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Overview

ID MAG03369
Name SHD1_bin.7
Sample SMP0082
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus Sulfobium
Species
Assembly information
Completeness (%) 93.32
Contamination (%) 2.37
GC content (%) 51.0
N50 (bp) 10,082
Genome size (bp) 2,610,945

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2511

Gene name Description KEGG GOs EC E-value Score Sequence
SHD1_k127_1001645_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 555.0
SHD1_k127_1001645_1 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 564.0
SHD1_k127_1001645_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000005615 114.0
SHD1_k127_1001645_11 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000002205 104.0
SHD1_k127_1001645_12 Prokaryotic cytochrome b561 - - - 0.000000000000000001087 93.0
SHD1_k127_1001645_13 Protein of unknown function (DUF2892) - - - 0.000000000006471 72.0
SHD1_k127_1001645_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 559.0
SHD1_k127_1001645_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 494.0
SHD1_k127_1001645_4 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 460.0
SHD1_k127_1001645_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 316.0
SHD1_k127_1001645_6 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
SHD1_k127_1001645_7 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000001477 224.0
SHD1_k127_1001645_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000896 123.0
SHD1_k127_1003998_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 545.0
SHD1_k127_1003998_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 312.0
SHD1_k127_1003998_2 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000001595 219.0
SHD1_k127_1003998_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000001373 171.0
SHD1_k127_1003998_4 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000002723 111.0
SHD1_k127_1003998_5 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000007789 98.0
SHD1_k127_101625_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 615.0
SHD1_k127_101625_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 565.0
SHD1_k127_101625_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005256 275.0
SHD1_k127_101625_11 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004943 275.0
SHD1_k127_101625_12 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003612 263.0
SHD1_k127_101625_13 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001112 262.0
SHD1_k127_101625_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004214 247.0
SHD1_k127_101625_15 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000009864 222.0
SHD1_k127_101625_16 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000004697 170.0
SHD1_k127_101625_17 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000001181 135.0
SHD1_k127_101625_18 Belongs to the UPF0235 family K09131 - - 0.000000000000003262 78.0
SHD1_k127_101625_19 cell division protein FtsQ K03589 - - 0.0000000000008981 78.0
SHD1_k127_101625_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 525.0
SHD1_k127_101625_20 Peptidase family M23 - - - 0.0000000007151 59.0
SHD1_k127_101625_23 Evidence 5 No homology to any previously reported sequences - - - 0.0001933 51.0
SHD1_k127_101625_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 458.0
SHD1_k127_101625_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 419.0
SHD1_k127_101625_5 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 394.0
SHD1_k127_101625_6 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 380.0
SHD1_k127_101625_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 368.0
SHD1_k127_101625_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 358.0
SHD1_k127_101625_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
SHD1_k127_1035362_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 571.0
SHD1_k127_1035362_1 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001143 160.0
SHD1_k127_1035362_2 Belongs to the MEMO1 family K06990 - - 0.0000000000000003463 79.0
SHD1_k127_1035362_3 DsrE/DsrF/DrsH-like family - - - 0.00000000006931 63.0
SHD1_k127_1068908_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 550.0
SHD1_k127_1068908_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 335.0
SHD1_k127_1068908_2 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000001608 184.0
SHD1_k127_1068908_3 Belongs to the universal stress protein A family - - - 0.000025 48.0
SHD1_k127_1084182_0 General secretory system II, protein E domain protein K02652 - - 2.353e-217 691.0
SHD1_k127_1084182_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 546.0
SHD1_k127_1084182_10 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000281 121.0
SHD1_k127_1084182_11 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000003996 114.0
SHD1_k127_1084182_12 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000003097 90.0
SHD1_k127_1084182_2 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 402.0
SHD1_k127_1084182_3 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 378.0
SHD1_k127_1084182_4 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 349.0
SHD1_k127_1084182_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004113 272.0
SHD1_k127_1084182_6 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.0000000000000000000000000000000000000000003012 171.0
SHD1_k127_1084182_7 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000005048 153.0
SHD1_k127_1084182_8 response to copper ion K07156,K14166 - - 0.000000000000000000000000000000005722 132.0
SHD1_k127_1084182_9 NosL - - - 0.0000000000000000000000000000001737 140.0
SHD1_k127_1102331_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 6.648e-247 775.0
SHD1_k127_1102331_1 FAD binding domain K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 625.0
SHD1_k127_1102331_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 591.0
SHD1_k127_1102331_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 472.0
SHD1_k127_1102331_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 475.0
SHD1_k127_1102331_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 267.0
SHD1_k127_1102331_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000002268 195.0
SHD1_k127_1129262_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.296e-263 822.0
SHD1_k127_1129262_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.326e-203 642.0
SHD1_k127_1129262_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 485.0
SHD1_k127_1129262_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 384.0
SHD1_k127_1129262_4 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001941 267.0
SHD1_k127_113378_0 Glycosyl hydrolase family 57 - - - 1.633e-238 758.0
SHD1_k127_113378_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 594.0
SHD1_k127_113378_2 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
SHD1_k127_113378_3 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000001434 206.0
SHD1_k127_113378_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000008516 192.0
SHD1_k127_113378_5 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.000000000000000000000000000000000001571 141.0
SHD1_k127_113378_6 - - - - 0.000000000000000000000000000000003158 145.0
SHD1_k127_113378_7 cell cycle K05589,K12065,K13052 - - 0.000000000000009825 78.0
SHD1_k127_113378_8 Pfam:Cache_1 K03406 - - 0.00001043 49.0
SHD1_k127_1186406_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 594.0
SHD1_k127_1186406_1 ATPase with chaperone activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 420.0
SHD1_k127_1186406_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 374.0
SHD1_k127_1186406_3 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000009772 220.0
SHD1_k127_1188137_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 487.0
SHD1_k127_1188137_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 458.0
SHD1_k127_1188137_2 - - - - 0.000000000000000000000000000000000000000000000000000408 189.0
SHD1_k127_1188137_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000001648 147.0
SHD1_k127_1188137_4 HD domain K07814 - - 0.00000000000000000004835 101.0
SHD1_k127_1216599_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 418.0
SHD1_k127_1216599_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 400.0
SHD1_k127_1216599_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 311.0
SHD1_k127_1216599_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000002395 210.0
SHD1_k127_1216599_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000003499 220.0
SHD1_k127_1216599_5 histidine kinase-, DNA gyrase B - - - 0.00005664 53.0
SHD1_k127_1296682_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 563.0
SHD1_k127_130677_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1202.0
SHD1_k127_130677_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 506.0
SHD1_k127_130677_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001943 266.0
SHD1_k127_130677_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000007656 96.0
SHD1_k127_130677_4 S4 domain K14761 - - 0.000000000000000000004305 94.0
SHD1_k127_130677_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000006532 94.0
SHD1_k127_143087_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 363.0
SHD1_k127_143087_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000001025 199.0
SHD1_k127_143087_2 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000000000000000004659 152.0
SHD1_k127_143087_3 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000002526 155.0
SHD1_k127_143087_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000003268 153.0
SHD1_k127_143087_5 ABC 3 transport family K09816 - - 0.0000000000000001933 83.0
SHD1_k127_143087_7 Resolvase - - - 0.000000382 52.0
SHD1_k127_143087_8 - - - - 0.0000005554 51.0
SHD1_k127_1435626_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 7.728e-219 688.0
SHD1_k127_1435626_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 561.0
SHD1_k127_1435626_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 306.0
SHD1_k127_1435626_11 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 327.0
SHD1_k127_1435626_12 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 288.0
SHD1_k127_1435626_13 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008893 274.0
SHD1_k127_1435626_14 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005743 273.0
SHD1_k127_1435626_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007983 273.0
SHD1_k127_1435626_16 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
SHD1_k127_1435626_17 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000005215 219.0
SHD1_k127_1435626_18 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000004032 186.0
SHD1_k127_1435626_19 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000009215 165.0
SHD1_k127_1435626_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 486.0
SHD1_k127_1435626_20 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000375 136.0
SHD1_k127_1435626_21 thiolester hydrolase activity - - - 0.0000000000000000000000000000136 124.0
SHD1_k127_1435626_22 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000001333 120.0
SHD1_k127_1435626_23 PFAM CheW domain protein K03408 - - 0.000000000000000000001365 103.0
SHD1_k127_1435626_24 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.000000000005319 68.0
SHD1_k127_1435626_25 - - - - 0.00000000001454 72.0
SHD1_k127_1435626_26 transferase activity, transferring glycosyl groups - - - 0.000000001134 65.0
SHD1_k127_1435626_27 - - - - 0.000002733 55.0
SHD1_k127_1435626_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 461.0
SHD1_k127_1435626_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 445.0
SHD1_k127_1435626_5 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 409.0
SHD1_k127_1435626_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 381.0
SHD1_k127_1435626_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 364.0
SHD1_k127_1435626_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 367.0
SHD1_k127_1435626_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 314.0
SHD1_k127_1437456_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 335.0
SHD1_k127_1437456_1 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001515 242.0
SHD1_k127_1437456_2 HNH nucleases - - - 0.0000000000000000000000000000000000131 138.0
SHD1_k127_1437456_3 isomerase activity K01821 - 5.3.2.6 0.0000000000000000000000001572 109.0
SHD1_k127_1437456_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000006835 94.0
SHD1_k127_1437456_5 GAF domain - - - 0.00000000000000009461 94.0
SHD1_k127_1437456_6 PAS fold - - - 0.00000002053 67.0
SHD1_k127_1451328_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000003467 199.0
SHD1_k127_1451328_1 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000006588 150.0
SHD1_k127_1451328_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000004903 123.0
SHD1_k127_1451328_3 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000007515 68.0
SHD1_k127_1462452_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 315.0
SHD1_k127_1462452_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000174 273.0
SHD1_k127_1462452_2 zinc-ribbon domain - - - 0.000000000000000000000000000001398 121.0
SHD1_k127_1462452_3 - - - - 0.000000000000000000000001387 111.0
SHD1_k127_1462452_4 - - - - 0.000000003532 62.0
SHD1_k127_146985_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.273e-319 990.0
SHD1_k127_146985_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 381.0
SHD1_k127_146985_2 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000001798 201.0
SHD1_k127_146985_3 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000001469 106.0
SHD1_k127_146985_4 Integrase K07497 - - 0.00000000000000002673 85.0
SHD1_k127_146985_5 Psort location Cytoplasmic, score - - - 0.000001136 53.0
SHD1_k127_1474868_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 598.0
SHD1_k127_1474868_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 367.0
SHD1_k127_1474868_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 297.0
SHD1_k127_1474868_3 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 284.0
SHD1_k127_1474868_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000007533 239.0
SHD1_k127_1474868_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000005298 127.0
SHD1_k127_1474868_6 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000001278 115.0
SHD1_k127_1474868_7 Sugar-specific transcriptional regulator TrmB - - - 0.0000000004549 63.0
SHD1_k127_1474868_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00004129 48.0
SHD1_k127_1497645_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 593.0
SHD1_k127_1497645_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 392.0
SHD1_k127_1497645_2 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 273.0
SHD1_k127_1497645_3 lactate metabolic process K11473,K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 246.0
SHD1_k127_1499737_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 3.294e-269 854.0
SHD1_k127_1499737_1 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000324 282.0
SHD1_k127_1499737_2 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000005714 224.0
SHD1_k127_1499737_3 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000008203 178.0
SHD1_k127_1499737_4 Predicted RNA-binding protein - - - 0.00000000000000000001973 91.0
SHD1_k127_1499737_5 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.000000005219 69.0
SHD1_k127_1499737_6 helix_turn_helix, Lux Regulon - - - 0.0000001011 60.0
SHD1_k127_1499737_7 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000003954 53.0
SHD1_k127_1499737_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00001269 58.0
SHD1_k127_1499737_9 Tetratricopeptide repeat - - - 0.000471 53.0
SHD1_k127_1511110_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 454.0
SHD1_k127_1511110_1 helix_turn_helix, Lux Regulon K02282,K07689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 291.0
SHD1_k127_1511110_10 Protein of unknown function (DUF2905) - - - 0.00000000000000000006758 93.0
SHD1_k127_1511110_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
SHD1_k127_1511110_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
SHD1_k127_1511110_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
SHD1_k127_1511110_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004244 271.0
SHD1_k127_1511110_6 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000003383 227.0
SHD1_k127_1511110_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000006949 186.0
SHD1_k127_1511110_8 Histidine kinase K07711 - 2.7.13.3 0.000000000000000000000000000000000000000003407 177.0
SHD1_k127_1511110_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000005366 115.0
SHD1_k127_1514830_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 546.0
SHD1_k127_1514830_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 387.0
SHD1_k127_1514830_2 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
SHD1_k127_1514830_3 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000003209 240.0
SHD1_k127_1514830_4 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000001911 226.0
SHD1_k127_1514830_5 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000003388 109.0
SHD1_k127_1514830_6 sulfur carrier activity - - - 0.000000000000000115 82.0
SHD1_k127_1514830_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.0006046 45.0
SHD1_k127_1518195_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 565.0
SHD1_k127_1518195_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 492.0
SHD1_k127_1518195_10 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000003104 116.0
SHD1_k127_1518195_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000115 115.0
SHD1_k127_1518195_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001714 104.0
SHD1_k127_1518195_13 Protein of unknown function (DUF507) - - - 0.000000000000000000000003263 104.0
SHD1_k127_1518195_14 4Fe-4S binding domain - - - 0.000000000000000009756 84.0
SHD1_k127_1518195_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 467.0
SHD1_k127_1518195_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 354.0
SHD1_k127_1518195_4 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005818 253.0
SHD1_k127_1518195_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000007086 225.0
SHD1_k127_1518195_6 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000005136 160.0
SHD1_k127_1518195_7 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000000000002001 151.0
SHD1_k127_1518195_8 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000005576 142.0
SHD1_k127_1518195_9 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000000000001712 140.0
SHD1_k127_1524420_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 459.0
SHD1_k127_1524420_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 333.0
SHD1_k127_1524420_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000001697 231.0
SHD1_k127_1535382_0 Alpha-glucan water dikinase K08244 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009608,GO:0009610,GO:0009620,GO:0009628,GO:0009631,GO:0009941,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0031967,GO:0031975,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050521,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901575 2.7.9.4 1.029e-230 750.0
SHD1_k127_1535382_1 Phosphoglucan, water dikinase K15535 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019200,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046777,GO:0046835,GO:0051752,GO:0071704,GO:1901564,GO:1901575 2.7.9.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 588.0
SHD1_k127_1535382_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001131 281.0
SHD1_k127_1535382_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007448 275.0
SHD1_k127_1535382_4 superoxide reductase activity K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000000002712 214.0
SHD1_k127_1535382_5 Alpha amylase, catalytic domain - - - 0.0000000000000005155 91.0
SHD1_k127_156483_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 400.0
SHD1_k127_156483_1 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 302.0
SHD1_k127_156483_2 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000000000113 187.0
SHD1_k127_156483_3 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000008327 193.0
SHD1_k127_156483_4 Transcriptional regulator - - - 0.0000000000000000000000000000000001022 140.0
SHD1_k127_156483_5 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000001522 86.0
SHD1_k127_156483_6 Protein of unknown function (DUF1059) - - - 0.000001013 52.0
SHD1_k127_1575751_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 6.877e-196 629.0
SHD1_k127_1575751_1 PFAM natural resistance-associated macrophage protein K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 520.0
SHD1_k127_1575751_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 489.0
SHD1_k127_1575751_3 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000147 172.0
SHD1_k127_1575751_4 methyltransferase activity - - - 0.00000000000000000000000000000000000000005113 158.0
SHD1_k127_1575751_6 Response regulator receiver - - - 0.000000000000000000000000004455 115.0
SHD1_k127_1575751_7 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000004153 81.0
SHD1_k127_1575751_8 - - - - 0.00000000000001646 75.0
SHD1_k127_1637905_0 - - - - 0.0000000000000000000000000000000000000004518 160.0
SHD1_k127_1637905_3 PilZ domain - - - 0.00002373 52.0
SHD1_k127_1645679_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1083.0
SHD1_k127_1645679_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 4.768e-307 950.0
SHD1_k127_1645679_10 Positive regulator of sigma(E), RseC MucC K03803 - - 0.0000007424 56.0
SHD1_k127_1645679_11 diguanylate cyclase - - - 0.00000511 51.0
SHD1_k127_1645679_2 Elongation factor G, domain IV K02355 - - 1.373e-296 924.0
SHD1_k127_1645679_3 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 292.0
SHD1_k127_1645679_4 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 280.0
SHD1_k127_1645679_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 253.0
SHD1_k127_1645679_6 Glucose-1-phosphate thymidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000004125 120.0
SHD1_k127_1645679_7 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000001359 98.0
SHD1_k127_1645679_9 - - - - 0.0000000000000009668 79.0
SHD1_k127_1649918_0 PFAM ABC transporter K06158 - - 0.000000000000007338 75.0
SHD1_k127_1649918_1 O COG3187 Heat shock protein - - - 0.000000000003222 76.0
SHD1_k127_1694413_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.057e-203 636.0
SHD1_k127_1694413_1 PFAM Uncharacterised protein family UPF0182 K09118 - - 1.293e-196 644.0
SHD1_k127_1694413_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 595.0
SHD1_k127_1694413_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 598.0
SHD1_k127_1694413_4 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 533.0
SHD1_k127_1694413_5 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 477.0
SHD1_k127_1694413_6 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000001629 141.0
SHD1_k127_1694413_7 Transposase K07483 - - 0.0000000813 59.0
SHD1_k127_1696213_0 ABC-2 type transporter K09690,K09692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
SHD1_k127_1696213_1 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 299.0
SHD1_k127_1696213_2 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000001571 172.0
SHD1_k127_1696213_3 - - - - 0.000000000000002254 84.0
SHD1_k127_1696213_4 Subtilase family - - - 0.000000000004207 72.0
SHD1_k127_1696213_5 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000148 54.0
SHD1_k127_1697225_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1024.0
SHD1_k127_1697225_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 415.0
SHD1_k127_1697225_2 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000007231 224.0
SHD1_k127_1697225_3 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000002665 217.0
SHD1_k127_1697225_4 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000003354 192.0
SHD1_k127_1697225_6 Cysteine-rich small domain K07162 - - 0.0000000000000000624 84.0
SHD1_k127_1697225_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000004921 81.0
SHD1_k127_1718994_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1399.0
SHD1_k127_1718994_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 486.0
SHD1_k127_1718994_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 381.0
SHD1_k127_1718994_3 Outer membrane efflux protein - - - 0.0000000000000000000000004289 107.0
SHD1_k127_1718994_4 cell redox homeostasis - - - 0.00000000000000000000009435 99.0
SHD1_k127_1736062_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1149.0
SHD1_k127_1736062_1 C oxidoreductase subunit A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 422.0
SHD1_k127_1736062_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005171 287.0
SHD1_k127_1736062_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000002418 193.0
SHD1_k127_1736062_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000003948 150.0
SHD1_k127_1736062_5 FHA Domain - - - 0.000000000000000000000000000009507 126.0
SHD1_k127_1736062_6 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000839 93.0
SHD1_k127_1736062_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000099 85.0
SHD1_k127_1736062_8 Cytochrome c - - - 0.0000000000000001079 83.0
SHD1_k127_1736062_9 Protein of unknown function (DUF2844) - - - 0.00000000000000015 82.0
SHD1_k127_1746456_0 type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 552.0
SHD1_k127_1746456_1 metal-dependent phosphohydrolase HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001226 266.0
SHD1_k127_1761375_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 504.0
SHD1_k127_1761375_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 486.0
SHD1_k127_1761375_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 388.0
SHD1_k127_1761375_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008954 282.0
SHD1_k127_1761375_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001985 280.0
SHD1_k127_1761375_5 lyase activity K01387,K03301 - 3.4.24.3 0.00000000000000000000000000000000000000000000000000000000000402 219.0
SHD1_k127_1761375_6 Response regulator receiver - - - 0.00001617 55.0
SHD1_k127_1767368_0 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 329.0
SHD1_k127_1767368_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 304.0
SHD1_k127_1767368_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000123 213.0
SHD1_k127_1767368_3 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000000000001339 173.0
SHD1_k127_1767368_4 nucleic-acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000002614 130.0
SHD1_k127_1767368_5 SpoVT / AbrB like domain - - - 0.00000000000000000005697 91.0
SHD1_k127_17769_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 1.87e-266 847.0
SHD1_k127_17769_1 PFAM Type II secretion system protein E K02454 - - 1.475e-199 633.0
SHD1_k127_17769_2 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 528.0
SHD1_k127_17769_3 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 300.0
SHD1_k127_17769_4 protein transport across the cell outer membrane K02452,K02463 - - 0.00000000000000000000000000000000000007281 153.0
SHD1_k127_179939_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002482 262.0
SHD1_k127_179939_1 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000002535 233.0
SHD1_k127_179939_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000001836 194.0
SHD1_k127_179939_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000004202 59.0
SHD1_k127_179939_4 Tetratricopeptide repeat K07452 - - 0.000000008808 65.0
SHD1_k127_1813035_0 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 398.0
SHD1_k127_1813035_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 323.0
SHD1_k127_1813035_2 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 284.0
SHD1_k127_1813035_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000006744 239.0
SHD1_k127_1813035_4 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000001571 141.0
SHD1_k127_1826798_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.12e-202 640.0
SHD1_k127_1826798_1 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
SHD1_k127_1826798_2 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 376.0
SHD1_k127_1826798_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 370.0
SHD1_k127_1826798_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 288.0
SHD1_k127_1829784_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 411.0
SHD1_k127_1829784_1 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000003307 230.0
SHD1_k127_1829784_2 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000002802 128.0
SHD1_k127_1829784_3 Belongs to the 'phage' integrase family - - - 0.0000000000000001829 83.0
SHD1_k127_1840637_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1056.0
SHD1_k127_1840637_1 COG0058 Glucan phosphorylase - - - 7.817e-259 808.0
SHD1_k127_1840637_10 RDD family - - - 0.0000000000000000000000003998 109.0
SHD1_k127_1840637_11 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000002957 103.0
SHD1_k127_1840637_12 exodeoxyribonuclease I activity - - - 0.00000000000005541 75.0
SHD1_k127_1840637_13 - - - - 0.000000004011 59.0
SHD1_k127_1840637_14 Actin K03569 - - 0.00000006228 54.0
SHD1_k127_1840637_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
SHD1_k127_1840637_3 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 410.0
SHD1_k127_1840637_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004374 271.0
SHD1_k127_1840637_5 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
SHD1_k127_1840637_6 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000003698 229.0
SHD1_k127_1840637_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000001451 172.0
SHD1_k127_1840637_8 translation release factor activity - - - 0.0000000000000000000000000000000000000001261 154.0
SHD1_k127_1840637_9 1,4-alpha-glucan branching enzyme activity - - - 0.000000000000000000000000000001772 126.0
SHD1_k127_1845062_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 311.0
SHD1_k127_1845062_1 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007967 259.0
SHD1_k127_1845062_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001058 243.0
SHD1_k127_1845062_3 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000013 142.0
SHD1_k127_1845062_4 - - - - 0.0000000000000000000000421 107.0
SHD1_k127_1851497_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.206e-199 634.0
SHD1_k127_1851497_1 PFAM nickel-dependent hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 596.0
SHD1_k127_1851497_10 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 354.0
SHD1_k127_1851497_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 292.0
SHD1_k127_1851497_12 Calcineurin-like phosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000003595 226.0
SHD1_k127_1851497_13 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000003202 168.0
SHD1_k127_1851497_14 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000002348 108.0
SHD1_k127_1851497_15 cheY-homologous receiver domain - - - 0.000000000000003545 85.0
SHD1_k127_1851497_17 Transglycosylase associated protein - - - 0.00000004086 57.0
SHD1_k127_1851497_2 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 568.0
SHD1_k127_1851497_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 464.0
SHD1_k127_1851497_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 452.0
SHD1_k127_1851497_5 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 406.0
SHD1_k127_1851497_6 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 394.0
SHD1_k127_1851497_7 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 373.0
SHD1_k127_1851497_8 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 361.0
SHD1_k127_1851497_9 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
SHD1_k127_1881572_0 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 433.0
SHD1_k127_1881572_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 404.0
SHD1_k127_1881572_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 288.0
SHD1_k127_1881572_3 metal-dependent phosphohydrolase HD - - - 0.00000000000001066 76.0
SHD1_k127_1881572_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000005985 74.0
SHD1_k127_1881572_5 redox protein regulator of disulfide bond formation K07397 - - 0.0006317 43.0
SHD1_k127_1881745_0 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 442.0
SHD1_k127_1881745_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 328.0
SHD1_k127_1881745_2 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000001746 207.0
SHD1_k127_1881745_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000001014 136.0
SHD1_k127_1881745_4 Protein of unknown function (DUF1264) - - - 0.000000000000007212 81.0
SHD1_k127_1881745_5 Protein of unknown function, DUF255 K06888 - - 0.0001077 50.0
SHD1_k127_1885652_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 575.0
SHD1_k127_1885652_1 Protein of unknown function (DUF3443) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 419.0
SHD1_k127_1885652_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000003713 168.0
SHD1_k127_1885652_3 PFAM Cold-shock protein DNA-binding K03704 - - 0.000000000000000000000005153 104.0
SHD1_k127_1885652_4 Protein of unknown function (DUF2844) - - - 0.00000000000006619 72.0
SHD1_k127_1885652_5 - - - - 0.0000000000003655 72.0
SHD1_k127_1922254_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1103.0
SHD1_k127_1922254_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000003207 81.0
SHD1_k127_1950297_0 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 299.0
SHD1_k127_1950297_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000002012 232.0
SHD1_k127_1950297_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000003664 89.0
SHD1_k127_1972166_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.651e-203 637.0
SHD1_k127_1972166_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 499.0
SHD1_k127_1972166_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 416.0
SHD1_k127_1972166_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 355.0
SHD1_k127_1972166_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 329.0
SHD1_k127_1972166_5 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
SHD1_k127_1972166_6 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 313.0
SHD1_k127_2080688_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 544.0
SHD1_k127_2080688_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000004028 225.0
SHD1_k127_2080688_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000003992 225.0
SHD1_k127_2080688_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0006879 45.0
SHD1_k127_2083526_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.077e-321 994.0
SHD1_k127_2083526_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.789e-268 845.0
SHD1_k127_2083526_10 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 377.0
SHD1_k127_2083526_11 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 370.0
SHD1_k127_2083526_12 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 338.0
SHD1_k127_2083526_13 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 326.0
SHD1_k127_2083526_14 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
SHD1_k127_2083526_15 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 257.0
SHD1_k127_2083526_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001122 272.0
SHD1_k127_2083526_17 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000004806 238.0
SHD1_k127_2083526_18 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000008623 221.0
SHD1_k127_2083526_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000001199 215.0
SHD1_k127_2083526_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 3.533e-257 799.0
SHD1_k127_2083526_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.00000000000000000000000000000000000000000000000000002044 194.0
SHD1_k127_2083526_21 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000003673 188.0
SHD1_k127_2083526_22 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0000000000000000000000000000000000000000001105 170.0
SHD1_k127_2083526_23 response regulator - - - 0.0000000000000000000000000000000000009523 147.0
SHD1_k127_2083526_24 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000002024 140.0
SHD1_k127_2083526_25 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000002071 114.0
SHD1_k127_2083526_27 peptidyl-tyrosine sulfation - - - 0.0004021 47.0
SHD1_k127_2083526_3 NADH dehydrogenase - - - 4.188e-227 719.0
SHD1_k127_2083526_4 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 3.3e-223 715.0
SHD1_k127_2083526_5 cell redox homeostasis - - - 1.013e-209 665.0
SHD1_k127_2083526_6 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 605.0
SHD1_k127_2083526_7 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 601.0
SHD1_k127_2083526_8 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 490.0
SHD1_k127_2083526_9 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 437.0
SHD1_k127_210939_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 529.0
SHD1_k127_210939_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 448.0
SHD1_k127_210939_10 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000006399 216.0
SHD1_k127_210939_11 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000001785 112.0
SHD1_k127_210939_12 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000002508 77.0
SHD1_k127_210939_13 heat shock protein binding K03686 - - 0.0000000002635 73.0
SHD1_k127_210939_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 445.0
SHD1_k127_210939_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 401.0
SHD1_k127_210939_4 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 388.0
SHD1_k127_210939_5 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 342.0
SHD1_k127_210939_6 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 325.0
SHD1_k127_210939_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007222 276.0
SHD1_k127_210939_8 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002373 272.0
SHD1_k127_210939_9 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000039 223.0
SHD1_k127_2117051_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 596.0
SHD1_k127_2117051_1 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 472.0
SHD1_k127_2117051_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 417.0
SHD1_k127_2117051_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 321.0
SHD1_k127_2117051_4 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002901 263.0
SHD1_k127_2117051_5 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000864 214.0
SHD1_k127_2117051_6 Glycosyltransferase like family 2 K12992 - - 0.0000000000000000000000000000000000000002156 155.0
SHD1_k127_2117051_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000003385 61.0
SHD1_k127_21290_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 550.0
SHD1_k127_21290_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 331.0
SHD1_k127_21290_10 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0004293 44.0
SHD1_k127_21290_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 325.0
SHD1_k127_21290_3 ABC transporter K06020 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 310.0
SHD1_k127_21290_4 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
SHD1_k127_21290_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000001423 198.0
SHD1_k127_21290_6 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000000000000000000000000000000000000001269 184.0
SHD1_k127_21290_7 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 - - 0.000000000000000000000000000000008445 128.0
SHD1_k127_21290_8 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000002686 94.0
SHD1_k127_21290_9 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000005256 91.0
SHD1_k127_2130095_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 330.0
SHD1_k127_2130095_1 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000006723 237.0
SHD1_k127_2130095_2 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000002218 226.0
SHD1_k127_2130095_3 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000008521 180.0
SHD1_k127_2130095_4 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000004822 181.0
SHD1_k127_2130095_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000002802 134.0
SHD1_k127_2130095_6 DRTGG domain - - - 0.0000000000000000000000000001096 117.0
SHD1_k127_2133146_0 Surface antigen K07277 - - 2.178e-261 827.0
SHD1_k127_2133146_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 388.0
SHD1_k127_2133146_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 364.0
SHD1_k127_2133146_3 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000001728 220.0
SHD1_k127_2133146_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000004117 205.0
SHD1_k127_2133146_5 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000003143 79.0
SHD1_k127_2133146_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00002388 49.0
SHD1_k127_2181406_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 380.0
SHD1_k127_2181406_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
SHD1_k127_2181406_10 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00006526 55.0
SHD1_k127_2181406_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 320.0
SHD1_k127_2181406_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 293.0
SHD1_k127_2181406_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000004572 231.0
SHD1_k127_2181406_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000002179 158.0
SHD1_k127_2181406_6 NlpC/P60 family K20742 - 3.4.14.13 0.000000000000000000000000000000000006999 149.0
SHD1_k127_2181406_7 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000005274 133.0
SHD1_k127_2181406_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000315 124.0
SHD1_k127_2181406_9 ACT domain protein - - - 0.00000000005688 68.0
SHD1_k127_2189131_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
SHD1_k127_2189131_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000007597 251.0
SHD1_k127_2189131_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000004061 125.0
SHD1_k127_2189131_3 Protein of unknown function (DUF3309) - - - 0.0000000000000000002654 89.0
SHD1_k127_2189131_4 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000007929 75.0
SHD1_k127_2205055_0 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
SHD1_k127_2205055_1 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
SHD1_k127_2205055_2 - - - - 0.000000000000000000004512 99.0
SHD1_k127_2205055_3 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000003232 69.0
SHD1_k127_2205055_4 Haloacid dehalogenase domain protein hydrolase - - - 0.000000007456 57.0
SHD1_k127_2215754_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 591.0
SHD1_k127_2215754_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 577.0
SHD1_k127_2215754_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 510.0
SHD1_k127_2215754_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 429.0
SHD1_k127_2215754_4 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
SHD1_k127_2215754_5 glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
SHD1_k127_2215754_6 Uncharacterized conserved protein (DUF2304) - - - 0.00000000000000000007335 93.0
SHD1_k127_2215754_7 Protein of unknown function DUF86 - - - 0.000000006939 58.0
SHD1_k127_2215754_8 Trypsin-like peptidase domain - - - 0.000007113 58.0
SHD1_k127_222375_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 477.0
SHD1_k127_222375_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 416.0
SHD1_k127_222375_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 374.0
SHD1_k127_222375_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000976 231.0
SHD1_k127_222375_4 O-methyltransferase family 3 - - - 0.0000000000000000000000000000000000000000000000000000000001699 211.0
SHD1_k127_222375_5 Signal transduction response regulator, receiver domain - - - 0.0000000000000000000000000000000000000000000000000001618 194.0
SHD1_k127_222375_6 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000001073 168.0
SHD1_k127_222375_7 Two component regulator propeller - - - 0.000000000000000000000396 106.0
SHD1_k127_222990_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.245e-211 668.0
SHD1_k127_222990_1 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000502 120.0
SHD1_k127_222990_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000001794 113.0
SHD1_k127_222990_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000001028 98.0
SHD1_k127_222990_4 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00003134 48.0
SHD1_k127_222990_5 Phage integrase, N-terminal SAM-like domain - - - 0.0002643 43.0
SHD1_k127_2252149_0 membrane transporter protein K07090 - - 1.116e-202 638.0
SHD1_k127_2252149_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
SHD1_k127_2258519_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 577.0
SHD1_k127_2258519_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 554.0
SHD1_k127_2258519_2 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 434.0
SHD1_k127_2258519_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
SHD1_k127_2270577_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1251.0
SHD1_k127_2270577_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.697e-214 671.0
SHD1_k127_2270577_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000001798 117.0
SHD1_k127_2270577_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003027 103.0
SHD1_k127_2270577_12 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000002749 96.0
SHD1_k127_2270577_13 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000149 72.0
SHD1_k127_2270577_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000000000002236 72.0
SHD1_k127_2270577_15 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000002579 67.0
SHD1_k127_2270577_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 494.0
SHD1_k127_2270577_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 374.0
SHD1_k127_2270577_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 328.0
SHD1_k127_2270577_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006181 259.0
SHD1_k127_2270577_6 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000001598 198.0
SHD1_k127_2270577_7 membrane K00389 - - 0.0000000000000000000000000000000000000000009925 161.0
SHD1_k127_2270577_8 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000001671 149.0
SHD1_k127_2270577_9 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000008491 128.0
SHD1_k127_2293301_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 464.0
SHD1_k127_2293301_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 356.0
SHD1_k127_2293301_2 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 322.0
SHD1_k127_2293301_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
SHD1_k127_2293301_4 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000003561 217.0
SHD1_k127_2293301_5 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000002354 183.0
SHD1_k127_2293301_6 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000003982 179.0
SHD1_k127_2293301_7 TraB family K09973 - - 0.0000000000000000000000000000000000000000008916 165.0
SHD1_k127_2297935_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000008419 257.0
SHD1_k127_2297935_1 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001651 206.0
SHD1_k127_2297935_2 Cytochrome c K08738 - - 0.000000000000000000000004509 106.0
SHD1_k127_2297935_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000006554 65.0
SHD1_k127_2297935_4 Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase - GO:0001505,GO:0001507,GO:0001941,GO:0003674,GO:0005198,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005605,GO:0005615,GO:0005623,GO:0005886,GO:0006581,GO:0006807,GO:0007154,GO:0007267,GO:0007268,GO:0007271,GO:0007528,GO:0008104,GO:0008150,GO:0008152,GO:0008201,GO:0008291,GO:0008582,GO:0009056,GO:0009987,GO:0010817,GO:0016020,GO:0016043,GO:0017144,GO:0023052,GO:0030054,GO:0031012,GO:0031594,GO:0033036,GO:0034613,GO:0040008,GO:0042133,GO:0042135,GO:0042445,GO:0042447,GO:0042737,GO:0043113,GO:0043167,GO:0043168,GO:0044087,GO:0044237,GO:0044248,GO:0044420,GO:0044421,GO:0044464,GO:0045184,GO:0045202,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0051128,GO:0051179,GO:0051234,GO:0051239,GO:0051641,GO:0051668,GO:0051960,GO:0051963,GO:0061024,GO:0062023,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097164,GO:0097367,GO:0098916,GO:0099173,GO:0099536,GO:0099537,GO:1900619,GO:1901575,GO:1901681,GO:1904396,GO:2000026 - 0.00008006 54.0
SHD1_k127_2297983_0 PFAM Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 432.0
SHD1_k127_2297983_1 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000003389 115.0
SHD1_k127_2297983_2 Universal stress protein family - - - 0.00000000003119 71.0
SHD1_k127_2297983_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000001395 58.0
SHD1_k127_2314314_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 483.0
SHD1_k127_2314314_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 395.0
SHD1_k127_2314314_10 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000001698 91.0
SHD1_k127_2314314_12 - - - - 0.000000001617 61.0
SHD1_k127_2314314_2 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 391.0
SHD1_k127_2314314_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 349.0
SHD1_k127_2314314_4 transferase activity, transferring glycosyl groups K00745,K12988,K18704 - 2.4.1.166,2.7.8.14,2.7.8.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 312.0
SHD1_k127_2314314_5 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000977 280.0
SHD1_k127_2314314_6 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000173 232.0
SHD1_k127_2314314_7 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001441 231.0
SHD1_k127_2314314_8 peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000003217 147.0
SHD1_k127_2314314_9 Tetratricopeptide repeat - - - 0.000000000000000005125 93.0
SHD1_k127_233866_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 383.0
SHD1_k127_233866_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 317.0
SHD1_k127_233866_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003938 285.0
SHD1_k127_234789_0 PFAM Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 499.0
SHD1_k127_234789_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 388.0
SHD1_k127_234789_2 - - - - 0.00000000000000000000000000000000000000000000000000000009493 199.0
SHD1_k127_234789_3 Domain of unknown function DUF302 - - - 0.000000000000000472 83.0
SHD1_k127_2377260_0 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002674 242.0
SHD1_k127_2377260_1 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000009883 209.0
SHD1_k127_2377260_2 AMP binding K03499,K06149 - - 0.0000000000000000000000000000000000004194 144.0
SHD1_k127_2377260_3 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.0000002656 63.0
SHD1_k127_2380464_0 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
SHD1_k127_2380464_1 - - - - 0.00000000000000000000001009 111.0
SHD1_k127_2380464_10 Type II secretion system (T2SS), protein J K02459 - - 0.0003157 46.0
SHD1_k127_2380464_2 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000001172 104.0
SHD1_k127_2380464_3 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000008844 79.0
SHD1_k127_2380464_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000001145 79.0
SHD1_k127_2380464_5 Prokaryotic N-terminal methylation motif K02458 - - 0.000000001462 64.0
SHD1_k127_2380464_7 Type II secretion system (T2SS), protein K K02460 - - 0.00000003717 64.0
SHD1_k127_2380464_8 PFAM Phosphate-selective porin O and P - - - 0.00001774 47.0
SHD1_k127_2383219_0 nucleotide-excision repair K03701 - - 1.84e-261 833.0
SHD1_k127_2383219_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 1.82e-217 687.0
SHD1_k127_2383219_10 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 284.0
SHD1_k127_2383219_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 260.0
SHD1_k127_2383219_12 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000003496 201.0
SHD1_k127_2383219_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000005054 200.0
SHD1_k127_2383219_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000008014 151.0
SHD1_k127_2383219_15 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000003241 125.0
SHD1_k127_2383219_16 phosphorelay signal transduction system - - - 0.0000000000000000000000000000267 121.0
SHD1_k127_2383219_17 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000005109 87.0
SHD1_k127_2383219_18 4Fe-4S binding domain - - - 0.000000000000001234 78.0
SHD1_k127_2383219_19 Cupin domain - - - 0.000000006279 61.0
SHD1_k127_2383219_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 573.0
SHD1_k127_2383219_3 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 542.0
SHD1_k127_2383219_4 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 537.0
SHD1_k127_2383219_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 507.0
SHD1_k127_2383219_6 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 411.0
SHD1_k127_2383219_7 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 388.0
SHD1_k127_2383219_8 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 377.0
SHD1_k127_2383219_9 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 343.0
SHD1_k127_2396641_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1301.0
SHD1_k127_2396641_1 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1212.0
SHD1_k127_2396641_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 499.0
SHD1_k127_2396641_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
SHD1_k127_2396641_12 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066,K02472,K02474,K13015 - 1.1.1.132,1.1.1.136,1.1.1.22,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 467.0
SHD1_k127_2396641_13 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 448.0
SHD1_k127_2396641_14 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 422.0
SHD1_k127_2396641_15 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 398.0
SHD1_k127_2396641_16 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 404.0
SHD1_k127_2396641_17 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 397.0
SHD1_k127_2396641_18 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 385.0
SHD1_k127_2396641_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 342.0
SHD1_k127_2396641_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K13378 - 1.6.5.3 9.433e-307 947.0
SHD1_k127_2396641_20 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 340.0
SHD1_k127_2396641_21 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 340.0
SHD1_k127_2396641_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 312.0
SHD1_k127_2396641_23 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 320.0
SHD1_k127_2396641_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 313.0
SHD1_k127_2396641_25 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 293.0
SHD1_k127_2396641_26 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
SHD1_k127_2396641_27 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001761 214.0
SHD1_k127_2396641_28 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001057 189.0
SHD1_k127_2396641_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000000229 164.0
SHD1_k127_2396641_3 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 7.337e-275 864.0
SHD1_k127_2396641_30 Universal stress protein family - - - 0.0000000000000000000000000000000000000000001356 164.0
SHD1_k127_2396641_31 Universal stress protein family - - - 0.00000000000000000000000000000000000000001695 157.0
SHD1_k127_2396641_32 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000001552 137.0
SHD1_k127_2396641_33 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000774 136.0
SHD1_k127_2396641_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000001259 140.0
SHD1_k127_2396641_35 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000004236 124.0
SHD1_k127_2396641_36 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000387 105.0
SHD1_k127_2396641_37 PilZ domain - - - 0.0000000000000000000004217 105.0
SHD1_k127_2396641_38 - - - - 0.000000000000000000001109 98.0
SHD1_k127_2396641_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000009227 93.0
SHD1_k127_2396641_4 ABC transporter K06158 - - 1.146e-240 758.0
SHD1_k127_2396641_40 FecR protein - - - 0.00000000000000000519 93.0
SHD1_k127_2396641_41 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000000002005 80.0
SHD1_k127_2396641_42 O COG3187 Heat shock protein - - - 0.000000000003837 69.0
SHD1_k127_2396641_43 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000009817 73.0
SHD1_k127_2396641_44 Tetratricopeptide repeat - - - 0.000000004012 69.0
SHD1_k127_2396641_46 PKD domain - - - 0.0001562 54.0
SHD1_k127_2396641_5 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 5.802e-236 751.0
SHD1_k127_2396641_6 Endoribonuclease that initiates mRNA decay K18682 - - 1.516e-208 664.0
SHD1_k127_2396641_7 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 2.511e-207 652.0
SHD1_k127_2396641_8 Proton-conducting membrane transporter K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 1.247e-198 634.0
SHD1_k127_2396641_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 609.0
SHD1_k127_2402276_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.63e-207 666.0
SHD1_k127_2402276_10 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000002622 102.0
SHD1_k127_2402276_12 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.00000000000001208 80.0
SHD1_k127_2402276_13 - - - - 0.000000005254 61.0
SHD1_k127_2402276_14 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000001363 59.0
SHD1_k127_2402276_15 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000003119 59.0
SHD1_k127_2402276_2 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 496.0
SHD1_k127_2402276_3 Pyruvate phosphate dikinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
SHD1_k127_2402276_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000002545 253.0
SHD1_k127_2402276_5 AMP binding - - - 0.0000000000000000000000000000000000000000000000000002022 196.0
SHD1_k127_2402276_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000003893 163.0
SHD1_k127_2402276_7 YceI-like domain - - - 0.0000000000000000000000000000000000000003521 156.0
SHD1_k127_2402276_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000006486 138.0
SHD1_k127_2402276_9 protein complex oligomerization - - - 0.00000000000000000000001127 106.0
SHD1_k127_2402858_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 429.0
SHD1_k127_2402858_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 375.0
SHD1_k127_2402858_2 nucleoside hydrolase - - - 0.00000000000000000000000000000000000000001756 176.0
SHD1_k127_2402858_3 - - - - 0.0000000000000000000000000000000349 131.0
SHD1_k127_2402858_4 Lactonase, 7-bladed beta-propeller - - - 0.000000002101 71.0
SHD1_k127_2413648_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.227e-246 769.0
SHD1_k127_2413648_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.224e-237 752.0
SHD1_k127_2413648_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.065e-229 718.0
SHD1_k127_2413648_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 387.0
SHD1_k127_2413648_4 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 312.0
SHD1_k127_2413648_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000006425 133.0
SHD1_k127_2413648_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000001106 95.0
SHD1_k127_2413648_7 zinc-ribbon domain - - - 0.000000001176 61.0
SHD1_k127_2413648_8 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00005571 47.0
SHD1_k127_2421738_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 327.0
SHD1_k127_2421738_1 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000009183 224.0
SHD1_k127_2421738_2 part of a sulfur-relay system K11179 - - 0.00000000000000000000000002072 111.0
SHD1_k127_2421738_3 GTP binding K06944 - - 0.00000000000000000000003934 102.0
SHD1_k127_2438379_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 442.0
SHD1_k127_2438379_1 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 413.0
SHD1_k127_2438379_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 340.0
SHD1_k127_2468545_0 SMART Elongator protein 3 MiaB NifB - - - 7.482e-216 679.0
SHD1_k127_2468545_1 Sulphur transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 437.0
SHD1_k127_2468545_10 Universal stress protein family - - - 0.000000000002311 73.0
SHD1_k127_2468545_11 - - - - 0.000004884 52.0
SHD1_k127_2468545_12 - - - - 0.000008726 53.0
SHD1_k127_2468545_2 PFAM Radical SAM K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 415.0
SHD1_k127_2468545_3 SEFIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 408.0
SHD1_k127_2468545_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 359.0
SHD1_k127_2468545_6 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 347.0
SHD1_k127_2468545_7 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
SHD1_k127_2468545_8 SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 322.0
SHD1_k127_2468545_9 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000008355 102.0
SHD1_k127_2476112_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 346.0
SHD1_k127_2476112_1 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000002417 198.0
SHD1_k127_2476112_2 Putative endonuclease, protein of unknown function (DUF1780) - - - 0.0000000000000000005722 94.0
SHD1_k127_2476112_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000001849 77.0
SHD1_k127_2501921_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 3.306e-202 636.0
SHD1_k127_2501921_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
SHD1_k127_2501921_10 Polysaccharide deacetylase - - - 0.0000000000000000000000000003838 119.0
SHD1_k127_2501921_11 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000001332 94.0
SHD1_k127_2501921_12 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000006367 93.0
SHD1_k127_2501921_13 - - - - 0.0000000000000001374 82.0
SHD1_k127_2501921_14 acetyltransferase - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000007952 49.0
SHD1_k127_2501921_15 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0009807 51.0
SHD1_k127_2501921_2 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 396.0
SHD1_k127_2501921_3 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 386.0
SHD1_k127_2501921_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 366.0
SHD1_k127_2501921_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 294.0
SHD1_k127_2501921_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
SHD1_k127_2501921_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000001829 164.0
SHD1_k127_2501921_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000006242 141.0
SHD1_k127_2501921_9 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000001443 134.0
SHD1_k127_251517_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 561.0
SHD1_k127_251517_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002444 246.0
SHD1_k127_251517_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
SHD1_k127_251517_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
SHD1_k127_251517_4 - - - - 0.0000000000000000000000000000000004247 134.0
SHD1_k127_2537141_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 431.0
SHD1_k127_2537141_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 419.0
SHD1_k127_2537141_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 390.0
SHD1_k127_2537141_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
SHD1_k127_2537141_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000006275 156.0
SHD1_k127_2537141_5 prohibitin homologues - - - 0.000000000000000000001453 95.0
SHD1_k127_2537141_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000009463 92.0
SHD1_k127_2545384_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 542.0
SHD1_k127_2545384_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 366.0
SHD1_k127_2545384_2 oligosaccharyl transferase activity - - - 0.0000000036 62.0
SHD1_k127_2545384_3 SurA N-terminal domain K03771 - 5.2.1.8 0.00001293 55.0
SHD1_k127_2606442_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 439.0
SHD1_k127_2606442_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 338.0
SHD1_k127_2606442_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 301.0
SHD1_k127_2606442_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000004817 180.0
SHD1_k127_2606442_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000267 62.0
SHD1_k127_2640517_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1064.0
SHD1_k127_2640517_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.489e-211 666.0
SHD1_k127_2640517_2 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 518.0
SHD1_k127_2640517_3 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 481.0
SHD1_k127_2640517_4 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 298.0
SHD1_k127_2640517_5 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003748 260.0
SHD1_k127_2640517_6 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
SHD1_k127_2640517_7 radical SAM K06871 - - 0.0000000000000000000000000000000000000000001009 172.0
SHD1_k127_2640517_9 TraB family K09973 - - 0.0000000002624 66.0
SHD1_k127_2647145_0 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 5.142e-251 791.0
SHD1_k127_2647145_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 561.0
SHD1_k127_2656763_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 370.0
SHD1_k127_2656763_1 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 344.0
SHD1_k127_2656763_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.000000000001182 70.0
SHD1_k127_2656763_11 Kazal type serine protease inhibitors - - - 0.00001949 49.0
SHD1_k127_2656763_2 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 347.0
SHD1_k127_2656763_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 341.0
SHD1_k127_2656763_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 296.0
SHD1_k127_2656763_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000002319 258.0
SHD1_k127_2656763_6 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000002605 190.0
SHD1_k127_2656763_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000231 136.0
SHD1_k127_2656763_8 - - - - 0.000000000000000000000002737 105.0
SHD1_k127_2656763_9 toxin-antitoxin pair type II binding - - - 0.000000000000000000001226 97.0
SHD1_k127_2671056_0 DHHA2 domain K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 458.0
SHD1_k127_2671056_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006884 280.0
SHD1_k127_2671056_2 - - - - 0.0000000000000000000000003277 105.0
SHD1_k127_2682901_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.969e-243 762.0
SHD1_k127_2682901_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 333.0
SHD1_k127_2682901_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000003745 98.0
SHD1_k127_2682901_3 - - - - 0.000000000000000000004668 96.0
SHD1_k127_2776935_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 4.082e-225 704.0
SHD1_k127_2776935_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000433 245.0
SHD1_k127_2776935_2 ATP cone domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009758 243.0
SHD1_k127_2776935_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000001583 198.0
SHD1_k127_2776935_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.000000000000000000000000000000000000000000001442 171.0
SHD1_k127_2776935_5 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000673 148.0
SHD1_k127_2776935_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.00000000000000000000000000000007349 131.0
SHD1_k127_2776935_7 - - - - 0.0000000000000000000000000004854 119.0
SHD1_k127_2776935_8 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000005606 109.0
SHD1_k127_2782250_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.416e-271 850.0
SHD1_k127_2782250_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 4.402e-202 643.0
SHD1_k127_2782250_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 291.0
SHD1_k127_2782250_3 Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000001814 105.0
SHD1_k127_2794524_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 583.0
SHD1_k127_2794524_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 422.0
SHD1_k127_2794524_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 369.0
SHD1_k127_2794524_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 254.0
SHD1_k127_2794524_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
SHD1_k127_2794524_5 Belongs to the phospholipase D family. Cardiolipin synthase subfamily K06131 - - 0.00000000000000000000000000000006594 126.0
SHD1_k127_2794524_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000002121 80.0
SHD1_k127_2806884_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.834e-244 765.0
SHD1_k127_2806884_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
SHD1_k127_2806884_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 370.0
SHD1_k127_2806884_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000003442 250.0
SHD1_k127_2815001_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 6.504e-288 937.0
SHD1_k127_2815001_1 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009155 252.0
SHD1_k127_2815001_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001548 284.0
SHD1_k127_2815001_3 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000003878 140.0
SHD1_k127_2869617_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 449.0
SHD1_k127_2869617_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 299.0
SHD1_k127_2869617_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
SHD1_k127_2869617_3 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
SHD1_k127_2869617_4 - - - - 0.000000000000000000000000000000000000000000000000000001835 201.0
SHD1_k127_2869617_5 Virulence factor BrkB K07058 - - 0.000000000000000000000000002987 122.0
SHD1_k127_2869617_6 AI-2E family transporter - - - 0.0000000000002422 74.0
SHD1_k127_2871384_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 540.0
SHD1_k127_2871384_1 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 437.0
SHD1_k127_2871384_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 370.0
SHD1_k127_2871384_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 327.0
SHD1_k127_2871384_4 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000469 258.0
SHD1_k127_2871384_5 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005021 244.0
SHD1_k127_2871384_6 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000313 135.0
SHD1_k127_2871384_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000001748 75.0
SHD1_k127_2886309_0 Molecular chaperone. Has ATPase activity K04079 - - 2.055e-268 839.0
SHD1_k127_2886309_1 Sugar (and other) transporter K03446 - - 5.617e-234 734.0
SHD1_k127_2886309_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.000000000000000000000000000000000000000003503 159.0
SHD1_k127_2886309_3 SMART Cold shock protein K03704 - - 0.000000000000000000000000007154 110.0
SHD1_k127_2898908_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 608.0
SHD1_k127_2898908_1 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 472.0
SHD1_k127_2898908_2 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 463.0
SHD1_k127_2898908_3 oxidoreductase activity K00316 - 1.5.99.6 0.0000000000000000000000000000000000000000000000002042 183.0
SHD1_k127_2898908_4 Domain of Unknown Function (DUF350) - - - 0.00000000004698 65.0
SHD1_k127_2902423_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 1.553e-198 625.0
SHD1_k127_2902423_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 454.0
SHD1_k127_2902423_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 407.0
SHD1_k127_2902423_3 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 376.0
SHD1_k127_2902423_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 311.0
SHD1_k127_2902423_5 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000005009 222.0
SHD1_k127_2902423_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000002023 182.0
SHD1_k127_29044_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 552.0
SHD1_k127_29044_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 484.0
SHD1_k127_29044_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000001054 154.0
SHD1_k127_29044_11 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000000147 139.0
SHD1_k127_29044_12 succinate dehydrogenase K00241,K00247 - - 0.000000000000000000003634 97.0
SHD1_k127_29044_13 succinate dehydrogenase activity K00242,K00246 - - 0.000000000000000001261 92.0
SHD1_k127_29044_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 437.0
SHD1_k127_29044_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 426.0
SHD1_k127_29044_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 368.0
SHD1_k127_29044_5 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 353.0
SHD1_k127_29044_6 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
SHD1_k127_29044_7 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 288.0
SHD1_k127_29044_8 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
SHD1_k127_29044_9 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000742 269.0
SHD1_k127_2910380_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 5.077e-262 820.0
SHD1_k127_2910380_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 518.0
SHD1_k127_2910380_2 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000001492 145.0
SHD1_k127_2912689_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1155.0
SHD1_k127_2912689_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 568.0
SHD1_k127_2912689_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 435.0
SHD1_k127_2912689_3 PFAM PfkB K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 312.0
SHD1_k127_2912689_4 SMART Tetratricopeptide - - - 0.000000000000000000000012 108.0
SHD1_k127_2917942_0 Glucose-1-phosphate thymidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 433.0
SHD1_k127_2917942_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 418.0
SHD1_k127_2917942_2 Male sterility protein K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006331 278.0
SHD1_k127_2917942_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000005541 190.0
SHD1_k127_2917942_4 - - - - 0.0000000005708 62.0
SHD1_k127_2934643_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 468.0
SHD1_k127_2934643_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 310.0
SHD1_k127_2934643_2 PFAM TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006309 277.0
SHD1_k127_2934643_3 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
SHD1_k127_2934643_4 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000004416 219.0
SHD1_k127_2934643_5 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000001022 215.0
SHD1_k127_2934643_6 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000012 198.0
SHD1_k127_2934643_7 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000003468 192.0
SHD1_k127_2934643_8 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000008237 146.0
SHD1_k127_2934643_9 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000004028 127.0
SHD1_k127_2956860_0 proline betaine transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 537.0
SHD1_k127_2956860_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 481.0
SHD1_k127_2956860_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 427.0
SHD1_k127_2956860_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000004844 235.0
SHD1_k127_2956860_4 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000001147 179.0
SHD1_k127_2956860_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008699 154.0
SHD1_k127_2956860_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000004885 113.0
SHD1_k127_2956860_7 EamA-like transporter family - - - 0.000000000000000000005608 104.0
SHD1_k127_2968745_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 372.0
SHD1_k127_2968745_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 332.0
SHD1_k127_2968745_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000594 227.0
SHD1_k127_2968745_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000003395 153.0
SHD1_k127_2968745_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000002695 134.0
SHD1_k127_2968745_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000001126 87.0
SHD1_k127_2968745_6 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001063 74.0
SHD1_k127_2971955_0 Ftsk_gamma K03466 - - 3.003e-204 658.0
SHD1_k127_2971955_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.008e-201 642.0
SHD1_k127_2971955_10 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000002502 86.0
SHD1_k127_2971955_11 - - - - 0.000000000006715 78.0
SHD1_k127_2971955_12 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.0000000004792 65.0
SHD1_k127_2971955_13 cheY-homologous receiver domain - - - 0.0002844 47.0
SHD1_k127_2971955_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 509.0
SHD1_k127_2971955_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 387.0
SHD1_k127_2971955_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 368.0
SHD1_k127_2971955_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004844 274.0
SHD1_k127_2971955_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000002158 220.0
SHD1_k127_2971955_7 HD domain - - - 0.0000000000000000000000000000000000000000000001091 183.0
SHD1_k127_2971955_8 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000196 145.0
SHD1_k127_2971955_9 domain, Protein K00703,K07082 - 2.4.1.21 0.0000000000000002133 84.0
SHD1_k127_2982853_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.671e-246 764.0
SHD1_k127_2982853_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 497.0
SHD1_k127_2982853_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000001083 134.0
SHD1_k127_2982853_11 Protein required for attachment to host cells - - - 0.000000000000000000000000001412 117.0
SHD1_k127_2982853_12 Autoinducer binding domain K20334 - - 0.000000000000000615 80.0
SHD1_k127_2982853_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 469.0
SHD1_k127_2982853_3 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 480.0
SHD1_k127_2982853_4 response regulator receiver K02481,K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 396.0
SHD1_k127_2982853_5 radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 383.0
SHD1_k127_2982853_6 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 385.0
SHD1_k127_2982853_7 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000002757 213.0
SHD1_k127_2982853_8 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000438 204.0
SHD1_k127_2982853_9 PFAM Amidohydrolase 2 - - - 0.0000000000000000000000000000000000005493 153.0
SHD1_k127_3012938_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.023e-198 631.0
SHD1_k127_3012938_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 484.0
SHD1_k127_3012938_2 Mo-molybdopterin cofactor metabolic process K02379 - - 0.0000000000000000000000000000000000000003928 155.0
SHD1_k127_3012938_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.000000000000000000151 88.0
SHD1_k127_3012938_4 - - - - 0.0002677 44.0
SHD1_k127_3032309_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 587.0
SHD1_k127_3032309_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 521.0
SHD1_k127_3032309_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 414.0
SHD1_k127_3032309_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 291.0
SHD1_k127_3032309_4 Pectate lyase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001474 262.0
SHD1_k127_3032309_5 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000007193 248.0
SHD1_k127_3032309_6 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000001447 200.0
SHD1_k127_3032309_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000006035 62.0
SHD1_k127_3048201_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 1.458e-292 914.0
SHD1_k127_3048201_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 313.0
SHD1_k127_3048201_10 Molybdopterin biosynthesis-like protein MoeZ K21147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.80,2.8.1.11 0.0009174 44.0
SHD1_k127_3048201_2 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003263 272.0
SHD1_k127_3048201_3 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001067 253.0
SHD1_k127_3048201_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000004537 236.0
SHD1_k127_3048201_5 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000007614 195.0
SHD1_k127_3048201_6 PFAM CBS domain - - - 0.000000000000000000000000000000000004654 141.0
SHD1_k127_3048201_7 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000002948 110.0
SHD1_k127_3048201_8 PFAM Methylamine - - - 0.0000000000000001263 86.0
SHD1_k127_3048201_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000002008 61.0
SHD1_k127_3051265_0 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 383.0
SHD1_k127_3051265_1 - - - - 0.0000000000000000000000000000000000000000000721 183.0
SHD1_k127_3051265_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000001358 78.0
SHD1_k127_3051265_3 ABC transporter substrate binding protein K01989 - - 0.00000000000001729 84.0
SHD1_k127_3058400_0 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 6.26e-220 704.0
SHD1_k127_3058400_1 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 408.0
SHD1_k127_3058400_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000006622 222.0
SHD1_k127_3058400_3 Formyl transferase - - - 0.000000000000000000000000000000001707 140.0
SHD1_k127_3058400_4 Tetratricopeptide repeat - - - 0.000000000000347 79.0
SHD1_k127_3058400_5 Polysaccharide deacetylase - - - 0.0000000000008202 79.0
SHD1_k127_3098974_0 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 425.0
SHD1_k127_3098974_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000002367 181.0
SHD1_k127_3098974_2 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000001187 150.0
SHD1_k127_3098974_4 lyase activity - - - 0.0003888 47.0
SHD1_k127_3104016_0 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000003933 192.0
SHD1_k127_3104016_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000002577 150.0
SHD1_k127_3104016_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000008691 114.0
SHD1_k127_3104016_3 PFAM thiamineS protein - - - 0.00000000000007439 73.0
SHD1_k127_3133570_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 406.0
SHD1_k127_3133570_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 318.0
SHD1_k127_3133570_2 - - - - 0.00000000000000000000000000000000000000000000000000000001566 203.0
SHD1_k127_3133570_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000007846 183.0
SHD1_k127_3133570_4 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000002862 128.0
SHD1_k127_3133570_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000004043 94.0
SHD1_k127_3134822_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 493.0
SHD1_k127_3134822_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 400.0
SHD1_k127_3134822_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
SHD1_k127_3134822_3 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000002368 185.0
SHD1_k127_3134822_4 Methyltransferase domain - - - 0.000000000000000000000000000001362 129.0
SHD1_k127_3145853_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1156.0
SHD1_k127_3145853_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 5.238e-213 666.0
SHD1_k127_3145853_2 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 526.0
SHD1_k127_3145853_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 524.0
SHD1_k127_3145853_4 K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 381.0
SHD1_k127_3145853_5 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 321.0
SHD1_k127_3145853_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000002313 244.0
SHD1_k127_3145853_7 ThiS family K03636 - - 0.0000000000000000000000000000000006004 132.0
SHD1_k127_3145853_8 NIL - - - 0.000000000000000000000000009561 113.0
SHD1_k127_3145853_9 LemA family K03744 - - 0.0000002624 57.0
SHD1_k127_3155779_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 492.0
SHD1_k127_3155779_1 ABC transporter K02021,K06147,K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 501.0
SHD1_k127_3155779_10 AMP binding - - - 0.000000000000000000000000000000000000000551 160.0
SHD1_k127_3155779_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000002582 125.0
SHD1_k127_3155779_12 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000002892 103.0
SHD1_k127_3155779_13 O-Antigen ligase K02847 - - 0.0000000000001404 83.0
SHD1_k127_3155779_14 CYTH K05873 - 4.6.1.1 0.000000000002791 74.0
SHD1_k127_3155779_15 - - - - 0.000000000002918 70.0
SHD1_k127_3155779_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 329.0
SHD1_k127_3155779_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 300.0
SHD1_k127_3155779_4 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 296.0
SHD1_k127_3155779_5 protein tyrosine phosphatase activity K01104,K19302 - 3.1.3.48,3.6.1.27 0.00000000000000000000000000000000000000000000000000001561 192.0
SHD1_k127_3155779_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000005947 197.0
SHD1_k127_3155779_7 glycogen (starch) synthase activity - - - 0.000000000000000000000000000000000000000000000000004375 196.0
SHD1_k127_3155779_8 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000006156 174.0
SHD1_k127_3155779_9 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000001539 160.0
SHD1_k127_3177080_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 462.0
SHD1_k127_3177080_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 419.0
SHD1_k127_3177080_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 337.0
SHD1_k127_3177080_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
SHD1_k127_3177080_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000008483 166.0
SHD1_k127_3177080_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000261 74.0
SHD1_k127_3177080_6 PFAM DSBA oxidoreductase - - - 0.0007259 45.0
SHD1_k127_3209469_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 350.0
SHD1_k127_3209469_2 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.000000006912 59.0
SHD1_k127_3211520_0 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0 1137.0
SHD1_k127_3211520_1 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 310.0
SHD1_k127_3211520_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 292.0
SHD1_k127_3211520_3 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 276.0
SHD1_k127_3211520_4 GAF domain - - - 0.0000000000001356 82.0
SHD1_k127_3292793_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 548.0
SHD1_k127_3292793_1 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000006759 159.0
SHD1_k127_3297150_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1079.0
SHD1_k127_3297150_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.629e-194 613.0
SHD1_k127_3297150_10 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000001185 111.0
SHD1_k127_3297150_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 571.0
SHD1_k127_3297150_3 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 419.0
SHD1_k127_3297150_4 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 416.0
SHD1_k127_3297150_5 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 372.0
SHD1_k127_3297150_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 329.0
SHD1_k127_3297150_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006738 269.0
SHD1_k127_3297150_8 histidine kinase, HAMP K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000003603 246.0
SHD1_k127_3297150_9 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000002916 169.0
SHD1_k127_330343_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 526.0
SHD1_k127_330343_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 465.0
SHD1_k127_330343_2 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 327.0
SHD1_k127_330343_3 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003449 246.0
SHD1_k127_330343_4 NTPase - - - 0.0000000000000000000000000000000000000001574 156.0
SHD1_k127_330343_5 Uncharacterised protein family (UPF0158) - - - 0.000000009394 63.0
SHD1_k127_331831_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 461.0
SHD1_k127_331831_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 327.0
SHD1_k127_331831_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 286.0
SHD1_k127_3323241_0 Elongation factor SelB, winged helix K03833 - - 1.591e-210 671.0
SHD1_k127_3323241_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 447.0
SHD1_k127_3323241_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 287.0
SHD1_k127_3323241_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000001471 178.0
SHD1_k127_3323241_4 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000007108 161.0
SHD1_k127_3323241_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000445 93.0
SHD1_k127_3323241_7 peptidyl-tyrosine sulfation - - - 0.000000002508 70.0
SHD1_k127_3323241_8 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000001493 54.0
SHD1_k127_3325361_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1394.0
SHD1_k127_3325361_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 474.0
SHD1_k127_3325361_10 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000005787 59.0
SHD1_k127_3325361_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 399.0
SHD1_k127_3325361_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 317.0
SHD1_k127_3325361_4 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005895 275.0
SHD1_k127_3325361_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001696 241.0
SHD1_k127_3325361_6 Cytochrome P460 - - - 0.00000000000000000000000000000000000001708 150.0
SHD1_k127_3325361_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000277 127.0
SHD1_k127_3325361_8 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000001012 113.0
SHD1_k127_3325361_9 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.0000000000000000000897 105.0
SHD1_k127_3343124_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 527.0
SHD1_k127_3343124_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
SHD1_k127_3343124_10 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.0000000000000000000000000000000000000001045 160.0
SHD1_k127_3343124_11 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0000000000000000000000000000000000009601 139.0
SHD1_k127_3343124_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000008341 126.0
SHD1_k127_3343124_13 cheY-homologous receiver domain - - - 0.000000000000000000000794 99.0
SHD1_k127_3343124_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000001348 98.0
SHD1_k127_3343124_15 YbbR-like protein - - - 0.00003924 55.0
SHD1_k127_3343124_2 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 359.0
SHD1_k127_3343124_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 351.0
SHD1_k127_3343124_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 323.0
SHD1_k127_3343124_5 PFAM ATP-binding region, ATPase-like histidine kinase A-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 316.0
SHD1_k127_3343124_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007351 254.0
SHD1_k127_3343124_7 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000005409 231.0
SHD1_k127_3343124_8 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000002154 199.0
SHD1_k127_3343124_9 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000001437 204.0
SHD1_k127_3349008_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1009.0
SHD1_k127_3349008_1 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 477.0
SHD1_k127_3349008_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 327.0
SHD1_k127_3349008_3 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000007474 241.0
SHD1_k127_3349008_4 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000003645 228.0
SHD1_k127_3349008_5 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000001623 192.0
SHD1_k127_3349008_6 ABC 3 transport family K09816,K09819 - - 0.00000000000000000000000000000000000000000004293 166.0
SHD1_k127_3349008_7 response regulator - - - 0.0000000000000000000000000000000008364 143.0
SHD1_k127_3349008_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000001615 129.0
SHD1_k127_3349008_9 Regulatory protein, FmdB family - - - 0.000000003321 59.0
SHD1_k127_3355358_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 3.044e-196 620.0
SHD1_k127_3355358_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 527.0
SHD1_k127_3355358_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 483.0
SHD1_k127_3355358_3 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 447.0
SHD1_k127_3355358_4 oxidoreductase activity K00316 - 1.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
SHD1_k127_3355358_5 Spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000063 276.0
SHD1_k127_3355358_6 - - - - 0.0000000000002277 73.0
SHD1_k127_3355358_7 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000008711 66.0
SHD1_k127_3366831_0 O-methyltransferase activity - - - 7.275e-208 665.0
SHD1_k127_3366831_1 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 582.0
SHD1_k127_3366831_10 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000891 115.0
SHD1_k127_3366831_11 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000000001536 116.0
SHD1_k127_3366831_12 Major Facilitator Superfamily - - - 0.0004424 45.0
SHD1_k127_3366831_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 438.0
SHD1_k127_3366831_3 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000134 261.0
SHD1_k127_3366831_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001339 254.0
SHD1_k127_3366831_5 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000002523 222.0
SHD1_k127_3366831_6 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000001027 202.0
SHD1_k127_3366831_7 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000002182 206.0
SHD1_k127_3366831_8 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000002291 209.0
SHD1_k127_3366831_9 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000000000000000000000000000000000007299 172.0
SHD1_k127_3369287_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 396.0
SHD1_k127_3369287_1 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002982 273.0
SHD1_k127_3369287_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000002275 95.0
SHD1_k127_3369287_4 PFAM Smr protein MutS2 - - - 0.00006318 45.0
SHD1_k127_3385995_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 381.0
SHD1_k127_3385995_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000002523 201.0
SHD1_k127_3385995_2 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000014 109.0
SHD1_k127_3385995_3 Outer membrane efflux protein - - - 0.000000000007241 78.0
SHD1_k127_3385995_4 MacB-like periplasmic core domain K02004 - - 0.0004035 45.0
SHD1_k127_3395841_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 442.0
SHD1_k127_3395841_1 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
SHD1_k127_3395841_2 ATPase (AAA superfamily) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 243.0
SHD1_k127_3395841_3 PFAM aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000591 171.0
SHD1_k127_340540_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 4.04e-206 649.0
SHD1_k127_340540_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 468.0
SHD1_k127_340540_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 294.0
SHD1_k127_340540_3 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000001747 165.0
SHD1_k127_340540_4 diguanylate cyclase - - - 0.00000000000000000000000000000000002644 153.0
SHD1_k127_340540_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000001409 98.0
SHD1_k127_3440507_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 5.683e-227 707.0
SHD1_k127_3440507_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 603.0
SHD1_k127_3440507_2 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 494.0
SHD1_k127_3440507_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 335.0
SHD1_k127_3440507_4 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000009705 219.0
SHD1_k127_3440507_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000003776 198.0
SHD1_k127_3440507_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000005143 184.0
SHD1_k127_3440507_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000002113 124.0
SHD1_k127_3440507_8 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000006051 79.0
SHD1_k127_3448063_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 2.117e-225 716.0
SHD1_k127_3448063_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 418.0
SHD1_k127_3448063_10 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007912 278.0
SHD1_k127_3448063_11 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004474 209.0
SHD1_k127_3448063_12 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000000009684 175.0
SHD1_k127_3448063_13 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000006709 154.0
SHD1_k127_3448063_14 Nitrate reductase gamma subunit - - - 0.0000000000000000001079 97.0
SHD1_k127_3448063_15 OsmC-like protein - - - 0.00000000000000001009 87.0
SHD1_k127_3448063_16 - - - - 0.000000000000008867 78.0
SHD1_k127_3448063_17 PFAM Nitrate reductase gamma subunit - - - 0.0000000006558 69.0
SHD1_k127_3448063_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
SHD1_k127_3448063_3 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 339.0
SHD1_k127_3448063_4 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 319.0
SHD1_k127_3448063_5 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 328.0
SHD1_k127_3448063_6 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 323.0
SHD1_k127_3448063_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 314.0
SHD1_k127_3448063_8 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 316.0
SHD1_k127_3448063_9 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003891 271.0
SHD1_k127_3455348_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.943e-289 911.0
SHD1_k127_3455348_1 UvrD-like helicase C-terminal domain K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 607.0
SHD1_k127_3455348_10 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000004519 106.0
SHD1_k127_3455348_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000732 81.0
SHD1_k127_3455348_12 - - - - 0.00000000008027 65.0
SHD1_k127_3455348_13 peptidyl-histidine dephosphorylation K01112 GO:0000003,GO:0002682,GO:0002683,GO:0002791,GO:0002793,GO:0003006,GO:0003674,GO:0003824,GO:0004721,GO:0005246,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007548,GO:0008150,GO:0008152,GO:0008200,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010647,GO:0010648,GO:0010817,GO:0016247,GO:0016248,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0019855,GO:0022414,GO:0023051,GO:0023056,GO:0023057,GO:0032024,GO:0032502,GO:0032879,GO:0032880,GO:0032956,GO:0032970,GO:0033043,GO:0035774,GO:0035971,GO:0036211,GO:0040012,GO:0040017,GO:0042578,GO:0043086,GO:0043170,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044325,GO:0044424,GO:0044444,GO:0044464,GO:0046883,GO:0046887,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050708,GO:0050714,GO:0050776,GO:0050789,GO:0050790,GO:0050794,GO:0050796,GO:0050854,GO:0050856,GO:0050858,GO:0050860,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051128,GO:0051222,GO:0051223,GO:0051270,GO:0051272,GO:0051338,GO:0051339,GO:0051348,GO:0051350,GO:0051493,GO:0060341,GO:0061178,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0071704,GO:0090087,GO:0090276,GO:0090277,GO:0098772,GO:0099106,GO:0101006,GO:0140096,GO:1901564,GO:1903530,GO:1903532,GO:1904951,GO:2000145,GO:2000147,GO:2000249,GO:2000983,GO:2000984 3.9.1.3 0.00004144 52.0
SHD1_k127_3455348_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 524.0
SHD1_k127_3455348_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 329.0
SHD1_k127_3455348_4 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000000005008 183.0
SHD1_k127_3455348_5 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000479 158.0
SHD1_k127_3455348_6 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000002754 133.0
SHD1_k127_3455348_7 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000009858 114.0
SHD1_k127_3455348_8 Domain of unknown function (DUF4203) - - - 0.00000000000000000000000001316 115.0
SHD1_k127_3455348_9 - - - - 0.0000000000000000000000003039 109.0
SHD1_k127_3458337_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 6.817e-217 679.0
SHD1_k127_3458337_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
SHD1_k127_3458337_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 409.0
SHD1_k127_3458337_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 334.0
SHD1_k127_3458337_4 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007146 261.0
SHD1_k127_3458337_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000004536 212.0
SHD1_k127_3465808_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 576.0
SHD1_k127_3465808_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 346.0
SHD1_k127_3465808_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 241.0
SHD1_k127_3465808_3 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000001182 220.0
SHD1_k127_3465808_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000004902 207.0
SHD1_k127_3465808_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000008149 192.0
SHD1_k127_3465808_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000005739 123.0
SHD1_k127_3465808_7 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000002557 76.0
SHD1_k127_3477634_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 542.0
SHD1_k127_3477634_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 513.0
SHD1_k127_3477634_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 431.0
SHD1_k127_3477634_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
SHD1_k127_3477634_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004846 235.0
SHD1_k127_3477634_5 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000002063 216.0
SHD1_k127_3477634_6 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000002161 196.0
SHD1_k127_3477634_7 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000001443 163.0
SHD1_k127_3477634_8 - - - - 0.000004013 57.0
SHD1_k127_3480414_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000002869 212.0
SHD1_k127_3480414_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000004676 190.0
SHD1_k127_3480414_2 Glycosyl transferases group 1 - - - 0.00002499 52.0
SHD1_k127_3488148_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 387.0
SHD1_k127_3488148_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
SHD1_k127_3488148_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001977 147.0
SHD1_k127_3496101_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 0.0 1075.0
SHD1_k127_3496101_1 Protein of unknown function, DUF255 K06888 - - 1.021e-253 798.0
SHD1_k127_3496101_10 NAD dependent epimerase dehydratase family protein - - - 0.00000000000000000000000000000002631 138.0
SHD1_k127_3496101_12 Predicted membrane protein (DUF2318) - - - 0.0000000000000000002048 93.0
SHD1_k127_3496101_13 Homologous to orf229 gp Streptococcus thermophilus bacteriophage Sfi19 gi 9632919 ref NP_049948.1 - - - 0.000000000000000008735 89.0
SHD1_k127_3496101_15 peroxiredoxin activity - - - 0.00000377 49.0
SHD1_k127_3496101_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 433.0
SHD1_k127_3496101_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 361.0
SHD1_k127_3496101_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
SHD1_k127_3496101_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003758 284.0
SHD1_k127_3496101_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000003025 238.0
SHD1_k127_3496101_7 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000005152 222.0
SHD1_k127_3496101_8 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000001732 221.0
SHD1_k127_3496101_9 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000006101 196.0
SHD1_k127_3503097_0 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000000001035 190.0
SHD1_k127_3503097_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000001928 177.0
SHD1_k127_3503097_2 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000008776 132.0
SHD1_k127_3503097_3 regulatory protein ArsR K03892 - - 0.000000000000000000000364 101.0
SHD1_k127_3503097_4 Histidine kinase - - - 0.0000001252 58.0
SHD1_k127_3503097_6 Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor - - - 0.0004167 46.0
SHD1_k127_3504873_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 387.0
SHD1_k127_3504873_1 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000001205 153.0
SHD1_k127_3504873_2 - - - - 0.000000000000000000000000001256 123.0
SHD1_k127_3504873_3 Protein of unknown function DUF134 - - - 0.000000000000000000000000011 111.0
SHD1_k127_3504873_4 Antioxidant, AhpC TSA family - - - 0.0000000000005983 72.0
SHD1_k127_3504873_5 Thioredoxin-like - - - 0.0000402 49.0
SHD1_k127_3518582_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 475.0
SHD1_k127_3518582_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 388.0
SHD1_k127_3518582_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
SHD1_k127_3518582_3 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000000077 120.0
SHD1_k127_3542876_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 5.518e-206 676.0
SHD1_k127_3542876_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 580.0
SHD1_k127_3542876_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 445.0
SHD1_k127_3542876_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000177 206.0
SHD1_k127_3542876_4 Adenylate kinase - - - 0.0000000000000000000000000000000000000000000000003281 183.0
SHD1_k127_3542876_5 GAF domain - - - 0.000000000000000000000000000000000000000000001268 180.0
SHD1_k127_3542876_6 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000192 75.0
SHD1_k127_3550905_0 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005571 304.0
SHD1_k127_3550905_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000001317 229.0
SHD1_k127_3550905_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000001016 218.0
SHD1_k127_3550905_3 group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000005149 215.0
SHD1_k127_3550905_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000002271 209.0
SHD1_k127_3550905_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000001032 191.0
SHD1_k127_3550905_6 - - - - 0.000000000000007556 84.0
SHD1_k127_3550905_7 Uncharacterized conserved protein (DUF2304) - - - 0.00000000008566 67.0
SHD1_k127_3550905_8 - - - - 0.0000001297 59.0
SHD1_k127_3570120_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 509.0
SHD1_k127_3570120_1 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 359.0
SHD1_k127_3570120_2 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 310.0
SHD1_k127_3571750_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 540.0
SHD1_k127_3571750_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 369.0
SHD1_k127_3571750_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 319.0
SHD1_k127_3571750_3 Branched-chain amino acid ABC transporter, ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005931 275.0
SHD1_k127_3571750_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
SHD1_k127_3583937_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 559.0
SHD1_k127_3583937_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000001642 215.0
SHD1_k127_3583937_2 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000001185 93.0
SHD1_k127_3583937_3 Glycosyl hydrolases family 43 - - - 0.0000000000000000005438 91.0
SHD1_k127_3583937_4 - - - - 0.0000001389 53.0
SHD1_k127_3583937_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000001389 53.0
SHD1_k127_3583937_6 Evidence 5 No homology to any previously reported sequences - - - 0.00000152 50.0
SHD1_k127_3598661_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 578.0
SHD1_k127_3598661_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 578.0
SHD1_k127_3598661_2 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 560.0
SHD1_k127_3598661_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 315.0
SHD1_k127_3598661_4 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000002835 183.0
SHD1_k127_3598661_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000001483 87.0
SHD1_k127_3608164_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1355.0
SHD1_k127_3608164_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 608.0
SHD1_k127_3608164_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
SHD1_k127_3608164_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000164 251.0
SHD1_k127_3608164_4 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001009 219.0
SHD1_k127_3608164_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000003555 193.0
SHD1_k127_3630415_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 475.0
SHD1_k127_3630415_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 348.0
SHD1_k127_3649346_0 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000003945 147.0
SHD1_k127_3649346_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000107 97.0
SHD1_k127_3649346_2 Ferredoxin K05337 - - 0.0000000000000002777 80.0
SHD1_k127_3649346_3 PFAM Sulfotransferase domain - - - 0.0000000002115 70.0
SHD1_k127_3649346_4 SEC-C Motif Domain Protein - - - 0.000000001356 67.0
SHD1_k127_3663145_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
SHD1_k127_3663145_1 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001188 277.0
SHD1_k127_3663145_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001434 269.0
SHD1_k127_3663145_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004366 261.0
SHD1_k127_3663145_4 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001145 247.0
SHD1_k127_3663145_5 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000006058 176.0
SHD1_k127_3663145_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000001017 117.0
SHD1_k127_3663145_7 antisigma factor binding K04749,K05946,K06378 - 2.4.1.187 0.00000000000000009318 83.0
SHD1_k127_3663145_8 PFAM Mammalian cell entry related K02067 - - 0.000000000000001058 87.0
SHD1_k127_3663145_9 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00004516 53.0
SHD1_k127_3678857_0 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004602 270.0
SHD1_k127_3678857_1 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000017 230.0
SHD1_k127_3678857_2 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000002312 134.0
SHD1_k127_3678857_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000005141 114.0
SHD1_k127_3709356_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 409.0
SHD1_k127_3709356_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 351.0
SHD1_k127_3709356_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007877 250.0
SHD1_k127_3775576_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 382.0
SHD1_k127_3775576_1 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 330.0
SHD1_k127_3775576_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002403 234.0
SHD1_k127_3775576_3 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000006347 68.0
SHD1_k127_3775576_4 - - - - 0.000000009119 59.0
SHD1_k127_3800866_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.444e-276 862.0
SHD1_k127_3800866_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000001028 190.0
SHD1_k127_3800866_2 PFAM UspA - - - 0.00000000000000000000000000000000000000000000000001384 190.0
SHD1_k127_3800866_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000001586 130.0
SHD1_k127_3800866_4 - - - - 0.000000000000002736 75.0
SHD1_k127_3803263_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.621e-282 875.0
SHD1_k127_3803263_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 355.0
SHD1_k127_3803263_2 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000003027 170.0
SHD1_k127_3803263_3 Methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000002784 141.0
SHD1_k127_3853081_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 325.0
SHD1_k127_3853081_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000001633 239.0
SHD1_k127_3853081_2 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000001119 175.0
SHD1_k127_3853081_3 Glycosyltransferase like family 2 K12992 - - 0.0000000000000000000000000000000000001523 152.0
SHD1_k127_3853081_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000005783 126.0
SHD1_k127_3853081_5 PFAM Response regulator receiver domain K07658 - - 0.0000000005128 71.0
SHD1_k127_3853081_6 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.0007427 42.0
SHD1_k127_3855559_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.983e-216 682.0
SHD1_k127_3855559_1 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 578.0
SHD1_k127_3855559_2 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 438.0
SHD1_k127_3855559_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 300.0
SHD1_k127_3855559_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
SHD1_k127_3855559_5 - - - - 0.0000000000000000000000000003151 115.0
SHD1_k127_3855559_6 protein-glutamate methylesterase activity K00575,K03412,K03413,K07719 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0000000000000000421 89.0
SHD1_k127_3855559_7 - - - - 0.0000000000000001945 82.0
SHD1_k127_3855559_8 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00001121 56.0
SHD1_k127_3870471_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 373.0
SHD1_k127_3870471_1 Hydrogenase (NiFe) small subunit HydA K05927,K06282,K18008 - 1.12.2.1,1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 299.0
SHD1_k127_3870471_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
SHD1_k127_3870471_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000002613 203.0
SHD1_k127_3870471_4 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000812 162.0
SHD1_k127_3870471_5 PFAM cytochrome c class I - - - 0.0000000006496 64.0
SHD1_k127_3870471_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000007591 57.0
SHD1_k127_3890690_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.616e-198 625.0
SHD1_k127_3890690_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 491.0
SHD1_k127_3890690_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000004765 258.0
SHD1_k127_3890690_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008947 239.0
SHD1_k127_3923071_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 1.856e-249 789.0
SHD1_k127_3923071_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 344.0
SHD1_k127_39257_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1067.0
SHD1_k127_39257_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.131e-251 784.0
SHD1_k127_39257_10 ATPases associated with a variety of cellular activities K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
SHD1_k127_39257_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000195 273.0
SHD1_k127_39257_12 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001264 235.0
SHD1_k127_39257_13 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
SHD1_k127_39257_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000002125 204.0
SHD1_k127_39257_15 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000007211 184.0
SHD1_k127_39257_16 OstA-like protein K09774 - - 0.000000000000000000000000000000000003255 142.0
SHD1_k127_39257_17 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000019 127.0
SHD1_k127_39257_18 Protein of unknown function (DUF3187) - - - 0.0000000000000000000000001721 118.0
SHD1_k127_39257_19 PASTA K12132 - 2.7.11.1 0.00000000009781 71.0
SHD1_k127_39257_2 Sigma54 specific transcriptional regulator, Fis family - - - 4.706e-210 668.0
SHD1_k127_39257_20 competence protein - - - 0.00000009468 64.0
SHD1_k127_39257_22 type IV pilus secretin PilQ K02666 - - 0.0002242 50.0
SHD1_k127_39257_23 Lipopolysaccharide-assembly, LptC-related - - - 0.0004188 49.0
SHD1_k127_39257_3 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 572.0
SHD1_k127_39257_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 481.0
SHD1_k127_39257_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 452.0
SHD1_k127_39257_6 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 448.0
SHD1_k127_39257_7 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 431.0
SHD1_k127_39257_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 340.0
SHD1_k127_39257_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 286.0
SHD1_k127_3963796_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 580.0
SHD1_k127_3963796_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 497.0
SHD1_k127_3963796_2 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 252.0
SHD1_k127_3963796_3 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000002494 183.0
SHD1_k127_3963796_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000002771 173.0
SHD1_k127_3963796_5 - K07112 - - 0.0000000000000000000000000000000000001988 146.0
SHD1_k127_3963796_6 TM2 domain - - - 0.0000000000000000000000000000000004388 135.0
SHD1_k127_3963796_7 Glutathione peroxidase - - - 0.0000000000000000000000000000000004468 137.0
SHD1_k127_3969346_0 glycosyl transferase group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 401.0
SHD1_k127_3969346_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 308.0
SHD1_k127_3969346_2 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 293.0
SHD1_k127_3969346_3 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006359 246.0
SHD1_k127_3969346_4 - - - - 0.00000000000000003922 96.0
SHD1_k127_3969346_5 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000009037 82.0
SHD1_k127_3993451_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1080.0
SHD1_k127_3993451_1 GAF domain - - - 4.98e-203 683.0
SHD1_k127_3993451_10 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000009481 137.0
SHD1_k127_3993451_11 radical SAM domain protein - - - 0.0000000000000000000000000000001565 136.0
SHD1_k127_3993451_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 427.0
SHD1_k127_3993451_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 419.0
SHD1_k127_3993451_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 393.0
SHD1_k127_3993451_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 313.0
SHD1_k127_3993451_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
SHD1_k127_3993451_7 2Fe-2S -binding domain K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
SHD1_k127_3993451_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000219 247.0
SHD1_k127_3993451_9 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000001516 170.0
SHD1_k127_3996742_0 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 398.0
SHD1_k127_3996742_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 327.0
SHD1_k127_3996742_2 Domain of unknown function (DUF4115) - - - 0.00000000000000005354 89.0
SHD1_k127_4041480_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.141e-283 881.0
SHD1_k127_4041480_1 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 484.0
SHD1_k127_4041480_2 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 432.0
SHD1_k127_4041480_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
SHD1_k127_4041480_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000981 183.0
SHD1_k127_4041480_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000003549 151.0
SHD1_k127_4041480_6 Amidohydrolase - - - 0.0000000000000000000000000000000005927 145.0
SHD1_k127_4041480_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000004032 87.0
SHD1_k127_4041480_8 CGGC - - - 0.00000000000007347 71.0
SHD1_k127_4041480_9 FMN reductase (NADPH) activity - - - 0.000000000001785 70.0
SHD1_k127_4051805_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 6.158e-208 655.0
SHD1_k127_4051805_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
SHD1_k127_4051805_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001628 245.0
SHD1_k127_4051805_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000001469 174.0
SHD1_k127_4051805_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000001597 174.0
SHD1_k127_4051805_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000001282 110.0
SHD1_k127_4067423_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 497.0
SHD1_k127_4067423_1 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 405.0
SHD1_k127_4067423_10 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000002998 49.0
SHD1_k127_4067423_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 336.0
SHD1_k127_4067423_3 Mur ligase family, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 312.0
SHD1_k127_4067423_4 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000008982 213.0
SHD1_k127_4067423_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001016 208.0
SHD1_k127_4067423_6 nucleotide metabolic process - - - 0.00000000000000000000000000000000000003774 152.0
SHD1_k127_4067423_7 - - - - 0.00000000000000000000000000000005802 128.0
SHD1_k127_4067423_8 Transcriptional regulator - - - 0.00000000000000000000002532 103.0
SHD1_k127_4067423_9 Transposase - - - 0.00000000000000008147 81.0
SHD1_k127_4087322_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 444.0
SHD1_k127_4087322_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 429.0
SHD1_k127_4087322_10 Membrane - - - 0.00000000000000000000001066 109.0
SHD1_k127_4087322_12 - - - - 0.00000000000000003435 89.0
SHD1_k127_4087322_13 Membrane - - - 0.0000000000000002883 87.0
SHD1_k127_4087322_14 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000531 63.0
SHD1_k127_4087322_15 ABC transporter K06158 - - 0.00000002141 57.0
SHD1_k127_4087322_16 Plasmid stabilization system - - - 0.000000261 53.0
SHD1_k127_4087322_17 - - - - 0.000001888 50.0
SHD1_k127_4087322_18 Transposase IS200 like - - - 0.0002999 44.0
SHD1_k127_4087322_2 PFAM MscS Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 383.0
SHD1_k127_4087322_3 GNAT family acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001066 220.0
SHD1_k127_4087322_4 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000001502 207.0
SHD1_k127_4087322_6 - - - - 0.000000000000000000000000000000000000000000000004868 178.0
SHD1_k127_4087322_7 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000004081 160.0
SHD1_k127_4087322_8 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000004425 161.0
SHD1_k127_4087322_9 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000001494 112.0
SHD1_k127_409793_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005554 278.0
SHD1_k127_409793_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
SHD1_k127_409793_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003344 204.0
SHD1_k127_409793_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005801 201.0
SHD1_k127_409793_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000005833 145.0
SHD1_k127_409793_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000001207 133.0
SHD1_k127_409793_6 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001906 105.0
SHD1_k127_409793_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000003437 88.0
SHD1_k127_409793_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000002008 61.0
SHD1_k127_4103822_0 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 7.817e-253 797.0
SHD1_k127_4103822_1 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 616.0
SHD1_k127_4103822_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 593.0
SHD1_k127_4103822_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 465.0
SHD1_k127_4103822_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 458.0
SHD1_k127_4103822_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 436.0
SHD1_k127_4103822_6 belongs to the CobB CobQ family K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 318.0
SHD1_k127_4103822_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 286.0
SHD1_k127_4103822_8 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 226.0
SHD1_k127_4111715_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 336.0
SHD1_k127_4111715_1 rRNA (uridine-N3-)-methyltransferase activity K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
SHD1_k127_4111715_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001456 281.0
SHD1_k127_4111715_3 PFAM PHP domain - - - 0.000000000000000000000000000000000000000000001693 171.0
SHD1_k127_4111715_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000003712 117.0
SHD1_k127_4111715_5 - - - - 0.000000000001284 71.0
SHD1_k127_4138776_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.942e-234 734.0
SHD1_k127_4138776_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 345.0
SHD1_k127_4138776_2 PFAM NADH Ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000003716 226.0
SHD1_k127_4138776_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000004234 218.0
SHD1_k127_4138776_4 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000008016 148.0
SHD1_k127_4138776_5 Type II secretion system protein B K02451 - - 0.000000000000001118 85.0
SHD1_k127_4149446_0 DEAD DEAH box helicase K06877 - - 3.463e-211 681.0
SHD1_k127_4149446_1 Chain length determinant protein K16554 - - 7.75e-209 672.0
SHD1_k127_4149446_10 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 228.0
SHD1_k127_4149446_11 - - - - 0.0000000000000000000000000000000000000000000000000000000005206 207.0
SHD1_k127_4149446_12 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000000000001791 188.0
SHD1_k127_4149446_13 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000002536 179.0
SHD1_k127_4149446_14 phosphatase activity K05967 - - 0.000000000000000000000000000000000000000006324 160.0
SHD1_k127_4149446_15 protein-disulfide reductase activity - - - 0.000000000000000000000000002958 116.0
SHD1_k127_4149446_17 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000003143 111.0
SHD1_k127_4149446_18 FHA domain - - - 0.00000000001032 76.0
SHD1_k127_4149446_19 - - - - 0.000000005053 57.0
SHD1_k127_4149446_2 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 559.0
SHD1_k127_4149446_20 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.00000003294 65.0
SHD1_k127_4149446_21 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000007675 54.0
SHD1_k127_4149446_22 Protein of unknown function (DUF2934) - - - 0.00005518 49.0
SHD1_k127_4149446_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 412.0
SHD1_k127_4149446_4 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 392.0
SHD1_k127_4149446_5 Glycosyl transferase, family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 322.0
SHD1_k127_4149446_6 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 302.0
SHD1_k127_4149446_7 export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 283.0
SHD1_k127_4149446_8 Putative beta-barrel porin 2 K20920 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 285.0
SHD1_k127_4149446_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000005662 243.0
SHD1_k127_4153183_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 349.0
SHD1_k127_4153183_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000003767 173.0
SHD1_k127_4153183_2 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.0000000000000000001192 101.0
SHD1_k127_4153183_3 Roadblock/LC7 domain - - - 0.0000000000000000002808 92.0
SHD1_k127_4153183_4 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000001322 63.0
SHD1_k127_4161053_0 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000002799 193.0
SHD1_k127_4161053_1 - - - - 0.00000000000000000000000000000000000000000000002695 175.0
SHD1_k127_4161053_2 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000000000002417 168.0
SHD1_k127_4161053_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000003137 150.0
SHD1_k127_4161053_4 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000004711 117.0
SHD1_k127_4161053_6 - - - - 0.0000000000001 74.0
SHD1_k127_4161053_7 Protein of unknown function DUF116 - - - 0.00000001388 64.0
SHD1_k127_4170876_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 348.0
SHD1_k127_4170876_1 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000006013 255.0
SHD1_k127_4170876_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000004271 186.0
SHD1_k127_4170876_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000001602 139.0
SHD1_k127_4170876_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000003534 126.0
SHD1_k127_4170876_5 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 - 0.000000000000000000000001011 104.0
SHD1_k127_4170876_6 acr, cog1993 K09137 - - 0.0000000000000000000003416 99.0
SHD1_k127_4198704_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 450.0
SHD1_k127_4198704_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000004966 231.0
SHD1_k127_4198704_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000002969 190.0
SHD1_k127_4198704_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000006711 132.0
SHD1_k127_421058_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1139.0
SHD1_k127_421058_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 2.308e-306 944.0
SHD1_k127_4228296_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1528.0
SHD1_k127_4228296_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 505.0
SHD1_k127_4228296_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 501.0
SHD1_k127_4228296_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 389.0
SHD1_k127_4228296_4 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 285.0
SHD1_k127_4228296_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000006106 138.0
SHD1_k127_4228730_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 349.0
SHD1_k127_4228730_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 350.0
SHD1_k127_4228730_10 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000001108 198.0
SHD1_k127_4228730_11 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000003123 187.0
SHD1_k127_4228730_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000004503 171.0
SHD1_k127_4228730_13 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000001896 153.0
SHD1_k127_4228730_14 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000005405 147.0
SHD1_k127_4228730_15 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000003267 149.0
SHD1_k127_4228730_16 energy transducer activity K03646,K03832 - - 0.0000000000001741 79.0
SHD1_k127_4228730_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 345.0
SHD1_k127_4228730_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 327.0
SHD1_k127_4228730_4 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 298.0
SHD1_k127_4228730_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 273.0
SHD1_k127_4228730_6 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000002001 235.0
SHD1_k127_4228730_7 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001133 231.0
SHD1_k127_4228730_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000004379 225.0
SHD1_k127_4228730_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000003722 199.0
SHD1_k127_4230460_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 414.0
SHD1_k127_4230460_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 377.0
SHD1_k127_4230460_2 Flavodoxin-like fold K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001281 274.0
SHD1_k127_4230460_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
SHD1_k127_4230460_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
SHD1_k127_4230460_5 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000006648 192.0
SHD1_k127_4230460_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000004599 184.0
SHD1_k127_4230460_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000007789 153.0
SHD1_k127_4230460_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000157 136.0
SHD1_k127_4230460_9 Sulfurtransferase TusA - - - 0.000000000000000000000003548 104.0
SHD1_k127_4236488_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 4.334e-288 893.0
SHD1_k127_4236488_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
SHD1_k127_4236488_2 Histidine kinase-like ATPases - - - 0.00000000005817 74.0
SHD1_k127_4236488_3 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.00003671 55.0
SHD1_k127_4244000_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 489.0
SHD1_k127_4244000_1 PFAM glycoside hydrolase 15-related K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 311.0
SHD1_k127_4244000_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 292.0
SHD1_k127_4244000_3 sequence-specific DNA binding - - - 0.0000001186 53.0
SHD1_k127_4244000_4 Copper resistance protein CopZ K07213 - - 0.00002072 49.0
SHD1_k127_4252614_0 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 332.0
SHD1_k127_4252614_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006864 258.0
SHD1_k127_4252614_3 Belongs to the universal stress protein A family - - - 0.00000000000000000000000005085 114.0
SHD1_k127_4252614_4 Transglycosylase SLT domain - - - 0.00000000008827 71.0
SHD1_k127_4252614_5 Protein of unknown function (DUF2934) - - - 0.0000001182 59.0
SHD1_k127_4255496_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 559.0
SHD1_k127_4255496_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000002497 230.0
SHD1_k127_4255496_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000006047 90.0
SHD1_k127_4258954_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.001e-211 672.0
SHD1_k127_4258954_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 497.0
SHD1_k127_4258954_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000001742 100.0
SHD1_k127_429876_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 441.0
SHD1_k127_429876_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 325.0
SHD1_k127_429876_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001435 259.0
SHD1_k127_429876_3 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.000000000000000000000000000000000000000000000000004222 190.0
SHD1_k127_4311389_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 532.0
SHD1_k127_4311389_1 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 516.0
SHD1_k127_4311389_10 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000739 103.0
SHD1_k127_4311389_11 Transcription factor zinc-finger - - - 0.000000000000000000028 100.0
SHD1_k127_4311389_12 PAS fold - - - 0.00001756 47.0
SHD1_k127_4311389_2 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 352.0
SHD1_k127_4311389_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 285.0
SHD1_k127_4311389_4 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003871 265.0
SHD1_k127_4311389_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005022 244.0
SHD1_k127_4311389_6 Pas domain s-box - - - 0.0000000000000000000000000000000000000000000000000000000000000000007928 249.0
SHD1_k127_4311389_7 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000007944 167.0
SHD1_k127_4311389_8 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000007043 162.0
SHD1_k127_4313566_0 Sigma-54 interaction domain - - - 1.087e-241 758.0
SHD1_k127_4313566_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 543.0
SHD1_k127_4313566_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 374.0
SHD1_k127_4313566_3 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000003608 117.0
SHD1_k127_4324090_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.411e-217 697.0
SHD1_k127_4324090_1 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000004427 155.0
SHD1_k127_4324090_2 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000001686 110.0
SHD1_k127_4324090_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000002738 67.0
SHD1_k127_4335718_0 PD-(D/E)XK nuclease superfamily - - - 7.303e-240 775.0
SHD1_k127_4342274_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.139e-228 715.0
SHD1_k127_4342274_1 family UPF0324 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 583.0
SHD1_k127_4342274_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000001496 98.0
SHD1_k127_4342274_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000001009 98.0
SHD1_k127_4342274_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000007749 64.0
SHD1_k127_4342274_2 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
SHD1_k127_4342274_3 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 503.0
SHD1_k127_4342274_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 499.0
SHD1_k127_4342274_5 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 391.0
SHD1_k127_4342274_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000001635 252.0
SHD1_k127_4342274_7 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000000000001635 202.0
SHD1_k127_4342274_8 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000001413 186.0
SHD1_k127_4342274_9 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000005146 167.0
SHD1_k127_4347920_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 6.641e-257 809.0
SHD1_k127_4347920_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.583e-228 722.0
SHD1_k127_4347920_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 317.0
SHD1_k127_4347920_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000154 253.0
SHD1_k127_4347920_12 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
SHD1_k127_4347920_13 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000006389 226.0
SHD1_k127_4347920_14 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000001025 199.0
SHD1_k127_4347920_15 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000001208 162.0
SHD1_k127_4347920_16 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000002258 110.0
SHD1_k127_4347920_17 nucleotidyltransferase activity K07075 - - 0.000000000000000000000001022 111.0
SHD1_k127_4347920_18 - - - - 0.0000000000000000000006546 100.0
SHD1_k127_4347920_19 Domain of unknown function (DUF1858) - - - 0.0000000000000000005184 88.0
SHD1_k127_4347920_2 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 1.31e-208 659.0
SHD1_k127_4347920_21 4Fe-4S binding domain - - - 0.00002308 50.0
SHD1_k127_4347920_3 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 537.0
SHD1_k127_4347920_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 509.0
SHD1_k127_4347920_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 433.0
SHD1_k127_4347920_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 406.0
SHD1_k127_4347920_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 381.0
SHD1_k127_4347920_8 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 351.0
SHD1_k127_4347920_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 325.0
SHD1_k127_4352678_0 Belongs to the helicase family. UvrD subfamily - - - 8.658e-227 734.0
SHD1_k127_4352678_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 447.0
SHD1_k127_4352678_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000002518 151.0
SHD1_k127_4352678_3 PD-(D/E)XK nuclease superfamily - - - 0.0000001772 54.0
SHD1_k127_4353589_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.035e-288 893.0
SHD1_k127_4353589_1 Conserved region in glutamate synthase - - - 1.013e-272 846.0
SHD1_k127_4353589_10 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000001798 126.0
SHD1_k127_4353589_11 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.000000000000000000000000000002156 123.0
SHD1_k127_4353589_12 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.000000000000000000000002359 113.0
SHD1_k127_4353589_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000001582 102.0
SHD1_k127_4353589_14 - - - - 0.0000000000006492 72.0
SHD1_k127_4353589_15 serine threonine protein kinase K12132 - 2.7.11.1 0.000000001386 70.0
SHD1_k127_4353589_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
SHD1_k127_4353589_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 477.0
SHD1_k127_4353589_4 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 391.0
SHD1_k127_4353589_5 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 385.0
SHD1_k127_4353589_6 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 383.0
SHD1_k127_4353589_7 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 302.0
SHD1_k127_4353589_8 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000005355 183.0
SHD1_k127_4353589_9 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K01442 - 3.5.1.24 0.00000000000000000000000000000000000002711 155.0
SHD1_k127_4382630_0 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 415.0
SHD1_k127_4382630_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 396.0
SHD1_k127_4382630_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 320.0
SHD1_k127_4382630_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000169 149.0
SHD1_k127_4387478_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.103e-277 862.0
SHD1_k127_4387478_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.183e-215 677.0
SHD1_k127_4387478_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 521.0
SHD1_k127_4387478_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 356.0
SHD1_k127_4389094_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 578.0
SHD1_k127_4389094_1 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 477.0
SHD1_k127_4389094_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 436.0
SHD1_k127_4389094_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 361.0
SHD1_k127_4389094_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000008022 203.0
SHD1_k127_4389094_5 Erythromycin esterase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000006127 202.0
SHD1_k127_4389094_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000001979 166.0
SHD1_k127_4392084_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.054e-194 612.0
SHD1_k127_4392084_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 327.0
SHD1_k127_4392084_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004264 281.0
SHD1_k127_4392084_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000002213 207.0
SHD1_k127_4392084_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002999 178.0
SHD1_k127_4392084_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001229 130.0
SHD1_k127_4392084_6 Ribosomal protein L36 K02919 - - 0.0000000000000009021 76.0
SHD1_k127_4392084_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000101 54.0
SHD1_k127_4404718_0 GTP-binding protein TypA K06207 - - 2.372e-264 826.0
SHD1_k127_4404718_1 NADH-quinone oxidoreductase K00341 - 1.6.5.3 7.107e-244 768.0
SHD1_k127_4404718_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
SHD1_k127_4404718_11 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000001164 238.0
SHD1_k127_4404718_12 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000176 219.0
SHD1_k127_4404718_13 Signal transduction histidine kinase, nitrogen specific K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000246 192.0
SHD1_k127_4404718_15 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000001209 172.0
SHD1_k127_4404718_16 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000436 167.0
SHD1_k127_4404718_17 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000004617 160.0
SHD1_k127_4404718_18 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000004017 153.0
SHD1_k127_4404718_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000003435 145.0
SHD1_k127_4404718_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 610.0
SHD1_k127_4404718_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000001099 125.0
SHD1_k127_4404718_21 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000005429 93.0
SHD1_k127_4404718_22 - - - - 0.0001385 46.0
SHD1_k127_4404718_24 - - - - 0.000359 49.0
SHD1_k127_4404718_3 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 548.0
SHD1_k127_4404718_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 453.0
SHD1_k127_4404718_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 433.0
SHD1_k127_4404718_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 419.0
SHD1_k127_4404718_7 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 413.0
SHD1_k127_4404718_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 412.0
SHD1_k127_4404718_9 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 378.0
SHD1_k127_4405759_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.956e-278 887.0
SHD1_k127_4405759_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 340.0
SHD1_k127_4405759_2 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009883 284.0
SHD1_k127_4405759_3 SurA N-terminal domain K03769 - 5.2.1.8 0.000007811 56.0
SHD1_k127_4405850_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1096.0
SHD1_k127_4405850_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 509.0
SHD1_k127_4405850_10 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000002548 156.0
SHD1_k127_4405850_11 Thioredoxin-like - - - 0.00000000000000000000000000000000001142 141.0
SHD1_k127_4405850_12 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000004971 112.0
SHD1_k127_4405850_13 - - - - 0.00000886 48.0
SHD1_k127_4405850_2 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
SHD1_k127_4405850_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 394.0
SHD1_k127_4405850_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 349.0
SHD1_k127_4405850_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 296.0
SHD1_k127_4405850_6 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002253 235.0
SHD1_k127_4405850_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000008656 187.0
SHD1_k127_4405850_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000005203 186.0
SHD1_k127_4405850_9 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000003575 154.0
SHD1_k127_446121_0 Protein involved in outer membrane biogenesis - - - 7.576e-252 814.0
SHD1_k127_446121_1 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 296.0
SHD1_k127_446121_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
SHD1_k127_4465854_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 534.0
SHD1_k127_4465854_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 396.0
SHD1_k127_4465854_2 Cys/Met metabolism PLP-dependent enzyme K01760,K01761 - 4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 370.0
SHD1_k127_4465854_3 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006154 280.0
SHD1_k127_4465854_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000001824 188.0
SHD1_k127_4465854_5 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000005414 102.0
SHD1_k127_4465854_6 PFAM 4Fe-4S K00176 - 1.2.7.3 0.00000000000000000005189 91.0
SHD1_k127_4475181_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004723 281.0
SHD1_k127_4475181_1 denitrification pathway - - - 0.00000000000000000000000000001933 124.0
SHD1_k127_4475181_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000008507 51.0
SHD1_k127_4475181_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000009855 57.0
SHD1_k127_4475181_4 NHL repeat containing protein - - - 0.0002481 49.0
SHD1_k127_4493515_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 473.0
SHD1_k127_4493515_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003124 267.0
SHD1_k127_4493515_2 dUTP biosynthetic process K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000004434 250.0
SHD1_k127_4493515_3 Pyridoxamine 5'-phosphate - - - 0.0000000008363 60.0
SHD1_k127_4493515_4 Putative regulatory protein - - - 0.0000005352 53.0
SHD1_k127_4493515_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00008963 47.0
SHD1_k127_4499963_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 1.739e-225 721.0
SHD1_k127_4558075_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.944e-223 700.0
SHD1_k127_4558075_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 9.93e-200 632.0
SHD1_k127_4558075_10 YtxH-like protein - - - 0.0000000000000000000000001584 109.0
SHD1_k127_4558075_11 SMART Rhodanese domain protein - - - 0.0000000000000000000000005871 106.0
SHD1_k127_4558075_12 peptidyl-tyrosine sulfation - - - 0.00000000009095 71.0
SHD1_k127_4558075_14 - - - - 0.00009946 53.0
SHD1_k127_4558075_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 434.0
SHD1_k127_4558075_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 420.0
SHD1_k127_4558075_4 S-methyl-5-thioadenosine phosphorylase activity K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 328.0
SHD1_k127_4558075_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 307.0
SHD1_k127_4558075_6 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 303.0
SHD1_k127_4558075_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 294.0
SHD1_k127_4558075_8 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000004001 193.0
SHD1_k127_4558075_9 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000000006919 128.0
SHD1_k127_4559267_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 410.0
SHD1_k127_4559267_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 336.0
SHD1_k127_4559267_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001307 248.0
SHD1_k127_4559267_3 iron-sulfur cluster assembly - - - 0.000000000000000000000001907 104.0
SHD1_k127_4559267_4 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.00000000000000000000002516 100.0
SHD1_k127_4559267_5 TIGRFAM desulfoferrodoxin FeS4 iron-binding domain K05919 - 1.15.1.2 0.000000003542 58.0
SHD1_k127_4559267_6 PFAM Cobalt transport protein K16785 - - 0.00008145 53.0
SHD1_k127_4562636_0 Chemotaxis sensory transducer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004097 272.0
SHD1_k127_4562636_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003692 251.0
SHD1_k127_4562636_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000001639 78.0
SHD1_k127_4675874_0 PFAM Radical SAM - - - 5.061e-212 669.0
SHD1_k127_4675874_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 580.0
SHD1_k127_4675874_10 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000004157 159.0
SHD1_k127_4675874_11 gas vesicle protein - - - 0.0000000000000000001047 93.0
SHD1_k127_4675874_12 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000009756 84.0
SHD1_k127_4675874_13 Universal stress protein A-like protein - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00002216 53.0
SHD1_k127_4675874_2 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 402.0
SHD1_k127_4675874_3 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 363.0
SHD1_k127_4675874_4 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 304.0
SHD1_k127_4675874_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
SHD1_k127_4675874_6 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000000003091 204.0
SHD1_k127_4675874_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000004424 174.0
SHD1_k127_4675874_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000365 171.0
SHD1_k127_4675874_9 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000006464 166.0
SHD1_k127_468906_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 511.0
SHD1_k127_468906_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 481.0
SHD1_k127_468906_2 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000001002 198.0
SHD1_k127_468906_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000008292 191.0
SHD1_k127_468906_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000003108 123.0
SHD1_k127_468906_5 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000009218 121.0
SHD1_k127_468906_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000003759 74.0
SHD1_k127_4744867_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
SHD1_k127_4744867_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
SHD1_k127_4744867_2 - - - - 0.00000000000000000000000000000000000000000000000000001419 208.0
SHD1_k127_4744867_3 - - - - 0.000000000000000000000000000000000000005054 151.0
SHD1_k127_4744867_5 Cytochrome c - - - 0.0000000000000000002246 102.0
SHD1_k127_4744867_6 PFAM blue (type 1) copper domain protein - - - 0.0000000000001107 81.0
SHD1_k127_4750395_0 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 298.0
SHD1_k127_4750395_1 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 292.0
SHD1_k127_4750395_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005193 286.0
SHD1_k127_4750395_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000000000000000000000000000000000000002163 227.0
SHD1_k127_4750395_4 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000003228 221.0
SHD1_k127_4750395_5 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000001313 149.0
SHD1_k127_4750395_6 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000003812 121.0
SHD1_k127_4750395_7 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000003643 71.0
SHD1_k127_4824109_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1235.0
SHD1_k127_4824109_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 494.0
SHD1_k127_4824109_10 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000002221 151.0
SHD1_k127_4824109_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000004414 114.0
SHD1_k127_4824109_12 - - - - 0.00000000000000005189 87.0
SHD1_k127_4824109_2 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 458.0
SHD1_k127_4824109_3 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 369.0
SHD1_k127_4824109_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 358.0
SHD1_k127_4824109_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 321.0
SHD1_k127_4824109_6 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 285.0
SHD1_k127_4824109_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001013 271.0
SHD1_k127_4824109_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000008749 190.0
SHD1_k127_4824109_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000005414 166.0
SHD1_k127_4828380_0 Sigma-54 interaction domain - - - 9.098e-212 666.0
SHD1_k127_4828380_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 405.0
SHD1_k127_4828380_2 Histidine kinase K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004183 273.0
SHD1_k127_4828380_4 methyl-accepting chemotaxis protein K03406 - - 0.000000000889 63.0
SHD1_k127_4840776_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 499.0
SHD1_k127_4840776_1 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 468.0
SHD1_k127_4840776_10 Methyltransferase domain - - - 0.00001363 56.0
SHD1_k127_4840776_11 Glycosyl transferases group 1 - - - 0.0003768 50.0
SHD1_k127_4840776_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 346.0
SHD1_k127_4840776_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 331.0
SHD1_k127_4840776_4 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001219 288.0
SHD1_k127_4840776_5 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000007959 179.0
SHD1_k127_4840776_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000004755 116.0
SHD1_k127_4840776_7 Radical SAM K22227 - - 0.0000000000000000000001289 110.0
SHD1_k127_4840776_8 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000001396 102.0
SHD1_k127_4840776_9 Bacterial membrane protein YfhO - - - 0.00000000008938 66.0
SHD1_k127_4843997_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 576.0
SHD1_k127_4843997_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 557.0
SHD1_k127_4843997_10 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000002306 93.0
SHD1_k127_4843997_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 475.0
SHD1_k127_4843997_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 376.0
SHD1_k127_4843997_4 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 366.0
SHD1_k127_4843997_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 286.0
SHD1_k127_4843997_6 Two component regulator propeller K00936 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000007232 246.0
SHD1_k127_4843997_7 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000001322 201.0
SHD1_k127_4843997_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002262 193.0
SHD1_k127_4843997_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000002906 121.0
SHD1_k127_4852216_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 309.0
SHD1_k127_4852216_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 266.0
SHD1_k127_4852216_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000001444 250.0
SHD1_k127_4852216_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003346 222.0
SHD1_k127_4871432_0 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 340.0
SHD1_k127_4871432_1 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 335.0
SHD1_k127_4871836_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.221e-293 911.0
SHD1_k127_4874750_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.265e-207 653.0
SHD1_k127_4874750_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 5.571e-205 638.0
SHD1_k127_4874750_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000002023 225.0
SHD1_k127_4874750_11 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000006386 148.0
SHD1_k127_4874750_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 570.0
SHD1_k127_4874750_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 487.0
SHD1_k127_4874750_4 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 407.0
SHD1_k127_4874750_5 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 364.0
SHD1_k127_4874750_6 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 352.0
SHD1_k127_4874750_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006102 276.0
SHD1_k127_4874750_8 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
SHD1_k127_4874750_9 PFAM phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002696 237.0
SHD1_k127_4892981_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1701.0
SHD1_k127_4892981_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.852e-281 872.0
SHD1_k127_4892981_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000001163 239.0
SHD1_k127_4892981_11 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 239.0
SHD1_k127_4892981_12 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000945 224.0
SHD1_k127_4892981_13 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000003785 202.0
SHD1_k127_4892981_14 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000005465 203.0
SHD1_k127_4892981_15 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000001274 196.0
SHD1_k127_4892981_16 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000001027 181.0
SHD1_k127_4892981_17 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000001264 150.0
SHD1_k127_4892981_18 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000004857 128.0
SHD1_k127_4892981_19 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000001818 125.0
SHD1_k127_4892981_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.773e-195 617.0
SHD1_k127_4892981_20 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000001527 114.0
SHD1_k127_4892981_21 Transcriptional regulator, arsR family - - - 0.0000000000000000000000004427 108.0
SHD1_k127_4892981_22 - - - - 0.000000000000000000000006211 108.0
SHD1_k127_4892981_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.432e-194 613.0
SHD1_k127_4892981_4 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 493.0
SHD1_k127_4892981_5 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 480.0
SHD1_k127_4892981_6 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 352.0
SHD1_k127_4892981_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003209 271.0
SHD1_k127_4892981_8 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 263.0
SHD1_k127_4892981_9 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000312 254.0
SHD1_k127_4896134_0 TonB-dependent Receptor Plug Domain - - - 0.00000000000005444 78.0
SHD1_k127_4896134_1 Belongs to the sulfur carrier protein TusA family - - - 0.0000000001746 64.0
SHD1_k127_4896134_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000004224 66.0
SHD1_k127_4896134_3 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000003497 51.0
SHD1_k127_48970_0 Heat shock 70 kDa protein K04043 - - 0.0 1019.0
SHD1_k127_48970_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 492.0
SHD1_k127_48970_10 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 290.0
SHD1_k127_48970_11 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001949 269.0
SHD1_k127_48970_12 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000005584 253.0
SHD1_k127_48970_13 PFAM SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
SHD1_k127_48970_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004926 218.0
SHD1_k127_48970_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000009332 186.0
SHD1_k127_48970_16 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000008949 177.0
SHD1_k127_48970_17 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000002737 151.0
SHD1_k127_48970_18 His Kinase A (phosphoacceptor - - - 0.00000000006993 74.0
SHD1_k127_48970_19 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000001393 64.0
SHD1_k127_48970_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 480.0
SHD1_k127_48970_20 integral membrane protein - - - 0.00000149 60.0
SHD1_k127_48970_21 PFAM amino acid-binding ACT domain protein - - - 0.00002139 53.0
SHD1_k127_48970_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 448.0
SHD1_k127_48970_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 446.0
SHD1_k127_48970_5 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 415.0
SHD1_k127_48970_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 419.0
SHD1_k127_48970_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 372.0
SHD1_k127_48970_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 356.0
SHD1_k127_48970_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 308.0
SHD1_k127_4923101_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5.499e-311 969.0
SHD1_k127_4923101_1 pathogenesis K13669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 633.0
SHD1_k127_4923101_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 396.0
SHD1_k127_4923101_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 385.0
SHD1_k127_4923101_12 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 356.0
SHD1_k127_4923101_13 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 347.0
SHD1_k127_4923101_14 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 353.0
SHD1_k127_4923101_15 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 289.0
SHD1_k127_4923101_16 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 288.0
SHD1_k127_4923101_17 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001873 285.0
SHD1_k127_4923101_18 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005015 264.0
SHD1_k127_4923101_19 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000003823 235.0
SHD1_k127_4923101_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 571.0
SHD1_k127_4923101_20 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000001646 181.0
SHD1_k127_4923101_21 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000001675 177.0
SHD1_k127_4923101_22 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000005592 151.0
SHD1_k127_4923101_23 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000004659 116.0
SHD1_k127_4923101_24 CAAX protease self-immunity K07052 - - 0.0000000003456 68.0
SHD1_k127_4923101_25 Belongs to the peptidase M48B family - - - 0.00000001974 58.0
SHD1_k127_4923101_3 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 475.0
SHD1_k127_4923101_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 429.0
SHD1_k127_4923101_5 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 425.0
SHD1_k127_4923101_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 422.0
SHD1_k127_4923101_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
SHD1_k127_4923101_8 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 400.0
SHD1_k127_4923101_9 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 394.0
SHD1_k127_4927207_0 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 494.0
SHD1_k127_4927207_1 Flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001942 268.0
SHD1_k127_4927207_2 light absorption K06893 - - 0.0000000000000000001482 91.0
SHD1_k127_4946238_0 FtsX-like permease family K02004 - - 2.413e-320 997.0
SHD1_k127_4946238_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 403.0
SHD1_k127_4946238_2 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 381.0
SHD1_k127_4946238_3 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 353.0
SHD1_k127_4960092_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 362.0
SHD1_k127_4960092_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 359.0
SHD1_k127_4960092_2 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001534 267.0
SHD1_k127_4960092_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000516 155.0
SHD1_k127_4960092_4 Domain of unknown function (DUF4382) - - - 0.00000000000000000005822 94.0
SHD1_k127_4960092_5 Cupin domain - - - 0.00000000000000002099 81.0
SHD1_k127_4960092_6 Domain of unknown function (DUF4382) - - - 0.0000003954 53.0
SHD1_k127_497268_0 DNA polymerase K02347 - - 1.28e-204 652.0
SHD1_k127_497268_1 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 444.0
SHD1_k127_497268_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004727 245.0
SHD1_k127_497268_3 DsrE/DsrF/DrsH-like family - - - 0.0000000001439 63.0
SHD1_k127_4972820_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 615.0
SHD1_k127_4972820_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
SHD1_k127_4972820_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000002104 213.0
SHD1_k127_4972820_3 HD domain K07023 - - 0.0000000000000000000000000000000000000000000008779 168.0
SHD1_k127_4972820_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000003782 75.0
SHD1_k127_4974965_0 Cytochrome b5-like Heme/Steroid binding domain K07245,K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001743 259.0
SHD1_k127_4974965_1 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005747 232.0
SHD1_k127_4983916_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 335.0
SHD1_k127_4983916_1 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000292 156.0
SHD1_k127_4983916_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000003082 127.0
SHD1_k127_4983916_3 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000005719 114.0
SHD1_k127_4983916_4 - - - - 0.0000000000000001726 82.0
SHD1_k127_4983916_5 PFAM Rubrerythrin - - - 0.000000000002635 73.0
SHD1_k127_4983916_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0007365 43.0
SHD1_k127_4987441_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1022.0
SHD1_k127_4987441_1 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 511.0
SHD1_k127_4987441_10 Dihydroneopterin aldolase - - - 0.00000000000000000000000000000000000000388 154.0
SHD1_k127_4987441_11 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000001976 154.0
SHD1_k127_4987441_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000000815 118.0
SHD1_k127_4987441_13 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000006605 99.0
SHD1_k127_4987441_14 Cytochrome c K12263 - - 0.0000000000000001945 85.0
SHD1_k127_4987441_15 Protein of unknown function (DUF1573) - - - 0.00004129 48.0
SHD1_k127_4987441_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 380.0
SHD1_k127_4987441_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 346.0
SHD1_k127_4987441_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
SHD1_k127_4987441_5 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000002775 242.0
SHD1_k127_4987441_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000008122 251.0
SHD1_k127_4987441_7 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000015 231.0
SHD1_k127_4987441_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002334 233.0
SHD1_k127_4987441_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000002171 209.0
SHD1_k127_5000332_0 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 519.0
SHD1_k127_5000332_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 396.0
SHD1_k127_5000332_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 397.0
SHD1_k127_5000332_3 membrane K09133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 338.0
SHD1_k127_5000332_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 295.0
SHD1_k127_5000332_5 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000004103 268.0
SHD1_k127_5000332_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000005963 108.0
SHD1_k127_5013867_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 3.87e-229 732.0
SHD1_k127_5013867_1 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000001737 187.0
SHD1_k127_5013867_2 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000005278 169.0
SHD1_k127_5013867_3 STAS domain - - - 0.0000008003 57.0
SHD1_k127_5035197_0 PFAM magnesium chelatase ChlI subunit K07391 - - 1.29e-207 658.0
SHD1_k127_5035197_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 490.0
SHD1_k127_5035197_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 316.0
SHD1_k127_5035197_4 Regulatory protein, FmdB family - - - 0.000000000000000002533 86.0
SHD1_k127_5035197_5 denitrification pathway K03532 - - 0.0008789 47.0
SHD1_k127_5063505_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 460.0
SHD1_k127_5063505_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000003541 196.0
SHD1_k127_5063505_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000005506 175.0
SHD1_k127_5063505_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000002484 174.0
SHD1_k127_5063505_4 - - - - 0.0000000000000000000000000001074 119.0
SHD1_k127_5063505_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005329 112.0
SHD1_k127_5063505_6 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000001942 107.0
SHD1_k127_5064337_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 604.0
SHD1_k127_5064337_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000003363 242.0
SHD1_k127_5064337_2 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000008883 172.0
SHD1_k127_5064337_3 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000007615 124.0
SHD1_k127_5088161_0 Aminotransferase class-III K01845 - 5.4.3.8 2.392e-202 637.0
SHD1_k127_5088161_1 Polysulphide reductase, NrfD - - - 1.973e-195 616.0
SHD1_k127_5088161_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 437.0
SHD1_k127_5088161_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000007308 233.0
SHD1_k127_5088161_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000005384 207.0
SHD1_k127_5088161_5 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000009716 136.0
SHD1_k127_5088161_6 heat shock protein binding - - - 0.00000000000000000000000000000000002347 147.0
SHD1_k127_5144594_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 437.0
SHD1_k127_5144594_1 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 397.0
SHD1_k127_5144594_10 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000001017 113.0
SHD1_k127_5144594_11 Fimbrial assembly protein (PilN) - - - 0.0000000001753 74.0
SHD1_k127_5144594_12 General secretion pathway protein K02457 - - 0.000000008829 64.0
SHD1_k127_5144594_13 fimbrial assembly K02461 - - 0.00000002016 67.0
SHD1_k127_5144594_14 Prokaryotic N-terminal methylation motif K02458 - - 0.000003021 54.0
SHD1_k127_5144594_15 Type II secretion system (T2SS), protein M subtype b - - - 0.000006199 56.0
SHD1_k127_5144594_16 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.0001581 52.0
SHD1_k127_5144594_17 - - - - 0.0005457 50.0
SHD1_k127_5144594_2 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 330.0
SHD1_k127_5144594_3 Peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000009107 203.0
SHD1_k127_5144594_4 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000001391 173.0
SHD1_k127_5144594_5 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000008846 167.0
SHD1_k127_5144594_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001389 153.0
SHD1_k127_5144594_8 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000001337 148.0
SHD1_k127_5144594_9 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000008278 141.0
SHD1_k127_516976_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 7.094e-292 904.0
SHD1_k127_516976_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 387.0
SHD1_k127_516976_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 297.0
SHD1_k127_516976_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006401 261.0
SHD1_k127_516976_4 NosL - - - 0.00000000000000000000000000000000000003203 149.0
SHD1_k127_516976_5 - - - - 0.00000000000001092 77.0
SHD1_k127_5182454_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 531.0
SHD1_k127_5182454_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 445.0
SHD1_k127_5182454_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000388 226.0
SHD1_k127_5182454_3 diguanylate cyclase - - - 0.000000000000000000000000000000004773 147.0
SHD1_k127_5220421_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 355.0
SHD1_k127_5220421_1 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000001026 218.0
SHD1_k127_5220421_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000005748 184.0
SHD1_k127_5220421_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000003303 171.0
SHD1_k127_5223097_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000006592 203.0
SHD1_k127_5223097_1 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000003174 179.0
SHD1_k127_5223097_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000005835 167.0
SHD1_k127_5223097_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000005294 130.0
SHD1_k127_5223097_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000001331 68.0
SHD1_k127_5241832_0 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 1.442e-216 694.0
SHD1_k127_5241832_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 377.0
SHD1_k127_5241832_2 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000000000002069 164.0
SHD1_k127_5241832_3 DNA-binding protein VF530 - - - 0.000000000000000000000000000009006 119.0
SHD1_k127_5241832_4 S1 domain K00243 - - 0.0000000000000000002264 88.0
SHD1_k127_5241832_5 PilZ domain - - - 0.0002886 50.0
SHD1_k127_5241832_6 PFAM Transposase IS200 like - - - 0.0007619 44.0
SHD1_k127_5247337_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1192.0
SHD1_k127_5247337_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1130.0
SHD1_k127_5247337_10 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 310.0
SHD1_k127_5247337_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 308.0
SHD1_k127_5247337_12 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 310.0
SHD1_k127_5247337_13 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 286.0
SHD1_k127_5247337_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
SHD1_k127_5247337_15 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
SHD1_k127_5247337_16 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
SHD1_k127_5247337_17 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000008455 236.0
SHD1_k127_5247337_18 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000001069 229.0
SHD1_k127_5247337_2 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 604.0
SHD1_k127_5247337_20 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000002337 219.0
SHD1_k127_5247337_21 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000187 198.0
SHD1_k127_5247337_22 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000001775 208.0
SHD1_k127_5247337_23 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000000000000002816 180.0
SHD1_k127_5247337_24 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000063 185.0
SHD1_k127_5247337_25 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000002709 177.0
SHD1_k127_5247337_26 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000004057 148.0
SHD1_k127_5247337_27 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000007108 150.0
SHD1_k127_5247337_28 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000001135 128.0
SHD1_k127_5247337_29 cell redox homeostasis K02199 - - 0.0000000000000000000000000000000331 132.0
SHD1_k127_5247337_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 589.0
SHD1_k127_5247337_30 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000009789 126.0
SHD1_k127_5247337_31 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000001856 112.0
SHD1_k127_5247337_32 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000002715 111.0
SHD1_k127_5247337_33 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000008716 100.0
SHD1_k127_5247337_34 AI-2E family transporter - - - 0.000000000000000151 82.0
SHD1_k127_5247337_36 COG2200 FOG EAL domain K20963 - 3.1.4.52 0.000000002317 66.0
SHD1_k127_5247337_37 protein secretion K03116,K03117 - - 0.0000008588 53.0
SHD1_k127_5247337_4 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 438.0
SHD1_k127_5247337_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 402.0
SHD1_k127_5247337_6 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 366.0
SHD1_k127_5247337_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 344.0
SHD1_k127_5247337_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 349.0
SHD1_k127_5247337_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 336.0
SHD1_k127_52637_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 302.0
SHD1_k127_52637_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001376 262.0
SHD1_k127_52637_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000007427 244.0
SHD1_k127_52637_3 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000000000000000000000000000003226 202.0
SHD1_k127_52637_4 response regulator, receiver - - - 0.00000000000000000000000000000292 138.0
SHD1_k127_52637_5 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000006174 118.0
SHD1_k127_5276846_0 ABC transporter K06020 - 3.6.3.25 2.26e-295 911.0
SHD1_k127_5276846_1 NAD(P)-binding Rossmann-like domain - - - 0.000000000000003283 78.0
SHD1_k127_5280920_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 495.0
SHD1_k127_5280920_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
SHD1_k127_5280920_2 Peptidase S24-like K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000002171 209.0
SHD1_k127_5280920_3 pfam nudix - - - 0.00000000000000000000000000000000000000000000000000000005762 200.0
SHD1_k127_5280920_4 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000007639 127.0
SHD1_k127_5280920_5 Domain of unknown function (DUF4412) - - - 0.0000000000000000000001871 106.0
SHD1_k127_5280920_6 protein conserved in bacteria - - - 0.000000000000000002002 89.0
SHD1_k127_5280920_7 toxin-antitoxin pair type II binding - - - 0.00009889 48.0
SHD1_k127_5280920_8 nucleic acid-binding protein contains PIN domain - - - 0.0009765 48.0
SHD1_k127_5330311_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 528.0
SHD1_k127_5330311_1 response regulator K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 495.0
SHD1_k127_5330311_10 SdpI/YhfL protein family - - - 0.00000000000000000004554 92.0
SHD1_k127_5330311_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 480.0
SHD1_k127_5330311_3 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 359.0
SHD1_k127_5330311_4 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 351.0
SHD1_k127_5330311_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002313 252.0
SHD1_k127_5330311_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000648 201.0
SHD1_k127_5330311_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000001898 154.0
SHD1_k127_5330311_8 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000001352 146.0
SHD1_k127_5330311_9 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000001797 132.0
SHD1_k127_5399726_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.399e-240 754.0
SHD1_k127_5399726_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.82e-211 664.0
SHD1_k127_5399726_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000006066 236.0
SHD1_k127_5399726_3 PFAM Amino acid-binding ACT - - - 0.00000002525 55.0
SHD1_k127_5434626_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 4.488e-202 636.0
SHD1_k127_5434626_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.074e-198 627.0
SHD1_k127_5434626_10 metal ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
SHD1_k127_5434626_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000007136 156.0
SHD1_k127_5434626_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000003044 132.0
SHD1_k127_5434626_13 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000004392 115.0
SHD1_k127_5434626_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000003969 86.0
SHD1_k127_5434626_16 protein secretion K03116,K03117 - - 0.000000006327 59.0
SHD1_k127_5434626_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 576.0
SHD1_k127_5434626_3 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 549.0
SHD1_k127_5434626_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 495.0
SHD1_k127_5434626_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 385.0
SHD1_k127_5434626_6 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 376.0
SHD1_k127_5434626_7 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 332.0
SHD1_k127_5434626_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 304.0
SHD1_k127_5434626_9 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
SHD1_k127_5447206_0 HMGL-like K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 394.0
SHD1_k127_5447206_1 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000001255 131.0
SHD1_k127_5455318_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 2.669e-203 649.0
SHD1_k127_5455318_1 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 320.0
SHD1_k127_5473530_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 401.0
SHD1_k127_5473530_1 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007752 285.0
SHD1_k127_5473530_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000163 255.0
SHD1_k127_5473530_3 Histidine kinase K02660,K11525 - - 0.000000000000000000004305 94.0
SHD1_k127_5473530_4 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000003757 85.0
SHD1_k127_5483615_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002959 282.0
SHD1_k127_5483615_1 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
SHD1_k127_5483615_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000002094 167.0
SHD1_k127_5483615_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000001984 127.0
SHD1_k127_5483615_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001528 99.0
SHD1_k127_5483615_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000266 84.0
SHD1_k127_5500711_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 570.0
SHD1_k127_5500711_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 300.0
SHD1_k127_5500711_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000025 171.0
SHD1_k127_5500711_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000008979 121.0
SHD1_k127_5502974_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2111.0
SHD1_k127_5502974_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1877.0
SHD1_k127_5502974_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000005153 140.0
SHD1_k127_5502974_11 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000003657 128.0
SHD1_k127_5502974_12 protein kinase activity - - - 0.000000000000000000000000001809 120.0
SHD1_k127_5502974_13 12 heme-binding sites - - - 0.000000000000000000001914 96.0
SHD1_k127_5502974_14 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002461 81.0
SHD1_k127_5502974_15 Ribosomal protein L33 K02913 - - 0.0000000000002434 72.0
SHD1_k127_5502974_16 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000005997 70.0
SHD1_k127_5502974_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000008385 50.0
SHD1_k127_5502974_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 580.0
SHD1_k127_5502974_3 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 424.0
SHD1_k127_5502974_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 337.0
SHD1_k127_5502974_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
SHD1_k127_5502974_6 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002287 256.0
SHD1_k127_5502974_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000001011 212.0
SHD1_k127_5502974_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000004311 197.0
SHD1_k127_5502974_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001713 211.0
SHD1_k127_563260_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.111e-214 676.0
SHD1_k127_563260_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 313.0
SHD1_k127_563260_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 308.0
SHD1_k127_563260_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001215 260.0
SHD1_k127_563260_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
SHD1_k127_563260_5 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000006251 149.0
SHD1_k127_563260_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000127 96.0
SHD1_k127_563260_7 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000006295 103.0
SHD1_k127_563260_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000002417 88.0
SHD1_k127_563260_9 Sporulation and spore germination - - - 0.000000000000007746 82.0
SHD1_k127_58377_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.811e-222 726.0
SHD1_k127_58377_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 531.0
SHD1_k127_58377_10 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000003189 127.0
SHD1_k127_58377_11 PFAM response regulator receiver - - - 0.0000007783 59.0
SHD1_k127_58377_12 curli production assembly transport component CsgG - - - 0.0000009282 62.0
SHD1_k127_58377_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 470.0
SHD1_k127_58377_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 459.0
SHD1_k127_58377_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 423.0
SHD1_k127_58377_5 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 355.0
SHD1_k127_58377_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000003132 262.0
SHD1_k127_58377_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000005945 213.0
SHD1_k127_58377_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000002706 205.0
SHD1_k127_58377_9 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000004125 138.0
SHD1_k127_593110_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 505.0
SHD1_k127_593110_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 461.0
SHD1_k127_593110_10 COG2203 FOG GAF domain - - - 0.000004338 58.0
SHD1_k127_593110_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 421.0
SHD1_k127_593110_3 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 295.0
SHD1_k127_593110_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 252.0
SHD1_k127_593110_5 - - - - 0.000000000000000000000000000000000000000000000000000000001302 208.0
SHD1_k127_593110_6 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000001732 180.0
SHD1_k127_593110_7 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000227 164.0
SHD1_k127_593110_8 Histidine kinase A domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000001361 171.0
SHD1_k127_593110_9 Chromate resistance exported protein - - - 0.000000000000000000000000003678 111.0
SHD1_k127_59818_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 7.535e-264 837.0
SHD1_k127_59818_1 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 305.0
SHD1_k127_59818_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000002568 144.0
SHD1_k127_59818_3 - - - - 0.000000000004254 67.0
SHD1_k127_59818_4 Domain of unknown function (DUF4912) K09942 - - 0.0000001588 63.0
SHD1_k127_620797_0 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 474.0
SHD1_k127_620797_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000007771 185.0
SHD1_k127_620797_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000009644 149.0
SHD1_k127_651954_0 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 586.0
SHD1_k127_651954_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 515.0
SHD1_k127_651954_10 UTRA K03710 - - 0.0000000000000000000000000000002419 132.0
SHD1_k127_651954_11 Universal stress protein family K07090 - - 0.00000000000000000000000000001122 124.0
SHD1_k127_651954_12 Cold shock K03704 - - 0.000000000000000000000000002764 111.0
SHD1_k127_651954_14 - - - - 0.000000000000000001242 88.0
SHD1_k127_651954_15 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000409 65.0
SHD1_k127_651954_2 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 533.0
SHD1_k127_651954_3 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 461.0
SHD1_k127_651954_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 473.0
SHD1_k127_651954_5 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
SHD1_k127_651954_6 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 410.0
SHD1_k127_651954_7 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000001091 219.0
SHD1_k127_651954_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000007886 218.0
SHD1_k127_651954_9 - - - - 0.000000000000000000000000000000000000000000000000005013 184.0
SHD1_k127_659778_0 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 319.0
SHD1_k127_659778_1 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000008932 83.0
SHD1_k127_659778_2 Domain of unknown function DUF302 - - - 0.0000006786 58.0
SHD1_k127_696801_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 309.0
SHD1_k127_696801_1 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002964 251.0
SHD1_k127_696801_2 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000001917 181.0
SHD1_k127_696801_3 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000008471 134.0
SHD1_k127_696801_4 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000125 128.0
SHD1_k127_696801_5 toxin-antitoxin pair type II binding - - - 0.00000001712 57.0
SHD1_k127_696801_6 - - - - 0.00002314 47.0
SHD1_k127_707334_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 8.479e-306 955.0
SHD1_k127_707334_1 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 594.0
SHD1_k127_707334_2 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 402.0
SHD1_k127_707334_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000003865 138.0
SHD1_k127_707334_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001805 108.0
SHD1_k127_707334_5 reductase, alpha subunit K00394 - 1.8.99.2 0.0000000000006746 68.0
SHD1_k127_707999_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.985e-200 653.0
SHD1_k127_707999_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000003917 166.0
SHD1_k127_707999_2 histidine kinase HAMP region domain protein - - - 0.00000000000000008566 81.0
SHD1_k127_713125_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1285.0
SHD1_k127_713125_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.736e-268 841.0
SHD1_k127_713125_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 375.0
SHD1_k127_713125_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 378.0
SHD1_k127_713125_4 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002674 271.0
SHD1_k127_713125_5 - - - - 0.000000003954 59.0
SHD1_k127_714524_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 497.0
SHD1_k127_714524_1 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
SHD1_k127_714524_2 CHRD domain - - - 0.000000000000000000000000000000000000002564 152.0
SHD1_k127_714524_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000002543 146.0
SHD1_k127_714524_4 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000001431 130.0
SHD1_k127_714524_5 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000006323 126.0
SHD1_k127_714524_6 PQ loop repeat K15383 - - 0.000000000000000000001352 98.0
SHD1_k127_714524_7 PFAM Outer membrane efflux protein K18139 - - 0.000000000000201 70.0
SHD1_k127_714524_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000007689 53.0
SHD1_k127_726579_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 477.0
SHD1_k127_726579_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 476.0
SHD1_k127_726579_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 424.0
SHD1_k127_726579_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 319.0
SHD1_k127_726579_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002873 265.0
SHD1_k127_726579_5 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000009199 237.0
SHD1_k127_726579_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
SHD1_k127_726579_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000001262 220.0
SHD1_k127_726579_8 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000002666 184.0
SHD1_k127_726579_9 - K07092 - - 0.00008467 50.0
SHD1_k127_736160_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.223e-278 869.0
SHD1_k127_736160_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 3.39e-196 632.0
SHD1_k127_736160_10 DNA-binding transcription factor activity K18996 - - 0.0000000000000000001653 89.0
SHD1_k127_736160_11 - - - - 0.0000002514 55.0
SHD1_k127_736160_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 6.716e-195 618.0
SHD1_k127_736160_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 530.0
SHD1_k127_736160_4 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 476.0
SHD1_k127_736160_5 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 340.0
SHD1_k127_736160_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007067 274.0
SHD1_k127_736160_7 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005001 244.0
SHD1_k127_736160_8 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000003015 241.0
SHD1_k127_736160_9 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.000000000000000000000000000000000001314 144.0
SHD1_k127_743880_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.701e-203 639.0
SHD1_k127_743880_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.785e-197 619.0
SHD1_k127_743880_10 PFAM Rhodanese domain protein - - - 0.00000001873 62.0
SHD1_k127_743880_11 PFAM MOSC domain containing protein - - - 0.00000288 49.0
SHD1_k127_743880_2 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 330.0
SHD1_k127_743880_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 313.0
SHD1_k127_743880_4 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 285.0
SHD1_k127_743880_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000001211 237.0
SHD1_k127_743880_6 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000008292 197.0
SHD1_k127_743880_7 AMP binding - - - 0.00000000000000000000000000000000000000004116 157.0
SHD1_k127_743880_8 Transcriptional regulator - - - 0.00000000000000000000000000000002543 136.0
SHD1_k127_743880_9 - - - - 0.0000000000000000006593 89.0
SHD1_k127_748050_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.149e-287 903.0
SHD1_k127_748050_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 596.0
SHD1_k127_748050_10 Pilus assembly protein, PilP K02665 - - 0.00000000001501 71.0
SHD1_k127_748050_11 Pilus assembly protein, PilO K02664 - - 0.000000003 65.0
SHD1_k127_748050_12 PFAM Fimbrial assembly K02663 - - 0.00000005216 61.0
SHD1_k127_748050_13 PFAM type II and III secretion system protein K02666 - - 0.0003055 52.0
SHD1_k127_748050_2 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 343.0
SHD1_k127_748050_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 323.0
SHD1_k127_748050_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
SHD1_k127_748050_5 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000009173 250.0
SHD1_k127_748050_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000003633 234.0
SHD1_k127_748050_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002832 108.0
SHD1_k127_748050_8 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001014 89.0
SHD1_k127_748050_9 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000008019 90.0
SHD1_k127_748829_0 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 400.0
SHD1_k127_748829_1 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
SHD1_k127_748829_2 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000001888 217.0
SHD1_k127_748829_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000002517 209.0
SHD1_k127_748829_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000006045 181.0
SHD1_k127_748829_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000007809 151.0
SHD1_k127_748829_6 Dienelactone hydrolase family - - - 0.00000000000000000000000000007504 116.0
SHD1_k127_755547_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 520.0
SHD1_k127_755547_1 CAAX protease self-immunity K07052 - - 0.0000000000002624 69.0
SHD1_k127_765700_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.02e-260 814.0
SHD1_k127_765700_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000004891 229.0
SHD1_k127_765700_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000008403 209.0
SHD1_k127_765700_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001396 207.0
SHD1_k127_765700_4 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000001546 175.0
SHD1_k127_765700_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000138 158.0
SHD1_k127_765700_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000162 71.0
SHD1_k127_765700_7 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000002333 70.0
SHD1_k127_765700_8 - K06039,K07092 - - 0.000001114 55.0
SHD1_k127_765700_9 Bacterial regulatory protein, Fis family - - - 0.00002283 49.0
SHD1_k127_772912_0 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 443.0
SHD1_k127_772912_1 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 323.0
SHD1_k127_772912_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007471 288.0
SHD1_k127_772912_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000004806 228.0
SHD1_k127_772912_4 nucleoside-triphosphate diphosphatase activity K06287 - - 0.00000000000000000000000000000000000000000000000006973 184.0
SHD1_k127_772912_5 metalloendopeptidase activity K03799 - - 0.00000000000000000000000006323 119.0
SHD1_k127_790977_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 2.114e-243 774.0
SHD1_k127_790977_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.063e-207 661.0
SHD1_k127_790977_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.278e-196 617.0
SHD1_k127_790977_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 602.0
SHD1_k127_790977_4 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 321.0
SHD1_k127_790977_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002958 244.0
SHD1_k127_790977_6 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000002225 139.0
SHD1_k127_790977_7 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000001958 137.0
SHD1_k127_800186_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 453.0
SHD1_k127_800186_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 340.0
SHD1_k127_800186_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000006662 248.0
SHD1_k127_800186_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001894 233.0
SHD1_k127_800186_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000001483 233.0
SHD1_k127_800186_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000001513 174.0
SHD1_k127_800186_6 Universal stress protein family - - - 0.0000000000000000000000000000000000000005794 156.0
SHD1_k127_800186_7 energy transducer activity K03832 - - 0.0000000000000000000000000000000000001239 153.0
SHD1_k127_800186_8 proteolysis K03665 - - 0.00000000000000000000000000002775 123.0
SHD1_k127_800186_9 - - - - 0.000002525 49.0
SHD1_k127_809900_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1956.0
SHD1_k127_809900_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 353.0
SHD1_k127_809900_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 305.0
SHD1_k127_809900_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 308.0
SHD1_k127_809900_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000004483 228.0
SHD1_k127_809900_5 PFAM CBS domain - - - 0.0000000000000000000000000000007063 130.0
SHD1_k127_809900_6 Putative regulatory protein - - - 0.0000000000000000000005189 98.0
SHD1_k127_813422_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 7.509e-267 833.0
SHD1_k127_813422_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 4.019e-241 763.0
SHD1_k127_813422_10 - - - - 0.000000000000000000000000000000000000000000000000000000000001714 221.0
SHD1_k127_813422_11 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000005845 192.0
SHD1_k127_813422_12 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000000143 189.0
SHD1_k127_813422_13 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000003516 142.0
SHD1_k127_813422_14 MlaC protein K07323 - - 0.0000000000000000000000000000000002862 139.0
SHD1_k127_813422_15 PFAM RNA recognition motif - - - 0.00000000000000000000001388 105.0
SHD1_k127_813422_16 EamA-like transporter family - - - 0.000000000000000003657 91.0
SHD1_k127_813422_17 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000006062 78.0
SHD1_k127_813422_18 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.00000000000941 74.0
SHD1_k127_813422_19 Uncharacterised protein family UPF0047 - - - 0.000003781 49.0
SHD1_k127_813422_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 566.0
SHD1_k127_813422_3 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 564.0
SHD1_k127_813422_4 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 411.0
SHD1_k127_813422_5 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 394.0
SHD1_k127_813422_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 376.0
SHD1_k127_813422_7 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001831 281.0
SHD1_k127_813422_8 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001359 269.0
SHD1_k127_813422_9 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002828 262.0
SHD1_k127_823657_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 313.0
SHD1_k127_823657_1 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.0006926 49.0
SHD1_k127_837108_0 Aminotransferase class I and II K14261 - - 1.829e-213 671.0
SHD1_k127_837108_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 602.0
SHD1_k127_837108_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000007969 203.0
SHD1_k127_837108_11 Nitroreductase family - - - 0.000000000000000000000000000000006757 136.0
SHD1_k127_837108_12 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000007043 119.0
SHD1_k127_837108_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000001181 120.0
SHD1_k127_837108_14 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001245 107.0
SHD1_k127_837108_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 539.0
SHD1_k127_837108_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 408.0
SHD1_k127_837108_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 329.0
SHD1_k127_837108_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 329.0
SHD1_k127_837108_6 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
SHD1_k127_837108_7 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
SHD1_k127_837108_8 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
SHD1_k127_837108_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000169 209.0
SHD1_k127_859779_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 597.0
SHD1_k127_859779_1 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 490.0
SHD1_k127_859779_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000003283 78.0
SHD1_k127_859779_3 sulfuric ester hydrolase activity K03760,K19353 - 2.7.8.43 0.0000000000003004 76.0
SHD1_k127_860040_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1090.0
SHD1_k127_860040_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 5.759e-256 804.0
SHD1_k127_860040_2 Sodium:solute symporter family K14393 - - 3.536e-197 630.0
SHD1_k127_860040_3 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000001449 230.0
SHD1_k127_860040_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000394 146.0
SHD1_k127_860040_5 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000003881 117.0
SHD1_k127_867347_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 571.0
SHD1_k127_867347_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 499.0
SHD1_k127_867347_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 316.0
SHD1_k127_867347_3 Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000008313 227.0
SHD1_k127_867347_4 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000001415 180.0
SHD1_k127_867347_5 Mo-molybdopterin cofactor metabolic process K02379 - - 0.0000000000000000000000000000000000003364 142.0
SHD1_k127_867347_6 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000001971 129.0
SHD1_k127_867347_7 Protein of unknown function (DUF1573) - - - 0.0000000000003281 78.0
SHD1_k127_871003_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 467.0
SHD1_k127_871003_1 Universal stress protein family - - - 0.000000002665 65.0
SHD1_k127_876494_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 526.0
SHD1_k127_876494_1 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000000005288 191.0
SHD1_k127_876494_2 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000001147 121.0
SHD1_k127_876494_3 HEAT-like repeat - - - 0.00000000000000000000003122 109.0
SHD1_k127_876494_4 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000001032 89.0
SHD1_k127_876494_5 lyase activity - - - 0.0000000000000000004063 91.0
SHD1_k127_877538_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.924e-285 889.0
SHD1_k127_877538_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.847e-227 715.0
SHD1_k127_877538_10 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000003516 158.0
SHD1_k127_877538_11 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000002156 132.0
SHD1_k127_877538_12 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000002997 109.0
SHD1_k127_877538_13 DNA-damage-inducible protein d K14623 - - 0.00000000000000000000000739 103.0
SHD1_k127_877538_14 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000001665 98.0
SHD1_k127_877538_15 Tetratricopeptide repeat protein - - - 0.0002943 51.0
SHD1_k127_877538_2 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 542.0
SHD1_k127_877538_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 525.0
SHD1_k127_877538_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 524.0
SHD1_k127_877538_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 419.0
SHD1_k127_877538_6 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 362.0
SHD1_k127_877538_7 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
SHD1_k127_877538_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008045 251.0
SHD1_k127_877538_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000003758 160.0
SHD1_k127_892947_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 458.0
SHD1_k127_892947_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 450.0
SHD1_k127_892947_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000031 258.0
SHD1_k127_892947_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004413 252.0
SHD1_k127_892947_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000113 226.0
SHD1_k127_892947_5 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000008191 213.0
SHD1_k127_892947_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000001389 201.0
SHD1_k127_892947_7 YGGT family K02221 - - 0.00000000000000000000000000000004231 128.0
SHD1_k127_892947_8 Conserved hypothetical protein 698 - - - 0.000000000000001872 88.0
SHD1_k127_902798_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.204e-286 895.0
SHD1_k127_902798_1 Dehydratase family K01687 - 4.2.1.9 3.607e-264 824.0
SHD1_k127_902798_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 456.0
SHD1_k127_902798_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 381.0
SHD1_k127_902798_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 391.0
SHD1_k127_902798_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 319.0
SHD1_k127_902798_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000144 255.0
SHD1_k127_902798_7 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000005493 148.0
SHD1_k127_902798_8 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001177 128.0
SHD1_k127_902798_9 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000008201 88.0
SHD1_k127_926169_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 559.0
SHD1_k127_926169_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 509.0
SHD1_k127_926169_2 metal-dependent enzyme K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 298.0
SHD1_k127_926169_3 PFAM HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 268.0
SHD1_k127_926169_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001246 265.0
SHD1_k127_926169_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
SHD1_k127_926169_6 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000002168 197.0
SHD1_k127_926169_7 Binds the 23S rRNA K02909 - - 0.00000000000000000000000002805 109.0
SHD1_k127_926169_8 PEP-CTERM motif - - - 0.0002535 46.0
SHD1_k127_926169_9 PFAM Uncharacterised protein family UPF0150 - - - 0.0002689 46.0
SHD1_k127_946942_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 603.0
SHD1_k127_946942_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 503.0
SHD1_k127_946942_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000001938 185.0
SHD1_k127_946942_11 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000001732 111.0
SHD1_k127_946942_12 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000001692 99.0
SHD1_k127_946942_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 477.0
SHD1_k127_946942_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.3.1.12,1.3.1.43,2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 441.0
SHD1_k127_946942_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 434.0
SHD1_k127_946942_5 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 434.0
SHD1_k127_946942_6 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 414.0
SHD1_k127_946942_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 321.0
SHD1_k127_946942_8 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 318.0
SHD1_k127_946942_9 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000006214 266.0
SHD1_k127_957565_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 2.006e-290 902.0
SHD1_k127_957565_1 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 460.0
SHD1_k127_957565_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.000000000000000000003864 98.0
SHD1_k127_957565_11 Response regulator receiver domain K03413 - - 0.0000001999 61.0
SHD1_k127_957565_2 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 303.0
SHD1_k127_957565_3 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009967 284.0
SHD1_k127_957565_4 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 271.0
SHD1_k127_957565_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008788 248.0
SHD1_k127_957565_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003471 233.0
SHD1_k127_957565_7 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000007167 154.0
SHD1_k127_957565_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000004925 135.0
SHD1_k127_957565_9 Protein of unknown function (DUF1189) - - - 0.000000000000000000001424 104.0
SHD1_k127_962614_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1164.0
SHD1_k127_962614_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
SHD1_k127_962614_10 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000006442 104.0
SHD1_k127_962614_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000001287 59.0
SHD1_k127_962614_12 DsrE/DsrF-like family - - - 0.00000001203 56.0
SHD1_k127_962614_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 443.0
SHD1_k127_962614_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 370.0
SHD1_k127_962614_4 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 353.0
SHD1_k127_962614_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 320.0
SHD1_k127_962614_6 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 300.0
SHD1_k127_962614_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000003528 229.0
SHD1_k127_962614_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000006375 127.0
SHD1_k127_962614_9 Stage II sporulation protein M - - - 0.0000000000000000000000000007508 120.0
SHD1_k127_962704_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1116.0
SHD1_k127_962704_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 376.0
SHD1_k127_962704_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000007599 221.0
SHD1_k127_962704_4 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000005675 74.0
SHD1_k127_962704_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000001629 81.0
SHD1_k127_962704_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000004044 64.0
SHD1_k127_962704_7 DsrE/DsrF-like family - - - 0.00000001203 56.0
SHD1_k127_973042_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.103e-204 646.0
SHD1_k127_973042_1 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 427.0
SHD1_k127_973042_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000005806 197.0
SHD1_k127_973042_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000009305 154.0
SHD1_k127_973042_4 Lysin motif - - - 0.00000000000000000000000000000000000005015 155.0
SHD1_k127_973042_5 lyase activity - - - 0.000000000000000000001134 95.0
SHD1_k127_98114_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 374.0
SHD1_k127_98114_1 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001127 284.0
SHD1_k127_98114_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000006715 80.0
SHD1_k127_98114_3 Vitamin K epoxide reductase family - - - 0.000000009245 61.0
SHD1_k127_981457_0 Glycosyl transferase family 2 K00721,K20534 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 439.0
SHD1_k127_981457_1 GDP-mannose 4,6 dehydratase K19180 - 1.1.1.339 0.000000000000000000000000000000000000000000000000000000000000000000001677 242.0
SHD1_k127_981457_2 methyltransferase K16215 - 2.1.1.243 0.0000000000000000000000000000000000000001853 158.0