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Overview

ID MAG03367
Name SHD1_bin.4
Sample SMP0082
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family Gemmatimonadaceae
Genus UBA4720
Species
Assembly information
Completeness (%) 79.28
Contamination (%) 3.91
GC content (%) 59.0
N50 (bp) 5,516
Genome size (bp) 2,778,216

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2668

Gene name Description KEGG GOs EC E-value Score Sequence
SHD1_k127_10157_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.218e-223 724.0
SHD1_k127_10157_1 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000005968 179.0
SHD1_k127_1017692_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 591.0
SHD1_k127_1017692_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000118 116.0
SHD1_k127_1017692_2 ArgE DapE Acy1 family protein K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000002006 78.0
SHD1_k127_102116_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1406.0
SHD1_k127_102116_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 494.0
SHD1_k127_102116_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 462.0
SHD1_k127_102116_3 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000001083 196.0
SHD1_k127_102116_4 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000002858 178.0
SHD1_k127_1027007_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 488.0
SHD1_k127_1027007_1 PFAM Ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 480.0
SHD1_k127_1027007_2 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 398.0
SHD1_k127_1027007_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 313.0
SHD1_k127_1027007_4 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006586 258.0
SHD1_k127_1027007_5 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000002881 177.0
SHD1_k127_1027007_7 Methyltransferase type 11 - - - 0.00000000000000000000000001827 116.0
SHD1_k127_1027007_8 Predicted membrane protein (DUF2339) - - - 0.000000000000000000001809 110.0
SHD1_k127_1041218_0 Acts as a magnesium transporter K06213 - - 1.065e-195 622.0
SHD1_k127_1041218_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000005843 112.0
SHD1_k127_1041218_2 mercury ion transmembrane transporter activity K07213 - - 0.0000004094 57.0
SHD1_k127_104281_0 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 517.0
SHD1_k127_104281_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 385.0
SHD1_k127_104281_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000003421 130.0
SHD1_k127_104281_3 HupF/HypC family K04653 - - 0.0000000000000000000000004098 109.0
SHD1_k127_104281_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.0001492 49.0
SHD1_k127_1043333_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1019.0
SHD1_k127_1043333_1 Thiolase, C-terminal domain K02615 - 2.3.1.174,2.3.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 546.0
SHD1_k127_1043333_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 395.0
SHD1_k127_1043333_3 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 313.0
SHD1_k127_1046925_0 ABC transporter C-terminal domain K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 533.0
SHD1_k127_1046925_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 442.0
SHD1_k127_1052867_0 Transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with metabolic process K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 398.0
SHD1_k127_1052867_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
SHD1_k127_1052867_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
SHD1_k127_1052867_3 - - - - 0.000000000000000000000000000000002063 139.0
SHD1_k127_1052867_4 - - - - 0.00000000002599 66.0
SHD1_k127_1061200_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 377.0
SHD1_k127_1061200_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 354.0
SHD1_k127_1061200_10 - - - - 0.00000000000000000000000306 112.0
SHD1_k127_1061200_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 342.0
SHD1_k127_1061200_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004059 267.0
SHD1_k127_1061200_4 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 256.0
SHD1_k127_1061200_5 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
SHD1_k127_1061200_6 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000000000000000000000000000000006776 205.0
SHD1_k127_1061200_7 Fe-S metabolism associated domain K02426 - - 0.00000000000000000000000000000000000000000000000000000002847 199.0
SHD1_k127_1061200_8 - - - - 0.000000000000000000000000000000000000000000001843 169.0
SHD1_k127_1061200_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000003198 160.0
SHD1_k127_108329_0 Uncharacterised conserved protein (DUF2156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
SHD1_k127_108329_1 IMP dehydrogenase activity K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
SHD1_k127_108329_2 Cysteine-rich CPXCG - - - 0.000000000000000000002944 94.0
SHD1_k127_108329_3 Uncharacterised conserved protein (DUF2156) - - - 0.000000000001243 70.0
SHD1_k127_108329_4 - - - - 0.00000000004021 70.0
SHD1_k127_1098678_0 - - - - 1.23e-198 643.0
SHD1_k127_110149_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1097.0
SHD1_k127_110149_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 558.0
SHD1_k127_110149_2 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 560.0
SHD1_k127_110149_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 463.0
SHD1_k127_110149_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 401.0
SHD1_k127_110149_5 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
SHD1_k127_110149_6 - - - - 0.000000000000000000000000007154 110.0
SHD1_k127_110149_7 - - - - 0.00000000000002333 76.0
SHD1_k127_1106112_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.182e-254 792.0
SHD1_k127_1106112_1 - - - - 0.000000006891 64.0
SHD1_k127_1127455_0 von Willebrand factor (vWF) type A domain - - - 7.847e-228 710.0
SHD1_k127_1127455_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 297.0
SHD1_k127_1127455_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000006795 128.0
SHD1_k127_1140695_0 Carbamoyltransferase C-terminus K00612 - - 2.609e-282 879.0
SHD1_k127_1140695_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 425.0
SHD1_k127_1140695_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001295 276.0
SHD1_k127_1140695_3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000002828 262.0
SHD1_k127_1140695_4 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000469 162.0
SHD1_k127_1140695_5 - - - - 0.00000000000000000000004062 107.0
SHD1_k127_1140695_6 - - - - 0.0000000000000000114 85.0
SHD1_k127_1151407_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 560.0
SHD1_k127_1151407_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 449.0
SHD1_k127_1151407_2 Late embryogenesis abundant protein - - - 0.000000000000000000000000000000000000000000000000000002469 194.0
SHD1_k127_115989_0 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
SHD1_k127_115989_1 - - - - 0.00000000000000000000000000000000000000000000000000004402 198.0
SHD1_k127_115989_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000002863 160.0
SHD1_k127_115989_3 COG3668 Plasmid stabilization system protein - - - 0.00000000000000000000000797 102.0
SHD1_k127_115989_4 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000003551 100.0
SHD1_k127_115989_5 Putative adhesin - - - 0.000000000000000005564 95.0
SHD1_k127_1186936_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000001248 228.0
SHD1_k127_1186936_1 Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000001619 171.0
SHD1_k127_1196013_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1238.0
SHD1_k127_1196013_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 584.0
SHD1_k127_1196013_2 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 434.0
SHD1_k127_1196013_3 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000003509 224.0
SHD1_k127_1196013_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000008023 211.0
SHD1_k127_1196013_5 FixH - - - 0.0000000000000000000001574 106.0
SHD1_k127_1196013_6 Polymer-forming cytoskeletal - - - 0.000001003 53.0
SHD1_k127_1196013_7 Cbb3-type cytochrome oxidase K00407 - - 0.00005102 52.0
SHD1_k127_122312_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 7.714e-304 952.0
SHD1_k127_122312_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 462.0
SHD1_k127_122312_2 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000483 289.0
SHD1_k127_122312_3 Transcriptional regulator K07729 - - 0.000000000000001426 78.0
SHD1_k127_122312_5 - - - - 0.00006319 49.0
SHD1_k127_122312_6 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000737 48.0
SHD1_k127_122717_0 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 502.0
SHD1_k127_122717_1 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002211 258.0
SHD1_k127_122717_2 Tetratricopeptide repeat - - - 0.0000000000000000000004243 101.0
SHD1_k127_122717_3 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00008238 49.0
SHD1_k127_1227295_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.948e-228 715.0
SHD1_k127_1227295_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 321.0
SHD1_k127_1235205_0 SnoaL-like domain - - - 0.000000000000000000000000000000000000001655 153.0
SHD1_k127_1235205_1 - - - - 0.00000000000000002529 83.0
SHD1_k127_1235205_2 - - - - 0.00000000007203 70.0
SHD1_k127_1235205_3 PFAM Forkhead-associated protein - - - 0.000000003603 64.0
SHD1_k127_1241505_0 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 305.0
SHD1_k127_1241505_1 Capsule assembly protein Wzi - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004434 265.0
SHD1_k127_1241505_2 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000000000689 221.0
SHD1_k127_124694_0 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 292.0
SHD1_k127_124694_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
SHD1_k127_124694_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
SHD1_k127_124694_3 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000008513 188.0
SHD1_k127_124694_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000137 166.0
SHD1_k127_124694_5 - - - - 0.0000000000000000000000000001812 122.0
SHD1_k127_124694_6 - - - - 0.0000000001271 64.0
SHD1_k127_1264070_0 DEAD/H associated K03724 - - 6.942e-312 969.0
SHD1_k127_1264070_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 289.0
SHD1_k127_1264070_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000002071 92.0
SHD1_k127_1265647_0 Glycosyl hydrolases family 18 - - - 0.0 1153.0
SHD1_k127_1265647_1 Penicillin amidase K01434 - 3.5.1.11 4.276e-279 876.0
SHD1_k127_1265647_2 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 385.0
SHD1_k127_1265647_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
SHD1_k127_1265647_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000004972 179.0
SHD1_k127_1265647_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000003333 179.0
SHD1_k127_1265647_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000001909 124.0
SHD1_k127_1265647_7 Cupin domain - - - 0.0001318 46.0
SHD1_k127_1265647_8 gag-polyprotein putative aspartyl protease - - - 0.0003521 51.0
SHD1_k127_126810_0 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 1.674e-246 789.0
SHD1_k127_126810_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 339.0
SHD1_k127_126810_2 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000004472 155.0
SHD1_k127_126810_3 ATPase activity K10112 - - 0.00000000000000000000000000000000001354 141.0
SHD1_k127_126810_4 Transglycosylase associated protein - - - 0.00000000000000000000000000000002154 128.0
SHD1_k127_126810_5 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000003194 130.0
SHD1_k127_126810_6 PFAM S23 ribosomal protein - - - 0.0000001529 59.0
SHD1_k127_1273829_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 558.0
SHD1_k127_1273829_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 337.0
SHD1_k127_1273829_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 308.0
SHD1_k127_1273829_3 - - - - 0.000000000000000000000000000000000000000000000000000000007584 212.0
SHD1_k127_1273829_4 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
SHD1_k127_1273829_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000006386 214.0
SHD1_k127_1273829_6 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000007697 187.0
SHD1_k127_1273829_7 - - - - 0.000000000000000000000007722 113.0
SHD1_k127_1276479_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 343.0
SHD1_k127_1276479_1 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
SHD1_k127_1276479_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000008235 184.0
SHD1_k127_1276479_4 - - - - 0.00000000000000000000000004088 110.0
SHD1_k127_1277926_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 559.0
SHD1_k127_1277926_1 Uncharacterised protein family (UPF0182) K09118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 321.0
SHD1_k127_1277926_2 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001193 282.0
SHD1_k127_1277926_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00001458 51.0
SHD1_k127_1283022_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 1.052e-312 969.0
SHD1_k127_1283022_1 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 373.0
SHD1_k127_1283022_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 288.0
SHD1_k127_1283022_3 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000001792 220.0
SHD1_k127_1283022_4 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000005674 59.0
SHD1_k127_1286790_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 437.0
SHD1_k127_1286790_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
SHD1_k127_1286790_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 314.0
SHD1_k127_1286790_3 Protein of unknown function (DUF721) - - - 0.0000000000000000000001653 102.0
SHD1_k127_1289393_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.442e-235 743.0
SHD1_k127_1289393_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001393 228.0
SHD1_k127_1289393_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000007746 132.0
SHD1_k127_1302651_0 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000011 241.0
SHD1_k127_1302651_1 - - - - 0.00000000000000000000000000000000000000000000000345 175.0
SHD1_k127_1302651_2 VKc - - - 0.0000000000000000000497 96.0
SHD1_k127_1302651_3 DSBA-like thioredoxin domain - - - 0.00000000000000008583 81.0
SHD1_k127_1321550_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 512.0
SHD1_k127_1321550_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 465.0
SHD1_k127_1321550_2 - - - - 0.0005415 48.0
SHD1_k127_1327911_0 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002288 261.0
SHD1_k127_1327911_1 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000004867 143.0
SHD1_k127_1327911_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000001393 93.0
SHD1_k127_1359327_0 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 565.0
SHD1_k127_1359327_1 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 350.0
SHD1_k127_1359327_2 tryptophan 2,3-dioxygenase activity K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 303.0
SHD1_k127_1359327_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000006671 205.0
SHD1_k127_1380638_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003188 301.0
SHD1_k127_1380638_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000007856 199.0
SHD1_k127_1380638_2 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.00003737 50.0
SHD1_k127_1384111_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.479e-313 971.0
SHD1_k127_1384111_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.396e-251 778.0
SHD1_k127_1384111_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 432.0
SHD1_k127_1384111_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
SHD1_k127_1386025_0 cellulose binding - - - 0.0 1172.0
SHD1_k127_1386025_1 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 353.0
SHD1_k127_1386025_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
SHD1_k127_1386025_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000002033 189.0
SHD1_k127_1386025_4 - - - - 0.000000000000000000000000000000000000001515 156.0
SHD1_k127_1386025_5 - - - - 0.00000000000000000000000000000000004286 144.0
SHD1_k127_1398759_0 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 558.0
SHD1_k127_1398759_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000005213 209.0
SHD1_k127_1398759_2 - - - - 0.00000000000000001695 89.0
SHD1_k127_1406868_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 355.0
SHD1_k127_1406868_1 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000001777 122.0
SHD1_k127_1407951_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 2.268e-305 940.0
SHD1_k127_1412034_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 537.0
SHD1_k127_1412034_1 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 451.0
SHD1_k127_1412034_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000001074 167.0
SHD1_k127_1412034_3 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000006579 154.0
SHD1_k127_1412034_4 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000006205 98.0
SHD1_k127_1412034_5 Protein of unknown function (DUF4235) - - - 0.00000000001028 69.0
SHD1_k127_1416902_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 2.174e-217 685.0
SHD1_k127_1416902_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 544.0
SHD1_k127_1425233_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 4.125e-264 821.0
SHD1_k127_1425233_1 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007883 281.0
SHD1_k127_1427322_0 Atp-dependent helicase - - - 0.0 1233.0
SHD1_k127_1427322_1 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 574.0
SHD1_k127_1427322_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000008974 188.0
SHD1_k127_1427322_3 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271,K03272,K03525,K12961 GO:0003674,GO:0005488,GO:0005515,GO:0006275,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010556,GO:0010557,GO:0010604,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032298,GO:0042802,GO:0045740,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0060255,GO:0065007,GO:0080090,GO:0090329,GO:2000105,GO:2000112 2.7.1.167,2.7.1.33,2.7.7.70,5.3.1.28 0.000000000000000000000000000000000000000000000002059 179.0
SHD1_k127_1427322_4 Putative esterase - - - 0.00008191 48.0
SHD1_k127_1432891_0 TonB-dependent receptor - - - 5.141e-293 932.0
SHD1_k127_1432891_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.292e-257 805.0
SHD1_k127_1432891_2 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 355.0
SHD1_k127_1432891_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 326.0
SHD1_k127_1432891_4 TonB-dependent Receptor Plug K16092 - - 0.000008002 54.0
SHD1_k127_1440734_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 607.0
SHD1_k127_1440734_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 317.0
SHD1_k127_1440734_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000001897 211.0
SHD1_k127_1440734_3 STAS domain K04749 - - 0.000000000000000000000000000000000000000000000000000003971 192.0
SHD1_k127_1440734_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000006899 192.0
SHD1_k127_1440734_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000000000005779 158.0
SHD1_k127_1452698_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 456.0
SHD1_k127_1452698_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003134 280.0
SHD1_k127_1452698_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005137 269.0
SHD1_k127_1452698_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000009146 221.0
SHD1_k127_1452698_4 PFAM DNA RNA tunnel of bacterial DNA dependent RNA polymerase - - - 0.0000000000000000000000000000000000000000000000000000005541 195.0
SHD1_k127_1452698_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000001513 178.0
SHD1_k127_1452698_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000001251 136.0
SHD1_k127_1452698_7 lactoylglutathione lyase activity - - - 0.00000000000000000002426 93.0
SHD1_k127_1452698_8 Ricin-type beta-trefoil - - - 0.000000001476 70.0
SHD1_k127_1461175_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1637.0
SHD1_k127_1462124_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 578.0
SHD1_k127_1462124_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 553.0
SHD1_k127_1462124_2 Cell division protein FtsQ K03589 - - 0.0000000009855 60.0
SHD1_k127_1462747_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1648.0
SHD1_k127_1463788_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.66e-215 675.0
SHD1_k127_1463788_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 395.0
SHD1_k127_1463788_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 375.0
SHD1_k127_1463788_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000232 295.0
SHD1_k127_1463788_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000002506 276.0
SHD1_k127_1463788_5 Transcriptional regulatory protein, C terminal K07665 - - 0.0000000000000000000000000000000001313 133.0
SHD1_k127_1463788_6 - - - - 0.0000000000000000000000000000001204 125.0
SHD1_k127_1463788_7 Septum formation initiator K05589 - - 0.0000000000000000008653 89.0
SHD1_k127_1470855_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 424.0
SHD1_k127_1470855_1 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 302.0
SHD1_k127_1479902_0 Putative modulator of DNA gyrase K03568 - - 7.857e-235 737.0
SHD1_k127_1479902_1 Putative modulator of DNA gyrase - - - 4.141e-201 637.0
SHD1_k127_1479902_2 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 490.0
SHD1_k127_1479902_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007418 262.0
SHD1_k127_1479902_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000009307 102.0
SHD1_k127_1488247_0 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 338.0
SHD1_k127_1488247_1 PFAM HhH-GPD superfamily base excision DNA repair protein K01247 - 3.2.2.21 0.0000000000000000000001276 100.0
SHD1_k127_1499818_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 361.0
SHD1_k127_1499818_1 - - - - 0.00000000000000000000000000000000000000000000000000000000008246 211.0
SHD1_k127_1499818_2 Acetoacetate metabolism regulatory protein atoC K02481 - - 0.000003529 51.0
SHD1_k127_1502081_0 Bacterial protein of unknown function (DUF885) - - - 1.594e-227 721.0
SHD1_k127_1502081_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 378.0
SHD1_k127_1502081_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 288.0
SHD1_k127_1502081_4 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity K13991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - 0.00003169 54.0
SHD1_k127_1504339_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1290.0
SHD1_k127_1504339_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 440.0
SHD1_k127_1504339_2 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 384.0
SHD1_k127_1504339_3 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 289.0
SHD1_k127_1504339_4 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000287 177.0
SHD1_k127_1504339_5 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000007038 126.0
SHD1_k127_1522256_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 318.0
SHD1_k127_1522256_1 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000001648 228.0
SHD1_k127_1522256_2 Amidohydrolase family - - - 0.00000000194 61.0
SHD1_k127_1530539_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.989e-218 686.0
SHD1_k127_1530539_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 510.0
SHD1_k127_1530539_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 400.0
SHD1_k127_1530539_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 303.0
SHD1_k127_1530539_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
SHD1_k127_1530539_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000008458 155.0
SHD1_k127_1555523_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 439.0
SHD1_k127_1555523_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 430.0
SHD1_k127_1555523_2 SprT-like family - - - 0.00000000000000000000000000000000000000000000000000000000004689 213.0
SHD1_k127_1561700_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 408.0
SHD1_k127_1561700_1 EAL domain K13950,K21025 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000002257 253.0
SHD1_k127_1561700_2 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
SHD1_k127_1561700_3 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000001284 202.0
SHD1_k127_1561700_4 EAL domain - - - 0.000000000000000000000000000000000000000000000000000006728 207.0
SHD1_k127_1561700_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000002871 172.0
SHD1_k127_1565729_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000003966 160.0
SHD1_k127_1565729_1 O-antigen polysaccharide polymerase Wzy - - - 0.0000000000000000000000000001488 131.0
SHD1_k127_1565729_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000001913 111.0
SHD1_k127_1565729_3 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000132 100.0
SHD1_k127_1565729_4 transferase activity, transferring glycosyl groups K00786 - - 0.00000000004101 66.0
SHD1_k127_1565729_5 transferase activity, transferring glycosyl groups K00786 - - 0.0000000003144 63.0
SHD1_k127_1574383_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 437.0
SHD1_k127_1574383_1 Transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with metabolic process K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 415.0
SHD1_k127_1574383_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 345.0
SHD1_k127_1574383_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000004073 257.0
SHD1_k127_1574383_4 - - - - 0.000000000000000000000000000004891 130.0
SHD1_k127_1574383_5 - - - - 0.000000000000002482 79.0
SHD1_k127_1574383_6 - - - - 0.00000000006736 65.0
SHD1_k127_157921_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000065 211.0
SHD1_k127_157921_1 LysM domain - - - 0.0000000000002998 82.0
SHD1_k127_157921_2 cytochrome complex assembly - - - 0.0000000000003345 79.0
SHD1_k127_157921_3 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000147 76.0
SHD1_k127_1582737_0 WD40-like Beta Propeller Repeat - - - 5.416e-306 968.0
SHD1_k127_1582737_1 Protein kinase domain K12132 - 2.7.11.1 1.025e-201 657.0
SHD1_k127_1582737_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000408 215.0
SHD1_k127_1582737_3 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000003378 141.0
SHD1_k127_1582737_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000001014 103.0
SHD1_k127_1582737_5 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0001944 45.0
SHD1_k127_1584046_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 571.0
SHD1_k127_1584046_1 Phosphoribosylglycinamide synthetase, C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 544.0
SHD1_k127_1584046_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003615 235.0
SHD1_k127_1584046_3 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000009898 180.0
SHD1_k127_1584046_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000003328 148.0
SHD1_k127_1584046_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000691 138.0
SHD1_k127_1584046_6 - - - - 0.000000000000000000000003706 105.0
SHD1_k127_1584046_7 L-alpha-amino acid transmembrane transport K11584 GO:0002376,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0006928,GO:0006950,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015203,GO:0015291,GO:0015297,GO:0015318,GO:0015695,GO:0015696,GO:0015711,GO:0015807,GO:0015839,GO:0015846,GO:0015849,GO:0016020,GO:0016021,GO:0016043,GO:0016477,GO:0019752,GO:0022607,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0040011,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0048870,GO:0050896,GO:0050900,GO:0051179,GO:0051234,GO:0051674,GO:0055085,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0098656,GO:1901564,GO:1902047,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000003438 101.0
SHD1_k127_1584046_8 Anti-sigma-K factor rskA - - - 0.00000000004227 74.0
SHD1_k127_1584046_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000004072 68.0
SHD1_k127_158717_0 Zinc carboxypeptidase K14054 - - 0.0 1195.0
SHD1_k127_158717_1 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 385.0
SHD1_k127_158717_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 358.0
SHD1_k127_158717_3 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 347.0
SHD1_k127_158717_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001765 256.0
SHD1_k127_158717_5 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000001421 220.0
SHD1_k127_158717_6 permease - - - 0.00000000000000000000000000000000000000000000000000000000006433 211.0
SHD1_k127_158717_7 HEAT repeats - - - 0.0000000000000000000000000000000000000005276 162.0
SHD1_k127_158717_9 LemA family K03744 - - 0.000000000000000000000000000003836 128.0
SHD1_k127_1593982_0 Phosphoribosylglycinamide synthetase, C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 535.0
SHD1_k127_1593982_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000004782 114.0
SHD1_k127_1593982_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000001585 62.0
SHD1_k127_1600835_0 IMP dehydrogenase activity K03281 - - 1.789e-238 753.0
SHD1_k127_1600835_1 Uncharacterised conserved protein (DUF2156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 394.0
SHD1_k127_1600835_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 341.0
SHD1_k127_1600835_3 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000007179 228.0
SHD1_k127_1600835_4 Cysteine-rich CPXCG - - - 0.000000000000000000001912 97.0
SHD1_k127_1612701_0 coagulation factor 5 8 type - - - 3.442e-285 912.0
SHD1_k127_1612701_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 2.923e-209 658.0
SHD1_k127_1612701_2 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 347.0
SHD1_k127_1612701_3 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 349.0
SHD1_k127_1612701_4 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000002233 188.0
SHD1_k127_1613701_0 peptidase K01415,K07386 - 3.4.24.71 2.046e-210 676.0
SHD1_k127_1613701_1 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000005958 187.0
SHD1_k127_1613701_2 DinB superfamily - - - 0.000000000000000000000000000001402 126.0
SHD1_k127_1613701_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000006217 67.0
SHD1_k127_1620648_0 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 515.0
SHD1_k127_1620648_1 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 510.0
SHD1_k127_1620648_2 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 431.0
SHD1_k127_1620648_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 371.0
SHD1_k127_1620648_4 - - - - 0.000000000000000000000000000001119 128.0
SHD1_k127_1620648_5 alpha/beta hydrolase fold - - - 0.00000000000000000000000002545 112.0
SHD1_k127_1626132_0 ABC transporter transmembrane region K18889 - - 1.498e-227 719.0
SHD1_k127_1626132_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 315.0
SHD1_k127_1626132_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000002377 198.0
SHD1_k127_1626132_3 PFAM response regulator receiver K02483,K07667 - - 0.00000000000001479 78.0
SHD1_k127_1626132_4 - - - - 0.000000000173 66.0
SHD1_k127_1630827_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 366.0
SHD1_k127_1630827_1 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 362.0
SHD1_k127_1630827_2 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 313.0
SHD1_k127_1632656_0 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 372.0
SHD1_k127_1632656_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 299.0
SHD1_k127_1632656_2 response to abiotic stimulus K03086,K06867 - - 0.0000000000000000000000000000000000000000000000000002269 190.0
SHD1_k127_1632656_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000003954 62.0
SHD1_k127_1648174_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 341.0
SHD1_k127_1648174_1 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000000000001255 141.0
SHD1_k127_1661489_0 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 604.0
SHD1_k127_1661489_1 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 460.0
SHD1_k127_1661489_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000001016 185.0
SHD1_k127_1661489_3 ABC-type sugar transport systems, permease components K02025 - - 0.0000000000000000000000000000004435 125.0
SHD1_k127_1662874_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 454.0
SHD1_k127_1662874_1 hydrolase activity, acting on ester bonds K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 312.0
SHD1_k127_1662874_2 DinB family - - - 0.000000000000000000000000000000000000000000000003066 179.0
SHD1_k127_1662874_3 lactoylglutathione lyase activity - - - 0.000000000000000000000000009522 109.0
SHD1_k127_1662874_4 YCII-related domain K09780 - - 0.000000000000000000000008842 104.0
SHD1_k127_1668324_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 478.0
SHD1_k127_1668324_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 432.0
SHD1_k127_1668324_2 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 415.0
SHD1_k127_1668324_3 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 332.0
SHD1_k127_1668324_4 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001228 242.0
SHD1_k127_1676824_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 431.0
SHD1_k127_1676824_1 chorismate binding enzyme K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 383.0
SHD1_k127_1676824_2 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
SHD1_k127_1676824_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000001165 134.0
SHD1_k127_1676824_4 Cupin 2, conserved barrel domain protein - - - 0.0000000005318 65.0
SHD1_k127_1684358_0 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 331.0
SHD1_k127_1693456_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 561.0
SHD1_k127_1693456_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 530.0
SHD1_k127_1693456_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000005812 200.0
SHD1_k127_1693456_3 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000005425 85.0
SHD1_k127_1693456_4 - - - - 0.0002688 44.0
SHD1_k127_1706608_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 518.0
SHD1_k127_1706608_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 338.0
SHD1_k127_1706608_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000008509 221.0
SHD1_k127_1706608_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000001398 206.0
SHD1_k127_1706608_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000002889 93.0
SHD1_k127_1717579_0 PFAM Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
SHD1_k127_1717579_1 extracellular polysaccharide biosynthetic process K16554,K21473 - - 0.000000000000004922 87.0
SHD1_k127_1728549_0 - - - - 4.646e-200 648.0
SHD1_k127_1728549_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 305.0
SHD1_k127_1728549_2 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 294.0
SHD1_k127_1728549_3 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000225 119.0
SHD1_k127_1728549_4 RF-1 domain K15034 - - 0.0000000000000000000000008546 109.0
SHD1_k127_1728549_5 - - - - 0.00000000000004092 82.0
SHD1_k127_1737979_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 1.305e-298 922.0
SHD1_k127_1737979_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 430.0
SHD1_k127_1737979_2 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000008788 165.0
SHD1_k127_1737979_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000006663 134.0
SHD1_k127_1741374_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000007286 198.0
SHD1_k127_1741374_1 methyltransferase - - - 0.0000000000000000000000000000000000000000007689 172.0
SHD1_k127_1741374_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000002647 166.0
SHD1_k127_1741374_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000004583 89.0
SHD1_k127_1759323_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1216.0
SHD1_k127_1759323_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.769e-225 709.0
SHD1_k127_1759323_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 288.0
SHD1_k127_1759323_11 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
SHD1_k127_1759323_12 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000001302 201.0
SHD1_k127_1759323_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000006324 162.0
SHD1_k127_1759323_14 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000007555 141.0
SHD1_k127_1759323_16 Protein of unknown function (DUF494) K03747 - - 0.000000000000000009525 85.0
SHD1_k127_1759323_17 - - - - 0.000000000000005421 75.0
SHD1_k127_1759323_18 Bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000405 62.0
SHD1_k127_1759323_2 Bacterial regulatory protein, Fis family - - - 1.618e-211 669.0
SHD1_k127_1759323_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 3.325e-210 662.0
SHD1_k127_1759323_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 513.0
SHD1_k127_1759323_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 496.0
SHD1_k127_1759323_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 498.0
SHD1_k127_1759323_7 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 437.0
SHD1_k127_1759323_8 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 341.0
SHD1_k127_1759323_9 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 314.0
SHD1_k127_1770039_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 523.0
SHD1_k127_1770039_1 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 311.0
SHD1_k127_1807414_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.162e-199 629.0
SHD1_k127_1807414_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 561.0
SHD1_k127_1807414_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 509.0
SHD1_k127_1807414_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 329.0
SHD1_k127_1807414_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000001668 196.0
SHD1_k127_1807414_5 - - - - 0.0000000000000000000000000001493 117.0
SHD1_k127_1807656_0 Sortilin, neurotensin receptor 3, - - - 1.331e-203 645.0
SHD1_k127_1807656_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001452 216.0
SHD1_k127_1807656_2 - - - - 0.00000000000000000000000000000000573 134.0
SHD1_k127_1834429_0 Elongation factor G C-terminus K06207 - - 5.33e-239 744.0
SHD1_k127_1834429_1 - - - - 0.00000000000000001206 89.0
SHD1_k127_1834429_2 Outer membrane protein beta-barrel domain - - - 0.000000207 60.0
SHD1_k127_1843736_0 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
SHD1_k127_1843736_1 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 384.0
SHD1_k127_1853395_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 1.998e-207 666.0
SHD1_k127_1875483_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 496.0
SHD1_k127_1875483_1 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000004703 166.0
SHD1_k127_1875483_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000009565 128.0
SHD1_k127_1885555_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000008074 179.0
SHD1_k127_1885555_1 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.0000000000000000000000000000003373 136.0
SHD1_k127_1885555_2 Glycosyl transferase family 2 K07011 - - 0.00000000000000000003897 96.0
SHD1_k127_1885555_3 Glycosyl transferase family 2 K07011 - - 0.00000000000000000006532 94.0
SHD1_k127_1885555_4 Polysaccharide biosynthesis protein - - - 0.0001282 46.0
SHD1_k127_1892519_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000006605 226.0
SHD1_k127_1892519_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000975 188.0
SHD1_k127_1904593_0 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 362.0
SHD1_k127_1904593_1 Sporulation related domain - - - 0.00000000000000000000000000000000000004936 157.0
SHD1_k127_1913416_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 391.0
SHD1_k127_1913416_1 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001982 228.0
SHD1_k127_1913416_2 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000004646 158.0
SHD1_k127_1913416_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000009957 124.0
SHD1_k127_1913416_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000000004297 104.0
SHD1_k127_1913416_5 - - - - 0.0000000000000001807 85.0
SHD1_k127_1947973_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.925e-199 631.0
SHD1_k127_1947973_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 573.0
SHD1_k127_1947973_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000004569 173.0
SHD1_k127_1947973_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000001722 70.0
SHD1_k127_195261_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 6.545e-218 693.0
SHD1_k127_195261_1 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000004388 204.0
SHD1_k127_1971621_0 peptidase K01415,K07386 - 3.4.24.71 2.506e-221 706.0
SHD1_k127_1971621_1 Carboxypeptidase regulatory-like domain - - - 4.539e-214 709.0
SHD1_k127_1971621_2 Fumarylacetoacetase N-terminal K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 570.0
SHD1_k127_1971621_3 histidine-tRNA ligase activity K01892,K02502 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000003782 218.0
SHD1_k127_1971621_4 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000001045 212.0
SHD1_k127_1971621_5 PhoQ Sensor - - - 0.000000000000000000000000000000006647 131.0
SHD1_k127_1971621_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000005189 86.0
SHD1_k127_2003139_0 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 585.0
SHD1_k127_2003139_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 335.0
SHD1_k127_2003139_2 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000002753 95.0
SHD1_k127_2009971_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 536.0
SHD1_k127_2009971_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 526.0
SHD1_k127_2009971_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 469.0
SHD1_k127_2009971_3 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000007538 78.0
SHD1_k127_203615_0 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 434.0
SHD1_k127_203615_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 342.0
SHD1_k127_203615_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007832 250.0
SHD1_k127_203615_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000006475 213.0
SHD1_k127_203615_4 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
SHD1_k127_203615_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000006869 129.0
SHD1_k127_2038073_0 tRNA synthetases class I (M) K01874 - 6.1.1.10 2.286e-232 728.0
SHD1_k127_2038073_1 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 406.0
SHD1_k127_2038073_2 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 371.0
SHD1_k127_2038073_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 331.0
SHD1_k127_2052666_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 522.0
SHD1_k127_2052666_1 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000004239 151.0
SHD1_k127_2052666_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000003507 99.0
SHD1_k127_205856_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1611.0
SHD1_k127_205856_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1072.0
SHD1_k127_205856_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1071.0
SHD1_k127_205856_3 UDP binding domain K00012 - 1.1.1.22 8.387e-196 620.0
SHD1_k127_205856_4 UDP binding domain K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 432.0
SHD1_k127_205856_5 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 322.0
SHD1_k127_205856_6 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000000000000000000000000000000000000001424 220.0
SHD1_k127_205856_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000006544 187.0
SHD1_k127_2073487_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 437.0
SHD1_k127_2073487_1 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 387.0
SHD1_k127_2073487_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 315.0
SHD1_k127_2073487_3 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001293 256.0
SHD1_k127_2073487_4 - - - - 0.000000000000000000000000000000000000000000000000000000771 209.0
SHD1_k127_2073487_5 Psort location Periplasmic, score K09807 - - 0.000000000000001594 86.0
SHD1_k127_2076091_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003297 259.0
SHD1_k127_2076091_1 Sortilin, neurotensin receptor 3, - - - 0.000000000000000004216 87.0
SHD1_k127_2078727_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 502.0
SHD1_k127_2078727_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 392.0
SHD1_k127_2078727_2 phosphatase activity K07025 - - 0.00000000000000001522 86.0
SHD1_k127_2092100_0 dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 512.0
SHD1_k127_2092100_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 496.0
SHD1_k127_2092100_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 396.0
SHD1_k127_2092100_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
SHD1_k127_2092100_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000006336 194.0
SHD1_k127_2092100_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000002283 181.0
SHD1_k127_2092100_6 - - - - 0.0000000000000000000000000000000000000001853 158.0
SHD1_k127_2092100_7 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000001476 132.0
SHD1_k127_2092100_8 - - - - 0.000000000000000000000000000003656 120.0
SHD1_k127_2092100_9 Ricin-type beta-trefoil - - - 0.000008579 58.0
SHD1_k127_2093563_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 413.0
SHD1_k127_2093563_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 376.0
SHD1_k127_2093563_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 303.0
SHD1_k127_2093563_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 303.0
SHD1_k127_2093563_4 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 287.0
SHD1_k127_2093563_5 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000004062 196.0
SHD1_k127_209357_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 601.0
SHD1_k127_209357_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 593.0
SHD1_k127_209357_2 Sodium:dicarboxylate symporter family K11103 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 516.0
SHD1_k127_209357_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000003514 216.0
SHD1_k127_209357_4 - - - - 0.0000000000000000000000000000000000000000000000001362 183.0
SHD1_k127_2098471_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.878e-286 897.0
SHD1_k127_2098471_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000003313 175.0
SHD1_k127_2098471_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000004827 130.0
SHD1_k127_2101917_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.125e-263 817.0
SHD1_k127_2101917_1 C-terminus of AA_permease K03294 - - 2.72e-208 659.0
SHD1_k127_2101917_10 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000000004317 111.0
SHD1_k127_2101917_11 - - - - 0.000000000000000000000001835 110.0
SHD1_k127_2101917_12 Methyltransferase domain - - - 0.00000000000000000000004247 108.0
SHD1_k127_2101917_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 469.0
SHD1_k127_2101917_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 426.0
SHD1_k127_2101917_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 320.0
SHD1_k127_2101917_5 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 321.0
SHD1_k127_2101917_6 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000161 164.0
SHD1_k127_2101917_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000007067 149.0
SHD1_k127_2101917_8 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000007645 139.0
SHD1_k127_2101917_9 - - - - 0.0000000000000000000000000000004152 131.0
SHD1_k127_2111580_0 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 542.0
SHD1_k127_2111580_1 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 440.0
SHD1_k127_2111580_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 423.0
SHD1_k127_2111580_3 Glycosyl hydrolase family 26 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 372.0
SHD1_k127_2111580_4 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 351.0
SHD1_k127_2111580_5 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000003232 199.0
SHD1_k127_2111580_6 Protein of unknown function (DUF4230) - - - 0.000000142 61.0
SHD1_k127_2116135_0 lysine biosynthetic process via aminoadipic acid - - - 4.335e-203 664.0
SHD1_k127_2116135_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 531.0
SHD1_k127_2116135_2 Belongs to the MenA family. Type 1 subfamily K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000005181 239.0
SHD1_k127_2116135_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000001326 205.0
SHD1_k127_2116135_4 DinB family - - - 0.000000000000000000000000000000000000000000000001409 179.0
SHD1_k127_2116135_5 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000001141 99.0
SHD1_k127_2116372_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 2.595e-236 750.0
SHD1_k127_2116372_1 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 394.0
SHD1_k127_2116372_2 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000009439 218.0
SHD1_k127_2116372_3 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000003563 140.0
SHD1_k127_2123623_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 1.235e-217 681.0
SHD1_k127_2123623_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 450.0
SHD1_k127_2123623_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 365.0
SHD1_k127_2123623_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000004469 91.0
SHD1_k127_2123690_0 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 606.0
SHD1_k127_2123690_1 stress-induced mitochondrial fusion - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 498.0
SHD1_k127_2123690_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 372.0
SHD1_k127_2123690_3 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 329.0
SHD1_k127_2123690_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 296.0
SHD1_k127_2123690_5 Cold shock K03704 - - 0.0000000000000000000000000000002968 124.0
SHD1_k127_2127844_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 414.0
SHD1_k127_2127844_1 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000002828 248.0
SHD1_k127_2127844_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000003294 115.0
SHD1_k127_2130253_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1341.0
SHD1_k127_2130253_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000004037 52.0
SHD1_k127_2133774_0 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 537.0
SHD1_k127_2133774_1 O-acyltransferase activity K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001239 270.0
SHD1_k127_2133774_2 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000000000000001338 83.0
SHD1_k127_2139129_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 499.0
SHD1_k127_2139129_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000001994 173.0
SHD1_k127_2139129_2 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000005488 159.0
SHD1_k127_2139129_3 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000002602 119.0
SHD1_k127_2140603_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1555.0
SHD1_k127_2140603_1 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000002969 146.0
SHD1_k127_2140603_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000004396 140.0
SHD1_k127_2140603_3 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000214 125.0
SHD1_k127_2144512_0 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 309.0
SHD1_k127_2144512_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000008617 195.0
SHD1_k127_2144512_2 PFAM LemA family protein K03744 - - 0.0000000000000000000000000003396 117.0
SHD1_k127_2152486_0 AcrB/AcrD/AcrF family K15726 - - 5.886e-262 820.0
SHD1_k127_2152486_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 383.0
SHD1_k127_2152486_2 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000122 215.0
SHD1_k127_2165412_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 432.0
SHD1_k127_2165412_1 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 358.0
SHD1_k127_2165412_2 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000002898 220.0
SHD1_k127_2165412_3 Helix-hairpin-helix motif K02237 - - 0.0000000000000000000000001182 113.0
SHD1_k127_2166129_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 514.0
SHD1_k127_2166129_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000001001 230.0
SHD1_k127_2166129_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000005978 178.0
SHD1_k127_2166129_3 Glycosyl transferases group 1 - - - 0.0000000000005268 71.0
SHD1_k127_2180049_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 7.596e-290 904.0
SHD1_k127_2180049_1 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 441.0
SHD1_k127_2183498_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 8.217e-219 687.0
SHD1_k127_2183498_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 517.0
SHD1_k127_2183498_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005529 252.0
SHD1_k127_2183498_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000004288 235.0
SHD1_k127_2183498_4 - - - - 0.00000000000000000000000000000000000000000000000000000009499 211.0
SHD1_k127_2183498_5 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000002639 133.0
SHD1_k127_2183498_6 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000006408 114.0
SHD1_k127_2183498_7 Competence protein K02238 - - 0.0000000000000002752 85.0
SHD1_k127_2209599_0 COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 514.0
SHD1_k127_2211793_0 PFAM Enoyl-CoA hydratase isomerase - - - 1.198e-224 717.0
SHD1_k127_2211793_1 COG0840 Methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000004248 198.0
SHD1_k127_2228295_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1068.0
SHD1_k127_2228295_1 Hsp70 protein K03569 - - 2.193e-200 626.0
SHD1_k127_2228295_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 609.0
SHD1_k127_2228295_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 570.0
SHD1_k127_2228295_4 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007643 274.0
SHD1_k127_2228295_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000002425 206.0
SHD1_k127_2228295_6 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000003202 204.0
SHD1_k127_2228295_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000001785 137.0
SHD1_k127_2228295_8 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000005396 57.0
SHD1_k127_2228547_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 3.448e-258 811.0
SHD1_k127_2228547_1 CarboxypepD_reg-like domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 557.0
SHD1_k127_2228547_2 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 426.0
SHD1_k127_2228547_3 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 341.0
SHD1_k127_2228547_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007774 282.0
SHD1_k127_2228547_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005141 274.0
SHD1_k127_2248497_0 Outer membrane protein beta-barrel family - - - 0.0 1026.0
SHD1_k127_2248497_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000005468 243.0
SHD1_k127_2260823_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 402.0
SHD1_k127_2260823_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 273.0
SHD1_k127_2260823_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000005264 220.0
SHD1_k127_2260823_3 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000002547 149.0
SHD1_k127_2260823_4 PFAM acylphosphatase K01512 - 3.6.1.7 0.0000000000000008836 79.0
SHD1_k127_2260823_5 Glycosyltransferase like family 2 - - - 0.000000000000005406 80.0
SHD1_k127_2264074_0 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 9.544e-211 671.0
SHD1_k127_2264074_1 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001073 224.0
SHD1_k127_2264074_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000003661 196.0
SHD1_k127_2264074_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000006841 178.0
SHD1_k127_2264074_4 - - - - 0.00000000000000000000000000000000000001407 153.0
SHD1_k127_2264074_5 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000006364 130.0
SHD1_k127_2264074_6 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.00000002362 63.0
SHD1_k127_2264074_7 Receptor - - - 0.000001509 54.0
SHD1_k127_2275036_0 Sortilin, neurotensin receptor 3, - - - 5.628e-238 763.0
SHD1_k127_2277821_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 525.0
SHD1_k127_2277821_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 481.0
SHD1_k127_2277821_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 382.0
SHD1_k127_2277821_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 315.0
SHD1_k127_2277821_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 301.0
SHD1_k127_2277821_5 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000003422 187.0
SHD1_k127_2277821_6 Thiamine monophosphate synthase K00788,K10810 - 2.5.1.3,5.3.99.10 0.00000000000000000000000000008493 125.0
SHD1_k127_2277821_7 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000002145 104.0
SHD1_k127_2277821_8 Bifunctional sulfur carrier protein thiazole synthase K03154 - - 0.0000000000005482 72.0
SHD1_k127_2287619_0 PFAM ABC transporter related K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 445.0
SHD1_k127_2287619_1 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 382.0
SHD1_k127_2287619_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000001355 143.0
SHD1_k127_2287619_3 O-methyltransferase activity - - - 0.000000000000000008715 92.0
SHD1_k127_2312993_0 lysine biosynthetic process via aminoadipic acid - - - 3.439e-295 932.0
SHD1_k127_2312993_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 504.0
SHD1_k127_2312993_2 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
SHD1_k127_2312993_3 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000000001005 232.0
SHD1_k127_2318735_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1059.0
SHD1_k127_2318735_1 4Fe-4S binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 379.0
SHD1_k127_2318735_2 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 379.0
SHD1_k127_2318735_3 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000057 108.0
SHD1_k127_2318920_0 ABC transporter transmembrane region K18890 - - 2.434e-230 729.0
SHD1_k127_2318920_1 Transglycosylase associated protein - - - 0.00000000000001749 75.0
SHD1_k127_2321862_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.773e-255 800.0
SHD1_k127_2321862_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 591.0
SHD1_k127_2321862_10 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000001619 118.0
SHD1_k127_2321862_11 FecCD transport family K02015 - - 0.0000000000000000000000001871 109.0
SHD1_k127_2321862_12 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000002719 80.0
SHD1_k127_2321862_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 424.0
SHD1_k127_2321862_3 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 308.0
SHD1_k127_2321862_4 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 287.0
SHD1_k127_2321862_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005963 255.0
SHD1_k127_2321862_6 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000000000000000000000000000000000000000000004494 216.0
SHD1_k127_2321862_7 PTS system sorbose subfamily IIB component K19507 - - 0.00000000000000000000000000000000000000000000000000000000004709 209.0
SHD1_k127_2321862_8 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000002089 124.0
SHD1_k127_2321862_9 PTS system fructose IIA component K02744 - - 0.0000000000000000000000000001387 120.0
SHD1_k127_2330930_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1043.0
SHD1_k127_2330930_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 481.0
SHD1_k127_2330930_2 asparaginase activity K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 423.0
SHD1_k127_2330930_3 transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004097 253.0
SHD1_k127_2330930_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
SHD1_k127_2330930_5 - - - - 0.000009275 52.0
SHD1_k127_233802_0 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 416.0
SHD1_k127_233802_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 413.0
SHD1_k127_233802_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 413.0
SHD1_k127_233802_3 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000003521 188.0
SHD1_k127_233802_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000001257 148.0
SHD1_k127_2351117_0 Sugar (and other) transporter K07058 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 4.952e-237 751.0
SHD1_k127_2351117_1 Aminotransferase class-V - - - 6.766e-198 624.0
SHD1_k127_2351117_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000002994 120.0
SHD1_k127_2351117_3 Transmembrane secretion effector - - - 0.000000000000000000000000005716 115.0
SHD1_k127_2352789_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 6.96e-231 723.0
SHD1_k127_2352789_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 420.0
SHD1_k127_2352789_2 sirohydrochlorin cobaltochelatase activity K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.000000000000000000000000000000001439 136.0
SHD1_k127_2356407_0 Elongation factor G, domain IV K02355 - - 0.0 1024.0
SHD1_k127_2356407_1 - - - - 0.0000000000000000000000000000000000000000000006277 172.0
SHD1_k127_2356407_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000002892 139.0
SHD1_k127_2356407_3 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000001725 102.0
SHD1_k127_2356407_4 Phosphoglycerate mutase family - - - 0.000000000000004839 80.0
SHD1_k127_2356407_5 protein kinase activity K12132 - 2.7.11.1 0.00000000008636 72.0
SHD1_k127_2356407_6 Putative prokaryotic signal transducing protein - - - 0.00000002172 63.0
SHD1_k127_2360231_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 595.0
SHD1_k127_2360231_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 560.0
SHD1_k127_2360231_2 PFAM Beta-lactamase K18988 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 415.0
SHD1_k127_2362552_0 cellulose binding - - - 9.957e-304 945.0
SHD1_k127_2362552_1 Protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000000001043 190.0
SHD1_k127_2362552_2 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000008565 177.0
SHD1_k127_2362552_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000001872 162.0
SHD1_k127_2362552_4 DinB family - - - 0.00000000000000000000000000000000000001537 149.0
SHD1_k127_2362552_5 Protein of unknown function (DUF1569) - - - 0.00000000000000000000000000007225 120.0
SHD1_k127_2362552_6 impB/mucB/samB family - - - 0.0000000002206 73.0
SHD1_k127_2362552_7 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.00001533 55.0
SHD1_k127_2370897_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.977e-286 882.0
SHD1_k127_2370897_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001667 233.0
SHD1_k127_2370897_2 YjbR - - - 0.00000000000001423 75.0
SHD1_k127_237813_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 7.635e-288 896.0
SHD1_k127_237813_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 317.0
SHD1_k127_237813_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000002698 209.0
SHD1_k127_237813_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000002003 61.0
SHD1_k127_2383228_0 MMPL family K03296 - - 0.0 1122.0
SHD1_k127_2383228_1 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 320.0
SHD1_k127_2383228_2 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 302.0
SHD1_k127_2383228_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002713 295.0
SHD1_k127_2383228_4 ATPase activity - - - 0.0000000002904 67.0
SHD1_k127_2391286_0 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 468.0
SHD1_k127_2391286_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003698 269.0
SHD1_k127_2391286_2 Acetyltransferase (GNAT) domain K02348 - - 0.00000000000000000009783 91.0
SHD1_k127_2392828_0 Sortilin, neurotensin receptor 3, - - - 0.0 1455.0
SHD1_k127_2392828_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 346.0
SHD1_k127_2392828_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
SHD1_k127_2392828_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000001956 205.0
SHD1_k127_2392828_4 PFAM band 7 protein - - - 0.00000000000000000000746 94.0
SHD1_k127_2392828_6 - - - - 0.000001185 58.0
SHD1_k127_2395458_0 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 356.0
SHD1_k127_2395458_1 Leishmanolysin - - - 0.0000000000000000000000000000000000000000000000000000000000000004276 239.0
SHD1_k127_2395458_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000002217 230.0
SHD1_k127_2395458_3 FtsX-like permease family K02004 - - 0.00001483 47.0
SHD1_k127_2396822_0 Starch-binding associating with outer membrane - - - 5.999e-219 687.0
SHD1_k127_2396822_1 TonB-linked outer membrane protein, SusC RagA family - - - 0.0000000000000000000000000000000000000000001861 159.0
SHD1_k127_2399535_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1024.0
SHD1_k127_2399535_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 346.0
SHD1_k127_2399535_2 Sporulation related domain - - - 0.000000000000000000000000000000000000000000002635 179.0
SHD1_k127_2399535_3 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000002657 162.0
SHD1_k127_2399535_4 - - - - 0.0000000000000000000000002831 112.0
SHD1_k127_241867_0 protein histidine kinase activity - - - 0.0 1019.0
SHD1_k127_241867_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 588.0
SHD1_k127_241867_10 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000003262 200.0
SHD1_k127_241867_11 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000000001036 199.0
SHD1_k127_241867_12 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000001232 194.0
SHD1_k127_241867_13 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000001122 184.0
SHD1_k127_241867_14 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000004916 151.0
SHD1_k127_241867_15 Methylamine utilisation protein MauE - - - 0.00000001257 65.0
SHD1_k127_241867_16 Cupin 2, conserved barrel domain protein - - - 0.0000002755 59.0
SHD1_k127_241867_17 PLD-like domain - - - 0.0000003307 54.0
SHD1_k127_241867_18 cheY-homologous receiver domain K20977 - - 0.00000374 53.0
SHD1_k127_241867_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 357.0
SHD1_k127_241867_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 343.0
SHD1_k127_241867_4 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 352.0
SHD1_k127_241867_5 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 314.0
SHD1_k127_241867_6 Pirin C-terminal cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 295.0
SHD1_k127_241867_7 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000023 312.0
SHD1_k127_241867_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000045 258.0
SHD1_k127_241867_9 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008006 264.0
SHD1_k127_2421926_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.994e-295 911.0
SHD1_k127_2421926_1 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 407.0
SHD1_k127_2421926_2 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 390.0
SHD1_k127_2421926_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 339.0
SHD1_k127_2421926_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
SHD1_k127_2421926_6 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000002565 196.0
SHD1_k127_2421926_7 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000000000000000000000000001105 161.0
SHD1_k127_2445650_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000377 171.0
SHD1_k127_2445650_2 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 0.00000000000000000000001805 104.0
SHD1_k127_245593_0 TonB-dependent receptor K02014 - - 6.487e-252 803.0
SHD1_k127_245593_1 Peptidase family M13 K07386 - - 1.726e-247 781.0
SHD1_k127_245593_2 Domain of unknown function (DUF5117) - - - 6.534e-211 666.0
SHD1_k127_245593_3 PFAM ATP dependent DNA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 454.0
SHD1_k127_245593_4 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 331.0
SHD1_k127_245593_5 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000001196 207.0
SHD1_k127_245593_6 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000003112 171.0
SHD1_k127_245593_7 Cold shock protein domain K03704 - - 0.000000000000000000000000000000001096 134.0
SHD1_k127_245593_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000122 121.0
SHD1_k127_2457151_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 400.0
SHD1_k127_2457151_1 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
SHD1_k127_2457151_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000004683 245.0
SHD1_k127_2457151_3 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
SHD1_k127_2457151_4 - - - - 0.0000004291 56.0
SHD1_k127_2463808_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 481.0
SHD1_k127_2463808_1 secondary active sulfate transmembrane transporter activity K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 440.0
SHD1_k127_2463808_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 370.0
SHD1_k127_2463808_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004292 278.0
SHD1_k127_2463808_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
SHD1_k127_2463808_5 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000004986 153.0
SHD1_k127_2483496_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 622.0
SHD1_k127_2484596_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 9.1e-205 647.0
SHD1_k127_2484596_1 4Fe-4S binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 567.0
SHD1_k127_2484596_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 473.0
SHD1_k127_2484596_3 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 305.0
SHD1_k127_2484596_4 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004231 287.0
SHD1_k127_2484596_5 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000326 226.0
SHD1_k127_2485801_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009871 245.0
SHD1_k127_2485801_1 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000001273 140.0
SHD1_k127_2485801_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000001832 136.0
SHD1_k127_2485801_3 ECF sigma factor K03088 - - 0.000000000000000000000000000000002469 136.0
SHD1_k127_2485801_4 - - - - 0.000000109 57.0
SHD1_k127_2497757_0 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 573.0
SHD1_k127_2497757_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000549 251.0
SHD1_k127_2505431_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 603.0
SHD1_k127_2505431_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 409.0
SHD1_k127_2505431_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000004446 122.0
SHD1_k127_2505431_3 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000004606 97.0
SHD1_k127_2505431_4 - - - - 0.000000000000000000003264 104.0
SHD1_k127_252234_0 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 380.0
SHD1_k127_252234_1 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 329.0
SHD1_k127_252234_2 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001206 231.0
SHD1_k127_252234_3 - - - - 0.0000002132 59.0
SHD1_k127_2528801_0 dehydrogenase, E1 component K11381 - 1.2.4.4 2.482e-293 913.0
SHD1_k127_2528801_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 474.0
SHD1_k127_2528801_2 COG1024 Enoyl-CoA hydratase carnithine racemase K15866 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 0.0000001319 53.0
SHD1_k127_2541135_0 curli production assembly transport component CsgG K04087 - - 0.000000000000000000002794 105.0
SHD1_k127_2541135_1 Esterase PHB depolymerase - - - 0.0001017 54.0
SHD1_k127_2543834_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1099.0
SHD1_k127_2547218_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1015.0
SHD1_k127_2547218_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 429.0
SHD1_k127_2547218_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
SHD1_k127_2547218_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000005011 151.0
SHD1_k127_2547218_4 - - - - 0.000000000000000000000000009486 111.0
SHD1_k127_2552403_0 AMIN domain K02666 - - 2.986e-208 665.0
SHD1_k127_2552403_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 558.0
SHD1_k127_2558307_0 secondary active sulfate transmembrane transporter activity - - - 6.516e-282 885.0
SHD1_k127_2558307_1 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
SHD1_k127_2558307_2 permease - - - 0.000000000000000000000000000000000000001192 151.0
SHD1_k127_2580900_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 559.0
SHD1_k127_2580900_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 464.0
SHD1_k127_2580900_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 405.0
SHD1_k127_2580900_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 267.0
SHD1_k127_2580900_4 Glycosyl transferase family 2 K08301 - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
SHD1_k127_2580900_5 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.0000000000000000000000000000000000000000003793 171.0
SHD1_k127_2580900_6 - - - - 0.000000006119 60.0
SHD1_k127_2591080_0 FtsX-like permease family K02004 - - 2.791e-225 722.0
SHD1_k127_2591080_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 451.0
SHD1_k127_2591080_10 COGs COG2823 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
SHD1_k127_2591080_11 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000005422 155.0
SHD1_k127_2591080_12 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000002371 145.0
SHD1_k127_2591080_13 Ppx/GppA phosphatase family - - - 0.0000000000000000000000000001144 125.0
SHD1_k127_2591080_14 Yip1 domain - - - 0.0000000000000000000000000248 118.0
SHD1_k127_2591080_15 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000007031 118.0
SHD1_k127_2591080_16 AMP binding - - - 0.0000000000001653 81.0
SHD1_k127_2591080_17 BON domain - - - 0.00000000223 68.0
SHD1_k127_2591080_18 Belongs to the universal stress protein A family - - - 0.0000001667 63.0
SHD1_k127_2591080_19 Belongs to the universal stress protein A family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0006466 48.0
SHD1_k127_2591080_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 367.0
SHD1_k127_2591080_3 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 368.0
SHD1_k127_2591080_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 341.0
SHD1_k127_2591080_5 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 336.0
SHD1_k127_2591080_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 308.0
SHD1_k127_2591080_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005868 278.0
SHD1_k127_2591080_8 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003995 268.0
SHD1_k127_2591080_9 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000007138 211.0
SHD1_k127_2596633_0 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 414.0
SHD1_k127_2596633_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 369.0
SHD1_k127_2596633_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 315.0
SHD1_k127_2596633_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000007941 176.0
SHD1_k127_2596633_4 - - - - 0.0000000000000000000000000000000000003221 158.0
SHD1_k127_2596633_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000002195 108.0
SHD1_k127_2600380_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 1.449e-198 627.0
SHD1_k127_2600380_1 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 396.0
SHD1_k127_2600380_2 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000003461 175.0
SHD1_k127_2600380_3 - - - - 0.00000000000000000000000000000000000008396 147.0
SHD1_k127_2600380_4 - - - - 0.0000000000000000000000000000000000007567 149.0
SHD1_k127_2601034_0 Polysaccharide biosynthesis/export protein - - - 9.25e-234 742.0
SHD1_k127_2601034_1 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000112 194.0
SHD1_k127_2601034_2 Capsule assembly protein Wzi - - - 0.0000000000000000001933 102.0
SHD1_k127_2607816_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 331.0
SHD1_k127_2607816_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000004496 167.0
SHD1_k127_2632705_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1028.0
SHD1_k127_2632705_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.753e-269 849.0
SHD1_k127_2632705_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 507.0
SHD1_k127_2632705_3 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 462.0
SHD1_k127_2632705_4 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000001312 202.0
SHD1_k127_2632705_5 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000003816 198.0
SHD1_k127_2632705_6 Selenoprotein, putative - - - 0.00000000000005675 74.0
SHD1_k127_2639330_0 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 361.0
SHD1_k127_2639330_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 326.0
SHD1_k127_2639330_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 300.0
SHD1_k127_2639330_3 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002345 246.0
SHD1_k127_2639330_4 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000004602 106.0
SHD1_k127_2639330_5 Belongs to the UPF0754 family - - - 0.000001796 54.0
SHD1_k127_2655642_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.389e-210 668.0
SHD1_k127_2655642_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 372.0
SHD1_k127_2655642_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 343.0
SHD1_k127_2655642_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000007773 153.0
SHD1_k127_2671340_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 3.714e-266 851.0
SHD1_k127_2671340_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 475.0
SHD1_k127_2671340_2 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 328.0
SHD1_k127_2671340_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001202 275.0
SHD1_k127_2671340_4 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000007338 203.0
SHD1_k127_2671340_5 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000004092 158.0
SHD1_k127_2671340_6 OmpA family K03640 - - 0.0000000000000000000000000004815 123.0
SHD1_k127_2673892_0 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 542.0
SHD1_k127_2673892_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006749 250.0
SHD1_k127_2673892_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000009208 216.0
SHD1_k127_2673892_3 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000008286 176.0
SHD1_k127_2673892_4 - - - - 0.000000000000000000000002078 115.0
SHD1_k127_2673892_5 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000000000000009056 87.0
SHD1_k127_2673892_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000006867 85.0
SHD1_k127_2673892_7 - - - - 0.0003987 44.0
SHD1_k127_2676023_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 451.0
SHD1_k127_2676023_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 426.0
SHD1_k127_2676023_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 419.0
SHD1_k127_2676023_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 366.0
SHD1_k127_2676023_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004491 287.0
SHD1_k127_2676023_5 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000517 229.0
SHD1_k127_2685600_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.679e-232 730.0
SHD1_k127_2685600_1 Peptidase family M49 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 313.0
SHD1_k127_2719521_0 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 467.0
SHD1_k127_2719521_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 460.0
SHD1_k127_2719521_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 294.0
SHD1_k127_2719521_3 Cytidylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002527 235.0
SHD1_k127_2719521_4 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000008172 221.0
SHD1_k127_2719521_5 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000002583 177.0
SHD1_k127_2719521_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000002117 153.0
SHD1_k127_2747553_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.175e-194 612.0
SHD1_k127_2747553_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 546.0
SHD1_k127_2747553_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 380.0
SHD1_k127_2747553_3 PFAM metal-dependent phosphohydrolase, HD sub domain K02030,K06950,K07814,K09749,K16923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 272.0
SHD1_k127_2747553_4 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000155 190.0
SHD1_k127_2747553_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000001188 186.0
SHD1_k127_2747553_6 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000009386 161.0
SHD1_k127_2747553_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000003529 151.0
SHD1_k127_2753821_0 ABC transporter K06158 - - 5.211e-194 622.0
SHD1_k127_2753821_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 531.0
SHD1_k127_2753821_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 414.0
SHD1_k127_2753821_3 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000004655 217.0
SHD1_k127_2753821_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000002761 117.0
SHD1_k127_2754229_0 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 519.0
SHD1_k127_2761651_0 Belongs to the allantoicase family K01477 GO:0003674,GO:0003824,GO:0004037,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 507.0
SHD1_k127_2761651_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 310.0
SHD1_k127_2761651_2 allantoin biosynthetic process K01477,K16840 - 3.5.3.4,4.1.1.97 0.00000000000000000000000252 109.0
SHD1_k127_2762394_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 468.0
SHD1_k127_2762394_1 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
SHD1_k127_2762394_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
SHD1_k127_2762394_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000002349 177.0
SHD1_k127_2769218_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 477.0
SHD1_k127_2769218_1 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000543 261.0
SHD1_k127_2769218_2 - - - - 0.0000001777 56.0
SHD1_k127_2778457_0 Sigma-54 interaction domain K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000002711 205.0
SHD1_k127_2778457_1 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000006623 135.0
SHD1_k127_2778457_2 Major facilitator Superfamily - - - 0.0002962 43.0
SHD1_k127_2783434_0 Involved in the tonB-independent uptake of proteins - - - 6.488e-237 747.0
SHD1_k127_2783434_1 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000000000001887 227.0
SHD1_k127_2783434_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001586 226.0
SHD1_k127_2783434_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000002404 171.0
SHD1_k127_2783434_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000009233 160.0
SHD1_k127_2783434_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000023 115.0
SHD1_k127_2785234_0 Amidohydrolase family K06015 - 3.5.1.81 8.976e-245 767.0
SHD1_k127_2785234_1 Glycine betaine K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 358.0
SHD1_k127_2785234_2 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 322.0
SHD1_k127_2785234_3 abc transporter atp-binding protein K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.0000000000000000000000000000000000000000000000001344 182.0
SHD1_k127_2785234_4 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000129 153.0
SHD1_k127_2800201_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 486.0
SHD1_k127_2800201_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 359.0
SHD1_k127_2800201_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 330.0
SHD1_k127_2800201_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004776 245.0
SHD1_k127_2814729_0 Amidohydrolase family - - - 3.284e-230 722.0
SHD1_k127_2814729_1 response to antibiotic K00573 - 2.1.1.77 9.467e-194 614.0
SHD1_k127_2814729_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002188 237.0
SHD1_k127_2814729_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000005925 93.0
SHD1_k127_2814729_4 Protein of unknown function (DUF455) - - - 0.000004141 57.0
SHD1_k127_2814729_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K03921 - 1.14.19.11,1.14.19.2,1.14.19.26,1.16.3.1 0.0000178 55.0
SHD1_k127_2821293_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
SHD1_k127_2821293_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 384.0
SHD1_k127_2821293_2 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 327.0
SHD1_k127_2821293_3 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
SHD1_k127_2821293_4 - - - - 0.00000000000000000000000000000000000000000000000000004925 198.0
SHD1_k127_2821293_5 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000003646 139.0
SHD1_k127_2823159_0 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 370.0
SHD1_k127_2823159_1 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.000000000000000005225 90.0
SHD1_k127_2823159_2 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000925 87.0
SHD1_k127_282588_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 1.496e-211 666.0
SHD1_k127_282588_1 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 430.0
SHD1_k127_282588_2 serine-type endopeptidase activity - - - 0.0000000000001284 72.0
SHD1_k127_2847426_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 533.0
SHD1_k127_2847426_1 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 404.0
SHD1_k127_2847426_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000001543 61.0
SHD1_k127_2848705_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 614.0
SHD1_k127_2848705_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 341.0
SHD1_k127_2848705_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000002503 123.0
SHD1_k127_2852719_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 362.0
SHD1_k127_2852719_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007982 238.0
SHD1_k127_2852719_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004632 233.0
SHD1_k127_2852719_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000002799 202.0
SHD1_k127_2853876_0 Putative glucoamylase K13688 - - 3.96e-252 797.0
SHD1_k127_2853876_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.631e-214 673.0
SHD1_k127_2858907_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 489.0
SHD1_k127_2858907_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 440.0
SHD1_k127_2858907_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 301.0
SHD1_k127_2858907_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000006089 270.0
SHD1_k127_2858907_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000004689 241.0
SHD1_k127_2858907_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
SHD1_k127_2858907_6 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000001145 140.0
SHD1_k127_2858907_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000032 139.0
SHD1_k127_2858907_8 - - - - 0.0000000000001197 79.0
SHD1_k127_2859375_0 Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 597.0
SHD1_k127_2859375_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 526.0
SHD1_k127_2859375_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 312.0
SHD1_k127_2859375_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007191 274.0
SHD1_k127_2859375_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
SHD1_k127_2859375_5 PglZ domain - - - 0.00000000000000000000000005832 108.0
SHD1_k127_2859375_6 - - - - 0.0000000000000001524 84.0
SHD1_k127_2861208_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 309.0
SHD1_k127_2861208_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000001541 213.0
SHD1_k127_2861208_2 amino acid - - - 0.00000000000000000000000000000000000000000001433 173.0
SHD1_k127_286470_0 TonB-dependent receptor - - - 3.142e-252 817.0
SHD1_k127_286470_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 477.0
SHD1_k127_286470_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 308.0
SHD1_k127_286470_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000001297 117.0
SHD1_k127_286470_4 Gram-negative bacterial TonB protein C-terminal - - - 0.00000003593 61.0
SHD1_k127_2869221_0 Belongs to the carbamoyltransferase HypF family K04656 - - 5.213e-205 662.0
SHD1_k127_2869221_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 396.0
SHD1_k127_2869221_2 Cardiolipin synthetase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 347.0
SHD1_k127_2869221_3 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 258.0
SHD1_k127_2869221_4 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000003917 215.0
SHD1_k127_2869221_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00005495 48.0
SHD1_k127_2875568_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.617e-199 629.0
SHD1_k127_2875568_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000005422 240.0
SHD1_k127_2875568_2 - - - - 0.00000000004425 67.0
SHD1_k127_2877646_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 554.0
SHD1_k127_2877646_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 374.0
SHD1_k127_2877646_2 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 302.0
SHD1_k127_2877646_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000001235 220.0
SHD1_k127_2877646_4 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000000000000000000004654 155.0
SHD1_k127_2877646_5 Rossmann-like domain - - - 0.000000000000000000000000000003323 132.0
SHD1_k127_2891260_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 565.0
SHD1_k127_2891260_1 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 452.0
SHD1_k127_2891260_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 444.0
SHD1_k127_2891260_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 340.0
SHD1_k127_2891260_4 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000005673 229.0
SHD1_k127_2891260_5 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000002395 210.0
SHD1_k127_2891260_6 ABC transporter K02065 - - 0.00000004457 54.0
SHD1_k127_2891260_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000004436 49.0
SHD1_k127_2893236_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 428.0
SHD1_k127_2893236_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 396.0
SHD1_k127_2893236_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000002136 157.0
SHD1_k127_2893236_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000004994 79.0
SHD1_k127_2893814_0 Leishmanolysin - - - 0.00000000000000000000000000000000000000000000000000000000139 217.0
SHD1_k127_2894374_0 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 519.0
SHD1_k127_2894374_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 455.0
SHD1_k127_2894374_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 403.0
SHD1_k127_2894374_3 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000003529 207.0
SHD1_k127_2894374_4 protease with the C-terminal PDZ domain - - - 0.00002591 50.0
SHD1_k127_2900593_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000009869 135.0
SHD1_k127_2900593_1 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000001764 136.0
SHD1_k127_2902451_0 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 499.0
SHD1_k127_2902451_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
SHD1_k127_2902451_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 289.0
SHD1_k127_2902451_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000009204 191.0
SHD1_k127_2902451_4 glyoxalase III activity - - - 0.00000000000000000000000000000000000000009344 156.0
SHD1_k127_2902451_5 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000000002664 142.0
SHD1_k127_2902451_6 Acetyltransferase (GNAT) domain K02348 - - 0.00000000000000000000000000000000000836 139.0
SHD1_k127_2902451_8 - - - - 0.000000000001037 72.0
SHD1_k127_2902451_9 DinB superfamily - - - 0.000000000001429 75.0
SHD1_k127_2917634_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.056e-226 715.0
SHD1_k127_2917634_1 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 589.0
SHD1_k127_2917634_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 502.0
SHD1_k127_2917634_3 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005307 279.0
SHD1_k127_2917634_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000671 240.0
SHD1_k127_2917634_5 DinB family - - - 0.0000000000000000000000000000000000000000000000000000003126 200.0
SHD1_k127_2917634_6 - - - - 0.000000000000000000000000000000000005943 143.0
SHD1_k127_2917634_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000001441 108.0
SHD1_k127_2926965_0 Bacterial regulatory protein, Fis family - - - 1.155e-213 672.0
SHD1_k127_2926965_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 633.0
SHD1_k127_2926965_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 483.0
SHD1_k127_2926965_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
SHD1_k127_2926965_4 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 329.0
SHD1_k127_2926965_5 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000006805 238.0
SHD1_k127_2926965_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002569 218.0
SHD1_k127_2926965_7 - - - - 0.00000000000000000000000000000000000000000000000001081 188.0
SHD1_k127_2926965_8 OmpA family K03640 - - 0.00000000000000000000003152 100.0
SHD1_k127_2926965_9 - - - - 0.00000000005841 75.0
SHD1_k127_293742_0 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00467,K10530 - 1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 314.0
SHD1_k127_293742_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
SHD1_k127_293742_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000006251 130.0
SHD1_k127_2968420_0 AMP-binding enzyme C-terminal domain K01907 - 6.2.1.16 7.819e-233 735.0
SHD1_k127_2968420_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 1.409e-224 699.0
SHD1_k127_2968420_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 574.0
SHD1_k127_2968420_3 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 374.0
SHD1_k127_2968420_4 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 345.0
SHD1_k127_2968420_5 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
SHD1_k127_2968420_6 Acetyl-coenzyme A synthetase N-terminus - - - 0.0000000000000000000000000000000001803 133.0
SHD1_k127_2968420_7 - - - - 0.0000000000003813 75.0
SHD1_k127_2971606_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2253.0
SHD1_k127_2971606_1 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 1.058e-217 684.0
SHD1_k127_2971606_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 414.0
SHD1_k127_2971606_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 379.0
SHD1_k127_2971606_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003915 286.0
SHD1_k127_2971606_5 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001999 252.0
SHD1_k127_2971606_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000001263 211.0
SHD1_k127_2971606_7 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000002399 206.0
SHD1_k127_2971606_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000002789 138.0
SHD1_k127_2971606_9 Membrane - - - 0.000000000000000000000000000004198 137.0
SHD1_k127_2973104_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.923e-235 734.0
SHD1_k127_2973104_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 359.0
SHD1_k127_2973104_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 336.0
SHD1_k127_2975090_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 571.0
SHD1_k127_2975090_1 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 500.0
SHD1_k127_2975090_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 498.0
SHD1_k127_2975090_3 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000003803 242.0
SHD1_k127_2975090_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001592 241.0
SHD1_k127_2975090_5 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000004346 176.0
SHD1_k127_2975090_6 DinB family - - - 0.0000000000000000000000000000000005856 136.0
SHD1_k127_2975090_7 PFAM DsrC family protein K11179 - - 0.000000000000000000000000000000001491 135.0
SHD1_k127_2975090_8 protein kinase activity - - - 0.0006911 42.0
SHD1_k127_2975903_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 495.0
SHD1_k127_2975903_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 386.0
SHD1_k127_2977326_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 413.0
SHD1_k127_2977326_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
SHD1_k127_2977326_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000263 280.0
SHD1_k127_2977326_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000002011 176.0
SHD1_k127_2977326_4 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00003019 51.0
SHD1_k127_2983905_0 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 534.0
SHD1_k127_2983905_1 Belongs to the HpcH HpaI aldolase family K18292 - 4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 494.0
SHD1_k127_2983905_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 322.0
SHD1_k127_2983905_3 tRNA wobble adenosine to inosine editing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006133 261.0
SHD1_k127_2983905_4 Peptidase family M28 - - - 0.000000000000000000000000000000000005541 145.0
SHD1_k127_2983905_5 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000003336 123.0
SHD1_k127_2983905_6 allantoin biosynthetic process K01477,K16840 - 3.5.3.4,4.1.1.97 0.00000000000000000002426 93.0
SHD1_k127_2985748_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 486.0
SHD1_k127_2985748_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 396.0
SHD1_k127_2985748_2 - - - - 0.0000000000006439 77.0
SHD1_k127_3007633_0 Repeat of Unknown Function (DUF347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 310.0
SHD1_k127_3007633_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 299.0
SHD1_k127_3007633_2 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.000000000000000000000000000000000000000000000000000000000000000002598 251.0
SHD1_k127_3007633_3 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000003012 166.0
SHD1_k127_3007633_4 - - - - 0.00000000000000000000663 98.0
SHD1_k127_301145_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 595.0
SHD1_k127_301145_1 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 438.0
SHD1_k127_301145_2 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000258 213.0
SHD1_k127_301145_3 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000116 179.0
SHD1_k127_301145_4 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.0000000000000000000000000000000000001183 150.0
SHD1_k127_301145_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000002333 140.0
SHD1_k127_3012239_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002989 260.0
SHD1_k127_3012239_1 CoA binding domain K06929 - - 0.000000000000001354 77.0
SHD1_k127_3012239_2 - - - - 0.0000001736 60.0
SHD1_k127_3012239_3 domain, Protein - - - 0.00003184 54.0
SHD1_k127_3012239_4 - - - - 0.0002362 49.0
SHD1_k127_3012810_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 446.0
SHD1_k127_3012810_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 363.0
SHD1_k127_3012810_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000007789 115.0
SHD1_k127_3015619_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 631.0
SHD1_k127_3015619_1 Domain of unknown function (DUF4974) K07165 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009004 267.0
SHD1_k127_3015619_2 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
SHD1_k127_3015619_3 - - - - 0.0000000000000000000000000000000000000000000000000004517 196.0
SHD1_k127_3015619_5 - - - - 0.00000005856 57.0
SHD1_k127_3018759_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 541.0
SHD1_k127_3018759_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 540.0
SHD1_k127_3018759_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 540.0
SHD1_k127_3018759_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 414.0
SHD1_k127_3024259_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 487.0
SHD1_k127_3024259_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 393.0
SHD1_k127_3024259_2 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000001365 189.0
SHD1_k127_3024259_3 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000209 190.0
SHD1_k127_3024259_4 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000949 186.0
SHD1_k127_3024259_5 peptidase K01415,K07386 - 3.4.24.71 0.0000000001056 62.0
SHD1_k127_302535_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 323.0
SHD1_k127_302535_1 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 292.0
SHD1_k127_302535_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001055 189.0
SHD1_k127_302535_3 - - - - 0.0000000001112 64.0
SHD1_k127_3035735_0 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 448.0
SHD1_k127_3035735_1 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000003138 153.0
SHD1_k127_3035735_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000005947 74.0
SHD1_k127_3054155_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 1.074e-202 637.0
SHD1_k127_3054155_1 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 386.0
SHD1_k127_3054155_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 395.0
SHD1_k127_3054155_3 Protein conserved in bacteria K01446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 371.0
SHD1_k127_3054155_4 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006165 243.0
SHD1_k127_3054155_5 Catalase K03781 - 1.11.1.6 0.000000000000000000000000000000006137 132.0
SHD1_k127_3074549_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000009609 168.0
SHD1_k127_3074549_1 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000001041 138.0
SHD1_k127_3074549_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000004533 126.0
SHD1_k127_3074549_3 Phospholipid methyltransferase - - - 0.00000000000000001518 83.0
SHD1_k127_3075409_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 410.0
SHD1_k127_3075409_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 279.0
SHD1_k127_3075409_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003987 274.0
SHD1_k127_3075409_3 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000005057 199.0
SHD1_k127_3075409_4 CYTH domain K01768,K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000005483 181.0
SHD1_k127_3075409_5 - - - - 0.000000000000000000000000000000000000001418 151.0
SHD1_k127_3075409_6 Iron permease FTR1 K07243 - - 0.000000000000000008297 94.0
SHD1_k127_3082269_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 608.0
SHD1_k127_3082269_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 549.0
SHD1_k127_3093714_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.823e-314 969.0
SHD1_k127_3093714_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 9.746e-205 646.0
SHD1_k127_3093714_2 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 6.473e-198 624.0
SHD1_k127_3093714_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 285.0
SHD1_k127_3093714_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
SHD1_k127_3093714_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000001429 192.0
SHD1_k127_3093714_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000006018 151.0
SHD1_k127_3093714_7 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000004619 111.0
SHD1_k127_3098630_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 331.0
SHD1_k127_311954_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.502e-250 784.0
SHD1_k127_311954_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
SHD1_k127_311954_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 469.0
SHD1_k127_311954_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
SHD1_k127_311954_4 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000001594 223.0
SHD1_k127_311954_5 Regulatory protein, FmdB family - - - 0.0000000000000308 79.0
SHD1_k127_3137737_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 498.0
SHD1_k127_3137737_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.0000000000000000000000000000000000000000001131 167.0
SHD1_k127_3137737_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000001337 128.0
SHD1_k127_3139030_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 421.0
SHD1_k127_3139030_1 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 378.0
SHD1_k127_3139030_2 PFAM iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
SHD1_k127_3139030_3 Domain of unknown function (DUF1906) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 300.0
SHD1_k127_3139030_4 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 283.0
SHD1_k127_3139030_5 glucose sorbosone - - - 0.0000000000000000000000255 112.0
SHD1_k127_313999_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 286.0
SHD1_k127_3146840_0 permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 3.841e-195 621.0
SHD1_k127_3146840_1 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000001182 241.0
SHD1_k127_3147799_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 373.0
SHD1_k127_3147799_1 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
SHD1_k127_3147799_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000001069 205.0
SHD1_k127_3147799_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000001739 136.0
SHD1_k127_315344_0 Dehydrogenase K07077 - - 1.285e-231 723.0
SHD1_k127_315344_1 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 524.0
SHD1_k127_315344_2 photoreceptor activity K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 379.0
SHD1_k127_315344_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000004561 185.0
SHD1_k127_315344_4 Predicted membrane protein (DUF2127) - - - 0.00000000000000000000000000000002955 132.0
SHD1_k127_315344_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000693 120.0
SHD1_k127_315344_6 - - - - 0.0000000000000005238 85.0
SHD1_k127_3178779_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 503.0
SHD1_k127_3178779_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 404.0
SHD1_k127_3178779_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 388.0
SHD1_k127_3178779_3 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 321.0
SHD1_k127_3178779_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 327.0
SHD1_k127_3178779_5 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000004853 128.0
SHD1_k127_3204691_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 4.525e-274 851.0
SHD1_k127_3204691_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 406.0
SHD1_k127_3204691_2 lipoprotein YddW precursor K01189 - - - 0.0000000000000000000000000000000000000000007496 172.0
SHD1_k127_3204691_3 - - - - 0.0000000000000000000000000000000000000001709 156.0
SHD1_k127_322334_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 568.0
SHD1_k127_322334_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 346.0
SHD1_k127_322334_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000002597 198.0
SHD1_k127_322334_3 Tfp pilus assembly protein FimT - - - 0.0000000000000000001652 94.0
SHD1_k127_322334_4 - - - - 0.00000000000002137 82.0
SHD1_k127_322334_5 Rdx family K07401 - - 0.00000606 50.0
SHD1_k127_3248861_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 552.0
SHD1_k127_3248861_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 471.0
SHD1_k127_3248861_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000006448 249.0
SHD1_k127_3248861_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001039 234.0
SHD1_k127_325091_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
SHD1_k127_325091_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000009761 227.0
SHD1_k127_325091_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000005698 216.0
SHD1_k127_325091_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000001117 160.0
SHD1_k127_325091_4 FtsX-like permease family K02004 - - 0.000000002081 59.0
SHD1_k127_3262791_0 (ABC) transporter K06147,K06148 - - 5.322e-205 653.0
SHD1_k127_3262791_1 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 302.0
SHD1_k127_3262791_2 - - - - 0.0000000000000000000000000000000001314 143.0
SHD1_k127_3278026_0 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000004626 239.0
SHD1_k127_3278026_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000002009 206.0
SHD1_k127_3278026_2 ATPase activity K01990,K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000007225 203.0
SHD1_k127_3278026_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000009421 141.0
SHD1_k127_3293668_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 518.0
SHD1_k127_3293668_1 asparaginase activity K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 403.0
SHD1_k127_3293668_2 Lipocalin-like domain - - - 0.00000000000000000000000000001129 126.0
SHD1_k127_3293668_3 Domain of unknown function (DUF4918) - - - 0.0001123 48.0
SHD1_k127_3303764_0 Uncharacterized protein family (UPF0051) K09014 - - 2.714e-258 801.0
SHD1_k127_3303764_1 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000001285 226.0
SHD1_k127_3348693_0 mannonate dehydratase activity K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 512.0
SHD1_k127_3348693_1 Glycosyl Hydrolase Family 88 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 414.0
SHD1_k127_3348693_2 transmembrane transporter activity K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 356.0
SHD1_k127_335250_0 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 481.0
SHD1_k127_335250_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000005035 212.0
SHD1_k127_335250_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000002763 157.0
SHD1_k127_335250_3 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000001515 147.0
SHD1_k127_3358532_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 329.0
SHD1_k127_3358532_1 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
SHD1_k127_3358532_2 Amino acid permease - - - 0.00000006417 56.0
SHD1_k127_340113_0 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 587.0
SHD1_k127_3401487_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 547.0
SHD1_k127_3401487_1 Copper resistance protein CopC K14166 - - 0.000000000000000006843 97.0
SHD1_k127_3401487_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000008292 81.0
SHD1_k127_3432178_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.339e-307 949.0
SHD1_k127_3432178_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 507.0
SHD1_k127_3432178_2 TipAS antibiotic-recognition domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006568 255.0
SHD1_k127_3432178_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008164 255.0
SHD1_k127_3432178_4 - - - - 0.0000000000005376 74.0
SHD1_k127_3434767_0 von Willebrand factor (vWF) type A domain - - - 1.327e-197 619.0
SHD1_k127_3434767_1 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 471.0
SHD1_k127_3434767_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
SHD1_k127_3448179_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003219 271.0
SHD1_k127_3448179_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000008029 207.0
SHD1_k127_3448179_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000008767 202.0
SHD1_k127_3448179_3 - - - - 0.00000000000000000000005292 109.0
SHD1_k127_3448179_4 - - - - 0.00000000000000000002057 104.0
SHD1_k127_3454359_0 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 597.0
SHD1_k127_3454359_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 410.0
SHD1_k127_3454359_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 340.0
SHD1_k127_3454359_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000009024 81.0
SHD1_k127_3455470_0 tRNA wobble adenosine to inosine editing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002626 263.0
SHD1_k127_3455470_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000001278 190.0
SHD1_k127_3459325_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 290.0
SHD1_k127_3459325_1 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000004375 228.0
SHD1_k127_3459325_2 - - - - 0.00000000000000000000000000000001024 143.0
SHD1_k127_3459325_3 methyltransferase activity - - - 0.00000000000000000000000006133 113.0
SHD1_k127_3468572_0 PFAM Amidase - - - 6.699e-198 634.0
SHD1_k127_3468572_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 473.0
SHD1_k127_3478484_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 375.0
SHD1_k127_3478484_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000836 273.0
SHD1_k127_3478484_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000001006 143.0
SHD1_k127_3478484_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000001398 137.0
SHD1_k127_3478484_4 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.000000000000000000000000004707 117.0
SHD1_k127_3478484_5 Methyltransferase type 12 - - - 0.00000000000000000005499 105.0
SHD1_k127_3484342_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 485.0
SHD1_k127_3484342_1 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 482.0
SHD1_k127_3484342_2 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 474.0
SHD1_k127_3484342_3 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 397.0
SHD1_k127_3484342_4 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003363 251.0
SHD1_k127_3484342_5 NmrA-like family - - - 0.000000000000000000000000000000000003301 146.0
SHD1_k127_3484342_6 - - - - 0.00000000000000000000000008019 116.0
SHD1_k127_3484342_7 Belongs to the MtfA family K09933 - - 0.00000000008417 63.0
SHD1_k127_349412_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.166e-231 739.0
SHD1_k127_349412_1 ABC transporter K02056 - 3.6.3.17 7.737e-203 645.0
SHD1_k127_349412_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 521.0
SHD1_k127_349412_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 501.0
SHD1_k127_349412_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 454.0
SHD1_k127_349412_5 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 395.0
SHD1_k127_349412_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000003882 164.0
SHD1_k127_349412_7 epimerase - - - 0.000000000000000000000004356 102.0
SHD1_k127_3499727_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 368.0
SHD1_k127_3499727_1 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
SHD1_k127_3499727_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 305.0
SHD1_k127_3499727_3 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000014 207.0
SHD1_k127_3499727_4 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.0000000000000001028 79.0
SHD1_k127_3501743_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 389.0
SHD1_k127_3501743_1 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 331.0
SHD1_k127_3501743_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.00000000000000000000000000000000000000000000000007138 190.0
SHD1_k127_3501743_3 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000002069 155.0
SHD1_k127_3501743_4 Trm112p-like protein K09791 - - 0.0000000000000000000000167 102.0
SHD1_k127_3501743_5 PFAM Glycosyl K12994 - 2.4.1.349 0.00000000000000000001055 100.0
SHD1_k127_3528917_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 337.0
SHD1_k127_3528917_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000003571 222.0
SHD1_k127_3528917_2 heat shock protein binding - - - 0.0000000000000000000000000000000003953 143.0
SHD1_k127_3528917_3 PFAM Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.000006755 55.0
SHD1_k127_3528917_4 Roadblock/LC7 domain - - - 0.0005863 49.0
SHD1_k127_3535411_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 428.0
SHD1_k127_3535411_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 385.0
SHD1_k127_3535411_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 355.0
SHD1_k127_3535411_3 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000000003908 223.0
SHD1_k127_3542091_0 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 302.0
SHD1_k127_3542091_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001715 289.0
SHD1_k127_3542091_2 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000000000000004663 190.0
SHD1_k127_3542091_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000001022 161.0
SHD1_k127_3543046_0 FMN reductase (NADPH) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 289.0
SHD1_k127_3543046_1 - - - - 0.00000000000000000008732 93.0
SHD1_k127_3543046_2 Domain of unknown function (DUF4010) - - - 0.0000000194 59.0
SHD1_k127_3544385_0 Belongs to the allantoicase family K01477 GO:0003674,GO:0003824,GO:0004037,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 514.0
SHD1_k127_3544385_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000013 246.0
SHD1_k127_3559071_0 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 398.0
SHD1_k127_3559071_1 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001666 272.0
SHD1_k127_3559071_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000001687 173.0
SHD1_k127_3559071_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000001273 83.0
SHD1_k127_3559267_0 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 526.0
SHD1_k127_3559267_1 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009781 243.0
SHD1_k127_3559267_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000004337 162.0
SHD1_k127_3559267_3 Protein of unknown function (DUF2867) - - - 0.0000000000000003509 81.0
SHD1_k127_3559267_4 thioesterase' K07107 - - 0.00000006922 59.0
SHD1_k127_3585805_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 336.0
SHD1_k127_3585805_1 membrane organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 351.0
SHD1_k127_3585805_2 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000002895 151.0
SHD1_k127_3585805_3 SdiA-regulated - - - 0.000000000000000000000000000000191 135.0
SHD1_k127_3585805_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000007747 81.0
SHD1_k127_3594640_0 Glutamine synthetase, catalytic domain K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001543 277.0
SHD1_k127_3594640_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000004468 151.0
SHD1_k127_3598429_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 467.0
SHD1_k127_3598429_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004754 296.0
SHD1_k127_360159_0 Fructose-bisphosphate aldolase class-II - - - 2.615e-197 622.0
SHD1_k127_360159_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 608.0
SHD1_k127_360159_2 YtxH-like protein - - - 0.0000000000000000000000000000000001216 139.0
SHD1_k127_3605774_0 CarboxypepD_reg-like domain - - - 1.871e-290 922.0
SHD1_k127_3605774_1 Pfam:SusD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 452.0
SHD1_k127_3612648_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 494.0
SHD1_k127_3612648_1 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 475.0
SHD1_k127_3612648_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
SHD1_k127_3612648_3 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000001422 186.0
SHD1_k127_3612648_4 - - - - 0.00000000000000000000000000000000000001316 147.0
SHD1_k127_3612648_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000002469 128.0
SHD1_k127_3612648_6 LysM domain - - - 0.000000000000000000000000000004425 121.0
SHD1_k127_3614601_0 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 531.0
SHD1_k127_3614601_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
SHD1_k127_3614601_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000005583 141.0
SHD1_k127_3616053_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 490.0
SHD1_k127_3616053_1 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 325.0
SHD1_k127_3616053_2 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 319.0
SHD1_k127_3616053_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000009872 250.0
SHD1_k127_3618324_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.568e-199 627.0
SHD1_k127_3618324_1 protein tyrosine kinase activity K16692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 354.0
SHD1_k127_3618324_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 299.0
SHD1_k127_3618324_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000000000000006578 243.0
SHD1_k127_3618324_4 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.000000000000000000000000000000000000000000000000000000001495 202.0
SHD1_k127_3618324_5 - - - - 0.0000000000000000000000000000000000000000000008447 169.0
SHD1_k127_3619246_0 Domain of unknown function (DUF5117) - - - 1.449e-260 827.0
SHD1_k127_3619246_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 590.0
SHD1_k127_3619246_2 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 417.0
SHD1_k127_3619246_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 396.0
SHD1_k127_3629119_0 peptidase - - - 5.091e-210 666.0
SHD1_k127_3629119_1 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
SHD1_k127_3629119_2 Subtilase family - - - 0.00000000000000000004326 93.0
SHD1_k127_3639995_0 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 511.0
SHD1_k127_3639995_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 489.0
SHD1_k127_3639995_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 364.0
SHD1_k127_3639995_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 366.0
SHD1_k127_3639995_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 305.0
SHD1_k127_3639995_5 3D domain protein - - - 0.0000000000000000000000000000000000004821 148.0
SHD1_k127_3642449_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 535.0
SHD1_k127_3642449_1 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000000001276 258.0
SHD1_k127_3642449_2 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000001068 220.0
SHD1_k127_3642449_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000002189 174.0
SHD1_k127_3642449_4 COG1596 Periplasmic protein involved in polysaccharide export K20988 - - 0.0000000001518 70.0
SHD1_k127_3648287_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 570.0
SHD1_k127_3648287_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 486.0
SHD1_k127_3648287_10 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000009404 66.0
SHD1_k127_3648287_11 cellulase activity - - - 0.000004306 55.0
SHD1_k127_3648287_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 444.0
SHD1_k127_3648287_3 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 354.0
SHD1_k127_3648287_4 polyketide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001769 275.0
SHD1_k127_3648287_5 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 267.0
SHD1_k127_3648287_6 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007588 250.0
SHD1_k127_3648287_7 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000001502 134.0
SHD1_k127_3648287_8 protein kinase activity - - - 0.0000000000000000000000000003887 116.0
SHD1_k127_3648287_9 Dodecin K09165 - - 0.000000000000000000005429 93.0
SHD1_k127_3655474_0 Flavin containing amine oxidoreductase - - - 9.905e-198 629.0
SHD1_k127_3655474_1 Transcription factor zinc-finger K09981 - - 0.0000000000000000000001007 101.0
SHD1_k127_3655474_2 Ferric reductase like transmembrane component - - - 0.00000000000000002409 86.0
SHD1_k127_3655474_3 - - - - 0.00000000000005846 76.0
SHD1_k127_3655474_4 Flavin containing amine oxidoreductase - - - 0.000003198 55.0
SHD1_k127_367305_0 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 542.0
SHD1_k127_367305_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 329.0
SHD1_k127_3680531_0 CarboxypepD_reg-like domain - - - 1.349e-228 730.0
SHD1_k127_3680531_1 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 336.0
SHD1_k127_3685745_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 449.0
SHD1_k127_3685745_1 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000000000000001409 192.0
SHD1_k127_3691982_0 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 563.0
SHD1_k127_3691982_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 380.0
SHD1_k127_3691982_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001197 224.0
SHD1_k127_3714783_0 Amidohydrolase family - - - 5.236e-232 732.0
SHD1_k127_3714783_1 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 497.0
SHD1_k127_3714783_2 - - - - 0.000000000000000000000000000000000000000000000000000001111 199.0
SHD1_k127_3714783_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000002611 94.0
SHD1_k127_3714783_4 family 18 - - - 0.0000001455 63.0
SHD1_k127_3734921_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 301.0
SHD1_k127_3734921_1 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004746 291.0
SHD1_k127_3734921_2 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001953 283.0
SHD1_k127_3734921_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
SHD1_k127_3734921_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 262.0
SHD1_k127_3742925_0 Cellulose synthase K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 542.0
SHD1_k127_3742925_2 Tetratricopeptide repeat - - - 0.000007936 58.0
SHD1_k127_3747232_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 370.0
SHD1_k127_3747232_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
SHD1_k127_3747232_2 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 360.0
SHD1_k127_3747232_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000007616 150.0
SHD1_k127_3747232_4 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000001446 110.0
SHD1_k127_3753306_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 396.0
SHD1_k127_3753306_1 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 398.0
SHD1_k127_3753306_2 response regulator K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
SHD1_k127_3753306_3 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000006822 202.0
SHD1_k127_3753306_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000001672 168.0
SHD1_k127_3758446_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 502.0
SHD1_k127_3758446_1 Rieske (2fe-2S) K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 450.0
SHD1_k127_3758446_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000007247 228.0
SHD1_k127_3758446_3 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000002599 169.0
SHD1_k127_3758446_4 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000005023 160.0
SHD1_k127_3758446_5 - - - - 0.00000000000004452 81.0
SHD1_k127_375993_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.085e-200 633.0
SHD1_k127_375993_1 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 260.0
SHD1_k127_375993_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000008892 77.0
SHD1_k127_375993_3 - - - - 0.0000000000004334 80.0
SHD1_k127_375993_4 Zinc dependent phospholipase C - - - 0.000000003847 60.0
SHD1_k127_3776533_0 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 487.0
SHD1_k127_3776533_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000001826 255.0
SHD1_k127_3776533_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000003978 54.0
SHD1_k127_3784880_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 368.0
SHD1_k127_3800058_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 586.0
SHD1_k127_3800058_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000006752 234.0
SHD1_k127_3801034_0 Sortilin, neurotensin receptor 3, - - - 7.95e-283 881.0
SHD1_k127_3801034_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000005773 213.0
SHD1_k127_3804996_0 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 355.0
SHD1_k127_3804996_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001195 229.0
SHD1_k127_3804996_2 PFAM Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000008893 241.0
SHD1_k127_3804996_4 - - - - 0.000000000000000000000000000000000000000000000001649 194.0
SHD1_k127_3804996_5 PFAM DegT DnrJ EryC1 StrS aminotransferase K13010 - 2.6.1.102 0.00000000000000003348 81.0
SHD1_k127_3810001_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1557.0
SHD1_k127_3810001_1 TonB-linked outer membrane protein, SusC RagA family - - - 0.0 1407.0
SHD1_k127_3810001_2 PFAM Bile acid sodium symporter K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 534.0
SHD1_k127_3810001_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 529.0
SHD1_k127_3810001_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 416.0
SHD1_k127_3810001_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 410.0
SHD1_k127_3810001_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
SHD1_k127_3810001_7 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 330.0
SHD1_k127_3819768_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 462.0
SHD1_k127_3819768_1 Domain of unknown function (DUF5118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 304.0
SHD1_k127_3833236_0 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 5.671e-206 655.0
SHD1_k127_3833236_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000004742 261.0
SHD1_k127_3833236_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000001824 188.0
SHD1_k127_3833236_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000005755 66.0
SHD1_k127_3833236_4 Carbamoyltransferase C-terminus K00612 - - 0.0002065 44.0
SHD1_k127_384248_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 542.0
SHD1_k127_384248_1 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000008209 161.0
SHD1_k127_3844757_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 3.734e-257 824.0
SHD1_k127_3844757_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 322.0
SHD1_k127_3844757_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 307.0
SHD1_k127_3844757_3 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000000313 196.0
SHD1_k127_3855410_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 576.0
SHD1_k127_3855410_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 537.0
SHD1_k127_3855410_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 537.0
SHD1_k127_3855410_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 513.0
SHD1_k127_3855410_4 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 345.0
SHD1_k127_3856102_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 357.0
SHD1_k127_3856102_1 methyltransferase - - - 0.000000000000000000000000000000000004018 143.0
SHD1_k127_3859106_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 552.0
SHD1_k127_3859106_1 methyltransferase activity - - - 0.00000000000000000000000000000002004 132.0
SHD1_k127_3859106_2 - - - - 0.000000000000003871 86.0
SHD1_k127_3863927_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000288 283.0
SHD1_k127_3863927_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
SHD1_k127_3863927_2 - - - - 0.00000000000000000000000002839 118.0
SHD1_k127_3863927_3 Peptidase M15 - - - 0.000000000000000000004666 94.0
SHD1_k127_3880729_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 409.0
SHD1_k127_3880729_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 372.0
SHD1_k127_3880729_2 Zn-dependent protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 313.0
SHD1_k127_3880729_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000001607 131.0
SHD1_k127_3883109_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.152e-234 734.0
SHD1_k127_3883109_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 535.0
SHD1_k127_3883109_2 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 430.0
SHD1_k127_3883109_3 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 357.0
SHD1_k127_3883109_4 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 297.0
SHD1_k127_3883109_5 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000000000000000000000000353 201.0
SHD1_k127_3883109_6 - - - - 0.00000000000000000000000000000000000000000000000001053 191.0
SHD1_k127_3883109_7 function. Source PGD - - - 0.000000002702 59.0
SHD1_k127_3888055_0 - - - - 0.00000000000000000000000003166 121.0
SHD1_k127_3888055_1 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.000000000000000004563 88.0
SHD1_k127_3888055_2 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000000000000004439 86.0
SHD1_k127_3888055_3 Domain of unknown function (DUF1736) - - - 0.00000112 60.0
SHD1_k127_3918515_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 593.0
SHD1_k127_3918515_1 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 337.0
SHD1_k127_3918515_2 HAMP domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006292 283.0
SHD1_k127_3918515_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000007049 49.0
SHD1_k127_3924833_0 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 473.0
SHD1_k127_3924833_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000279 160.0
SHD1_k127_3924833_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000002595 133.0
SHD1_k127_3949920_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 356.0
SHD1_k127_3949920_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 347.0
SHD1_k127_3949920_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005292 252.0
SHD1_k127_3949920_3 S23 ribosomal protein - - - 0.000000000000000003222 91.0
SHD1_k127_3970941_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 384.0
SHD1_k127_3970941_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006091 278.0
SHD1_k127_3970941_2 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000008532 248.0
SHD1_k127_3970941_3 - K01865 - 5.4.4.1 0.0000000000000000000000000000000000000000000001329 175.0
SHD1_k127_3970941_4 - - - - 0.000000000000000000000000000000000000000000001242 172.0
SHD1_k127_3970941_5 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000001508 153.0
SHD1_k127_3970941_6 - - - - 0.00000000000000000000000000000000000000534 148.0
SHD1_k127_3970941_7 methyltransferase activity - - - 0.0000000000003546 75.0
SHD1_k127_3970941_8 - - - - 0.000000002629 63.0
SHD1_k127_3970941_9 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00009787 45.0
SHD1_k127_3982397_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 404.0
SHD1_k127_3982397_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 359.0
SHD1_k127_3982397_10 - - - - 0.00000000000005938 78.0
SHD1_k127_3982397_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000009904 264.0
SHD1_k127_3982397_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000009281 236.0
SHD1_k127_3982397_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
SHD1_k127_3982397_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000003182 207.0
SHD1_k127_3982397_6 - - - - 0.0000000000000000000000000000000000000000000000001853 193.0
SHD1_k127_3982397_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000008597 156.0
SHD1_k127_3982397_8 Ribosomal protein S16 K02959 - - 0.00000000000000000000000000000000002697 138.0
SHD1_k127_3982397_9 - - - - 0.0000000000000000000000000001053 126.0
SHD1_k127_3984373_0 DeoC/LacD family aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 436.0
SHD1_k127_3984373_1 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004441 278.0
SHD1_k127_3984373_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007493 276.0
SHD1_k127_4012502_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 7.965e-285 918.0
SHD1_k127_4012502_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 478.0
SHD1_k127_4012502_2 Domain of unknown function (DUF4173) - - - 0.00000000000000000000000000000000000636 154.0
SHD1_k127_403651_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 421.0
SHD1_k127_403651_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 369.0
SHD1_k127_403651_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003729 286.0
SHD1_k127_403651_3 - - - - 0.0000000000000000000000000000000001059 143.0
SHD1_k127_403651_4 subunit of a heme lyase K02198,K02200 - - 0.000000000000000000000001025 109.0
SHD1_k127_403651_5 Polysulphide reductase, NrfD K00185 - - 0.000000000000000173 81.0
SHD1_k127_4037114_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 1.462e-247 777.0
SHD1_k127_4037114_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 9.145e-200 628.0
SHD1_k127_4037114_10 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000854 125.0
SHD1_k127_4037114_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000015 115.0
SHD1_k127_4037114_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 484.0
SHD1_k127_4037114_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 478.0
SHD1_k127_4037114_4 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 381.0
SHD1_k127_4037114_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 335.0
SHD1_k127_4037114_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 289.0
SHD1_k127_4037114_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002192 268.0
SHD1_k127_4037114_8 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000001432 225.0
SHD1_k127_4037114_9 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000221 175.0
SHD1_k127_4048884_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 339.0
SHD1_k127_4048884_1 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
SHD1_k127_4048884_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005541 276.0
SHD1_k127_4048884_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000438 230.0
SHD1_k127_4048884_4 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000003416 201.0
SHD1_k127_4063702_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 488.0
SHD1_k127_4063702_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 438.0
SHD1_k127_4063702_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000005269 216.0
SHD1_k127_4064535_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
SHD1_k127_4064535_1 SURF1 family K14998 - - 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
SHD1_k127_4085332_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 1.541e-299 934.0
SHD1_k127_4085332_1 transporter - - - 3.517e-201 643.0
SHD1_k127_4085332_2 - - - - 0.000000000000000000000000000000000000002693 150.0
SHD1_k127_4085332_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000002892 139.0
SHD1_k127_4110219_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1731.0
SHD1_k127_4110219_1 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000006505 210.0
SHD1_k127_4110219_2 Ribosomal L28 family K02902 - - 0.0000000000000000000000000000001063 125.0
SHD1_k127_4110219_3 Ribosomal protein L17 K02879 - - 0.000000000000005198 74.0
SHD1_k127_4123908_0 Bacterial membrane protein YfhO - - - 5.013e-248 792.0
SHD1_k127_4123908_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000005832 204.0
SHD1_k127_4123908_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000002021 167.0
SHD1_k127_4131010_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000002722 233.0
SHD1_k127_4131010_1 ErfK ybiS ycfS ynhG family protein K19234 - - 0.000000000000000000000000000000000000000000000000000009523 196.0
SHD1_k127_4131010_2 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000219 110.0
SHD1_k127_4131010_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000005501 85.0
SHD1_k127_4131010_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000325 70.0
SHD1_k127_4137389_0 cellular manganese ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 368.0
SHD1_k127_4137389_1 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001042 272.0
SHD1_k127_4137389_2 PDZ domain (Also known as DHR or GLGF) - - - 0.00000000008168 72.0
SHD1_k127_4139517_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 507.0
SHD1_k127_4139517_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 349.0
SHD1_k127_4139517_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000001835 126.0
SHD1_k127_4139517_3 FR47-like protein - - - 0.000000000000000004958 96.0
SHD1_k127_4139517_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000003794 74.0
SHD1_k127_4139651_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 539.0
SHD1_k127_4139651_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 326.0
SHD1_k127_4139651_2 cellular response to dsDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002537 264.0
SHD1_k127_4139651_3 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000004164 216.0
SHD1_k127_4139651_4 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000001353 190.0
SHD1_k127_4139651_5 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000006457 123.0
SHD1_k127_4139651_6 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000003229 123.0
SHD1_k127_4140993_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002048 276.0
SHD1_k127_4140993_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000006594 158.0
SHD1_k127_4140993_2 - - - - 0.000000000000000000000000000000000000001488 162.0
SHD1_k127_4140993_3 membrane protein involved in D-alanine export - - - 0.00000000000000000000000001888 114.0
SHD1_k127_4146425_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 457.0
SHD1_k127_4146425_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 298.0
SHD1_k127_4151902_0 Zinc carboxypeptidase - - - 0.0 1181.0
SHD1_k127_4151902_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 490.0
SHD1_k127_4151902_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000004645 184.0
SHD1_k127_4151902_3 methyltransferase - - - 0.000000000001419 70.0
SHD1_k127_4153884_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 5.874e-300 927.0
SHD1_k127_4153884_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 493.0
SHD1_k127_4153884_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000002667 189.0
SHD1_k127_4153884_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000001894 140.0
SHD1_k127_4154045_0 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005315 233.0
SHD1_k127_4154045_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000008211 156.0
SHD1_k127_4156542_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.379e-255 791.0
SHD1_k127_4156542_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000009123 136.0
SHD1_k127_4156542_2 - - - - 0.0000000000000000000000000000000002552 134.0
SHD1_k127_4156542_3 - - - - 0.00000000000000000000000001871 115.0
SHD1_k127_4156542_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000009535 113.0
SHD1_k127_4157704_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 9.539e-239 745.0
SHD1_k127_4157704_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 561.0
SHD1_k127_4157704_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 484.0
SHD1_k127_4157704_3 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
SHD1_k127_4157704_4 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000004165 220.0
SHD1_k127_4157704_5 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000001081 122.0
SHD1_k127_4157704_6 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000004698 74.0
SHD1_k127_4157704_7 PFAM nitrogen-fixing NifU domain protein - - - 0.0001543 52.0
SHD1_k127_4164253_0 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000001318 183.0
SHD1_k127_4164253_1 Iron-regulated membrane protein K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000001726 174.0
SHD1_k127_4164253_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000006075 164.0
SHD1_k127_4164253_3 cobalamin binding K22491 - - 0.00000000000000007427 81.0
SHD1_k127_4164253_4 CHAD - - - 0.00000000001207 69.0
SHD1_k127_4168392_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.052e-251 784.0
SHD1_k127_4168392_1 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 556.0
SHD1_k127_4171106_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 366.0
SHD1_k127_4171106_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 313.0
SHD1_k127_4171106_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 298.0
SHD1_k127_4171106_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000006475 166.0
SHD1_k127_4171106_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000001866 116.0
SHD1_k127_4171106_5 - - - - 0.000000000000000000003543 102.0
SHD1_k127_4171106_6 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0001269 48.0
SHD1_k127_4173505_0 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004245 279.0
SHD1_k127_4176776_0 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 518.0
SHD1_k127_4176776_1 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 351.0
SHD1_k127_4176776_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000001565 132.0
SHD1_k127_4176776_11 - - - - 0.00000000000000000000005162 101.0
SHD1_k127_4176776_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 317.0
SHD1_k127_4176776_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 298.0
SHD1_k127_4176776_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 293.0
SHD1_k127_4176776_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002148 267.0
SHD1_k127_4176776_6 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000565 205.0
SHD1_k127_4176776_7 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000003649 172.0
SHD1_k127_4176776_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000001153 169.0
SHD1_k127_4176776_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000669 167.0
SHD1_k127_4180013_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 434.0
SHD1_k127_4180013_1 - - - - 0.00000000000000000000000000000000000000000000000000000000002133 222.0
SHD1_k127_4182922_0 Sortilin, neurotensin receptor 3, - - - 0.0 1369.0
SHD1_k127_4182922_1 ABC transporter K06020 - 3.6.3.25 1.403e-258 807.0
SHD1_k127_4182922_10 - - - - 0.00000000000000000000000000000000000000000000003664 185.0
SHD1_k127_4182922_11 CoA binding domain K06929 - - 0.00000000000000000000000000000000000001029 153.0
SHD1_k127_4182922_13 Haem-binding domain - - - 0.000000000000000002414 93.0
SHD1_k127_4182922_14 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000003846 90.0
SHD1_k127_4182922_15 Cupin domain - - - 0.0000000000000007621 82.0
SHD1_k127_4182922_16 CHASE3 domain - - - 0.00000005216 61.0
SHD1_k127_4182922_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 545.0
SHD1_k127_4182922_3 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 458.0
SHD1_k127_4182922_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 332.0
SHD1_k127_4182922_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 295.0
SHD1_k127_4182922_6 iron-nicotianamine transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003867 264.0
SHD1_k127_4182922_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000001024 200.0
SHD1_k127_4182922_8 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000001156 186.0
SHD1_k127_4182922_9 - - - - 0.00000000000000000000000000000000000000000000003237 177.0
SHD1_k127_4196422_0 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 474.0
SHD1_k127_4196422_1 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000008843 227.0
SHD1_k127_4196422_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000004639 196.0
SHD1_k127_4196422_3 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.00000000000000000000000000000000000000001221 162.0
SHD1_k127_4196422_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000005419 128.0
SHD1_k127_4196422_5 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.00000002815 55.0
SHD1_k127_4209455_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 550.0
SHD1_k127_4209455_1 heat shock protein binding - - - 0.0000000000000000000000000000124 136.0
SHD1_k127_4209455_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000002638 89.0
SHD1_k127_4219241_0 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 409.0
SHD1_k127_4219241_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 335.0
SHD1_k127_4223864_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 3.209e-240 765.0
SHD1_k127_4223864_1 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000003617 212.0
SHD1_k127_4223864_2 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000005346 145.0
SHD1_k127_4225294_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.964e-299 927.0
SHD1_k127_4225294_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 7.158e-213 668.0
SHD1_k127_4225294_2 Protein of unknown function (DUF512) - - - 1.256e-200 632.0
SHD1_k127_4225294_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 352.0
SHD1_k127_4225294_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000004201 202.0
SHD1_k127_4229899_0 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 430.0
SHD1_k127_4229899_1 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000009293 141.0
SHD1_k127_4229899_2 S4 RNA-binding domain K04762 - - 0.00000000000000000000000000000000003952 138.0
SHD1_k127_4238683_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 5.497e-223 698.0
SHD1_k127_4238683_1 Sugar (and other) transporter - - - 3.964e-204 643.0
SHD1_k127_4238683_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 536.0
SHD1_k127_4238683_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 381.0
SHD1_k127_4238683_4 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
SHD1_k127_4238683_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006367 253.0
SHD1_k127_4238683_6 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000001637 160.0
SHD1_k127_4238683_7 Zinc finger domain - - - 0.000000000000000000000002025 115.0
SHD1_k127_4244111_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 521.0
SHD1_k127_4244111_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 354.0
SHD1_k127_4246865_0 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 429.0
SHD1_k127_4246865_1 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000001905 193.0
SHD1_k127_4246865_2 - - - - 0.00000000461 58.0
SHD1_k127_424761_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.926e-231 722.0
SHD1_k127_424761_1 metalloendopeptidase activity K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 554.0
SHD1_k127_424761_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 460.0
SHD1_k127_424761_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 414.0
SHD1_k127_424761_4 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 340.0
SHD1_k127_424761_5 - - - - 0.000000000000000000000000001378 114.0
SHD1_k127_4247810_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 589.0
SHD1_k127_4247810_1 Surface antigen K07277,K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 533.0
SHD1_k127_4265672_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 383.0
SHD1_k127_4265672_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 344.0
SHD1_k127_4265672_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000007853 229.0
SHD1_k127_4266626_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 346.0
SHD1_k127_4266626_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007827 289.0
SHD1_k127_4266626_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 278.0
SHD1_k127_4266626_3 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005958 265.0
SHD1_k127_4273103_0 Dehydrogenase - - - 0.0 1003.0
SHD1_k127_4273103_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 399.0
SHD1_k127_4273103_10 - - - - 0.00000000000000000000000000000000000002654 149.0
SHD1_k127_4273103_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000002661 135.0
SHD1_k127_4273103_2 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 381.0
SHD1_k127_4273103_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 351.0
SHD1_k127_4273103_4 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 309.0
SHD1_k127_4273103_5 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001134 270.0
SHD1_k127_4273103_6 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001268 274.0
SHD1_k127_4273103_7 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000004599 183.0
SHD1_k127_4273103_8 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000002097 179.0
SHD1_k127_4273103_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000002618 158.0
SHD1_k127_4275080_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.438e-302 947.0
SHD1_k127_4275080_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.502e-233 724.0
SHD1_k127_4275080_2 O-acyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 419.0
SHD1_k127_4275080_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006652 273.0
SHD1_k127_4275080_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001507 270.0
SHD1_k127_4275080_5 - - - - 0.00000000000000000000000000000000000000000000000001952 187.0
SHD1_k127_4275080_6 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000003115 181.0
SHD1_k127_4282165_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.931e-299 928.0
SHD1_k127_4282165_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 412.0
SHD1_k127_4282165_2 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000001025 87.0
SHD1_k127_4286925_0 IMP dehydrogenase activity K03281 - - 2.836e-239 756.0
SHD1_k127_4286925_1 Uncharacterised conserved protein (DUF2156) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 393.0
SHD1_k127_4286925_2 Cysteine-rich CPXCG - - - 0.000000000000000000008563 94.0
SHD1_k127_4286925_4 - - - - 0.00000000001833 72.0
SHD1_k127_4297097_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1046.0
SHD1_k127_4297097_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 473.0
SHD1_k127_4297097_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 432.0
SHD1_k127_4297097_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 396.0
SHD1_k127_4297097_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 334.0
SHD1_k127_4297097_5 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 271.0
SHD1_k127_4297097_6 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000001136 213.0
SHD1_k127_4297097_7 - - - - 0.0000000000000000000000000000000000000000006355 164.0
SHD1_k127_4299929_0 ABC transporter K06158 - - 4.981e-197 634.0
SHD1_k127_4299929_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 602.0
SHD1_k127_4299929_10 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000001411 246.0
SHD1_k127_4299929_11 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000003136 214.0
SHD1_k127_4299929_2 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 476.0
SHD1_k127_4299929_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 448.0
SHD1_k127_4299929_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 385.0
SHD1_k127_4299929_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 369.0
SHD1_k127_4299929_6 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 302.0
SHD1_k127_4299929_7 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 297.0
SHD1_k127_4299929_8 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 264.0
SHD1_k127_4299929_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 262.0
SHD1_k127_4315888_0 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000339 254.0
SHD1_k127_4315888_1 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000006466 228.0
SHD1_k127_4327542_0 AAA domain K03546 - - 3.062e-218 704.0
SHD1_k127_4327542_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 436.0
SHD1_k127_4327542_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006451 269.0
SHD1_k127_4327542_3 - - - - 0.00000000127 63.0
SHD1_k127_4338137_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.975e-229 717.0
SHD1_k127_4338137_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 554.0
SHD1_k127_4338137_2 PFAM Acetyltransferase (GNAT) family - - - 0.000005234 56.0
SHD1_k127_4343011_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 408.0
SHD1_k127_4343011_1 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000003556 160.0
SHD1_k127_4350588_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.665e-229 725.0
SHD1_k127_4350588_1 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 426.0
SHD1_k127_4350588_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
SHD1_k127_4350588_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 331.0
SHD1_k127_4350588_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000009785 204.0
SHD1_k127_4350588_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000001271 198.0
SHD1_k127_4350588_6 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000009676 158.0
SHD1_k127_4350588_7 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000005702 117.0
SHD1_k127_4354738_0 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 452.0
SHD1_k127_4354738_1 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 456.0
SHD1_k127_4354738_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000002985 186.0
SHD1_k127_4354738_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000002824 123.0
SHD1_k127_4354738_4 Roadblock/LC7 domain K07131 - - 0.000000000000000000000002551 106.0
SHD1_k127_4354738_5 - - - - 0.00000000000000000000008804 111.0
SHD1_k127_4354738_6 Beta-lactamase superfamily domain - - - 0.0000000006944 61.0
SHD1_k127_4356408_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 8.977e-321 991.0
SHD1_k127_4356408_1 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 345.0
SHD1_k127_4356408_2 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 265.0
SHD1_k127_4356408_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000001912 235.0
SHD1_k127_4356408_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000007968 206.0
SHD1_k127_4356408_5 Response regulator, receiver K02282 - - 0.00000000000000000000000000000000000002392 158.0
SHD1_k127_4356408_6 - - - - 0.0000000000000000000000000003333 126.0
SHD1_k127_4356408_7 aspartic-type endopeptidase activity K02278,K02654 - 3.4.23.43 0.0000000000000000000000005791 111.0
SHD1_k127_4356408_8 Flp Fap pilin component K02651 - - 0.00008456 46.0
SHD1_k127_4356408_9 Flp/Fap pilin component K02651 - - 0.0001958 47.0
SHD1_k127_43619_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 417.0
SHD1_k127_43619_1 polysaccharide deacetylase K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 383.0
SHD1_k127_43619_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 333.0
SHD1_k127_43619_3 DNA-binding transcription factor activity - - - 0.00000000000000399 87.0
SHD1_k127_43619_4 Aspartyl protease - - - 0.000000000000005219 82.0
SHD1_k127_4368160_0 lysine biosynthetic process via aminoadipic acid - - - 5.615e-234 752.0
SHD1_k127_4368160_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 321.0
SHD1_k127_4371308_0 DinB superfamily K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 394.0
SHD1_k127_4371308_1 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000004787 266.0
SHD1_k127_4371308_2 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000003365 191.0
SHD1_k127_4381769_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 538.0
SHD1_k127_4381769_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 542.0
SHD1_k127_4381769_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 505.0
SHD1_k127_4381769_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 282.0
SHD1_k127_4381769_4 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000004633 219.0
SHD1_k127_4381769_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000004834 213.0
SHD1_k127_4381769_6 POT family K03305 - - 0.00000000000000000005004 92.0
SHD1_k127_4382941_0 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 438.0
SHD1_k127_4382941_1 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000104 257.0
SHD1_k127_4384563_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000003131 257.0
SHD1_k127_4384563_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002873 231.0
SHD1_k127_4384563_2 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000000002265 147.0
SHD1_k127_4384563_3 lytic transglycosylase activity - - - 0.000000000000002233 85.0
SHD1_k127_4406610_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 383.0
SHD1_k127_4406610_1 Peptidase M15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 296.0
SHD1_k127_4406610_2 Prokaryotic N-terminal methylation motif - - - 0.00000000000002155 81.0
SHD1_k127_4427183_0 Bacterial protein of unknown function (DUF885) - - - 1.334e-249 789.0
SHD1_k127_4427183_1 Conserved hypothetical protein 95 K00564 - 2.1.1.172 0.00000000000000000000000000000000003464 145.0
SHD1_k127_4438384_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 511.0
SHD1_k127_4438384_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 376.0
SHD1_k127_4438384_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004991 269.0
SHD1_k127_4444052_0 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 5.334e-209 679.0
SHD1_k127_4444052_1 Protein of unknown function (DUF3419) - - - 0.00000000000000000000000000000000000000000000000000000000000000009035 237.0
SHD1_k127_4444052_2 COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000212 223.0
SHD1_k127_4444052_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000001689 183.0
SHD1_k127_4444052_4 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.0000000000000000000000000000000000000000000007172 184.0
SHD1_k127_4470598_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 474.0
SHD1_k127_4470598_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 387.0
SHD1_k127_4470598_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000147 139.0
SHD1_k127_4470598_3 Aminotransferase class I and II K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 0.00000003677 55.0
SHD1_k127_4473031_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 5.092e-196 625.0
SHD1_k127_4473031_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 565.0
SHD1_k127_4473031_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 522.0
SHD1_k127_4473031_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 472.0
SHD1_k127_4473031_4 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000004505 211.0
SHD1_k127_4473031_5 YjbR - - - 0.000000000000000000000000000000000000000000000002649 176.0
SHD1_k127_4474851_0 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 448.0
SHD1_k127_4474851_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
SHD1_k127_4474851_2 response to abiotic stimulus K03086,K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 329.0
SHD1_k127_4474851_3 Ankyrin repeats (3 copies) - - - 0.0000004719 53.0
SHD1_k127_4497029_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.845e-245 766.0
SHD1_k127_4497029_1 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 314.0
SHD1_k127_4497029_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000002003 142.0
SHD1_k127_4497029_3 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000941 136.0
SHD1_k127_4497029_4 - - - - 0.000000000000000000000007892 108.0
SHD1_k127_4501286_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000004542 154.0
SHD1_k127_4501286_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000006788 85.0
SHD1_k127_4504545_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 460.0
SHD1_k127_4504545_1 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 439.0
SHD1_k127_4504545_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000008244 191.0
SHD1_k127_4504545_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000005248 181.0
SHD1_k127_4509972_0 Collagenase K08303 - - 0.0 1028.0
SHD1_k127_4509972_1 Carboxyl transferase domain - - - 4.726e-270 842.0
SHD1_k127_4509972_2 Acyclic terpene utilisation family protein AtuA - - - 2.103e-245 764.0
SHD1_k127_4509972_3 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 359.0
SHD1_k127_4509972_4 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000001874 252.0
SHD1_k127_4509972_5 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000006729 239.0
SHD1_k127_4509972_6 - - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
SHD1_k127_4509972_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000002413 131.0
SHD1_k127_451055_0 Clp amino terminal domain, pathogenicity island component K03696 - - 0.000000000000000000000000000000000000000000000009698 175.0
SHD1_k127_451055_1 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000001383 145.0
SHD1_k127_451055_2 sequence-specific DNA binding K07729 - - 0.00000000000005641 81.0
SHD1_k127_4517381_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 419.0
SHD1_k127_4517381_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 369.0
SHD1_k127_4517381_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000007141 263.0
SHD1_k127_4517381_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
SHD1_k127_4525979_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 518.0
SHD1_k127_4525979_1 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 422.0
SHD1_k127_4525979_2 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000005139 204.0
SHD1_k127_4525979_3 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000306 209.0
SHD1_k127_4527465_0 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 473.0
SHD1_k127_4527465_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 403.0
SHD1_k127_4527465_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 319.0
SHD1_k127_4527465_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009364 241.0
SHD1_k127_4527465_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000002518 214.0
SHD1_k127_4527465_5 DinB superfamily - - - 0.00000000000000000000000000000000002387 142.0
SHD1_k127_4532476_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 453.0
SHD1_k127_4532476_1 Hypothetical methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 445.0
SHD1_k127_4532476_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 319.0
SHD1_k127_4532476_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.0000000000000008089 83.0
SHD1_k127_4532476_4 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000005622 61.0
SHD1_k127_4532476_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0001485 45.0
SHD1_k127_4537943_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 555.0
SHD1_k127_4537943_1 aminopeptidase N - - - 0.0000000000000000000000000000608 130.0
SHD1_k127_4575657_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002147 283.0
SHD1_k127_4575657_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000005756 184.0
SHD1_k127_4575657_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000006786 126.0
SHD1_k127_4587572_0 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 549.0
SHD1_k127_4587572_1 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 356.0
SHD1_k127_4587572_2 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 0.000000000000000000000000000004133 124.0
SHD1_k127_4594656_0 Carboxypeptidase regulatory-like domain - - - 0.0 1043.0
SHD1_k127_4594656_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 463.0
SHD1_k127_4594656_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 403.0
SHD1_k127_4594656_3 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 286.0
SHD1_k127_4594656_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
SHD1_k127_4594656_5 - K21429 - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
SHD1_k127_4594656_6 Domain of unknown function (DUF4186) - - - 0.000000000000000000000000000000000000000000000000006081 182.0
SHD1_k127_4594656_7 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000001999 164.0
SHD1_k127_4594656_9 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000004377 125.0
SHD1_k127_4595997_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 386.0
SHD1_k127_4595997_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000007775 201.0
SHD1_k127_4595997_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000002075 153.0
SHD1_k127_4595997_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000002196 155.0
SHD1_k127_4599430_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 605.0
SHD1_k127_4599430_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 445.0
SHD1_k127_4599430_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000163 240.0
SHD1_k127_4599430_4 - - - - 0.00000000000209 73.0
SHD1_k127_4623803_0 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 460.0
SHD1_k127_4623803_1 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 272.0
SHD1_k127_4623803_2 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006742 251.0
SHD1_k127_4623803_3 PFAM DsrE DsrF-like family K09004 - - 0.000000000000000000000000000000003261 139.0
SHD1_k127_4623803_4 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000008959 126.0
SHD1_k127_4623803_6 - - - - 0.0000000008236 63.0
SHD1_k127_4632767_0 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 543.0
SHD1_k127_4632767_1 SNF2 family N-terminal domain - - - 0.000000000000000000000000000000000000000001765 174.0
SHD1_k127_4654815_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 587.0
SHD1_k127_4654815_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 374.0
SHD1_k127_4654815_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000001956 165.0
SHD1_k127_4697666_0 Redoxin K03564 - 1.11.1.15 0.000000000000000005858 83.0
SHD1_k127_4697666_1 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.000000000000005486 76.0
SHD1_k127_4697666_2 - - - - 0.00009187 53.0
SHD1_k127_4715634_0 cellulose binding - - - 0.0 1105.0
SHD1_k127_4715634_1 Dehydrogenase - - - 5.36e-199 629.0
SHD1_k127_4715634_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004318 235.0
SHD1_k127_4715634_12 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000009183 223.0
SHD1_k127_4715634_13 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000006938 190.0
SHD1_k127_4715634_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000004643 174.0
SHD1_k127_4715634_15 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000005975 151.0
SHD1_k127_4715634_16 SusD family K21572 - - 0.000000000000000000000000000000000758 147.0
SHD1_k127_4715634_17 - - - - 0.00000000000000000000000000000007888 128.0
SHD1_k127_4715634_18 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000002226 120.0
SHD1_k127_4715634_2 TonB-linked outer membrane protein, SusC RagA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 591.0
SHD1_k127_4715634_20 peptidase activity K21469 - 3.4.16.4 0.0000000001269 64.0
SHD1_k127_4715634_21 Domain of unknown function (DUF4397) - - - 0.0000000368 65.0
SHD1_k127_4715634_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 375.0
SHD1_k127_4715634_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 310.0
SHD1_k127_4715634_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 307.0
SHD1_k127_4715634_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 294.0
SHD1_k127_4715634_7 Beta-lactamase K21469 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001866 272.0
SHD1_k127_4715634_8 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000004319 268.0
SHD1_k127_4715634_9 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009296 259.0
SHD1_k127_4723716_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 589.0
SHD1_k127_4723716_1 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 416.0
SHD1_k127_4723716_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 361.0
SHD1_k127_4723716_3 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000019 281.0
SHD1_k127_4723716_4 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000004697 111.0
SHD1_k127_4723716_5 Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner K21594 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0032268,GO:0032270,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034250,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070013,GO:0070129,GO:0070131,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000112 - 0.000000001966 58.0
SHD1_k127_4749841_0 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 2.759e-197 621.0
SHD1_k127_4749841_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 586.0
SHD1_k127_4749841_2 TonB-dependent Receptor Plug Domain - - - 0.000000000000000002445 94.0
SHD1_k127_4755468_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 365.0
SHD1_k127_4755468_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 301.0
SHD1_k127_4755468_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000005096 202.0
SHD1_k127_4755468_3 Glycosyl transferases group 1 K19424 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 - 0.00000000000000000000001103 114.0
SHD1_k127_4755468_4 Glycosyl transferases group 1 - - - 0.000000000000000002509 94.0
SHD1_k127_4755468_5 Male sterility protein - - - 0.00000000000000002085 83.0
SHD1_k127_4755468_6 Glycosyltransferase like family 2 - - - 0.0000000000003057 72.0
SHD1_k127_4775845_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1143.0
SHD1_k127_4775845_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 474.0
SHD1_k127_4786364_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1328.0
SHD1_k127_4786364_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 392.0
SHD1_k127_4786364_10 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000003433 98.0
SHD1_k127_4786364_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000001037 70.0
SHD1_k127_4786364_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 373.0
SHD1_k127_4786364_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 333.0
SHD1_k127_4786364_4 - - - - 0.00000000000000000000000000000000000000000006761 172.0
SHD1_k127_4786364_5 - - - - 0.000000000000000000000000000000000001422 140.0
SHD1_k127_4786364_6 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000009167 134.0
SHD1_k127_4786364_7 Cold shock K03704 - - 0.00000000000000000000000000001143 120.0
SHD1_k127_4786364_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000008072 104.0
SHD1_k127_4786364_9 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000002726 108.0
SHD1_k127_4806336_0 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 559.0
SHD1_k127_4806336_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 556.0
SHD1_k127_4806336_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 545.0
SHD1_k127_4806336_3 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000002973 121.0
SHD1_k127_4806336_4 - - - - 0.00000000000000000000000001583 111.0
SHD1_k127_4806336_5 - - - - 0.000000000000000001488 87.0
SHD1_k127_4806336_6 - - - - 0.00000003692 57.0
SHD1_k127_4811188_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000009295 249.0
SHD1_k127_4811188_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000005941 205.0
SHD1_k127_4811188_2 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000006776 205.0
SHD1_k127_4817809_0 Carbohydrate family 9 binding domain-like - - - 2.884e-262 832.0
SHD1_k127_4817809_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000001427 181.0
SHD1_k127_4817809_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000004953 172.0
SHD1_k127_4817809_3 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000004313 143.0
SHD1_k127_4817809_4 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000002436 134.0
SHD1_k127_4819038_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 389.0
SHD1_k127_4819038_1 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 366.0
SHD1_k127_4819038_2 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
SHD1_k127_4819038_3 PFAM Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000008566 240.0
SHD1_k127_4819038_4 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.00000000000000000000000000000000000004778 158.0
SHD1_k127_4820413_0 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000000000000000000000000001485 203.0
SHD1_k127_4820413_1 CarboxypepD_reg-like domain - - - 0.000000003494 63.0
SHD1_k127_4820413_2 - - - - 0.00001281 53.0
SHD1_k127_482190_0 Zinc carboxypeptidase - - - 1.682e-319 985.0
SHD1_k127_482190_1 Membrane protein involved in cytochrome C biogenesis - - - 0.0000000000000000000000000000000000000000003564 169.0
SHD1_k127_483300_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.623e-279 867.0
SHD1_k127_483300_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
SHD1_k127_483300_2 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000001296 108.0
SHD1_k127_4843703_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 509.0
SHD1_k127_4843703_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 322.0
SHD1_k127_4843703_2 S4 RNA-binding domain K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 307.0
SHD1_k127_4843703_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 301.0
SHD1_k127_4843703_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000003406 233.0
SHD1_k127_4843703_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000003279 125.0
SHD1_k127_4843703_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000456 93.0
SHD1_k127_4843703_7 Zinc finger domain - - - 0.000000007785 61.0
SHD1_k127_4844173_0 Sodium:solute symporter family K14392 - - 1.976e-227 713.0
SHD1_k127_4844173_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 554.0
SHD1_k127_4844173_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 480.0
SHD1_k127_4844173_3 FMN reductase (NADPH) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 326.0
SHD1_k127_4844173_4 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 282.0
SHD1_k127_4844173_5 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000001229 213.0
SHD1_k127_4844173_6 - - - - 0.0000000000000000000000000000000000000000000000000000001116 200.0
SHD1_k127_4844173_7 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000117 171.0
SHD1_k127_4844173_8 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000001231 161.0
SHD1_k127_4844173_9 - - - - 0.0000000000000000000000000000000001493 141.0
SHD1_k127_4844656_0 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 385.0
SHD1_k127_4844656_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
SHD1_k127_4844656_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000002905 99.0
SHD1_k127_4846429_0 PFAM ABC transporter transmembrane K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 602.0
SHD1_k127_4846429_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 318.0
SHD1_k127_4846429_2 Belongs to the bacterial solute-binding protein 9 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 338.0
SHD1_k127_4846429_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001818 227.0
SHD1_k127_4846429_4 - - - - 0.00000000000000000000000000000000000000000000000000000000001823 222.0
SHD1_k127_4861273_0 E1-E2 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 544.0
SHD1_k127_4861273_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 363.0
SHD1_k127_4861273_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000001637 162.0
SHD1_k127_4861273_3 Universal stress protein family - - - 0.000006838 58.0
SHD1_k127_4864116_0 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000001409 184.0
SHD1_k127_4864116_1 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000000000002037 175.0
SHD1_k127_4868394_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 565.0
SHD1_k127_4868394_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 465.0
SHD1_k127_4868394_10 - - - - 0.000000000000001092 81.0
SHD1_k127_4868394_11 - - - - 0.000004138 55.0
SHD1_k127_4868394_2 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 374.0
SHD1_k127_4868394_3 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002794 231.0
SHD1_k127_4868394_4 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000004013 184.0
SHD1_k127_4868394_5 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000004646 158.0
SHD1_k127_4868394_6 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000000000000246 145.0
SHD1_k127_4868394_7 - - - - 0.000000000000000000000000000000002815 132.0
SHD1_k127_4868394_8 - - - - 0.0000000000000000000000165 103.0
SHD1_k127_4868394_9 Domain of unknown function (DUF4412) - - - 0.00000000000000002192 94.0
SHD1_k127_4869912_0 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 574.0
SHD1_k127_4869912_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 332.0
SHD1_k127_4869912_2 Tryptophan-rich sensory protein K05770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000393 245.0
SHD1_k127_4869912_3 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000000000000000003105 189.0
SHD1_k127_4869912_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000003038 179.0
SHD1_k127_4869912_5 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000002122 156.0
SHD1_k127_4869912_6 MgtC family K07507 - - 0.0000000000000000000000000000005745 126.0
SHD1_k127_4869912_7 - - - - 0.0000000000005351 78.0
SHD1_k127_4874939_0 Peptidase dimerisation domain - - - 3.331e-194 617.0
SHD1_k127_4874939_1 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 475.0
SHD1_k127_4874939_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 421.0
SHD1_k127_4874939_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000006631 114.0
SHD1_k127_4874939_4 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000001093 80.0
SHD1_k127_4874939_5 chitin binding - - - 0.000000001435 59.0
SHD1_k127_4893915_0 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 339.0
SHD1_k127_4893915_1 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000007259 243.0
SHD1_k127_4906657_0 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 570.0
SHD1_k127_4906657_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 491.0
SHD1_k127_4906657_2 4Fe-4S single cluster domain K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 323.0
SHD1_k127_4906657_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000002529 184.0
SHD1_k127_4906657_4 AntiSigma factor - - - 0.00000000000000000000000000000000006639 144.0
SHD1_k127_4906657_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000002204 142.0
SHD1_k127_4907685_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 561.0
SHD1_k127_4907685_1 Sporulation related domain - - - 0.00000000000000000000000000000000000003105 151.0
SHD1_k127_4910921_0 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 570.0
SHD1_k127_4910921_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 475.0
SHD1_k127_4910921_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000001206 79.0
SHD1_k127_4920772_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 552.0
SHD1_k127_4920772_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009649 271.0
SHD1_k127_4920772_2 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000000000000000000001502 188.0
SHD1_k127_4926868_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 426.0
SHD1_k127_4926868_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001057 282.0
SHD1_k127_4926868_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000006946 232.0
SHD1_k127_4926868_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000005751 123.0
SHD1_k127_4934113_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1330.0
SHD1_k127_4934113_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 3.804e-276 864.0
SHD1_k127_4934113_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 392.0
SHD1_k127_4938936_0 - - - - 0.000000000000000000000000000000000000000000001883 179.0
SHD1_k127_4938936_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000006936 149.0
SHD1_k127_4938936_2 - - - - 0.000002584 54.0
SHD1_k127_4940459_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 475.0
SHD1_k127_4940459_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000009046 215.0
SHD1_k127_4940459_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000005239 176.0
SHD1_k127_4947884_0 GMC oxidoreductase - - - 1.254e-218 692.0
SHD1_k127_4947884_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 503.0
SHD1_k127_4963041_0 HELICc2 K03722 - 3.6.4.12 1.187e-267 844.0
SHD1_k127_4963041_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 563.0
SHD1_k127_4963041_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 302.0
SHD1_k127_4963041_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 296.0
SHD1_k127_4963041_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009956 278.0
SHD1_k127_4963041_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000004908 237.0
SHD1_k127_4963041_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000004226 204.0
SHD1_k127_4963041_7 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000002004 174.0
SHD1_k127_4963041_8 - - - - 0.0000000000000000000000000000000000000000001968 172.0
SHD1_k127_4963041_9 - - - - 0.00000000000000000001772 99.0
SHD1_k127_4964589_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1189.0
SHD1_k127_4967393_0 Outer membrane protein beta-barrel family - - - 1.913e-301 949.0
SHD1_k127_4967393_1 Multicopper oxidase K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 345.0
SHD1_k127_4967393_10 - - - - 0.000000000000000000005792 102.0
SHD1_k127_4967393_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003465 242.0
SHD1_k127_4967393_3 Cytochrome c K00376,K02305,K17760 - 1.1.9.1,1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000132 221.0
SHD1_k127_4967393_4 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000001272 214.0
SHD1_k127_4967393_5 heme binding - - - 0.000000000000000000000000000000000000000000000000000000002044 211.0
SHD1_k127_4967393_6 - - - - 0.000000000000000000000000000000000000000000000000004882 190.0
SHD1_k127_4967393_7 DinB family - - - 0.00000000000000000000000000000000000000000000000002864 183.0
SHD1_k127_4967393_8 - - - - 0.0000000000000000000000000000000000002777 147.0
SHD1_k127_4967393_9 Surface antigen - - - 0.00000000000000000000000000000004251 131.0
SHD1_k127_497794_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.874e-215 677.0
SHD1_k127_497794_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.000000000000000000000000000000000000001171 156.0
SHD1_k127_497794_2 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.000000000000000000000000003795 111.0
SHD1_k127_4992585_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.401e-227 719.0
SHD1_k127_4992585_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000005467 264.0
SHD1_k127_4992585_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001122 240.0
SHD1_k127_4992585_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000004234 233.0
SHD1_k127_4992958_0 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000003737 194.0
SHD1_k127_4992958_1 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000003957 195.0
SHD1_k127_4992958_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000006694 149.0
SHD1_k127_4997781_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 425.0
SHD1_k127_4997781_1 YceI-like domain - - - 0.00000000000000006743 89.0
SHD1_k127_4997781_2 glyoxalase III activity K01259 - 3.4.11.5 0.00000000005042 70.0
SHD1_k127_4999111_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 3.081e-280 868.0
SHD1_k127_4999111_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 571.0
SHD1_k127_4999111_2 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 402.0
SHD1_k127_4999111_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000003089 124.0
SHD1_k127_500373_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 482.0
SHD1_k127_500373_1 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 466.0
SHD1_k127_500373_10 transferase activity, transferring acyl groups K03824,K15520 - 2.3.1.189 0.0000000000000000000000000002905 120.0
SHD1_k127_500373_2 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 451.0
SHD1_k127_500373_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 428.0
SHD1_k127_500373_4 dihydrofolate reductase activity K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000001734 229.0
SHD1_k127_500373_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000006587 184.0
SHD1_k127_500373_6 DinB family - - - 0.00000000000000000000000000000000000000000006464 166.0
SHD1_k127_500373_7 response to abiotic stimulus K03086,K06867 - - 0.00000000000000000000000000000000000000002482 155.0
SHD1_k127_500373_8 DinB superfamily - - - 0.00000000000000000000000000000000000001236 150.0
SHD1_k127_500373_9 DinB superfamily K07552 - - 0.0000000000000000000000000000002849 130.0
SHD1_k127_5004775_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.022e-292 917.0
SHD1_k127_5004775_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 435.0
SHD1_k127_5004775_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 411.0
SHD1_k127_5004775_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 296.0
SHD1_k127_5004775_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000005006 105.0
SHD1_k127_5020087_0 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 309.0
SHD1_k127_5020087_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
SHD1_k127_5020087_2 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000001016 179.0
SHD1_k127_5020087_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000001042 99.0
SHD1_k127_5059697_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 1.586e-267 847.0
SHD1_k127_5059697_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 1.862e-209 661.0
SHD1_k127_5059697_2 lyase activity K01667 - 4.1.99.1 1.552e-197 627.0
SHD1_k127_5059697_3 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 434.0
SHD1_k127_5059697_4 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 328.0
SHD1_k127_5059697_5 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
SHD1_k127_5059697_6 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000002488 218.0
SHD1_k127_5059697_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000009682 191.0
SHD1_k127_5059697_8 Part of a membrane complex involved in electron transport - - - 0.000000000000000000000000000000001692 138.0
SHD1_k127_5059697_9 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000002639 119.0
SHD1_k127_5063231_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 519.0
SHD1_k127_5063231_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 373.0
SHD1_k127_5063231_2 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 312.0
SHD1_k127_5063231_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000196 160.0
SHD1_k127_5063231_4 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000000000000001042 151.0
SHD1_k127_5063231_5 - - - - 0.0000000000000000000000000000001887 128.0
SHD1_k127_5065109_0 B3/4 domain K01890 - 6.1.1.20 4.331e-250 795.0
SHD1_k127_5065109_1 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 374.0
SHD1_k127_5065109_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000008231 87.0
SHD1_k127_5065109_3 - - - - 0.0000008307 55.0
SHD1_k127_5069659_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1215.0
SHD1_k127_5087851_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 338.0
SHD1_k127_5087851_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.000000007035 57.0
SHD1_k127_5095497_0 DEAD/H associated K03724 - - 0.0 1721.0
SHD1_k127_5095497_1 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 521.0
SHD1_k127_5095497_2 Replication initiator protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
SHD1_k127_5095497_3 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 363.0
SHD1_k127_5095497_4 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001103 254.0
SHD1_k127_5095497_5 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000008919 243.0
SHD1_k127_5095497_6 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000001667 199.0
SHD1_k127_5095497_7 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000000000000000000000004487 112.0
SHD1_k127_5095856_0 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 1.796e-222 699.0
SHD1_k127_5095856_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 413.0
SHD1_k127_5095856_2 Rhomboid family - - - 0.000316 44.0
SHD1_k127_5118098_0 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 315.0
SHD1_k127_5118098_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 315.0
SHD1_k127_5118098_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 297.0
SHD1_k127_5132060_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 8.39e-209 662.0
SHD1_k127_5132060_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 409.0
SHD1_k127_5132060_11 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000004378 57.0
SHD1_k127_5132060_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 408.0
SHD1_k127_5132060_3 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 339.0
SHD1_k127_5132060_4 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 341.0
SHD1_k127_5132060_5 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 346.0
SHD1_k127_5132060_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001619 275.0
SHD1_k127_5132060_7 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000008423 220.0
SHD1_k127_5132060_8 - - - - 0.00000000000000000000000000000000000000000000000000000003836 204.0
SHD1_k127_5132060_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000001429 197.0
SHD1_k127_5133071_0 - - - - 0.000000000000000000000000000000000000000005964 163.0
SHD1_k127_5133071_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000001082 148.0
SHD1_k127_5133071_2 COGs COG2823 periplasmic or secreted lipoprotein - - - 0.0000000000005495 71.0
SHD1_k127_5133071_3 Universal stress protein family - - - 0.000004398 58.0
SHD1_k127_5138130_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
SHD1_k127_5138130_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000002624 232.0
SHD1_k127_5138130_2 Tetratricopeptide repeat - - - 0.00000000000004479 74.0
SHD1_k127_5138130_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000002068 68.0
SHD1_k127_5149500_0 TonB dependent receptor - - - 2.458e-291 924.0
SHD1_k127_5149500_1 SusD family K21572 - - 0.0000000000000000000000000000000000000000000002162 185.0
SHD1_k127_5149500_2 - - - - 0.0000000004472 65.0
SHD1_k127_5150723_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.945e-233 737.0
SHD1_k127_5150723_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 416.0
SHD1_k127_5150723_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 356.0
SHD1_k127_5150723_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003598 250.0
SHD1_k127_5150723_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000007014 241.0
SHD1_k127_5150723_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002 228.0
SHD1_k127_5150723_6 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000002562 196.0
SHD1_k127_5150723_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000000000002633 200.0
SHD1_k127_5150723_8 PFAM S23 ribosomal protein - - - 0.00000000000000000001865 96.0
SHD1_k127_5160700_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.409e-251 781.0
SHD1_k127_5160700_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 373.0
SHD1_k127_5160700_2 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 294.0
SHD1_k127_5160700_3 - - - - 0.00000000000000000000000000000000000000000004447 170.0
SHD1_k127_5191369_0 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 561.0
SHD1_k127_5191369_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 512.0
SHD1_k127_5191369_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 366.0
SHD1_k127_5191369_3 - - - - 0.0000000000000003164 82.0
SHD1_k127_5191369_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000001191 70.0
SHD1_k127_5191369_5 Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - 0.0000001844 63.0
SHD1_k127_5191369_6 Peptidase family M28 - - - 0.0000003906 55.0
SHD1_k127_5193062_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 521.0
SHD1_k127_5193062_1 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 448.0
SHD1_k127_5193062_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 387.0
SHD1_k127_5193062_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 356.0
SHD1_k127_5193062_4 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000001082 129.0
SHD1_k127_5198681_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002088 254.0
SHD1_k127_5198681_1 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000001766 216.0
SHD1_k127_5198681_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000002118 61.0
SHD1_k127_5210421_0 DALR_2 K01883 - 6.1.1.16 8.694e-208 655.0
SHD1_k127_5210421_1 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 421.0
SHD1_k127_5210421_2 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 310.0
SHD1_k127_5210421_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000001367 98.0
SHD1_k127_5210421_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000005585 83.0
SHD1_k127_5217712_0 Protein of unknown function (DUF1501) - - - 1.705e-196 623.0
SHD1_k127_5217712_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 489.0
SHD1_k127_5217712_2 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 315.0
SHD1_k127_5217712_3 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002218 274.0
SHD1_k127_5246053_0 COG0433 Predicted ATPase K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 330.0
SHD1_k127_5246053_1 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 317.0
SHD1_k127_5246053_2 COGs COG2380 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006042 277.0
SHD1_k127_5246053_3 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000008947 267.0
SHD1_k127_5246053_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000002307 234.0
SHD1_k127_5246053_5 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000003493 137.0
SHD1_k127_5253156_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 550.0
SHD1_k127_5253156_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 313.0
SHD1_k127_5253156_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 289.0
SHD1_k127_5263611_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 390.0
SHD1_k127_5263611_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000002184 164.0
SHD1_k127_5263611_2 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000004197 141.0
SHD1_k127_5266047_0 FtsX-like permease family K02004 - - 6.383e-239 762.0
SHD1_k127_5266047_1 domain protein K13735 - - 0.000000000000005213 85.0
SHD1_k127_5274611_0 Enoyl-(Acyl carrier protein) reductase - - - 1.68e-255 796.0
SHD1_k127_5274611_1 - - - - 0.00000000000000000000000000000000000000000000000000321 188.0
SHD1_k127_5274611_2 Receptor family ligand binding region K01999 - - 0.0003196 46.0
SHD1_k127_5277605_0 alginic acid biosynthetic process - - - 3.332e-229 734.0
SHD1_k127_5277605_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 5.772e-198 626.0
SHD1_k127_5277605_2 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000002728 149.0
SHD1_k127_527769_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
SHD1_k127_527769_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
SHD1_k127_5303329_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 480.0
SHD1_k127_5303329_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000229 281.0
SHD1_k127_5303329_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
SHD1_k127_5303329_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000002446 188.0
SHD1_k127_530385_0 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000001606 210.0
SHD1_k127_530385_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000001704 198.0
SHD1_k127_530385_2 Alpha beta hydrolase fold protein - - - 0.0000000000000000000000000000000236 128.0
SHD1_k127_530385_3 Redoxin - - - 0.000000000000000000000004461 109.0
SHD1_k127_530385_4 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000005198 73.0
SHD1_k127_5312163_0 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 424.0
SHD1_k127_5312163_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 382.0
SHD1_k127_5312163_2 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 364.0
SHD1_k127_5312163_3 - - - - 0.0000000000000000000000000000000000002687 153.0
SHD1_k127_531662_0 DegT/DnrJ/EryC1/StrS aminotransferase family K18653 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009987,GO:0016740,GO:0016769,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 473.0
SHD1_k127_531662_1 Transketolase, thiamine diphosphate binding domain K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 408.0
SHD1_k127_531662_2 Alternative locus ID K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 406.0
SHD1_k127_5321393_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
SHD1_k127_5321393_1 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001875 261.0
SHD1_k127_5322715_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 417.0
SHD1_k127_5327581_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 2.528e-236 736.0
SHD1_k127_5327581_1 MviN-like protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 595.0
SHD1_k127_5327581_2 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 407.0
SHD1_k127_5327581_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004685 242.0
SHD1_k127_5327581_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000007369 201.0
SHD1_k127_5327581_5 SAM-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001493 196.0
SHD1_k127_5347911_0 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 325.0
SHD1_k127_5347911_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000001538 244.0
SHD1_k127_5347911_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000003206 151.0
SHD1_k127_5347911_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000002914 115.0
SHD1_k127_5358016_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 578.0
SHD1_k127_5358016_1 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 311.0
SHD1_k127_5358016_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000001393 86.0
SHD1_k127_5359858_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 592.0
SHD1_k127_5359858_1 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.000000000000000000000000009049 111.0
SHD1_k127_5359858_2 cAMP biosynthetic process - - - 0.0000000000001906 80.0
SHD1_k127_5361221_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 545.0
SHD1_k127_5361221_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000119 149.0
SHD1_k127_5367487_0 Rhodanese Homology Domain K01069,K03797 - 3.1.2.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 586.0
SHD1_k127_5367487_1 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 331.0
SHD1_k127_5367487_2 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 304.0
SHD1_k127_5367487_3 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
SHD1_k127_5367487_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000155 129.0
SHD1_k127_5367487_5 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000009012 114.0
SHD1_k127_5367487_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0004156 47.0
SHD1_k127_5378721_0 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 575.0
SHD1_k127_5378721_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 466.0
SHD1_k127_5378721_3 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.00000000000000000000000000008251 126.0
SHD1_k127_5398504_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 511.0
SHD1_k127_5398504_1 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 486.0
SHD1_k127_5398504_2 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 380.0
SHD1_k127_5398504_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
SHD1_k127_5398504_4 - - - - 0.0000000000000000000006507 101.0
SHD1_k127_5401820_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 493.0
SHD1_k127_5401820_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 391.0
SHD1_k127_5401820_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000001951 236.0
SHD1_k127_5401820_3 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000005412 214.0
SHD1_k127_5401820_4 - - - - 0.0000000000000000000000000000000000000001044 157.0
SHD1_k127_5401820_5 crp fnr family K21564 - - 0.00008953 53.0
SHD1_k127_5422298_0 Putative modulator of DNA gyrase K03568 - - 1.711e-231 726.0
SHD1_k127_5422298_1 nucleotide catabolic process K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 428.0
SHD1_k127_5424281_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.357e-223 707.0
SHD1_k127_5424281_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 483.0
SHD1_k127_5424281_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 286.0
SHD1_k127_5424281_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
SHD1_k127_5433007_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 541.0
SHD1_k127_5433007_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 351.0
SHD1_k127_5433007_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003167 282.0
SHD1_k127_5433007_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000002197 176.0
SHD1_k127_5457458_0 ABC transporter transmembrane region - - - 1.904e-236 745.0
SHD1_k127_5457458_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 443.0
SHD1_k127_5457458_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000001238 105.0
SHD1_k127_5457458_3 Cytochrome oxidase assembly protein K02259 - - 0.00003153 47.0
SHD1_k127_5501557_0 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 427.0
SHD1_k127_5501557_1 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 422.0
SHD1_k127_5501557_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 321.0
SHD1_k127_5501557_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000007654 254.0
SHD1_k127_5501557_4 Peptidase family M48 - - - 0.000000000000000000000000007666 113.0
SHD1_k127_5506001_0 DNA polymerase alpha chain like domain K02347 - - 2.889e-199 636.0
SHD1_k127_5506001_1 - - - - 0.0000000000000000000000000000001134 130.0
SHD1_k127_5506001_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000002931 52.0
SHD1_k127_566500_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 618.0
SHD1_k127_566500_1 Acts as a magnesium transporter K06213 - - 0.0000000002462 61.0
SHD1_k127_566500_2 haemagglutination activity domain - - - 0.0000000002549 70.0
SHD1_k127_566500_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000005288 60.0
SHD1_k127_610141_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 601.0
SHD1_k127_610141_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001046 237.0
SHD1_k127_610141_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000002777 233.0
SHD1_k127_610141_3 - - - - 0.0000000000000001772 88.0
SHD1_k127_615092_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 452.0
SHD1_k127_615092_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 367.0
SHD1_k127_615092_2 Protein export membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 338.0
SHD1_k127_615092_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 327.0
SHD1_k127_615092_4 - - - - 0.0000000000000000000000000000000000162 143.0
SHD1_k127_615092_5 EamA-like transporter family - - - 0.00000000000001006 76.0
SHD1_k127_616694_0 Endoribonuclease that initiates mRNA decay K18682 - - 4.998e-240 751.0
SHD1_k127_616694_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 374.0
SHD1_k127_63266_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.432e-229 728.0
SHD1_k127_63266_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 444.0
SHD1_k127_63266_2 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 370.0
SHD1_k127_63266_3 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000003464 190.0
SHD1_k127_63266_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.0000000000000000000000000000000003079 143.0
SHD1_k127_63266_5 Peptidase family M50 - - - 0.0000000000000000000000003675 108.0
SHD1_k127_63266_6 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000003607 75.0
SHD1_k127_63266_7 FeoA K04758 - - 0.00000000004738 68.0
SHD1_k127_652656_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.04e-298 928.0
SHD1_k127_652656_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 478.0
SHD1_k127_652656_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 349.0
SHD1_k127_677003_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 393.0
SHD1_k127_677003_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003853 254.0
SHD1_k127_677003_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000009057 67.0
SHD1_k127_67823_0 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 337.0
SHD1_k127_67823_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
SHD1_k127_67823_2 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000000003653 203.0
SHD1_k127_67823_3 - - - - 0.0000000000000000000000000001397 122.0
SHD1_k127_67823_4 SWI complex, BAF60b domains - - - 0.00000000005002 63.0
SHD1_k127_705948_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1475.0
SHD1_k127_705948_1 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 502.0
SHD1_k127_705948_10 - - - - 0.00000000000000000000000000000005764 130.0
SHD1_k127_705948_11 Transglycosylase associated protein - - - 0.000000000000000000000000008901 111.0
SHD1_k127_705948_12 Transglycosylase associated protein - - - 0.0000000000000000002326 90.0
SHD1_k127_705948_14 lipoprotein YddW precursor - - - 0.0001619 49.0
SHD1_k127_705948_2 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 358.0
SHD1_k127_705948_3 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 311.0
SHD1_k127_705948_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007255 265.0
SHD1_k127_705948_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000267 258.0
SHD1_k127_705948_6 Regulator of chromosome condensation - - - 0.000000000000000000000000000000000000000000000000000000000000000000472 252.0
SHD1_k127_705948_7 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000004217 238.0
SHD1_k127_705948_8 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000000001031 220.0
SHD1_k127_705948_9 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000000000000001936 179.0
SHD1_k127_710603_0 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
SHD1_k127_710603_1 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 376.0
SHD1_k127_71372_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 585.0
SHD1_k127_71372_2 acr, cog1993 K09137 - - 0.0000000000000000000000000000000000000000001383 163.0
SHD1_k127_71372_3 acr, cog1993 K09137 - - 0.000000000000000000000000000000000001575 141.0
SHD1_k127_71372_4 Capsule assembly protein Wzi - - - 0.0000000000000000000001658 113.0
SHD1_k127_71372_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000005179 67.0
SHD1_k127_717348_0 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 459.0
SHD1_k127_717348_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001723 287.0
SHD1_k127_717348_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000703 263.0
SHD1_k127_717348_3 lipopolysaccharide-transporting ATPase activity K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003725 245.0
SHD1_k127_717348_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000006408 196.0
SHD1_k127_717348_5 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000003004 156.0
SHD1_k127_717348_6 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000005435 124.0
SHD1_k127_717348_7 - - - - 0.00000000000000000009325 89.0
SHD1_k127_717348_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000002391 87.0
SHD1_k127_717348_9 - - - - 0.0002709 51.0
SHD1_k127_718908_0 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 366.0
SHD1_k127_718908_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000007825 253.0
SHD1_k127_718908_2 Domain of unknown function (DUF4118) - - - 0.00005684 55.0
SHD1_k127_722767_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.561e-313 975.0
SHD1_k127_722767_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 3.482e-233 734.0
SHD1_k127_722767_2 GMC oxidoreductase - - - 1.401e-221 692.0
SHD1_k127_722767_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 430.0
SHD1_k127_722767_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
SHD1_k127_722767_5 - K07274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000603 246.0
SHD1_k127_722767_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000007771 207.0
SHD1_k127_722767_7 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000003727 164.0
SHD1_k127_727514_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 396.0
SHD1_k127_727514_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 400.0
SHD1_k127_730236_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1065.0
SHD1_k127_730236_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 1.771e-318 986.0
SHD1_k127_730236_2 Domain of unknown function (DUF5117) - - - 5.402e-255 811.0
SHD1_k127_730236_3 Glycine D-amino acid oxidase (deaminating) - - - 6.007e-199 633.0
SHD1_k127_730236_4 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 480.0
SHD1_k127_730236_5 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 364.0
SHD1_k127_730236_6 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 306.0
SHD1_k127_730236_7 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000003383 237.0
SHD1_k127_730236_8 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000001893 206.0
SHD1_k127_730983_0 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 431.0
SHD1_k127_730983_1 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001538 264.0
SHD1_k127_730983_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000001769 214.0
SHD1_k127_730983_3 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000698 124.0
SHD1_k127_730983_4 OmpA family - - - 0.0000000000000001907 87.0
SHD1_k127_764415_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1188.0
SHD1_k127_764415_1 Amidohydrolase family - - - 2.213e-243 768.0
SHD1_k127_764415_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000001354 162.0
SHD1_k127_764415_3 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000001941 117.0
SHD1_k127_764415_4 Domain of unknown function (DUF4105) - - - 0.0000000000000000000002753 105.0
SHD1_k127_764415_5 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000002365 68.0
SHD1_k127_76736_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 584.0
SHD1_k127_76736_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
SHD1_k127_76736_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
SHD1_k127_76736_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000002627 181.0
SHD1_k127_76736_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000007542 179.0
SHD1_k127_76736_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001192 179.0
SHD1_k127_76736_6 Domain of unknown function (DUF4321) - - - 0.00000000000000000000000000000000005177 135.0
SHD1_k127_76736_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000004806 89.0
SHD1_k127_771134_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 322.0
SHD1_k127_771134_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000001357 207.0
SHD1_k127_771134_2 - - - - 0.00000000000000000000000000002254 119.0
SHD1_k127_771134_3 - - - - 0.00000000000002182 79.0
SHD1_k127_778485_0 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 370.0
SHD1_k127_778485_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000001605 199.0
SHD1_k127_778485_2 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000003819 177.0
SHD1_k127_778485_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000001201 112.0
SHD1_k127_778485_4 - - - - 0.00000000000000000000000001206 115.0
SHD1_k127_778485_5 Domain of unknown function (DUF4412) - - - 0.0000001432 63.0
SHD1_k127_789057_0 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000007044 256.0
SHD1_k127_789057_1 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000003264 177.0
SHD1_k127_789057_2 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000006787 89.0
SHD1_k127_791007_0 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004412 286.0
SHD1_k127_791007_1 Phosphate acyltransferases K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001939 253.0
SHD1_k127_79115_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000008326 74.0
SHD1_k127_793940_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 552.0
SHD1_k127_793940_1 Domain of unknown function (DUF4198) - - - 0.000000000000000000000000000000000000004502 153.0
SHD1_k127_80760_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 5.918e-317 981.0
SHD1_k127_80760_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 386.0
SHD1_k127_80760_2 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
SHD1_k127_80760_3 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
SHD1_k127_80760_4 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000002042 196.0
SHD1_k127_812373_0 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000003575 201.0
SHD1_k127_812373_1 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000002053 151.0
SHD1_k127_812373_2 dolichyl-phosphate beta-glucosyltransferase K00729,K03027 GO:0001667,GO:0001703,GO:0001704,GO:0001707,GO:0003002,GO:0003674,GO:0003824,GO:0004576,GO:0004581,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006486,GO:0006487,GO:0006493,GO:0006807,GO:0006928,GO:0006996,GO:0007009,GO:0007029,GO:0007030,GO:0007043,GO:0007275,GO:0007368,GO:0007369,GO:0007389,GO:0007498,GO:0007509,GO:0008078,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009653,GO:0009790,GO:0009799,GO:0009855,GO:0009888,GO:0009953,GO:0009987,GO:0010004,GO:0010256,GO:0012505,GO:0016020,GO:0016043,GO:0016477,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0019991,GO:0022607,GO:0031984,GO:0032501,GO:0032502,GO:0034329,GO:0034330,GO:0034645,GO:0035251,GO:0036211,GO:0040003,GO:0040011,GO:0042074,GO:0042175,GO:0042335,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043297,GO:0043412,GO:0043413,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045216,GO:0046527,GO:0048332,GO:0048598,GO:0048646,GO:0048729,GO:0048856,GO:0048870,GO:0051179,GO:0051674,GO:0061024,GO:0070085,GO:0071704,GO:0071840,GO:0090130,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.117 0.0006429 45.0
SHD1_k127_814804_0 Peptidase M14, carboxypeptidase A - - - 0.0 1246.0
SHD1_k127_814804_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 589.0
SHD1_k127_814804_2 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 495.0
SHD1_k127_814804_3 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 346.0
SHD1_k127_814804_4 PFAM glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 342.0
SHD1_k127_814804_5 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003347 245.0
SHD1_k127_814804_6 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000003847 192.0
SHD1_k127_814804_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000007332 158.0
SHD1_k127_814804_8 HNH nucleases - - - 0.000000000001505 76.0
SHD1_k127_82473_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 422.0
SHD1_k127_82473_1 - - - - 0.0000000000000000000000000000000000000006388 152.0
SHD1_k127_826272_0 Fumarase C C-terminus K01744 - 4.3.1.1 3.505e-231 725.0
SHD1_k127_826272_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 335.0
SHD1_k127_826272_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 304.0
SHD1_k127_826272_3 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 297.0
SHD1_k127_826272_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002936 258.0
SHD1_k127_826272_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000427 243.0
SHD1_k127_826272_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
SHD1_k127_826272_7 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K15256 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000005377 133.0
SHD1_k127_826272_8 - - - - 0.0007745 42.0
SHD1_k127_828306_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 475.0
SHD1_k127_828306_1 - - - - 0.0000000000000000000000000000000003697 134.0
SHD1_k127_828306_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000006036 145.0
SHD1_k127_833256_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 432.0
SHD1_k127_833256_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 383.0
SHD1_k127_833256_2 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 367.0
SHD1_k127_833256_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 289.0
SHD1_k127_837377_0 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 463.0
SHD1_k127_837377_1 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 456.0
SHD1_k127_837377_2 Aldo Keto reductase K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 373.0
SHD1_k127_837377_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000001035 169.0
SHD1_k127_837377_4 cell redox homeostasis - - - 0.0000000000000000000000000000000000000001583 153.0
SHD1_k127_849159_0 4Fe-4S dicluster domain K00184 - - 2.396e-272 860.0
SHD1_k127_849159_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000584 253.0
SHD1_k127_849159_2 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.000003222 49.0
SHD1_k127_860886_0 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 590.0
SHD1_k127_860886_1 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 297.0
SHD1_k127_860886_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 293.0
SHD1_k127_860886_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000000000000000000000000000000000000000000005436 191.0
SHD1_k127_860886_4 Beta-eliminating lyase K00639 - 2.3.1.29 0.0000000000000000000000001272 107.0
SHD1_k127_860886_5 - - - - 0.00001655 49.0
SHD1_k127_862389_0 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000003309 153.0
SHD1_k127_862389_1 glycosyl transferase family 2 - - - 0.0000000000000000000000000001006 128.0
SHD1_k127_862389_2 oligosaccharyl transferase activity - - - 0.000000000000000443 92.0
SHD1_k127_863258_0 Polysulphide reductase, NrfD K00185 - - 3.088e-257 799.0
SHD1_k127_863258_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 481.0
SHD1_k127_863258_2 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000001015 155.0
SHD1_k127_867578_0 xanthine dehydrogenase activity - - - 0.0 1145.0
SHD1_k127_867578_1 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000005879 245.0
SHD1_k127_867578_2 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000002301 174.0
SHD1_k127_867578_3 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000002412 96.0
SHD1_k127_892053_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 563.0
SHD1_k127_892053_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 407.0
SHD1_k127_89364_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 599.0
SHD1_k127_89364_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 454.0
SHD1_k127_89364_2 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 433.0
SHD1_k127_89364_3 PAS domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001325 270.0
SHD1_k127_89364_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002609 254.0
SHD1_k127_89364_5 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000008355 192.0
SHD1_k127_89364_6 Transmembrane and - - - 0.0000000000000000000000000000001202 143.0
SHD1_k127_89364_7 Domain of unknown function (DUF1736) - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.0000000000000000001785 98.0
SHD1_k127_894048_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 347.0
SHD1_k127_894048_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 323.0
SHD1_k127_894048_2 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004448 245.0
SHD1_k127_901273_0 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 420.0
SHD1_k127_901273_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 409.0
SHD1_k127_901273_2 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000001654 137.0
SHD1_k127_906492_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 5.307e-234 731.0
SHD1_k127_906492_1 NAD synthase K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 565.0
SHD1_k127_906492_2 Yip1 domain - - - 0.000000000000000000000000000000000000000000000002878 178.0
SHD1_k127_910962_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 500.0
SHD1_k127_910962_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
SHD1_k127_910962_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 318.0
SHD1_k127_929075_0 peptidase K01415,K07386 - 3.4.24.71 7.685e-267 834.0
SHD1_k127_929075_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
SHD1_k127_929075_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000001701 201.0
SHD1_k127_929075_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000002787 195.0
SHD1_k127_929075_4 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000008071 140.0
SHD1_k127_929075_5 transferase activity, transferring glycosyl groups K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000003471 103.0
SHD1_k127_929075_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000009103 85.0
SHD1_k127_929075_7 Domain of Unknown function (DUF542) K07322 - - 0.0000000001129 65.0
SHD1_k127_942299_0 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 475.0
SHD1_k127_942299_1 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 379.0
SHD1_k127_942299_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 362.0
SHD1_k127_942299_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000004575 140.0
SHD1_k127_946408_0 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 503.0
SHD1_k127_946408_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
SHD1_k127_946617_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 552.0
SHD1_k127_946617_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 370.0
SHD1_k127_946617_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000149 110.0
SHD1_k127_952174_0 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 418.0
SHD1_k127_952174_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
SHD1_k127_952174_2 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000009378 215.0
SHD1_k127_952174_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000001405 195.0
SHD1_k127_952174_4 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000634 161.0
SHD1_k127_952174_5 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000009786 85.0
SHD1_k127_955466_0 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 488.0
SHD1_k127_955466_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 467.0
SHD1_k127_955466_2 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 304.0
SHD1_k127_955466_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000001666 79.0
SHD1_k127_960197_0 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 603.0
SHD1_k127_960197_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001772 235.0
SHD1_k127_960197_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000004048 69.0
SHD1_k127_960197_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00007344 45.0
SHD1_k127_979313_0 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 341.0
SHD1_k127_979313_1 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 345.0
SHD1_k127_979313_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000151 260.0
SHD1_k127_979313_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.00000000000000000002074 91.0
SHD1_k127_981110_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.0 1026.0
SHD1_k127_981110_1 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 8.798e-249 773.0
SHD1_k127_981110_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 468.0
SHD1_k127_981110_3 Na H antiporter K03315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 449.0
SHD1_k127_981110_4 - - - - 0.000000000000000000000000000000000000000000000003461 180.0
SHD1_k127_981110_5 Leishmanolysin - - - 0.000000000000000000000000000000000000169 162.0
SHD1_k127_981110_6 SnoaL-like polyketide cyclase - - - 0.0000000000000000000001661 102.0
SHD1_k127_981110_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000009715 86.0
SHD1_k127_981110_8 Domain of unknown function (DUF4440) - - - 0.0000000005494 67.0
SHD1_k127_981110_9 Methyltransferase domain - - - 0.000002525 49.0
SHD1_k127_984437_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 490.0
SHD1_k127_984437_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 348.0
SHD1_k127_996021_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0 1487.0
SHD1_k127_996021_1 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 327.0