_4720785_1 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 407.0
REGS3_k127_4720785_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 411.0
REGS3_k127_4720785_3 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 301.0
REGS3_k127_4720785_4 CoA-transferase family III K18289 - 2.8.3.22 0.00000000000000000000000000001539 118.0
REGS3_k127_4734842_0 AAA domain - - - 0.0 1217.0
REGS3_k127_4734842_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1137.0
REGS3_k127_4734842_2 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001165 260.0
REGS3_k127_4734842_3 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000001638 148.0
REGS3_k127_4734842_4 - - - - 0.000000000000000000512 90.0
REGS3_k127_4744230_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00256 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 597.0
REGS3_k127_4744230_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 553.0
REGS3_k127_4744230_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000004014 210.0
REGS3_k127_4744230_3 Short chain fatty acid transporter K02106 - - 0.0000000000000000000004531 98.0
REGS3_k127_4754756_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 3.203e-261 810.0
REGS3_k127_4754756_1 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 560.0
REGS3_k127_4754756_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000381 84.0
REGS3_k127_4949603_0 Catalyzes the hydrolysis of short-chain aliphatic amides to their K01426,K01455 - 3.5.1.4,3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 452.0
REGS3_k127_4949603_1 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 399.0
REGS3_k127_4973896_0 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 552.0
REGS3_k127_4973896_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 410.0
REGS3_k127_4973896_2 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 402.0
REGS3_k127_4973896_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 401.0
REGS3_k127_4973896_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 348.0
REGS3_k127_4973896_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000009425 155.0
REGS3_k127_4973896_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000257 135.0
REGS3_k127_5063272_0 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
REGS3_k127_5063272_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 340.0
REGS3_k127_5063272_2 Binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007381 262.0
REGS3_k127_5063272_3 deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
REGS3_k127_5063272_4 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000008375 214.0
REGS3_k127_5065820_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 587.0
REGS3_k127_5065820_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000001573 138.0
REGS3_k127_5093702_0 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 2.807e-246 775.0
REGS3_k127_5093702_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 547.0
REGS3_k127_5093702_2 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 539.0
REGS3_k127_5093702_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 472.0
REGS3_k127_5093702_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 389.0
REGS3_k127_5093702_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 312.0
REGS3_k127_5093702_6 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000002942 142.0
REGS3_k127_5093702_7 PFAM 17 kDa surface antigen - - - 0.0000000000000000000000000003129 132.0
REGS3_k127_5093702_8 MarR family - - - 0.0000000000000000000000008817 109.0
REGS3_k127_5121427_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 1.337e-211 663.0
REGS3_k127_5121427_1 - - - - 0.00000000001036 70.0
REGS3_k127_5121427_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.0000000003031 60.0
REGS3_k127_5121427_3 PFAM 17 kDa surface antigen - - - 0.0000008285 58.0
REGS3_k127_5159405_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006139 272.0
REGS3_k127_5159405_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000002463 137.0
REGS3_k127_5159405_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000003397 122.0
REGS3_k127_5159405_3 Protein of unknown function (DUF3309) - - - 0.000000000000000004379 88.0
REGS3_k127_5159405_4 Uncharacterized lipoprotein K07286 - - 0.0000000002834 69.0
REGS3_k127_5165153_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 390.0
REGS3_k127_5165153_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 382.0
REGS3_k127_5165153_2 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000008335 234.0
REGS3_k127_5165153_3 OmpA family K03640 - - 0.0000000000000000000000000000000002853 142.0
REGS3_k127_5165153_4 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000001854 130.0
REGS3_k127_5165153_5 TolA C-terminal K03646 - - 0.000000000000000000000000008931 123.0
REGS3_k127_5165153_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000001073 114.0
REGS3_k127_5170004_0 Cell wall hydrolyses involved in spore germination - - - 0.0000000000000000000000004762 112.0
REGS3_k127_5170004_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000001462 104.0
REGS3_k127_5170004_2 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000001872 88.0
REGS3_k127_5170004_3 PFAM SpoVT AbrB K07172 - - 0.000000001255 62.0
REGS3_k127_5205449_0 DEAD DEAH box helicase K03724 - - 0.0 1024.0
REGS3_k127_523276_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 388.0
REGS3_k127_523276_1 - - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
REGS3_k127_523276_2 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
REGS3_k127_523276_3 oxidation-reduction process - - - 0.0000000000000000000000000000002089 128.0
REGS3_k127_523276_4 - - - - 0.00000000000000000003235 95.0
REGS3_k127_5233046_0 PFAM Carbon starvation protein CstA K06200 - - 0.0 1017.0
REGS3_k127_5233046_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322,K01354 - 3.4.21.26,3.4.21.83 1.13e-235 749.0
REGS3_k127_5233046_11 Protein of unknown function (DUF3460) - - - 0.000000000001703 69.0
REGS3_k127_5233046_12 Selenoprotein, putative - - - 0.0000001181 65.0
REGS3_k127_5233046_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.894e-211 661.0
REGS3_k127_5233046_3 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 445.0
REGS3_k127_5233046_4 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 403.0
REGS3_k127_5233046_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 327.0
REGS3_k127_5233046_6 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001361 284.0
REGS3_k127_5233046_7 luciferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003488 264.0
REGS3_k127_5233046_8 G T U mismatch-specific DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000001255 183.0
REGS3_k127_5233046_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000005831 122.0
REGS3_k127_5243477_0 abc transporter K06020 - 3.6.3.25 4.224e-276 854.0
REGS3_k127_5243477_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 375.0
REGS3_k127_5243477_2 - - - - 0.0000000000000000000000000000000000000000001309 170.0
REGS3_k127_5243477_3 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000008536 153.0
REGS3_k127_5245277_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 7.715e-254 789.0
REGS3_k127_5245277_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 2.328e-223 700.0
REGS3_k127_5245277_10 Type II secretory pathway, pseudopilin - - - 0.000000000000000000000000000000000000000000000006518 178.0
REGS3_k127_5245277_11 prepilin-type N-terminal cleavage methylation K02456 - - 0.0000000000000000000000000000000000000000000000648 173.0
REGS3_k127_5245277_12 NIPSNAP - - - 0.00000000000000000000000000000000000000000009225 162.0
REGS3_k127_5245277_13 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000002585 92.0
REGS3_k127_5245277_14 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.0000000000000000001889 96.0
REGS3_k127_5245277_15 PFAM membrane protein of K08972 - - 0.00000000000007598 78.0
REGS3_k127_5245277_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 558.0
REGS3_k127_5245277_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 515.0
REGS3_k127_5245277_4 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 327.0
REGS3_k127_5245277_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
REGS3_k127_5245277_6 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
REGS3_k127_5245277_7 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000000000000191 209.0
REGS3_k127_5245277_8 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000006815 188.0
REGS3_k127_5245277_9 Aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000001318 187.0
REGS3_k127_5250333_0 transferase activity, transferring glycosyl groups K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 597.0
REGS3_k127_5250333_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 559.0
REGS3_k127_5257648_0 cation transport ATPase K01533 - 3.6.3.4 3.684e-232 739.0
REGS3_k127_5257648_1 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000003057 80.0
REGS3_k127_5272954_0 Amidohydrolase family - - - 9.361e-246 765.0
REGS3_k127_5272954_1 nitrite reductase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 557.0
REGS3_k127_5272954_2 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000004402 171.0
REGS3_k127_5273967_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
REGS3_k127_5273967_1 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000001147 136.0
REGS3_k127_5273967_2 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000001303 118.0
REGS3_k127_5303069_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 3e-323 996.0
REGS3_k127_5303069_1 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 523.0
REGS3_k127_5303069_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 341.0
REGS3_k127_5303069_3 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005193 276.0
REGS3_k127_5303069_4 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009569 250.0
REGS3_k127_5303069_5 Protein of unknown function (DUF3096) - - - 0.00000000000009588 72.0
REGS3_k127_5304736_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 472.0
REGS3_k127_5304736_1 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 443.0
REGS3_k127_5304736_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000004443 119.0
REGS3_k127_5307745_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.761e-296 914.0
REGS3_k127_5307745_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.965e-222 694.0
REGS3_k127_530937_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 460.0
REGS3_k127_530937_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 428.0
REGS3_k127_530937_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 407.0
REGS3_k127_530937_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 286.0
REGS3_k127_530937_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003717 279.0
REGS3_k127_530937_5 - - - - 0.000000000000000000000000000000000000000000000001234 188.0
REGS3_k127_530937_6 Permease MlaE - - - 0.00000000000000000000000000000000000000001889 158.0
REGS3_k127_530937_7 - - - - 0.0000000000009393 77.0
REGS3_k127_530937_8 ABC transporter K02028 - 3.6.3.21 0.00004989 52.0
REGS3_k127_5326134_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.801e-267 831.0
REGS3_k127_5326134_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 541.0
REGS3_k127_5326134_2 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 441.0
REGS3_k127_5326134_3 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 369.0
REGS3_k127_5326134_4 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 303.0
REGS3_k127_5326134_5 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005519 257.0
REGS3_k127_5326134_6 response regulator K02485 - - 0.00000000000000000000000000000000000000000000000000000000005651 209.0
REGS3_k127_5326134_7 Protein of unknown function (DUF541) - - - 0.000000000000000000000000131 115.0
REGS3_k127_5326134_8 GGDEF domain - - - 0.00000000000005019 76.0
REGS3_k127_5335794_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 334.0
REGS3_k127_5335794_1 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 322.0
REGS3_k127_5335794_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000002149 105.0
REGS3_k127_5335794_3 - - - - 0.000001407 53.0
REGS3_k127_5359063_0 ABC transporter K02056 - 3.6.3.17 8.153e-203 647.0
REGS3_k127_5359063_1 Amidase K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 618.0
REGS3_k127_5359063_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 344.0
REGS3_k127_5359063_3 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 317.0
REGS3_k127_5359063_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005466 270.0
REGS3_k127_5359063_5 Catalyzes the hydrolysis of short-chain aliphatic amides to their K01426,K01455 - 3.5.1.4,3.5.1.49 0.00004851 46.0
REGS3_k127_5385134_0 transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000471 305.0
REGS3_k127_5385134_1 - K01992 - - 0.0000000000000000000000000000000002274 141.0
REGS3_k127_5385134_2 Domain of unknown function (DUF4340) - - - 0.0000008372 56.0
REGS3_k127_5390112_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.145e-233 736.0
REGS3_k127_5390112_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 577.0
REGS3_k127_5390112_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 482.0
REGS3_k127_5390112_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 457.0
REGS3_k127_5390112_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 341.0
REGS3_k127_5390112_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 298.0
REGS3_k127_5390112_6 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
REGS3_k127_5390112_7 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0000000000000000000000000000000000000000000000000000006877 193.0
REGS3_k127_5390112_8 - - - - 0.000000000000000000000000000004653 122.0
REGS3_k127_5392049_0 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 1.761e-228 718.0
REGS3_k127_5392049_1 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 3.574e-200 640.0
REGS3_k127_5392049_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 354.0
REGS3_k127_5392049_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 300.0
REGS3_k127_5392049_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000004188 139.0
REGS3_k127_5392049_5 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000002054 123.0
REGS3_k127_5392049_6 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000000000000000008197 85.0
REGS3_k127_5392049_7 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000002341 83.0
REGS3_k127_5410018_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 327.0
REGS3_k127_5410018_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000002144 194.0
REGS3_k127_5410018_2 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000002562 175.0
REGS3_k127_54124_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1512.0
REGS3_k127_54124_1 Belongs to the UPF0061 (SELO) family - - - 2.211e-256 799.0
REGS3_k127_54124_2 Putative Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 601.0
REGS3_k127_54124_3 Alanine-glyoxylate amino-transferase K00375,K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 557.0
REGS3_k127_54124_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 434.0
REGS3_k127_54124_5 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 330.0
REGS3_k127_54124_6 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
REGS3_k127_54124_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000003786 206.0
REGS3_k127_54124_8 - - - - 0.00000006877 57.0
REGS3_k127_54124_9 L COG3666 Transposase and inactivated derivatives - - - 0.000004927 49.0
REGS3_k127_5432853_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 536.0
REGS3_k127_5432853_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 481.0
REGS3_k127_5432853_2 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 427.0
REGS3_k127_5432853_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 323.0
REGS3_k127_5432853_4 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000001715 207.0
REGS3_k127_5432853_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000002608 133.0
REGS3_k127_5432853_6 AAA domain (dynein-related subfamily) - - - 0.0000000000000000002298 88.0
REGS3_k127_5456271_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2527.0
REGS3_k127_5456271_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1347.0
REGS3_k127_5456271_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 3.639e-196 622.0
REGS3_k127_5456271_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 539.0
REGS3_k127_5456271_4 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000000003082 126.0
REGS3_k127_5456271_5 pyrroloquinoline quinone binding - - - 0.000000000000000496 78.0
REGS3_k127_5467918_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1192.0
REGS3_k127_5467918_1 Atp-dependent helicase K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001504 283.0
REGS3_k127_5467918_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000001082 153.0
REGS3_k127_5479747_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1600.0
REGS3_k127_5479747_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.865e-257 805.0
REGS3_k127_5479747_10 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000003702 162.0
REGS3_k127_5479747_2 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.36e-246 771.0
REGS3_k127_5479747_3 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.886e-243 758.0
REGS3_k127_5479747_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.255e-226 724.0
REGS3_k127_5479747_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 551.0
REGS3_k127_5479747_6 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 550.0
REGS3_k127_5479747_7 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000004377 180.0
REGS3_k127_5479747_8 KR domain - - - 0.0000000000000000000000000000000000000000000005896 170.0
REGS3_k127_5479747_9 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000001277 171.0
REGS3_k127_5480756_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 584.0
REGS3_k127_5480756_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 344.0
REGS3_k127_5480756_2 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 310.0
REGS3_k127_5480756_3 Serine hydrolase (FSH1) K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 294.0
REGS3_k127_5480756_4 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000007028 208.0
REGS3_k127_5480756_5 - - - - 0.0000000000000000000000000000000000000000003724 179.0
REGS3_k127_5480756_6 CBS domain - - - 0.00000000000000000000000000000000000000116 152.0
REGS3_k127_5486487_0 Acetokinase family K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 359.0
REGS3_k127_5497048_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 390.0
REGS3_k127_5497048_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
REGS3_k127_5497048_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000001075 204.0
REGS3_k127_5497048_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000002038 59.0
REGS3_k127_5501929_0 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 524.0
REGS3_k127_5501929_1 protocatechuate 3,4-dioxygenase, beta subunit' K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 325.0
REGS3_k127_5501929_2 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000001193 234.0
REGS3_k127_5501929_3 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000002488 205.0
REGS3_k127_5510509_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 524.0
REGS3_k127_5510509_1 Aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 422.0
REGS3_k127_5510509_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006796 269.0
REGS3_k127_5510509_3 Protein of unknown function (DUF493) K09158 - - 0.000000000000000000000000000009496 120.0
REGS3_k127_5510509_4 Redoxin domain protein - - - 0.0000000000000000000000001955 107.0
REGS3_k127_5510926_0 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 349.0
REGS3_k127_5510926_1 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000001191 164.0
REGS3_k127_5510926_2 protein conserved in bacteria - - - 0.0000000000000000000001546 103.0
REGS3_k127_5510926_3 pyrroloquinoline quinone binding - - - 0.000000000000000000001633 98.0
REGS3_k127_5510926_4 Domain of unknown function (DUF5117) - - - 0.00000003555 61.0
REGS3_k127_5510926_5 Cytochrome c K00406 - - 0.00000005346 60.0
REGS3_k127_5522051_0 ATP cone domain K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 541.0
REGS3_k127_5522051_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000003458 198.0
REGS3_k127_5530679_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 584.0
REGS3_k127_5530679_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003317 258.0
REGS3_k127_5530679_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000002181 177.0
REGS3_k127_5530679_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000348 156.0
REGS3_k127_5547094_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.008e-288 910.0
REGS3_k127_5547094_1 Universal stress protein - - - 0.000000000000000000000000000009809 130.0
REGS3_k127_5547094_2 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000003374 79.0
REGS3_k127_5547094_3 Universal stress protein family - - - 0.0000000000008157 79.0
REGS3_k127_5559089_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 606.0
REGS3_k127_5559089_1 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 488.0
REGS3_k127_5559089_2 Anhydro-N-acetylmuramic acid kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 443.0
REGS3_k127_5559089_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 314.0
REGS3_k127_5559089_4 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000003527 209.0
REGS3_k127_5559089_5 - - - - 0.0000000000000000000000000000000000000000000000000005398 197.0
REGS3_k127_5559089_6 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000001691 179.0
REGS3_k127_5575935_0 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 343.0
REGS3_k127_5575935_1 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 304.0
REGS3_k127_5575935_2 PFAM Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
REGS3_k127_5575935_3 Beta-lactamase K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000005617 183.0
REGS3_k127_5575935_4 with different specificities (related to short-chain alcohol K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000009265 163.0
REGS3_k127_5575935_5 Uncharacterized ACR, COG1678 K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000001134 106.0
REGS3_k127_5583027_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1029.0
REGS3_k127_5583027_1 Glycine zipper 2TM domain - - - 0.000000000000000000000000004236 116.0
REGS3_k127_5606890_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1182.0
REGS3_k127_5606890_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.933e-319 989.0
REGS3_k127_5606890_10 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
REGS3_k127_5606890_11 Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate K01003 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 388.0
REGS3_k127_5606890_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 388.0
REGS3_k127_5606890_13 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 385.0
REGS3_k127_5606890_14 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 347.0
REGS3_k127_5606890_15 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 311.0
REGS3_k127_5606890_16 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002986 287.0
REGS3_k127_5606890_17 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000001758 246.0
REGS3_k127_5606890_18 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000003639 168.0
REGS3_k127_5606890_19 Cold shock protein K03704 - - 0.0000000000000000000000000000000001137 134.0
REGS3_k127_5606890_2 TIGRFAM malate synthase A K01638 - 2.3.3.9 4.889e-259 807.0
REGS3_k127_5606890_20 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000007676 101.0
REGS3_k127_5606890_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 2.21e-227 709.0
REGS3_k127_5606890_4 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 3.563e-225 702.0
REGS3_k127_5606890_5 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 542.0
REGS3_k127_5606890_6 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 483.0
REGS3_k127_5606890_7 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 479.0
REGS3_k127_5606890_8 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 472.0
REGS3_k127_5606890_9 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 433.0
REGS3_k127_5645267_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1193.0
REGS3_k127_5645267_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1169.0
REGS3_k127_5645267_10 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 2.552e-206 650.0
REGS3_k127_5645267_11 cystathionine K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 527.0
REGS3_k127_5645267_12 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 507.0
REGS3_k127_5645267_13 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 503.0
REGS3_k127_5645267_14 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 499.0
REGS3_k127_5645267_15 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 412.0
REGS3_k127_5645267_16 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 397.0
REGS3_k127_5645267_17 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 394.0
REGS3_k127_5645267_18 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 388.0
REGS3_k127_5645267_19 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 370.0
REGS3_k127_5645267_2 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1153.0
REGS3_k127_5645267_20 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 342.0
REGS3_k127_5645267_21 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 346.0
REGS3_k127_5645267_22 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 333.0
REGS3_k127_5645267_23 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 331.0
REGS3_k127_5645267_24 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 327.0
REGS3_k127_5645267_25 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 316.0
REGS3_k127_5645267_26 (FHA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 316.0
REGS3_k127_5645267_27 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 319.0
REGS3_k127_5645267_28 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 303.0
REGS3_k127_5645267_29 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 291.0
REGS3_k127_5645267_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1127.0
REGS3_k127_5645267_30 Nitrile hydratase, alpha chain K01721,K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
REGS3_k127_5645267_31 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 291.0
REGS3_k127_5645267_32 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000728 295.0
REGS3_k127_5645267_33 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 246.0
REGS3_k127_5645267_34 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000005181 240.0
REGS3_k127_5645267_35 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001478 239.0
REGS3_k127_5645267_36 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000001817 217.0
REGS3_k127_5645267_37 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000002386 203.0
REGS3_k127_5645267_38 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000003999 205.0
REGS3_k127_5645267_39 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000007751 188.0
REGS3_k127_5645267_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 1.358e-304 950.0
REGS3_k127_5645267_40 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000002747 195.0
REGS3_k127_5645267_41 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000001021 177.0
REGS3_k127_5645267_42 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000001125 164.0
REGS3_k127_5645267_43 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000005754 159.0
REGS3_k127_5645267_44 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000000004182 165.0
REGS3_k127_5645267_45 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000000000000000000008932 146.0
REGS3_k127_5645267_46 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000001557 124.0
REGS3_k127_5645267_47 FeoA K04758 - - 0.00000000000000001838 85.0
REGS3_k127_5645267_48 Glycosyltransferase Family 4 - - - 0.0008996 43.0
REGS3_k127_5645267_5 Ferrous iron transport protein B C terminus K04759 - - 2.665e-292 908.0
REGS3_k127_5645267_6 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 8.286e-248 769.0
REGS3_k127_5645267_7 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.936e-239 760.0
REGS3_k127_5645267_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 2.502e-229 721.0
REGS3_k127_5645267_9 argininosuccinate lyase K01755 - 4.3.2.1 7.688e-227 711.0
REGS3_k127_5646878_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 9.717e-210 662.0
REGS3_k127_5646878_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 7.174e-203 637.0
REGS3_k127_5646878_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000004869 175.0
REGS3_k127_5646878_3 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000000000001094 154.0
REGS3_k127_5647592_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 559.0
REGS3_k127_5647592_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 466.0
REGS3_k127_5647592_2 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 352.0
REGS3_k127_5647592_3 NIPSNAP - - - 0.00000000000000000000000000000000000000000001337 163.0
REGS3_k127_5647592_4 - - - - 0.000000000000005419 83.0
REGS3_k127_5682552_0 - - - - 0.0000000000000000000000000000328 128.0
REGS3_k127_5682552_1 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000003817 69.0
REGS3_k127_5682552_2 DsrE/DsrF-like family - - - 0.00000001602 57.0
REGS3_k127_5690715_0 PQQ enzyme repeat - - - 0.0 1088.0
REGS3_k127_5690715_1 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 543.0
REGS3_k127_5713424_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 336.0
REGS3_k127_5713424_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 329.0
REGS3_k127_5713424_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000004293 107.0
REGS3_k127_5733414_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 3.014e-204 647.0
REGS3_k127_5733414_1 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 299.0
REGS3_k127_5733414_2 Scaffold protein Nfu/NifU N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002446 248.0
REGS3_k127_5733414_3 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000849 224.0
REGS3_k127_5759207_0 aldo keto reductase K00011 - 1.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 422.0
REGS3_k127_5759207_1 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 321.0
REGS3_k127_5759207_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001201 261.0
REGS3_k127_5759207_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000228 180.0
REGS3_k127_5759207_4 Dodecin K09165 - - 0.00000000000000000000001812 102.0
REGS3_k127_5759207_5 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000006966 85.0
REGS3_k127_5766690_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 8.777e-316 985.0
REGS3_k127_5766690_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.44e-281 876.0
REGS3_k127_5766690_10 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.595e-214 669.0
REGS3_k127_5766690_11 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.643e-211 665.0
REGS3_k127_5766690_12 Belongs to the GARS family K01945 - 6.3.4.13 1.713e-209 658.0
REGS3_k127_5766690_13 Aminotransferase K01845 - 5.4.3.8 3.361e-204 642.0
REGS3_k127_5766690_14 Belongs to the peptidase M24B family K01262 - 3.4.11.9 1.319e-202 639.0
REGS3_k127_5766690_15 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.458e-201 649.0
REGS3_k127_5766690_16 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 553.0
REGS3_k127_5766690_17 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 553.0
REGS3_k127_5766690_18 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 527.0
REGS3_k127_5766690_19 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 520.0
REGS3_k127_5766690_2 Transport of potassium into the cell K03549 - - 1.823e-279 871.0
REGS3_k127_5766690_20 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 520.0
REGS3_k127_5766690_21 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 507.0
REGS3_k127_5766690_22 Type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 501.0
REGS3_k127_5766690_23 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 502.0
REGS3_k127_5766690_24 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 489.0
REGS3_k127_5766690_25 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 488.0
REGS3_k127_5766690_26 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 441.0
REGS3_k127_5766690_27 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 426.0
REGS3_k127_5766690_28 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 424.0
REGS3_k127_5766690_29 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 417.0
REGS3_k127_5766690_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.602e-277 870.0
REGS3_k127_5766690_30 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 415.0
REGS3_k127_5766690_31 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 411.0
REGS3_k127_5766690_32 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 402.0
REGS3_k127_5766690_33 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 403.0
REGS3_k127_5766690_34 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 394.0
REGS3_k127_5766690_35 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 384.0
REGS3_k127_5766690_36 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 376.0
REGS3_k127_5766690_37 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 360.0
REGS3_k127_5766690_38 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
REGS3_k127_5766690_39 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 346.0
REGS3_k127_5766690_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 2.768e-271 838.0
REGS3_k127_5766690_40 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 336.0
REGS3_k127_5766690_41 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 333.0
REGS3_k127_5766690_42 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 325.0
REGS3_k127_5766690_43 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 312.0
REGS3_k127_5766690_44 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 303.0
REGS3_k127_5766690_45 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 301.0
REGS3_k127_5766690_46 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006651 268.0
REGS3_k127_5766690_47 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
REGS3_k127_5766690_48 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000001907 267.0
REGS3_k127_5766690_49 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008681 242.0
REGS3_k127_5766690_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.665e-240 758.0
REGS3_k127_5766690_50 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000003436 239.0
REGS3_k127_5766690_51 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000008509 237.0
REGS3_k127_5766690_52 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 240.0
REGS3_k127_5766690_53 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000161 232.0
REGS3_k127_5766690_54 nucleoside-diphosphate sugar epimerase - - - 0.000000000000000000000000000000000000000000000000000000000003556 215.0
REGS3_k127_5766690_55 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000001199 213.0
REGS3_k127_5766690_56 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000001149 205.0
REGS3_k127_5766690_57 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000000001885 201.0
REGS3_k127_5766690_58 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000003673 188.0
REGS3_k127_5766690_59 FR47-like protein - - - 0.0000000000000000000000000000000000000000008634 168.0
REGS3_k127_5766690_6 ribonuclease II K01147 - 3.1.13.1 1.146e-233 738.0
REGS3_k127_5766690_60 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000002259 170.0
REGS3_k127_5766690_61 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000001582 166.0
REGS3_k127_5766690_62 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000842 156.0
REGS3_k127_5766690_63 SapC - - - 0.00000000000000000000000000000000000002232 156.0
REGS3_k127_5766690_64 Tetratricopeptide repeat - - - 0.00000000000000000000000000000006671 127.0
REGS3_k127_5766690_65 PFAM cytochrome c, class I K08738 - - 0.000000000000000000000000000001313 124.0
REGS3_k127_5766690_66 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000000000001645 123.0
REGS3_k127_5766690_67 Belongs to the UPF0237 family K07166 - - 0.00000000000000000000000000005097 119.0
REGS3_k127_5766690_68 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000001183 115.0
REGS3_k127_5766690_69 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000001655 130.0
REGS3_k127_5766690_7 UPF0210 protein K09157 - - 4.415e-222 698.0
REGS3_k127_5766690_70 Bacterial SH3 domain - - - 0.0000000000000000005914 94.0
REGS3_k127_5766690_71 Bacterial SH3 domain - - - 0.00000000000018 78.0
REGS3_k127_5766690_72 Tfp pilus assembly protein FimV - - - 0.00001535 53.0
REGS3_k127_5766690_8 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 9.765e-222 694.0
REGS3_k127_5766690_9 CHASE2 K01768 - 4.6.1.1 2.52e-217 690.0
REGS3_k127_5789744_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 471.0
REGS3_k127_5789744_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 414.0
REGS3_k127_5789744_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 328.0
REGS3_k127_5789744_3 Sodium:solute symporter family K14393 - - 0.0000000000000000004379 87.0
REGS3_k127_5789744_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000006766 78.0
REGS3_k127_6012202_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1084.0
REGS3_k127_6012202_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 5.038e-303 966.0
REGS3_k127_6012202_10 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 391.0
REGS3_k127_6012202_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 381.0
REGS3_k127_6012202_12 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 373.0
REGS3_k127_6012202_13 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
REGS3_k127_6012202_14 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007818 266.0
REGS3_k127_6012202_15 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002973 254.0
REGS3_k127_6012202_16 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
REGS3_k127_6012202_17 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000001841 212.0
REGS3_k127_6012202_18 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000827 189.0
REGS3_k127_6012202_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000002571 166.0
REGS3_k127_6012202_2 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 4.252e-263 815.0
REGS3_k127_6012202_20 RDD family - - - 0.00000000000000000000000000000000000001247 149.0
REGS3_k127_6012202_21 Pfam Glutaredoxin - - - 0.0000000000000000000000000000000000008347 146.0
REGS3_k127_6012202_22 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000007067 115.0
REGS3_k127_6012202_23 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000315 111.0
REGS3_k127_6012202_24 Outer membrane efflux protein K12340 - - 0.000000000005531 71.0
REGS3_k127_6012202_25 Protein of unknown function (DUF3619) - - - 0.000001071 58.0
REGS3_k127_6012202_3 TIGRFAM nitrogen regulation protein NR(I) K07712 - - 1.951e-225 707.0
REGS3_k127_6012202_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.948e-217 681.0
REGS3_k127_6012202_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 5.992e-206 651.0
REGS3_k127_6012202_6 dihydroorotase K01465 - 3.5.2.3 3.938e-203 640.0
REGS3_k127_6012202_7 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 524.0
REGS3_k127_6012202_8 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 455.0
REGS3_k127_6012202_9 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 401.0
REGS3_k127_6015846_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1300.0
REGS3_k127_6015846_1 Rieske 2Fe-2S K05710 - - 0.000000000000000000000000000000000000001034 149.0
REGS3_k127_6026971_0 Large family of predicted nucleotide-binding domains K07175 - - 1.375e-262 814.0
REGS3_k127_6026971_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.349e-229 718.0
REGS3_k127_6026971_10 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000001919 223.0
REGS3_k127_6026971_11 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
REGS3_k127_6026971_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000007896 200.0
REGS3_k127_6026971_13 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000007933 174.0
REGS3_k127_6026971_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000001263 151.0
REGS3_k127_6026971_15 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000144 153.0
REGS3_k127_6026971_16 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000002752 85.0
REGS3_k127_6026971_17 Tfp pilus assembly protein FimV K08086 - - 0.000000000007504 78.0
REGS3_k127_6026971_18 Sulfatase - - - 0.00000006154 56.0
REGS3_k127_6026971_2 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 584.0
REGS3_k127_6026971_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 550.0
REGS3_k127_6026971_4 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 480.0
REGS3_k127_6026971_5 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 450.0
REGS3_k127_6026971_6 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 446.0
REGS3_k127_6026971_7 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 387.0
REGS3_k127_6026971_8 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 332.0
REGS3_k127_6026971_9 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000005576 231.0
REGS3_k127_6032289_0 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 546.0
REGS3_k127_6032289_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 428.0
REGS3_k127_6032289_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 442.0
REGS3_k127_6032289_3 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 415.0
REGS3_k127_6032289_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
REGS3_k127_6032289_5 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000000000000000000000007275 225.0
REGS3_k127_6032289_6 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.0000000000000000009603 87.0
REGS3_k127_60362_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 8.794e-236 750.0
REGS3_k127_60362_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.436e-213 669.0
REGS3_k127_60362_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000002204 183.0
REGS3_k127_60362_11 - - - - 0.000000000000006255 80.0
REGS3_k127_60362_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 520.0
REGS3_k127_60362_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 512.0
REGS3_k127_60362_4 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 454.0
REGS3_k127_60362_5 CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 421.0
REGS3_k127_60362_6 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 317.0
REGS3_k127_60362_7 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
REGS3_k127_60362_8 - K09004 - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
REGS3_k127_60362_9 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000004045 202.0
REGS3_k127_6051002_0 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 496.0
REGS3_k127_6051002_1 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 447.0
REGS3_k127_6051002_10 diol metabolic process K01724 - 4.2.1.96 0.00000000000000000000000000000000000000004003 156.0
REGS3_k127_6051002_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 414.0
REGS3_k127_6051002_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 359.0
REGS3_k127_6051002_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 359.0
REGS3_k127_6051002_5 Short-chain dehydrogenase reductase sdr K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 312.0
REGS3_k127_6051002_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 297.0
REGS3_k127_6051002_7 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005331 261.0
REGS3_k127_6051002_8 EXOIII K13288 - - 0.000000000000000000000000000000000000000000000000000000000000001076 242.0
REGS3_k127_6051002_9 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000003791 211.0
REGS3_k127_6051100_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 563.0
REGS3_k127_6051100_1 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 473.0
REGS3_k127_6051100_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 368.0
REGS3_k127_6051100_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
REGS3_k127_6051100_4 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000001088 231.0
REGS3_k127_6051100_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000002915 209.0
REGS3_k127_6051100_6 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000000000000000000000000000479 185.0
REGS3_k127_6051100_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000006547 153.0
REGS3_k127_6051100_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000001068 143.0
REGS3_k127_6069307_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 517.0
REGS3_k127_6069307_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 386.0
REGS3_k127_6069307_2 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000003049 138.0
REGS3_k127_6069307_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000006732 61.0
REGS3_k127_6069307_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000001287 59.0
REGS3_k127_6069307_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000001752 59.0
REGS3_k127_6077195_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 606.0
REGS3_k127_6077195_1 COG1271 Cytochrome bd-type quinol oxidase, subunit 1 K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 574.0
REGS3_k127_6077195_10 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000001376 64.0
REGS3_k127_6077195_2 oxidase, subunit II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 381.0
REGS3_k127_6077195_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
REGS3_k127_6077195_4 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007237 276.0
REGS3_k127_6077195_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001398 250.0
REGS3_k127_6077195_6 - - - - 0.0000000000000000000000000000000000001088 145.0
REGS3_k127_6077195_7 - - - - 0.00000000000003183 79.0
REGS3_k127_6077195_8 - - - - 0.0000000000002715 77.0
REGS3_k127_6077195_9 - - - - 0.00000000001455 70.0
REGS3_k127_6079286_0 Bacterial protein of unknown function (DUF853) - - - 5.403e-222 698.0
REGS3_k127_6079286_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 580.0
REGS3_k127_6079286_10 TonB C terminal - - - 0.000000000000000000000000657 118.0
REGS3_k127_6079286_11 OmpA-like transmembrane domain K03286 - - 0.0000000000000000000000016 113.0
REGS3_k127_6079286_2 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 402.0
REGS3_k127_6079286_3 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 324.0
REGS3_k127_6079286_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 320.0
REGS3_k127_6079286_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
REGS3_k127_6079286_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000008803 262.0
REGS3_k127_6079286_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001342 255.0
REGS3_k127_6079286_8 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000009277 166.0
REGS3_k127_6079286_9 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000003388 147.0
REGS3_k127_6080747_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.6e-206 649.0
REGS3_k127_6080747_1 Peptidogalycan biosysnthesis/recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 449.0
REGS3_k127_6080747_2 Belongs to the arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 377.0
REGS3_k127_6080747_3 MltA-interacting protein MipA K07274 - - 0.0000000000000000000000000000000000000000009668 168.0
REGS3_k127_6085922_0 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 541.0
REGS3_k127_6085922_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 491.0
REGS3_k127_6085922_10 - - - - 0.000000000000000000000000000007449 123.0
REGS3_k127_6085922_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000000008788 112.0
REGS3_k127_6085922_12 - - - - 0.0000000000000000000000005129 118.0
REGS3_k127_6085922_13 - - - - 0.0000000001459 64.0
REGS3_k127_6085922_2 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 378.0
REGS3_k127_6085922_3 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001916 243.0
REGS3_k127_6085922_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000006245 213.0
REGS3_k127_6085922_5 methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000004606 195.0
REGS3_k127_6085922_6 - - - - 0.000000000000000000000000000000000000000000000013 179.0
REGS3_k127_6085922_7 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000009763 161.0
REGS3_k127_6085922_8 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000003881 137.0
REGS3_k127_6085922_9 Cupredoxin-like domain - - - 0.000000000000000000000000000000002694 132.0
REGS3_k127_6115375_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 476.0
REGS3_k127_6115375_1 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 362.0
REGS3_k127_6115375_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
REGS3_k127_6115375_3 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009858 243.0
REGS3_k127_6115375_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000002024 183.0
REGS3_k127_6115375_5 Redoxin domain protein - - - 0.000000000000000000000003315 109.0
REGS3_k127_6125056_0 Adenosine/AMP deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 481.0
REGS3_k127_6125056_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 458.0
REGS3_k127_6125056_2 Guanine deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000002329 142.0
REGS3_k127_6125056_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000002538 124.0
REGS3_k127_6125056_4 Guanine deaminase K01487 - 3.5.4.3 0.00000525 50.0
REGS3_k127_6139807_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 2.19e-208 661.0
REGS3_k127_6139807_1 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 525.0
REGS3_k127_6139807_2 TatD related DNase K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 504.0
REGS3_k127_6139807_3 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000002963 222.0
REGS3_k127_6179440_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.429e-272 848.0
REGS3_k127_6179440_1 ABC transporter transmembrane region - - - 1.95e-268 844.0
REGS3_k127_6179440_10 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 351.0
REGS3_k127_6179440_11 UPF0761 membrane protein K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 346.0
REGS3_k127_6179440_12 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 331.0
REGS3_k127_6179440_13 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
REGS3_k127_6179440_14 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 299.0
REGS3_k127_6179440_15 PFAM O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 296.0
REGS3_k127_6179440_16 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 294.0
REGS3_k127_6179440_17 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 291.0
REGS3_k127_6179440_18 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 289.0
REGS3_k127_6179440_19 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
REGS3_k127_6179440_2 - - - - 5.358e-201 638.0
REGS3_k127_6179440_20 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002444 259.0
REGS3_k127_6179440_21 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006878 244.0
REGS3_k127_6179440_22 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002331 239.0
REGS3_k127_6179440_23 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004286 233.0
REGS3_k127_6179440_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006862 231.0
REGS3_k127_6179440_25 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000267 228.0
REGS3_k127_6179440_26 Protein of unknown function (DUF2470) K07226 - - 0.0000000000000000000000000000000000000000000000000000001324 204.0
REGS3_k127_6179440_27 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000002977 202.0
REGS3_k127_6179440_28 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000001297 189.0
REGS3_k127_6179440_29 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000001259 188.0
REGS3_k127_6179440_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 572.0
REGS3_k127_6179440_30 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000001744 175.0
REGS3_k127_6179440_31 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000001318 176.0
REGS3_k127_6179440_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000003816 170.0
REGS3_k127_6179440_33 Transcriptional regulator, MarR - - - 0.0000000000000000000000000000000000000000003292 163.0
REGS3_k127_6179440_34 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000000000000001211 160.0
REGS3_k127_6179440_35 PFAM Acetyltransferase (GNAT) family K03824 - - 0.00000000000000000000000000000000002704 140.0
REGS3_k127_6179440_36 Phasin protein - - - 0.00000000000000000000000000000001936 132.0
REGS3_k127_6179440_37 Guanyl-specific ribonuclease Sa - - - 0.00000000000000000000000000000007745 132.0
REGS3_k127_6179440_38 Glycosyl transferases group 1 - - - 0.00000000000000000000006787 112.0
REGS3_k127_6179440_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 572.0
REGS3_k127_6179440_41 (Barnase) inhibitor - - - 0.00000000000000529 82.0
REGS3_k127_6179440_43 - - - - 0.0000000144 65.0
REGS3_k127_6179440_5 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 566.0
REGS3_k127_6179440_6 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 465.0
REGS3_k127_6179440_7 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 463.0
REGS3_k127_6179440_8 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 392.0
REGS3_k127_6179440_9 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 356.0
REGS3_k127_6244787_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 599.0
REGS3_k127_6244787_1 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000006236 218.0
REGS3_k127_6244787_2 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000003006 214.0
REGS3_k127_6244787_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000858 63.0
REGS3_k127_6251614_0 Methylmalonyl-CoA mutase K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 7.207e-304 936.0
REGS3_k127_6251614_1 PFAM Copper resistance D K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 395.0
REGS3_k127_6251614_10 - - - - 0.000000009354 59.0
REGS3_k127_6251614_11 glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.0003083 51.0
REGS3_k127_6251614_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 379.0
REGS3_k127_6251614_3 Monooxygenase subunit B protein K10945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 355.0
REGS3_k127_6251614_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001013 275.0
REGS3_k127_6251614_5 Ammonia monooxygenase/methane monooxygenase, subunit C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002574 268.0
REGS3_k127_6251614_6 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005422 257.0
REGS3_k127_6251614_7 Ammonia monooxygenase K10944 - 1.14.18.3,1.14.99.39 0.00000000000000000000000000000000000000000000000000000000000002759 223.0
REGS3_k127_6251614_8 - - - - 0.0000000000000000000000000000000000000000000000000000003556 203.0
REGS3_k127_6251614_9 PFAM Copper resistance protein CopC K07156 - - 0.00000000000000000000000003801 111.0
REGS3_k127_6253719_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1539.0
REGS3_k127_6253719_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1501.0
REGS3_k127_6253719_10 50S ribosomal protein L4 K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 298.0
REGS3_k127_6253719_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 286.0
REGS3_k127_6253719_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004981 267.0
REGS3_k127_6253719_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002211 239.0
REGS3_k127_6253719_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000006377 235.0
REGS3_k127_6253719_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
REGS3_k127_6253719_16 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000003631 230.0
REGS3_k127_6253719_17 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000002555 223.0
REGS3_k127_6253719_18 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000001789 213.0
REGS3_k127_6253719_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000002486 213.0
REGS3_k127_6253719_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.262e-235 732.0
REGS3_k127_6253719_20 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000003198 201.0
REGS3_k127_6253719_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000007955 182.0
REGS3_k127_6253719_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000004747 172.0
REGS3_k127_6253719_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000006491 170.0
REGS3_k127_6253719_24 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000000000001527 168.0
REGS3_k127_6253719_25 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000003397 169.0
REGS3_k127_6253719_26 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000007719 162.0
REGS3_k127_6253719_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000004279 145.0
REGS3_k127_6253719_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000819 123.0
REGS3_k127_6253719_29 Ribosomal protein L30 K02907 - - 0.00000000000000000001185 93.0
REGS3_k127_6253719_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 561.0
REGS3_k127_6253719_30 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000238 88.0
REGS3_k127_6253719_31 structural constituent of ribosome K02919 - - 0.000000000001202 73.0
REGS3_k127_6253719_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 499.0
REGS3_k127_6253719_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 474.0
REGS3_k127_6253719_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 419.0
REGS3_k127_6253719_7 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 402.0
REGS3_k127_6253719_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
REGS3_k127_6253719_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 301.0
REGS3_k127_6277375_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1194.0
REGS3_k127_6277375_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 6.415e-299 931.0
REGS3_k127_6277375_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 470.0
REGS3_k127_6277375_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 393.0
REGS3_k127_6277375_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 366.0
REGS3_k127_6277375_5 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 334.0
REGS3_k127_6277375_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001114 244.0
REGS3_k127_6277375_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000004562 221.0
REGS3_k127_6277375_8 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000000005651 209.0
REGS3_k127_6316026_0 Dehydratase family K22186 - 4.2.1.82 2.447e-305 946.0
REGS3_k127_6316026_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 2.179e-284 889.0
REGS3_k127_6316026_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 442.0
REGS3_k127_6316026_11 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 432.0
REGS3_k127_6316026_12 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 408.0
REGS3_k127_6316026_13 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 376.0
REGS3_k127_6316026_14 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 376.0
REGS3_k127_6316026_15 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 352.0
REGS3_k127_6316026_16 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 322.0
REGS3_k127_6316026_17 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 282.0
REGS3_k127_6316026_18 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000001044 142.0
REGS3_k127_6316026_19 Protein of unknown function (DUF3995) - - - 0.000000000000000000000000008245 115.0
REGS3_k127_6316026_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 3.687e-252 784.0
REGS3_k127_6316026_21 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000002388 97.0
REGS3_k127_6316026_22 Diguanylate cyclase - - - 0.00000000006714 64.0
REGS3_k127_6316026_23 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000002758 63.0
REGS3_k127_6316026_3 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 3.547e-233 731.0
REGS3_k127_6316026_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 2.183e-213 673.0
REGS3_k127_6316026_5 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 609.0
REGS3_k127_6316026_6 4Fe-4S double cluster binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 582.0
REGS3_k127_6316026_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 562.0
REGS3_k127_6316026_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 537.0
REGS3_k127_6316026_9 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 466.0
REGS3_k127_6341228_0 FMN-dependent alpha-hydroxy acid dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 383.0
REGS3_k127_6341228_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 345.0
REGS3_k127_6341228_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
REGS3_k127_6341228_3 Predicted membrane protein (DUF2127) - - - 0.0000000000000000000000000000000000000000002083 170.0
REGS3_k127_6341228_4 Domain of unknown function (DUF1993) K09983 - - 0.000000000000009246 74.0
REGS3_k127_6354962_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 1.546e-222 722.0
REGS3_k127_6354962_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 518.0
REGS3_k127_6354962_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 382.0
REGS3_k127_6354962_3 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 349.0
REGS3_k127_6354962_4 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 316.0
REGS3_k127_6354962_5 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000009434 191.0
REGS3_k127_6356957_0 urea carboxylase-associated protein 1 K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 344.0
REGS3_k127_6356957_1 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
REGS3_k127_6356957_2 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.00000000000001318 74.0
REGS3_k127_6368303_0 PFAM AMP-dependent synthetase K12508 - 6.2.1.34 2.642e-226 717.0
REGS3_k127_6368303_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000188 139.0
REGS3_k127_6368303_2 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000000502 130.0
REGS3_k127_6390908_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 417.0
REGS3_k127_6415970_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1084.0
REGS3_k127_6415970_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 3.466e-260 828.0
REGS3_k127_6415970_10 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 362.0
REGS3_k127_6415970_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 346.0
REGS3_k127_6415970_12 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
REGS3_k127_6415970_13 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
REGS3_k127_6415970_14 Uroporphyrin-III C tetrapyrrole K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
REGS3_k127_6415970_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000001084 244.0
REGS3_k127_6415970_16 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000002384 244.0
REGS3_k127_6415970_17 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000008717 227.0
REGS3_k127_6415970_18 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
REGS3_k127_6415970_19 virion core protein, lumpy skin disease virus - - - 0.00000000000000000000000000000000000000000000000000000006906 203.0
REGS3_k127_6415970_2 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 5.095e-205 644.0
REGS3_k127_6415970_20 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000000003777 195.0
REGS3_k127_6415970_21 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000003533 150.0
REGS3_k127_6415970_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000044 136.0
REGS3_k127_6415970_23 rieske 2fe-2s - - - 0.0000000000000000000000000000000003306 136.0
REGS3_k127_6415970_24 Ribosomal L32p protein family - - - 0.0000000000000000000000000001302 119.0
REGS3_k127_6415970_25 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000000000000000000003061 116.0
REGS3_k127_6415970_26 alpha/beta hydrolase fold K01563 - 3.8.1.5 0.0000000000000000008594 88.0
REGS3_k127_6415970_3 Aminotransferase class I and II K00832 - 2.6.1.57 8.974e-198 622.0
REGS3_k127_6415970_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 478.0
REGS3_k127_6415970_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 473.0
REGS3_k127_6415970_6 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 445.0
REGS3_k127_6415970_7 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 402.0
REGS3_k127_6415970_8 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 389.0
REGS3_k127_6415970_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 377.0
REGS3_k127_6418939_0 urea carboxylase K01941 - 6.3.4.6 0.0 1769.0
REGS3_k127_6418939_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01457 - 3.5.1.54 7.609e-245 769.0
REGS3_k127_6418939_2 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 537.0
REGS3_k127_6418939_3 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 373.0
REGS3_k127_6429226_0 Acyl-CoA dehydrogenase N terminal K00249 - 1.3.8.7 4.934e-240 754.0
REGS3_k127_6429226_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.557e-199 629.0
REGS3_k127_6491273_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 543.0
REGS3_k127_6491273_1 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 485.0
REGS3_k127_6491273_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 300.0
REGS3_k127_6491273_3 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 296.0
REGS3_k127_6491273_4 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000004155 163.0
REGS3_k127_6491273_5 - - - - 0.000000000002211 79.0
REGS3_k127_65007_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1035.0
REGS3_k127_65007_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.239e-237 742.0
REGS3_k127_65007_10 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 327.0
REGS3_k127_65007_11 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003237 281.0
REGS3_k127_65007_12 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001897 292.0
REGS3_k127_65007_13 MobA-Related Protein K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000005209 199.0
REGS3_k127_65007_14 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000000000000000000000000000002951 194.0
REGS3_k127_65007_15 YaeQ - - - 0.0000000000000000000000000000000000000000000000001552 178.0
REGS3_k127_65007_16 Haem-degrading - - - 0.00000000000000000000000000000000000000000000004313 175.0
REGS3_k127_65007_17 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000654 168.0
REGS3_k127_65007_18 Trm112p-like protein K09791 - - 0.000000000000002827 76.0
REGS3_k127_65007_19 - - - - 0.00001217 53.0
REGS3_k127_65007_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.45e-220 689.0
REGS3_k127_65007_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.526e-219 695.0
REGS3_k127_65007_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 500.0
REGS3_k127_65007_5 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 501.0
REGS3_k127_65007_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
REGS3_k127_65007_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 365.0
REGS3_k127_65007_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 343.0
REGS3_k127_65007_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 329.0
REGS3_k127_6531405_0 proteasome-type protease K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 375.0
REGS3_k127_6531405_1 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 387.0
REGS3_k127_6531405_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003986 278.0
REGS3_k127_6531405_3 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000637 124.0
REGS3_k127_6531405_4 Periplasmic or secreted lipoprotein K04065 - - 0.00000000000000001359 85.0
REGS3_k127_6531405_5 Belongs to the N-Me-Phe pilin family K02650 - - 0.0001022 49.0
REGS3_k127_653976_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.415e-300 926.0
REGS3_k127_653976_1 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 439.0
REGS3_k127_653976_10 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000009375 225.0
REGS3_k127_653976_11 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000005286 203.0
REGS3_k127_653976_12 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000003746 182.0
REGS3_k127_653976_13 Integral membrane protein (DUF2244) - - - 0.00000000000000000000000003061 117.0
REGS3_k127_653976_14 Protein of unknown function (DUF2909) - - - 0.00000000000000003433 86.0
REGS3_k127_653976_15 Protein of unknown function (DUF2970) - - - 0.000000000007233 68.0
REGS3_k127_653976_16 Belongs to the peptidase M16 family K07263 - - 0.00000000003253 73.0
REGS3_k127_653976_2 SRP54-type protein, helical bundle domain K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 434.0
REGS3_k127_653976_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 406.0
REGS3_k127_653976_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 398.0
REGS3_k127_653976_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 392.0
REGS3_k127_653976_6 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 321.0
REGS3_k127_653976_7 protein required for cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 324.0
REGS3_k127_653976_8 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 308.0
REGS3_k127_653976_9 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000026 240.0
REGS3_k127_6573929_0 PFAM SNF2-related protein K08282 - 2.7.11.1 0.0 1032.0
REGS3_k127_65843_0 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 563.0
REGS3_k127_65843_1 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 560.0
REGS3_k127_65843_2 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 537.0
REGS3_k127_65843_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 434.0
REGS3_k127_65843_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 399.0
REGS3_k127_65843_5 abc transporter K01995,K10822 - 3.6.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 325.0
REGS3_k127_65843_6 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 324.0
REGS3_k127_65843_7 regulator IclR - - - 0.0000000000000000000000000000000000000000000000000000000000004026 235.0
REGS3_k127_662912_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 476.0
REGS3_k127_662912_1 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000006562 192.0
REGS3_k127_662912_2 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000746 184.0
REGS3_k127_662912_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000003019 154.0
REGS3_k127_662912_4 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000004333 135.0
REGS3_k127_662912_5 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000008775 125.0
REGS3_k127_662912_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000007807 118.0
REGS3_k127_662912_7 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000000000007597 67.0
REGS3_k127_6631292_0 ABC1 family K03688 - - 2.876e-222 701.0
REGS3_k127_6631292_1 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000004603 147.0
REGS3_k127_6631292_2 - - - - 0.00000000000000000009725 94.0
REGS3_k127_6631292_3 - - - - 0.000000000000000009133 89.0
REGS3_k127_6631292_4 - - - - 0.0000003013 54.0
REGS3_k127_6632019_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.537e-275 857.0
REGS3_k127_6632019_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.682e-207 651.0
REGS3_k127_6632019_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 589.0
REGS3_k127_6632019_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 442.0
REGS3_k127_6632019_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 362.0
REGS3_k127_6632019_5 Psort location CytoplasmicMembrane, score 10.00 K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 283.0
REGS3_k127_6632019_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000177 219.0
REGS3_k127_6632019_7 preprotein translocase K03210 - - 0.00000000000000000000000000000000008732 136.0
REGS3_k127_66363_0 Response regulator receiver K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 360.0
REGS3_k127_66363_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003394 252.0
REGS3_k127_66363_2 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
REGS3_k127_66363_3 response regulator K02282,K07705 - - 0.00000000000000000000002149 105.0
REGS3_k127_6643922_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 4.208e-289 895.0
REGS3_k127_6643922_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 6.558e-224 704.0
REGS3_k127_6643922_2 Alpha/beta hydrolase family K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 351.0
REGS3_k127_6643922_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 302.0
REGS3_k127_6643922_5 - - - - 0.000000000000000001596 89.0
REGS3_k127_6655199_0 - - - - 0.000000000000000000000000000000000000000000000000000000003668 207.0
REGS3_k127_6715838_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0 1049.0
REGS3_k127_6715838_1 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 5.575e-248 782.0
REGS3_k127_6715838_2 Glycosyl hydrolase family 57 - - - 3.398e-225 711.0
REGS3_k127_6715838_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.34e-210 666.0
REGS3_k127_6715838_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 402.0
REGS3_k127_6715838_5 Phosphopantetheine attachment site - - - 0.000000000000000001331 97.0
REGS3_k127_6715838_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000007036 79.0
REGS3_k127_6715838_7 - - - - 0.00000000003312 70.0
REGS3_k127_6872850_0 Type II/IV secretion system protein K02454 - - 4.129e-247 787.0
REGS3_k127_6872850_1 secretion system protein K02453 - - 1.466e-222 705.0
REGS3_k127_6872850_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 588.0
REGS3_k127_6872850_3 Domain of unknown function (DUF3943) - - - 0.00000000000000000000003599 101.0
REGS3_k127_6880795_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009853 273.0
REGS3_k127_6880795_1 AraC-like ligand binding domain - - - 0.000000000000000000000000000001057 125.0
REGS3_k127_6880795_2 Sel1-like repeats. K07126 - - 0.000000000000000000000000229 112.0
REGS3_k127_6880795_3 Protein of unknown function (DUF962) - - - 0.000000000000000000000002759 107.0
REGS3_k127_6880795_4 Amidohydrolase K07045 - - 0.00000005062 56.0
REGS3_k127_6880795_5 - - - - 0.000001171 51.0
REGS3_k127_6888689_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 533.0
REGS3_k127_6888689_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000008031 267.0
REGS3_k127_6888689_2 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000001675 94.0
REGS3_k127_6899429_0 peptidase M20 - - - 3.814e-197 625.0
REGS3_k127_6899429_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0004395 45.0
REGS3_k127_6907073_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1369.0
REGS3_k127_6907073_1 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.095e-196 625.0
REGS3_k127_6907073_10 Sporulation related domain - - - 0.000000000002954 72.0
REGS3_k127_6907073_11 HlyD family K01993 - - 0.000000001351 61.0
REGS3_k127_6907073_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 622.0
REGS3_k127_6907073_3 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 570.0
REGS3_k127_6907073_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 520.0
REGS3_k127_6907073_5 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 446.0
REGS3_k127_6907073_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 366.0
REGS3_k127_6907073_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 353.0
REGS3_k127_6907073_8 PFAM Tripartite ATP-independent periplasmic transporter DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000001976 228.0
REGS3_k127_6907073_9 Cytochrome c - - - 0.00000000000000000000000000005773 124.0
REGS3_k127_6910159_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 4.82e-237 747.0
REGS3_k127_6910159_1 PFAM DNA photolyase FAD-binding K01669 - 4.1.99.3 1.512e-196 627.0
REGS3_k127_6910159_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000005624 156.0
REGS3_k127_6910159_11 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000003533 150.0
REGS3_k127_6910159_12 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000004822 137.0
REGS3_k127_6910159_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000001685 119.0
REGS3_k127_6910159_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000001643 109.0
REGS3_k127_6910159_15 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000002259 86.0
REGS3_k127_6910159_17 B12 binding domain K22491 - - 0.00000000000003877 74.0
REGS3_k127_6910159_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 511.0
REGS3_k127_6910159_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 484.0
REGS3_k127_6910159_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 404.0
REGS3_k127_6910159_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 317.0
REGS3_k127_6910159_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 306.0
REGS3_k127_6910159_7 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001643 284.0
REGS3_k127_6910159_8 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000002729 205.0
REGS3_k127_6910159_9 transport-associated - - - 0.000000000000000000000000000000000000000000000000000281 190.0
REGS3_k127_6921259_0 Heat shock 70 kDa protein K04043 - - 0.0 1041.0
REGS3_k127_6921259_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.865e-256 797.0
REGS3_k127_6921259_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 379.0
REGS3_k127_6921259_11 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 319.0
REGS3_k127_6921259_12 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
REGS3_k127_6921259_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001879 274.0
REGS3_k127_6921259_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000657 262.0
REGS3_k127_6921259_15 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002022 241.0
REGS3_k127_6921259_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000003564 213.0
REGS3_k127_6921259_17 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000001512 156.0
REGS3_k127_6921259_18 Colicin V production K03558 - - 0.000000000000000000000000000000000002935 144.0
REGS3_k127_6921259_19 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000007448 117.0
REGS3_k127_6921259_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 9.744e-222 694.0
REGS3_k127_6921259_20 Bacterial protein of unknown function (DUF922) - - - 0.00000000000000000000000004316 117.0
REGS3_k127_6921259_21 Sporulation related domain K03749 - - 0.0000000000001075 74.0
REGS3_k127_6921259_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 619.0
REGS3_k127_6921259_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 601.0
REGS3_k127_6921259_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 597.0
REGS3_k127_6921259_6 Ferrochelatase K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 512.0
REGS3_k127_6921259_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 479.0
REGS3_k127_6921259_8 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 475.0
REGS3_k127_6921259_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 396.0
REGS3_k127_6931608_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.627e-258 810.0
REGS3_k127_6931608_1 FAD dependent oxidoreductase - - - 7.32e-251 783.0
REGS3_k127_6931608_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 331.0
REGS3_k127_6931608_11 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 337.0
REGS3_k127_6931608_12 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 336.0
REGS3_k127_6931608_13 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 321.0
REGS3_k127_6931608_14 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005307 279.0
REGS3_k127_6931608_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000006382 248.0
REGS3_k127_6931608_16 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000345 232.0
REGS3_k127_6931608_17 Dehydroquinase class II - - - 0.00000000000000000000000000000000000000000000000005242 181.0
REGS3_k127_6931608_18 - - - - 0.00000000000000000000000000000000000000000000003241 181.0
REGS3_k127_6931608_19 Cupin - - - 0.000000000000000000000000000000000000000008793 157.0
REGS3_k127_6931608_2 FAD dependent oxidoreductase - - - 1.56e-204 649.0
REGS3_k127_6931608_20 Endoribonuclease L-PSP - - - 0.0000000000000000000000002042 110.0
REGS3_k127_6931608_21 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000005094 83.0
REGS3_k127_6931608_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02035 - - 1.115e-201 637.0
REGS3_k127_6931608_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 527.0
REGS3_k127_6931608_5 ABC transporter K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 535.0
REGS3_k127_6931608_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 442.0
REGS3_k127_6931608_7 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 471.0
REGS3_k127_6931608_8 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 364.0
REGS3_k127_6931608_9 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 356.0
REGS3_k127_6934481_0 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 512.0
REGS3_k127_6934481_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000001808 229.0
REGS3_k127_6934481_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000002093 206.0
REGS3_k127_6934481_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000002609 203.0
REGS3_k127_6934481_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000008897 140.0
REGS3_k127_6934481_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001067 145.0
REGS3_k127_6934481_6 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000008527 108.0
REGS3_k127_6934481_7 PFAM Bile acid sodium symporter K03325 - - 0.000000001951 62.0
REGS3_k127_6934481_8 Major intrinsic protein - - - 0.00000003902 57.0
REGS3_k127_6935305_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1422.0
REGS3_k127_6935305_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1040.0
REGS3_k127_6935305_10 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 580.0
REGS3_k127_6935305_11 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 525.0
REGS3_k127_6935305_12 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 452.0
REGS3_k127_6935305_13 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 431.0
REGS3_k127_6935305_14 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 421.0
REGS3_k127_6935305_15 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 396.0
REGS3_k127_6935305_16 RNA polymerase sigma factor K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 385.0
REGS3_k127_6935305_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 338.0
REGS3_k127_6935305_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 334.0
REGS3_k127_6935305_19 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 323.0
REGS3_k127_6935305_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.753e-307 962.0
REGS3_k127_6935305_20 PFAM MgtC SapB transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 324.0
REGS3_k127_6935305_21 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 299.0
REGS3_k127_6935305_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
REGS3_k127_6935305_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001637 276.0
REGS3_k127_6935305_24 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003157 282.0
REGS3_k127_6935305_25 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009385 269.0
REGS3_k127_6935305_26 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 261.0
REGS3_k127_6935305_27 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000887 261.0
REGS3_k127_6935305_28 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001692 243.0
REGS3_k127_6935305_29 luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001013 231.0
REGS3_k127_6935305_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 4.031e-267 848.0
REGS3_k127_6935305_30 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000008819 225.0
REGS3_k127_6935305_31 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000006704 226.0
REGS3_k127_6935305_32 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000016 201.0
REGS3_k127_6935305_33 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000001151 197.0
REGS3_k127_6935305_34 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000008807 188.0
REGS3_k127_6935305_35 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000001524 186.0
REGS3_k127_6935305_36 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000003264 190.0
REGS3_k127_6935305_37 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000001219 176.0
REGS3_k127_6935305_38 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002637 150.0
REGS3_k127_6935305_39 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000001475 145.0
REGS3_k127_6935305_4 Belongs to the glutamate synthase family - - - 1.167e-254 792.0
REGS3_k127_6935305_40 Ribosomal protein L35 K02916 - - 0.00000000000000000195 86.0
REGS3_k127_6935305_41 Pfam Response regulator receiver K07689 - - 0.00000000000000006966 85.0
REGS3_k127_6935305_42 - - - - 0.0000000002006 66.0
REGS3_k127_6935305_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.907e-233 741.0
REGS3_k127_6935305_6 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.286e-231 728.0
REGS3_k127_6935305_7 Aminotransferase K14261 - - 6.664e-230 716.0
REGS3_k127_6935305_8 homoserine dehydrogenase K00003 - 1.1.1.3 2.391e-226 709.0
REGS3_k127_6935305_9 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 598.0
REGS3_k127_6936112_0 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
REGS3_k127_6937158_0 GTP-binding protein K06207 - - 7.4e-323 996.0
REGS3_k127_6937158_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 7.775e-262 832.0
REGS3_k127_6937158_10 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000000000000000001118 190.0
REGS3_k127_6937158_11 ubiE/COQ5 methyltransferase family - - - 0.000001563 54.0
REGS3_k127_6937158_12 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.00005496 50.0
REGS3_k127_6937158_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 519.0
REGS3_k127_6937158_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 414.0
REGS3_k127_6937158_4 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 307.0
REGS3_k127_6937158_5 PFAM Response regulator receiver domain, Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 306.0
REGS3_k127_6937158_6 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 287.0
REGS3_k127_6937158_7 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008013 256.0
REGS3_k127_6937158_8 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000002499 218.0
REGS3_k127_6937158_9 Thiopurine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007174 202.0
REGS3_k127_6948741_0 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K19270 - 3.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 273.0
REGS3_k127_6948741_1 PFAM 17 kDa surface antigen - - - 0.0000000000000000000000000000001471 131.0
REGS3_k127_6955380_0 PQQ-like domain K17760 - 1.1.9.1 1.317e-217 690.0
REGS3_k127_6955380_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 579.0
REGS3_k127_6955380_10 TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 329.0
REGS3_k127_6955380_11 glycosyl transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 337.0
REGS3_k127_6955380_12 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 321.0
REGS3_k127_6955380_13 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 322.0
REGS3_k127_6955380_14 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 315.0
REGS3_k127_6955380_15 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 287.0
REGS3_k127_6955380_16 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 284.0
REGS3_k127_6955380_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002419 270.0
REGS3_k127_6955380_18 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000219 250.0
REGS3_k127_6955380_19 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001151 233.0
REGS3_k127_6955380_2 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 565.0
REGS3_k127_6955380_20 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
REGS3_k127_6955380_21 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002073 227.0
REGS3_k127_6955380_22 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000718 226.0
REGS3_k127_6955380_23 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000002185 188.0
REGS3_k127_6955380_24 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000003499 186.0
REGS3_k127_6955380_25 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000007115 141.0
REGS3_k127_6955380_26 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.000000000000000000000000000000000004828 154.0
REGS3_k127_6955380_27 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000001665 141.0
REGS3_k127_6955380_28 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000157 136.0
REGS3_k127_6955380_29 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000004349 98.0
REGS3_k127_6955380_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 535.0
REGS3_k127_6955380_30 MAATS-type transcriptional repressor, C-terminal region K03577 - - 0.00000000000000000002416 93.0
REGS3_k127_6955380_31 AI-2E family transporter - - - 0.00000000000000001333 89.0
REGS3_k127_6955380_32 MAATS-type transcriptional repressor, C-terminal region K03577,K18135 - - 0.0000000000005997 73.0
REGS3_k127_6955380_33 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000263 64.0
REGS3_k127_6955380_34 AI-2E family transporter - - - 0.000002591 56.0
REGS3_k127_6955380_35 Belongs to the bacterial solute-binding protein 3 family K02030,K02424 - - 0.00008826 53.0
REGS3_k127_6955380_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 511.0
REGS3_k127_6955380_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 511.0
REGS3_k127_6955380_6 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 422.0
REGS3_k127_6955380_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 342.0
REGS3_k127_6955380_8 FecCD transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 337.0
REGS3_k127_6955380_9 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 332.0
REGS3_k127_6959608_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 390.0
REGS3_k127_6959608_1 Short-chain dehydrogenase reductase sdr K00059,K07535 - 1.1.1.100 0.000000000000001636 79.0
REGS3_k127_696156_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 535.0
REGS3_k127_696156_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 312.0
REGS3_k127_696156_2 Peptidase M50 K16922 - - 0.000000000000000000000000000000000000000000000000000000000000001399 227.0
REGS3_k127_696156_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000175 239.0
REGS3_k127_696156_4 Trypsin - - - 0.00000000000000000000000008983 113.0
REGS3_k127_6969405_0 taurine dioxygenase K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 368.0
REGS3_k127_6969405_1 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000002079 231.0
REGS3_k127_6969405_2 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000000000000000008943 175.0
REGS3_k127_6969405_3 Trypsin-like peptidase domain - - - 0.0001648 50.0
REGS3_k127_6978659_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.783e-278 868.0
REGS3_k127_6978659_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.548e-207 655.0
REGS3_k127_6978659_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 307.0
REGS3_k127_6978659_11 PFAM Methionine biosynthesis MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007377 295.0
REGS3_k127_6978659_12 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000299 210.0
REGS3_k127_6978659_13 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000002713 161.0
REGS3_k127_6978659_14 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000001625 145.0
REGS3_k127_6978659_15 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001703 112.0
REGS3_k127_6978659_16 Domain of unknown function (DUF4124) - - - 0.00000000000000000000003184 108.0
REGS3_k127_6978659_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 2.848e-202 633.0
REGS3_k127_6978659_3 AmpG muropeptide MFS transporter K08218 K08218 - - 4.122e-202 636.0
REGS3_k127_6978659_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 601.0
REGS3_k127_6978659_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 583.0
REGS3_k127_6978659_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 547.0
REGS3_k127_6978659_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 493.0
REGS3_k127_6978659_8 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 400.0
REGS3_k127_6978659_9 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 323.0
REGS3_k127_7021028_0 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 336.0
REGS3_k127_7021028_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 313.0
REGS3_k127_7021028_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000001359 175.0
REGS3_k127_7050116_0 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 614.0
REGS3_k127_7050116_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 333.0
REGS3_k127_7050116_10 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000000006873 139.0
REGS3_k127_7050116_11 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000006399 134.0
REGS3_k127_7050116_12 Cytochrome c - - - 0.000000000000000000000000003608 115.0
REGS3_k127_7050116_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 329.0
REGS3_k127_7050116_3 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007058 282.0
REGS3_k127_7050116_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001306 249.0
REGS3_k127_7050116_5 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000002814 252.0
REGS3_k127_7050116_6 Sulphur oxidation protein SoxZ K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
REGS3_k127_7050116_7 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000004591 184.0
REGS3_k127_7050116_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000002672 185.0
REGS3_k127_7050116_9 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000001972 138.0
REGS3_k127_7051411_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000003757 187.0
REGS3_k127_7051411_1 Bacterial periplasmic substrate-binding proteins - - - 0.0000000001793 72.0
REGS3_k127_7051411_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000001339 60.0
REGS3_k127_7065697_0 PQQ enzyme repeat - - - 7.658e-263 811.0
REGS3_k127_7065697_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 5.786e-213 683.0
REGS3_k127_7065697_10 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000125 227.0
REGS3_k127_7065697_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000003805 184.0
REGS3_k127_7065697_12 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000004077 192.0
REGS3_k127_7065697_13 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000601 168.0
REGS3_k127_7065697_14 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000007037 170.0
REGS3_k127_7065697_15 Protein of unknown function (DUF2380) - - - 0.00000000000000000000000000000001531 132.0
REGS3_k127_7065697_16 - - - - 0.0000000000000000000000000007558 116.0
REGS3_k127_7065697_17 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000004569 72.0
REGS3_k127_7065697_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.475e-197 623.0
REGS3_k127_7065697_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 443.0
REGS3_k127_7065697_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 400.0
REGS3_k127_7065697_5 SMART extracellular solute-binding protein, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 315.0
REGS3_k127_7065697_6 Belongs to the HpcH HpaI aldolase family K01630,K02510 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0008150,GO:0008152,GO:0016829,GO:0016830,GO:0016832,GO:0044238,GO:0044424,GO:0044464,GO:0071704 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 311.0
REGS3_k127_7065697_7 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 300.0
REGS3_k127_7065697_8 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 293.0
REGS3_k127_7065697_9 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005134 257.0
REGS3_k127_7089435_0 belongs to the aldehyde dehydrogenase family K00130,K00146 - 1.2.1.39,1.2.1.8 8.854e-245 763.0
REGS3_k127_7089435_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 588.0
REGS3_k127_7089435_2 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 289.0
REGS3_k127_7089435_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002137 261.0
REGS3_k127_7089435_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006085 225.0
REGS3_k127_7095406_0 TonB-dependent receptor K02014 - - 2.362e-238 759.0
REGS3_k127_7095406_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 4.066e-218 686.0
REGS3_k127_7095406_2 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 314.0
REGS3_k127_7095406_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005012 259.0
REGS3_k127_7095406_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000002529 238.0
REGS3_k127_7095406_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000007948 193.0
REGS3_k127_7095406_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000158 198.0
REGS3_k127_7095406_7 - - - - 0.0000000000000000000000000000000000000000007591 163.0
REGS3_k127_7103472_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 421.0
REGS3_k127_7103472_1 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000002437 220.0
REGS3_k127_7115483_0 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 348.0
REGS3_k127_7115483_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000475 297.0
REGS3_k127_7115483_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003291 240.0
REGS3_k127_7115483_3 protein conserved in bacteria K09780 - - 0.00000001023 56.0
REGS3_k127_712125_0 Dihydrodipicolinate synthetase family K13876 - 4.2.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 353.0
REGS3_k127_712125_1 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000003416 184.0
REGS3_k127_712125_2 Bile acid sodium symporter K03453 - - 0.0000000000000000000002115 108.0
REGS3_k127_712125_4 Protein of unknown function (DUF465) - - - 0.000000000006362 68.0
REGS3_k127_712366_0 Aminotransferase class-III K00823 - 2.6.1.19 3.533e-236 739.0
REGS3_k127_712366_1 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 376.0
REGS3_k127_712366_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 322.0
REGS3_k127_712366_3 HAD-superfamily hydrolase, subfamily IB K08966 - 3.1.3.87 0.000000000000000000000000000000000000000000000000000000000000009072 224.0
REGS3_k127_712366_4 MltA-interacting protein MipA K07274 - - 0.0000000000000000000000000000000000000000002043 169.0
REGS3_k127_712366_5 Multidrug Resistance protein K03297 - - 0.000000000000000000001441 102.0
REGS3_k127_712366_6 Multidrug Resistance protein K12962 - - 0.000000000000000004298 87.0
REGS3_k127_7129867_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.0 1493.0
REGS3_k127_7129867_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.542e-271 845.0
REGS3_k127_7129867_10 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004888 261.0
REGS3_k127_7129867_11 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000933 244.0
REGS3_k127_7129867_12 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000002015 214.0
REGS3_k127_7129867_13 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000344 171.0
REGS3_k127_7129867_14 - - - - 0.0000000000000000000000000000000004547 147.0
REGS3_k127_7129867_15 Carbohydrate-selective porin, OprB family - - - 0.00000000000000000000000000001861 124.0
REGS3_k127_7129867_16 Putative transmembrane protein (PGPGW) - - - 0.000000000000000000000001814 105.0
REGS3_k127_7129867_17 Carbohydrate-selective porin, OprB family - - - 0.0000000000000000000002703 104.0
REGS3_k127_7129867_2 ABC-type sugar transport system, periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 567.0
REGS3_k127_7129867_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 514.0
REGS3_k127_7129867_4 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 482.0
REGS3_k127_7129867_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 442.0
REGS3_k127_7129867_6 PFAM fumarylacetoacetate (FAA) hydrolase K16856,K18336 - 4.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 406.0
REGS3_k127_7129867_7 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 376.0
REGS3_k127_7129867_8 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 343.0
REGS3_k127_7129867_9 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 339.0
REGS3_k127_7135344_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 380.0
REGS3_k127_7135344_1 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 378.0
REGS3_k127_7135344_2 Putative oxidoreductase C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 336.0
REGS3_k127_7135344_3 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 313.0
REGS3_k127_7135344_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 309.0
REGS3_k127_7135344_5 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000001039 227.0
REGS3_k127_7135344_6 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000002475 198.0
REGS3_k127_7135344_7 - - - - 0.00001072 49.0
REGS3_k127_7135344_8 Domain of unknown function (DUF4440) - - - 0.0001422 45.0
REGS3_k127_7139028_0 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 565.0
REGS3_k127_7139028_1 Pfam:DUF1446 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 522.0
REGS3_k127_7139028_10 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
REGS3_k127_7139028_11 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000002164 227.0
REGS3_k127_7139028_12 - - - - 0.00000000000000000000000000000000000000000000000000000004367 203.0
REGS3_k127_7139028_13 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000001924 169.0
REGS3_k127_7139028_14 Haem-degrading - - - 0.00000000000000000000000000000000000000009979 154.0
REGS3_k127_7139028_15 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000000000000371 153.0
REGS3_k127_7139028_16 - - - - 0.00000000000000000000000000000000003309 141.0
REGS3_k127_7139028_17 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000007991 126.0
REGS3_k127_7139028_18 - - - - 0.00000000000000000000000002206 113.0
REGS3_k127_7139028_19 UPF0391 membrane protein - - - 0.0000000000000001538 80.0
REGS3_k127_7139028_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 509.0
REGS3_k127_7139028_20 Cupin 2, conserved barrel domain protein - - - 0.0000000000003417 77.0
REGS3_k127_7139028_21 AI-2E family transporter - - - 0.00000000006526 69.0
REGS3_k127_7139028_22 endonuclease - - - 0.0000000004945 61.0
REGS3_k127_7139028_3 Major Facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 473.0
REGS3_k127_7139028_4 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 407.0
REGS3_k127_7139028_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 388.0
REGS3_k127_7139028_6 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 338.0
REGS3_k127_7139028_7 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 310.0
REGS3_k127_7139028_8 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001324 249.0
REGS3_k127_7139028_9 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
REGS3_k127_7145770_0 Papain family cysteine protease - - - 1.031e-299 936.0
REGS3_k127_7145770_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 433.0
REGS3_k127_7145770_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 319.0
REGS3_k127_7145770_3 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 319.0
REGS3_k127_7145770_4 S4 domain K14761 - - 0.0000000000000000000006205 98.0
REGS3_k127_7145770_5 Transcriptional regulator - - - 0.000000000000000001174 93.0
REGS3_k127_7145770_6 SlyX K03745 - - 0.0000000000000004233 82.0
REGS3_k127_714605_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 564.0
REGS3_k127_714605_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 391.0
REGS3_k127_714605_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 373.0
REGS3_k127_714605_3 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 328.0
REGS3_k127_714605_4 AIR carboxylase K06898 - - 0.000000000004622 69.0
REGS3_k127_7169639_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 597.0
REGS3_k127_7169639_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 361.0
REGS3_k127_7169639_2 phytanoyl-CoA dioxygenase K00477 - 1.14.11.18 0.00000000000000000000000000000000000000000000000000000000148 205.0
REGS3_k127_7176284_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 3.703e-260 820.0
REGS3_k127_7176284_1 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 608.0
REGS3_k127_7176284_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 460.0
REGS3_k127_7176284_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 454.0
REGS3_k127_7176284_4 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 442.0
REGS3_k127_7176284_5 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 372.0
REGS3_k127_7176284_6 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 355.0
REGS3_k127_7182893_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1785.0
REGS3_k127_7182893_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.497e-272 850.0
REGS3_k127_7182893_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 8.239e-259 809.0
REGS3_k127_7182893_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 570.0
REGS3_k127_7182893_4 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 297.0
REGS3_k127_7182893_5 transcriptional K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002554 245.0
REGS3_k127_7182893_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001419 131.0
REGS3_k127_7184777_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.293e-211 666.0
REGS3_k127_7184777_1 PFAM General substrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 553.0
REGS3_k127_7184777_10 Belongs to the ompA family K03640 - - 0.0000000000000000000000000008525 124.0
REGS3_k127_7184777_2 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 300.0
REGS3_k127_7184777_3 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 297.0
REGS3_k127_7184777_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000003052 248.0
REGS3_k127_7184777_5 Aldolase/RraA K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000001002 245.0
REGS3_k127_7184777_6 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000001192 206.0
REGS3_k127_7184777_7 TPM domain - - - 0.0000000000000000000000000000000000000001316 158.0
REGS3_k127_7184777_8 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000000001839 159.0
REGS3_k127_7184777_9 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000006755 121.0
REGS3_k127_71855_0 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 530.0
REGS3_k127_71855_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 512.0
REGS3_k127_71855_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003854 272.0
REGS3_k127_71855_11 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009392 272.0
REGS3_k127_71855_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000002006 170.0
REGS3_k127_71855_13 - - - - 0.00000000000000000000000000000000000000000123 170.0
REGS3_k127_71855_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 468.0
REGS3_k127_71855_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 460.0
REGS3_k127_71855_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 439.0
REGS3_k127_71855_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 397.0
REGS3_k127_71855_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 408.0
REGS3_k127_71855_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 377.0
REGS3_k127_71855_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 346.0
REGS3_k127_71855_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 328.0
REGS3_k127_7191443_0 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 488.0
REGS3_k127_7191443_1 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
REGS3_k127_7191443_2 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002347 271.0
REGS3_k127_7191443_3 Enoyl-CoA hydratase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000003989 109.0
REGS3_k127_7191443_4 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000004075 66.0
REGS3_k127_7199670_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 4.735e-295 916.0
REGS3_k127_7199670_1 heat shock protein binding - - - 4.103e-230 729.0
REGS3_k127_7199670_10 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 336.0
REGS3_k127_7199670_11 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 318.0
REGS3_k127_7199670_12 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 313.0
REGS3_k127_7199670_13 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009241 274.0
REGS3_k127_7199670_14 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000002523 226.0
REGS3_k127_7199670_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000001556 218.0
REGS3_k127_7199670_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000005813 209.0
REGS3_k127_7199670_17 alpha beta - - - 0.00000000000000000000000000000000000000000000000000003461 198.0
REGS3_k127_7199670_18 - - - - 0.00000000000000000000000000000000000000000000000000003478 199.0
REGS3_k127_7199670_19 YqeY-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000007568 187.0
REGS3_k127_7199670_2 PFAM type II secretion system K02653 - - 1.761e-197 621.0
REGS3_k127_7199670_20 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000001068 183.0
REGS3_k127_7199670_21 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000001646 181.0
REGS3_k127_7199670_22 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000005255 141.0
REGS3_k127_7199670_23 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000004391 129.0
REGS3_k127_7199670_24 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000000004063 114.0
REGS3_k127_7199670_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 5.321e-196 621.0
REGS3_k127_7199670_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 8.636e-194 621.0
REGS3_k127_7199670_5 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 553.0
REGS3_k127_7199670_6 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 496.0
REGS3_k127_7199670_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 458.0
REGS3_k127_7199670_8 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 413.0
REGS3_k127_7199670_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 395.0
REGS3_k127_7207026_0 ABC-type sugar transport system, periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 465.0
REGS3_k127_7207026_1 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
REGS3_k127_7207026_2 phosphatidylcholine synthase activity K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 333.0
REGS3_k127_7207026_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 308.0
REGS3_k127_7207026_4 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000004814 223.0
REGS3_k127_7211171_0 PFAM mannose-6-phosphate isomerase, type II K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 466.0
REGS3_k127_7227074_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 529.0
REGS3_k127_7227074_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 495.0
REGS3_k127_7227074_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 488.0
REGS3_k127_7227074_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 384.0
REGS3_k127_7227074_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003398 251.0
REGS3_k127_7227074_5 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000007015 209.0
REGS3_k127_7227074_6 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000002821 215.0
REGS3_k127_7227074_7 FAD binding domain - - - 0.00000000000000000000000001165 120.0
REGS3_k127_7276253_0 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 524.0
REGS3_k127_7276253_1 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 412.0
REGS3_k127_7276253_2 Glycosyltransferase Family 4 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 355.0
REGS3_k127_7276253_3 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 325.0
REGS3_k127_7276253_4 asparagine K01953 - 6.3.5.4 0.00000000000000000000000000009549 117.0
REGS3_k127_7320121_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 1.433e-321 1003.0
REGS3_k127_7320121_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.423e-232 730.0
REGS3_k127_7320121_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 589.0
REGS3_k127_7320121_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 494.0
REGS3_k127_7320121_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008279 267.0
REGS3_k127_7320121_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002719 246.0
REGS3_k127_7329390_0 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 369.0
REGS3_k127_7329390_1 NMT1 THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 349.0
REGS3_k127_7329390_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004194 232.0
REGS3_k127_7329390_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000002144 85.0
REGS3_k127_734295_0 glutaminyl-tRNA K01886 - 6.1.1.18 6.349e-279 870.0
REGS3_k127_734295_1 Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000004866 241.0
REGS3_k127_7367567_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 5.426e-232 726.0
REGS3_k127_7432641_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.126e-249 770.0
REGS3_k127_7432641_1 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000398 239.0
REGS3_k127_7432641_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000000001789 213.0
REGS3_k127_7432641_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000006068 192.0
REGS3_k127_7432641_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000002248 56.0
REGS3_k127_7455893_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 578.0
REGS3_k127_7646563_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 366.0
REGS3_k127_7646563_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000152 206.0
REGS3_k127_7729075_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.694e-302 953.0
REGS3_k127_7729075_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000006986 125.0
REGS3_k127_7735705_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 1.657e-220 689.0
REGS3_k127_7735705_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 317.0
REGS3_k127_7753086_0 Protein of unknown function (DUF1800) - - - 4.794e-257 805.0
REGS3_k127_7753086_1 Twin-arginine translocation pathway signal sequence - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 574.0
REGS3_k127_7753086_10 Histidine kinase-like ATPase domain - - - 0.000000000000002082 83.0
REGS3_k127_7753086_11 Metallo-beta-lactamase superfamily - - - 0.000000000003851 67.0
REGS3_k127_7753086_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 589.0
REGS3_k127_7753086_3 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 465.0
REGS3_k127_7753086_4 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 394.0
REGS3_k127_7753086_5 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 303.0
REGS3_k127_7753086_6 FecR protein - - - 0.00000000000000000000000000000000000004662 148.0
REGS3_k127_7753086_7 OmpA family - - - 0.0000000000000000000000000000000000003576 149.0
REGS3_k127_7753086_8 - - - - 0.00000000000000000000000001158 116.0
REGS3_k127_7753086_9 STAS domain K06378 - - 0.00000000000000000000002165 106.0
REGS3_k127_7771050_0 AcyL-CoA dehydrogenase K06445 - - 7.32e-313 979.0
REGS3_k127_7771050_1 AMP-binding enzyme C-terminal domain K00666 - - 1.043e-258 806.0
REGS3_k127_7771050_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
REGS3_k127_7771050_11 Thioesterase superfamily protein K10806 - - 0.000000000000000000000000000000000000000000000000008632 183.0
REGS3_k127_7771050_12 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000006006 123.0
REGS3_k127_7771050_13 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000005579 116.0
REGS3_k127_7771050_2 COG1960 Acyl-CoA dehydrogenases K20035 - - 4.06e-256 801.0
REGS3_k127_7771050_3 AMP-dependent synthetase K01897 - 6.2.1.3 1.849e-227 719.0
REGS3_k127_7771050_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 452.0
REGS3_k127_7771050_5 Electron transfer flavoprotein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 391.0
REGS3_k127_7771050_6 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 398.0
REGS3_k127_7771050_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 370.0
REGS3_k127_7771050_8 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 301.0
REGS3_k127_7771050_9 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
REGS3_k127_7777498_0 - - - - 2.616e-220 702.0
REGS3_k127_7777498_1 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 510.0
REGS3_k127_7777498_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 297.0
REGS3_k127_7777498_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000165 275.0
REGS3_k127_7780174_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 492.0
REGS3_k127_7780174_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 442.0
REGS3_k127_7780174_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 334.0
REGS3_k127_7780174_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000001137 145.0
REGS3_k127_7780174_4 PFAM Phosphoribosyltransferase - - - 0.00000000000002287 83.0
REGS3_k127_7801683_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000005158 145.0
REGS3_k127_7801683_1 - - - - 0.000000000000000000000000006937 119.0
REGS3_k127_7801683_2 Polysaccharide lyase - - - 0.00000000004377 73.0
REGS3_k127_7801942_0 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
REGS3_k127_7801942_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000005931 160.0
REGS3_k127_7801942_2 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000001443 168.0
REGS3_k127_780515_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 7.191e-304 945.0
REGS3_k127_780515_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 567.0
REGS3_k127_780515_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 527.0
REGS3_k127_780515_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 448.0
REGS3_k127_780515_4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 430.0
REGS3_k127_780515_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 427.0
REGS3_k127_780515_6 depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000205 235.0
REGS3_k127_780515_7 - - - - 0.0000000000000000000001988 101.0
REGS3_k127_7821410_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.636e-301 930.0
REGS3_k127_7821410_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.31e-206 651.0
REGS3_k127_7821410_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 441.0
REGS3_k127_7821410_3 SMART CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 420.0
REGS3_k127_7821410_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002773 280.0
REGS3_k127_7821410_5 - - - - 0.000000000000000000000000000000000000000000000000000001403 199.0
REGS3_k127_7821410_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000459 171.0
REGS3_k127_7824954_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 3.095e-213 674.0
REGS3_k127_7826296_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 299.0
REGS3_k127_7826296_1 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000002073 116.0
REGS3_k127_7826296_2 ABC transporter substrate binding protein K01989 - - 0.0000000001598 64.0
REGS3_k127_7826296_3 Cytochrome c - - - 0.000000001762 58.0
REGS3_k127_7832128_0 Homospermidine synthase K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 612.0
REGS3_k127_7832128_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 506.0
REGS3_k127_7832128_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 435.0
REGS3_k127_7832128_3 Cytochrome C' - - - 0.0000000000000000000000000000002749 127.0
REGS3_k127_7834824_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 463.0
REGS3_k127_7834824_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 447.0
REGS3_k127_7834824_2 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001027 271.0
REGS3_k127_7834824_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000008764 148.0
REGS3_k127_7863001_0 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K00520 - 1.16.1.1 0.0 1166.0
REGS3_k127_7863001_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 5e-227 713.0
REGS3_k127_7863001_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 5.23e-208 651.0
REGS3_k127_7863001_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 584.0
REGS3_k127_7863001_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 466.0
REGS3_k127_7863001_5 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
REGS3_k127_7863001_6 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000001826 225.0
REGS3_k127_7902775_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.007e-221 692.0
REGS3_k127_7902775_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 463.0
REGS3_k127_7902775_2 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 459.0
REGS3_k127_7902775_3 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 447.0
REGS3_k127_7902775_4 PFAM Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 321.0
REGS3_k127_7902775_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 296.0
REGS3_k127_7902775_6 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000000000000000000000000004698 192.0
REGS3_k127_7902775_7 PFAM Peptidase C13 - - - 0.000000000000000000000001312 115.0
REGS3_k127_7902775_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000002604 98.0
REGS3_k127_7907634_0 Malic enzyme K00029 - 1.1.1.40 0.0 1126.0
REGS3_k127_7907634_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 482.0
REGS3_k127_7907634_2 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 480.0
REGS3_k127_7907634_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000003656 73.0
REGS3_k127_7907634_4 Conserved TM helix - - - 0.0000000000000729 75.0
REGS3_k127_7910292_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 373.0
REGS3_k127_7910292_1 PFAM type II secretion system K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
REGS3_k127_7910292_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000003246 229.0
REGS3_k127_7910292_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000001736 201.0
REGS3_k127_7910292_4 Virulence factor membrane-bound polymerase, C-terminal - - - 0.00000000000000000000000000000000000000000000007619 180.0
REGS3_k127_7910292_5 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000298 152.0
REGS3_k127_7910292_6 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000226 147.0
REGS3_k127_7910292_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000009748 139.0
REGS3_k127_7958060_0 Bacterial transcriptional activator domain - - - 3.411e-222 726.0
REGS3_k127_7978188_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 318.0
REGS3_k127_7978188_1 response regulator - - - 0.0000000000000000000000000000000000000000000408 168.0
REGS3_k127_7978188_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0004226 45.0
REGS3_k127_8036624_0 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 514.0
REGS3_k127_8036624_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 485.0
REGS3_k127_8036624_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 383.0
REGS3_k127_8041385_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 533.0
REGS3_k127_8041385_1 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 544.0
REGS3_k127_8041385_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000037 253.0
REGS3_k127_8041385_11 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000002014 192.0
REGS3_k127_8041385_12 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000007373 139.0
REGS3_k127_8041385_2 transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 503.0
REGS3_k127_8041385_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 403.0
REGS3_k127_8041385_4 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 383.0
REGS3_k127_8041385_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 348.0
REGS3_k127_8041385_6 PFAM Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 297.0
REGS3_k127_8041385_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002672 274.0
REGS3_k127_8041385_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 258.0
REGS3_k127_8041385_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000004287 256.0
REGS3_k127_8056750_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.659e-241 757.0
REGS3_k127_8056750_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 489.0
REGS3_k127_8056750_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 458.0
REGS3_k127_8056750_3 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 439.0
REGS3_k127_8056750_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 328.0
REGS3_k127_8056750_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
REGS3_k127_8056750_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
REGS3_k127_8056750_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000004363 156.0
REGS3_k127_8056750_8 - - - - 0.00000000002077 66.0
REGS3_k127_8084815_0 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 602.0
REGS3_k127_8084815_1 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 281.0
REGS3_k127_8084815_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
REGS3_k127_8125493_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 395.0
REGS3_k127_8125493_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
REGS3_k127_8125493_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000007163 171.0
REGS3_k127_8125493_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000003474 159.0
REGS3_k127_8125493_4 Belongs to the ompA family K03640 - - 0.000000000000000000000000000008781 119.0
REGS3_k127_8125493_5 Mycolic acid cyclopropane synthetase - - - 0.00000000000006507 74.0
REGS3_k127_8138212_0 Sulfite reductase, beta subunit (Hemoprotein) K00381,K00392 - 1.8.1.2,1.8.7.1 1.931e-267 833.0
REGS3_k127_8138212_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.96e-231 728.0
REGS3_k127_8138212_10 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000004229 103.0
REGS3_k127_8138212_11 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000052 71.0
REGS3_k127_8138212_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 525.0
REGS3_k127_8138212_3 adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 500.0
REGS3_k127_8138212_4 Bacterial regulatory helix-turn-helix protein, lysR family K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 477.0
REGS3_k127_8138212_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 329.0
REGS3_k127_8138212_6 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 315.0
REGS3_k127_8138212_7 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000003826 233.0
REGS3_k127_8138212_8 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000000000000000000000000000000005325 195.0
REGS3_k127_8138212_9 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000008745 182.0
REGS3_k127_8141412_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 519.0
REGS3_k127_8141412_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000004296 176.0
REGS3_k127_8141412_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000004971 87.0
REGS3_k127_8231208_0 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 400.0
REGS3_k127_8231208_1 Belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003022 256.0
REGS3_k127_8231208_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000002254 243.0
REGS3_k127_8231208_3 Aspartyl/Asparaginyl beta-hydroxylase K00476 - 1.14.11.16 0.0000000000000000000000000000000000000000000000000000000000001397 220.0
REGS3_k127_8231208_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000002205 208.0
REGS3_k127_8231208_5 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000007011 151.0
REGS3_k127_8244359_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 4.615e-199 625.0
REGS3_k127_8244359_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 569.0
REGS3_k127_8244359_10 Protein of unknown function (DUF2905) - - - 0.00000000000000533 76.0
REGS3_k127_8244359_11 EF-hand, calcium binding motif - - - 0.000002623 55.0
REGS3_k127_8244359_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 516.0
REGS3_k127_8244359_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 431.0
REGS3_k127_8244359_4 transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 403.0
REGS3_k127_8244359_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 334.0
REGS3_k127_8244359_6 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 321.0
REGS3_k127_8244359_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 286.0
REGS3_k127_8244359_8 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000001742 233.0
REGS3_k127_8244359_9 membrane protein, terc - - - 0.0000000000000000000000000000000000000000000000000000000000000002065 228.0
REGS3_k127_8261555_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 534.0
REGS3_k127_8261555_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 491.0
REGS3_k127_8261555_2 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 400.0
REGS3_k127_8261555_3 Peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002387 257.0
REGS3_k127_8261555_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 257.0
REGS3_k127_8261555_5 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000006659 252.0
REGS3_k127_8261555_6 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000001347 213.0
REGS3_k127_8261555_7 copper resistance - - - 0.000005206 49.0
REGS3_k127_8448297_0 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 554.0
REGS3_k127_8448297_1 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 318.0
REGS3_k127_8448297_2 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001275 239.0
REGS3_k127_8448297_3 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000002164 162.0
REGS3_k127_8448297_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000000009205 144.0
REGS3_k127_8448297_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000003734 105.0
REGS3_k127_8448297_6 - - - - 0.0000000000000002691 80.0
REGS3_k127_8549427_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 587.0
REGS3_k127_8549427_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 500.0
REGS3_k127_8549427_2 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
REGS3_k127_8549427_3 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000003113 83.0
REGS3_k127_8550361_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 609.0
REGS3_k127_8550361_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008375 269.0
REGS3_k127_8550361_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000001878 177.0
REGS3_k127_8550361_3 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000138 61.0
REGS3_k127_85564_0 Pfam:KaiC K08482 - - 4.264e-225 707.0
REGS3_k127_85564_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 477.0
REGS3_k127_85564_2 - - - - 0.00000000000000004095 85.0
REGS3_k127_866343_0 HAD-hyrolase-like K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000101 231.0
REGS3_k127_866343_1 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000001759 171.0
REGS3_k127_866380_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 586.0
REGS3_k127_866380_1 - K18700 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042802,GO:0042803,GO:0046983 3.1.2.29 0.0000000000000000000000000000000000000000000000000001278 190.0
REGS3_k127_866380_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000007993 178.0
REGS3_k127_866380_3 MASE1 - - - 0.000000000000000000000000000000000000181 164.0
REGS3_k127_866380_4 cheY-homologous receiver domain - - - 0.0000000000000000008068 102.0
REGS3_k127_873405_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1287.0
REGS3_k127_873405_1 Helicase K03657 - 3.6.4.12 3.37e-321 997.0
REGS3_k127_873405_10 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000001981 119.0
REGS3_k127_873405_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 419.0
REGS3_k127_873405_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 411.0
REGS3_k127_873405_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 351.0
REGS3_k127_873405_5 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000729 221.0
REGS3_k127_873405_6 - - - - 0.0000000000000000000000000000000000000000000001026 180.0
REGS3_k127_873405_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000004385 158.0
REGS3_k127_873405_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000005379 153.0
REGS3_k127_873405_9 4Fe-4S binding domain - - - 0.00000000000000000000000000000000007104 135.0
REGS3_k127_873407_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.842e-203 637.0
REGS3_k127_873407_1 Sporulation related domain - - - 0.000000000002489 71.0
REGS3_k127_874536_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1097.0
REGS3_k127_874536_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1070.0
REGS3_k127_874536_10 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 287.0
REGS3_k127_874536_11 metal-dependent phosphoesterases (PHP family) K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000004418 266.0
REGS3_k127_874536_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006803 248.0
REGS3_k127_874536_13 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000002 210.0
REGS3_k127_874536_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000002251 195.0
REGS3_k127_874536_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000008976 177.0
REGS3_k127_874536_16 - - - - 0.0000000000000000000000000000000000000000004636 157.0
REGS3_k127_874536_17 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000001815 159.0
REGS3_k127_874536_18 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000007536 140.0
REGS3_k127_874536_19 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000001639 78.0
REGS3_k127_874536_2 L-lactate permease K00427,K03303 - - 1.486e-257 805.0
REGS3_k127_874536_20 Tripartite tricarboxylate transporter TctA K07793 - - 0.000000000007302 70.0
REGS3_k127_874536_21 Tripartite tricarboxylate transporter TctB family - - - 0.000000003874 63.0
REGS3_k127_874536_3 Participates in both transcription termination and antitermination K02600 - - 3.511e-247 770.0
REGS3_k127_874536_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.144e-243 762.0
REGS3_k127_874536_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 7.498e-228 710.0
REGS3_k127_874536_6 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.078e-204 648.0
REGS3_k127_874536_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 378.0
REGS3_k127_874536_8 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 318.0
REGS3_k127_874536_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 302.0
REGS3_k127_879234_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 576.0
REGS3_k127_879234_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 545.0
REGS3_k127_879234_2 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 359.0
REGS3_k127_879234_3 50S ribosomal protein L21 K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 280.0
REGS3_k127_879234_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000002586 241.0
REGS3_k127_879234_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000002149 125.0
REGS3_k127_879234_6 - - - - 0.0000000000000000000000005995 109.0
REGS3_k127_882272_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 9.971e-245 788.0
REGS3_k127_882272_1 protein conserved in bacteria K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 584.0
REGS3_k127_882272_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 509.0
REGS3_k127_896082_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 571.0
REGS3_k127_896082_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 282.0
REGS3_k127_896082_2 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004779 244.0
REGS3_k127_896082_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.000000000000000000000000000000001246 133.0
REGS3_k127_896082_4 - - - - 0.000000000000000000000002731 104.0
REGS3_k127_896082_5 - - - - 0.0000000000000002558 83.0
REGS3_k127_896082_6 SNARE associated Golgi protein - - - 0.000001289 52.0
REGS3_k127_944196_0 L-lactate permease K03303 - - 2.711e-213 676.0
REGS3_k127_944196_1 aldo keto reductase K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 473.0
REGS3_k127_944196_2 13-prostaglandin reductase activity K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 415.0
REGS3_k127_944196_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000001588 203.0
REGS3_k127_944196_4 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000002448 89.0
REGS3_k127_944196_5 - - - - 0.0000000000002922 72.0
REGS3_k127_944196_6 Protein of unknown function (DUF3567) - - - 0.0000000000004018 73.0
REGS3_k127_945152_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 309.0
REGS3_k127_945152_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 284.0
REGS3_k127_945152_2 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006079 297.0
REGS3_k127_945152_3 - - - - 0.000000003482 59.0
REGS3_k127_960923_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 574.0
REGS3_k127_960923_1 PFAM sigma-54 factor interaction domain-containing protein K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 573.0
REGS3_k127_960923_10 histone deacetylase - - - 0.00000002662 59.0
REGS3_k127_960923_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 518.0
REGS3_k127_960923_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 498.0
REGS3_k127_960923_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 430.0
REGS3_k127_960923_5 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 349.0
REGS3_k127_960923_6 Ami_2 K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003235 250.0
REGS3_k127_960923_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000001003 162.0
REGS3_k127_960923_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000002869 153.0
REGS3_k127_960923_9 - K06950 - - 0.0000000008182 64.0
REGS3_k127_963745_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 4.759e-311 961.0
REGS3_k127_963745_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 7.033e-304 943.0
REGS3_k127_963745_10 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000001614 221.0
REGS3_k127_963745_11 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000009347 213.0
REGS3_k127_963745_12 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000003935 185.0
REGS3_k127_963745_13 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000000021 178.0
REGS3_k127_963745_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000001453 164.0
REGS3_k127_963745_15 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000001726 168.0
REGS3_k127_963745_16 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000005931 61.0
REGS3_k127_963745_17 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000006792 48.0
REGS3_k127_963745_2 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 545.0
REGS3_k127_963745_3 AsmA family K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 472.0
REGS3_k127_963745_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 424.0
REGS3_k127_963745_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 393.0
REGS3_k127_963745_6 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 356.0
REGS3_k127_963745_7 COG0501 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 332.0
REGS3_k127_963745_8 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001289 277.0
REGS3_k127_963745_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001063 243.0
REGS3_k127_966427_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1782.0
REGS3_k127_966427_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 388.0
REGS3_k127_966427_10 BolA-like protein K05527 - - 0.000000000000000000000000008606 115.0
REGS3_k127_966427_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 364.0
REGS3_k127_966427_3 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001619 268.0
REGS3_k127_966427_4 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000009285 261.0
REGS3_k127_966427_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
REGS3_k127_966427_6 Peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000448 206.0
REGS3_k127_966427_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000004971 165.0
REGS3_k127_966427_8 YCII-related domain K09780 - - 0.0000000000000000000000000000000005463 141.0
REGS3_k127_966427_9 PIN domain - - - 0.000000000000000000000000001037 121.0
REGS3_k127_984981_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1294.0
REGS3_k127_984981_1 MMPL family - - - 0.0 1245.0
REGS3_k127_984981_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 517.0
REGS3_k127_984981_11 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 495.0
REGS3_k127_984981_12 Inositol-1-monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 377.0
REGS3_k127_984981_13 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
REGS3_k127_984981_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 370.0
REGS3_k127_984981_15 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 346.0
REGS3_k127_984981_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 343.0
REGS3_k127_984981_17 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
REGS3_k127_984981_18 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 327.0
REGS3_k127_984981_19 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 338.0
REGS3_k127_984981_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1e-323 1005.0
REGS3_k127_984981_20 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 316.0
REGS3_k127_984981_21 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 292.0
REGS3_k127_984981_22 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 300.0
REGS3_k127_984981_23 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002403 275.0
REGS3_k127_984981_24 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000002064 254.0
REGS3_k127_984981_25 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000004061 249.0
REGS3_k127_984981_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000001557 222.0
REGS3_k127_984981_27 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000002245 229.0
REGS3_k127_984981_28 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000009142 200.0
REGS3_k127_984981_29 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000004518 197.0
REGS3_k127_984981_3 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.249e-308 953.0
REGS3_k127_984981_30 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000004322 161.0
REGS3_k127_984981_31 Belongs to the thioredoxin family K03671 - - 0.0000001308 59.0
REGS3_k127_984981_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.018e-245 766.0
REGS3_k127_984981_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 7.958e-241 757.0
REGS3_k127_984981_6 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 594.0
REGS3_k127_984981_7 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 601.0
REGS3_k127_984981_8 TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. Interpro FAD-dependent pyridine K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 589.0
REGS3_k127_984981_9 transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 596.0
REGS3_k127_986795_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1352.0
REGS3_k127_986795_1 PAS fold - - - 2.041e-293 923.0
REGS3_k127_986795_2 Outer membrane efflux protein K18903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 426.0
REGS3_k127_986795_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 402.0
REGS3_k127_986795_5 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C - - - 0.000000000000000000000000000007662 130.0
REGS3_k127_997988_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 2.48e-272 846.0
REGS3_k127_997988_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 411.0
REGS3_k127_997988_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 345.0
REGS3_k127_997988_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 320.0
REGS3_k127_997988_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 331.0
REGS3_k127_997988_5 acetyltransferase K00661 - 2.3.1.79 0.000000000000000000000000003203 111.0