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Overview

ID MAG03364
Name SHD1_bin.17
Sample SMP0082
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Terriglobales
Family Korobacteraceae
Genus DASPLH01
Species
Assembly information
Completeness (%) 78.84
Contamination (%) 5.59
GC content (%) 57.0
N50 (bp) 6,400
Genome size (bp) 3,128,039

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2889

Gene name Description KEGG GOs EC E-value Score Sequence
SHD1_k127_1006598_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006508 280.0
SHD1_k127_1006598_1 Cupin - - - 0.0000000000000000000000000000000000000000327 157.0
SHD1_k127_1006598_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000004205 142.0
SHD1_k127_1006598_3 peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000003986 97.0
SHD1_k127_1007009_0 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 573.0
SHD1_k127_1007009_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 431.0
SHD1_k127_1007009_2 Peptidase, M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 417.0
SHD1_k127_1007009_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 392.0
SHD1_k127_1007009_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 311.0
SHD1_k127_1011152_0 Amidohydrolase family - - - 1.364e-214 674.0
SHD1_k127_1011152_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 583.0
SHD1_k127_1011152_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 462.0
SHD1_k127_1012397_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1073.0
SHD1_k127_1012397_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.269e-207 655.0
SHD1_k127_1012397_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000002265 223.0
SHD1_k127_1012397_11 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000006794 220.0
SHD1_k127_1012397_12 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000000003838 174.0
SHD1_k127_1012397_13 - - - - 0.00000000000000000000000000000000000000001925 164.0
SHD1_k127_1012397_14 - - - - 0.000000000000000000000000000000000000006646 147.0
SHD1_k127_1012397_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000004556 142.0
SHD1_k127_1012397_16 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000002956 146.0
SHD1_k127_1012397_17 DoxX - - - 0.00000000000000000000000000000002004 132.0
SHD1_k127_1012397_18 Predicted membrane protein (DUF2127) - - - 0.00000000000000000000000000000321 128.0
SHD1_k127_1012397_19 - - - - 0.00000000000000000000000000002693 125.0
SHD1_k127_1012397_2 PFAM Alcohol dehydrogenase GroES-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 576.0
SHD1_k127_1012397_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000001114 108.0
SHD1_k127_1012397_22 Sigma-70, region 4 K03088 - - 0.0000000000000000000006154 98.0
SHD1_k127_1012397_24 Pas domain - - - 0.000000000000000005864 91.0
SHD1_k127_1012397_25 - - - - 0.0006314 45.0
SHD1_k127_1012397_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 523.0
SHD1_k127_1012397_4 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 516.0
SHD1_k127_1012397_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 340.0
SHD1_k127_1012397_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 312.0
SHD1_k127_1012397_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
SHD1_k127_1012397_8 Domain of unknown function (DUF1906) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001985 262.0
SHD1_k127_1012397_9 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003524 251.0
SHD1_k127_1014430_0 DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 480.0
SHD1_k127_1014430_1 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000005927 130.0
SHD1_k127_1019001_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 2.198e-262 826.0
SHD1_k127_1019001_1 Beta-Casp domain K07576 - - 1.95e-228 715.0
SHD1_k127_1019001_10 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.000000000000000000000000000000000000000000000000000008794 194.0
SHD1_k127_1019001_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.208e-195 616.0
SHD1_k127_1019001_3 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 458.0
SHD1_k127_1019001_4 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 377.0
SHD1_k127_1019001_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 357.0
SHD1_k127_1019001_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 346.0
SHD1_k127_1019001_7 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302,K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001485 250.0
SHD1_k127_1019001_8 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000781 230.0
SHD1_k127_1019001_9 - - - - 0.000000000000000000000000000000000000000000000000000002083 198.0
SHD1_k127_1019598_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
SHD1_k127_1019598_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
SHD1_k127_1019598_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 338.0
SHD1_k127_1019598_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 302.0
SHD1_k127_1019598_4 regulation of circadian rhythm - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
SHD1_k127_1019598_5 Response regulator, receiver - - - 0.0000000000000000000000000000000004301 139.0
SHD1_k127_1022970_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.721e-263 820.0
SHD1_k127_1022970_1 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.619e-201 642.0
SHD1_k127_1022970_10 OsmC-like protein K04063 - - 0.000000000000003027 81.0
SHD1_k127_1022970_11 Type IV pilus biogenesis stability protein PilW - - - 0.0000008761 60.0
SHD1_k127_1022970_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 563.0
SHD1_k127_1022970_3 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 430.0
SHD1_k127_1022970_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 310.0
SHD1_k127_1022970_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 286.0
SHD1_k127_1022970_6 - - - - 0.0000000000000000000000000000000000000000000000000004017 190.0
SHD1_k127_1022970_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000006516 186.0
SHD1_k127_1022970_8 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000001752 173.0
SHD1_k127_1022970_9 membrane protein (DUF2306) - - - 0.000000000000000000000007626 111.0
SHD1_k127_10352_0 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 621.0
SHD1_k127_10352_1 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 444.0
SHD1_k127_10352_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 344.0
SHD1_k127_10352_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 323.0
SHD1_k127_10352_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000006041 157.0
SHD1_k127_1042455_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1521.0
SHD1_k127_1042455_1 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000000004091 154.0
SHD1_k127_1042455_2 lactoylglutathione lyase activity - - - 0.0000000008426 60.0
SHD1_k127_1044421_0 C-terminal, D2-small domain, of ClpB protein - - - 5.469e-213 666.0
SHD1_k127_1044421_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 445.0
SHD1_k127_1044421_2 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000002585 192.0
SHD1_k127_1064670_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 484.0
SHD1_k127_1064670_1 DNA recombination K09760 - - 0.0000000000000000000000000000000000008948 145.0
SHD1_k127_1064670_2 Protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000005449 135.0
SHD1_k127_1083131_0 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 603.0
SHD1_k127_1083131_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 451.0
SHD1_k127_1083131_10 Putative Ig domain - - - 0.000000000000004247 82.0
SHD1_k127_1083131_2 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 424.0
SHD1_k127_1083131_3 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 375.0
SHD1_k127_1083131_4 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
SHD1_k127_1083131_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000001364 189.0
SHD1_k127_1083131_6 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000000000000000000005826 192.0
SHD1_k127_1083131_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000009575 153.0
SHD1_k127_1083131_8 - - - - 0.000000000000000000000000000000000000001085 160.0
SHD1_k127_1083131_9 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000001068 118.0
SHD1_k127_1092793_0 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000001136 214.0
SHD1_k127_1092793_1 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000002923 183.0
SHD1_k127_1092793_2 - - - - 0.00000000000000000000000000000000006934 141.0
SHD1_k127_1092815_0 ABC transporter - - - 7.462e-261 812.0
SHD1_k127_1092815_1 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 586.0
SHD1_k127_1092815_10 PFAM Phosphoglycerate mutase - - - 0.000000000000000001785 91.0
SHD1_k127_1092815_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 576.0
SHD1_k127_1092815_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 496.0
SHD1_k127_1092815_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 447.0
SHD1_k127_1092815_5 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 375.0
SHD1_k127_1092815_6 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000001342 194.0
SHD1_k127_1092815_7 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000001026 132.0
SHD1_k127_1092815_8 membrane - - - 0.00000000000000000000000002175 115.0
SHD1_k127_1092815_9 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000004776 106.0
SHD1_k127_1138532_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1160.0
SHD1_k127_1138532_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003344 282.0
SHD1_k127_1138532_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004248 275.0
SHD1_k127_1138532_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000153 274.0
SHD1_k127_1138532_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000944 237.0
SHD1_k127_1138532_5 SnoaL-like polyketide cyclase - - - 0.000000000008733 70.0
SHD1_k127_1167859_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 504.0
SHD1_k127_1167859_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 443.0
SHD1_k127_1167859_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 375.0
SHD1_k127_1167859_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 271.0
SHD1_k127_1167859_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000002967 245.0
SHD1_k127_1167859_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000002226 122.0
SHD1_k127_1167859_6 DsrE/DsrF-like family K09004 - - 0.0000000000000135 79.0
SHD1_k127_1186398_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 3.444e-273 847.0
SHD1_k127_1186398_1 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 3.62e-198 633.0
SHD1_k127_1186398_2 Sigma-54 interaction domain - - - 0.00001895 55.0
SHD1_k127_1215384_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.9e-199 623.0
SHD1_k127_1215384_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 392.0
SHD1_k127_1215384_2 - - - - 0.0000000000000000000000000000000000000000000000000003384 201.0
SHD1_k127_1215384_3 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000000000000000001607 154.0
SHD1_k127_1215384_4 YjbR - - - 0.0000000000000000000000000000000000001671 148.0
SHD1_k127_1215384_5 Response regulator, receiver - - - 0.0000000000000000000000000001256 124.0
SHD1_k127_1215384_6 - - - - 0.000000000000002824 77.0
SHD1_k127_1218797_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 7.964e-262 817.0
SHD1_k127_1218797_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.133e-239 754.0
SHD1_k127_1220067_0 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 384.0
SHD1_k127_1220067_1 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 379.0
SHD1_k127_1220067_10 - - - - 0.000000000000001917 77.0
SHD1_k127_1220067_12 Protein of unknown function (DUF1569) - - - 0.000000000002435 74.0
SHD1_k127_1220067_13 TrkA-C domain K10716 - - 0.0000000001483 63.0
SHD1_k127_1220067_14 Phosphoesterase family K21302 - 3.1.3.64 0.0001619 49.0
SHD1_k127_1220067_2 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000001461 265.0
SHD1_k127_1220067_3 - - - - 0.00000000000000000000000000000000000000000000000000000001608 205.0
SHD1_k127_1220067_4 BON domain - - - 0.0000000000000000000000000000000000000000000002504 181.0
SHD1_k127_1220067_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000001145 163.0
SHD1_k127_1220067_6 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000001204 151.0
SHD1_k127_1220067_9 Glycosyl transferase, family 2 - - - 0.00000000000000001285 88.0
SHD1_k127_1223335_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1186.0
SHD1_k127_1223335_1 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
SHD1_k127_1225599_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 238.0
SHD1_k127_1225599_1 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.0000000000000000000000002693 117.0
SHD1_k127_1230896_0 GTP-binding protein TypA K06207 - - 5.102e-240 746.0
SHD1_k127_1246106_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.63e-238 752.0
SHD1_k127_1246106_1 Major facilitator Superfamily K16211 - - 1.61e-196 621.0
SHD1_k127_1246106_2 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 396.0
SHD1_k127_1246106_3 Fumarylacetoacetase N-terminal K01555 - 3.7.1.2 0.00000000000000000000000000000000008913 134.0
SHD1_k127_1255754_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0050218,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 3.896e-306 948.0
SHD1_k127_1255754_1 glycolate transport K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 340.0
SHD1_k127_1256482_0 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 434.0
SHD1_k127_1256482_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000001536 178.0
SHD1_k127_1256482_2 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000006673 139.0
SHD1_k127_1256482_3 Response regulator, receiver - - - 0.00000000000000000000005661 99.0
SHD1_k127_1256482_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000003028 102.0
SHD1_k127_1256482_5 chemotaxis signal transduction protein K03408 - - 0.0000000000000004283 85.0
SHD1_k127_127374_0 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 424.0
SHD1_k127_127374_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 323.0
SHD1_k127_127374_2 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000008431 242.0
SHD1_k127_127374_3 DinB family - - - 0.00000000000000000000000000000000000000000000000001156 186.0
SHD1_k127_127374_4 isomerase activity K01821 - 5.3.2.6 0.00000000000000000000000000009019 117.0
SHD1_k127_127374_5 TonB dependent receptor - - - 0.00001536 55.0
SHD1_k127_1275881_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 496.0
SHD1_k127_1275881_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 401.0
SHD1_k127_1275881_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000002747 206.0
SHD1_k127_1275881_11 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000472 180.0
SHD1_k127_1275881_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000006228 176.0
SHD1_k127_1275881_13 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000008246 172.0
SHD1_k127_1275881_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000002581 175.0
SHD1_k127_1275881_15 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000004452 167.0
SHD1_k127_1275881_16 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000006003 162.0
SHD1_k127_1275881_17 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000001559 128.0
SHD1_k127_1275881_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000001675 121.0
SHD1_k127_1275881_19 Ribosomal protein L30 K02907 - - 0.0000000000000000000000004049 106.0
SHD1_k127_1275881_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 355.0
SHD1_k127_1275881_20 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000004755 101.0
SHD1_k127_1275881_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000003311 83.0
SHD1_k127_1275881_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 335.0
SHD1_k127_1275881_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 319.0
SHD1_k127_1275881_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 286.0
SHD1_k127_1275881_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 282.0
SHD1_k127_1275881_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000354 262.0
SHD1_k127_1275881_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000000005376 213.0
SHD1_k127_1275881_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000007122 205.0
SHD1_k127_1279567_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 441.0
SHD1_k127_1279567_1 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 404.0
SHD1_k127_1279567_2 peroxiredoxin, OsmC subfamily K04063 - - 0.0000000000000000000000000000000000000000000000000001243 188.0
SHD1_k127_1279567_4 - - - - 0.0000000000000000000007656 96.0
SHD1_k127_1279567_5 sh3 domain protein - - - 0.00000000000007856 83.0
SHD1_k127_1283276_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 604.0
SHD1_k127_1283276_1 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 299.0
SHD1_k127_1283276_2 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000000003145 235.0
SHD1_k127_1283276_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
SHD1_k127_1283276_4 Cold shock protein K03704 - - 0.0000000000000000000000000000003992 126.0
SHD1_k127_1283276_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000003384 93.0
SHD1_k127_1291223_0 Chaperone - - - 0.000000001182 68.0
SHD1_k127_1292886_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.965e-261 813.0
SHD1_k127_1292886_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.64e-232 723.0
SHD1_k127_1292886_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001708 262.0
SHD1_k127_1292886_3 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000004231 128.0
SHD1_k127_1292886_4 - - - - 0.000000000000000000000001906 105.0
SHD1_k127_1303679_0 CHASE3 domain - - - 7.167e-317 983.0
SHD1_k127_1303679_1 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 446.0
SHD1_k127_1303679_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 302.0
SHD1_k127_1303679_3 Response regulator, receiver K10819,K20975 - 2.7.13.3 0.0000000000000000000000000000000000000000004102 160.0
SHD1_k127_1303679_4 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000000000000002326 139.0
SHD1_k127_1303679_5 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.0000000000000000000000000000000001368 135.0
SHD1_k127_1303679_6 Gas vesicle protein K - - - 0.00000000000000000005824 89.0
SHD1_k127_1316549_0 signal transduction histidine kinase - - - 6.013e-257 812.0
SHD1_k127_1316549_1 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 1.422e-237 741.0
SHD1_k127_1316549_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 381.0
SHD1_k127_1316549_3 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003524 254.0
SHD1_k127_1316549_4 - - - - 0.000000000000000000000000000000000000000006366 159.0
SHD1_k127_1337377_0 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 399.0
SHD1_k127_1337377_1 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000001018 252.0
SHD1_k127_1363697_0 SpoIVB peptidase S55 - - - 1.425e-231 730.0
SHD1_k127_1363697_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 611.0
SHD1_k127_1363697_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 439.0
SHD1_k127_1374667_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 396.0
SHD1_k127_1387089_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 301.0
SHD1_k127_1387089_1 - - - - 0.000002199 53.0
SHD1_k127_1389268_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 602.0
SHD1_k127_1389268_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 482.0
SHD1_k127_1389268_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000002098 209.0
SHD1_k127_1415994_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 8.282e-243 755.0
SHD1_k127_1415994_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.267e-230 724.0
SHD1_k127_1415994_10 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000008285 55.0
SHD1_k127_1415994_11 CHAD - - - 0.0000001026 58.0
SHD1_k127_1415994_2 Tetratricopeptide repeats K12132 - 2.7.11.1 2.381e-211 679.0
SHD1_k127_1415994_3 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 556.0
SHD1_k127_1415994_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 524.0
SHD1_k127_1415994_5 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 466.0
SHD1_k127_1415994_6 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 422.0
SHD1_k127_1415994_7 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 396.0
SHD1_k127_1415994_8 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
SHD1_k127_1417566_0 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 399.0
SHD1_k127_1417566_1 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 395.0
SHD1_k127_1417566_2 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 341.0
SHD1_k127_1417566_3 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008801 257.0
SHD1_k127_1417566_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000003581 188.0
SHD1_k127_1417566_5 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000004854 116.0
SHD1_k127_1437775_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 6.7e-224 707.0
SHD1_k127_1437775_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 4.385e-215 676.0
SHD1_k127_1437775_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 342.0
SHD1_k127_1437775_3 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001492 222.0
SHD1_k127_1437775_4 D-Tyr-tRNA(Tyr) deacylase K07560 - - 0.00000000000000000000000000000000000000000000000000000000002632 209.0
SHD1_k127_1437775_5 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000002524 173.0
SHD1_k127_1437775_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000001082 116.0
SHD1_k127_1437775_8 lysine biosynthetic process via aminoadipic acid - - - 0.000001435 54.0
SHD1_k127_1439998_0 Involved in the tonB-independent uptake of proteins - - - 7.7e-322 1007.0
SHD1_k127_1439998_1 Involved in the tonB-independent uptake of proteins - - - 2.46e-297 938.0
SHD1_k127_1439998_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 605.0
SHD1_k127_1439998_3 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000008318 196.0
SHD1_k127_1439998_4 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000002608 109.0
SHD1_k127_1442815_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1307.0
SHD1_k127_1442815_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 452.0
SHD1_k127_1442815_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 324.0
SHD1_k127_1442815_3 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 281.0
SHD1_k127_1442815_4 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
SHD1_k127_1442815_5 Thioredoxin-like - - - 0.000000000000000000000000000000000005604 142.0
SHD1_k127_1442815_6 Hfq protein K03666 - - 0.0000000000000000000000000000000002257 135.0
SHD1_k127_1442815_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000000000000000000001464 113.0
SHD1_k127_1464787_0 Radical SAM - - - 0.0 1011.0
SHD1_k127_1464787_1 Rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
SHD1_k127_1464787_2 shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000001212 208.0
SHD1_k127_1464787_3 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000007692 109.0
SHD1_k127_1464787_4 PspC domain K03973 - - 0.0000000000000000000000551 102.0
SHD1_k127_1473292_0 4Fe-4S dicluster domain K00184 - - 5.13e-242 757.0
SHD1_k127_1473292_1 PFAM Polysulphide reductase, NrfD K00185 - - 3.952e-222 696.0
SHD1_k127_1473292_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001182 256.0
SHD1_k127_1473292_3 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004149 238.0
SHD1_k127_1473292_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000008339 52.0
SHD1_k127_1487973_0 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 526.0
SHD1_k127_1487973_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 434.0
SHD1_k127_1487973_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 349.0
SHD1_k127_1487973_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 331.0
SHD1_k127_1487973_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 258.0
SHD1_k127_1487973_5 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003154 253.0
SHD1_k127_1487973_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000174 225.0
SHD1_k127_1487973_7 hydroperoxide reductase activity - - - 0.0000000000000000976 79.0
SHD1_k127_1487973_8 - - - - 0.0000000003092 62.0
SHD1_k127_1488505_0 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 295.0
SHD1_k127_1488505_1 TOBE domain K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000002367 272.0
SHD1_k127_1488505_2 Molybdate ABC transporter substrate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000005733 209.0
SHD1_k127_1488505_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000005856 127.0
SHD1_k127_1488505_5 AsmA family K07289 - - 0.0000000000000000000000000008651 123.0
SHD1_k127_1489127_0 ABC transporter K11085 - - 1.39e-253 796.0
SHD1_k127_1489127_1 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
SHD1_k127_1498962_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.819e-196 619.0
SHD1_k127_1498962_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 357.0
SHD1_k127_1498962_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
SHD1_k127_1498962_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000002911 228.0
SHD1_k127_1498962_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000002117 204.0
SHD1_k127_1498962_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000008734 141.0
SHD1_k127_1498962_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000004082 99.0
SHD1_k127_1498962_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001639 74.0
SHD1_k127_1499084_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 550.0
SHD1_k127_1499084_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 448.0
SHD1_k127_1499084_10 Rubrerythrin - - - 0.00000000000000000000000000000003071 131.0
SHD1_k127_1499084_11 PQ loop repeat K15383 - - 0.00000000000000000000000005572 109.0
SHD1_k127_1499084_13 Pkd domain containing protein K20276 - - 0.0003447 52.0
SHD1_k127_1499084_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 334.0
SHD1_k127_1499084_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 328.0
SHD1_k127_1499084_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
SHD1_k127_1499084_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000001813 203.0
SHD1_k127_1499084_6 Cupin domain - - - 0.00000000000000000000000000000000000000000000006793 171.0
SHD1_k127_1499084_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000001212 166.0
SHD1_k127_1499084_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000116 148.0
SHD1_k127_1499084_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000008991 139.0
SHD1_k127_1501991_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 4.058e-194 614.0
SHD1_k127_1501991_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 524.0
SHD1_k127_1501991_2 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000003634 97.0
SHD1_k127_1501991_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000003099 79.0
SHD1_k127_1501991_4 phosphorelay signal transduction system - - - 0.00000002256 58.0
SHD1_k127_1504074_0 Phospholipase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 479.0
SHD1_k127_1504074_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 352.0
SHD1_k127_1504074_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000005206 49.0
SHD1_k127_1514163_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 336.0
SHD1_k127_1514163_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 330.0
SHD1_k127_1514163_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000007536 191.0
SHD1_k127_1514163_3 Dehydrogenase E1 component - - - 0.0002936 53.0
SHD1_k127_1517281_0 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 466.0
SHD1_k127_1517281_1 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 427.0
SHD1_k127_1517281_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 369.0
SHD1_k127_1517281_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K07003 - - 0.000000000000000000000000000000000000000000000000000000000000001184 226.0
SHD1_k127_1517281_4 thiolester hydrolase activity K07000 - - 0.0000000000000000000000000000000000000000000000001263 199.0
SHD1_k127_1542659_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.093e-205 642.0
SHD1_k127_1542659_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001817 284.0
SHD1_k127_1576663_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 554.0
SHD1_k127_1576663_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 528.0
SHD1_k127_1576663_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 472.0
SHD1_k127_1576663_3 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
SHD1_k127_1576663_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005254 256.0
SHD1_k127_1576663_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004668 215.0
SHD1_k127_1576663_6 - - - - 0.00000000000000000000000000000002434 130.0
SHD1_k127_1576663_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000006173 111.0
SHD1_k127_1590311_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 430.0
SHD1_k127_1590311_1 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 319.0
SHD1_k127_1590311_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 316.0
SHD1_k127_1590311_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004508 266.0
SHD1_k127_1590311_4 - - - - 0.0000000000000002066 87.0
SHD1_k127_1590311_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000009226 53.0
SHD1_k127_1609412_0 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 602.0
SHD1_k127_1609412_1 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 526.0
SHD1_k127_1609412_2 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000004658 126.0
SHD1_k127_1609412_3 response regulator, receiver - - - 0.0000000000000000000000004311 111.0
SHD1_k127_1609412_4 - - - - 0.000952 47.0
SHD1_k127_1615276_0 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 550.0
SHD1_k127_1615276_1 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 486.0
SHD1_k127_1615276_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 383.0
SHD1_k127_1615276_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000728 179.0
SHD1_k127_1615276_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000001587 141.0
SHD1_k127_1615276_5 PFAM Chlorite dismutase - - - 0.000000000000000000006397 98.0
SHD1_k127_1649413_0 Ftsk_gamma K03466 - - 4.341e-295 925.0
SHD1_k127_1649413_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 407.0
SHD1_k127_1649413_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 342.0
SHD1_k127_1649413_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003138 237.0
SHD1_k127_1649413_4 EamA-like transporter family - - - 0.0000000000000000000000000456 119.0
SHD1_k127_1649413_5 PepSY-associated TM region - - - 0.00000000000000242 82.0
SHD1_k127_1650863_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 539.0
SHD1_k127_1650863_1 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 418.0
SHD1_k127_1650863_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001812 219.0
SHD1_k127_1650863_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000003044 169.0
SHD1_k127_1650863_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001012 137.0
SHD1_k127_1650863_5 Belongs to the universal stress protein A family - - - 0.0000000000000000000001252 109.0
SHD1_k127_1660445_0 peptidyl-tyrosine sulfation - - - 0.0 1544.0
SHD1_k127_1660445_1 Vault protein inter-alpha-trypsin domain K07114 - - 7.538e-288 904.0
SHD1_k127_1660445_2 - K19693 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 478.0
SHD1_k127_1676311_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.059e-266 838.0
SHD1_k127_1676311_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 332.0
SHD1_k127_1682766_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 583.0
SHD1_k127_1682766_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 345.0
SHD1_k127_1682766_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 298.0
SHD1_k127_1682766_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000002291 139.0
SHD1_k127_1682766_4 Putative adhesin - - - 0.000000000000000000000000000000002857 140.0
SHD1_k127_1682766_5 - - - - 0.000000003721 66.0
SHD1_k127_1705511_0 PFAM peptidase M28 - - - 1.081e-200 640.0
SHD1_k127_1705511_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000003571 199.0
SHD1_k127_1705511_2 - - - - 0.000000000000006788 85.0
SHD1_k127_1716817_0 sulfuric ester hydrolase activity K03760,K06349,K19353 GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 518.0
SHD1_k127_1716817_1 - - - - 0.000000000000000000000000000000008485 134.0
SHD1_k127_1716817_2 Regulatory protein - - - 0.00000000000000000000000000000009932 126.0
SHD1_k127_1716817_3 Glycosyl transferase family group 2 K16557 - - 0.0000000000000000000000000006572 126.0
SHD1_k127_1737914_0 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 319.0
SHD1_k127_1737914_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 309.0
SHD1_k127_1737914_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000004514 260.0
SHD1_k127_1737914_3 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000004474 232.0
SHD1_k127_1737914_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000006934 168.0
SHD1_k127_175221_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 503.0
SHD1_k127_175221_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000001277 202.0
SHD1_k127_175221_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000007923 113.0
SHD1_k127_175221_3 PFAM Septum formation initiator K05589 - - 0.000000000000000000003708 96.0
SHD1_k127_175221_4 - - - - 0.000000000000000000009167 95.0
SHD1_k127_1762331_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.45e-220 691.0
SHD1_k127_1762331_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.245e-199 634.0
SHD1_k127_1762331_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 311.0
SHD1_k127_1762331_11 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007167 278.0
SHD1_k127_1762331_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003386 280.0
SHD1_k127_1762331_14 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000004587 217.0
SHD1_k127_1762331_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000003179 214.0
SHD1_k127_1762331_16 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000002088 210.0
SHD1_k127_1762331_17 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001785 195.0
SHD1_k127_1762331_18 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000567 185.0
SHD1_k127_1762331_19 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000006033 171.0
SHD1_k127_1762331_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 578.0
SHD1_k127_1762331_20 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000002118 156.0
SHD1_k127_1762331_21 Peptidase M56 - - - 0.000000000000000000000000000000001826 135.0
SHD1_k127_1762331_22 Protein of unknown function (DUF2905) - - - 0.0000000000000000000002867 99.0
SHD1_k127_1762331_23 protein histidine kinase activity K07651,K07711 - 2.7.13.3 0.000000000000006369 82.0
SHD1_k127_1762331_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 567.0
SHD1_k127_1762331_4 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 542.0
SHD1_k127_1762331_5 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 509.0
SHD1_k127_1762331_6 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 416.0
SHD1_k127_1762331_7 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 406.0
SHD1_k127_1762331_8 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 364.0
SHD1_k127_1762331_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 342.0
SHD1_k127_1772853_0 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000003014 134.0
SHD1_k127_1772853_1 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000001036 101.0
SHD1_k127_1772853_2 PFAM von Willebrand factor type A - - - 0.00000000000000000004458 102.0
SHD1_k127_1772853_3 PhoH-like protein K06217 - - 0.00004342 47.0
SHD1_k127_1779157_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
SHD1_k127_1779157_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005991 248.0
SHD1_k127_1779157_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000002264 213.0
SHD1_k127_1780832_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.503e-213 672.0
SHD1_k127_1780832_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 625.0
SHD1_k127_1780832_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000007047 202.0
SHD1_k127_1780832_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000004637 145.0
SHD1_k127_1780832_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 592.0
SHD1_k127_1780832_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 506.0
SHD1_k127_1780832_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 461.0
SHD1_k127_1780832_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 347.0
SHD1_k127_1780832_6 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 326.0
SHD1_k127_1780832_7 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 295.0
SHD1_k127_1780832_8 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 273.0
SHD1_k127_1780832_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
SHD1_k127_1800725_0 Permease, YjgP YjgQ - - - 0.0 1044.0
SHD1_k127_1800725_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 4.904e-210 667.0
SHD1_k127_1800725_2 PFAM Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 465.0
SHD1_k127_1800725_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 313.0
SHD1_k127_1800725_4 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 288.0
SHD1_k127_1800725_5 Glycosyl hydrolase family 57 - - - 0.000000000000000000000009769 102.0
SHD1_k127_183730_0 Protein tyrosine kinase - - - 1.665e-225 721.0
SHD1_k127_183730_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 350.0
SHD1_k127_1845808_0 COG0515 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 475.0
SHD1_k127_1845808_1 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005646 258.0
SHD1_k127_1845808_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000003729 138.0
SHD1_k127_1845808_3 LysM domain - - - 0.0000000000000098 83.0
SHD1_k127_1845808_4 Forkhead associated domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00005912 55.0
SHD1_k127_185519_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 424.0
SHD1_k127_185519_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 383.0
SHD1_k127_185519_2 - - - - 0.0000000000000000000000000000000000000000000001223 171.0
SHD1_k127_185519_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000001199 164.0
SHD1_k127_185519_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000292 130.0
SHD1_k127_185519_5 Cupin domain - - - 0.000000000000000000000000000009585 117.0
SHD1_k127_185519_6 - - - - 0.00000000000000000002221 101.0
SHD1_k127_1865748_0 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 433.0
SHD1_k127_1865748_1 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 361.0
SHD1_k127_1865748_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 357.0
SHD1_k127_1865748_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006187 285.0
SHD1_k127_1865748_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000001699 146.0
SHD1_k127_1865748_5 Sporulation and spore germination - - - 0.000000000000000000000000000000000004197 147.0
SHD1_k127_1865748_6 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000003694 62.0
SHD1_k127_1866110_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 554.0
SHD1_k127_1866110_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 459.0
SHD1_k127_1866110_2 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 346.0
SHD1_k127_1866110_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 340.0
SHD1_k127_1866110_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 328.0
SHD1_k127_1866110_5 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000001966 243.0
SHD1_k127_1866110_6 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
SHD1_k127_1866110_7 integral membrane protein - - - 0.000000000000000002779 94.0
SHD1_k127_1866110_8 PFAM Amidase - - - 0.0003443 44.0
SHD1_k127_1893070_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 525.0
SHD1_k127_1893070_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
SHD1_k127_1893070_2 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000004459 186.0
SHD1_k127_1915051_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 499.0
SHD1_k127_1915051_1 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000002733 237.0
SHD1_k127_1915051_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000224 134.0
SHD1_k127_1915051_3 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.000000000000000001016 86.0
SHD1_k127_1923513_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 465.0
SHD1_k127_1923513_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 358.0
SHD1_k127_1923513_2 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
SHD1_k127_1923513_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000845 199.0
SHD1_k127_1923513_4 Putative zinc-finger - - - 0.000000000006308 70.0
SHD1_k127_1938424_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 345.0
SHD1_k127_1938424_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000001736 113.0
SHD1_k127_1938424_2 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.000000000000000000001022 97.0
SHD1_k127_1938424_3 protein transport across the cell outer membrane K02453 - - 0.00000000001428 73.0
SHD1_k127_1940877_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 321.0
SHD1_k127_1940877_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000007626 164.0
SHD1_k127_1940877_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 0.000000000000001448 76.0
SHD1_k127_1951699_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 355.0
SHD1_k127_1951699_1 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000005265 152.0
SHD1_k127_1951699_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000002513 99.0
SHD1_k127_195572_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 4.48e-294 915.0
SHD1_k127_195572_1 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 508.0
SHD1_k127_195572_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 315.0
SHD1_k127_195572_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000001249 89.0
SHD1_k127_1956699_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 438.0
SHD1_k127_1956699_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008997 280.0
SHD1_k127_1956699_2 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000002368 221.0
SHD1_k127_1956699_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000001737 207.0
SHD1_k127_1963676_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 621.0
SHD1_k127_1963676_1 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000004877 66.0
SHD1_k127_1967480_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.0 1040.0
SHD1_k127_1967480_1 Rhodanese-like domain K01069 - 3.1.2.6 4.965e-236 736.0
SHD1_k127_1967480_10 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000001697 146.0
SHD1_k127_1967480_11 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000006131 107.0
SHD1_k127_1967480_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 450.0
SHD1_k127_1967480_3 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 345.0
SHD1_k127_1967480_4 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 347.0
SHD1_k127_1967480_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 351.0
SHD1_k127_1967480_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 320.0
SHD1_k127_1967480_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003108 280.0
SHD1_k127_1967480_8 - - - - 0.000000000000000000000000000000000000000000000000009973 186.0
SHD1_k127_1967480_9 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000002439 178.0
SHD1_k127_1972876_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 387.0
SHD1_k127_1972876_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
SHD1_k127_1972876_2 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.00000000000000000003894 100.0
SHD1_k127_1980254_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 476.0
SHD1_k127_1980254_2 DUF218 domain K03748 - - 0.000000000000000000000000000000000000000000000000000000002029 208.0
SHD1_k127_1980254_3 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000003387 205.0
SHD1_k127_1980254_4 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000001734 175.0
SHD1_k127_1980254_7 Bacterial regulatory proteins, tetR family - - - 0.0000008413 57.0
SHD1_k127_1992668_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 445.0
SHD1_k127_1992668_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 269.0
SHD1_k127_1992668_10 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000002532 91.0
SHD1_k127_1992668_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000001523 69.0
SHD1_k127_1992668_2 Bifunctional protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001379 243.0
SHD1_k127_1992668_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000005198 235.0
SHD1_k127_1992668_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000158 181.0
SHD1_k127_1992668_5 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000007811 173.0
SHD1_k127_1992668_6 - - - - 0.0000000000000000000000000000000000000000001619 168.0
SHD1_k127_1992668_7 hyperosmotic response - - - 0.000000000000000000000000000000000000000006588 160.0
SHD1_k127_1992668_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000002791 115.0
SHD1_k127_1992668_9 - - - - 0.00000000000000000009411 102.0
SHD1_k127_1999862_0 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 455.0
SHD1_k127_1999862_1 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 419.0
SHD1_k127_1999862_2 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 392.0
SHD1_k127_1999862_3 PFAM glycosyl transferase family 39 - - - 0.00000000004232 64.0
SHD1_k127_2012325_0 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 8.823e-224 703.0
SHD1_k127_2012325_1 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 522.0
SHD1_k127_2012325_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 383.0
SHD1_k127_2012325_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 330.0
SHD1_k127_2012325_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000229 260.0
SHD1_k127_2012325_5 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000008994 208.0
SHD1_k127_2012325_6 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000005704 159.0
SHD1_k127_2012325_7 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000000000007428 155.0
SHD1_k127_2020997_0 DEAD DEAH box helicase K03724 - - 0.0 2188.0
SHD1_k127_2020997_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 2.077e-222 692.0
SHD1_k127_2020997_2 Belongs to the FPG family K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 366.0
SHD1_k127_2020997_3 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000002029 216.0
SHD1_k127_2020997_4 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000004254 198.0
SHD1_k127_2020997_5 Glycosyl hydrolase family 63 C-terminal domain - - - 0.00000000000000000000000000000000000005144 149.0
SHD1_k127_2020997_6 Cold shock protein K03704 - - 0.00000000000000000000000000000002513 126.0
SHD1_k127_2020997_7 - - - - 0.0000000000000000000000000003727 118.0
SHD1_k127_2020997_8 Response regulator, receiver - - - 0.000000000000000000000004865 108.0
SHD1_k127_202141_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 2.829e-263 828.0
SHD1_k127_202141_1 Lamin Tail Domain K07004 - - 2.414e-207 686.0
SHD1_k127_202141_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 528.0
SHD1_k127_202141_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 409.0
SHD1_k127_202141_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000008475 179.0
SHD1_k127_205948_0 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 329.0
SHD1_k127_205948_1 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004223 273.0
SHD1_k127_205948_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000087 261.0
SHD1_k127_205948_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000004276 141.0
SHD1_k127_2072080_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 359.0
SHD1_k127_2072080_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000002371 197.0
SHD1_k127_2072080_2 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000967 119.0
SHD1_k127_2072251_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 2.431e-227 710.0
SHD1_k127_2072251_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 595.0
SHD1_k127_2072251_10 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000002084 67.0
SHD1_k127_2072251_11 - - - - 0.00000000001327 70.0
SHD1_k127_2072251_2 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 562.0
SHD1_k127_2072251_3 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 493.0
SHD1_k127_2072251_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 437.0
SHD1_k127_2072251_5 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003022 239.0
SHD1_k127_2072251_6 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000184 231.0
SHD1_k127_2072251_7 sequence-specific DNA binding - - - 0.0000000000000000000000000000274 128.0
SHD1_k127_2072251_8 chaperone-mediated protein folding - - - 0.0000000000000000000001099 101.0
SHD1_k127_2072251_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000116 100.0
SHD1_k127_2078355_0 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 6.59e-218 687.0
SHD1_k127_2078355_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 547.0
SHD1_k127_2078355_2 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 501.0
SHD1_k127_2078355_3 TIGRFAM Malto-oligosyltrehalose synthase K06044 - 5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 348.0
SHD1_k127_2078355_4 homoserine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000002463 209.0
SHD1_k127_2079711_0 amino acid K03294 - - 6.662e-253 787.0
SHD1_k127_2079711_1 amino acid K03294 - - 1.22e-233 734.0
SHD1_k127_2079711_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000005875 215.0
SHD1_k127_2079711_3 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000001883 190.0
SHD1_k127_2079711_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000001734 118.0
SHD1_k127_208546_0 Receptor family ligand binding region - - - 1.715e-210 670.0
SHD1_k127_208546_1 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.000000000000000001335 85.0
SHD1_k127_2091950_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 468.0
SHD1_k127_2091950_1 SMART cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
SHD1_k127_2097809_0 Manganese containing catalase K07217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 458.0
SHD1_k127_2097809_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 454.0
SHD1_k127_2097809_2 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000002145 146.0
SHD1_k127_2097809_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000003394 138.0
SHD1_k127_2097809_4 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000001359 67.0
SHD1_k127_2104632_0 PFAM Alcohol dehydrogenase K12957,K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 616.0
SHD1_k127_2104632_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 493.0
SHD1_k127_2104632_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 434.0
SHD1_k127_2104632_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000002689 151.0
SHD1_k127_210655_0 B12 binding domain - - - 2.336e-270 838.0
SHD1_k127_210655_1 B12 binding domain - - - 7.294e-245 765.0
SHD1_k127_210655_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000003352 81.0
SHD1_k127_210655_2 B12 binding domain - - - 7.3e-212 666.0
SHD1_k127_210655_3 radical SAM domain protein - - - 7.324e-195 623.0
SHD1_k127_210655_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 579.0
SHD1_k127_210655_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 466.0
SHD1_k127_210655_6 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 338.0
SHD1_k127_210655_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007269 279.0
SHD1_k127_210655_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002135 238.0
SHD1_k127_210655_9 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000000000001939 212.0
SHD1_k127_2106628_0 TIGRFAM luciferase family oxidoreductase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 486.0
SHD1_k127_2106628_1 region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 271.0
SHD1_k127_2106628_3 - - - - 0.000000000000000000000000000000000003375 139.0
SHD1_k127_2106628_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000006543 135.0
SHD1_k127_2106628_5 COG0768 cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000003521 64.0
SHD1_k127_2116112_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0 1127.0
SHD1_k127_2116112_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 503.0
SHD1_k127_2116112_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 448.0
SHD1_k127_2116112_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 427.0
SHD1_k127_2116112_4 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000000000000000000000000003074 134.0
SHD1_k127_2153989_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 510.0
SHD1_k127_2153989_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 480.0
SHD1_k127_2153989_2 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 425.0
SHD1_k127_2153989_3 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000002541 225.0
SHD1_k127_2153989_4 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000000000000000000000001284 174.0
SHD1_k127_2179119_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.332e-205 649.0
SHD1_k127_2179119_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 601.0
SHD1_k127_2179119_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 558.0
SHD1_k127_2179119_3 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 335.0
SHD1_k127_2179119_4 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000001341 199.0
SHD1_k127_2179119_5 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000004257 173.0
SHD1_k127_2179119_6 - - - - 0.0000000000000000000000000000000000000000001229 165.0
SHD1_k127_2179119_7 DoxX-like family - - - 0.00000000000000000000000000113 116.0
SHD1_k127_2179119_8 response to antibiotic - - - 0.00000000000000000000000002505 123.0
SHD1_k127_2179119_9 response regulator, receiver - - - 0.00000000000000000000001566 105.0
SHD1_k127_2179195_0 Cytochrome b subunit of the bc K00412,K02635 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
SHD1_k127_2179195_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005324 289.0
SHD1_k127_2179195_2 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000003544 115.0
SHD1_k127_2179195_3 Cytochrome c K17223 - - 0.000005759 57.0
SHD1_k127_2183178_0 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 379.0
SHD1_k127_2183178_1 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 286.0
SHD1_k127_2183178_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005185 287.0
SHD1_k127_2185739_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 1.844e-309 964.0
SHD1_k127_2185739_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 523.0
SHD1_k127_2185739_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 488.0
SHD1_k127_2185739_3 PFAM alpha beta hydrolase K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 433.0
SHD1_k127_2185739_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 331.0
SHD1_k127_2185739_5 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 318.0
SHD1_k127_2185739_6 Glutathione peroxidase K02199 - - 0.000000000000000000000000000000008341 130.0
SHD1_k127_2185739_7 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.0000000000000000000000000000116 122.0
SHD1_k127_2185739_8 PASTA domain K12132 - 2.7.11.1 0.000000000000000003056 86.0
SHD1_k127_2187129_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000002224 198.0
SHD1_k127_2190159_0 AcrB/AcrD/AcrF family - - - 0.0 1099.0
SHD1_k127_2190159_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000007074 176.0
SHD1_k127_2190159_3 regulation of methylation-dependent chromatin silencing K07454 - - 0.00007439 46.0
SHD1_k127_2193926_0 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 594.0
SHD1_k127_2193926_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 576.0
SHD1_k127_2193926_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 437.0
SHD1_k127_2193926_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 424.0
SHD1_k127_2193926_4 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 414.0
SHD1_k127_2193926_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
SHD1_k127_2193926_6 domain, Protein K02450,K07126,K15539 - - 0.0000000000000000000000000000000000000001671 169.0
SHD1_k127_2193926_7 Low affinity iron permease - - - 0.00000000000000000000000000000000000001356 149.0
SHD1_k127_2193926_8 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000002671 109.0
SHD1_k127_2203936_0 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 548.0
SHD1_k127_2203936_1 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 513.0
SHD1_k127_2203936_12 - - - - 0.00000000000003073 81.0
SHD1_k127_2203936_13 Transposase (IS116 IS110 IS902 family) K07486 - - 0.00000000000004236 83.0
SHD1_k127_2203936_14 Domain of unknown function (DUF305) - - - 0.0000000002851 72.0
SHD1_k127_2203936_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 412.0
SHD1_k127_2203936_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
SHD1_k127_2203936_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 355.0
SHD1_k127_2203936_5 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
SHD1_k127_2203936_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001203 276.0
SHD1_k127_2203936_7 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001613 247.0
SHD1_k127_2203936_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004064 256.0
SHD1_k127_2203936_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000008821 96.0
SHD1_k127_2207828_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.62e-218 680.0
SHD1_k127_2207828_1 diguanylate cyclase - - - 1.327e-198 621.0
SHD1_k127_2207828_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006331 241.0
SHD1_k127_2207828_3 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000001233 173.0
SHD1_k127_2207828_4 Helix-turn-helix domain - - - 0.000000000000000000000000000000000001607 151.0
SHD1_k127_2207828_6 - - - - 0.0000004084 53.0
SHD1_k127_2207828_7 Transcriptional regulator - - - 0.000002271 54.0
SHD1_k127_2218064_0 Belongs to the ClpA ClpB family K03696 - - 5.997e-232 736.0
SHD1_k127_2218064_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 563.0
SHD1_k127_2218064_2 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 340.0
SHD1_k127_2218064_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 310.0
SHD1_k127_2218064_4 methyltransferase activity K00587 - 2.1.1.100 0.00000000000000000000000000000001618 134.0
SHD1_k127_2226288_0 PFAM HypF finger K04656 - - 1.437e-299 939.0
SHD1_k127_2226288_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 555.0
SHD1_k127_2226288_2 carbon dioxide binding K04653 - - 0.00000000000000000000009663 109.0
SHD1_k127_2249967_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 540.0
SHD1_k127_2249967_1 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 440.0
SHD1_k127_2249967_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 409.0
SHD1_k127_2249967_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
SHD1_k127_2249967_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 312.0
SHD1_k127_2249967_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
SHD1_k127_2249967_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000151 239.0
SHD1_k127_2249967_7 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000003808 227.0
SHD1_k127_2249967_8 Tetratricopeptide repeat - - - 0.00000000000000000000000006279 121.0
SHD1_k127_2252688_0 Amino acid permease - - - 1.486e-309 965.0
SHD1_k127_2252688_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.383e-249 778.0
SHD1_k127_2252688_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
SHD1_k127_2252688_11 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002073 286.0
SHD1_k127_2252688_12 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000001041 229.0
SHD1_k127_2252688_13 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000001591 162.0
SHD1_k127_2252688_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000002479 150.0
SHD1_k127_2252688_15 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000003743 136.0
SHD1_k127_2252688_16 GAF domain - - - 0.0000000000000000000006689 102.0
SHD1_k127_2252688_17 translation initiation factor activity K06996 - - 0.00000000000000425 80.0
SHD1_k127_2252688_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
SHD1_k127_2252688_3 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 532.0
SHD1_k127_2252688_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 500.0
SHD1_k127_2252688_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 424.0
SHD1_k127_2252688_6 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 364.0
SHD1_k127_2252688_7 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 362.0
SHD1_k127_2252688_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 335.0
SHD1_k127_2252688_9 efflux protein, MATE family K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 345.0
SHD1_k127_2258679_0 ResB-like family K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 289.0
SHD1_k127_2258679_1 Protein involved in outer membrane biogenesis K07289,K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001411 264.0
SHD1_k127_2258679_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001094 239.0
SHD1_k127_2258679_3 Tetratricopeptide repeat - - - 0.0000000000000000000001032 106.0
SHD1_k127_2258679_4 PFAM von Willebrand factor type A - - - 0.0000000000001394 79.0
SHD1_k127_2258679_5 PFAM von Willebrand factor type A - - - 0.00000000000101 76.0
SHD1_k127_2266583_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 357.0
SHD1_k127_2266583_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 301.0
SHD1_k127_2266583_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000002089 184.0
SHD1_k127_226779_0 Alpha/beta hydrolase family - - - 6.859e-309 962.0
SHD1_k127_226779_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 518.0
SHD1_k127_226779_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 347.0
SHD1_k127_2270896_0 PFAM Type II secretion system protein E K02652 - - 9.103e-231 717.0
SHD1_k127_2270896_1 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000512 250.0
SHD1_k127_2270896_2 - - - - 0.00000000000000000000000000000000000000000000000000001866 200.0
SHD1_k127_2270896_3 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000006924 148.0
SHD1_k127_2270896_4 - - - - 0.00000000000000000000000000001582 124.0
SHD1_k127_2270896_5 Belongs to the HesB IscA family - - - 0.000000000000000000001517 94.0
SHD1_k127_2270896_6 - K02664 - - 0.0000000005824 68.0
SHD1_k127_2274785_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 542.0
SHD1_k127_2274785_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
SHD1_k127_2274785_2 Domain of unknown function (DUF1330) - - - 0.000000000000000000000003589 104.0
SHD1_k127_2274785_3 - - - - 0.000000002387 62.0
SHD1_k127_2281729_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 341.0
SHD1_k127_2281729_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000002235 191.0
SHD1_k127_2297752_0 Domain of unknown function (DUF4968) K01811 - 3.2.1.177 2.3e-287 890.0
SHD1_k127_2297752_1 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 527.0
SHD1_k127_2297752_2 Pfam:DUF303 K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 528.0
SHD1_k127_2300994_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 499.0
SHD1_k127_2300994_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 295.0
SHD1_k127_2300994_2 - - - - 0.000000000000004601 78.0
SHD1_k127_2309616_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 608.0
SHD1_k127_2309616_1 Stage II sporulation protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 319.0
SHD1_k127_2309616_2 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001416 183.0
SHD1_k127_2309616_3 PFAM Sulphate transporter antisigma-factor antagonist STAS K17762 - - 0.00000000000000000000000000000000000000000000000001762 182.0
SHD1_k127_2309616_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000002871 70.0
SHD1_k127_2314519_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 589.0
SHD1_k127_2314519_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007265 278.0
SHD1_k127_2314519_2 Peptidase M56 - - - 0.000000000000000000000000000000000000001561 163.0
SHD1_k127_2320660_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 1.228e-212 674.0
SHD1_k127_2320660_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 558.0
SHD1_k127_2320660_2 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 405.0
SHD1_k127_2320660_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000002142 221.0
SHD1_k127_2320660_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000261 191.0
SHD1_k127_2320660_5 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000004045 183.0
SHD1_k127_2320660_6 cellulose binding - - - 0.000000000000000000000000000000002405 142.0
SHD1_k127_2320660_7 Carboxypeptidase regulatory-like domain - - - 0.000000000000000001928 101.0
SHD1_k127_2320660_8 Domain of unknown function (DUF362) - - - 0.000000000000000003852 86.0
SHD1_k127_2320660_9 Recombinase zinc beta ribbon domain - - - 0.00002618 48.0
SHD1_k127_2322080_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 320.0
SHD1_k127_2322080_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 291.0
SHD1_k127_2322080_2 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000007418 156.0
SHD1_k127_2327156_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 1.519e-210 664.0
SHD1_k127_2327156_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 386.0
SHD1_k127_2327156_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003235 207.0
SHD1_k127_2327156_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000001707 203.0
SHD1_k127_2327156_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000005053 169.0
SHD1_k127_2327156_5 Membrane - - - 0.00000000000000000000000000000006508 130.0
SHD1_k127_2327156_7 SnoaL-like domain - - - 0.00004392 51.0
SHD1_k127_2330508_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 454.0
SHD1_k127_2330508_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 334.0
SHD1_k127_2330508_2 - - - - 0.0000000000000000000000000001983 119.0
SHD1_k127_2339153_0 Bacterial regulatory protein, Fis family - - - 3.012e-235 737.0
SHD1_k127_2339153_1 Gas vesicle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 299.0
SHD1_k127_2339153_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000009186 210.0
SHD1_k127_2344317_0 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 361.0
SHD1_k127_2344317_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 345.0
SHD1_k127_2344317_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 323.0
SHD1_k127_2344317_3 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007938 282.0
SHD1_k127_2344317_4 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000000000000431 169.0
SHD1_k127_2344317_5 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000000009344 156.0
SHD1_k127_2344317_6 Hfq protein - - - 0.000000000000000000000000000000000000009939 149.0
SHD1_k127_2344317_7 - - - - 0.000003882 58.0
SHD1_k127_2345877_0 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
SHD1_k127_2345877_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 385.0
SHD1_k127_2345877_2 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 353.0
SHD1_k127_2345877_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000235 137.0
SHD1_k127_2345877_5 - - - - 0.000000000000000000004939 96.0
SHD1_k127_2347930_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 575.0
SHD1_k127_2347930_1 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 526.0
SHD1_k127_2347930_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 501.0
SHD1_k127_2347930_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000009425 172.0
SHD1_k127_2350586_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 466.0
SHD1_k127_2350586_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 319.0
SHD1_k127_2350586_2 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 292.0
SHD1_k127_2350586_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000007077 216.0
SHD1_k127_2350586_4 YCII-related domain K09780 - - 0.00000000000000000000000000004167 126.0
SHD1_k127_2350586_5 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000011 115.0
SHD1_k127_2350586_6 - - - - 0.000000000000000000000004565 108.0
SHD1_k127_2350586_7 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000001443 100.0
SHD1_k127_2350853_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 623.0
SHD1_k127_2350853_1 Tetratricopeptide repeat - - - 0.00000000000008009 76.0
SHD1_k127_2350853_2 - - - - 0.0002033 49.0
SHD1_k127_2350853_3 MOSC N-terminal beta barrel domain K07140 - - 0.0003504 43.0
SHD1_k127_2355119_0 PFAM Glycosyl transferase family 2 - - - 1.934e-260 808.0
SHD1_k127_2355119_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000002307 198.0
SHD1_k127_2355119_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000004215 73.0
SHD1_k127_2389500_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 361.0
SHD1_k127_2389500_1 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000001152 214.0
SHD1_k127_2389500_2 Pseudouridine synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000002371 156.0
SHD1_k127_2389500_3 Domain of unknown function (DUF378) - - - 0.0000000001445 65.0
SHD1_k127_2395970_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.385e-239 742.0
SHD1_k127_2395970_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000006633 190.0
SHD1_k127_2408768_0 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 525.0
SHD1_k127_2408768_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008019 275.0
SHD1_k127_2408768_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002289 207.0
SHD1_k127_2448219_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 588.0
SHD1_k127_2448219_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 484.0
SHD1_k127_2448219_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 424.0
SHD1_k127_2448219_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 392.0
SHD1_k127_2448219_4 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004158 269.0
SHD1_k127_2448219_5 transferase activity, transferring acyl groups K03824,K15520 - 2.3.1.189 0.000000000000000000000000000000006534 132.0
SHD1_k127_2448219_6 - - - - 0.0000000005323 64.0
SHD1_k127_246769_0 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 546.0
SHD1_k127_246769_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 479.0
SHD1_k127_246769_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 457.0
SHD1_k127_246769_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 367.0
SHD1_k127_246769_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
SHD1_k127_246769_5 Belongs to the uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000001526 194.0
SHD1_k127_2471141_0 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000051 78.0
SHD1_k127_2471141_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000002694 64.0
SHD1_k127_2471648_0 GGDEF domain K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 310.0
SHD1_k127_2471648_2 YCII-related domain - - - 0.000000000000000004513 93.0
SHD1_k127_2471648_3 Tetratricopeptide repeat - - - 0.000000837 62.0
SHD1_k127_2471648_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000006036 55.0
SHD1_k127_2471690_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.339e-295 928.0
SHD1_k127_2471690_1 Universal stress protein - - - 0.00000000000000000000000000000000000000000000003678 179.0
SHD1_k127_2471690_2 Universal stress protein - - - 0.000000000000000000006171 98.0
SHD1_k127_2471690_3 - - - - 0.00000223 53.0
SHD1_k127_2472059_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1307.0
SHD1_k127_2472059_1 Ami_3 K01448 - 3.5.1.28 1.272e-230 736.0
SHD1_k127_2472059_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 521.0
SHD1_k127_2472059_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 522.0
SHD1_k127_2472059_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 479.0
SHD1_k127_2472059_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 448.0
SHD1_k127_2472059_6 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
SHD1_k127_2472059_7 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003799 250.0
SHD1_k127_2472059_8 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000009504 161.0
SHD1_k127_2504842_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1088.0
SHD1_k127_2504842_1 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 439.0
SHD1_k127_2504842_2 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
SHD1_k127_2504842_3 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000001109 232.0
SHD1_k127_2504842_4 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000002517 225.0
SHD1_k127_2504842_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000004405 199.0
SHD1_k127_2507563_0 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 413.0
SHD1_k127_2507563_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 338.0
SHD1_k127_2507563_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 316.0
SHD1_k127_2507563_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001237 282.0
SHD1_k127_2507563_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000008665 219.0
SHD1_k127_2507563_5 cyclic nucleotide binding K01420,K21556,K21562 - - 0.0000000000000000000000000000000000000000000000000000000001384 208.0
SHD1_k127_2507563_6 protein-(glutamine-N5) methyltransferase activity K02493,K16868 - 2.1.1.265,2.1.1.297 0.00000000000000000000000000000000000000000000000000000001494 209.0
SHD1_k127_2507563_7 Ferredoxin - - - 0.0000000000000000000000000000000000000000004344 169.0
SHD1_k127_2507563_8 PFAM YHS domain - - - 0.0000004049 57.0
SHD1_k127_2512358_0 PFAM Glycoside hydrolase, family 2 K01192 - 3.2.1.25 1.525e-280 888.0
SHD1_k127_2512358_1 PFAM Major facilitator superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 589.0
SHD1_k127_2522931_0 TonB-dependent receptor - - - 0.0 1372.0
SHD1_k127_2522931_1 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005646 268.0
SHD1_k127_2522931_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000001763 127.0
SHD1_k127_2522931_3 - - - - 0.0000000000000000002035 90.0
SHD1_k127_2524296_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 411.0
SHD1_k127_2524296_1 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 378.0
SHD1_k127_2524296_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000002774 139.0
SHD1_k127_2550580_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 545.0
SHD1_k127_2550580_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 330.0
SHD1_k127_2550580_2 Transcriptional regulator - - - 0.000000000000000000184 104.0
SHD1_k127_2559231_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 0.0 1148.0
SHD1_k127_2559231_1 Predicted Permease Membrane Region K07085 - - 5.046e-254 795.0
SHD1_k127_256012_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 372.0
SHD1_k127_256012_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001995 271.0
SHD1_k127_256012_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase - - - 0.0000000000001899 76.0
SHD1_k127_2568013_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 601.0
SHD1_k127_2568013_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 507.0
SHD1_k127_2568013_2 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007269 269.0
SHD1_k127_2571341_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 404.0
SHD1_k127_2571341_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000276 225.0
SHD1_k127_2571341_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000004271 165.0
SHD1_k127_2571341_3 Bacterial DNA-binding protein K03530 - - 0.00000000000000000000000000000000000003707 145.0
SHD1_k127_2571341_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000001008 130.0
SHD1_k127_2571341_5 - - - - 0.00000000000000000008128 96.0
SHD1_k127_2583950_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 580.0
SHD1_k127_2583950_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 471.0
SHD1_k127_2604558_0 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 405.0
SHD1_k127_2604558_1 translation initiation factor activity K02004,K10939,K12257,K14393 - - 0.0002951 53.0
SHD1_k127_2611358_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 3.451e-271 844.0
SHD1_k127_2611358_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002568 252.0
SHD1_k127_2617259_0 Glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 9.111e-306 971.0
SHD1_k127_2617259_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000002732 190.0
SHD1_k127_2617259_2 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000000004918 108.0
SHD1_k127_2635378_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
SHD1_k127_2635378_1 Outer membrane efflux protein - - - 0.0000000000000000003791 93.0
SHD1_k127_263591_0 Bacterial regulatory protein, Fis family K07713 - - 2.834e-240 751.0
SHD1_k127_263591_1 Glycosyl hydrolase catalytic core - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 507.0
SHD1_k127_263591_2 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 479.0
SHD1_k127_263591_3 Protein of unknown function (DUF1698) K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 411.0
SHD1_k127_263591_4 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 314.0
SHD1_k127_263591_5 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000005283 202.0
SHD1_k127_263591_6 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000002483 126.0
SHD1_k127_263591_7 - - - - 0.000000000000000000001118 98.0
SHD1_k127_263591_8 aminotransferase class I and II K00375 - - 0.00000000000000008932 83.0
SHD1_k127_263591_9 - - - - 0.000000000003181 67.0
SHD1_k127_2648452_0 peptidase K01415,K07386 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 594.0
SHD1_k127_2648452_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000003589 186.0
SHD1_k127_2670855_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 462.0
SHD1_k127_2670855_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
SHD1_k127_2694029_0 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 482.0
SHD1_k127_2694029_1 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
SHD1_k127_2694029_2 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 304.0
SHD1_k127_2694029_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
SHD1_k127_2694029_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
SHD1_k127_2694029_5 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000005773 187.0
SHD1_k127_2694029_6 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000007612 191.0
SHD1_k127_2698603_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 514.0
SHD1_k127_2698603_1 LytTr DNA-binding domain - - - 0.000000000000000000000000000001623 132.0
SHD1_k127_2698603_2 TonB dependent receptor - - - 0.00000001135 62.0
SHD1_k127_2726969_0 Conserved carboxylase domain K03416 - 2.1.3.1 1.887e-262 814.0
SHD1_k127_2726969_1 CoA carboxylase activity K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 7.83e-248 774.0
SHD1_k127_2726969_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000002549 119.0
SHD1_k127_2726969_3 cyclic nucleotide binding K01420,K21556,K21562 - - 0.00000000003132 74.0
SHD1_k127_2734058_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 329.0
SHD1_k127_2748913_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1107.0
SHD1_k127_2748913_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.093e-201 638.0
SHD1_k127_2748913_2 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 501.0
SHD1_k127_2748913_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 366.0
SHD1_k127_2748913_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 298.0
SHD1_k127_2748913_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 286.0
SHD1_k127_2748913_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001883 196.0
SHD1_k127_2748913_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001147 161.0
SHD1_k127_2756761_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 606.0
SHD1_k127_2756761_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000001108 54.0
SHD1_k127_2758742_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 552.0
SHD1_k127_2758742_1 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 494.0
SHD1_k127_2758742_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 370.0
SHD1_k127_2758742_3 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000267 240.0
SHD1_k127_2758742_4 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000006059 220.0
SHD1_k127_2758742_5 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000002782 209.0
SHD1_k127_2758986_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.364e-234 728.0
SHD1_k127_2758986_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 450.0
SHD1_k127_2758986_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 348.0
SHD1_k127_2758986_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000003991 162.0
SHD1_k127_2758986_4 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000002024 140.0
SHD1_k127_2758986_5 - - - - 0.000000000000000000000004086 105.0
SHD1_k127_2758986_6 - - - - 0.0000000000000000002625 98.0
SHD1_k127_2758986_7 Beta-lactamase K18988 - 3.4.16.4 0.0001502 51.0
SHD1_k127_2762818_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 454.0
SHD1_k127_2762818_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 437.0
SHD1_k127_2762818_10 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000001096 230.0
SHD1_k127_2762818_11 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000004317 172.0
SHD1_k127_2762818_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 435.0
SHD1_k127_2762818_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 424.0
SHD1_k127_2762818_4 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 411.0
SHD1_k127_2762818_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 325.0
SHD1_k127_2762818_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 298.0
SHD1_k127_2762818_7 PFAM Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000607 280.0
SHD1_k127_2762818_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
SHD1_k127_2762818_9 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001527 246.0
SHD1_k127_2778290_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 485.0
SHD1_k127_2778290_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 464.0
SHD1_k127_2778290_2 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
SHD1_k127_2778791_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 440.0
SHD1_k127_2778791_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 371.0
SHD1_k127_2778791_2 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 324.0
SHD1_k127_2778791_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 315.0
SHD1_k127_2778791_5 - - - - 0.0000000000000000000000000000000000003205 148.0
SHD1_k127_2778791_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000004888 126.0
SHD1_k127_2778791_7 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000199 132.0
SHD1_k127_2778791_8 Protein of unknown function (DUF1467) - - - 0.00000001316 55.0
SHD1_k127_2790373_0 beta-1,4-mannooligosaccharide phosphorylase K21065 - 3.2.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 458.0
SHD1_k127_2790373_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 455.0
SHD1_k127_2790373_2 Glycogen debranching enzyme - - - 0.0000005461 53.0
SHD1_k127_2790373_3 Tetratricopeptide repeat - - - 0.0007884 49.0
SHD1_k127_2796664_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 312.0
SHD1_k127_2796664_1 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000002011 196.0
SHD1_k127_2796664_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000001384 160.0
SHD1_k127_2796664_3 PAS PAC sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000004959 174.0
SHD1_k127_2803465_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 311.0
SHD1_k127_2803465_1 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 293.0
SHD1_k127_2803465_2 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000009742 181.0
SHD1_k127_2818070_0 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 390.0
SHD1_k127_2818070_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 333.0
SHD1_k127_2818070_2 antisigma factor binding K04749 - - 0.0000000000000000000000000000000000000000000000000001789 188.0
SHD1_k127_2818070_3 - - - - 0.000000007007 65.0
SHD1_k127_2818070_4 Nucleotidyl transferase - - - 0.00006409 51.0
SHD1_k127_2818525_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.987e-224 711.0
SHD1_k127_2818525_1 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 492.0
SHD1_k127_2818525_2 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 338.0
SHD1_k127_2818525_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000002123 197.0
SHD1_k127_282103_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.608e-292 911.0
SHD1_k127_282103_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 8.383e-201 635.0
SHD1_k127_282103_10 Dioxygenase - - - 0.000000000000000000000000000000001476 137.0
SHD1_k127_282103_11 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000001968 112.0
SHD1_k127_282103_2 synthetase, class II (G H P K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 578.0
SHD1_k127_282103_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 418.0
SHD1_k127_282103_4 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004098 256.0
SHD1_k127_282103_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001521 244.0
SHD1_k127_282103_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000001018 235.0
SHD1_k127_282103_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000004899 204.0
SHD1_k127_282103_8 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000006154 190.0
SHD1_k127_282103_9 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000001033 184.0
SHD1_k127_2824926_0 Tetratricopeptide repeat - - - 0.0 1129.0
SHD1_k127_2824926_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000009677 229.0
SHD1_k127_2826775_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.717e-201 635.0
SHD1_k127_2826775_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 507.0
SHD1_k127_2826775_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 311.0
SHD1_k127_2826775_3 - - - - 0.00000000000000000003474 92.0
SHD1_k127_2826775_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0002096 46.0
SHD1_k127_2830389_0 Protein conserved in bacteria - - - 4.593e-210 654.0
SHD1_k127_2830389_1 ATP-grasp domain K01921 - 6.3.2.4 8.456e-204 637.0
SHD1_k127_2837895_0 TonB-dependent receptor - - - 0.0 1110.0
SHD1_k127_2837895_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 497.0
SHD1_k127_2837895_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 484.0
SHD1_k127_2837895_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 455.0
SHD1_k127_2837895_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 340.0
SHD1_k127_2837895_5 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001074 248.0
SHD1_k127_2837895_6 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001299 236.0
SHD1_k127_2837895_7 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000005645 188.0
SHD1_k127_2837895_8 Zn peptidase - - - 0.0000000000000000000000000000000000000007305 158.0
SHD1_k127_2837895_9 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000008201 88.0
SHD1_k127_2844649_0 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 515.0
SHD1_k127_2844649_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000008357 226.0
SHD1_k127_2844649_2 Rieske [2Fe-2S] domain - - - 0.000000000000000000002944 94.0
SHD1_k127_2844649_3 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.000000188 58.0
SHD1_k127_2844649_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000007225 49.0
SHD1_k127_2844649_5 - - - - 0.00007403 48.0
SHD1_k127_2848572_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 1.598e-263 827.0
SHD1_k127_2848572_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.545e-255 797.0
SHD1_k127_2848572_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000003711 76.0
SHD1_k127_2848572_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000001598 64.0
SHD1_k127_2848572_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.407e-236 742.0
SHD1_k127_2848572_3 Proton-conducting membrane transporter K00343 - 1.6.5.3 2.146e-197 628.0
SHD1_k127_2848572_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 587.0
SHD1_k127_2848572_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 316.0
SHD1_k127_2848572_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000001839 151.0
SHD1_k127_2848572_7 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000001645 132.0
SHD1_k127_2848572_8 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000000000000131 117.0
SHD1_k127_2854766_0 Sortilin, neurotensin receptor 3, - - - 0.0 1556.0
SHD1_k127_2854766_1 lactate/malate dehydrogenase, alpha/beta C-terminal domain K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 430.0
SHD1_k127_2854766_10 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
SHD1_k127_2854766_11 - - - - 0.00000000000000000000000000000000000000000000000000000000001 212.0
SHD1_k127_2854766_12 PFAM Uncharacterised protein family UPF0126 - - - 0.000000000000000000000000000000000000000000000000000000009846 205.0
SHD1_k127_2854766_13 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000000000000000000000821 188.0
SHD1_k127_2854766_14 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000008581 178.0
SHD1_k127_2854766_15 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000003056 134.0
SHD1_k127_2854766_16 phosphorelay signal transduction system - - - 0.000000000000000008642 88.0
SHD1_k127_2854766_18 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000257 69.0
SHD1_k127_2854766_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 411.0
SHD1_k127_2854766_3 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 385.0
SHD1_k127_2854766_4 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
SHD1_k127_2854766_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 345.0
SHD1_k127_2854766_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 322.0
SHD1_k127_2854766_7 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 334.0
SHD1_k127_2854766_8 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 307.0
SHD1_k127_2854766_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 254.0
SHD1_k127_288556_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.316e-258 800.0
SHD1_k127_288556_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009717 238.0
SHD1_k127_2886412_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 8.966e-198 621.0
SHD1_k127_2886412_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 320.0
SHD1_k127_2886412_2 DREV methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
SHD1_k127_2886412_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000663 203.0
SHD1_k127_2886412_4 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000003361 114.0
SHD1_k127_2888074_0 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 355.0
SHD1_k127_2888074_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 318.0
SHD1_k127_2888848_0 Sigma-54 interaction domain - - - 4.178e-218 687.0
SHD1_k127_2888848_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 379.0
SHD1_k127_2888848_2 - - - - 0.0000001335 63.0
SHD1_k127_2888848_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0003676 52.0
SHD1_k127_288940_0 PFAM ABC transporter - - - 5.824e-220 687.0
SHD1_k127_288940_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 351.0
SHD1_k127_288940_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000001759 173.0
SHD1_k127_288940_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000003997 168.0
SHD1_k127_288940_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000003592 78.0
SHD1_k127_2889502_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000005145 160.0
SHD1_k127_2889502_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000001002 132.0
SHD1_k127_2897835_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 449.0
SHD1_k127_2897835_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 308.0
SHD1_k127_2897835_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000003062 232.0
SHD1_k127_2897835_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000002321 190.0
SHD1_k127_2897835_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000008399 180.0
SHD1_k127_2897835_5 xylan catabolic process - - - 0.000000000000000000000000000000000000000007358 174.0
SHD1_k127_2897835_6 cell redox homeostasis - - - 0.0000000002108 62.0
SHD1_k127_2898762_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 338.0
SHD1_k127_2898762_1 WD40-like Beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 322.0
SHD1_k127_2898762_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000002143 223.0
SHD1_k127_2917339_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1136.0
SHD1_k127_2917339_1 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 504.0
SHD1_k127_2921856_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 455.0
SHD1_k127_2921856_1 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 442.0
SHD1_k127_2921856_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 327.0
SHD1_k127_2921856_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000007348 144.0
SHD1_k127_2921856_4 Domain of unknown function (DUF4342) - - - 0.000000000005627 69.0
SHD1_k127_2921856_5 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0002803 51.0
SHD1_k127_2928138_0 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004531 256.0
SHD1_k127_2928138_1 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
SHD1_k127_2928138_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000004314 235.0
SHD1_k127_2928138_3 Flotillin K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000399 218.0
SHD1_k127_2928138_4 Pfam Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000001156 213.0
SHD1_k127_2928138_5 Flotillin K07192 - - 0.000000000000000000000000000003082 121.0
SHD1_k127_2943643_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 567.0
SHD1_k127_2943643_1 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 305.0
SHD1_k127_2943643_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 280.0
SHD1_k127_2943643_3 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
SHD1_k127_2943643_5 WD40-like Beta Propeller K03641 - - 0.00000000001335 64.0
SHD1_k127_2952372_0 Radical SAM K06937 - - 3.866e-247 773.0
SHD1_k127_2952372_2 Phage tail tube, TTP, lambda-like - - - 0.000000005967 70.0
SHD1_k127_2952372_3 pilus assembly protein PilW K02672 - - 0.0005888 50.0
SHD1_k127_2955104_0 Beta-lactamase - - - 0.000000000000000000000002735 118.0
SHD1_k127_2976002_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 351.0
SHD1_k127_2976002_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007385 288.0
SHD1_k127_2976002_2 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000000000005087 226.0
SHD1_k127_2976002_3 Cytochrome P460 - - - 0.000000000000000000008557 92.0
SHD1_k127_2984267_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1240.0
SHD1_k127_2984267_1 TPR repeat - - - 0.00000000000000000000000000000000000000004166 166.0
SHD1_k127_2984267_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000003328 118.0
SHD1_k127_2985661_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1019.0
SHD1_k127_2985661_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 433.0
SHD1_k127_2985661_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 403.0
SHD1_k127_2985661_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000002127 126.0
SHD1_k127_2985661_4 Peptidase S46 - - - 0.0000000000000000000000000002147 116.0
SHD1_k127_2990980_0 Type II/IV secretion system protein K02669 - - 4.272e-206 645.0
SHD1_k127_2990980_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 471.0
SHD1_k127_2990980_2 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 466.0
SHD1_k127_2990980_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000001979 247.0
SHD1_k127_2990980_4 RecX family K03565 - - 0.00000000000000000000000000000000000000000000000689 178.0
SHD1_k127_2990980_5 DinB family - - - 0.000000000000000000000000000000003056 134.0
SHD1_k127_2990980_6 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00003569 49.0
SHD1_k127_3001312_0 outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 519.0
SHD1_k127_3001312_1 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 484.0
SHD1_k127_3001312_2 Formate dehydrogenase N, transmembrane K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 473.0
SHD1_k127_3001312_3 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000448 164.0
SHD1_k127_3001312_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000002575 141.0
SHD1_k127_3016016_0 Peptidase family M13 - - - 1.552e-286 896.0
SHD1_k127_3016016_1 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 317.0
SHD1_k127_3016016_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000000000003738 216.0
SHD1_k127_3016230_0 Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 578.0
SHD1_k127_3016230_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 332.0
SHD1_k127_3016230_2 membrane protein (DUF2306) - - - 0.00000000000000000005261 98.0
SHD1_k127_3016230_3 COGs COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid K02014 - - 0.00000000002394 75.0
SHD1_k127_3021946_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 8.306e-215 674.0
SHD1_k127_3021946_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 580.0
SHD1_k127_3021946_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 566.0
SHD1_k127_3021946_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 492.0
SHD1_k127_3021946_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
SHD1_k127_3021946_5 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000006611 189.0
SHD1_k127_3021946_6 methyltransferase activity - - - 0.00000000000000000000000000001081 124.0
SHD1_k127_3031189_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005275 291.0
SHD1_k127_3031189_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 260.0
SHD1_k127_3031189_2 cellulose binding - - - 0.000000000000000001861 98.0
SHD1_k127_3031189_3 DinB superfamily - - - 0.0000005215 51.0
SHD1_k127_3031247_0 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 330.0
SHD1_k127_3031247_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001815 247.0
SHD1_k127_3031247_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000003151 208.0
SHD1_k127_3031247_3 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000002967 217.0
SHD1_k127_3031247_4 domain protein - - - 0.00000000000000000000006803 114.0
SHD1_k127_3032983_0 alpha beta alpha domain I - - - 1.058e-208 657.0
SHD1_k127_3032983_1 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 523.0
SHD1_k127_3032983_2 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 381.0
SHD1_k127_3037704_0 Nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 479.0
SHD1_k127_3037704_1 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 378.0
SHD1_k127_3037704_2 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000009788 186.0
SHD1_k127_3037704_3 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000003548 152.0
SHD1_k127_3037704_5 tigrfam pas - - - 0.0005322 49.0
SHD1_k127_3043765_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 521.0
SHD1_k127_3043765_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000001431 231.0
SHD1_k127_3043765_2 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000002958 194.0
SHD1_k127_3043765_3 PEGA domain - - - 0.00000000000000000000000000000000000000000000000000001681 196.0
SHD1_k127_3057018_0 Histidine kinase K02482 - 2.7.13.3 2.707e-259 821.0
SHD1_k127_3057018_1 Response regulator, receiver - - - 0.00001739 51.0
SHD1_k127_306884_0 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 469.0
SHD1_k127_306884_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 362.0
SHD1_k127_306884_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000002722 233.0
SHD1_k127_3072779_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.109e-260 810.0
SHD1_k127_3072779_1 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 330.0
SHD1_k127_3072779_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
SHD1_k127_3072779_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000001637 115.0
SHD1_k127_3072933_0 Belongs to the glycosyl hydrolase 57 family - - - 2.091e-316 990.0
SHD1_k127_3072933_1 Malate synthase K01638 - 2.3.3.9 2.035e-248 779.0
SHD1_k127_3072933_2 Isocitrate lyase family K01637 - 4.1.3.1 1.86e-202 639.0
SHD1_k127_3072933_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 510.0
SHD1_k127_3072933_4 excinuclease ABC activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 505.0
SHD1_k127_3072933_5 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 343.0
SHD1_k127_3072933_6 - - - - 0.000000000000000000000000000000000000000004011 160.0
SHD1_k127_3072933_7 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000000000005198 147.0
SHD1_k127_3072933_8 RNA recognition motif - - - 0.00000000000000000000000000001108 123.0
SHD1_k127_3072933_9 - - - - 0.0000000000009558 73.0
SHD1_k127_3078492_0 hydrolase, family 3 K05349 - 3.2.1.21 1.354e-257 816.0
SHD1_k127_3078492_1 D-xylose transmembrane transport K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 521.0
SHD1_k127_3078492_2 ABC transporter K10545,K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000002078 214.0
SHD1_k127_3079372_0 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 482.0
SHD1_k127_3079372_1 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
SHD1_k127_3079372_2 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002708 227.0
SHD1_k127_3079372_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000109 203.0
SHD1_k127_3079372_4 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000005553 134.0
SHD1_k127_3082518_0 Beta-galactosidase - - - 1.107e-268 860.0
SHD1_k127_3082518_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000002632 52.0
SHD1_k127_3082600_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 555.0
SHD1_k127_3082600_1 membrane - - - 0.000000000000000000000000000000000000000006952 158.0
SHD1_k127_3082600_2 membrane - - - 0.000000000000008256 79.0
SHD1_k127_3090385_0 Peptidase S46 - - - 4.668e-222 710.0
SHD1_k127_3090385_1 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001104 280.0
SHD1_k127_3090385_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000008737 156.0
SHD1_k127_3090385_3 Ankyrin repeat - - - 0.0000000000000000000000000000000000005921 150.0
SHD1_k127_3090385_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000007546 141.0
SHD1_k127_3090385_5 Phospholipid methyltransferase - - - 0.000000000000000000000000505 112.0
SHD1_k127_3090385_6 - - - - 0.0000000009595 64.0
SHD1_k127_3090879_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 437.0
SHD1_k127_3090879_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 302.0
SHD1_k127_3090879_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000002059 195.0
SHD1_k127_3090879_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000002255 160.0
SHD1_k127_3092424_0 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 451.0
SHD1_k127_3092424_1 PFAM Amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 439.0
SHD1_k127_3092424_2 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
SHD1_k127_3092424_3 Yip1 domain - - - 0.00000000000000000000000000000000000000000002952 171.0
SHD1_k127_3092424_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000004186 145.0
SHD1_k127_3092424_5 - - - - 0.0000000546 55.0
SHD1_k127_3109952_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0 1032.0
SHD1_k127_3109952_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.037e-281 875.0
SHD1_k127_3109952_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 576.0
SHD1_k127_3109952_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 500.0
SHD1_k127_3109952_4 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.00000000000000000000000000000000000000008668 155.0
SHD1_k127_3109952_5 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000005665 113.0
SHD1_k127_3109952_6 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000002992 106.0
SHD1_k127_31109_0 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 365.0
SHD1_k127_31109_1 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 314.0
SHD1_k127_31109_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000001588 154.0
SHD1_k127_31109_4 Domain of unknown function (DUF4440) - - - 0.000000000000000000007292 102.0
SHD1_k127_3123269_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 3.319e-275 859.0
SHD1_k127_3123269_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 430.0
SHD1_k127_3123269_10 - - - - 0.00000001476 57.0
SHD1_k127_3123269_2 proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 329.0
SHD1_k127_3123269_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000107 217.0
SHD1_k127_3123269_4 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000001472 186.0
SHD1_k127_3123269_5 COG2755 Lysophospholipase L1 and related - - - 0.00000000000000000000000000000000000000000001112 165.0
SHD1_k127_3123269_6 - - - - 0.000000000000000000000000000000000000000007564 164.0
SHD1_k127_3123269_7 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000003352 150.0
SHD1_k127_3123269_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000001576 136.0
SHD1_k127_3123269_9 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000005323 116.0
SHD1_k127_312645_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 475.0
SHD1_k127_312645_1 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001312 283.0
SHD1_k127_312645_2 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
SHD1_k127_312645_3 Predicted membrane protein (DUF2306) - - - 0.00000000000000000000000000000000000000000000000001002 188.0
SHD1_k127_312645_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000002613 154.0
SHD1_k127_312645_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000004197 117.0
SHD1_k127_312645_6 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000005252 109.0
SHD1_k127_312645_7 Antibiotic biosynthesis monooxygenase - - - 0.0000000000006961 72.0
SHD1_k127_312645_8 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000104 62.0
SHD1_k127_312645_9 Transcriptional regulatory protein, C terminal K02483 - - 0.000776 48.0
SHD1_k127_3127497_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 9.664e-321 1001.0
SHD1_k127_3127497_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 340.0
SHD1_k127_3127497_2 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000005622 218.0
SHD1_k127_3127497_3 PFAM Redoxin - - - 0.0000000000000000000000000000000000000000000000000001804 190.0
SHD1_k127_3127497_4 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000002022 179.0
SHD1_k127_3127497_5 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000004042 130.0
SHD1_k127_3127497_6 - - - - 0.000000000000000000000001878 108.0
SHD1_k127_3127497_7 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000001114 96.0
SHD1_k127_3137622_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 3.335e-271 843.0
SHD1_k127_3137622_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 509.0
SHD1_k127_3137622_2 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 440.0
SHD1_k127_3137622_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 348.0
SHD1_k127_3137622_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002827 283.0
SHD1_k127_3137622_5 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0000000000000000000000000000000000000000001742 162.0
SHD1_k127_3137622_6 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000004393 150.0
SHD1_k127_3141411_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.912e-246 772.0
SHD1_k127_3141411_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.245e-233 729.0
SHD1_k127_3156146_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 298.0
SHD1_k127_3156146_1 carbon utilization K02664,K02665,K12280 - - 0.00000000000000000000000000000000000000000000004415 177.0
SHD1_k127_3156146_2 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000008672 169.0
SHD1_k127_3166711_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1272.0
SHD1_k127_3166711_1 Alpha amylase - - - 7.784e-226 711.0
SHD1_k127_3166711_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 470.0
SHD1_k127_3166711_11 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 466.0
SHD1_k127_3166711_12 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 451.0
SHD1_k127_3166711_13 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 443.0
SHD1_k127_3166711_14 Belongs to the heat shock protein 70 family K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 434.0
SHD1_k127_3166711_15 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 422.0
SHD1_k127_3166711_16 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 412.0
SHD1_k127_3166711_17 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 387.0
SHD1_k127_3166711_18 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
SHD1_k127_3166711_19 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 373.0
SHD1_k127_3166711_2 extracellular solute-binding protein, family 5 K02035 - - 1.154e-202 645.0
SHD1_k127_3166711_20 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
SHD1_k127_3166711_21 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 341.0
SHD1_k127_3166711_22 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 302.0
SHD1_k127_3166711_23 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001486 273.0
SHD1_k127_3166711_24 PAS PAC sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002208 287.0
SHD1_k127_3166711_25 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
SHD1_k127_3166711_26 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 263.0
SHD1_k127_3166711_27 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001008 255.0
SHD1_k127_3166711_28 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000009867 252.0
SHD1_k127_3166711_29 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003193 252.0
SHD1_k127_3166711_3 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 593.0
SHD1_k127_3166711_30 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000007707 230.0
SHD1_k127_3166711_31 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000001433 205.0
SHD1_k127_3166711_32 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000241 205.0
SHD1_k127_3166711_33 heme a metabolic process K02259,K03110 - - 0.000000000000000000000000000000000000000000002792 177.0
SHD1_k127_3166711_34 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000009555 170.0
SHD1_k127_3166711_35 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000002402 155.0
SHD1_k127_3166711_36 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000001026 149.0
SHD1_k127_3166711_37 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000001296 154.0
SHD1_k127_3166711_38 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000008944 120.0
SHD1_k127_3166711_39 deacetylase K22278 - 3.5.1.104 0.00000000000000009835 91.0
SHD1_k127_3166711_4 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 574.0
SHD1_k127_3166711_40 Domain of unknown function (DUF4440) - - - 0.00000003199 62.0
SHD1_k127_3166711_41 Cupin 2, conserved barrel domain protein - - - 0.0000001123 62.0
SHD1_k127_3166711_42 Regulatory protein, FmdB family - - - 0.0000005779 55.0
SHD1_k127_3166711_5 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 565.0
SHD1_k127_3166711_6 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 560.0
SHD1_k127_3166711_7 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 544.0
SHD1_k127_3166711_8 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 535.0
SHD1_k127_3166711_9 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 512.0
SHD1_k127_316717_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 344.0
SHD1_k127_316717_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000001746 207.0
SHD1_k127_316717_2 Domain of unknown function (DUF4382) - - - 0.0000000000000000000001595 109.0
SHD1_k127_316717_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000016 99.0
SHD1_k127_3173081_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1391.0
SHD1_k127_3173081_1 ASPIC and UnbV - - - 6.073e-317 977.0
SHD1_k127_3173081_2 ASPIC and UnbV - - - 3.594e-268 836.0
SHD1_k127_3173081_3 Trehalase K01194 - 3.2.1.28 7.542e-211 668.0
SHD1_k127_3173081_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 323.0
SHD1_k127_3173081_5 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000000000000000001685 189.0
SHD1_k127_3174035_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.414e-238 747.0
SHD1_k127_3174035_1 Transposase domain (DUF772) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 339.0
SHD1_k127_3174035_2 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000004501 207.0
SHD1_k127_3174035_3 - - - - 0.000000000000000000000000000000000000001035 152.0
SHD1_k127_3183320_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 1.456e-301 938.0
SHD1_k127_3183320_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 348.0
SHD1_k127_3183320_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000000000000000000000000000000000001864 150.0
SHD1_k127_3192391_0 Serine aminopeptidase, S33 K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 439.0
SHD1_k127_3192391_1 - - - - 0.000000000000000000000000000000000000000000000000000003757 201.0
SHD1_k127_3192391_2 - - - - 0.00000000000000000000000000000000001019 143.0
SHD1_k127_3192391_3 Uncharacterized conserved protein (DUF2164) - - - 0.00000000000000000000000000001732 123.0
SHD1_k127_3192391_4 Putative regulatory protein - - - 0.00000000000000009124 82.0
SHD1_k127_319256_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1046.0
SHD1_k127_319256_1 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 396.0
SHD1_k127_319256_2 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000007717 231.0
SHD1_k127_319256_3 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.0000000801 61.0
SHD1_k127_3203118_0 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 486.0
SHD1_k127_3203118_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
SHD1_k127_3203118_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000001451 213.0
SHD1_k127_3203118_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000007536 191.0
SHD1_k127_3213679_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.994e-197 623.0
SHD1_k127_3213679_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 478.0
SHD1_k127_3213679_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 438.0
SHD1_k127_3213679_3 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 319.0
SHD1_k127_3213679_4 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
SHD1_k127_3222884_0 PFAM peptidase M13 K01415 - 3.4.24.71 1.126e-197 638.0
SHD1_k127_3222884_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 607.0
SHD1_k127_3222884_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 549.0
SHD1_k127_3222884_3 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 534.0
SHD1_k127_3222884_4 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 353.0
SHD1_k127_3222884_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000242 196.0
SHD1_k127_3222884_6 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000009559 156.0
SHD1_k127_3222884_7 Anti-sigma-K factor rskA - - - 0.0000000000002929 79.0
SHD1_k127_3234708_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.256e-214 668.0
SHD1_k127_3234708_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.144e-194 612.0
SHD1_k127_3234708_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 411.0
SHD1_k127_3234708_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001602 96.0
SHD1_k127_3234708_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000002369 81.0
SHD1_k127_3240081_0 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 323.0
SHD1_k127_3240081_1 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 289.0
SHD1_k127_3240081_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
SHD1_k127_3240081_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000008803 176.0
SHD1_k127_3240081_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000004073 164.0
SHD1_k127_3240081_5 Protein of unknown function (DUF1442) - - - 0.000000000000000000000000000002514 127.0
SHD1_k127_3259792_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.71e-235 739.0
SHD1_k127_3259792_1 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 479.0
SHD1_k127_3259792_2 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 305.0
SHD1_k127_3260481_0 ABC transporter K15738 - - 6.429e-242 764.0
SHD1_k127_3260481_1 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 342.0
SHD1_k127_3260481_2 CHASE3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 358.0
SHD1_k127_3260481_3 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005028 252.0
SHD1_k127_3260481_4 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000003005 203.0
SHD1_k127_3260481_5 Helix-turn-helix domain - - - 0.0000000000000000000000000000005715 126.0
SHD1_k127_3260481_6 - - - - 0.0000000000000004847 85.0
SHD1_k127_3264639_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.546e-208 654.0
SHD1_k127_3264639_1 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 456.0
SHD1_k127_3264639_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 398.0
SHD1_k127_3264639_3 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000006149 190.0
SHD1_k127_3264639_4 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000373 152.0
SHD1_k127_3264639_5 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000001806 127.0
SHD1_k127_3264639_6 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000003008 98.0
SHD1_k127_3264639_7 Protein of unknown function (DUF465) - - - 0.00000000000000004201 83.0
SHD1_k127_3264639_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00001278 53.0
SHD1_k127_3270524_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1244.0
SHD1_k127_3270524_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000005194 166.0
SHD1_k127_3279806_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 570.0
SHD1_k127_3279806_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 496.0
SHD1_k127_3282925_0 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 312.0
SHD1_k127_3282925_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 294.0
SHD1_k127_3282925_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000274 96.0
SHD1_k127_3289724_0 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 331.0
SHD1_k127_3289724_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 308.0
SHD1_k127_3289724_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005447 287.0
SHD1_k127_3289724_3 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001436 261.0
SHD1_k127_3289724_4 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000002919 185.0
SHD1_k127_3289724_5 - - - - 0.0000000000000000000009293 102.0
SHD1_k127_3289724_6 Calcineurin-like phosphoesterase - - - 0.0000001449 55.0
SHD1_k127_3294191_0 Carboxypeptidase regulatory-like domain - - - 0.0 1365.0
SHD1_k127_3294191_1 TipAS antibiotic-recognition domain - - - 0.0000000000000000000000000000000000000000000000000000000000000321 222.0
SHD1_k127_3294191_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001019 190.0
SHD1_k127_3294191_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000003981 130.0
SHD1_k127_3294191_4 PAS domain - - - 0.000000000000000002151 86.0
SHD1_k127_332840_0 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001868 272.0
SHD1_k127_332840_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 254.0
SHD1_k127_332840_2 B3/4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000009917 216.0
SHD1_k127_332840_3 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000002707 210.0
SHD1_k127_332840_4 PFAM Alcohol dehydrogenase K12957,K13979 - - 0.0000000000000000000006427 98.0
SHD1_k127_332840_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000131 76.0
SHD1_k127_3340244_0 Elongation factor G, domain IV K02355 - - 0.0 1101.0
SHD1_k127_3340244_1 PFAM natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 602.0
SHD1_k127_3340244_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 604.0
SHD1_k127_3340244_3 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 356.0
SHD1_k127_3340244_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
SHD1_k127_3340244_5 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
SHD1_k127_3340244_6 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000002174 190.0
SHD1_k127_3340244_7 peroxiredoxin activity K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000002782 160.0
SHD1_k127_3340244_8 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.000000000001381 69.0
SHD1_k127_334676_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 6.871e-210 662.0
SHD1_k127_334676_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000001124 53.0
SHD1_k127_334676_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000001466 53.0
SHD1_k127_3358383_0 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 434.0
SHD1_k127_3358383_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 338.0
SHD1_k127_3358383_2 Histidine kinase K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001306 241.0
SHD1_k127_3358383_3 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms - - - 0.00000000000000000000000000000000000000000000000005785 183.0
SHD1_k127_3358383_4 Lipoprotein amino terminal region - - - 0.000000000000000000001474 107.0
SHD1_k127_3360918_0 Predicted Permease Membrane Region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 557.0
SHD1_k127_3360918_1 Aminotransferase class I and II K09758 - 4.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 315.0
SHD1_k127_3360918_2 Na( )-dependent transporter - - - 0.000000000000000000000000004251 121.0
SHD1_k127_3382221_0 Belongs to the OprB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 554.0
SHD1_k127_3382221_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 421.0
SHD1_k127_3382221_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 378.0
SHD1_k127_3382221_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000006249 125.0
SHD1_k127_3409820_0 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 321.0
SHD1_k127_3409820_1 - - - - 0.0000000000000000000000000000000000000000000000000000005688 203.0
SHD1_k127_3409820_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000006473 180.0
SHD1_k127_3409820_3 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.0000000000000000000000000000000006967 134.0
SHD1_k127_3409820_4 - - - - 0.0000000000000000000002609 108.0
SHD1_k127_3409820_5 methyltransferase - - - 0.0000002007 55.0
SHD1_k127_3429239_0 Protein of unknown function (DUF1800) - - - 1.253e-220 701.0
SHD1_k127_3429239_1 Protein of unknown function (DUF1501) - - - 5.415e-197 620.0
SHD1_k127_3430420_0 Aromatic amino acid lyase K01745 - 4.3.1.3 3.482e-219 692.0
SHD1_k127_3430420_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 539.0
SHD1_k127_3430420_2 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 489.0
SHD1_k127_3430420_3 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000000001096 192.0
SHD1_k127_3430420_4 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000000000000001385 184.0
SHD1_k127_3430420_5 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000002149 107.0
SHD1_k127_3439133_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1242.0
SHD1_k127_3439133_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 295.0
SHD1_k127_3451372_0 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 537.0
SHD1_k127_3451372_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 524.0
SHD1_k127_3451372_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 407.0
SHD1_k127_3451372_3 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
SHD1_k127_3451372_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 286.0
SHD1_k127_3451372_5 - - - - 0.00000000000000000000000000000000000000000000000006569 181.0
SHD1_k127_3451372_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000005819 171.0
SHD1_k127_3451372_7 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000002552 115.0
SHD1_k127_3451372_8 - - - - 0.0000000000000000001597 95.0
SHD1_k127_3451372_9 SMART Tetratricopeptide repeat - - - 0.0001439 52.0
SHD1_k127_348144_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.317e-231 734.0
SHD1_k127_348144_1 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 484.0
SHD1_k127_348144_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 418.0
SHD1_k127_348144_3 Chemotaxis protein CheA K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 407.0
SHD1_k127_348144_4 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000004345 211.0
SHD1_k127_348144_5 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000003341 97.0
SHD1_k127_348144_6 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000182 103.0
SHD1_k127_348144_7 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.00000004988 54.0
SHD1_k127_3498071_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 2.556e-217 685.0
SHD1_k127_3498071_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 589.0
SHD1_k127_3498071_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000005174 239.0
SHD1_k127_3498071_3 chaperone-mediated protein folding - - - 0.0000000000000000000000000009563 120.0
SHD1_k127_3498071_4 Thioredoxin-like - - - 0.000000000000000000001059 103.0
SHD1_k127_3498071_5 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.0000008413 57.0
SHD1_k127_350513_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1476.0
SHD1_k127_350513_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 2.337e-205 650.0
SHD1_k127_350513_2 - - - - 0.000000000000000000000000002447 117.0
SHD1_k127_3520232_0 TonB-dependent receptor K13735,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 341.0
SHD1_k127_3520232_1 Sel1-like repeats. K07126,K13582 - - 0.00005705 55.0
SHD1_k127_3553449_0 FAD dependent oxidoreductase K00514 - 1.3.5.6 2.096e-202 641.0
SHD1_k127_3553449_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 578.0
SHD1_k127_3553449_10 membrane - - - 0.00000003239 54.0
SHD1_k127_3553449_2 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 569.0
SHD1_k127_3553449_3 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 529.0
SHD1_k127_3553449_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 475.0
SHD1_k127_3553449_5 TIGRFAM hopanoid-associated sugar epimerase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 446.0
SHD1_k127_3553449_6 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 432.0
SHD1_k127_3553449_7 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 372.0
SHD1_k127_3553449_8 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000842 118.0
SHD1_k127_3553449_9 - - - - 0.0000000000009199 77.0
SHD1_k127_3564679_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 439.0
SHD1_k127_3564679_1 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 330.0
SHD1_k127_3564679_2 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 308.0
SHD1_k127_3564679_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 307.0
SHD1_k127_3564679_4 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 289.0
SHD1_k127_3564679_5 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000002675 166.0
SHD1_k127_3564679_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000001502 132.0
SHD1_k127_3564679_7 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000005208 128.0
SHD1_k127_3564679_8 synthase - - - 0.000000000001102 68.0
SHD1_k127_3564679_9 Aromatic acid exporter family member 1 - - - 0.00000002896 62.0
SHD1_k127_3570437_0 - - - - 0.0000000000000000000000000000003988 130.0
SHD1_k127_3570437_1 protein conserved in bacteria - - - 0.0000000000000000000000509 100.0
SHD1_k127_3570437_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000002577 61.0
SHD1_k127_3570437_3 PFAM transposase IS3 IS911 family protein - - - 0.000009026 49.0
SHD1_k127_3571483_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 413.0
SHD1_k127_3571483_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 362.0
SHD1_k127_3571483_2 - - - - 0.000000000000000000000000000000000000000000000000007614 188.0
SHD1_k127_3571483_3 Intracellular proteinase inhibitor - - - 0.000000000000000000000000001527 117.0
SHD1_k127_3571483_4 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000832 83.0
SHD1_k127_3571483_5 - - - - 0.000000000005951 72.0
SHD1_k127_3571483_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000462 48.0
SHD1_k127_3574026_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1298.0
SHD1_k127_3574026_1 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 2.592e-281 880.0
SHD1_k127_3574026_10 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.000000000000000001765 88.0
SHD1_k127_3574026_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.861e-219 687.0
SHD1_k127_3574026_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 513.0
SHD1_k127_3574026_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 452.0
SHD1_k127_3574026_5 Hydrolase CocE NonD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 373.0
SHD1_k127_3574026_6 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 347.0
SHD1_k127_3574026_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 347.0
SHD1_k127_3574026_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000005636 259.0
SHD1_k127_3574026_9 Transmembrane secretion effector K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000006816 202.0
SHD1_k127_3587131_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 453.0
SHD1_k127_3587131_1 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 310.0
SHD1_k127_3587131_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005771 247.0
SHD1_k127_3587474_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00138,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.0 1076.0
SHD1_k127_3587474_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00138,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 427.0
SHD1_k127_3594969_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 331.0
SHD1_k127_3594969_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
SHD1_k127_3594969_2 - K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000009474 164.0
SHD1_k127_3594969_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000004869 49.0
SHD1_k127_35976_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 315.0
SHD1_k127_35976_1 DDE domain K07498 - - 0.00000000000000000000000000000000002129 137.0
SHD1_k127_35976_2 DDE domain K07498 - - 0.00000000000000000000000002031 110.0
SHD1_k127_35976_3 Transposase and inactivated derivatives - - - 0.000000000000000000002643 96.0
SHD1_k127_35976_5 DDE domain K07498 - - 0.0005948 42.0
SHD1_k127_3601317_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.384e-309 954.0
SHD1_k127_3601317_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 370.0
SHD1_k127_3601317_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 297.0
SHD1_k127_3601317_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 295.0
SHD1_k127_3601317_4 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007492 258.0
SHD1_k127_3601317_5 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001633 205.0
SHD1_k127_3601317_6 - - - - 0.0000000000000000000000000000000000001173 146.0
SHD1_k127_3601317_8 Bacterial regulatory proteins, tetR family - - - 0.000000001873 66.0
SHD1_k127_360218_0 Sortilin, neurotensin receptor 3, - - - 0.0 1172.0
SHD1_k127_360218_1 glutamine synthetase K01915 - 6.3.1.2 4.03e-271 839.0
SHD1_k127_360218_2 GTP-binding protein TypA K06207 - - 1.248e-223 699.0
SHD1_k127_360218_3 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 288.0
SHD1_k127_360218_4 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
SHD1_k127_3602826_0 Glycosyl hydrolases family 2 K15855 - 3.2.1.165 8.746e-244 773.0
SHD1_k127_3602826_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 522.0
SHD1_k127_3602826_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 371.0
SHD1_k127_3602826_3 Transcriptional regulator, DeoR K02081 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 308.0
SHD1_k127_3602826_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 299.0
SHD1_k127_3602826_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 268.0
SHD1_k127_3602826_6 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000003711 170.0
SHD1_k127_3602826_7 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0000000000000000000000000000003197 123.0
SHD1_k127_3604100_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 511.0
SHD1_k127_3604100_1 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 422.0
SHD1_k127_3604100_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000005865 154.0
SHD1_k127_3614873_0 Serine carboxypeptidase - - - 2.608e-200 638.0
SHD1_k127_3614873_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 597.0
SHD1_k127_3616189_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.743e-206 648.0
SHD1_k127_3616189_1 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 407.0
SHD1_k127_3616189_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000007259 142.0
SHD1_k127_3616189_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000003007 126.0
SHD1_k127_3616189_4 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.000004154 53.0
SHD1_k127_3622039_0 Alpha-amylase domain K01187 - 3.2.1.20 1.725e-202 648.0
SHD1_k127_3622039_1 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000002232 185.0
SHD1_k127_3622039_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000001854 183.0
SHD1_k127_3625102_0 Involved in the tonB-independent uptake of proteins - - - 2.439e-309 970.0
SHD1_k127_3625102_1 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 5.67e-210 664.0
SHD1_k127_3625102_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000001785 85.0
SHD1_k127_3650660_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 398.0
SHD1_k127_3650660_1 - - - - 0.0000000000000000000000000000000000000885 148.0
SHD1_k127_3653061_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 592.0
SHD1_k127_3653061_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 422.0
SHD1_k127_3653061_2 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 385.0
SHD1_k127_3653061_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 371.0
SHD1_k127_3653061_4 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 320.0
SHD1_k127_3653061_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000007733 166.0
SHD1_k127_3653061_6 deoxyhypusine monooxygenase activity - - - 0.0000001911 64.0
SHD1_k127_3653061_7 SMART Tetratricopeptide - - - 0.000003121 61.0
SHD1_k127_3667188_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
SHD1_k127_3667188_1 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
SHD1_k127_3667188_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002645 247.0
SHD1_k127_3667188_3 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000002181 105.0
SHD1_k127_3667188_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000012 85.0
SHD1_k127_3667188_5 Putative transmembrane protein (PGPGW) - - - 0.0000002326 55.0
SHD1_k127_3667188_6 - - - - 0.000007225 49.0
SHD1_k127_3671267_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1100.0
SHD1_k127_3671267_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 346.0
SHD1_k127_3671267_2 Transcriptional regulator K07506 - - 0.00000000000000000000000003273 116.0
SHD1_k127_3671267_3 domain, Protein - - - 0.000000001414 67.0
SHD1_k127_3671267_5 Kelch motif - - - 0.000000579 59.0
SHD1_k127_3671267_6 Cytochrome c K00412 - - 0.0001854 49.0
SHD1_k127_3681053_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 475.0
SHD1_k127_3681053_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 417.0
SHD1_k127_3681053_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 261.0
SHD1_k127_3681053_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000299 256.0
SHD1_k127_3681053_4 Zinc dependent phospholipase C - - - 0.00000001333 61.0
SHD1_k127_3699171_0 IgA Peptidase M64 - - - 9.077e-195 618.0
SHD1_k127_3699171_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 520.0
SHD1_k127_3699171_2 Aldose 1-epimerase K01792 - 5.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 307.0
SHD1_k127_3699171_3 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000003928 252.0
SHD1_k127_3699171_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000102 87.0
SHD1_k127_3699171_5 Histidine Phosphotransfer domain K13924 - 2.1.1.80,3.1.1.61 0.000004196 52.0
SHD1_k127_3716092_0 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 520.0
SHD1_k127_3716092_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 275.0
SHD1_k127_3716092_2 ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000009947 189.0
SHD1_k127_3722166_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 393.0
SHD1_k127_3722166_1 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 355.0
SHD1_k127_3722166_2 Kelch motif - - - 0.000000000000000000004533 100.0
SHD1_k127_3724333_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1283.0
SHD1_k127_3724333_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 293.0
SHD1_k127_3725665_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 5.585e-220 689.0
SHD1_k127_3725665_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000003622 242.0
SHD1_k127_3725665_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000002305 132.0
SHD1_k127_3725665_4 Prokaryotic N-terminal methylation motif K02456,K02655 - - 0.0000008074 57.0
SHD1_k127_3742228_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 440.0
SHD1_k127_3742228_1 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001137 251.0
SHD1_k127_3758425_0 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
SHD1_k127_3758425_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003355 262.0
SHD1_k127_3758425_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001836 244.0
SHD1_k127_3758425_3 Phosphoesterase family K21302 - 3.1.3.64 0.0000000000000000000000000000000000000000000000000000000000000000000001345 253.0
SHD1_k127_3758425_4 PAS PAC sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000002498 213.0
SHD1_k127_3758425_5 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000001001 136.0
SHD1_k127_3758425_6 Domain of unknown function (DUF4126) - - - 0.000000000000000000000001506 105.0
SHD1_k127_3758425_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000004523 98.0
SHD1_k127_3764736_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001788 276.0
SHD1_k127_3764736_1 - - - - 0.000000000000000000000000000000000000000000000000000000000004176 218.0
SHD1_k127_3764736_2 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000299 215.0
SHD1_k127_3764736_3 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000001036 186.0
SHD1_k127_3764736_5 antisigma factor binding K04749,K06378 - - 0.000005759 57.0
SHD1_k127_3797995_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 566.0
SHD1_k127_3797995_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 541.0
SHD1_k127_3797995_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 363.0
SHD1_k127_3797995_3 Uncharacterized conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 312.0
SHD1_k127_3797995_4 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000005495 184.0
SHD1_k127_3797995_5 exo-alpha-(2->6)-sialidase activity K01406 - 3.4.24.40 0.000000000000000000000000008431 124.0
SHD1_k127_3797995_6 hyperosmotic response K04065 - - 0.0000000000000000000009918 107.0
SHD1_k127_3799421_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.389e-316 981.0
SHD1_k127_3799421_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 359.0
SHD1_k127_3799421_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000004565 141.0
SHD1_k127_3799421_3 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000007139 90.0
SHD1_k127_380454_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 565.0
SHD1_k127_380454_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000009346 68.0
SHD1_k127_3805522_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 556.0
SHD1_k127_3805522_1 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 489.0
SHD1_k127_3805522_10 - - - - 0.0000000002832 65.0
SHD1_k127_3805522_11 acyl carrier protein - - - 0.000000003247 61.0
SHD1_k127_3805522_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000431 258.0
SHD1_k127_3805522_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000000000002755 239.0
SHD1_k127_3805522_4 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000505 236.0
SHD1_k127_3805522_5 DoxX K15977 - - 0.000000000000000000000000000000000000000225 160.0
SHD1_k127_3805522_6 Sulfate permease family K03321 - - 0.0000000000000000000000000000000003443 136.0
SHD1_k127_3805522_7 Cold shock K03704 - - 0.00000000000000000000000004648 108.0
SHD1_k127_3805522_8 - - - - 0.000000000000000000001445 99.0
SHD1_k127_3805522_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000002137 75.0
SHD1_k127_3817351_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 1.351e-217 681.0
SHD1_k127_3817351_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 584.0
SHD1_k127_3817351_2 histidyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000001806 235.0
SHD1_k127_3825533_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 354.0
SHD1_k127_3825533_1 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 291.0
SHD1_k127_3825533_2 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000006285 218.0
SHD1_k127_3825533_3 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000004794 166.0
SHD1_k127_3825533_4 Protein conserved in bacteria - - - 0.00000000000000000001087 106.0
SHD1_k127_3827864_0 PFAM peptidase M61 - - - 0.0 1007.0
SHD1_k127_3827864_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.262e-299 926.0
SHD1_k127_3827864_10 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000000000000000000007735 117.0
SHD1_k127_3827864_11 Crp Fnr family K21564 - - 0.0000000000000000002798 97.0
SHD1_k127_3827864_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000001178 65.0
SHD1_k127_3827864_13 - - - - 0.00000009815 62.0
SHD1_k127_3827864_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 529.0
SHD1_k127_3827864_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 434.0
SHD1_k127_3827864_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 342.0
SHD1_k127_3827864_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 311.0
SHD1_k127_3827864_7 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005432 264.0
SHD1_k127_3827864_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000006545 207.0
SHD1_k127_3827864_9 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000327 152.0
SHD1_k127_3830524_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000001786 212.0
SHD1_k127_3830524_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000007707 132.0
SHD1_k127_3830524_2 cAMP biosynthetic process - - - 0.0000000000000000000000005376 107.0
SHD1_k127_3830524_3 lipase activity K15349 - - 0.000000000001983 81.0
SHD1_k127_3839549_0 Putative modulator of DNA gyrase K03568 - - 3.468e-255 793.0
SHD1_k127_3839549_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 564.0
SHD1_k127_3839549_2 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002115 273.0
SHD1_k127_3839549_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000008214 209.0
SHD1_k127_3839549_4 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000004157 95.0
SHD1_k127_3857609_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.091e-242 757.0
SHD1_k127_3857609_1 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.000000000000004228 81.0
SHD1_k127_3874776_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 294.0
SHD1_k127_3874776_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000004834 109.0
SHD1_k127_3874776_3 - - - - 0.000000003965 63.0
SHD1_k127_3874776_4 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000001466 53.0
SHD1_k127_3878913_0 diguanylate cyclase K02030,K06950,K16923 - - 0.0 1058.0
SHD1_k127_3878913_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 333.0
SHD1_k127_3883257_0 TonB-dependent Receptor Plug Domain K02014,K16092 - - 3.469e-240 763.0
SHD1_k127_3883257_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 330.0
SHD1_k127_3883257_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002067 282.0
SHD1_k127_3883257_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001078 277.0
SHD1_k127_3883257_4 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000001562 206.0
SHD1_k127_3886189_0 Beta-eliminating lyase K01667 - 4.1.99.1 1.985e-239 747.0
SHD1_k127_3886189_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 478.0
SHD1_k127_3886189_10 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000001051 87.0
SHD1_k127_3886189_2 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 427.0
SHD1_k127_3886189_3 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000001132 192.0
SHD1_k127_3886189_4 Superoxide dismutase K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000313 183.0
SHD1_k127_3886189_6 EVE domain - - - 0.00000000000000000000000000000000000000009196 153.0
SHD1_k127_3886189_7 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000001189 154.0
SHD1_k127_3886189_9 - - - - 0.0000000000000000000006186 96.0
SHD1_k127_388759_0 cellulose binding - - - 0.0 1373.0
SHD1_k127_388759_1 Thioesterase superfamily - - - 0.00000000000000000000000000000003296 127.0
SHD1_k127_388759_2 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00006767 49.0
SHD1_k127_3887751_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 422.0
SHD1_k127_3887751_1 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 426.0
SHD1_k127_3887751_2 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006095 279.0
SHD1_k127_3887751_3 epoxide hydrolase K01253,K21159 - 3.3.2.9 0.000000000000000000000000000005019 120.0
SHD1_k127_3887751_4 Methyltransferase domain - - - 0.000000003694 61.0
SHD1_k127_3900892_0 FAD linked oxidases, C-terminal domain - - - 0.0 1203.0
SHD1_k127_3900892_1 Histidine kinase K07636 - 2.7.13.3 8.261e-206 659.0
SHD1_k127_3900892_2 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 348.0
SHD1_k127_3900892_3 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0001727 48.0
SHD1_k127_3911189_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1309.0
SHD1_k127_3911189_1 surface antigen variable number - - - 4.869e-293 933.0
SHD1_k127_3911189_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 6.526e-284 919.0
SHD1_k127_3911189_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007921 250.0
SHD1_k127_3911189_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000001652 210.0
SHD1_k127_3911189_5 - - - - 0.000000000000000000000000000000000000000000000000002791 184.0
SHD1_k127_3911189_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000001572 145.0
SHD1_k127_3911189_7 MoeZ MoeB K21029 - 2.7.7.80 0.000000000004152 66.0
SHD1_k127_3922925_0 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000006372 173.0
SHD1_k127_3922925_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000006138 160.0
SHD1_k127_3933061_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 6.074e-318 983.0
SHD1_k127_3933061_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 339.0
SHD1_k127_3933061_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 311.0
SHD1_k127_3933061_3 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000006797 239.0
SHD1_k127_3935719_0 Bacterial protein of unknown function (DUF885) - - - 2.619e-210 668.0
SHD1_k127_3935719_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 355.0
SHD1_k127_3935719_2 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 281.0
SHD1_k127_3935719_3 Alpha-L-fucosidase - - - 0.00000000000000000000000000000000000000000000000000000000009073 209.0
SHD1_k127_3935719_4 PFAM Chorismate mutase, type II - - - 0.00000000000000000000000004675 110.0
SHD1_k127_3935719_5 - - - - 0.000000000000000000001763 100.0
SHD1_k127_3935719_6 PFAM PKD domain containing protein - - - 0.0000000000000401 83.0
SHD1_k127_3940596_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 523.0
SHD1_k127_3940596_1 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 523.0
SHD1_k127_3940596_2 - - - - 0.0000000000000000001662 98.0
SHD1_k127_3940596_3 Redoxin - - - 0.0000000000608 67.0
SHD1_k127_3945427_0 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 3.945e-304 943.0
SHD1_k127_3945427_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00138,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 348.0
SHD1_k127_3945427_2 Cupin 2, conserved barrel domain protein K00452 GO:0000334,GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0044237,GO:0044248,GO:0051213,GO:0055114 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 340.0
SHD1_k127_3945427_3 oxidation-reduction process K01617,K15067 - 3.5.99.5,4.1.1.77 0.000000000000000000000000000000000000000000000000000000003736 202.0
SHD1_k127_3945427_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 0.0000000000000000000000004479 107.0
SHD1_k127_3963424_0 amino acid K03294 - - 3.431e-206 656.0
SHD1_k127_3963424_1 Transglycosylase SLT domain K08309 - - 1.286e-201 653.0
SHD1_k127_3963424_2 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 355.0
SHD1_k127_3963424_3 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 368.0
SHD1_k127_3963424_5 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000009023 210.0
SHD1_k127_3963424_6 Putative zinc-finger - - - 0.0000000000000000000000000000000001716 138.0
SHD1_k127_3963424_7 - - - - 0.000000000000001567 81.0
SHD1_k127_3963424_8 - - - - 0.0000000000001783 79.0
SHD1_k127_3976887_0 Domain of unknown function (DUF3471) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 504.0
SHD1_k127_3976887_1 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007372 279.0
SHD1_k127_3976887_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000003567 216.0
SHD1_k127_3987521_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 488.0
SHD1_k127_3987521_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000005183 194.0
SHD1_k127_3999656_0 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 7.857e-270 836.0
SHD1_k127_3999656_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 582.0
SHD1_k127_3999656_2 PFAM FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 439.0
SHD1_k127_3999656_3 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000002282 156.0
SHD1_k127_3999656_4 TonB-dependent siderophore receptor family protein K02014 - - 0.0000000000004445 80.0
SHD1_k127_4022108_0 GGDEF domain - - - 7.222e-234 751.0
SHD1_k127_4022108_1 Phosphoesterase family - - - 5.443e-194 627.0
SHD1_k127_4022108_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 291.0
SHD1_k127_4022108_3 PFAM transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 295.0
SHD1_k127_4022108_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002591 294.0
SHD1_k127_4022108_5 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000008467 172.0
SHD1_k127_4022108_6 COG3547 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000002447 126.0
SHD1_k127_402873_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 513.0
SHD1_k127_402873_1 Belongs to the glycosyl hydrolase 30 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 300.0
SHD1_k127_402873_2 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000002349 192.0
SHD1_k127_402873_3 CHASE3 domain - - - 0.0000000000006261 70.0
SHD1_k127_4031154_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
SHD1_k127_4031154_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 335.0
SHD1_k127_4031154_2 Maltogenic Amylase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 305.0
SHD1_k127_4031154_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000003186 96.0
SHD1_k127_4043560_0 Ribosomal protein S1 K02945 - - 1.476e-315 974.0
SHD1_k127_4043560_1 Belongs to the peptidase S8 family K13275 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 476.0
SHD1_k127_4043560_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000008098 239.0
SHD1_k127_4066512_0 Alpha amylase - - - 9.452e-258 813.0
SHD1_k127_4066512_1 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 578.0
SHD1_k127_4066512_10 - - - - 0.00000000003529 66.0
SHD1_k127_4066512_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 374.0
SHD1_k127_4066512_3 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 339.0
SHD1_k127_4066512_4 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 291.0
SHD1_k127_4066512_5 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000003518 228.0
SHD1_k127_4066512_6 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000006725 167.0
SHD1_k127_4066512_7 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000002291 175.0
SHD1_k127_4066512_8 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000001199 161.0
SHD1_k127_4066512_9 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000003062 126.0
SHD1_k127_4079392_0 class II (D K K01893 - 6.1.1.22 3.745e-249 775.0
SHD1_k127_4079392_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.182e-213 674.0
SHD1_k127_4079392_10 Acetyltransferase (GNAT) domain - - - 0.00000000000005451 74.0
SHD1_k127_4079392_11 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000468 64.0
SHD1_k127_4079392_12 Lipocalin-like domain - - - 0.0000000008135 66.0
SHD1_k127_4079392_13 Putative adhesin - - - 0.0000005975 61.0
SHD1_k127_4079392_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 580.0
SHD1_k127_4079392_3 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 546.0
SHD1_k127_4079392_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 516.0
SHD1_k127_4079392_5 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 489.0
SHD1_k127_4079392_6 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 334.0
SHD1_k127_4079392_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 321.0
SHD1_k127_4079392_8 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
SHD1_k127_4079392_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000006886 156.0
SHD1_k127_4084964_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 527.0
SHD1_k127_4084964_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 319.0
SHD1_k127_4084964_2 Glycosyl transferases group 1 - - - 0.00000000000000000005568 89.0
SHD1_k127_4085766_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 452.0
SHD1_k127_4085766_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000001081 228.0
SHD1_k127_4085766_2 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000000000000000000000003967 222.0
SHD1_k127_4085766_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001841 221.0
SHD1_k127_4085766_4 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000001443 168.0
SHD1_k127_4085766_5 - - - - 0.000000000000000000000000000000000001177 144.0
SHD1_k127_4085766_6 response regulator - - - 0.000000000000000000000000073 111.0
SHD1_k127_4085766_7 transmembrane transport K16052 - - 0.00000000000000001963 93.0
SHD1_k127_4105268_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 471.0
SHD1_k127_4105268_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 426.0
SHD1_k127_4106771_0 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 355.0
SHD1_k127_4106771_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003936 280.0
SHD1_k127_4106771_2 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000007197 224.0
SHD1_k127_4106771_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000001326 176.0
SHD1_k127_4106771_4 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000001236 92.0
SHD1_k127_4117849_0 PAS domain - - - 2.572e-194 618.0
SHD1_k127_4117849_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 386.0
SHD1_k127_4117849_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 349.0
SHD1_k127_4117849_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
SHD1_k127_4117849_4 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000003144 209.0
SHD1_k127_4117849_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000001425 157.0
SHD1_k127_4117849_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000001222 157.0
SHD1_k127_4117849_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000001001 133.0
SHD1_k127_4117849_8 - - - - 0.0000000000000000005013 95.0
SHD1_k127_4127064_0 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 314.0
SHD1_k127_4127064_1 Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 301.0
SHD1_k127_4127064_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000181 216.0
SHD1_k127_414914_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1021.0
SHD1_k127_414914_1 Prolyl oligopeptidase family - - - 4.502e-245 778.0
SHD1_k127_414914_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 415.0
SHD1_k127_414914_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001861 248.0
SHD1_k127_414914_4 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000001234 152.0
SHD1_k127_4167740_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 591.0
SHD1_k127_4167740_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K00082 - 1.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000001557 271.0
SHD1_k127_4167740_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000625 265.0
SHD1_k127_4167740_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007418 262.0
SHD1_k127_4167740_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000548 144.0
SHD1_k127_4167740_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000002402 138.0
SHD1_k127_4181801_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.353e-222 696.0
SHD1_k127_4181801_1 Abhydrolase domain containing 18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 491.0
SHD1_k127_4181801_2 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 377.0
SHD1_k127_4181801_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 360.0
SHD1_k127_4181801_4 Ribose/Galactose Isomerase K01808,K01819,K21911 GO:0003674,GO:0003824,GO:0004751,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.26,5.3.1.34,5.3.1.6 0.0000000000000000000000000000000000000000000000000000003103 197.0
SHD1_k127_4181801_5 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000007302 145.0
SHD1_k127_4186855_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0 1023.0
SHD1_k127_4186855_1 Phytochrome central region domain protein - - - 9.412e-224 716.0
SHD1_k127_4186855_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 473.0
SHD1_k127_4186855_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000004719 167.0
SHD1_k127_4186855_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000995 168.0
SHD1_k127_4186855_5 heme oxygenase - - - 0.000000000000000000000000000005462 127.0
SHD1_k127_4186855_6 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000008848 59.0
SHD1_k127_4196720_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 553.0
SHD1_k127_4196720_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 378.0
SHD1_k127_4196720_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 328.0
SHD1_k127_4196720_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
SHD1_k127_4197326_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 344.0
SHD1_k127_4197326_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000006609 174.0
SHD1_k127_4197326_2 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000001438 155.0
SHD1_k127_4197326_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000001552 125.0
SHD1_k127_4197326_4 PFAM S-layer domain protein - - - 0.000000000001635 73.0
SHD1_k127_4203480_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 444.0
SHD1_k127_4203480_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 393.0
SHD1_k127_4203480_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000631 219.0
SHD1_k127_4203480_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000002192 123.0
SHD1_k127_4203480_4 - - - - 0.00000000000000000000000000106 126.0
SHD1_k127_4211420_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 3.159e-271 844.0
SHD1_k127_4211420_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 376.0
SHD1_k127_4211420_2 - - - - 0.0000000000000000002775 100.0
SHD1_k127_4219430_0 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 368.0
SHD1_k127_4219430_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 355.0
SHD1_k127_4219430_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000005267 216.0
SHD1_k127_4233944_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 487.0
SHD1_k127_4233944_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 441.0
SHD1_k127_4233944_2 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
SHD1_k127_4233944_3 Serine hydrolase K07002,K19073 - 1.3.1.75 0.0000000000000000000000000001887 117.0
SHD1_k127_4234960_0 DNA polymerase X family K02347 - - 1.967e-271 861.0
SHD1_k127_4234960_1 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 498.0
SHD1_k127_4234960_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 434.0
SHD1_k127_4234960_3 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.00000000000000000000000000000006005 126.0
SHD1_k127_4235488_0 PFAM Response regulator receiver domain K07713 - - 9.819e-251 780.0
SHD1_k127_4235488_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000014 294.0
SHD1_k127_4235488_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000002587 171.0
SHD1_k127_4242976_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1015.0
SHD1_k127_4242976_1 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 3.419e-222 708.0
SHD1_k127_4242976_10 Bacterial PH domain K08981 - - 0.0000000001882 69.0
SHD1_k127_4242976_2 glutathione-regulated potassium exporter activity K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 451.0
SHD1_k127_4242976_3 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 425.0
SHD1_k127_4242976_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 392.0
SHD1_k127_4242976_5 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 385.0
SHD1_k127_4242976_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 376.0
SHD1_k127_4242976_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000002111 246.0
SHD1_k127_4242976_8 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000003925 213.0
SHD1_k127_4242976_9 protein secretion K03116 - - 0.0000000000000000006596 87.0
SHD1_k127_4272376_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 339.0
SHD1_k127_4272376_1 PFAM peptidase K16922 - - 0.000000000000000000000000000000000000000000000001927 196.0
SHD1_k127_4272376_2 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000006497 168.0
SHD1_k127_4282604_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 480.0
SHD1_k127_4282604_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 353.0
SHD1_k127_4282604_2 synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 300.0
SHD1_k127_4282604_3 Periplasmic or secreted lipoprotein - - - 0.000000008293 61.0
SHD1_k127_4290104_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000001024 206.0
SHD1_k127_4290104_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000004092 151.0
SHD1_k127_4290104_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000002257 135.0
SHD1_k127_4323175_0 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 289.0
SHD1_k127_4323175_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000004142 195.0
SHD1_k127_4323175_2 Sporulation related domain - - - 0.0000000001144 71.0
SHD1_k127_4323175_3 L,D-transpeptidase catalytic domain - - - 0.00001613 51.0
SHD1_k127_4333179_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 8.086e-316 977.0
SHD1_k127_4333179_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 439.0
SHD1_k127_4333179_2 - - - - 0.00000000000000002269 91.0
SHD1_k127_4335162_0 Putative glucoamylase K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 384.0
SHD1_k127_4335162_1 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 292.0
SHD1_k127_4335162_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007717 248.0
SHD1_k127_4335162_3 Histidine kinase - - - 0.0000000000000000000000000000000000000002195 157.0
SHD1_k127_4343483_0 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 400.0
SHD1_k127_4343483_1 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 299.0
SHD1_k127_4343483_2 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001754 236.0
SHD1_k127_4343483_3 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000000000000000002061 188.0
SHD1_k127_4343483_4 - - - - 0.00000000000000000000000002955 112.0
SHD1_k127_434442_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 4.401e-285 890.0
SHD1_k127_434442_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000002636 243.0
SHD1_k127_434442_2 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000004536 172.0
SHD1_k127_4348947_0 Patatin-like phospholipase K07001 - - 3.997e-209 673.0
SHD1_k127_4348947_1 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000003057 172.0
SHD1_k127_4354079_0 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 5.807e-229 716.0
SHD1_k127_4354079_1 4Fe-4S dicluster domain K00184,K08358 - - 0.00000000000000000000000000000000000000000000000008315 186.0
SHD1_k127_4354079_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000005886 176.0
SHD1_k127_4354079_3 PFAM 4Fe-4S ferredoxin K08358 - - 0.0000000000000000000000000000000000000133 154.0
SHD1_k127_4354079_4 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000001194 115.0
SHD1_k127_4354079_5 Oxidoreductase FAD-binding domain - - - 0.000000000003836 68.0
SHD1_k127_4362158_0 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 473.0
SHD1_k127_4362158_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000005561 78.0
SHD1_k127_437047_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 313.0
SHD1_k127_437047_1 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
SHD1_k127_437047_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000805 276.0
SHD1_k127_437047_3 DDE domain K07498 - - 0.000000000000000000000000000000000000000000000000000000000000003065 221.0
SHD1_k127_437047_4 glyoxalase III activity - - - 0.00000000000002997 81.0
SHD1_k127_4386804_0 Prolyl oligopeptidase - - - 7.826e-255 798.0
SHD1_k127_4386804_1 sh3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 424.0
SHD1_k127_4386804_2 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000004235 208.0
SHD1_k127_4386804_3 Response regulator, receiver - - - 0.000000000000000000000002671 107.0
SHD1_k127_4386804_4 cheY-homologous receiver domain - - - 0.00000372 50.0
SHD1_k127_4388913_0 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 485.0
SHD1_k127_4388913_1 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 467.0
SHD1_k127_4388913_11 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000000002552 151.0
SHD1_k127_4388913_12 Protein conserved in bacteria - - - 0.00000000000000000000000000000001067 138.0
SHD1_k127_4388913_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 325.0
SHD1_k127_4388913_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 287.0
SHD1_k127_4388913_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366 269.0
SHD1_k127_4388913_5 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001512 267.0
SHD1_k127_4388913_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000007817 220.0
SHD1_k127_4388913_7 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000002551 201.0
SHD1_k127_4388913_8 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000008401 177.0
SHD1_k127_4390315_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1209.0
SHD1_k127_4390315_1 Participates in both transcription termination and antitermination K02600 - - 4.581e-227 713.0
SHD1_k127_4390315_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006925 229.0
SHD1_k127_4390315_3 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000002995 173.0
SHD1_k127_4390315_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000388 153.0
SHD1_k127_4390315_5 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000001147 138.0
SHD1_k127_4390315_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000001116 134.0
SHD1_k127_4395049_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 8.019e-304 960.0
SHD1_k127_4395049_1 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 348.0
SHD1_k127_4395049_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
SHD1_k127_4395049_3 Major Facilitator Superfamily - - - 0.0000000000009199 77.0
SHD1_k127_4414608_0 TonB-dependent Receptor Plug - - - 2.011e-259 825.0
SHD1_k127_4414608_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001029 223.0
SHD1_k127_4415676_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 294.0
SHD1_k127_4415676_1 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000001839 174.0
SHD1_k127_4415676_2 Phage integrase family - - - 0.0000000000000000000000000008705 128.0
SHD1_k127_4419123_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 307.0
SHD1_k127_4419123_1 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 283.0
SHD1_k127_4419123_2 PilZ domain - - - 0.00000000000000000004519 93.0
SHD1_k127_4439251_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.594e-219 684.0
SHD1_k127_4439251_1 Cellulase (glycosyl hydrolase family 5) - - - 8.499e-202 634.0
SHD1_k127_4439251_2 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 568.0
SHD1_k127_4439251_3 Male sterility protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 443.0
SHD1_k127_4439251_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 393.0
SHD1_k127_4439251_6 DinB superfamily - - - 0.00000000000000000000000000000000000001992 150.0
SHD1_k127_4439251_7 DinB superfamily - - - 0.0000000000000000000000000000000000001178 158.0
SHD1_k127_4439251_8 - - - - 0.0000000000000000000000000000000000005091 147.0
SHD1_k127_4439251_9 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000003237 134.0
SHD1_k127_4444363_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 5.991e-235 736.0
SHD1_k127_4444363_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 505.0
SHD1_k127_4444363_2 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 400.0
SHD1_k127_4444363_3 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 376.0
SHD1_k127_4444363_4 TIGRFAM TonB K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 340.0
SHD1_k127_4444363_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 330.0
SHD1_k127_4444363_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003701 241.0
SHD1_k127_4444363_7 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000000001335 212.0
SHD1_k127_4444363_8 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000000000000000000246 204.0
SHD1_k127_4444363_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
SHD1_k127_444472_0 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 426.0
SHD1_k127_444472_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 314.0
SHD1_k127_444472_2 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003818 258.0
SHD1_k127_4452181_0 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 348.0
SHD1_k127_4452181_1 - - - - 0.0000000000001071 73.0
SHD1_k127_4454780_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
SHD1_k127_4454780_1 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000004891 118.0
SHD1_k127_4454780_2 Thioesterase superfamily - - - 0.00000004247 56.0
SHD1_k127_4454780_3 - - - - 0.000003249 55.0
SHD1_k127_4454780_4 photosystem II stabilization K02237 - - 0.000005686 53.0
SHD1_k127_4471356_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 2.503e-220 697.0
SHD1_k127_4471356_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 374.0
SHD1_k127_4471356_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000487 147.0
SHD1_k127_4471356_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000001389 106.0
SHD1_k127_4471356_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000000123 94.0
SHD1_k127_4485107_0 cellulose binding - - - 0.0 1315.0
SHD1_k127_4485107_1 citrate CoA-transferase activity K01643 - 2.8.3.10 1.008e-264 824.0
SHD1_k127_4485107_2 Zinc-binding dehydrogenase K12957,K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 520.0
SHD1_k127_4485107_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 477.0
SHD1_k127_4485107_4 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000002888 142.0
SHD1_k127_4485107_6 Domain of unknown function (DUF5117) - - - 0.00000008617 57.0
SHD1_k127_4487167_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 8.625e-219 686.0
SHD1_k127_450588_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 2.828e-309 960.0
SHD1_k127_450588_1 Fibronectin type III-like domain K05349 - 3.2.1.21 2.129e-269 850.0
SHD1_k127_4512117_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1144.0
SHD1_k127_4512117_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 591.0
SHD1_k127_4512117_2 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
SHD1_k127_4512117_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000213 185.0
SHD1_k127_4512117_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000004188 89.0
SHD1_k127_4540464_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 7.579e-202 637.0
SHD1_k127_4540464_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 486.0
SHD1_k127_4540464_2 photoreceptor activity K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 313.0
SHD1_k127_4540464_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000001862 175.0
SHD1_k127_4540464_4 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000000000000000000000003223 147.0
SHD1_k127_4540464_5 cheY-homologous receiver domain - - - 0.000000000000000009392 83.0
SHD1_k127_454203_0 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
SHD1_k127_454203_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K19270 - 3.1.3.23 0.000000000000000000000000000000000000000000000000000000000000007795 222.0
SHD1_k127_454203_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000116 206.0
SHD1_k127_454203_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000000000000000000000000009235 199.0
SHD1_k127_454203_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000003027 103.0
SHD1_k127_4545723_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 600.0
SHD1_k127_4545723_1 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000003394 156.0
SHD1_k127_4545723_2 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001878 138.0
SHD1_k127_4545723_3 Glutaredoxin - - - 0.000000000000003281 76.0
SHD1_k127_4563243_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 549.0
SHD1_k127_4563243_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 366.0
SHD1_k127_4563243_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000005744 106.0
SHD1_k127_4565471_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 434.0
SHD1_k127_4565471_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000002051 117.0
SHD1_k127_4573547_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 553.0
SHD1_k127_4573547_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 509.0
SHD1_k127_4573547_2 ATP-independent chaperone mediated protein folding K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 355.0
SHD1_k127_4573547_3 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 270.0
SHD1_k127_4573547_4 ATP-independent chaperone mediated protein folding K02005 - - 0.000000000000000000000000000000000009286 140.0
SHD1_k127_4573547_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000009335 91.0
SHD1_k127_4584391_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 582.0
SHD1_k127_4584391_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
SHD1_k127_4611429_0 Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 284.0
SHD1_k127_4611429_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003639 231.0
SHD1_k127_4611429_2 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000001744 201.0
SHD1_k127_4611429_3 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000004056 196.0
SHD1_k127_4611429_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002097 147.0
SHD1_k127_4611429_5 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000001633 98.0
SHD1_k127_4613990_0 Glycogen debranching enzyme - - - 0.0 1523.0
SHD1_k127_4613990_1 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
SHD1_k127_4621565_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003967 280.0
SHD1_k127_4621565_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000004607 246.0
SHD1_k127_4621565_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
SHD1_k127_4639270_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 462.0
SHD1_k127_4639270_1 Sel1-like repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 448.0
SHD1_k127_4639270_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000002185 229.0
SHD1_k127_4647588_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 500.0
SHD1_k127_4647588_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 490.0
SHD1_k127_4647588_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000002585 142.0
SHD1_k127_4647588_4 - - - - 0.0000000003501 66.0
SHD1_k127_4650471_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000008034 209.0
SHD1_k127_4650471_1 - - - - 0.0000000000000000000000001232 113.0
SHD1_k127_4656534_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 1.127e-220 693.0
SHD1_k127_4656534_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 550.0
SHD1_k127_4656534_10 - - - - 0.000001373 50.0
SHD1_k127_4656534_2 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 544.0
SHD1_k127_4656534_3 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004164 265.0
SHD1_k127_4656534_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001254 226.0
SHD1_k127_4656534_5 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000008489 218.0
SHD1_k127_4656534_6 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
SHD1_k127_4656534_7 - - - - 0.00000000000000000000000000000000000000000000000002029 183.0
SHD1_k127_4656534_8 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000000002217 128.0
SHD1_k127_4656534_9 - - - - 0.00000000000000000000000000001964 126.0
SHD1_k127_4658808_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.716e-237 743.0
SHD1_k127_4658808_1 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001595 248.0
SHD1_k127_4658808_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000002354 237.0
SHD1_k127_4658808_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000002363 147.0
SHD1_k127_4665069_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 534.0
SHD1_k127_4665069_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 372.0
SHD1_k127_4665069_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 287.0
SHD1_k127_4665069_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000008683 232.0
SHD1_k127_4665069_4 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.0000000000000000000000000000000006622 130.0
SHD1_k127_4665069_5 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000000000000000000000001616 118.0
SHD1_k127_4665069_6 - - - - 0.00000000004052 71.0
SHD1_k127_4668913_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 557.0
SHD1_k127_4668913_1 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 296.0
SHD1_k127_4668913_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 292.0
SHD1_k127_4668913_3 - - - - 0.00000000000000000000000000000000000000000005318 160.0
SHD1_k127_4668913_4 - - - - 0.00000000000000000000000000000000000000003619 168.0
SHD1_k127_4671977_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 494.0
SHD1_k127_4671977_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001495 241.0
SHD1_k127_4671977_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000002672 158.0
SHD1_k127_4671977_3 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000002706 136.0
SHD1_k127_4671977_4 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000955 96.0
SHD1_k127_4678917_0 heat shock protein binding - - - 1.045e-302 944.0
SHD1_k127_4678917_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 336.0
SHD1_k127_4678917_3 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 333.0
SHD1_k127_4678917_4 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001994 278.0
SHD1_k127_4678917_6 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000001249 164.0
SHD1_k127_468045_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000006062 203.0
SHD1_k127_4693829_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 559.0
SHD1_k127_4693829_4 Gas vesicle protein K - - - 0.0000000000000006654 79.0
SHD1_k127_4703635_0 May be involved in recombinational repair of damaged DNA K03631 - - 3.603e-240 754.0
SHD1_k127_4703635_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 513.0
SHD1_k127_4703635_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 499.0
SHD1_k127_4703635_3 Peptidase family M13 - - - 0.0000000000000000000000000845 106.0
SHD1_k127_4709587_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1182.0
SHD1_k127_4709587_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 8.152e-253 789.0
SHD1_k127_4709587_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.767e-199 626.0
SHD1_k127_4709587_3 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000007583 229.0
SHD1_k127_4709587_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000002912 156.0
SHD1_k127_4712086_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1053.0
SHD1_k127_4712086_1 Bacterial protein of unknown function (DUF885) - - - 3.506e-215 682.0
SHD1_k127_4712086_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 472.0
SHD1_k127_4713730_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1150.0
SHD1_k127_4713730_1 Glycosyl hydrolases family 15 - - - 1.042e-203 651.0
SHD1_k127_4713730_2 - - - - 0.000000000000000000000000000000000000000000000000007357 185.0
SHD1_k127_4713730_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000000005047 158.0
SHD1_k127_4713730_4 Acyltransferase family - - - 0.00000000000000000000000000000005455 130.0
SHD1_k127_4718981_0 cAMP biosynthetic process K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 484.0
SHD1_k127_4718981_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 441.0
SHD1_k127_4718981_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 360.0
SHD1_k127_4718981_3 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 332.0
SHD1_k127_4718981_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000219 288.0
SHD1_k127_4722592_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.78e-312 960.0
SHD1_k127_4722592_1 Amidohydrolase family - - - 2.102e-197 625.0
SHD1_k127_4722592_10 Domain of unknown function (DUF4347) K20276 - - 0.000000000000000000000000001258 130.0
SHD1_k127_4722592_11 nuclear chromosome segregation K02666,K03497,K19622 - - 0.000000000000000000008134 102.0
SHD1_k127_4722592_12 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000006171 87.0
SHD1_k127_4722592_13 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.0000000000000008955 92.0
SHD1_k127_4722592_14 restriction endonuclease - - - 0.0000000000003505 70.0
SHD1_k127_4722592_15 Two component signalling adaptor domain K03408 - - 0.0000002296 59.0
SHD1_k127_4722592_16 Response regulator receiver domain K07658 - - 0.00000375 57.0
SHD1_k127_4722592_17 TPR repeat - - - 0.00007118 54.0
SHD1_k127_4722592_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 391.0
SHD1_k127_4722592_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001482 238.0
SHD1_k127_4722592_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000003477 222.0
SHD1_k127_4722592_5 DNA-binding transcription factor activity - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000007461 203.0
SHD1_k127_4722592_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000008635 184.0
SHD1_k127_4722592_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000004313 166.0
SHD1_k127_4722592_8 - - - - 0.00000000000000000000000000000000000000000352 164.0
SHD1_k127_4722592_9 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K09568 - 5.2.1.8 0.00000000000000000000000000000000003495 149.0
SHD1_k127_4728747_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000004884 180.0
SHD1_k127_4728747_1 - - - - 0.00000000000000000000000000000000000000007027 158.0
SHD1_k127_4728747_2 - - - - 0.0000000000000000000000000003573 121.0
SHD1_k127_4737663_0 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 575.0
SHD1_k127_4737663_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 409.0
SHD1_k127_4737663_2 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001423 271.0
SHD1_k127_4737663_3 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000008708 204.0
SHD1_k127_4737663_4 - - - - 0.000000000000000000000000000000000000003963 156.0
SHD1_k127_4739645_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000003553 172.0
SHD1_k127_4739645_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000007237 141.0
SHD1_k127_4739645_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000004209 123.0
SHD1_k127_4739645_3 - - - - 0.00000000000000000000000000009331 127.0
SHD1_k127_4741351_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1321.0
SHD1_k127_4741351_1 catechol 1,2-dioxygenase - - - 0.00000000000000000006161 97.0
SHD1_k127_4741351_2 Domain of unknown function (DUF4440) - - - 0.00000000000000005967 87.0
SHD1_k127_4741351_3 anaphase-promoting complex binding - - - 0.0000131 56.0
SHD1_k127_4745702_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.378e-239 746.0
SHD1_k127_4745702_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000008542 183.0
SHD1_k127_4745702_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000006889 81.0
SHD1_k127_4757316_0 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 427.0
SHD1_k127_4757316_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 318.0
SHD1_k127_4757316_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 302.0
SHD1_k127_4757316_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 289.0
SHD1_k127_4772841_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1510.0
SHD1_k127_4772841_1 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 351.0
SHD1_k127_4772841_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 344.0
SHD1_k127_4772841_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 322.0
SHD1_k127_4772841_4 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008805 269.0
SHD1_k127_4772841_5 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000001005 113.0
SHD1_k127_4772841_6 - - - - 0.000000000000000000000001573 111.0
SHD1_k127_4772841_7 Protein of unknown function DUF72 - - - 0.0000000000000004687 80.0
SHD1_k127_477428_0 Ammonium Transporter K03320 - - 9.452e-214 671.0
SHD1_k127_477428_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 453.0
SHD1_k127_477428_2 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001241 186.0
SHD1_k127_4776882_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 299.0
SHD1_k127_4776882_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001612 241.0
SHD1_k127_4776882_2 Glutathione peroxidase K02199 - - 0.0000000000000000000000000000000000000000000000000000000001554 209.0
SHD1_k127_4776882_3 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000005325 145.0
SHD1_k127_4776882_4 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000001654 119.0
SHD1_k127_4776882_5 Horizontally Transferred TransMembrane Domain - - - 0.0000000000001341 75.0
SHD1_k127_4777633_0 Glycosyl transferase, family 2 - - - 0.0 1180.0
SHD1_k127_4777633_1 RibD C-terminal domain - - - 0.00000000000000000000000000008907 124.0
SHD1_k127_4777633_2 DNA-binding transcription factor activity - - - 0.00000000000000008 89.0
SHD1_k127_4777633_3 - - - - 0.00000000000002106 78.0
SHD1_k127_47869_0 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 392.0
SHD1_k127_47869_1 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 385.0
SHD1_k127_47869_2 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
SHD1_k127_47869_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 360.0
SHD1_k127_47869_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000003603 201.0
SHD1_k127_4798477_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 555.0
SHD1_k127_4798477_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 351.0
SHD1_k127_4798477_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001546 269.0
SHD1_k127_4798477_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000002601 166.0
SHD1_k127_4798477_4 Zincin-like metallopeptidase - - - 0.0000000000000000000002158 100.0
SHD1_k127_4808276_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 607.0
SHD1_k127_4808276_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 412.0
SHD1_k127_4808276_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 329.0
SHD1_k127_4808276_3 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 319.0
SHD1_k127_4808276_4 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000004837 217.0
SHD1_k127_4826932_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 408.0
SHD1_k127_4826932_1 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 319.0
SHD1_k127_4826932_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 293.0
SHD1_k127_4862266_0 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 6.476e-222 715.0
SHD1_k127_4862266_1 amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 346.0
SHD1_k127_4862266_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000001023 155.0
SHD1_k127_4862266_3 Glutaredoxin - - - 0.0000000000000000000000000000000000000003549 151.0
SHD1_k127_4862266_4 regulation of circadian rhythm - - - 0.0000000000000000001109 96.0
SHD1_k127_4863188_0 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 383.0
SHD1_k127_4863188_1 domain protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 313.0
SHD1_k127_4863188_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007945 274.0
SHD1_k127_4863188_3 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000008055 195.0
SHD1_k127_4863188_4 Lipid A 3-O-deacylase (PagL) - - - 0.00002146 55.0
SHD1_k127_4874438_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 409.0
SHD1_k127_4874438_1 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 411.0
SHD1_k127_4874438_2 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 386.0
SHD1_k127_4874438_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 316.0
SHD1_k127_4874438_4 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001675 262.0
SHD1_k127_4874438_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001013 244.0
SHD1_k127_4874438_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000007008 201.0
SHD1_k127_4874438_7 Likely ribonuclease with RNase H fold. K07447 - - 0.0000000000000000000000000000000000000000000000000003149 189.0
SHD1_k127_4891930_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 440.0
SHD1_k127_4891930_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 439.0
SHD1_k127_4891930_2 SnoaL-like domain - - - 0.000000000000001863 85.0
SHD1_k127_4891930_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000005037 67.0
SHD1_k127_4912182_0 Peptidase dimerisation domain K01270 - - 1.514e-213 672.0
SHD1_k127_4912182_1 PFAM Radical SAM - - - 5.142e-201 632.0
SHD1_k127_4912182_2 PFAM Radical SAM - - - 0.0000000000000000000000002819 105.0
SHD1_k127_4921476_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 525.0
SHD1_k127_4921476_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 425.0
SHD1_k127_4921476_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000817 47.0
SHD1_k127_4921476_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004346 275.0
SHD1_k127_4921476_3 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000009509 189.0
SHD1_k127_4921476_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000001093 190.0
SHD1_k127_4921476_5 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000303 189.0
SHD1_k127_4921476_6 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000005459 179.0
SHD1_k127_4921476_7 - - - - 0.00000000000000000000000000000000000000007784 151.0
SHD1_k127_4921476_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000005434 94.0
SHD1_k127_4921476_9 Belongs to the BI1 family K06890 - - 0.0000000000003726 80.0
SHD1_k127_4923144_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K05587 - 1.6.5.3 2.981e-224 707.0
SHD1_k127_4923144_1 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 3.397e-196 623.0
SHD1_k127_4923144_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 374.0
SHD1_k127_4923144_3 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 303.0
SHD1_k127_4923144_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002188 233.0
SHD1_k127_4923144_5 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000005805 233.0
SHD1_k127_4923144_6 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001682 223.0
SHD1_k127_4923144_7 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000008671 222.0
SHD1_k127_4923144_8 TIGRFAM hydrogenase maturation protease - - - 0.000000000000000000000001736 108.0
SHD1_k127_4939986_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 4.529e-218 692.0
SHD1_k127_4939986_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 405.0
SHD1_k127_4941037_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 546.0
SHD1_k127_4941037_1 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005812 244.0
SHD1_k127_4941037_2 - K07283 - - 0.0000000000000000000000000000000000000000005052 169.0
SHD1_k127_4948274_0 Tetratricopeptide repeat - - - 2.466e-278 872.0
SHD1_k127_4948274_1 Psort location CytoplasmicMembrane, score - - - 3.111e-257 805.0
SHD1_k127_4948274_10 - - - - 0.0000000000000000000000000000000000000000001392 165.0
SHD1_k127_4948274_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000002382 158.0
SHD1_k127_4948274_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 529.0
SHD1_k127_4948274_3 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 517.0
SHD1_k127_4948274_4 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 445.0
SHD1_k127_4948274_5 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 432.0
SHD1_k127_4948274_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 335.0
SHD1_k127_4948274_7 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 330.0
SHD1_k127_4948274_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
SHD1_k127_4948274_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001203 224.0
SHD1_k127_4949636_0 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 293.0
SHD1_k127_4949636_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
SHD1_k127_4949636_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
SHD1_k127_4951927_0 PFAM TonB-dependent Receptor - - - 1.052e-219 716.0
SHD1_k127_4951927_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000008712 103.0
SHD1_k127_4951927_2 Carboxypeptidase regulatory-like domain - - - 0.0001254 50.0
SHD1_k127_4953209_0 Protein of unknown function (DUF1343) - - - 1.228e-294 921.0
SHD1_k127_4953209_1 HD domain - - - 1.136e-199 626.0
SHD1_k127_4953209_2 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
SHD1_k127_4953209_3 multi-organism process K03195 - - 0.000000000000000000000000000000000000000000000000000000000005911 216.0
SHD1_k127_4953209_4 cellular response to heat K09807 - - 0.000000000000000000000000000000000000000001594 166.0
SHD1_k127_4953209_5 Histidine kinase K02482,K03557 - 2.7.13.3 0.0000000000000000000000000000001236 133.0
SHD1_k127_4953209_6 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000006759 104.0
SHD1_k127_4961904_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 7.04e-232 721.0
SHD1_k127_4961904_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 606.0
SHD1_k127_4961904_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 470.0
SHD1_k127_4961904_3 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 376.0
SHD1_k127_4961904_4 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 327.0
SHD1_k127_4961904_5 Regulatory protein - - - 0.0000000000000000009363 87.0
SHD1_k127_4961904_6 Penicillin-binding protein K12555,K18770 - 2.4.1.129,3.4.16.4 0.00002833 54.0
SHD1_k127_4973382_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004381 251.0
SHD1_k127_4973382_1 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000001401 145.0
SHD1_k127_4973382_2 - - - - 0.0000000000000000001073 100.0
SHD1_k127_4973382_3 - - - - 0.000000000000001145 84.0
SHD1_k127_4978687_0 Histidine kinase - - - 1.099e-200 634.0
SHD1_k127_4978687_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 316.0
SHD1_k127_4978687_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 313.0
SHD1_k127_4978687_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000001372 155.0
SHD1_k127_4978687_4 - - - - 0.0000000000000000000000000000000000000005541 154.0
SHD1_k127_4988122_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 544.0
SHD1_k127_4988122_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity K13991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000001833 211.0
SHD1_k127_4992854_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.786e-287 889.0
SHD1_k127_4992854_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 284.0
SHD1_k127_4992854_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000008029 276.0
SHD1_k127_499414_0 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 476.0
SHD1_k127_499414_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 417.0
SHD1_k127_499414_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 363.0
SHD1_k127_499414_3 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 325.0
SHD1_k127_499414_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 300.0
SHD1_k127_499414_5 - - - - 0.00000000000000000000000000000000000000000000001791 179.0
SHD1_k127_499414_6 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000002217 127.0
SHD1_k127_499414_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000001693 72.0
SHD1_k127_5002902_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009297 280.0
SHD1_k127_5002902_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
SHD1_k127_5002902_2 Penicillinase repressor - - - 0.00000000000000000000001191 106.0
SHD1_k127_5002902_3 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000002387 102.0
SHD1_k127_5002902_4 Peptidase M56 - - - 0.000001061 60.0
SHD1_k127_501230_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 375.0
SHD1_k127_501230_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 353.0
SHD1_k127_501230_2 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 311.0
SHD1_k127_501230_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 284.0
SHD1_k127_501230_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000001717 194.0
SHD1_k127_501230_5 Cupin domain - - - 0.00000003838 61.0
SHD1_k127_502570_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1300.0
SHD1_k127_502570_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 472.0
SHD1_k127_502570_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 332.0
SHD1_k127_502570_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 332.0
SHD1_k127_502570_4 Rhomboid K19225 - 3.4.21.105 0.000000000000000000000000000000000000000868 159.0
SHD1_k127_502570_5 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000004592 121.0
SHD1_k127_5026810_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.004e-225 711.0
SHD1_k127_5026810_1 Pyridoxal-dependent decarboxylase conserved domain - - - 5.62e-212 670.0
SHD1_k127_5026810_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 6.379e-195 613.0
SHD1_k127_5026810_3 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 588.0
SHD1_k127_5026810_4 alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 324.0
SHD1_k127_5026810_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000009237 200.0
SHD1_k127_5026810_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001037 187.0
SHD1_k127_5026810_7 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000001021 174.0
SHD1_k127_5026810_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000004434 131.0
SHD1_k127_5028247_0 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 418.0
SHD1_k127_5028247_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000005975 264.0
SHD1_k127_5028247_2 Putative regulatory protein - - - 0.00000000000000006914 89.0
SHD1_k127_5049027_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.0 1653.0
SHD1_k127_5049027_1 Sortilin, neurotensin receptor 3, - - - 0.0 1342.0
SHD1_k127_5049027_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 538.0
SHD1_k127_5049027_3 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 430.0
SHD1_k127_5049027_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000009675 149.0
SHD1_k127_5049027_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000006261 131.0
SHD1_k127_5049027_7 Tetratricopeptide repeat - - - 0.00000000000000001087 89.0
SHD1_k127_5049027_8 Cytochrome c K00406,K08906 - - 0.00000001982 61.0
SHD1_k127_5069469_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 4.351e-318 993.0
SHD1_k127_5069469_1 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 591.0
SHD1_k127_5069469_2 - - - - 0.000000000000000000000000000000000000000000000001009 180.0
SHD1_k127_5069469_3 RNA recognition motif - - - 0.000000000000000000000000000000003518 130.0
SHD1_k127_5070384_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 473.0
SHD1_k127_5070384_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000002922 250.0
SHD1_k127_5070384_2 PFAM Aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000006741 230.0
SHD1_k127_5070384_3 - - - - 0.000001723 57.0
SHD1_k127_507282_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1339.0
SHD1_k127_507282_1 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 497.0
SHD1_k127_507282_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 434.0
SHD1_k127_5074502_0 von Willebrand factor (vWF) type A domain K07114 - - 1.556e-208 654.0
SHD1_k127_5074502_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 597.0
SHD1_k127_5074502_2 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 579.0
SHD1_k127_5074502_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 432.0
SHD1_k127_5074502_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 327.0
SHD1_k127_5074502_5 - K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 318.0
SHD1_k127_5074502_6 Histidine kinase K02482,K03557 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003332 232.0
SHD1_k127_5074502_7 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000001755 164.0
SHD1_k127_5074502_8 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000002088 75.0
SHD1_k127_5074502_9 Carboxypeptidase regulatory-like domain - - - 0.00000003321 63.0
SHD1_k127_5082562_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 408.0
SHD1_k127_5082562_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ - - - 0.000000000000000000000000000000000000000000000000000000000000000007069 232.0
SHD1_k127_5082562_2 Tetratricopeptide repeats K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000004263 152.0
SHD1_k127_5085916_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1682.0
SHD1_k127_5085916_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 503.0
SHD1_k127_5085916_2 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000009304 123.0
SHD1_k127_5100218_0 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 527.0
SHD1_k127_5104591_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 492.0
SHD1_k127_5104591_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
SHD1_k127_5104591_2 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002474 254.0
SHD1_k127_5104591_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000006433 211.0
SHD1_k127_5104591_4 DinB family - - - 0.000000000000000000000000000000000000000000000000003453 194.0
SHD1_k127_5104591_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000005886 156.0
SHD1_k127_5108810_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1023.0
SHD1_k127_5108810_1 PFAM Cytochrome c assembly protein K02198 - - 2.065e-309 960.0
SHD1_k127_5108810_2 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000002758 157.0
SHD1_k127_5108810_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000002636 128.0
SHD1_k127_5108810_4 - - - - 0.0000000000000000000001663 100.0
SHD1_k127_5108810_5 Protein of unknown function (DUF2934) - - - 0.0000621 48.0
SHD1_k127_5110083_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 7.569e-239 754.0
SHD1_k127_5110083_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000008587 131.0
SHD1_k127_5110184_0 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 386.0
SHD1_k127_5110184_1 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 327.0
SHD1_k127_5110184_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 288.0
SHD1_k127_5110184_3 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000001192 175.0
SHD1_k127_5110184_4 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000000000000000000000000000000000002485 153.0
SHD1_k127_5110184_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000004131 53.0
SHD1_k127_5120884_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.556e-251 786.0
SHD1_k127_5120884_1 Belongs to the GSP D family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001664 287.0
SHD1_k127_5120884_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001618 238.0
SHD1_k127_512735_0 GMC oxidoreductase - - - 2.205e-290 902.0
SHD1_k127_512735_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 523.0
SHD1_k127_512735_3 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 256.0
SHD1_k127_512735_4 Cytochrome c - - - 0.0000000000000000000000000000000000001268 151.0
SHD1_k127_512735_5 - - - - 0.00000000000002091 82.0
SHD1_k127_513049_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 612.0
SHD1_k127_513049_1 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000003889 210.0
SHD1_k127_513049_2 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000000000000000000000000000000001286 207.0
SHD1_k127_513049_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000002222 79.0
SHD1_k127_513049_4 - - - - 0.0004335 47.0
SHD1_k127_513049_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0005206 47.0
SHD1_k127_5155174_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 610.0
SHD1_k127_5155174_1 IMS family HHH motif K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 570.0
SHD1_k127_5155174_2 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 416.0
SHD1_k127_5155174_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 377.0
SHD1_k127_5155174_4 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 298.0
SHD1_k127_5155174_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
SHD1_k127_5155174_6 - - - - 0.0000000000000000007444 100.0
SHD1_k127_5161295_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 315.0
SHD1_k127_5161295_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002147 251.0
SHD1_k127_5161295_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000005503 219.0
SHD1_k127_5161295_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000003438 111.0
SHD1_k127_5161295_4 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000006324 86.0
SHD1_k127_5161295_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000002194 60.0
SHD1_k127_5168767_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.006e-225 707.0
SHD1_k127_5168767_1 Carbon starvation protein K06200 - - 7.442e-209 666.0
SHD1_k127_5168767_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 482.0
SHD1_k127_5168767_3 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 359.0
SHD1_k127_5168767_4 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000001468 210.0
SHD1_k127_5168767_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000645 162.0
SHD1_k127_5168767_6 MarR family - - - 0.000000000000000000000000000000000000001183 156.0
SHD1_k127_5168767_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000001425 70.0
SHD1_k127_5172233_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 400.0
SHD1_k127_5172233_1 Pfam:DUF1237 K09704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 351.0
SHD1_k127_5172233_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 347.0
SHD1_k127_518659_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 2.217e-227 718.0
SHD1_k127_518659_1 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 463.0
SHD1_k127_518659_2 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000004817 180.0
SHD1_k127_518659_3 Putative glucoamylase - - - 0.0000000000000000000000003117 105.0
SHD1_k127_5196791_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 603.0
SHD1_k127_5196791_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 599.0
SHD1_k127_5196791_2 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000002321 146.0
SHD1_k127_5196791_3 CAAX protease self-immunity K07052 - - 0.000000000000000000145 94.0
SHD1_k127_5196791_4 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000001868 78.0
SHD1_k127_5220539_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 505.0
SHD1_k127_5220539_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00138,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.000000000000000000000000000000000000000000000000000000000003412 213.0
SHD1_k127_5220539_2 Protein involved in outer membrane biogenesis K07289 - - 0.00000000000000000000000000000000000000000000001014 181.0
SHD1_k127_5239610_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 5.503e-215 680.0
SHD1_k127_5239610_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.327e-205 641.0
SHD1_k127_5239610_2 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 478.0
SHD1_k127_5239610_4 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000001847 226.0
SHD1_k127_5239610_5 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000009216 207.0
SHD1_k127_5239610_6 Enoyl-CoA hydratase K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000167 183.0
SHD1_k127_5239610_7 Beta-lactamase - - - 0.00005127 46.0
SHD1_k127_5254909_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1589.0
SHD1_k127_5254909_1 PFAM peptidase - - - 2.301e-245 764.0
SHD1_k127_5254909_10 YtxH-like protein - - - 0.0000000000000000000000000000001082 128.0
SHD1_k127_5254909_11 Aldo Keto reductase - - - 0.0000000789 55.0
SHD1_k127_5254909_2 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 470.0
SHD1_k127_5254909_3 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 325.0
SHD1_k127_5254909_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005433 257.0
SHD1_k127_5254909_5 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000002976 224.0
SHD1_k127_5254909_6 PFAM Colicin V production K03558 - - 0.00000000000000000000000000000000000000000000000000005481 192.0
SHD1_k127_5254909_7 - - - - 0.0000000000000000000000000000000000004265 147.0
SHD1_k127_5254909_8 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000004059 137.0
SHD1_k127_5254909_9 DinB superfamily - - - 0.000000000000000000000000000000000247 138.0
SHD1_k127_5258892_0 heat shock protein 70 K04043,K04044 - - 1.064e-306 949.0
SHD1_k127_5258892_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.522e-231 721.0
SHD1_k127_5258892_2 PFAM heat shock protein DnaJ K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 307.0
SHD1_k127_5258892_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003511 244.0
SHD1_k127_5258892_5 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000000000000000002814 196.0
SHD1_k127_5258892_6 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000002382 186.0
SHD1_k127_5258892_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000002978 190.0
SHD1_k127_5258892_8 FeS assembly protein IscX - - - 0.00000000000000000000000002872 109.0
SHD1_k127_5259655_0 Heat shock 70 kDa protein K04043 - - 0.0 1076.0
SHD1_k127_5259655_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
SHD1_k127_5259655_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
SHD1_k127_5259655_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001355 188.0
SHD1_k127_5259655_4 MerR HTH family regulatory protein K13640 - - 0.00000000000000000000000000000000000000000000000001534 182.0
SHD1_k127_5259655_5 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000006426 126.0
SHD1_k127_5266171_0 Aminotransferase class-III K00823 - 2.6.1.19 2.385e-223 701.0
SHD1_k127_5266171_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 7.346e-211 662.0
SHD1_k127_5266171_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 549.0
SHD1_k127_5266171_3 Protein of unknown function (DUF1440) - - - 0.0000000000000000000000000000007021 129.0
SHD1_k127_5266171_4 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000002138 120.0
SHD1_k127_5266171_5 - - - - 0.00000000000000214 82.0
SHD1_k127_527085_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 451.0
SHD1_k127_527085_1 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002243 248.0
SHD1_k127_527085_2 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000001873 192.0
SHD1_k127_527085_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000002082 133.0
SHD1_k127_5277296_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 5.045e-234 741.0
SHD1_k127_5277296_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 515.0
SHD1_k127_5277296_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 323.0
SHD1_k127_5277296_3 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000000000000001805 176.0
SHD1_k127_5277296_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000004954 60.0
SHD1_k127_5280232_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.805e-283 881.0
SHD1_k127_5280232_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 544.0
SHD1_k127_5280232_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 391.0
SHD1_k127_5280232_3 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
SHD1_k127_5280232_4 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 287.0
SHD1_k127_5280232_5 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000001744 223.0
SHD1_k127_5280232_6 - - - - 0.0000000000000000000000000000000000000000000000000036 190.0
SHD1_k127_5292449_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 590.0
SHD1_k127_5292449_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 362.0
SHD1_k127_5292449_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000002428 191.0
SHD1_k127_5292449_3 - - - - 0.00000000000000000000000000000000002252 141.0
SHD1_k127_5302301_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.044e-202 640.0
SHD1_k127_5302301_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.058e-196 623.0
SHD1_k127_5302301_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 495.0
SHD1_k127_5302301_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 481.0
SHD1_k127_5302301_4 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 463.0
SHD1_k127_5302301_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 398.0
SHD1_k127_5302301_6 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 355.0
SHD1_k127_5302301_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000003524 199.0
SHD1_k127_5311884_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 610.0
SHD1_k127_5311884_1 Dehydrogenase E1 component K00167,K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006181 266.0
SHD1_k127_5311884_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000004869 175.0
SHD1_k127_5311884_3 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000127 156.0
SHD1_k127_5311884_4 - - - - 0.0000000000000000000000004446 106.0
SHD1_k127_5315429_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 446.0
SHD1_k127_5315429_1 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000006963 133.0
SHD1_k127_5315429_2 cell redox homeostasis - - - 0.000000000000000000000000000001188 129.0
SHD1_k127_5315429_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000002165 124.0
SHD1_k127_5315429_4 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000005824 106.0
SHD1_k127_5315429_5 Belongs to the MraZ family K03925 - - 0.0000000000000000001971 88.0
SHD1_k127_5320142_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 591.0
SHD1_k127_5320142_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 499.0
SHD1_k127_5320142_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 302.0
SHD1_k127_5320142_3 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006261 237.0
SHD1_k127_5320142_4 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000008152 211.0
SHD1_k127_5320142_6 Thioesterase superfamily - - - 0.000000001638 65.0
SHD1_k127_5339921_0 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 8.897e-198 627.0
SHD1_k127_5339921_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 304.0
SHD1_k127_5339921_2 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000001902 258.0
SHD1_k127_5342323_0 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000006091 257.0
SHD1_k127_5342323_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002613 146.0
SHD1_k127_5354573_0 Zinc-binding dehydrogenase K02030,K03810 - - 0.0000000000000000000000000000000001247 135.0
SHD1_k127_5354573_1 FemAB family - - - 0.000000000000000000000000000000003049 138.0
SHD1_k127_5354573_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000001223 139.0
SHD1_k127_5377656_0 Voltage gated chloride channel K03281 - - 9.137e-194 621.0
SHD1_k127_5377656_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 587.0
SHD1_k127_5377656_2 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 415.0
SHD1_k127_5377656_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001033 250.0
SHD1_k127_5377656_4 amine dehydrogenase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000008375 228.0
SHD1_k127_5377656_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000003044 151.0
SHD1_k127_5378477_0 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 384.0
SHD1_k127_5378477_1 Ribosomal subunit interface protein K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 253.0
SHD1_k127_5399816_0 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 2.055e-204 642.0
SHD1_k127_5399816_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 6.841e-199 629.0
SHD1_k127_5399816_2 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 529.0
SHD1_k127_5399816_3 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 527.0
SHD1_k127_5399816_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 413.0
SHD1_k127_5399816_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 399.0
SHD1_k127_5399816_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 372.0
SHD1_k127_5399816_7 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 372.0
SHD1_k127_5399816_8 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 350.0
SHD1_k127_5399816_9 Involved in the tonB-independent uptake of proteins - - - 0.00000000000001389 87.0
SHD1_k127_5416296_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 318.0
SHD1_k127_5416296_1 Protein of unknown function (DUF3373) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 318.0
SHD1_k127_5416296_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 290.0
SHD1_k127_5416296_3 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 287.0
SHD1_k127_5416296_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000001767 170.0
SHD1_k127_5416296_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000001181 85.0
SHD1_k127_5441864_0 serine threonine protein kinase K12132 - 2.7.11.1 5.315e-233 752.0
SHD1_k127_5441864_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003181 295.0
SHD1_k127_5441864_10 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000006976 79.0
SHD1_k127_5441864_11 helix_turn_helix, Lux Regulon K07685 - - 0.0000000000008714 73.0
SHD1_k127_5441864_12 Iron-sulfur cluster-binding domain K06871 - - 0.00003999 49.0
SHD1_k127_5441864_2 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004677 273.0
SHD1_k127_5441864_3 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
SHD1_k127_5441864_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002468 233.0
SHD1_k127_5441864_5 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000005004 218.0
SHD1_k127_5441864_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000929 222.0
SHD1_k127_5441864_7 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000005968 123.0
SHD1_k127_5441864_8 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000001529 102.0
SHD1_k127_5441864_9 DNA integration - - - 0.0000000000000000000002202 110.0
SHD1_k127_5446067_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.677e-212 679.0
SHD1_k127_5446067_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000371 125.0
SHD1_k127_5446067_2 - - - - 0.0000000000000000000000004405 116.0
SHD1_k127_5446803_0 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 581.0
SHD1_k127_5446803_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 290.0
SHD1_k127_5446803_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000002717 162.0
SHD1_k127_5446803_3 - - - - 0.000000000000000000000000000000008297 135.0
SHD1_k127_5473497_0 Carboxypeptidase regulatory-like domain - - - 9.02e-218 712.0
SHD1_k127_5473497_1 RNA polymerase sigma-54 factor K03092 - - 4.048e-212 671.0
SHD1_k127_5473497_2 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000007412 175.0
SHD1_k127_5474435_0 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 316.0
SHD1_k127_5474435_1 - - - - 0.0000000000000000000000000000000000000000000000000003536 196.0
SHD1_k127_5474435_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000002884 188.0
SHD1_k127_5474435_3 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001474 149.0
SHD1_k127_5474435_4 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000006341 131.0
SHD1_k127_5483596_0 HD domain - - - 3.537e-233 734.0
SHD1_k127_5483596_1 TIGRFAM aspartate ammonia-lyase K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 456.0
SHD1_k127_5483596_2 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00000000000000000000000000000000000000000000000000000000000000000005044 237.0
SHD1_k127_5483596_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000005316 187.0
SHD1_k127_5483596_4 Frataxin-like domain K06202 - - 0.000000000000000000000000000000164 126.0
SHD1_k127_5492956_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 460.0
SHD1_k127_5492956_1 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
SHD1_k127_5494465_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1056.0
SHD1_k127_5494465_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 519.0
SHD1_k127_5494465_10 - - - - 0.0000000000000000000000000001717 118.0
SHD1_k127_5494465_11 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000009821 70.0
SHD1_k127_5494465_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 490.0
SHD1_k127_5494465_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 443.0
SHD1_k127_5494465_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 292.0
SHD1_k127_5494465_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000001289 196.0
SHD1_k127_5494465_6 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000000001632 181.0
SHD1_k127_5494465_7 - - - - 0.000000000000000000000000000000000000000000002517 174.0
SHD1_k127_5494465_8 Starch binding domain K01200 - 3.2.1.41 0.000000000000000000000000000000000429 143.0
SHD1_k127_5494465_9 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000813 123.0
SHD1_k127_5506542_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 350.0
SHD1_k127_5506542_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 342.0
SHD1_k127_5506542_2 GlcNAc-PI de-N-acetylase K22135 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002524 278.0
SHD1_k127_5506542_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000007865 227.0
SHD1_k127_5506542_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000376 172.0
SHD1_k127_5506542_6 Belongs to the UPF0109 family K06960 - - 0.00000000000003872 76.0
SHD1_k127_5507314_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 2.932e-319 999.0
SHD1_k127_5507314_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000002901 208.0
SHD1_k127_5507314_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000001426 182.0
SHD1_k127_5507314_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000003605 149.0
SHD1_k127_5507314_4 - - - - 0.000000000002113 72.0
SHD1_k127_5507314_5 Tetratricopeptide repeat - - - 0.000000005175 60.0
SHD1_k127_581385_0 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 533.0
SHD1_k127_581385_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 377.0
SHD1_k127_581385_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005282 271.0
SHD1_k127_581385_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
SHD1_k127_586446_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 1.181e-243 765.0
SHD1_k127_586446_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000513 267.0
SHD1_k127_586446_2 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000000002237 186.0
SHD1_k127_586446_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000004437 115.0
SHD1_k127_603567_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 587.0
SHD1_k127_603567_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 444.0
SHD1_k127_603567_2 peptidase dimerisation domain K01438 - 3.5.1.16 0.00007774 45.0
SHD1_k127_61783_0 Belongs to the transketolase family K00615 - 2.2.1.1 9.767e-315 975.0
SHD1_k127_61783_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 401.0
SHD1_k127_61783_10 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000005347 77.0
SHD1_k127_61783_2 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 327.0
SHD1_k127_61783_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000004375 219.0
SHD1_k127_61783_4 peroxiredoxin activity K01607,K03469 - 3.1.26.4,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000008375 214.0
SHD1_k127_61783_5 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000001904 212.0
SHD1_k127_61783_6 Vitamin K epoxide reductase - - - 0.000000000000000000000000000005335 123.0
SHD1_k127_61783_7 PilZ domain - - - 0.000000000000000000000000009198 112.0
SHD1_k127_61783_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000001516 101.0
SHD1_k127_618884_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.416e-207 656.0
SHD1_k127_618884_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 311.0
SHD1_k127_618884_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000004102 166.0
SHD1_k127_619323_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1115.0
SHD1_k127_619323_1 photoreceptor activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000008512 229.0
SHD1_k127_619323_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000001842 139.0
SHD1_k127_643529_0 RNA binding K06959 - - 0.0 1118.0
SHD1_k127_643529_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1086.0
SHD1_k127_643529_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000007893 186.0
SHD1_k127_643529_3 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000001465 171.0
SHD1_k127_649975_0 ABC transporter, transmembrane K18890 - - 1.354e-267 837.0
SHD1_k127_649975_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 623.0
SHD1_k127_649975_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 496.0
SHD1_k127_649975_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 390.0
SHD1_k127_649975_4 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 368.0
SHD1_k127_649975_5 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 328.0
SHD1_k127_65372_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000001785 200.0
SHD1_k127_65372_1 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000003755 158.0
SHD1_k127_65372_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000006493 151.0
SHD1_k127_65372_3 - - - - 0.0000000000000000000000000000000001477 136.0
SHD1_k127_65372_4 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.0000000000002203 80.0
SHD1_k127_684114_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 397.0
SHD1_k127_684114_1 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000004645 128.0
SHD1_k127_684114_4 - - - - 0.00000004774 55.0
SHD1_k127_684114_5 Bacterial transcriptional activator domain - - - 0.0002141 51.0
SHD1_k127_684559_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 354.0
SHD1_k127_684559_1 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 310.0
SHD1_k127_684559_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.000000000000000000000000000002317 133.0
SHD1_k127_684559_4 Cupin domain - - - 0.000000000000000000000000005858 113.0
SHD1_k127_687740_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 476.0
SHD1_k127_687740_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
SHD1_k127_687740_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000001963 201.0
SHD1_k127_687740_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000009908 152.0
SHD1_k127_697638_0 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 387.0
SHD1_k127_697638_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 385.0
SHD1_k127_697638_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 308.0
SHD1_k127_697638_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 296.0
SHD1_k127_697638_4 outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001083 274.0
SHD1_k127_697638_5 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 279.0
SHD1_k127_710696_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 616.0
SHD1_k127_710696_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 428.0
SHD1_k127_723454_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1032.0
SHD1_k127_723454_1 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 431.0
SHD1_k127_723454_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
SHD1_k127_723454_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000008876 117.0
SHD1_k127_723454_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.00000000000000000000000001195 110.0
SHD1_k127_723454_6 PFAM Mov34 MPN PAD-1 - - - 0.000001084 56.0
SHD1_k127_753204_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 465.0
SHD1_k127_753204_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 436.0
SHD1_k127_753204_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 410.0
SHD1_k127_753204_3 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 397.0
SHD1_k127_753204_4 Belongs to the acetokinase family K00929 - 2.7.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 366.0
SHD1_k127_753204_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 311.0
SHD1_k127_753204_6 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001933 263.0
SHD1_k127_753204_7 Transcriptional regulator, MerR family K00558,K13639,K13640 - 2.1.1.37 0.0000000000000000000000000001964 119.0
SHD1_k127_753204_8 Domain of unknown function (DUF4139) - - - 0.00001084 56.0
SHD1_k127_753204_9 Lamin Tail Domain - - - 0.0001021 52.0
SHD1_k127_76181_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 4.56e-246 766.0
SHD1_k127_76181_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 386.0
SHD1_k127_76181_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000112 194.0
SHD1_k127_76181_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000009564 122.0
SHD1_k127_762303_0 DEAD DEAH box helicase K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 463.0
SHD1_k127_762303_1 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000001508 93.0
SHD1_k127_762303_2 hydrolase of alkaline phosphatase superfamily K07014 - - 0.00000001466 68.0
SHD1_k127_763224_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000005561 250.0
SHD1_k127_763224_2 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001544 242.0
SHD1_k127_763224_3 BON domain - - - 0.00000000000000000000000000000000000000000000006275 176.0
SHD1_k127_763224_5 cheY-homologous receiver domain K07671 - - 0.00000000000000000000000000001864 121.0
SHD1_k127_763224_6 PAS domain - - - 0.00000000000000000001531 96.0
SHD1_k127_773177_0 Belongs to the ClpA ClpB family K03696 - - 7.662e-212 661.0
SHD1_k127_773177_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000006476 192.0
SHD1_k127_773177_2 Tetratricopeptide repeat - - - 0.0000000000000008605 83.0
SHD1_k127_81215_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 545.0
SHD1_k127_81215_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 430.0
SHD1_k127_81215_2 PFAM Ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 431.0
SHD1_k127_81215_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000002147 236.0
SHD1_k127_81215_4 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000004306 143.0
SHD1_k127_816919_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 449.0
SHD1_k127_816919_1 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 425.0
SHD1_k127_816919_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 429.0
SHD1_k127_816919_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 422.0
SHD1_k127_816919_4 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000007914 198.0
SHD1_k127_820285_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 523.0
SHD1_k127_820285_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 477.0
SHD1_k127_820285_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 445.0
SHD1_k127_820285_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 392.0
SHD1_k127_820285_4 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 305.0
SHD1_k127_820285_5 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 281.0
SHD1_k127_820285_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000006781 158.0
SHD1_k127_820285_7 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.00000000000000000000000000000000005417 138.0
SHD1_k127_820946_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.734e-204 644.0
SHD1_k127_820946_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 586.0
SHD1_k127_820946_2 ATPases associated with a variety of cellular activities K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
SHD1_k127_820946_3 - - - - 0.000000000000000000000003917 111.0
SHD1_k127_820946_6 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0003852 45.0
SHD1_k127_825056_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.516e-247 774.0
SHD1_k127_825056_1 TatD related DNase K03424 - - 0.000006792 48.0
SHD1_k127_838897_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 411.0
SHD1_k127_838897_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 337.0
SHD1_k127_838897_2 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 304.0
SHD1_k127_838897_3 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000002564 152.0
SHD1_k127_838897_4 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000004518 139.0
SHD1_k127_868147_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 328.0
SHD1_k127_868147_1 Protein involved in outer membrane biogenesis K07289,K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 310.0
SHD1_k127_868147_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000002624 168.0
SHD1_k127_868147_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000001433 149.0
SHD1_k127_868147_4 Prokaryotic N-terminal methylation motif K02650,K02679,K10926,K12285 - - 0.000000000000000000000000000000003941 133.0
SHD1_k127_868147_6 - - - - 0.0000000000000002716 81.0
SHD1_k127_902004_0 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000002103 238.0
SHD1_k127_902004_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000214 190.0
SHD1_k127_902004_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000003267 84.0
SHD1_k127_902004_3 response regulator, receiver - - - 0.000000000001429 73.0
SHD1_k127_902004_4 helix_turn_helix, Lux Regulon - - - 0.000001289 53.0
SHD1_k127_915077_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000001041 220.0
SHD1_k127_915077_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000001703 208.0
SHD1_k127_915077_2 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.00000000000000000000000000000000000000000001535 167.0
SHD1_k127_916827_0 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 282.0
SHD1_k127_916827_1 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000000000000000000000003453 210.0
SHD1_k127_916827_2 - - - - 0.0000000000000000000000000002476 117.0
SHD1_k127_916827_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000367 78.0
SHD1_k127_925645_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 381.0
SHD1_k127_925645_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 286.0
SHD1_k127_928433_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 419.0
SHD1_k127_928433_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 387.0
SHD1_k127_928433_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000008547 191.0
SHD1_k127_928433_3 Patatin-like phospholipase K07001 - - 0.000002064 51.0
SHD1_k127_945252_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 5.018e-217 689.0
SHD1_k127_945252_1 phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 605.0
SHD1_k127_945252_10 RDD family - - - 0.000000000000000000000008154 108.0
SHD1_k127_945252_11 Helix-hairpin-helix motif - - - 0.00000000000000000000002617 104.0
SHD1_k127_945252_12 COG0457 FOG TPR repeat - - - 0.000000002132 70.0
SHD1_k127_945252_2 lipopolysaccharide transport K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 569.0
SHD1_k127_945252_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 394.0
SHD1_k127_945252_4 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 335.0
SHD1_k127_945252_5 - - - - 0.00000000000000000000000000000000000000000000000000000009625 198.0
SHD1_k127_945252_6 RDD family - - - 0.0000000000000000000000000000000000000001151 158.0
SHD1_k127_945252_7 Cold shock protein domain K03704 - - 0.00000000000000000000000000000003007 126.0
SHD1_k127_945252_8 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000000002315 127.0
SHD1_k127_945252_9 Protein of unknown function (DUF507) K09804 - - 0.00000000000000000000000004253 109.0
SHD1_k127_946854_0 Dienelactone hydrolase family - - - 1.206e-245 776.0
SHD1_k127_946854_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 469.0
SHD1_k127_946854_2 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000004302 237.0
SHD1_k127_946854_3 response to heat K07090 - - 0.0000000000000000000000000000000000009586 142.0
SHD1_k127_947928_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1102.0
SHD1_k127_947928_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 488.0
SHD1_k127_947928_2 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000003632 245.0
SHD1_k127_947928_3 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000000000000000000000000001191 164.0
SHD1_k127_947928_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000304 126.0
SHD1_k127_947928_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03665 - - 0.000001856 54.0
SHD1_k127_947928_7 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - - - 0.0005415 49.0
SHD1_k127_954193_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 402.0
SHD1_k127_954193_1 PFAM Peptidase M20 K01439 - 3.5.1.18 0.00000000000000001889 88.0
SHD1_k127_954193_2 Universal stress protein - - - 0.00000000002022 74.0
SHD1_k127_972662_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 381.0
SHD1_k127_972662_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000008129 237.0
SHD1_k127_972662_2 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000007998 158.0
SHD1_k127_979073_0 PFAM TonB-dependent Receptor Plug - - - 4.538e-231 753.0
SHD1_k127_979073_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 516.0
SHD1_k127_979073_2 ethanolamine kinase activity K07251 - 2.7.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 367.0
SHD1_k127_979073_3 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 316.0
SHD1_k127_979073_4 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 298.0
SHD1_k127_979073_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000003679 201.0
SHD1_k127_979073_6 - - - - 0.00000000000000000000000000000001048 130.0
SHD1_k127_979120_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 7.379e-297 920.0
SHD1_k127_979120_1 Transcriptional - - - 0.000000000000000000000000005278 112.0
SHD1_k127_979120_2 Helix-hairpin-helix motif - - - 0.00000000000000000000003992 111.0
SHD1_k127_979120_3 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000003858 98.0
SHD1_k127_979120_4 - - - - 0.00000000000001676 76.0
SHD1_k127_979120_5 DNA uptake protein and related DNA-binding K02237 - - 0.000004589 58.0
SHD1_k127_981004_0 Ku70/Ku80 beta-barrel domain K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 366.0
SHD1_k127_981004_1 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 330.0
SHD1_k127_981004_2 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002792 266.0
SHD1_k127_981004_3 Chemotaxis phosphatase CheX K03409 - - 0.000000000000000000000000000000000000000000000000000000000000000009171 229.0
SHD1_k127_981004_4 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000003856 146.0
SHD1_k127_981004_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000001422 142.0
SHD1_k127_981004_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000001024 60.0
SHD1_k127_987378_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 599.0
SHD1_k127_987378_1 PFAM aminotransferase class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 543.0
SHD1_k127_987378_2 Phosphoesterase family - - - 0.00000003997 59.0
SHD1_k127_989525_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1387.0
SHD1_k127_989525_1 radical SAM domain protein K22318 - - 2.022e-217 681.0
SHD1_k127_989525_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 296.0
SHD1_k127_989525_3 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002619 266.0
SHD1_k127_989525_4 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
SHD1_k127_989525_5 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000008557 175.0
SHD1_k127_989525_6 - - - - 0.000000000000000000000000000000007578 132.0
SHD1_k127_989525_7 - - - - 0.00000000000000000000000000001116 119.0
SHD1_k127_989525_8 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000007448 117.0
SHD1_k127_989525_9 Helix-hairpin-helix motif - - - 0.00000000000000000003778 96.0
SHD1_k127_992487_0 Belongs to the TPP enzyme family K00156 - 1.2.5.1 3.513e-267 834.0
SHD1_k127_992487_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 4.79e-209 689.0
SHD1_k127_992487_2 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 606.0
SHD1_k127_992487_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 396.0
SHD1_k127_992487_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000008111 100.0
SHD1_k127_992487_5 aminopeptidase activity - - - 0.000000000000001236 91.0
SHD1_k127_992487_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000008018 62.0
SHD1_k127_992487_7 Cysteine-rich secretory protein family - - - 0.00000197 61.0
SHD1_k127_998126_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 2.448e-209 666.0
SHD1_k127_998126_1 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 304.0
SHD1_k127_998126_2 - - - - 0.00000000000000000000000000000000000000000000004111 179.0
SHD1_k127_998126_3 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000137 128.0
SHD1_k127_998126_4 - - - - 0.0000000000000000000000000008812 119.0
SHD1_k127_998126_6 CsbD-like - - - 0.000000000000003285 78.0
SHD1_k127_998126_7 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000004975 75.0