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Overview

ID MAG03366
Name SHD1_bin.3
Sample SMP0082
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Casimicrobiaceae
Genus PALSA-1003
Species
Assembly information
Completeness (%) 63.77
Contamination (%) 0.27
GC content (%) 65.0
N50 (bp) 9,470
Genome size (bp) 1,904,932

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1831

Gene name Description KEGG GOs EC E-value Score Sequence
SHD1_k127_1012993_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 1.832e-242 766.0
SHD1_k127_1012993_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 542.0
SHD1_k127_1012993_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 524.0
SHD1_k127_1012993_3 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 410.0
SHD1_k127_1012993_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 346.0
SHD1_k127_1012993_5 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 346.0
SHD1_k127_1012993_6 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004611 284.0
SHD1_k127_1012993_7 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000298 209.0
SHD1_k127_1012993_8 COG3245 Cytochrome c5 - - - 0.00000000000000000000000000000000000000000001151 174.0
SHD1_k127_1012993_9 Sulfotransferase family - - - 0.000000006016 66.0
SHD1_k127_1019101_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 592.0
SHD1_k127_1019101_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 476.0
SHD1_k127_1019101_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 317.0
SHD1_k127_1019101_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000001992 219.0
SHD1_k127_1042272_0 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 419.0
SHD1_k127_1042272_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002693 246.0
SHD1_k127_1042272_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000002441 234.0
SHD1_k127_1042272_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000002075 184.0
SHD1_k127_1042272_4 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.00000009658 61.0
SHD1_k127_1060584_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 3.016e-306 958.0
SHD1_k127_1060584_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 554.0
SHD1_k127_1060584_10 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008569 288.0
SHD1_k127_1060584_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000009751 261.0
SHD1_k127_1060584_12 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000001885 261.0
SHD1_k127_1060584_13 MOSC domain protein beta barrel domain protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000003718 239.0
SHD1_k127_1060584_14 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000006867 218.0
SHD1_k127_1060584_15 Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
SHD1_k127_1060584_16 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000000000005946 209.0
SHD1_k127_1060584_17 mRNA catabolic process - - - 0.00000000000000000000000003656 115.0
SHD1_k127_1060584_2 Type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 482.0
SHD1_k127_1060584_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 483.0
SHD1_k127_1060584_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 449.0
SHD1_k127_1060584_5 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 414.0
SHD1_k127_1060584_6 PFAM NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 400.0
SHD1_k127_1060584_7 type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 370.0
SHD1_k127_1060584_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 321.0
SHD1_k127_1060584_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 324.0
SHD1_k127_1062864_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 512.0
SHD1_k127_1062864_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 397.0
SHD1_k127_1062864_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 332.0
SHD1_k127_1062864_3 cobalamin biosynthetic process K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 323.0
SHD1_k127_1062864_4 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 316.0
SHD1_k127_1062864_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 306.0
SHD1_k127_1062864_6 tellurite resistance protein - - - 0.00000000000000000000000000000000000000000000000000001317 195.0
SHD1_k127_1062864_7 Protein of unknown function (DUF2917) - - - 0.00006841 50.0
SHD1_k127_1064760_0 MgsA AAA+ ATPase C terminal K07478 - - 7.494e-200 632.0
SHD1_k127_1064760_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 603.0
SHD1_k127_1064760_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 339.0
SHD1_k127_1064760_3 DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 319.0
SHD1_k127_1064760_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000073 136.0
SHD1_k127_1087233_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.041e-195 619.0
SHD1_k127_1087233_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 509.0
SHD1_k127_1087233_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 350.0
SHD1_k127_1087233_3 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 314.0
SHD1_k127_1087233_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003147 249.0
SHD1_k127_1087233_5 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000013 186.0
SHD1_k127_1087233_6 Nuclear protein SET K07117 - - 0.00000000000000000000000000000000000000000003637 166.0
SHD1_k127_1090057_0 PFAM NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1140.0
SHD1_k127_1090057_1 PFAM AMP-dependent synthetase and ligase K08295 - 6.2.1.32 6.711e-244 764.0
SHD1_k127_1090057_2 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 333.0
SHD1_k127_1090057_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
SHD1_k127_1090057_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000007108 187.0
SHD1_k127_1090057_5 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000000001548 186.0
SHD1_k127_1090057_6 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000006277 172.0
SHD1_k127_1092482_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 3.45e-222 693.0
SHD1_k127_1092482_1 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 351.0
SHD1_k127_1092482_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002744 243.0
SHD1_k127_1092482_3 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
SHD1_k127_1092482_4 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000003748 166.0
SHD1_k127_1092482_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000001614 62.0
SHD1_k127_1093638_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 473.0
SHD1_k127_1093638_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 404.0
SHD1_k127_1093638_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 308.0
SHD1_k127_1093638_3 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 316.0
SHD1_k127_1105141_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 3.715e-236 739.0
SHD1_k127_1105141_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002176 287.0
SHD1_k127_1105141_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003506 282.0
SHD1_k127_1105141_3 Isochorismatase family - - - 0.000000000000000000000000000000000000000000001562 170.0
SHD1_k127_1105141_4 Thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000002104 159.0
SHD1_k127_1110134_0 Cytochrome C oxidase accessory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 419.0
SHD1_k127_1110134_1 CRP FNR family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004768 291.0
SHD1_k127_1110134_2 FixH family K09926 - - 0.0000000000000000000000005395 112.0
SHD1_k127_1110134_3 - - - - 0.00000000000000000002414 94.0
SHD1_k127_1110134_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000007046 90.0
SHD1_k127_1138322_0 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 540.0
SHD1_k127_1138322_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 422.0
SHD1_k127_1138322_2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 413.0
SHD1_k127_1138322_3 FAD binding domain K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 317.0
SHD1_k127_1138322_4 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000000000000000000000000000000000000001382 150.0
SHD1_k127_1138322_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000005986 138.0
SHD1_k127_1170338_0 Histidine kinase-like ATPases - - - 3.561e-270 858.0
SHD1_k127_1170338_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 430.0
SHD1_k127_1170338_2 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 319.0
SHD1_k127_1170338_3 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 294.0
SHD1_k127_1170338_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000003296 193.0
SHD1_k127_1170338_5 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000002909 118.0
SHD1_k127_1170338_6 Histidine kinase K20976 - - 0.00000000000000000000002641 108.0
SHD1_k127_1170338_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000001094 83.0
SHD1_k127_1173850_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1372.0
SHD1_k127_1173850_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.477e-260 808.0
SHD1_k127_1173850_2 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 7.487e-200 631.0
SHD1_k127_1173850_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 411.0
SHD1_k127_1173850_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 343.0
SHD1_k127_1173850_5 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001606 271.0
SHD1_k127_1173850_6 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000188 227.0
SHD1_k127_1173850_7 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000001454 127.0
SHD1_k127_1173850_8 Protein of unknown function (DUF4019) - - - 0.00000000000005927 85.0
SHD1_k127_1193369_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 526.0
SHD1_k127_1193369_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 420.0
SHD1_k127_1193369_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 427.0
SHD1_k127_1193369_3 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 370.0
SHD1_k127_1193369_4 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
SHD1_k127_1193369_5 Carboxymuconolactone decarboxylase family protein 2 - - - 0.00000000000000000000000000000000000000000000000000000000004057 211.0
SHD1_k127_1193369_6 Bacterial SH3 domain homologues - - - 0.00000000000000000000000000000000000000000003076 173.0
SHD1_k127_1193369_7 Protein conserved in bacteria - - - 0.00000000000000000000000000191 116.0
SHD1_k127_1193369_8 STAS domain K06378 - - 0.000000000000000003233 89.0
SHD1_k127_1220724_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.272e-206 649.0
SHD1_k127_1220724_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 547.0
SHD1_k127_1220724_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000002413 143.0
SHD1_k127_1220724_11 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000003769 137.0
SHD1_k127_1220724_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000001574 108.0
SHD1_k127_1220724_13 Putative prokaryotic signal transducing protein - - - 0.00000000000000000003592 93.0
SHD1_k127_1220724_14 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001783 79.0
SHD1_k127_1220724_2 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 461.0
SHD1_k127_1220724_3 epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 406.0
SHD1_k127_1220724_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 317.0
SHD1_k127_1220724_5 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006355 260.0
SHD1_k127_1220724_6 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000000001931 213.0
SHD1_k127_1220724_7 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
SHD1_k127_1220724_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000009875 191.0
SHD1_k127_1220724_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000001326 131.0
SHD1_k127_1298548_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 7.928e-240 755.0
SHD1_k127_1298548_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 439.0
SHD1_k127_1298548_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000001151 205.0
SHD1_k127_1298548_3 atpase or kinase K06925 - - 0.000000000000000000000000000000000000000006961 161.0
SHD1_k127_1298548_4 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000006881 164.0
SHD1_k127_1298548_5 - - - - 0.0000000000000000000000005263 121.0
SHD1_k127_1298548_6 - - - - 0.00000000000000000007842 97.0
SHD1_k127_1321984_0 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 587.0
SHD1_k127_1321984_1 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 540.0
SHD1_k127_1321984_2 abc transporter K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 465.0
SHD1_k127_1321984_3 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 426.0
SHD1_k127_1321984_4 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 419.0
SHD1_k127_1321984_5 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000005925 162.0
SHD1_k127_134295_0 Helicase K03722 - 3.6.4.12 1.079e-251 791.0
SHD1_k127_134295_1 Psort location Cytoplasmic, score 8.96 K07462 - - 6.793e-214 677.0
SHD1_k127_134295_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000001797 139.0
SHD1_k127_134295_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 538.0
SHD1_k127_134295_3 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 446.0
SHD1_k127_134295_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 384.0
SHD1_k127_134295_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 364.0
SHD1_k127_134295_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 340.0
SHD1_k127_134295_7 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 237.0
SHD1_k127_134295_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000001728 229.0
SHD1_k127_134295_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000004529 208.0
SHD1_k127_1382207_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1210.0
SHD1_k127_1382207_1 Helicase K03657 - 3.6.4.12 4.185e-299 936.0
SHD1_k127_1382207_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000003035 148.0
SHD1_k127_1382207_11 Protein of unknown function (DUF2782) - - - 0.000000000000000000000001886 106.0
SHD1_k127_1382207_12 - - - - 0.000000000000000000000003121 115.0
SHD1_k127_1382207_13 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000009342 97.0
SHD1_k127_1382207_14 - - - - 0.0000000000000000001381 96.0
SHD1_k127_1382207_15 protein conserved in bacteria - - - 0.000003682 60.0
SHD1_k127_1382207_16 Zn-finger domain associated with topoisomerase type I - - - 0.00004097 53.0
SHD1_k127_1382207_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.7e-285 884.0
SHD1_k127_1382207_3 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 549.0
SHD1_k127_1382207_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 429.0
SHD1_k127_1382207_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 335.0
SHD1_k127_1382207_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 328.0
SHD1_k127_1382207_7 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000004162 214.0
SHD1_k127_1382207_8 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000115 166.0
SHD1_k127_1382207_9 - - - - 0.0000000000000000000000000000000000000000000365 171.0
SHD1_k127_1411040_0 protein conserved in bacteria K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 537.0
SHD1_k127_1411040_1 ATPase (AAA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 486.0
SHD1_k127_1411040_10 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000004677 87.0
SHD1_k127_1411040_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 403.0
SHD1_k127_1411040_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 302.0
SHD1_k127_1411040_4 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 302.0
SHD1_k127_1411040_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 299.0
SHD1_k127_1411040_6 AzlC protein - - - 0.000000000000000000000000000000000000000000000000002975 190.0
SHD1_k127_1411040_7 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000043 153.0
SHD1_k127_1411040_8 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000008582 136.0
SHD1_k127_1411040_9 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000158 108.0
SHD1_k127_1433516_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 334.0
SHD1_k127_1433516_1 KR domain K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 290.0
SHD1_k127_1433516_2 ChrR Cupin-like domain K05913 - 1.13.11.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000112 268.0
SHD1_k127_1433516_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
SHD1_k127_1433516_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000003008 167.0
SHD1_k127_1433516_5 COGs COG4087 Soluble P-type ATPase - - - 0.0000000000000000000000000000000000000000009504 161.0
SHD1_k127_1433516_6 Uncharacterized ACR, COG1993 - - - 0.00000000000000000000000000000000005417 138.0
SHD1_k127_1465318_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.561e-305 944.0
SHD1_k127_1465318_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 535.0
SHD1_k127_1465318_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 463.0
SHD1_k127_1465318_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 429.0
SHD1_k127_1465318_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 294.0
SHD1_k127_1465318_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000361 246.0
SHD1_k127_1465318_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000003727 162.0
SHD1_k127_1465318_7 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000001387 91.0
SHD1_k127_1465318_8 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000317 64.0
SHD1_k127_1490337_0 Belongs to the ABC transporter superfamily K02031,K02032,K13892,K13896 - - 8.689e-265 839.0
SHD1_k127_1490337_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 7.78e-217 689.0
SHD1_k127_1490337_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 516.0
SHD1_k127_1490337_3 PFAM extracellular solute-binding protein, family 5 K02035,K13889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 404.0
SHD1_k127_1490337_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 383.0
SHD1_k127_1490337_5 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 323.0
SHD1_k127_1490337_6 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003936 249.0
SHD1_k127_149068_0 Flp pilus assembly protein, ATPase CpaF K02283 - - 3.182e-288 891.0
SHD1_k127_149068_1 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 432.0
SHD1_k127_149068_2 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 325.0
SHD1_k127_149068_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002276 234.0
SHD1_k127_149068_4 - - - - 0.000000002298 70.0
SHD1_k127_1522045_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 2.993e-266 846.0
SHD1_k127_1522045_1 topoisomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 421.0
SHD1_k127_1522045_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001171 260.0
SHD1_k127_1522045_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000003227 89.0
SHD1_k127_1562534_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 4.437e-273 849.0
SHD1_k127_1562534_1 PFAM extracellular solute-binding protein family 1 K02027 - - 3.289e-240 749.0
SHD1_k127_1562534_10 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001817 267.0
SHD1_k127_1562534_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000002254 237.0
SHD1_k127_1562534_12 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000001308 213.0
SHD1_k127_1562534_13 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000434 181.0
SHD1_k127_1562534_14 OsmC-like protein K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.000000000000000000000000000000000000000000000003944 178.0
SHD1_k127_1562534_15 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.0000000000000000000000000000000000000474 154.0
SHD1_k127_1562534_2 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 4.524e-202 634.0
SHD1_k127_1562534_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 516.0
SHD1_k127_1562534_4 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 519.0
SHD1_k127_1562534_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 490.0
SHD1_k127_1562534_6 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 475.0
SHD1_k127_1562534_7 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 306.0
SHD1_k127_1562534_8 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 293.0
SHD1_k127_1562534_9 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004029 271.0
SHD1_k127_1567120_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 9.762e-208 650.0
SHD1_k127_1567120_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 581.0
SHD1_k127_1567120_10 protein conserved in bacteria K09984 - - 0.000000000000000000227 89.0
SHD1_k127_1567120_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 511.0
SHD1_k127_1567120_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009079 278.0
SHD1_k127_1567120_4 Threonine transporter RhtB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002942 248.0
SHD1_k127_1567120_5 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000005731 233.0
SHD1_k127_1567120_6 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000002833 220.0
SHD1_k127_1567120_7 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000001407 193.0
SHD1_k127_1567120_8 transcriptional - - - 0.000000000000000000000000000000000003396 142.0
SHD1_k127_1567120_9 carboxylase K01969 - 6.4.1.4 0.00000000000000000000000000001081 122.0
SHD1_k127_1571919_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 583.0
SHD1_k127_1571919_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 525.0
SHD1_k127_1571919_2 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 509.0
SHD1_k127_1571919_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 420.0
SHD1_k127_1571919_4 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 317.0
SHD1_k127_1571919_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000008724 150.0
SHD1_k127_1571919_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000009366 122.0
SHD1_k127_1575300_0 ABC-type sugar transport system periplasmic component K02027,K05813 - - 6.219e-212 664.0
SHD1_k127_1575300_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.723e-206 652.0
SHD1_k127_1575300_10 Aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 366.0
SHD1_k127_1575300_11 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 339.0
SHD1_k127_1575300_12 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 320.0
SHD1_k127_1575300_13 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
SHD1_k127_1575300_14 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 298.0
SHD1_k127_1575300_15 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
SHD1_k127_1575300_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
SHD1_k127_1575300_17 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000004605 236.0
SHD1_k127_1575300_18 ApaG domain - - - 0.00000000000000000000000000000000000000000000000000007198 192.0
SHD1_k127_1575300_19 Flavin reductase like domain K16048 - - 0.0000000000000000000000000000000000000000000000007828 180.0
SHD1_k127_1575300_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 529.0
SHD1_k127_1575300_20 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000004448 145.0
SHD1_k127_1575300_21 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000003005 129.0
SHD1_k127_1575300_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 515.0
SHD1_k127_1575300_4 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 456.0
SHD1_k127_1575300_5 ABC-type sugar transport systems permease components K02025,K05814,K10118,K17242,K17245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 445.0
SHD1_k127_1575300_6 Binding-protein-dependent transport system inner membrane component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 432.0
SHD1_k127_1575300_7 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 423.0
SHD1_k127_1575300_8 membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 418.0
SHD1_k127_1575300_9 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 408.0
SHD1_k127_158509_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.273e-226 712.0
SHD1_k127_158509_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 443.0
SHD1_k127_158509_2 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000007926 222.0
SHD1_k127_158509_3 RESPONSE REGULATOR receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002547 190.0
SHD1_k127_158509_4 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000000000000000000000001365 189.0
SHD1_k127_158509_5 CheW-like domain K02659 - - 0.00000000000000000000000000000000001108 141.0
SHD1_k127_158509_6 chemotaxis K02660 - - 0.00000002354 62.0
SHD1_k127_158509_7 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000004169 56.0
SHD1_k127_1611149_0 Aminotransferase K14261 - - 1.41e-207 651.0
SHD1_k127_1611149_1 Homoserine dehydrogenase K00003 - 1.1.1.3 4.281e-197 642.0
SHD1_k127_1611149_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 374.0
SHD1_k127_1611149_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002357 251.0
SHD1_k127_1611149_4 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000001174 246.0
SHD1_k127_1611149_5 plastoquinol--plastocyanin reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
SHD1_k127_1611149_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000009163 142.0
SHD1_k127_1611149_7 Bacterial PH domain - - - 0.000000000000000000000000000000008756 134.0
SHD1_k127_1611149_8 Sulfotransferase family - - - 0.000103 53.0
SHD1_k127_1616858_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1211.0
SHD1_k127_1616858_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 522.0
SHD1_k127_1616858_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 419.0
SHD1_k127_1616858_3 peptidase K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 316.0
SHD1_k127_1616858_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000306 151.0
SHD1_k127_1616858_5 Protein of unknown function (DUF721) - - - 0.0001817 53.0
SHD1_k127_1619036_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.102e-291 906.0
SHD1_k127_1619036_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.987e-208 660.0
SHD1_k127_1619036_10 -acetyltransferase - - - 0.0000000000000000000000000000000000000000003202 162.0
SHD1_k127_1619036_11 Membrane - - - 0.0000000000000000000000000000000000003296 145.0
SHD1_k127_1619036_12 Domain of unknown function (DUF1850) - - - 0.00000000000000000000000000005483 136.0
SHD1_k127_1619036_13 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000001944 102.0
SHD1_k127_1619036_2 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 590.0
SHD1_k127_1619036_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 572.0
SHD1_k127_1619036_4 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 486.0
SHD1_k127_1619036_5 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 457.0
SHD1_k127_1619036_6 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 401.0
SHD1_k127_1619036_7 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 294.0
SHD1_k127_1619036_8 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002343 278.0
SHD1_k127_1619036_9 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003619 262.0
SHD1_k127_163681_0 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 611.0
SHD1_k127_163681_1 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
SHD1_k127_163681_2 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004691 267.0
SHD1_k127_163681_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007161 254.0
SHD1_k127_1638150_0 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 600.0
SHD1_k127_1638150_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 506.0
SHD1_k127_1638150_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 453.0
SHD1_k127_1638150_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 363.0
SHD1_k127_1638150_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 305.0
SHD1_k127_1638150_5 Peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 299.0
SHD1_k127_1638150_6 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000002086 187.0
SHD1_k127_1653808_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 546.0
SHD1_k127_1653808_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 543.0
SHD1_k127_1653808_2 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
SHD1_k127_1653808_3 Protein of unknown function (DUF1282) - - - 0.000000000000000000000000000000000000000000000000000000000000000004085 244.0
SHD1_k127_1653808_4 - - - - 0.000000001412 64.0
SHD1_k127_1658478_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.422e-259 818.0
SHD1_k127_1658478_1 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 1.144e-226 713.0
SHD1_k127_1658478_10 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000002749 73.0
SHD1_k127_1658478_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 537.0
SHD1_k127_1658478_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 511.0
SHD1_k127_1658478_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 458.0
SHD1_k127_1658478_5 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 452.0
SHD1_k127_1658478_6 Histidine kinase K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 429.0
SHD1_k127_1658478_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 399.0
SHD1_k127_1658478_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 325.0
SHD1_k127_1658478_9 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000006341 111.0
SHD1_k127_1702963_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000002473 266.0
SHD1_k127_1702963_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
SHD1_k127_1702963_2 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001291 218.0
SHD1_k127_1702963_3 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000003157 180.0
SHD1_k127_1702963_4 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000002219 83.0
SHD1_k127_1709264_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 8.194e-210 665.0
SHD1_k127_1709264_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 381.0
SHD1_k127_1709264_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 362.0
SHD1_k127_1709264_3 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 322.0
SHD1_k127_1709264_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 295.0
SHD1_k127_1709264_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001026 278.0
SHD1_k127_1709264_6 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003912 263.0
SHD1_k127_1723346_0 N-terminal domain of (some) glycogen debranching enzymes - - - 7.778e-253 802.0
SHD1_k127_1723346_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003224 286.0
SHD1_k127_1723346_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000001068 171.0
SHD1_k127_1744468_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 334.0
SHD1_k127_1744468_1 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008893 251.0
SHD1_k127_1744468_2 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000007477 240.0
SHD1_k127_1744468_3 transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000009832 187.0
SHD1_k127_1744468_4 S4 RNA-binding domain K04762 - - 0.00000000000000289 85.0
SHD1_k127_1744468_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000002176 73.0
SHD1_k127_1745612_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 453.0
SHD1_k127_1745612_1 Belongs to the IlvD Edd family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 383.0
SHD1_k127_1745612_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 301.0
SHD1_k127_1745612_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000008577 216.0
SHD1_k127_1745612_4 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000001923 169.0
SHD1_k127_1745612_5 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000002174 136.0
SHD1_k127_1745612_6 CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000005272 128.0
SHD1_k127_1745612_7 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.0000000000005012 75.0
SHD1_k127_1775625_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 533.0
SHD1_k127_1775625_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 376.0
SHD1_k127_1775625_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 346.0
SHD1_k127_1775625_3 ATPases associated with a variety of cellular activities - - - 0.000007034 51.0
SHD1_k127_1775625_4 Pkd domain containing protein - - - 0.0008668 42.0
SHD1_k127_180052_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 372.0
SHD1_k127_180052_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001376 241.0
SHD1_k127_180052_2 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000001245 198.0
SHD1_k127_1802096_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 494.0
SHD1_k127_1802096_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000479 185.0
SHD1_k127_1802096_2 Cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000006052 182.0
SHD1_k127_1802096_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000002936 162.0
SHD1_k127_1802096_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000004114 119.0
SHD1_k127_1828336_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 584.0
SHD1_k127_1828336_1 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 414.0
SHD1_k127_1828336_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 403.0
SHD1_k127_1828336_3 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 317.0
SHD1_k127_1828336_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
SHD1_k127_1828336_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004675 273.0
SHD1_k127_1828336_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009518 265.0
SHD1_k127_1828336_7 integral membrane protein K02221 - - 0.0000000000000000000000000000000000000000008937 163.0
SHD1_k127_1828336_8 DUF167 K09131 - - 0.000000000000000000005085 96.0
SHD1_k127_1853155_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.43e-222 702.0
SHD1_k127_1853155_1 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 495.0
SHD1_k127_1853155_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 408.0
SHD1_k127_1853155_3 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 410.0
SHD1_k127_1853155_4 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 368.0
SHD1_k127_1853155_5 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 312.0
SHD1_k127_1853155_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000003278 250.0
SHD1_k127_1853155_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000009751 73.0
SHD1_k127_1853155_8 - - - - 0.000000001352 61.0
SHD1_k127_1853155_9 - - - - 0.0005921 45.0
SHD1_k127_1903434_0 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 436.0
SHD1_k127_1903434_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 401.0
SHD1_k127_1903434_2 Short-chain dehydrogenase reductase sdr K18335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
SHD1_k127_1903434_3 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000003179 231.0
SHD1_k127_1903434_4 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 0.00000000000000000000000000000000000000000000000000000000000001546 218.0
SHD1_k127_1903434_5 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000003057 198.0
SHD1_k127_1959708_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 531.0
SHD1_k127_1959708_1 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 442.0
SHD1_k127_1959708_2 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 405.0
SHD1_k127_1959708_3 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000001359 193.0
SHD1_k127_1983944_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 1.16e-244 761.0
SHD1_k127_1983944_1 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 308.0
SHD1_k127_1983944_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000001469 193.0
SHD1_k127_2007901_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 490.0
SHD1_k127_2007901_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 424.0
SHD1_k127_2007901_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 321.0
SHD1_k127_2007901_3 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
SHD1_k127_2007901_4 OmpA family K03286 - - 0.00000000000000000000000000000000000000000000000000000007481 203.0
SHD1_k127_2019516_0 carboxylase K01969 - 6.4.1.4 4.153e-279 866.0
SHD1_k127_2019516_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 1.319e-235 760.0
SHD1_k127_2019516_10 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004499 229.0
SHD1_k127_2019516_11 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000004281 222.0
SHD1_k127_2019516_12 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000000001026 149.0
SHD1_k127_2019516_13 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000753 143.0
SHD1_k127_2019516_14 PFAM Cytochrome C K17230 - - 0.0000000000000000000000003164 119.0
SHD1_k127_2019516_15 Protein of unknown function (DUF1289) K06938 - - 0.000000001545 66.0
SHD1_k127_2019516_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 586.0
SHD1_k127_2019516_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 462.0
SHD1_k127_2019516_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 451.0
SHD1_k127_2019516_5 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 400.0
SHD1_k127_2019516_6 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 313.0
SHD1_k127_2019516_7 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 302.0
SHD1_k127_2019516_8 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000001163 227.0
SHD1_k127_2019516_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000001639 227.0
SHD1_k127_205089_0 Amino acid permease - - - 5.982e-258 813.0
SHD1_k127_205089_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 443.0
SHD1_k127_205089_10 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000007321 98.0
SHD1_k127_205089_11 - - - - 0.0000000000000000000006421 104.0
SHD1_k127_205089_2 LysM domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 419.0
SHD1_k127_205089_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 411.0
SHD1_k127_205089_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 298.0
SHD1_k127_205089_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 273.0
SHD1_k127_205089_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000008332 226.0
SHD1_k127_205089_7 Thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000000000002473 182.0
SHD1_k127_205089_8 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000001175 159.0
SHD1_k127_205089_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001002 127.0
SHD1_k127_2058619_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 577.0
SHD1_k127_2058619_1 Creatinine amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
SHD1_k127_2058619_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000003711 247.0
SHD1_k127_2058619_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000006601 183.0
SHD1_k127_2058619_4 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000009381 155.0
SHD1_k127_2058619_5 ATP-grasp K01955 - 6.3.5.5 0.0000000000000000000000000000000000006106 154.0
SHD1_k127_2058619_6 Xylose isomerase - - - 0.000000000000000000000000005474 111.0
SHD1_k127_2058619_7 - - - - 0.0000000000000003512 84.0
SHD1_k127_2058619_8 YXWGXW repeat (2 copies) - - - 0.0000000000000113 79.0
SHD1_k127_206163_0 Glycosyl transferase family 21 K03669 - - 2.578e-320 1003.0
SHD1_k127_206163_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 2.512e-212 667.0
SHD1_k127_206163_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 491.0
SHD1_k127_206163_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 448.0
SHD1_k127_206163_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 417.0
SHD1_k127_206163_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 336.0
SHD1_k127_206163_6 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000002461 191.0
SHD1_k127_206163_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000001937 132.0
SHD1_k127_206223_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 580.0
SHD1_k127_206223_1 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 586.0
SHD1_k127_206223_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 544.0
SHD1_k127_206223_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 366.0
SHD1_k127_206223_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 318.0
SHD1_k127_2082934_0 ABC transporter transmembrane region K06147,K18893 - - 4.959e-308 957.0
SHD1_k127_2082934_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 593.0
SHD1_k127_2082934_10 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000001322 207.0
SHD1_k127_2082934_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000005019 202.0
SHD1_k127_2082934_12 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000005562 202.0
SHD1_k127_2082934_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000065 169.0
SHD1_k127_2082934_14 - - - - 0.000000000000000000000005982 111.0
SHD1_k127_2082934_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000007275 98.0
SHD1_k127_2082934_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 558.0
SHD1_k127_2082934_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 503.0
SHD1_k127_2082934_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 368.0
SHD1_k127_2082934_5 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 348.0
SHD1_k127_2082934_6 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 377.0
SHD1_k127_2082934_7 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004359 272.0
SHD1_k127_2082934_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000008231 221.0
SHD1_k127_2082934_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000002383 211.0
SHD1_k127_2089081_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.806e-300 930.0
SHD1_k127_2089081_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.176e-260 816.0
SHD1_k127_2089081_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 578.0
SHD1_k127_2089081_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000009122 158.0
SHD1_k127_2089081_4 - - - - 0.000000001333 71.0
SHD1_k127_2091039_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.201e-225 709.0
SHD1_k127_2091039_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 5.811e-225 705.0
SHD1_k127_2091039_10 Sporulation related domain K03749 - - 0.00000000000000000004278 99.0
SHD1_k127_2091039_11 pilus assembly protein FimV K08086 - - 0.00000000000000000005456 101.0
SHD1_k127_2091039_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 605.0
SHD1_k127_2091039_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 475.0
SHD1_k127_2091039_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 448.0
SHD1_k127_2091039_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 340.0
SHD1_k127_2091039_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 333.0
SHD1_k127_2091039_7 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000003663 241.0
SHD1_k127_2091039_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
SHD1_k127_2091039_9 Colicin V production K03558 - - 0.0000000000000000000000000003528 128.0
SHD1_k127_2097566_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 416.0
SHD1_k127_2097566_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000001994 181.0
SHD1_k127_2097566_2 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000009542 146.0
SHD1_k127_2097566_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.000000000000000000000000001182 126.0
SHD1_k127_2097566_4 - K06950 - - 0.000000002439 61.0
SHD1_k127_2097566_5 - - - - 0.000000006998 61.0
SHD1_k127_2118137_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.794e-256 803.0
SHD1_k127_2118137_1 MmgE/PrpD family - - - 1.289e-194 617.0
SHD1_k127_2118137_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 427.0
SHD1_k127_2118137_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 404.0
SHD1_k127_2118137_4 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 363.0
SHD1_k127_2118137_5 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000002065 234.0
SHD1_k127_2118137_6 Haem-degrading - - - 0.000000000000000000000000000000000000000007241 161.0
SHD1_k127_2136140_0 FAD linked oxidase - - - 1.572e-257 799.0
SHD1_k127_2136140_1 Protein of unknown function, DUF255 K06888 - - 4.364e-214 684.0
SHD1_k127_2136140_2 - - - - 0.0000000000000000000000000000008396 139.0
SHD1_k127_2156105_0 CoA-binding domain protein - - - 0.0 1183.0
SHD1_k127_2156105_1 Major Facilitator Superfamily K08177 - - 7.82e-196 619.0
SHD1_k127_2156105_2 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 570.0
SHD1_k127_2156105_3 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 479.0
SHD1_k127_2156105_4 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 306.0
SHD1_k127_2168957_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 2.337e-283 881.0
SHD1_k127_2168957_1 O-methyltransferase activity - - - 3.061e-206 662.0
SHD1_k127_2168957_11 Belongs to the 'phage' integrase family - - - 0.000171 44.0
SHD1_k127_2168957_2 Belongs to the DapA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 383.0
SHD1_k127_2168957_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 370.0
SHD1_k127_2168957_4 Belongs to the LDH2 MDH2 oxidoreductase family K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 336.0
SHD1_k127_2168957_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
SHD1_k127_2168957_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003559 269.0
SHD1_k127_2168957_7 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000001047 259.0
SHD1_k127_2168957_8 Cold-shock DNA-binding domain protein K03704 - - 0.0000000000000000000000000000000009015 131.0
SHD1_k127_2168957_9 O-Antigen ligase - - - 0.000000000000000000000000000002103 136.0
SHD1_k127_2225103_0 Belongs to the GcvT family K00302 - 1.5.3.1 5.524e-317 1000.0
SHD1_k127_2225103_1 FAD dependent oxidoreductase - - - 2.41e-213 670.0
SHD1_k127_2225103_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 468.0
SHD1_k127_2225103_3 FAD dependent oxidoreductase K22084 - 1.5.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002374 267.0
SHD1_k127_2225103_4 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001079 250.0
SHD1_k127_2225103_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000001753 218.0
SHD1_k127_2225103_6 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.000000000000000000000000000001369 123.0
SHD1_k127_2225103_7 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 - - 0.000000000000000000005543 93.0
SHD1_k127_2225103_8 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.000000000000000000007656 102.0
SHD1_k127_2240378_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 608.0
SHD1_k127_2240378_1 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 485.0
SHD1_k127_2240378_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000292 117.0
SHD1_k127_2240378_11 response regulator K02483,K07666,K07774 - - 0.00000000000000000007514 92.0
SHD1_k127_2240378_12 - - - - 0.00002496 49.0
SHD1_k127_2240378_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 359.0
SHD1_k127_2240378_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
SHD1_k127_2240378_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001145 262.0
SHD1_k127_2240378_5 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003925 259.0
SHD1_k127_2240378_6 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000005381 253.0
SHD1_k127_2240378_7 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006129 236.0
SHD1_k127_2240378_8 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000894 222.0
SHD1_k127_2240378_9 TonB dependent receptor K16092 - - 0.000000000000000000000000000008365 121.0
SHD1_k127_2283650_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001421 309.0
SHD1_k127_2283650_1 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000007183 158.0
SHD1_k127_2283650_2 PFAM PRC-barrel domain protein - - - 0.00000000000002255 79.0
SHD1_k127_2283650_3 SMART Transport-associated and nodulation - - - 0.00000000000002654 79.0
SHD1_k127_2283650_4 Belongs to the UPF0337 (CsbD) family - - - 0.000002231 52.0
SHD1_k127_2305390_0 Transcriptional regulator K03603,K05799 - - 5.122e-283 897.0
SHD1_k127_2305390_1 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 3.944e-204 656.0
SHD1_k127_2305390_2 PhoH-like phosphate starvation-inducible protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 467.0
SHD1_k127_2305390_3 PFAM CBS domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 382.0
SHD1_k127_2305390_4 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 307.0
SHD1_k127_2305390_5 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000003034 181.0
SHD1_k127_2305390_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000001724 162.0
SHD1_k127_2305390_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000009832 73.0
SHD1_k127_2337373_0 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.0 1076.0
SHD1_k127_2337373_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.816e-292 904.0
SHD1_k127_2337373_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.865e-269 848.0
SHD1_k127_234797_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 4.919e-248 782.0
SHD1_k127_234797_1 Rod shape-determining protein MreB K03569 - - 1.035e-194 611.0
SHD1_k127_234797_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 443.0
SHD1_k127_234797_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006145 270.0
SHD1_k127_234797_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004138 263.0
SHD1_k127_234797_5 shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000005321 163.0
SHD1_k127_2408584_0 protein synthesis factor, GTP-binding K06207 - - 1.366e-308 955.0
SHD1_k127_2408584_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 5.501e-243 765.0
SHD1_k127_2408584_2 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 571.0
SHD1_k127_2408584_3 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 522.0
SHD1_k127_2408584_4 DNA recombination protein RmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 443.0
SHD1_k127_2408584_5 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 372.0
SHD1_k127_2408584_6 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 289.0
SHD1_k127_2408584_7 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003814 264.0
SHD1_k127_2408584_8 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000001179 137.0
SHD1_k127_2408584_9 - - - - 0.000000000000000000000003961 107.0
SHD1_k127_2431806_0 Transport of potassium into the cell K03549 - - 2.232e-254 799.0
SHD1_k127_2431806_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 467.0
SHD1_k127_2431806_2 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004796 285.0
SHD1_k127_2431806_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 249.0
SHD1_k127_2431806_4 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000004416 225.0
SHD1_k127_2431806_5 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000005845 156.0
SHD1_k127_2431806_6 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000001264 149.0
SHD1_k127_2431806_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000002829 117.0
SHD1_k127_2433879_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 568.0
SHD1_k127_2433879_1 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 567.0
SHD1_k127_2433879_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008111 275.0
SHD1_k127_2433879_3 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
SHD1_k127_2433879_4 ARD/ARD' family K00450 - 1.13.11.4 0.000000000000000000000000000000000000002372 151.0
SHD1_k127_2433879_5 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000004624 134.0
SHD1_k127_2433879_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000009092 123.0
SHD1_k127_2433879_7 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000007973 53.0
SHD1_k127_2446908_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 399.0
SHD1_k127_2446908_1 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.000000000000000000000000000000000000000000000005626 181.0
SHD1_k127_2448515_0 Adenylate cyclase - - - 5.163e-224 715.0
SHD1_k127_2448515_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 527.0
SHD1_k127_244940_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1240.0
SHD1_k127_244940_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1055.0
SHD1_k127_244940_2 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 5.444e-206 653.0
SHD1_k127_244940_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01758,K01760 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.4.1.1,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 565.0
SHD1_k127_244940_4 COG0436 Aspartate tyrosine aromatic aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 471.0
SHD1_k127_244940_5 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 366.0
SHD1_k127_244940_6 Dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 308.0
SHD1_k127_244940_7 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000002397 182.0
SHD1_k127_244940_8 AAA domain (dynein-related subfamily) - - - 0.000000000002947 69.0
SHD1_k127_2461436_0 4Fe-4S dicluster domain - - - 1.84e-227 724.0
SHD1_k127_2461436_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 611.0
SHD1_k127_2461436_10 Protein of unknown function (DUF3563) - - - 0.0006689 46.0
SHD1_k127_2461436_2 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 497.0
SHD1_k127_2461436_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 494.0
SHD1_k127_2461436_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 414.0
SHD1_k127_2461436_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000002094 260.0
SHD1_k127_2461436_6 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000006908 217.0
SHD1_k127_2461436_7 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000004621 135.0
SHD1_k127_2461436_8 Protein of unknown function (DUF3306) - - - 0.000000000000000000000001287 114.0
SHD1_k127_2461436_9 Nitrate reductase delta subunit - - - 0.000000000000000003099 89.0
SHD1_k127_2464584_0 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 4.048e-203 656.0
SHD1_k127_2464584_1 Autotransporter beta-domain K12686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 328.0
SHD1_k127_2464584_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007507 277.0
SHD1_k127_2464584_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000003531 235.0
SHD1_k127_2464584_4 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000006331 185.0
SHD1_k127_2464584_5 cell division protein - - - 0.00000000000000000000000000002591 124.0
SHD1_k127_2560386_0 Sugar (and other) transporter - - - 4.06e-259 807.0
SHD1_k127_2560386_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.729e-207 659.0
SHD1_k127_2560386_2 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 599.0
SHD1_k127_2560386_3 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 534.0
SHD1_k127_2560386_4 Methyltransferase K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 368.0
SHD1_k127_2560386_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 331.0
SHD1_k127_2560386_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
SHD1_k127_2560386_7 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000005936 202.0
SHD1_k127_2560386_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000415 178.0
SHD1_k127_2560386_9 Transglycosylase associated protein - - - 0.00000000000000209 78.0
SHD1_k127_2652427_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1141.0
SHD1_k127_2652427_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 6.603e-239 742.0
SHD1_k127_2652427_10 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000001937 151.0
SHD1_k127_2652427_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000361 143.0
SHD1_k127_2652427_12 cytochrome - - - 0.0000000000001424 76.0
SHD1_k127_2652427_13 Tfp pilus assembly protein FimV - - - 0.000001546 60.0
SHD1_k127_2652427_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 520.0
SHD1_k127_2652427_3 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 501.0
SHD1_k127_2652427_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 489.0
SHD1_k127_2652427_5 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 347.0
SHD1_k127_2652427_6 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003527 275.0
SHD1_k127_2652427_7 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002644 263.0
SHD1_k127_2652427_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 253.0
SHD1_k127_2652427_9 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.0000000000000000000000000000000000000000005774 163.0
SHD1_k127_2652635_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 488.0
SHD1_k127_2652635_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 467.0
SHD1_k127_2652635_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 368.0
SHD1_k127_2652635_3 psiF repeat - - - 0.000000000000000006789 87.0
SHD1_k127_2652635_4 X-Pro dipeptidyl-peptidase (S15 family) - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000496 55.0
SHD1_k127_2652635_5 PFAM PsiF repeat protein - - - 0.0001123 48.0
SHD1_k127_2663879_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 609.0
SHD1_k127_2663879_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 471.0
SHD1_k127_26666_0 Binding-protein-dependent transport system inner membrane component K02011 - - 8.051e-250 782.0
SHD1_k127_26666_1 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 561.0
SHD1_k127_26666_2 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 528.0
SHD1_k127_26666_3 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 471.0
SHD1_k127_26666_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 404.0
SHD1_k127_26666_5 ABC transporter K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 396.0
SHD1_k127_26666_6 SAF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 365.0
SHD1_k127_2678527_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 7.882e-261 809.0
SHD1_k127_2678527_1 cation transport ATPase K01533 - 3.6.3.4 2.674e-221 714.0
SHD1_k127_2678527_10 - - - - 0.000000000000000000000000005512 124.0
SHD1_k127_2678527_11 Cytochrome oxidase maturation protein - - - 0.000000000000007712 75.0
SHD1_k127_2678527_12 COG4736 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.00003554 49.0
SHD1_k127_2678527_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 607.0
SHD1_k127_2678527_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 440.0
SHD1_k127_2678527_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 389.0
SHD1_k127_2678527_5 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 338.0
SHD1_k127_2678527_6 iron-sulfur 4fe-4s ferredoxin transmembrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009478 246.0
SHD1_k127_2678527_7 Cyclic nucleotide-binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000001556 213.0
SHD1_k127_2678527_8 - - - - 0.0000000000000000000000000000000000000000000001856 177.0
SHD1_k127_2678527_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000009127 164.0
SHD1_k127_2680552_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.108e-279 870.0
SHD1_k127_2680552_1 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 440.0
SHD1_k127_2680552_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 357.0
SHD1_k127_2680552_3 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004966 270.0
SHD1_k127_2680552_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000002991 123.0
SHD1_k127_2680552_5 Putative regulatory protein - - - 0.0000000000000000000000000008992 117.0
SHD1_k127_2702138_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.776e-250 786.0
SHD1_k127_2702138_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 417.0
SHD1_k127_2702138_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 329.0
SHD1_k127_2702138_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 269.0
SHD1_k127_2702138_4 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000009013 147.0
SHD1_k127_2703218_0 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
SHD1_k127_2703218_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 401.0
SHD1_k127_2703218_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 313.0
SHD1_k127_2703218_3 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003033 279.0
SHD1_k127_2703218_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000003992 217.0
SHD1_k127_2723542_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.584e-301 938.0
SHD1_k127_2723542_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.068e-234 734.0
SHD1_k127_2723542_2 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 415.0
SHD1_k127_2723542_3 Succinate dehydrogenase, hydrophobic K00242 - - 0.0000000000000000000000000000000000003388 147.0
SHD1_k127_2723542_4 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000003016 86.0
SHD1_k127_2723542_5 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000001745 75.0
SHD1_k127_2742544_0 PFAM Glycosyl transferase, family 20 K00697 - 2.4.1.15,2.4.1.347 3.5e-323 1004.0
SHD1_k127_2742544_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.074e-242 775.0
SHD1_k127_2742544_2 Glycosyl hydrolases family 15 - - - 2.275e-239 754.0
SHD1_k127_2742544_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 574.0
SHD1_k127_2742544_4 transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 436.0
SHD1_k127_2742544_5 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 296.0
SHD1_k127_2742544_6 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000008284 226.0
SHD1_k127_2742544_7 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000003294 214.0
SHD1_k127_275147_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 3.103e-293 919.0
SHD1_k127_275147_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 414.0
SHD1_k127_275147_2 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 378.0
SHD1_k127_275147_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009722 259.0
SHD1_k127_275147_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000006476 192.0
SHD1_k127_275147_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000001737 184.0
SHD1_k127_275147_6 - - - - 0.00000000000000533 76.0
SHD1_k127_2790023_0 PFAM Glycoside hydrolase 15-related - - - 2.432e-241 784.0
SHD1_k127_2790023_1 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 591.0
SHD1_k127_2790023_2 ABC-type sugar transport systems, permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 459.0
SHD1_k127_2790023_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 381.0
SHD1_k127_2790023_4 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 385.0
SHD1_k127_2807568_0 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 443.0
SHD1_k127_2807568_1 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 422.0
SHD1_k127_2807568_2 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000004008 205.0
SHD1_k127_2807568_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000003488 199.0
SHD1_k127_2807568_4 Esterase, PHB depolymerase family - - - 0.00000000000000000000000000000000000000000000000000137 196.0
SHD1_k127_2807568_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000003188 169.0
SHD1_k127_2807568_6 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000002498 162.0
SHD1_k127_2807568_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000003218 150.0
SHD1_k127_2900698_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 8.466e-294 932.0
SHD1_k127_2900698_1 Thi4 family - - - 2.87e-224 713.0
SHD1_k127_2900698_10 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 334.0
SHD1_k127_2900698_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 301.0
SHD1_k127_2900698_12 Pfam:DUF989 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 293.0
SHD1_k127_2900698_13 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 291.0
SHD1_k127_2900698_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
SHD1_k127_2900698_15 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005776 282.0
SHD1_k127_2900698_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
SHD1_k127_2900698_17 KR domain K00059,K21883 - 1.1.1.100,1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000004228 259.0
SHD1_k127_2900698_18 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000414 249.0
SHD1_k127_2900698_19 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000007068 235.0
SHD1_k127_2900698_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.795e-206 650.0
SHD1_k127_2900698_20 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000001358 190.0
SHD1_k127_2900698_21 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000001931 191.0
SHD1_k127_2900698_22 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003658 186.0
SHD1_k127_2900698_23 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000005241 182.0
SHD1_k127_2900698_24 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000007545 173.0
SHD1_k127_2900698_25 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000128 156.0
SHD1_k127_2900698_26 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.0000000000000000000000000000000000000001968 165.0
SHD1_k127_2900698_27 Cell division and transport-associated protein TolA K03646 - - 0.0000000000000000000000000000000004203 146.0
SHD1_k127_2900698_28 short-chain dehydrogenase K16216 - 1.1.1.320 0.0000000000000000000000000000000004915 141.0
SHD1_k127_2900698_29 - - - - 0.00000000000000000000000000002685 135.0
SHD1_k127_2900698_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 563.0
SHD1_k127_2900698_30 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000354 119.0
SHD1_k127_2900698_31 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000009572 71.0
SHD1_k127_2900698_32 Peptidase S16, lon domain protein K07157 - - 0.000000008282 57.0
SHD1_k127_2900698_4 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 520.0
SHD1_k127_2900698_5 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 474.0
SHD1_k127_2900698_6 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 471.0
SHD1_k127_2900698_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 370.0
SHD1_k127_2900698_8 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 370.0
SHD1_k127_2900698_9 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 329.0
SHD1_k127_2911287_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.035e-320 994.0
SHD1_k127_2911287_1 Peptidase family M13 K07386 - - 2.968e-277 874.0
SHD1_k127_2911287_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 617.0
SHD1_k127_2911287_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 495.0
SHD1_k127_2911287_4 PFAM O-methyltransferase, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002678 260.0
SHD1_k127_2911287_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000849 224.0
SHD1_k127_2911287_6 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000003245 210.0
SHD1_k127_2921004_0 ABC-type dipeptide transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 559.0
SHD1_k127_2921004_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 350.0
SHD1_k127_2921004_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 318.0
SHD1_k127_2921004_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 321.0
SHD1_k127_2921004_4 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
SHD1_k127_2935240_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.634e-272 848.0
SHD1_k127_2935240_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 426.0
SHD1_k127_2935240_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 292.0
SHD1_k127_2935240_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000006212 247.0
SHD1_k127_2935240_4 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.000000000000000000000000000000000000000000000000000001823 198.0
SHD1_k127_2935240_5 ATP-grasp K01955 - 6.3.5.5 0.00000000000000000000000000000000000006108 158.0
SHD1_k127_2935240_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000002091 143.0
SHD1_k127_2935240_7 - - - - 0.00000000000000000003444 104.0
SHD1_k127_2981838_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 556.0
SHD1_k127_2981838_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 500.0
SHD1_k127_2981838_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000003279 70.0
SHD1_k127_2981838_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 402.0
SHD1_k127_2981838_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
SHD1_k127_2981838_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000007474 241.0
SHD1_k127_2981838_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000001758 228.0
SHD1_k127_2981838_6 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000431 198.0
SHD1_k127_2981838_7 ATP-grasp - - - 0.0000000000000000000000000000000009019 144.0
SHD1_k127_2981838_8 Outer membrane lipoprotein LolB - - - 0.000000000000000000000000005486 121.0
SHD1_k127_2981838_9 PFAM conserved - - - 0.000000000000000000005414 96.0
SHD1_k127_2986331_0 OPT oligopeptide transporter protein - - - 9.579e-261 815.0
SHD1_k127_2986331_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 547.0
SHD1_k127_2986331_10 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
SHD1_k127_2986331_11 PFAM ATPase, BadF BadG BcrA BcrD type K18676 - 2.7.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002133 281.0
SHD1_k127_2986331_12 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000112 213.0
SHD1_k127_2986331_13 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.0000000000000000000000000000000002412 150.0
SHD1_k127_2986331_15 cation diffusion facilitator family transporter - - - 0.000000000006945 70.0
SHD1_k127_2986331_16 response to abiotic stimulus K06867 - - 0.000000287 62.0
SHD1_k127_2986331_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 502.0
SHD1_k127_2986331_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 496.0
SHD1_k127_2986331_4 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 444.0
SHD1_k127_2986331_5 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 417.0
SHD1_k127_2986331_6 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 394.0
SHD1_k127_2986331_7 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 349.0
SHD1_k127_2986331_8 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 338.0
SHD1_k127_2986331_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 328.0
SHD1_k127_3017890_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 4.821e-311 970.0
SHD1_k127_3017890_1 Protein of unknown function - - - 7.303e-271 880.0
SHD1_k127_3017890_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.937e-269 866.0
SHD1_k127_3017890_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 518.0
SHD1_k127_3017890_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 496.0
SHD1_k127_3017890_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 359.0
SHD1_k127_3017890_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004509 278.0
SHD1_k127_3017890_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000002162 181.0
SHD1_k127_3017890_8 Small MutS-related domain - - - 0.000000000000000000000000000000000000000888 156.0
SHD1_k127_3017890_9 protein conserved in bacteria - - - 0.0000000000000000000839 96.0
SHD1_k127_3045278_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 8.511e-202 634.0
SHD1_k127_3045278_1 Deoxyhypusine synthase K00809 - 2.5.1.46 9.722e-199 631.0
SHD1_k127_3045278_2 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000008848 258.0
SHD1_k127_3055777_0 ferredoxin-NADP+ reductase activity K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 616.0
SHD1_k127_3055777_1 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 540.0
SHD1_k127_3055777_2 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K10674 - 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 443.0
SHD1_k127_3055777_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 429.0
SHD1_k127_3055777_4 Beta/gamma crystallins - - - 0.000000000000000000000000000000000000000001159 165.0
SHD1_k127_3055777_5 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.00000000000000000000000000000000000000007741 152.0
SHD1_k127_3055777_6 SAF - - - 0.000000000000000000000000000005215 124.0
SHD1_k127_3055777_7 - - - - 0.000000000000003558 78.0
SHD1_k127_3055777_8 transferase activity, transferring glycosyl groups - - - 0.00000000001584 69.0
SHD1_k127_3098203_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 2.89e-306 965.0
SHD1_k127_3098203_1 GGDEF domain containing protein - - - 6.294e-226 727.0
SHD1_k127_3098203_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 584.0
SHD1_k127_3098203_3 PFAM extracellular solute-binding protein family 1 K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 514.0
SHD1_k127_3098203_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 443.0
SHD1_k127_3098203_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 442.0
SHD1_k127_3098203_6 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002881 279.0
SHD1_k127_3098203_7 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009411 240.0
SHD1_k127_3098203_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000002051 153.0
SHD1_k127_3110141_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 559.0
SHD1_k127_3110141_1 Amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 530.0
SHD1_k127_3110141_2 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 475.0
SHD1_k127_3110141_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 447.0
SHD1_k127_3110141_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
SHD1_k127_3127003_0 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 0.0 1003.0
SHD1_k127_3127003_1 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 328.0
SHD1_k127_3127003_2 Phosphate acetyl/butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000241 282.0
SHD1_k127_3127003_3 Sulfate permease family K03321 - - 0.00000000000000000000000000001835 126.0
SHD1_k127_3127003_4 Sulfate permease family K03321 - - 0.000000000005431 79.0
SHD1_k127_3145195_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 9.354e-255 796.0
SHD1_k127_3145195_1 Binding-protein-dependent transport system inner membrane component K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 492.0
SHD1_k127_3145195_2 N-terminal TM domain of oligopeptide transport permease C K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 413.0
SHD1_k127_3145195_3 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 314.0
SHD1_k127_3145195_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K12371 - - 0.00000000000000000000000000000000000000000000005436 172.0
SHD1_k127_3148434_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 482.0
SHD1_k127_3148434_1 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 426.0
SHD1_k127_3148434_2 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 362.0
SHD1_k127_3148434_3 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001702 291.0
SHD1_k127_3148434_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000001159 224.0
SHD1_k127_3148434_5 ferredoxin - - - 0.0000000000000000000000000000000000001539 141.0
SHD1_k127_3148434_6 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000001503 126.0
SHD1_k127_3148434_7 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000208 111.0
SHD1_k127_3148434_8 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000001139 93.0
SHD1_k127_3169797_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 518.0
SHD1_k127_3169797_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 512.0
SHD1_k127_3169797_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 426.0
SHD1_k127_3169797_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 290.0
SHD1_k127_3169797_4 Protein of unknown function (DUF1282) - - - 0.00000000000000000000000000000000002161 147.0
SHD1_k127_3169797_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000001934 124.0
SHD1_k127_322275_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.323e-208 659.0
SHD1_k127_322275_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 580.0
SHD1_k127_322275_10 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000004177 147.0
SHD1_k127_322275_11 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000004668 140.0
SHD1_k127_322275_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000003984 128.0
SHD1_k127_322275_13 Phosphoribosyl transferase domain - - - 0.0000000000000001727 79.0
SHD1_k127_322275_14 Domain of unknown function (DUF4864) - - - 0.0000000000000009328 86.0
SHD1_k127_322275_15 Peptidase family M23 - - - 0.0000001742 59.0
SHD1_k127_322275_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 431.0
SHD1_k127_322275_3 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 422.0
SHD1_k127_322275_4 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 324.0
SHD1_k127_322275_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
SHD1_k127_322275_6 PFAM regulatory protein TetR K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
SHD1_k127_322275_7 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
SHD1_k127_322275_8 Glycosyltransferase Family 4 K02844 - - 0.00000000000000000000000000000000000000000000000000000005003 201.0
SHD1_k127_322275_9 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000001506 181.0
SHD1_k127_322767_0 Radical SAM K01012 - 2.8.1.6 5.688e-212 664.0
SHD1_k127_322767_1 PFAM Cysteine-rich - - - 3.638e-203 650.0
SHD1_k127_322767_10 NADP oxidoreductase coenzyme F420-dependent K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000005838 213.0
SHD1_k127_322767_11 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000004427 203.0
SHD1_k127_322767_12 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000002415 121.0
SHD1_k127_322767_13 - - - - 0.0000000000000000000000002169 108.0
SHD1_k127_322767_2 Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 509.0
SHD1_k127_322767_3 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 419.0
SHD1_k127_322767_4 Including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 415.0
SHD1_k127_322767_5 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 332.0
SHD1_k127_322767_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 308.0
SHD1_k127_322767_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002022 241.0
SHD1_k127_322767_8 GMP synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005015 231.0
SHD1_k127_322767_9 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000225 202.0
SHD1_k127_3274434_0 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 476.0
SHD1_k127_3274434_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 324.0
SHD1_k127_3274434_2 UPF0391 membrane protein - - - 0.0000000000000001301 80.0
SHD1_k127_3274434_3 CsbD-like - - - 0.000000000000006837 76.0
SHD1_k127_3274434_4 Sulfotransferase family - - - 0.0000009218 61.0
SHD1_k127_3274434_5 PFAM Entericidin - - - 0.0001221 50.0
SHD1_k127_3293218_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 391.0
SHD1_k127_3293218_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 317.0
SHD1_k127_3293218_2 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004741 256.0
SHD1_k127_3293218_3 - - - - 0.0000000000000000000000000000000000000000000002783 172.0
SHD1_k127_3293218_4 - - - - 0.000000000000000000000000000000002417 135.0
SHD1_k127_3293218_5 Transcriptional regulator - - - 0.0000000000000000000000000000005129 131.0
SHD1_k127_3293218_6 - - - - 0.00000001646 58.0
SHD1_k127_3305297_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 337.0
SHD1_k127_3305297_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000004472 155.0
SHD1_k127_3305297_2 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000002865 70.0
SHD1_k127_3306865_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 6.275e-210 661.0
SHD1_k127_3306865_1 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 451.0
SHD1_k127_3306865_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000008467 161.0
SHD1_k127_3306865_11 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.00000000000000000000000000000000000004114 159.0
SHD1_k127_3306865_12 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000003157 148.0
SHD1_k127_3306865_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000187 137.0
SHD1_k127_3306865_14 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000002093 132.0
SHD1_k127_3306865_15 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000001677 77.0
SHD1_k127_3306865_16 - - - - 0.00000000009065 74.0
SHD1_k127_3306865_17 Tetratricopeptide repeat - - - 0.0000009461 61.0
SHD1_k127_3306865_2 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 451.0
SHD1_k127_3306865_3 Lecithin:cholesterol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 369.0
SHD1_k127_3306865_4 zinc protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 353.0
SHD1_k127_3306865_5 glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 282.0
SHD1_k127_3306865_6 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005366 256.0
SHD1_k127_3306865_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000005003 201.0
SHD1_k127_3306865_8 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000007623 193.0
SHD1_k127_3306865_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000007513 180.0
SHD1_k127_3356094_0 ABC transport system ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 389.0
SHD1_k127_3356094_1 ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 376.0
SHD1_k127_3356094_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 358.0
SHD1_k127_3356094_3 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000005898 229.0
SHD1_k127_3356094_4 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000008709 229.0
SHD1_k127_3356094_5 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000002989 206.0
SHD1_k127_3356094_6 response to antibiotic K07122 - - 0.0002157 50.0
SHD1_k127_335623_0 ABC transporter substrate-binding protein K02035,K13889 - - 1.082e-195 624.0
SHD1_k127_335623_1 sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 518.0
SHD1_k127_335623_2 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 501.0
SHD1_k127_335623_3 Putative sugar-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 439.0
SHD1_k127_335623_4 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 344.0
SHD1_k127_335623_5 Carbohydrate transport and metabolism K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000003952 252.0
SHD1_k127_335623_6 SAF - - - 0.00000000000000000000000000000000000000000002276 165.0
SHD1_k127_335623_7 - - - - 0.000000000000003135 78.0
SHD1_k127_335623_8 - - - - 0.0000004604 56.0
SHD1_k127_3357858_0 Acyl-CoA dehydrogenase N terminal K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 487.0
SHD1_k127_3357858_1 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 430.0
SHD1_k127_3357858_2 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 388.0
SHD1_k127_3428161_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1224.0
SHD1_k127_3428161_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 389.0
SHD1_k127_3428161_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000006442 171.0
SHD1_k127_3428161_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000001256 111.0
SHD1_k127_3486734_0 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 563.0
SHD1_k127_3486734_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 464.0
SHD1_k127_3486734_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000135 143.0
SHD1_k127_3486734_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000007953 98.0
SHD1_k127_3486734_12 Protein of unknown function (DUF3108) - - - 0.000000000000000000005343 105.0
SHD1_k127_3486734_2 ribosomal RNA small subunit methyltransferase B K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 460.0
SHD1_k127_3486734_3 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 358.0
SHD1_k127_3486734_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 331.0
SHD1_k127_3486734_5 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 315.0
SHD1_k127_3486734_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000263 264.0
SHD1_k127_3486734_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
SHD1_k127_3486734_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000005963 180.0
SHD1_k127_3486734_9 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000001502 162.0
SHD1_k127_3503147_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.008e-245 765.0
SHD1_k127_3503147_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 558.0
SHD1_k127_3503147_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 510.0
SHD1_k127_3503147_3 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 422.0
SHD1_k127_3503147_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 356.0
SHD1_k127_3503147_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 344.0
SHD1_k127_3503147_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 289.0
SHD1_k127_3503147_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000000000000000002072 176.0
SHD1_k127_3503147_8 Entericidin EcnA/B family - - - 0.00002068 48.0
SHD1_k127_3528808_0 Acyl-CoA dehydrogenase, N-terminal domain K00252 - 1.3.8.6 1.532e-204 647.0
SHD1_k127_3528808_1 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 299.0
SHD1_k127_3528808_2 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 289.0
SHD1_k127_3528808_3 PFAM fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001054 278.0
SHD1_k127_3528808_4 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000000000001093 137.0
SHD1_k127_3528808_5 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000716 126.0
SHD1_k127_3528808_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000005328 108.0
SHD1_k127_3528808_7 Tfp pilus assembly protein FimT K08084 - - 0.000000000000005302 83.0
SHD1_k127_3528808_8 type IV pilus modification protein PilV K02671 - - 0.00000000000006827 82.0
SHD1_k127_354624_0 type II secretion system protein E K02454,K02504,K02652,K12276 - - 2.381e-251 787.0
SHD1_k127_354624_1 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 516.0
SHD1_k127_354624_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 402.0
SHD1_k127_354624_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 344.0
SHD1_k127_354624_4 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 337.0
SHD1_k127_354624_5 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 306.0
SHD1_k127_354624_6 Dephospho-CoA kinase K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000757 184.0
SHD1_k127_356862_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 8.051e-254 790.0
SHD1_k127_356862_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 469.0
SHD1_k127_356862_10 Membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000005509 65.0
SHD1_k127_356862_2 MBOAT, membrane-bound O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 377.0
SHD1_k127_356862_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 354.0
SHD1_k127_356862_4 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 316.0
SHD1_k127_356862_5 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000009602 176.0
SHD1_k127_356862_6 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000002368 175.0
SHD1_k127_356862_7 - - - - 0.00000000000000000000000000000003725 140.0
SHD1_k127_356862_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000044 129.0
SHD1_k127_356862_9 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000008013 98.0
SHD1_k127_3569498_0 enoyl-CoA hydratase K15513 - 4.1.2.44 6.09e-264 824.0
SHD1_k127_3569498_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 9.811e-251 784.0
SHD1_k127_3569498_2 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 566.0
SHD1_k127_3569498_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 436.0
SHD1_k127_3569498_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 379.0
SHD1_k127_3569498_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 346.0
SHD1_k127_3569498_6 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 338.0
SHD1_k127_3569498_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 319.0
SHD1_k127_3569498_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000729 228.0
SHD1_k127_3569498_9 Domain of unknown function (DUF4863) - - - 0.00000000000000000000000000000000000000000000000000000000009741 207.0
SHD1_k127_3586744_0 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 551.0
SHD1_k127_3586744_1 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 408.0
SHD1_k127_3586744_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002598 259.0
SHD1_k127_3586744_3 PKHD-type hydroxylase K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001929 249.0
SHD1_k127_3586744_4 Protein of unknown function (DUF3313) - - - 0.00000000000000000002737 99.0
SHD1_k127_3586744_5 - - - - 0.000000000000002413 86.0
SHD1_k127_3591959_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 8.074e-304 956.0
SHD1_k127_3591959_1 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 396.0
SHD1_k127_3591959_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 289.0
SHD1_k127_3591959_3 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001059 205.0
SHD1_k127_3591959_4 - - - - 0.000000000000000000000000008263 123.0
SHD1_k127_3591959_5 Domain of unknown function (DUF4397) - - - 0.00000000000000000001561 105.0
SHD1_k127_3591959_6 Domain of unknown function (DUF4397) - - - 0.00000000000004562 85.0
SHD1_k127_3591959_7 TIGRFAM LPXTG-motif cell wall anchor domain - - - 0.000000000125 74.0
SHD1_k127_3621777_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1150.0
SHD1_k127_3621777_1 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 359.0
SHD1_k127_3621777_2 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 316.0
SHD1_k127_3621777_3 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 287.0
SHD1_k127_3621777_4 amine dehydrogenase activity - - - 0.000001154 59.0
SHD1_k127_3624132_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.696e-313 968.0
SHD1_k127_3624132_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.571e-276 858.0
SHD1_k127_3624132_10 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 337.0
SHD1_k127_3624132_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 319.0
SHD1_k127_3624132_12 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000008061 262.0
SHD1_k127_3624132_13 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000003718 234.0
SHD1_k127_3624132_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000006938 190.0
SHD1_k127_3624132_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000002111 175.0
SHD1_k127_3624132_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000006379 170.0
SHD1_k127_3624132_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000002035 143.0
SHD1_k127_3624132_18 ThiS family K03636 - - 0.00000000000000000001013 101.0
SHD1_k127_3624132_19 Periplasmic binding proteins and sugar binding domain of LacI family K02529,K05499 - - 0.0000000000000000001603 100.0
SHD1_k127_3624132_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.42e-265 820.0
SHD1_k127_3624132_20 ATP synthase I chain K02116 - - 0.000000000000007241 79.0
SHD1_k127_3624132_3 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 569.0
SHD1_k127_3624132_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 572.0
SHD1_k127_3624132_5 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 508.0
SHD1_k127_3624132_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 502.0
SHD1_k127_3624132_7 Psort location Cytoplasmic, score 7.50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 490.0
SHD1_k127_3624132_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 378.0
SHD1_k127_3624132_9 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 340.0
SHD1_k127_3684649_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1836.0
SHD1_k127_3684649_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 2.84e-207 653.0
SHD1_k127_3684649_2 response regulator K02481,K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 567.0
SHD1_k127_3684649_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 463.0
SHD1_k127_3684649_4 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 417.0
SHD1_k127_3684649_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 382.0
SHD1_k127_3684649_6 Histidine kinase K20975 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 316.0
SHD1_k127_3684649_7 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000002833 220.0
SHD1_k127_3684649_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000001536 178.0
SHD1_k127_3684649_9 Dihydrofolate reductase K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000001725 173.0
SHD1_k127_3688874_0 Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 9.358e-234 737.0
SHD1_k127_3688874_1 Aminotransferase K01845 - 5.4.3.8 4.573e-199 627.0
SHD1_k127_3688874_10 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005439 257.0
SHD1_k127_3688874_11 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000001605 199.0
SHD1_k127_3688874_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000003104 203.0
SHD1_k127_3688874_13 Glycosyltransferase like family - - - 0.00000000000000000000000000000000000000008238 165.0
SHD1_k127_3688874_14 signal sequence binding - - - 0.00000000000000000000000001583 119.0
SHD1_k127_3688874_15 Rubredoxin - - - 0.00000000000000000000001001 105.0
SHD1_k127_3688874_16 SURF1 family K14998 - - 0.0000000000000000002438 90.0
SHD1_k127_3688874_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 540.0
SHD1_k127_3688874_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
SHD1_k127_3688874_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 428.0
SHD1_k127_3688874_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 401.0
SHD1_k127_3688874_6 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 388.0
SHD1_k127_3688874_7 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 393.0
SHD1_k127_3688874_8 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 363.0
SHD1_k127_3688874_9 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000005633 258.0
SHD1_k127_3745552_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 550.0
SHD1_k127_3745552_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 456.0
SHD1_k127_3745552_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003564 259.0
SHD1_k127_3745552_3 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.00000000000000006354 93.0
SHD1_k127_3845397_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1548.0
SHD1_k127_3845397_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 533.0
SHD1_k127_3845397_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 485.0
SHD1_k127_3851964_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1e-222 700.0
SHD1_k127_3851964_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 490.0
SHD1_k127_3851964_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
SHD1_k127_3851964_3 PFAM permease YjgP YjgQ family protein K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004921 284.0
SHD1_k127_3851964_4 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000009785 143.0
SHD1_k127_3864202_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1281.0
SHD1_k127_3864202_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1089.0
SHD1_k127_3864202_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000001261 144.0
SHD1_k127_3864202_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000002243 140.0
SHD1_k127_3864202_2 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 612.0
SHD1_k127_3864202_3 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 559.0
SHD1_k127_3864202_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 394.0
SHD1_k127_3864202_5 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
SHD1_k127_3864202_6 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 323.0
SHD1_k127_3864202_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003829 214.0
SHD1_k127_3864202_8 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000001145 173.0
SHD1_k127_3864202_9 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000002136 145.0
SHD1_k127_3865093_0 transport system fused permease components - - - 4.007e-233 739.0
SHD1_k127_3865093_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 571.0
SHD1_k127_3865093_10 Protein of unknown function (DUF3301) - - - 0.0000000000000000000004617 100.0
SHD1_k127_3865093_11 - - - - 0.000000000000000001571 95.0
SHD1_k127_3865093_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 531.0
SHD1_k127_3865093_3 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 357.0
SHD1_k127_3865093_4 Dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001312 259.0
SHD1_k127_3865093_5 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000004841 215.0
SHD1_k127_3865093_6 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000002787 163.0
SHD1_k127_3865093_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000236 158.0
SHD1_k127_3865093_8 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000001136 119.0
SHD1_k127_3865093_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000007843 114.0
SHD1_k127_3871810_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 5.164e-303 939.0
SHD1_k127_3871810_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 392.0
SHD1_k127_3871810_2 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 360.0
SHD1_k127_3871810_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
SHD1_k127_3871810_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 327.0
SHD1_k127_3871810_5 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
SHD1_k127_3871810_6 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000002418 80.0
SHD1_k127_3919772_0 KR domain K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 351.0
SHD1_k127_3919772_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
SHD1_k127_3919772_10 Belongs to the peptidase S1B family - - - 0.000000000003347 79.0
SHD1_k127_3919772_11 Copper chaperone PCu(A)C K09796 - - 0.00006322 51.0
SHD1_k127_3919772_12 ribosome binding - - - 0.0002279 49.0
SHD1_k127_3919772_2 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 310.0
SHD1_k127_3919772_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000009516 226.0
SHD1_k127_3919772_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000001368 211.0
SHD1_k127_3919772_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000002863 166.0
SHD1_k127_3919772_6 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000002389 113.0
SHD1_k127_3919772_7 - K22311 - 2.3.1.265 0.000000000000000000000000346 110.0
SHD1_k127_3919772_8 protein import - - - 0.00000000000000000007487 104.0
SHD1_k127_3919772_9 Domain of unknown function (DUF4266) - - - 0.0000000000000000866 87.0
SHD1_k127_3933308_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 311.0
SHD1_k127_3933308_1 Transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001086 226.0
SHD1_k127_3933308_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000003807 135.0
SHD1_k127_3933308_3 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000002756 104.0
SHD1_k127_3933308_4 RDD family - - - 0.0000000000000001618 87.0
SHD1_k127_3933308_5 - - - - 0.0000535 54.0
SHD1_k127_394645_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1086.0
SHD1_k127_394645_1 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 3.173e-231 736.0
SHD1_k127_394645_10 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000002342 202.0
SHD1_k127_394645_11 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000001267 184.0
SHD1_k127_394645_12 Adenylate guanylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000002297 167.0
SHD1_k127_394645_13 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000001879 97.0
SHD1_k127_394645_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 500.0
SHD1_k127_394645_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 469.0
SHD1_k127_394645_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 445.0
SHD1_k127_394645_5 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 368.0
SHD1_k127_394645_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 357.0
SHD1_k127_394645_7 HlyD family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 316.0
SHD1_k127_394645_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 287.0
SHD1_k127_394645_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 247.0
SHD1_k127_3981704_0 Thiamine pyrophosphate enzyme, central domain - - - 5.387e-254 796.0
SHD1_k127_3981704_1 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 424.0
SHD1_k127_3981704_2 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 391.0
SHD1_k127_3981704_3 Belongs to the peptidase S8 family K08651,K14645 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000003974 269.0
SHD1_k127_3981704_4 peptidase - - - 0.00000000000000000000000000000000000000007465 169.0
SHD1_k127_3981704_5 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000355 116.0
SHD1_k127_4025725_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 3.313e-309 974.0
SHD1_k127_4025725_1 Belongs to the TPP enzyme family K03852 - 2.3.3.15 1.049e-279 870.0
SHD1_k127_4025725_2 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000005474 188.0
SHD1_k127_4025725_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000002358 177.0
SHD1_k127_4028914_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 593.0
SHD1_k127_4028914_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 568.0
SHD1_k127_4028914_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 486.0
SHD1_k127_4028914_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 455.0
SHD1_k127_4028914_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000004805 209.0
SHD1_k127_4028914_5 Psort location Cytoplasmic, score 8.96 K09117 - - 0.0000000000000000000000000000000000000000000000005983 178.0
SHD1_k127_4028914_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000003023 128.0
SHD1_k127_4028914_7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000001424 102.0
SHD1_k127_4069879_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 506.0
SHD1_k127_4069879_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 505.0
SHD1_k127_4069879_2 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 349.0
SHD1_k127_4069879_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000001773 145.0
SHD1_k127_4069879_4 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000001888 109.0
SHD1_k127_4069879_5 Pfam Response regulator receiver - - - 0.000004944 56.0
SHD1_k127_4093148_0 peptidase - - - 2.447e-260 816.0
SHD1_k127_4093148_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 431.0
SHD1_k127_4093148_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 432.0
SHD1_k127_4093148_3 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 386.0
SHD1_k127_4093148_4 Sulfate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 337.0
SHD1_k127_4093148_5 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003714 292.0
SHD1_k127_4093148_6 peptidase - - - 0.0000000000000051 78.0
SHD1_k127_4114435_0 general secretion pathway protein D K02453 - - 9.327e-200 649.0
SHD1_k127_4114435_1 Type II/IV secretion system protein K02454 - - 0.0000000000000000000000000000000000000000000005329 176.0
SHD1_k127_4128492_0 TRAP dicarboxylate transporter, DctM subunit K11690 - - 1.164e-221 694.0
SHD1_k127_4128492_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 576.0
SHD1_k127_4128492_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
SHD1_k127_4128492_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 531.0
SHD1_k127_4128492_4 Transporter K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 434.0
SHD1_k127_4128492_5 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 285.0
SHD1_k127_4128492_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000001206 246.0
SHD1_k127_4128492_7 type 4 pilus biogenesis protein K02656 - - 0.0000000000000000000000000000000000000000000000000000000000004334 223.0
SHD1_k127_4128492_8 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000000000000000002841 169.0
SHD1_k127_4128492_9 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000001206 98.0
SHD1_k127_4145807_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 501.0
SHD1_k127_4145807_1 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 419.0
SHD1_k127_4145807_2 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 390.0
SHD1_k127_4145807_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.00000000000000000000000000000004701 132.0
SHD1_k127_4145807_4 BON domain - - - 0.00000000000000000003702 98.0
SHD1_k127_4145807_5 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000008871 64.0
SHD1_k127_4162270_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.812e-194 615.0
SHD1_k127_4162270_1 Putative amidoligase enzyme (DUF2126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 607.0
SHD1_k127_4162270_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 537.0
SHD1_k127_4194889_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 601.0
SHD1_k127_4194889_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009783 402.0
SHD1_k127_4194889_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 324.0
SHD1_k127_4194889_3 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000002946 222.0
SHD1_k127_4194889_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000008443 84.0
SHD1_k127_4194889_5 alpha beta - - - 0.000000000000002599 87.0
SHD1_k127_4194889_6 Belongs to the P(II) protein family K04752 - - 0.00000000005208 62.0
SHD1_k127_4205905_0 Transmembrane secretion effector - - - 3.802e-255 800.0
SHD1_k127_4205905_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 6.576e-194 612.0
SHD1_k127_4205905_2 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 512.0
SHD1_k127_4205905_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 296.0
SHD1_k127_4205905_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000001207 191.0
SHD1_k127_4215025_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.519e-219 694.0
SHD1_k127_4215025_1 AmpG muropeptide MFS transporter K08218 K08218 - - 2.755e-194 614.0
SHD1_k127_4215025_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 566.0
SHD1_k127_4215025_3 PFAM ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 406.0
SHD1_k127_4215025_4 PFAM Methionine biosynthesis MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001043 261.0
SHD1_k127_4215025_5 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000005666 169.0
SHD1_k127_4215025_6 Phosphotransferase System K11189 - - 0.000000000000000000000000000000000758 132.0
SHD1_k127_4215025_7 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000006442 103.0
SHD1_k127_422832_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1567.0
SHD1_k127_422832_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.441e-203 649.0
SHD1_k127_422832_2 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 347.0
SHD1_k127_422832_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001487 273.0
SHD1_k127_422832_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001453 247.0
SHD1_k127_422832_5 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000000744 208.0
SHD1_k127_422832_6 Domain of unknown function (DUF3400) - - - 0.00000000000000000000000000001042 119.0
SHD1_k127_422832_7 Membrane fusogenic activity K09806 - - 0.00000000000000007118 94.0
SHD1_k127_4237883_0 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 473.0
SHD1_k127_4237883_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 383.0
SHD1_k127_4237883_2 Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 343.0
SHD1_k127_4237883_3 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 275.0
SHD1_k127_4237883_4 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 258.0
SHD1_k127_4237883_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000009459 137.0
SHD1_k127_4237883_6 - - - - 0.00000000000000000000006984 109.0
SHD1_k127_4244242_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 4.436e-195 620.0
SHD1_k127_4244242_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 559.0
SHD1_k127_4244242_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 416.0
SHD1_k127_4244242_3 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 333.0
SHD1_k127_4244242_4 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 312.0
SHD1_k127_4244242_5 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000006149 164.0
SHD1_k127_4244242_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000006527 167.0
SHD1_k127_4244242_7 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000002884 151.0
SHD1_k127_4244242_8 - - - - 0.0000000000000000000006605 99.0
SHD1_k127_4248483_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 611.0
SHD1_k127_4248483_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 437.0
SHD1_k127_4248483_10 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000005436 151.0
SHD1_k127_4248483_11 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000002266 101.0
SHD1_k127_4248483_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 344.0
SHD1_k127_4248483_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 326.0
SHD1_k127_4248483_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 322.0
SHD1_k127_4248483_5 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 286.0
SHD1_k127_4248483_6 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 251.0
SHD1_k127_4248483_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000006545 241.0
SHD1_k127_4248483_8 Glycosyltransferase like family 2 K20444 - - 0.0000000000000000000000000000000000000000002983 173.0
SHD1_k127_4248483_9 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000005237 159.0
SHD1_k127_4266799_0 TIGRFAM malate synthase A K01638 - 2.3.3.9 2.164e-255 797.0
SHD1_k127_4266799_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.13e-235 741.0
SHD1_k127_4266799_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 567.0
SHD1_k127_4266799_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 339.0
SHD1_k127_4266799_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 293.0
SHD1_k127_4266799_5 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009751 268.0
SHD1_k127_4266799_6 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
SHD1_k127_4266799_7 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0000000000000000000000000000000002029 132.0
SHD1_k127_4266799_8 2OG-Fe(II) oxygenase superfamily - - - 0.000000000049 72.0
SHD1_k127_4266799_9 - - - - 0.000006756 54.0
SHD1_k127_4287872_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.509e-222 712.0
SHD1_k127_4287872_1 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 532.0
SHD1_k127_4287872_2 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 272.0
SHD1_k127_4287872_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000006086 256.0
SHD1_k127_4287872_4 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000002135 187.0
SHD1_k127_4303158_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1035.0
SHD1_k127_4303158_1 Participates in both transcription termination and antitermination K02600 - - 3.089e-226 709.0
SHD1_k127_4303158_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 526.0
SHD1_k127_4303158_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000002214 202.0
SHD1_k127_4303158_4 RimP C-terminal SH3 domain K09748 - - 0.000000000000000000000000000000000000000001342 161.0
SHD1_k127_4303158_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000003482 146.0
SHD1_k127_4340988_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 530.0
SHD1_k127_4340988_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 457.0
SHD1_k127_4340988_2 PFAM Amidohydrolase 2 K18982 - 5.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 337.0
SHD1_k127_4340988_3 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000002126 216.0
SHD1_k127_4340988_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000006787 217.0
SHD1_k127_4367401_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 4.31e-241 753.0
SHD1_k127_4367401_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 416.0
SHD1_k127_4367401_2 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 378.0
SHD1_k127_4367401_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000002606 226.0
SHD1_k127_4367401_4 GtrA-like protein - - - 0.0006926 49.0
SHD1_k127_4431459_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 364.0
SHD1_k127_4431459_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002318 271.0
SHD1_k127_4431459_2 COG2005 N-terminal domain of molybdenum-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008184 253.0
SHD1_k127_4437945_0 FAD dependent oxidoreductase - - - 0.0 1083.0
SHD1_k127_4437945_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1003.0
SHD1_k127_4437945_10 Domain of unknown function (DUF4845) - - - 0.0000000000000007524 83.0
SHD1_k127_4437945_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 414.0
SHD1_k127_4437945_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 344.0
SHD1_k127_4437945_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 344.0
SHD1_k127_4437945_5 IclR family transcriptional regulator K13641 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001906 266.0
SHD1_k127_4437945_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001328 260.0
SHD1_k127_4437945_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009049 253.0
SHD1_k127_4437945_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000003902 238.0
SHD1_k127_4437945_9 PFAM glutaredoxin 2 - - - 0.000000000000000004877 87.0
SHD1_k127_4439396_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1356.0
SHD1_k127_4439396_1 PFAM extracellular solute-binding protein family 1 K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 553.0
SHD1_k127_4439396_10 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000001977 147.0
SHD1_k127_4439396_11 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000009055 137.0
SHD1_k127_4439396_2 aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006553,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 531.0
SHD1_k127_4439396_3 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 418.0
SHD1_k127_4439396_4 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 412.0
SHD1_k127_4439396_5 Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 387.0
SHD1_k127_4439396_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
SHD1_k127_4439396_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 349.0
SHD1_k127_4439396_8 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008150,GO:0008152,GO:0009015,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001944 283.0
SHD1_k127_4439396_9 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816 - 3.6.3.20 0.000000000000000000000000000000000000000009834 154.0
SHD1_k127_4510786_0 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 515.0
SHD1_k127_4510786_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 421.0
SHD1_k127_4510786_2 Alpha beta hydrolase K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 439.0
SHD1_k127_4510786_3 PFAM NAD-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 391.0
SHD1_k127_4510786_4 COG0665 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 370.0
SHD1_k127_4510786_5 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000007043 158.0
SHD1_k127_4510786_6 proline hydroxylase K07394 - - 0.0000000007546 63.0
SHD1_k127_4523990_0 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 595.0
SHD1_k127_4523990_1 FecR protein - - - 0.000000000000000000000000000000000000006206 163.0
SHD1_k127_4523990_2 Tetratricopeptide repeat - - - 0.0000004717 55.0
SHD1_k127_4575946_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 1.046e-288 914.0
SHD1_k127_4575946_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 617.0
SHD1_k127_4575946_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 435.0
SHD1_k127_4575946_4 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 428.0
SHD1_k127_4575946_5 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001234 253.0
SHD1_k127_4575946_6 AdoMet dependent proline di-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
SHD1_k127_4575946_7 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000004229 221.0
SHD1_k127_4575946_8 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000002811 134.0
SHD1_k127_4575946_9 Protein of unknown function (DUF3460) - - - 0.00000000000269 69.0
SHD1_k127_4615679_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 442.0
SHD1_k127_4615679_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 415.0
SHD1_k127_4615679_2 COG3555 Aspartyl asparaginyl beta-hydroxylase and related dioxygenases K12979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 398.0
SHD1_k127_4615679_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 346.0
SHD1_k127_4615679_4 lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000007238 240.0
SHD1_k127_4615679_5 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000003456 220.0
SHD1_k127_4615679_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000002679 71.0
SHD1_k127_4626784_0 Phospholipase D Active site motif K01115 - 3.1.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 331.0
SHD1_k127_4626784_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002247 256.0
SHD1_k127_4626784_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000009533 194.0
SHD1_k127_4626784_3 Phospholipase D Active site motif K01115 - 3.1.4.4 0.000000000000000000000000000000000000001507 151.0
SHD1_k127_4626925_0 Amino acid adenylation domain - - - 1.597e-304 979.0
SHD1_k127_4626925_1 PFAM Glycoside hydrolase 15-related - - - 3.646e-249 784.0
SHD1_k127_4626925_10 KaiB K08481 - - 0.000000000000000000000000000000000000003553 149.0
SHD1_k127_4626925_11 KaiB K08481 - - 0.000000000000000000000000000001065 127.0
SHD1_k127_4626925_12 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000006107 117.0
SHD1_k127_4626925_13 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000002455 91.0
SHD1_k127_4626925_15 AMP-binding enzyme C-terminal domain K12261,K22133 - 6.2.1.8 0.0000004079 62.0
SHD1_k127_4626925_16 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.0000007916 61.0
SHD1_k127_4626925_2 Pfam:KaiC K08482 - - 4.81e-224 708.0
SHD1_k127_4626925_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 556.0
SHD1_k127_4626925_4 Oxidoreductase family, NAD-binding Rossmann fold K19181 - 1.1.1.292 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 494.0
SHD1_k127_4626925_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 473.0
SHD1_k127_4626925_6 AMP-binding enzyme C-terminal domain K01897,K18660 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 451.0
SHD1_k127_4626925_7 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 403.0
SHD1_k127_4626925_8 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002776 256.0
SHD1_k127_4626925_9 - - - - 0.000000000000000000000000000000000000000000000000000003421 203.0
SHD1_k127_4665316_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 568.0
SHD1_k127_4665316_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 401.0
SHD1_k127_4665316_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 388.0
SHD1_k127_4665316_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000008347 188.0
SHD1_k127_4665316_4 - - - - 0.00000000004215 74.0
SHD1_k127_4665316_5 - - - - 0.00004623 53.0
SHD1_k127_4683077_0 glycosyl transferase family 2 K20444 - - 4.5e-216 689.0
SHD1_k127_4683077_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 1.142e-195 611.0
SHD1_k127_4683077_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 419.0
SHD1_k127_4683077_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 308.0
SHD1_k127_4683077_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000004984 214.0
SHD1_k127_4683077_5 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000001725 78.0
SHD1_k127_4683077_6 Putative zinc-finger - - - 0.000000001543 62.0
SHD1_k127_4687596_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 447.0
SHD1_k127_4687596_1 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 407.0
SHD1_k127_469643_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 571.0
SHD1_k127_469643_1 amino acid transport system, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 448.0
SHD1_k127_469643_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 335.0
SHD1_k127_469643_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000003747 209.0
SHD1_k127_4703663_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1030.0
SHD1_k127_4703663_1 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 5.279e-292 941.0
SHD1_k127_4703663_2 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 5.633e-210 678.0
SHD1_k127_4703663_3 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 596.0
SHD1_k127_4703663_4 alpha amylase catalytic K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 262.0
SHD1_k127_4703663_5 Alpha amylase, catalytic domain K01236 - 3.2.1.141 0.00000000000000000000000003832 113.0
SHD1_k127_4739634_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 385.0
SHD1_k127_4739634_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 348.0
SHD1_k127_4739634_2 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000003442 236.0
SHD1_k127_4783901_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0 1051.0
SHD1_k127_4783901_1 PFAM Prokaryotic protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 484.0
SHD1_k127_4783901_2 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 467.0
SHD1_k127_4783901_3 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 383.0
SHD1_k127_4783901_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000005886 194.0
SHD1_k127_4811204_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1232.0
SHD1_k127_4811204_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 555.0
SHD1_k127_4811204_10 Modulates RecA activity K03565 - - 0.0000000000000000000000001023 113.0
SHD1_k127_4811204_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 428.0
SHD1_k127_4811204_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000002505 211.0
SHD1_k127_4811204_4 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000006744 181.0
SHD1_k127_4811204_5 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000109 179.0
SHD1_k127_4811204_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000009093 180.0
SHD1_k127_4811204_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000001397 168.0
SHD1_k127_4811204_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000003997 168.0
SHD1_k127_4811204_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000004643 146.0
SHD1_k127_4812517_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 546.0
SHD1_k127_4812517_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 394.0
SHD1_k127_4812517_2 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 384.0
SHD1_k127_4812517_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 328.0
SHD1_k127_4812517_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 289.0
SHD1_k127_4812517_5 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000007728 205.0
SHD1_k127_4812517_6 peptidase S16 K07157 - - 0.0000000000000000000000000000000000000000000000002711 185.0
SHD1_k127_4812517_7 ribosomal subunit interface protein K05808 - - 0.000000000000000000000000000000000001658 143.0
SHD1_k127_4821347_0 Transport of potassium into the cell K03549 - - 3.154e-243 767.0
SHD1_k127_4821347_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 510.0
SHD1_k127_4821347_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 400.0
SHD1_k127_4829707_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.693e-204 647.0
SHD1_k127_4829707_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 610.0
SHD1_k127_4829707_10 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 288.0
SHD1_k127_4829707_11 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004291 291.0
SHD1_k127_4829707_12 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003554 273.0
SHD1_k127_4829707_13 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003347 244.0
SHD1_k127_4829707_14 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
SHD1_k127_4829707_15 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000001716 201.0
SHD1_k127_4829707_16 Domain of unknown function (DUF1853) K09977 - - 0.00000000000000000000000000000000000001611 158.0
SHD1_k127_4829707_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000004777 138.0
SHD1_k127_4829707_18 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000564 89.0
SHD1_k127_4829707_2 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 570.0
SHD1_k127_4829707_3 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 548.0
SHD1_k127_4829707_4 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 505.0
SHD1_k127_4829707_5 Oxidoreductase family, C-terminal alpha/beta domain K18067 - 1.3.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 474.0
SHD1_k127_4829707_6 Bifunctional protein RfaE, domain I K21344 - 2.7.1.167 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 400.0
SHD1_k127_4829707_7 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 368.0
SHD1_k127_4829707_8 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 359.0
SHD1_k127_4829707_9 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 298.0
SHD1_k127_4856458_0 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 4.589e-293 914.0
SHD1_k127_4856458_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 391.0
SHD1_k127_4856458_2 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002536 287.0
SHD1_k127_4856458_3 - - - - 0.00000000000000000000000000000000000000000000000000003139 195.0
SHD1_k127_4856458_4 - - - - 0.0000000000000000000000000000188 121.0
SHD1_k127_4856458_5 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000175 122.0
SHD1_k127_4869957_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 417.0
SHD1_k127_4869957_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 314.0
SHD1_k127_4869957_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002809 272.0
SHD1_k127_4869957_4 - - - - 0.000000000000000000000002605 115.0
SHD1_k127_489008_0 Tripartite tricarboxylate transporter TctA family - - - 2.574e-226 710.0
SHD1_k127_489008_1 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 3.795e-198 632.0
SHD1_k127_489008_2 Phenylacetic acid degradation protein PaaY K02617,K08279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 289.0
SHD1_k127_489008_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000002056 201.0
SHD1_k127_489008_4 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000005599 127.0
SHD1_k127_4890758_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 3.633e-242 759.0
SHD1_k127_4890758_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 620.0
SHD1_k127_4890758_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 482.0
SHD1_k127_4890758_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 416.0
SHD1_k127_4890758_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004464 276.0
SHD1_k127_4890758_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004098 256.0
SHD1_k127_4890758_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003005 235.0
SHD1_k127_4890758_7 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000001587 213.0
SHD1_k127_4890758_8 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000007445 97.0
SHD1_k127_4990512_0 ABC transporter K02056 - 3.6.3.17 1.018e-201 642.0
SHD1_k127_4990512_1 CoA-transferase family III - - - 2.295e-194 619.0
SHD1_k127_4990512_10 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000002408 205.0
SHD1_k127_4990512_11 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000005887 183.0
SHD1_k127_4990512_12 P pilus assembly protein porin PapC K07347 - - 0.00000000000000000000000000000000000007228 164.0
SHD1_k127_4990512_13 pilus organization K07346 - - 0.000000000000000000000000000000001264 142.0
SHD1_k127_4990512_14 Cysteine-rich secretory protein family - - - 0.000000000000000000000000001557 119.0
SHD1_k127_4990512_15 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000005437 96.0
SHD1_k127_4990512_16 Spore Coat Protein U domain - - - 0.0000000000000000005672 93.0
SHD1_k127_4990512_17 Spore Coat Protein U domain - - - 0.0000000000171 71.0
SHD1_k127_4990512_2 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 591.0
SHD1_k127_4990512_3 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 523.0
SHD1_k127_4990512_4 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 494.0
SHD1_k127_4990512_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 452.0
SHD1_k127_4990512_6 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 441.0
SHD1_k127_4990512_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 383.0
SHD1_k127_4990512_8 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 360.0
SHD1_k127_4990512_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 284.0
SHD1_k127_4994595_0 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.273e-258 803.0
SHD1_k127_4994595_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000001693 184.0
SHD1_k127_4994595_2 - - - - 0.0000000000000000000000000000000000002722 148.0
SHD1_k127_4994595_3 Protein of unknown function (DUF3426) - - - 0.000000000002435 74.0
SHD1_k127_5009106_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1637.0
SHD1_k127_5009106_1 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 5.281e-300 935.0
SHD1_k127_5009106_11 Carboxylesterase K06999 - - 0.00001148 48.0
SHD1_k127_5009106_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 2.924e-277 893.0
SHD1_k127_5009106_3 Peptidase M16 inactive domain protein K07263 - - 1.475e-274 874.0
SHD1_k127_5009106_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 396.0
SHD1_k127_5009106_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000985 290.0
SHD1_k127_5009106_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000008133 235.0
SHD1_k127_5009106_7 Outer Membrane Lipoprotein - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.000000000000000000000000000000000000000000000196 175.0
SHD1_k127_5009106_8 YCII-related domain - - - 0.0000000000000000003733 91.0
SHD1_k127_5009106_9 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) K03335 - 4.2.1.44 0.00000000000006424 77.0
SHD1_k127_5050946_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1472.0
SHD1_k127_5050946_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 484.0
SHD1_k127_5050946_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 440.0
SHD1_k127_5050946_3 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 331.0
SHD1_k127_5050946_4 carbonate dehydratase activity K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007251 261.0
SHD1_k127_5050946_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000121 268.0
SHD1_k127_5050946_6 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000009992 237.0
SHD1_k127_5050946_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000001213 203.0
SHD1_k127_5050946_8 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000001631 179.0
SHD1_k127_5050946_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001413 90.0
SHD1_k127_5083012_0 ABC-type Fe3 transport system, permease component K02011 - - 2.252e-235 740.0
SHD1_k127_5083012_1 transporter K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 484.0
SHD1_k127_5083012_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 443.0
SHD1_k127_5083012_3 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000003928 104.0
SHD1_k127_5084830_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.988e-206 649.0
SHD1_k127_5084830_1 phenylacetic acid degradation protein paaN - - - 2.146e-204 642.0
SHD1_k127_5084830_2 enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 363.0
SHD1_k127_5084830_3 Phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000000000000000000001722 195.0
SHD1_k127_5084830_4 Ketopantoate reductase K00077 - 1.1.1.169 0.00000000000000000000000000000000001375 138.0
SHD1_k127_5102405_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 567.0
SHD1_k127_5102405_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 409.0
SHD1_k127_5102405_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 396.0
SHD1_k127_5102405_3 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 314.0
SHD1_k127_5102405_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001281 274.0
SHD1_k127_5102405_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000008399 143.0
SHD1_k127_5102405_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000003086 115.0
SHD1_k127_5115560_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.008e-220 697.0
SHD1_k127_5115560_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 611.0
SHD1_k127_5115560_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 482.0
SHD1_k127_5115560_3 Psort location Cytoplasmic, score 8.96 K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000007509 216.0
SHD1_k127_5115560_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000002689 99.0
SHD1_k127_5115560_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000004698 74.0
SHD1_k127_5122575_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.099e-237 752.0
SHD1_k127_5122575_1 Na Pi-cotransporter II-related protein K03324 - - 2.818e-194 627.0
SHD1_k127_5122575_2 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 442.0
SHD1_k127_5122575_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 426.0
SHD1_k127_5122575_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K21196 - 1.13.11.78 0.00000000000000000000000000000000000000000000000000000000001344 229.0
SHD1_k127_5122575_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000001747 192.0
SHD1_k127_5122575_6 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000004526 190.0
SHD1_k127_5122575_7 Binding-protein-dependent transport system inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000002885 181.0
SHD1_k127_5160254_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1267.0
SHD1_k127_5160254_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 447.0
SHD1_k127_5186898_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 605.0
SHD1_k127_5186898_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 446.0
SHD1_k127_5186898_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 293.0
SHD1_k127_5186898_3 - - - - 0.000000000000000000000000000000000000000000000000006158 186.0
SHD1_k127_5186898_4 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.00000000000000000000000000000000000000000000000008252 192.0
SHD1_k127_5186898_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000006359 150.0
SHD1_k127_5186898_6 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000002401 145.0
SHD1_k127_5186898_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.000000000000000000003254 102.0
SHD1_k127_5186898_8 - - - - 0.000000000000009713 76.0
SHD1_k127_5244937_0 FAD linked oxidase domain protein - - - 0.0 1371.0
SHD1_k127_5244937_1 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 589.0
SHD1_k127_5244937_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 484.0
SHD1_k127_5244937_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 415.0
SHD1_k127_5244937_4 ATPase (AAA K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 376.0
SHD1_k127_5244937_5 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 342.0
SHD1_k127_5244937_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000004072 207.0
SHD1_k127_5244937_7 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000003113 83.0
SHD1_k127_5281447_0 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 383.0
SHD1_k127_5281447_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
SHD1_k127_5281447_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000003483 237.0
SHD1_k127_5281447_3 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000009362 227.0
SHD1_k127_5281447_4 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000176 233.0
SHD1_k127_5281447_5 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000001665 167.0
SHD1_k127_5281447_6 Pfam Ankyrin K06867 - - 0.000000000001273 72.0
SHD1_k127_5285544_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1074.0
SHD1_k127_5285544_1 Metallopeptidase family M24 - - - 1.664e-206 649.0
SHD1_k127_5285544_10 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 307.0
SHD1_k127_5285544_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 293.0
SHD1_k127_5285544_12 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000002848 259.0
SHD1_k127_5285544_13 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000001072 191.0
SHD1_k127_5285544_14 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000002698 181.0
SHD1_k127_5285544_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000004636 131.0
SHD1_k127_5285544_16 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000005762 124.0
SHD1_k127_5285544_18 - - - - 0.000000000000003352 81.0
SHD1_k127_5285544_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 540.0
SHD1_k127_5285544_3 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 531.0
SHD1_k127_5285544_4 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 477.0
SHD1_k127_5285544_5 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 476.0
SHD1_k127_5285544_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 365.0
SHD1_k127_5285544_7 Belongs to the binding-protein-dependent transport system permease family K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 347.0
SHD1_k127_5285544_8 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 308.0
SHD1_k127_5285544_9 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 301.0
SHD1_k127_5305700_0 ABC-type Fe3 transport system permease component K02011 - - 1.442e-255 809.0
SHD1_k127_5305700_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 434.0
SHD1_k127_5305700_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000001253 232.0
SHD1_k127_5305700_3 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 0.00000000000000000000000000000000000000000000000000000000000946 212.0
SHD1_k127_5305700_4 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000003037 205.0
SHD1_k127_5305700_5 - - - - 0.0000000000000000001996 103.0
SHD1_k127_5305700_6 ABC-type Fe3 transport system, periplasmic component K02012,K11081 - - 0.0000000000006818 69.0
SHD1_k127_5318704_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.386e-259 818.0
SHD1_k127_5318704_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 552.0
SHD1_k127_5318704_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 333.0
SHD1_k127_5318704_3 Endoribonuclease K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001291 158.0
SHD1_k127_5318704_4 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000001813 154.0
SHD1_k127_5318704_5 Tetratricopeptide repeat - - - 0.00007287 54.0
SHD1_k127_535136_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 6.912e-224 706.0
SHD1_k127_535136_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.766e-199 632.0
SHD1_k127_535136_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 412.0
SHD1_k127_535136_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
SHD1_k127_535136_4 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 344.0
SHD1_k127_535136_5 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000002297 214.0
SHD1_k127_535136_6 protein conserved in bacteria K09937 - - 0.0000000000000004892 80.0
SHD1_k127_5367775_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1124.0
SHD1_k127_5367775_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.109e-220 690.0
SHD1_k127_5367775_10 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000002038 176.0
SHD1_k127_5367775_11 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000359 158.0
SHD1_k127_5367775_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000184 124.0
SHD1_k127_5367775_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 587.0
SHD1_k127_5367775_3 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 486.0
SHD1_k127_5367775_4 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 482.0
SHD1_k127_5367775_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 481.0
SHD1_k127_5367775_6 Two component regulator three Y domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 417.0
SHD1_k127_5367775_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002884 270.0
SHD1_k127_5367775_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000003735 192.0
SHD1_k127_5367775_9 - - - - 0.0000000000000000000000000000000000000000000000004924 181.0
SHD1_k127_5402968_0 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 550.0
SHD1_k127_5402968_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 524.0
SHD1_k127_5402968_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 458.0
SHD1_k127_5402968_3 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 434.0
SHD1_k127_5402968_4 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 370.0
SHD1_k127_5402968_5 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000004777 144.0
SHD1_k127_5471630_0 Belongs to the thiolase family K00632 - 2.3.1.16 3.229e-200 631.0
SHD1_k127_5471630_1 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01031 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 376.0
SHD1_k127_5471630_2 Coenzyme A transferase K01032 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 375.0
SHD1_k127_5471630_3 Protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 351.0
SHD1_k127_5471630_4 helix_turn_helix isocitrate lyase regulation K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 332.0
SHD1_k127_5471630_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
SHD1_k127_5471630_6 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
SHD1_k127_5471630_7 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000002843 214.0
SHD1_k127_5471630_8 protocatechuate 3,4-dioxygenase, alpha K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000003169 192.0
SHD1_k127_5486493_0 ABC transporter K06020 - 3.6.3.25 7.101e-236 736.0
SHD1_k127_5486493_1 Adenylate - - - 4.621e-199 660.0
SHD1_k127_5486493_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.28e-198 628.0
SHD1_k127_5486493_3 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000008565 198.0
SHD1_k127_5486493_4 Acetyltransferase (GNAT) family K06976 - - 0.00000000000000000000000000000000000000000000000005675 187.0
SHD1_k127_5486493_5 ABC transporter, ATP-binding protein K06020 - 3.6.3.25 0.00000000000000000000000000000000000000000000002289 170.0
SHD1_k127_5486493_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000006489 53.0
SHD1_k127_550310_0 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002072 253.0
SHD1_k127_550310_1 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009322 241.0
SHD1_k127_550310_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000003393 236.0
SHD1_k127_550310_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000004659 152.0
SHD1_k127_550310_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000001424 77.0
SHD1_k127_567121_0 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 406.0
SHD1_k127_567121_1 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 397.0
SHD1_k127_567121_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 377.0
SHD1_k127_567121_3 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 346.0
SHD1_k127_567121_4 - - - - 0.00000000000000000000000000006866 124.0
SHD1_k127_567121_5 - - - - 0.0000000003068 64.0
SHD1_k127_58166_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.393e-297 926.0
SHD1_k127_58166_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.537e-269 839.0
SHD1_k127_58166_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002283 260.0
SHD1_k127_58166_11 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000002411 233.0
SHD1_k127_58166_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000001852 218.0
SHD1_k127_58166_13 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000003012 212.0
SHD1_k127_58166_14 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000001202 202.0
SHD1_k127_58166_15 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000002 207.0
SHD1_k127_58166_16 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000007055 160.0
SHD1_k127_58166_17 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000008821 157.0
SHD1_k127_58166_18 - - - - 0.0000000000000000000000000000004502 132.0
SHD1_k127_58166_19 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000004659 126.0
SHD1_k127_58166_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 590.0
SHD1_k127_58166_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 568.0
SHD1_k127_58166_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
SHD1_k127_58166_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 406.0
SHD1_k127_58166_6 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 389.0
SHD1_k127_58166_7 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 361.0
SHD1_k127_58166_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 350.0
SHD1_k127_58166_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 323.0
SHD1_k127_61276_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1112.0
SHD1_k127_61276_1 ABC transporter - - - 1.334e-260 812.0
SHD1_k127_61276_10 Universal stress protein - - - 0.0007563 44.0
SHD1_k127_61276_2 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
SHD1_k127_61276_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
SHD1_k127_61276_4 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006983 254.0
SHD1_k127_61276_5 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000001458 168.0
SHD1_k127_61276_6 transcriptional regulator, XRE family - - - 0.00000000000000000000000000000000000000001052 162.0
SHD1_k127_61276_7 - - - - 0.000000007006 62.0
SHD1_k127_61276_8 - - - - 0.00000001842 56.0
SHD1_k127_61276_9 - K19168 - - 0.000003319 56.0
SHD1_k127_630092_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1274.0
SHD1_k127_630092_1 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 477.0
SHD1_k127_630092_2 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
SHD1_k127_630092_3 Carboxylesterase family K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000593 230.0
SHD1_k127_630092_4 - - - - 0.0000000000000000000000000000000000000000000002588 175.0
SHD1_k127_630092_5 TPM domain K06872 - - 0.00000000000000000000000000000000000002592 147.0
SHD1_k127_630092_6 Methyltransferase domain - - - 0.00000000000000003778 91.0
SHD1_k127_630092_7 Thiol-disulfide isomerase K00384 - 1.8.1.9 0.0002737 51.0
SHD1_k127_634300_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1446.0
SHD1_k127_634300_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 498.0
SHD1_k127_6425_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1530.0
SHD1_k127_6425_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 557.0
SHD1_k127_6425_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 518.0
SHD1_k127_6425_3 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 369.0
SHD1_k127_6425_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009635 282.0
SHD1_k127_6425_5 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000154 151.0
SHD1_k127_66347_0 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 608.0
SHD1_k127_66347_1 glycolate oxidase iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 531.0
SHD1_k127_66347_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009204 282.0
SHD1_k127_66347_11 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001612 269.0
SHD1_k127_66347_12 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000004729 238.0
SHD1_k127_66347_13 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000006241 233.0
SHD1_k127_66347_14 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000006604 207.0
SHD1_k127_66347_15 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000008501 208.0
SHD1_k127_66347_16 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000006677 115.0
SHD1_k127_66347_17 preprotein translocase K03075 - - 0.0000000000000000001602 90.0
SHD1_k127_66347_18 Heavy-metal resistance - - - 0.00000000003041 70.0
SHD1_k127_66347_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008685,GO:0009058,GO:0009987,GO:0016114,GO:0016829,GO:0016849,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0051483,GO:0071704,GO:1901576 2.7.7.60,4.6.1.12 0.00002135 48.0
SHD1_k127_66347_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 475.0
SHD1_k127_66347_3 abc transporter K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 467.0
SHD1_k127_66347_4 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 453.0
SHD1_k127_66347_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 417.0
SHD1_k127_66347_6 Histidine kinase K20975 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 367.0
SHD1_k127_66347_7 PFAM response regulator receiver K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 346.0
SHD1_k127_66347_8 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 309.0
SHD1_k127_66347_9 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 308.0
SHD1_k127_716997_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.53e-301 943.0
SHD1_k127_716997_1 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 441.0
SHD1_k127_716997_10 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000002068 188.0
SHD1_k127_716997_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000001532 186.0
SHD1_k127_716997_12 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000001229 165.0
SHD1_k127_716997_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000005806 122.0
SHD1_k127_716997_14 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000916 83.0
SHD1_k127_716997_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 391.0
SHD1_k127_716997_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 385.0
SHD1_k127_716997_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 370.0
SHD1_k127_716997_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 364.0
SHD1_k127_716997_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 348.0
SHD1_k127_716997_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 316.0
SHD1_k127_716997_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003572 281.0
SHD1_k127_716997_9 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000001136 246.0
SHD1_k127_725057_0 AcyL-CoA dehydrogenase K06445 - - 0.0 1102.0
SHD1_k127_725057_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 366.0
SHD1_k127_725057_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003692 251.0
SHD1_k127_725057_3 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000005507 109.0
SHD1_k127_739546_0 PFAM extracellular solute-binding protein, family 5 K02035,K13889 - - 1.219e-196 619.0
SHD1_k127_739546_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K13890 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 511.0
SHD1_k127_739546_2 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 486.0
SHD1_k127_739546_3 PFAM binding-protein-dependent transport systems inner membrane component K13891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 474.0
SHD1_k127_739546_4 - - - - 0.0000000000000000000000000000000000000000000000000848 183.0
SHD1_k127_739546_5 carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000002854 94.0
SHD1_k127_755491_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.458e-201 635.0
SHD1_k127_755491_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 2.518e-197 621.0
SHD1_k127_755491_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 452.0
SHD1_k127_755491_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 427.0
SHD1_k127_755491_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 359.0
SHD1_k127_755491_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 330.0
SHD1_k127_755491_6 Arm DNA-binding domain K14059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006752 287.0
SHD1_k127_755491_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000009384 139.0
SHD1_k127_755491_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000704 115.0
SHD1_k127_832168_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1263.0
SHD1_k127_832168_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.143e-233 730.0
SHD1_k127_832168_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 548.0
SHD1_k127_832168_3 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 410.0
SHD1_k127_905003_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1527.0
SHD1_k127_905003_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789 - - 0.0 1479.0
SHD1_k127_905003_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000003313 213.0
SHD1_k127_905003_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000008567 94.0
SHD1_k127_905003_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.689e-235 732.0
SHD1_k127_905003_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.107e-200 629.0
SHD1_k127_905003_4 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 584.0
SHD1_k127_905003_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 514.0
SHD1_k127_905003_6 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 458.0
SHD1_k127_905003_7 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 392.0
SHD1_k127_905003_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 376.0
SHD1_k127_905003_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
SHD1_k127_947872_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01006,K01007,K21787 - 2.7.9.1,2.7.9.2 0.0 1219.0
SHD1_k127_947872_1 abc transporter K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 463.0
SHD1_k127_947872_2 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 464.0
SHD1_k127_947872_3 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 449.0
SHD1_k127_947872_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 434.0
SHD1_k127_947872_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 414.0
SHD1_k127_947872_6 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 411.0
SHD1_k127_947872_7 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000006068 198.0
SHD1_k127_947872_8 Phosphopantetheine attachment site - - - 0.0000000000000000001468 91.0
SHD1_k127_947872_9 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000003608 69.0
SHD1_k127_953820_0 Required for chromosome condensation and partitioning K03529 - - 1.658e-291 937.0
SHD1_k127_953820_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.617e-277 873.0
SHD1_k127_953820_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 391.0
SHD1_k127_953820_3 Transcriptional regulator, LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
SHD1_k127_953820_4 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 340.0
SHD1_k127_953820_5 haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000001294 199.0
SHD1_k127_953820_6 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000003311 201.0
SHD1_k127_954449_0 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 523.0
SHD1_k127_954449_1 surface antigen K07278 - - 0.0000000000000000000000000000000000000001103 153.0
SHD1_k127_954449_2 Alg9-like mannosyltransferase family K05286 - - 0.0005173 52.0
SHD1_k127_959957_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.894e-301 934.0
SHD1_k127_959957_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 4.9e-301 952.0
SHD1_k127_959957_2 CoA binding domain - - - 2.841e-287 891.0
SHD1_k127_959957_3 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 2.589e-268 835.0
SHD1_k127_959957_4 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 2.349e-251 778.0
SHD1_k127_959957_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
SHD1_k127_96758_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00821 - 2.6.1.11,2.6.1.17,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 600.0
SHD1_k127_96758_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 328.0
SHD1_k127_96758_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 332.0
SHD1_k127_96758_3 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 309.0
SHD1_k127_96758_4 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
SHD1_k127_97185_0 Peptidase family M3 K01392 - 3.4.24.15 1.479e-220 724.0
SHD1_k127_97185_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.692e-194 626.0
SHD1_k127_97185_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 601.0
SHD1_k127_97185_3 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000424 240.0
SHD1_k127_97185_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000427 173.0
SHD1_k127_97185_5 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000004912 77.0
SHD1_k127_978661_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.949e-227 715.0
SHD1_k127_978661_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 472.0
SHD1_k127_978661_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 434.0
SHD1_k127_978661_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 332.0
SHD1_k127_978661_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 306.0
SHD1_k127_978661_5 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000005507 220.0
SHD1_k127_978661_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000004672 119.0
SHD1_k127_978661_7 - - - - 0.00008883 52.0
SHD1_k127_985305_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 1.988e-213 681.0
SHD1_k127_985305_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 523.0
SHD1_k127_985305_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 327.0
SHD1_k127_985305_3 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000008342 192.0
SHD1_k127_985305_4 Protein of unknown function (DUF2783) - - - 0.00000000000000000001133 95.0
SHD1_k127_988795_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.253e-199 638.0
SHD1_k127_988795_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 338.0
SHD1_k127_988795_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000001639 164.0
SHD1_k127_988795_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000001342 160.0
SHD1_k127_988795_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000002558 132.0
SHD1_k127_988795_5 Cytochrome C assembly protein - - - 0.000000000007887 73.0
SHD1_k127_990818_0 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004217 263.0
SHD1_k127_990818_1 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000588 203.0
SHD1_k127_990818_2 PFAM PRC-barrel domain - - - 0.00000000000000000000000000000000000000000004927 172.0
SHD1_k127_990818_3 Protein of unknown function (DUF3309) - - - 0.00000000000000000009419 89.0
SHD1_k127_990818_4 - - - - 0.000000000000000006496 89.0