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Overview

ID MAG03374
Name SHD2_bin.14
Sample SMP0083
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Syntrophia
Order Syntrophales
Family UBA2192
Genus UBA2192
Species
Assembly information
Completeness (%) 96.87
Contamination (%) 5.52
GC content (%) 60.0
N50 (bp) 16,840
Genome size (bp) 3,028,583

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2750

Gene name Description KEGG GOs EC E-value Score Sequence
SHD2_k127_1037151_0 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008634 255.0
SHD2_k127_1039751_0 Flagella basal body rod protein K02396 - - 0.000000000000000000000000000000000000000000000000000000454 204.0
SHD2_k127_1039751_1 Flagellar P-ring protein K02394 - - 0.00000000000000000000000000000000000000000001451 164.0
SHD2_k127_1039751_3 Rod binding protein K02395 - - 0.00000000000000000153 90.0
SHD2_k127_1039751_4 Anti-sigma-28 factor, FlgM K02398 - - 0.000000001611 63.0
SHD2_k127_1041953_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 475.0
SHD2_k127_1041953_1 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 370.0
SHD2_k127_1041953_2 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
SHD2_k127_1041953_3 Histidine kinase K00936,K07315 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000004123 181.0
SHD2_k127_1041953_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000003656 83.0
SHD2_k127_1041953_5 Pfam Response regulator receiver - - - 0.000000007117 68.0
SHD2_k127_1072818_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 574.0
SHD2_k127_1072818_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 453.0
SHD2_k127_1072818_10 - - - - 0.00003588 48.0
SHD2_k127_1072818_2 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 370.0
SHD2_k127_1072818_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007136 256.0
SHD2_k127_1072818_4 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000003313 226.0
SHD2_k127_1072818_5 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000002908 239.0
SHD2_k127_1072818_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000001395 211.0
SHD2_k127_1072818_7 FemAB family - - - 0.000000000000000000000000000000000000000000000000000005943 203.0
SHD2_k127_1072818_8 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.000000001473 67.0
SHD2_k127_1072818_9 PhoQ Sensor - - - 0.0000003216 61.0
SHD2_k127_109702_0 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 327.0
SHD2_k127_109702_1 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000007007 193.0
SHD2_k127_109702_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000757 147.0
SHD2_k127_1107555_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.256e-240 757.0
SHD2_k127_1107555_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.186e-204 646.0
SHD2_k127_1107555_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 457.0
SHD2_k127_1107555_3 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 347.0
SHD2_k127_1107555_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000001257 190.0
SHD2_k127_1107555_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000003287 185.0
SHD2_k127_1107555_6 protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000001907 146.0
SHD2_k127_1119156_0 von Willebrand factor, type A K07114 - - 5.032e-315 979.0
SHD2_k127_1119156_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 8.944e-228 716.0
SHD2_k127_1119156_2 glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 539.0
SHD2_k127_1119156_3 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000001723 149.0
SHD2_k127_1119156_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.0000000000000007507 81.0
SHD2_k127_1132885_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1124.0
SHD2_k127_1132885_1 GTP-binding protein TypA K06207 - - 7.707e-232 734.0
SHD2_k127_1132885_10 domain protein - - - 0.0000000000000000000000000000000000000005751 153.0
SHD2_k127_1132885_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000005697 156.0
SHD2_k127_1132885_12 Membrane - - - 0.000000000000000000000000000000000002676 143.0
SHD2_k127_1132885_13 CoA binding domain K06929 - - 0.000000000000000000000000000000001441 134.0
SHD2_k127_1132885_14 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000165 118.0
SHD2_k127_1132885_15 Heavy-metal-associated domain K07213 - - 0.000000000000000009525 85.0
SHD2_k127_1132885_16 cheY-homologous receiver domain K02485 - - 0.000007932 56.0
SHD2_k127_1132885_17 Tetratricopeptide repeat - - - 0.0001209 45.0
SHD2_k127_1132885_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 575.0
SHD2_k127_1132885_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 541.0
SHD2_k127_1132885_4 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 452.0
SHD2_k127_1132885_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 382.0
SHD2_k127_1132885_6 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 376.0
SHD2_k127_1132885_7 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 346.0
SHD2_k127_1132885_8 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006781 254.0
SHD2_k127_1132885_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000007677 198.0
SHD2_k127_1137671_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 3.084e-292 925.0
SHD2_k127_1137671_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000779 229.0
SHD2_k127_1139800_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.899e-306 945.0
SHD2_k127_1139800_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 445.0
SHD2_k127_1139800_2 PFAM metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 312.0
SHD2_k127_1139800_3 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000007794 248.0
SHD2_k127_1139800_4 Methylmalonyl-CoA mutase K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000004721 235.0
SHD2_k127_1139800_5 PFAM metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000006654 166.0
SHD2_k127_1139800_6 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000001646 58.0
SHD2_k127_1161703_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.335e-205 645.0
SHD2_k127_1161703_1 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 3.214e-194 612.0
SHD2_k127_1161703_2 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 386.0
SHD2_k127_1161703_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000001521 224.0
SHD2_k127_1161703_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000002865 67.0
SHD2_k127_1161703_5 PFAM permease YjgP YjgQ family protein K07091 - - 0.000601 43.0
SHD2_k127_1171035_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 3.165e-233 732.0
SHD2_k127_1171035_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 4.551e-196 620.0
SHD2_k127_1171035_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 539.0
SHD2_k127_1171035_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000002156 113.0
SHD2_k127_1171035_4 - - - - 0.0008989 42.0
SHD2_k127_1195297_0 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 389.0
SHD2_k127_1195297_1 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 364.0
SHD2_k127_1195297_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 351.0
SHD2_k127_1195297_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000009549 117.0
SHD2_k127_1195297_4 mttA/Hcf106 family K03116,K03117 - - 0.0000000000000001033 83.0
SHD2_k127_1195297_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000105 51.0
SHD2_k127_1201372_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 389.0
SHD2_k127_1201372_1 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000001039 156.0
SHD2_k127_1201372_2 Amidase - - - 0.000000000000000000000000000000000000223 141.0
SHD2_k127_1213433_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.482e-196 633.0
SHD2_k127_1213433_1 response regulator, receiver K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 368.0
SHD2_k127_1213433_2 diguanylate cyclase - - - 0.000000000000000000000000000000000316 136.0
SHD2_k127_1213433_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000004094 123.0
SHD2_k127_1213433_4 transporter antisigma-factor antagonist STAS - - - 0.0000000000000000000000001572 109.0
SHD2_k127_1247550_0 Glycosyl transferase family group 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 451.0
SHD2_k127_1247550_1 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006277 274.0
SHD2_k127_1247550_2 Transporter, auxin efflux carrier (AEC) family protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004096 252.0
SHD2_k127_1247550_3 PFAM Polysaccharide deacetylase K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008427 252.0
SHD2_k127_1247550_4 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000008504 148.0
SHD2_k127_1247550_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000002358 132.0
SHD2_k127_1247550_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000019 105.0
SHD2_k127_1247550_7 Undecaprenyl-phosphate galactose phosphotransferase - - - 0.000000000000001443 85.0
SHD2_k127_1247550_8 PgaD-like protein K11937 - - 0.0000001982 60.0
SHD2_k127_1251394_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 438.0
SHD2_k127_1251394_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000001404 256.0
SHD2_k127_1251394_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000007836 166.0
SHD2_k127_1251394_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000003847 162.0
SHD2_k127_1251394_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000007769 90.0
SHD2_k127_1254473_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.545e-317 978.0
SHD2_k127_1254473_1 aminotransferase, class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 535.0
SHD2_k127_1254473_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 391.0
SHD2_k127_1254473_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 381.0
SHD2_k127_1254473_4 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
SHD2_k127_1254473_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002697 222.0
SHD2_k127_1254473_6 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000002631 221.0
SHD2_k127_1256550_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 9.879e-267 830.0
SHD2_k127_1256550_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 610.0
SHD2_k127_1256550_2 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 533.0
SHD2_k127_1256550_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 523.0
SHD2_k127_1256550_4 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 287.0
SHD2_k127_1256550_5 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000001431 166.0
SHD2_k127_1256550_6 Water Stress and Hypersensitive response - - - 0.00000000007154 69.0
SHD2_k127_126066_0 Elongation factor Tu domain 2 K03833 - - 2.254e-208 663.0
SHD2_k127_126066_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 516.0
SHD2_k127_126066_2 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 403.0
SHD2_k127_126066_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 295.0
SHD2_k127_126066_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000004622 208.0
SHD2_k127_126066_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000002914 200.0
SHD2_k127_126066_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000003559 151.0
SHD2_k127_1269923_0 L-lactate permease K03303 - - 1.099e-222 701.0
SHD2_k127_1269923_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 542.0
SHD2_k127_1269923_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 421.0
SHD2_k127_1269923_3 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 413.0
SHD2_k127_1269923_4 radical SAM domain protein K06937,K13309 - 4.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 377.0
SHD2_k127_1269923_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211 279.0
SHD2_k127_1269923_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 266.0
SHD2_k127_1269923_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000005778 211.0
SHD2_k127_1269923_8 Mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000006349 146.0
SHD2_k127_1269923_9 Protein of unknown function DUF72 - - - 0.000000000008008 68.0
SHD2_k127_1270241_0 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 280.0
SHD2_k127_1270241_1 HMGL-like - - - 0.000000000000000000000000000000000000000000000000000000000004941 210.0
SHD2_k127_1270241_2 Biotin-requiring enzyme - - - 0.0000000000000000001602 90.0
SHD2_k127_1270241_3 - - - - 0.0000000000000006549 78.0
SHD2_k127_1293959_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.009e-221 691.0
SHD2_k127_1293959_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 594.0
SHD2_k127_1293959_2 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 349.0
SHD2_k127_1293959_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
SHD2_k127_1321352_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 491.0
SHD2_k127_1321352_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 399.0
SHD2_k127_1321352_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 388.0
SHD2_k127_1321352_3 PFAM ThiJ PfpI K05520 - 3.5.1.124 0.000000000004365 66.0
SHD2_k127_1321352_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000888 60.0
SHD2_k127_136379_0 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 577.0
SHD2_k127_136379_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 454.0
SHD2_k127_136379_2 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 311.0
SHD2_k127_136379_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
SHD2_k127_1366437_0 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 497.0
SHD2_k127_1366437_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009081 230.0
SHD2_k127_1366437_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000003487 142.0
SHD2_k127_1366437_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0001851 48.0
SHD2_k127_1373334_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 577.0
SHD2_k127_1373334_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 313.0
SHD2_k127_1373334_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000001627 178.0
SHD2_k127_1373334_3 Helix-turn-helix domain - - - 0.0000000001229 67.0
SHD2_k127_1393702_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 408.0
SHD2_k127_1393702_1 'Molybdopterin K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 410.0
SHD2_k127_1393702_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000006321 227.0
SHD2_k127_1413361_0 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 411.0
SHD2_k127_1413361_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009109 248.0
SHD2_k127_1413361_2 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000002471 213.0
SHD2_k127_1413361_3 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000001957 81.0
SHD2_k127_14232_0 MGS-like domain K00602 - 2.1.2.3,3.5.4.10 2.53e-251 783.0
SHD2_k127_14232_1 Endoribonuclease that initiates mRNA decay K18682 - - 5.25e-235 736.0
SHD2_k127_14232_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000004933 218.0
SHD2_k127_14232_11 COG NOG14552 non supervised orthologous group - - - 0.00000000000000000000000000000000000002698 147.0
SHD2_k127_14232_12 - - - - 0.00000000000000000000000000000002936 126.0
SHD2_k127_14232_13 - - - - 0.000000000000000000000000001257 114.0
SHD2_k127_14232_14 - - - - 0.00000000000000000000006085 99.0
SHD2_k127_14232_15 - - - - 0.0000000000000000000001656 98.0
SHD2_k127_14232_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000001109 96.0
SHD2_k127_14232_17 - - - - 0.0000000000000000004122 87.0
SHD2_k127_14232_18 - - - - 0.000000000000002728 78.0
SHD2_k127_14232_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 7.143e-204 644.0
SHD2_k127_14232_20 ORF located using Blastx - - - 0.00000000000002253 74.0
SHD2_k127_14232_21 non supervised orthologous group - - - 0.00000000000009099 71.0
SHD2_k127_14232_24 - - - - 0.00000000001025 65.0
SHD2_k127_14232_27 - - - - 0.0000003463 54.0
SHD2_k127_14232_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 575.0
SHD2_k127_14232_30 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0002006 48.0
SHD2_k127_14232_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 553.0
SHD2_k127_14232_5 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 344.0
SHD2_k127_14232_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 349.0
SHD2_k127_14232_7 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 295.0
SHD2_k127_14232_8 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001143 293.0
SHD2_k127_14232_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 275.0
SHD2_k127_1470829_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.5e-323 1011.0
SHD2_k127_1470829_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.31e-316 980.0
SHD2_k127_1470829_10 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000002642 211.0
SHD2_k127_1470829_11 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000001474 201.0
SHD2_k127_1470829_12 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000001486 172.0
SHD2_k127_1470829_13 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001162 140.0
SHD2_k127_1470829_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000006012 132.0
SHD2_k127_1470829_15 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000000000001726 117.0
SHD2_k127_1470829_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000000000004003 87.0
SHD2_k127_1470829_17 Fimbrial assembly protein (PilN) K02663 - - 0.000000000001307 76.0
SHD2_k127_1470829_2 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 1.348e-207 651.0
SHD2_k127_1470829_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 587.0
SHD2_k127_1470829_4 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 569.0
SHD2_k127_1470829_5 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 426.0
SHD2_k127_1470829_6 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 389.0
SHD2_k127_1470829_7 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
SHD2_k127_1470829_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 291.0
SHD2_k127_1470829_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001009 275.0
SHD2_k127_1477595_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.73e-253 800.0
SHD2_k127_1477595_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.215e-243 767.0
SHD2_k127_1477595_10 Protein conserved in bacteria - - - 0.000000000000000000000000004573 115.0
SHD2_k127_1477595_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00033,K00616,K01810,K08300,K13810 - 1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 489.0
SHD2_k127_1477595_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 345.0
SHD2_k127_1477595_4 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 342.0
SHD2_k127_1477595_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 323.0
SHD2_k127_1477595_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001463 244.0
SHD2_k127_1477595_7 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
SHD2_k127_1477595_8 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000001325 209.0
SHD2_k127_1477595_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000005449 199.0
SHD2_k127_1489762_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 8.895e-271 849.0
SHD2_k127_1489762_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 518.0
SHD2_k127_1489762_10 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000001096 203.0
SHD2_k127_1489762_11 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000003067 202.0
SHD2_k127_1489762_12 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000008345 135.0
SHD2_k127_1489762_13 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000001979 135.0
SHD2_k127_1489762_14 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.0000000000000000000000164 107.0
SHD2_k127_1489762_17 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000005627 72.0
SHD2_k127_1489762_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 469.0
SHD2_k127_1489762_3 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 332.0
SHD2_k127_1489762_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 331.0
SHD2_k127_1489762_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 312.0
SHD2_k127_1489762_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 321.0
SHD2_k127_1489762_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 293.0
SHD2_k127_1489762_8 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000005813 249.0
SHD2_k127_1489762_9 Protein of unknown function (DUF4243) - - - 0.0000000000000000000000000000000000000000000000000000000000001761 227.0
SHD2_k127_1505559_0 PFAM carboxyl transferase K01615 - 4.1.1.70 6.494e-212 665.0
SHD2_k127_1505559_1 acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 574.0
SHD2_k127_1505559_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 471.0
SHD2_k127_1505559_3 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 386.0
SHD2_k127_1505559_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 389.0
SHD2_k127_1505559_5 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.0000000000000000000000000000000000000000000000000000000000000008882 232.0
SHD2_k127_1521377_0 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 293.0
SHD2_k127_1521377_1 - - - - 0.00000000000000000000000003726 112.0
SHD2_k127_1521377_2 Protein of unknown function (DUF3024) - - - 0.00000000000000003745 81.0
SHD2_k127_1521377_4 - - - - 0.000003391 56.0
SHD2_k127_1538108_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 311.0
SHD2_k127_1538108_1 PFAM Formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000001989 234.0
SHD2_k127_1538108_2 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000466 200.0
SHD2_k127_1538108_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000002337 188.0
SHD2_k127_1538108_4 monooxygenase activity K00688 - 2.4.1.1 0.00000000000000000000000000000000002749 141.0
SHD2_k127_1538108_5 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000004081 113.0
SHD2_k127_1538108_6 - - - - 0.0000000000000007999 82.0
SHD2_k127_154363_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.695e-214 670.0
SHD2_k127_154363_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 1.394e-201 632.0
SHD2_k127_154363_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 359.0
SHD2_k127_154363_11 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 360.0
SHD2_k127_154363_12 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 351.0
SHD2_k127_154363_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 326.0
SHD2_k127_154363_14 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 329.0
SHD2_k127_154363_15 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 293.0
SHD2_k127_154363_16 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000344 237.0
SHD2_k127_154363_17 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000008651 218.0
SHD2_k127_154363_18 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000001737 207.0
SHD2_k127_154363_19 - - - - 0.000000000000000004429 89.0
SHD2_k127_154363_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.932e-201 635.0
SHD2_k127_154363_20 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0000000001227 65.0
SHD2_k127_154363_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 610.0
SHD2_k127_154363_4 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 601.0
SHD2_k127_154363_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 539.0
SHD2_k127_154363_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 483.0
SHD2_k127_154363_7 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 485.0
SHD2_k127_154363_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 464.0
SHD2_k127_154363_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 440.0
SHD2_k127_1558692_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 553.0
SHD2_k127_1558692_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003023 245.0
SHD2_k127_1558692_2 PFAM CBS domain K04767 - - 0.0000000000000000000007182 104.0
SHD2_k127_1558692_3 GDSL-like Lipase/Acylhydrolase family - - - 0.00001431 55.0
SHD2_k127_1562857_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 1.341e-287 908.0
SHD2_k127_1562857_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 340.0
SHD2_k127_1562857_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000001469 220.0
SHD2_k127_1562857_3 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000007667 204.0
SHD2_k127_1562857_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000004168 209.0
SHD2_k127_172398_0 PFAM Radical SAM K22226 - - 9.039e-209 653.0
SHD2_k127_172398_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 1.272e-207 657.0
SHD2_k127_172398_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 511.0
SHD2_k127_172398_3 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 487.0
SHD2_k127_172398_4 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000001082 183.0
SHD2_k127_172398_5 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000001251 136.0
SHD2_k127_1748461_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 547.0
SHD2_k127_1748461_1 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 302.0
SHD2_k127_1748461_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002781 282.0
SHD2_k127_1748461_3 branched-chain amino acid transmembrane transporter activity K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
SHD2_k127_1748461_4 ABC transporter, ATP-binding protein K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
SHD2_k127_1748461_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000002465 49.0
SHD2_k127_1861383_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 3.818e-229 720.0
SHD2_k127_1861383_1 Major Facilitator Superfamily K08177 - - 1.096e-209 657.0
SHD2_k127_1861383_10 PFAM CBS domain K04767 - - 0.00000000000000000000000000000000000000009182 158.0
SHD2_k127_1861383_11 Phage integrase family - - - 0.000000001809 63.0
SHD2_k127_1861383_12 transporter antisigma-factor antagonist STAS - - - 0.0000001668 57.0
SHD2_k127_1861383_13 PFAM Anti-sigma-28 factor FlgM K02398 - - 0.0002075 48.0
SHD2_k127_1861383_2 Sugar (and other) transporter K03446 - - 1.808e-201 640.0
SHD2_k127_1861383_3 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 460.0
SHD2_k127_1861383_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 434.0
SHD2_k127_1861383_5 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 345.0
SHD2_k127_1861383_6 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 301.0
SHD2_k127_1861383_7 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 266.0
SHD2_k127_1861383_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
SHD2_k127_1861383_9 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000002949 207.0
SHD2_k127_1914925_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 584.0
SHD2_k127_1914925_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 569.0
SHD2_k127_1914925_2 PFAM cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 536.0
SHD2_k127_1914925_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 412.0
SHD2_k127_1914925_4 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 405.0
SHD2_k127_1914925_5 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000001322 205.0
SHD2_k127_1914925_6 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000009695 100.0
SHD2_k127_1914925_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000001358 90.0
SHD2_k127_1914925_8 Belongs to the HesB IscA family - - - 0.00000000000000002085 83.0
SHD2_k127_1914925_9 PFAM Cyclic nucleotide-binding domain - - - 0.00000000005572 69.0
SHD2_k127_1947141_0 Protein export membrane protein K03296,K18138 - - 5.612e-228 709.0
SHD2_k127_1947141_1 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 571.0
SHD2_k127_1947141_2 Patatin phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 415.0
SHD2_k127_1949_0 carbon starvation protein CstA K06200 - - 3.666e-321 992.0
SHD2_k127_1949_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.129e-217 689.0
SHD2_k127_1949_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001394 209.0
SHD2_k127_1949_11 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 0.0000000000000000000000000000000000000000000000000000000002275 221.0
SHD2_k127_1949_12 4Fe-4S dicluster domain K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000001694 145.0
SHD2_k127_1949_13 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000002478 142.0
SHD2_k127_1949_14 - - - - 0.00000000000000000000000000000000006546 145.0
SHD2_k127_1949_15 Phage integrase family - - - 0.000000000000000000000001101 108.0
SHD2_k127_1949_16 - - - - 0.00000000000002418 80.0
SHD2_k127_1949_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 558.0
SHD2_k127_1949_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 540.0
SHD2_k127_1949_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 514.0
SHD2_k127_1949_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 453.0
SHD2_k127_1949_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 284.0
SHD2_k127_1949_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004661 253.0
SHD2_k127_1949_8 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007058 262.0
SHD2_k127_1949_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001219 237.0
SHD2_k127_198657_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 553.0
SHD2_k127_198657_1 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 534.0
SHD2_k127_198657_10 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000009382 152.0
SHD2_k127_198657_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001359 138.0
SHD2_k127_198657_12 - - - - 0.00000000000000000000000000000000785 134.0
SHD2_k127_198657_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000003593 129.0
SHD2_k127_198657_14 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.0000000000000000001077 93.0
SHD2_k127_198657_15 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000002221 94.0
SHD2_k127_198657_16 - - - - 0.00000000000000000035 90.0
SHD2_k127_198657_17 Rubrerythrin - - - 0.0000000000000000008273 94.0
SHD2_k127_198657_18 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000148 85.0
SHD2_k127_198657_19 phosphoesterases, related to the Icc protein - - - 0.0000001239 64.0
SHD2_k127_198657_2 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 342.0
SHD2_k127_198657_20 - - - - 0.00001138 54.0
SHD2_k127_198657_21 - - - - 0.00005963 48.0
SHD2_k127_198657_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 303.0
SHD2_k127_198657_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 308.0
SHD2_k127_198657_5 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 299.0
SHD2_k127_198657_6 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000001087 231.0
SHD2_k127_198657_7 Papain-like cysteine protease AvrRpt2 - - - 0.000000000000000000000000000000000000000000000002721 177.0
SHD2_k127_198657_8 domain, Protein K15125 - - 0.00000000000000000000000000000000000000000000003848 181.0
SHD2_k127_198657_9 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000001686 148.0
SHD2_k127_2002585_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 2.923e-226 715.0
SHD2_k127_2002585_1 HMGL-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 428.0
SHD2_k127_2002585_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 389.0
SHD2_k127_2043081_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 524.0
SHD2_k127_2043081_1 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 375.0
SHD2_k127_2043081_2 Putative heavy-metal chelation K09138 - - 0.00000000000000000000000000000000000000000000001919 179.0
SHD2_k127_2043081_3 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000002439 139.0
SHD2_k127_2043081_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000001643 118.0
SHD2_k127_2043081_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000004434 59.0
SHD2_k127_2155128_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 4.711e-227 723.0
SHD2_k127_2155128_1 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 415.0
SHD2_k127_2184199_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.794e-266 834.0
SHD2_k127_2184199_1 Elongation factor Tu domain 2 K02355 - - 3.486e-264 830.0
SHD2_k127_2184199_10 Conserved carboxylase domain K01958 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000005085 231.0
SHD2_k127_2184199_11 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000001756 210.0
SHD2_k127_2184199_12 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000001379 197.0
SHD2_k127_2184199_13 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001669 158.0
SHD2_k127_2184199_14 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000000000008635 126.0
SHD2_k127_2184199_15 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000002026 123.0
SHD2_k127_2184199_16 - - - - 0.0000000000000000000000001733 108.0
SHD2_k127_2184199_2 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 3.617e-250 778.0
SHD2_k127_2184199_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 398.0
SHD2_k127_2184199_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 326.0
SHD2_k127_2184199_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 307.0
SHD2_k127_2184199_6 2-keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001902 281.0
SHD2_k127_2184199_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 274.0
SHD2_k127_2184199_8 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001054 256.0
SHD2_k127_2184199_9 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000001069 237.0
SHD2_k127_2205526_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.747e-268 829.0
SHD2_k127_2205526_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
SHD2_k127_221214_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 410.0
SHD2_k127_221214_1 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 349.0
SHD2_k127_221214_2 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 289.0
SHD2_k127_221214_3 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000003348 218.0
SHD2_k127_221214_4 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000005622 125.0
SHD2_k127_221214_5 nucleotide-binding Protein - - - 0.000000000001678 72.0
SHD2_k127_221214_6 - - - - 0.00000008574 59.0
SHD2_k127_2223751_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 2.606e-225 705.0
SHD2_k127_2223751_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.821e-217 691.0
SHD2_k127_2223751_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000004046 262.0
SHD2_k127_2223751_11 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
SHD2_k127_2223751_12 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000000000000000006972 226.0
SHD2_k127_2223751_13 DGC domain - - - 0.000000000000000000000000000000000000000000000000000003317 195.0
SHD2_k127_2223751_14 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000001414 178.0
SHD2_k127_2223751_15 Cache_2 - - - 0.00000000000000000000000000000000000000000001558 166.0
SHD2_k127_2223751_16 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673,K03981 - 5.3.4.1 0.0000000000000000000000000000000000326 145.0
SHD2_k127_2223751_17 Heavy-metal resistance - - - 0.00000000000000000000000000000000006308 142.0
SHD2_k127_2223751_18 NifU-like N terminal domain K04488 - - 0.0000000000000000000000003887 110.0
SHD2_k127_2223751_19 toxin-antitoxin pair type II binding - - - 0.000000000000000000000001883 104.0
SHD2_k127_2223751_2 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 3.346e-201 642.0
SHD2_k127_2223751_21 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000397 75.0
SHD2_k127_2223751_22 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000001274 72.0
SHD2_k127_2223751_25 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000003373 51.0
SHD2_k127_2223751_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.917e-200 646.0
SHD2_k127_2223751_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 554.0
SHD2_k127_2223751_5 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 516.0
SHD2_k127_2223751_6 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 459.0
SHD2_k127_2223751_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 340.0
SHD2_k127_2223751_8 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 332.0
SHD2_k127_2223751_9 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009077 274.0
SHD2_k127_2297943_0 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 3.607e-197 621.0
SHD2_k127_2297943_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 437.0
SHD2_k127_2297943_2 transcriptional K11476 - - 0.0000000000008957 71.0
SHD2_k127_2303344_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 5.919e-291 904.0
SHD2_k127_2303344_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 7.145e-197 623.0
SHD2_k127_2303344_2 PFAM chemotaxis sensory transducer K03406 - - 9.492e-196 629.0
SHD2_k127_2303344_3 Adenylate kinase, active site lid K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 298.0
SHD2_k127_2303344_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 229.0
SHD2_k127_2303344_5 NlpC/P60 family K19223 - - 0.0000000000000000000000000000000000000000000000000000000000000007966 231.0
SHD2_k127_2303344_6 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000001379 192.0
SHD2_k127_2305494_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 6.526e-285 893.0
SHD2_k127_2305494_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 530.0
SHD2_k127_2305494_10 AIPR protein - - - 0.0000000000000666 77.0
SHD2_k127_2305494_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 493.0
SHD2_k127_2305494_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 464.0
SHD2_k127_2305494_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 423.0
SHD2_k127_2305494_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004422 284.0
SHD2_k127_2305494_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
SHD2_k127_2305494_8 transposition K07483,K07497 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000001816 104.0
SHD2_k127_2305494_9 Putative regulatory protein - - - 0.00000000000000000000001827 102.0
SHD2_k127_23240_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1395.0
SHD2_k127_23240_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0 1109.0
SHD2_k127_23240_10 NiFe/NiFeSe hydrogenase small subunit C-terminal K05927,K18008 - 1.12.2.1,1.12.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 439.0
SHD2_k127_23240_11 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 379.0
SHD2_k127_23240_12 PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 385.0
SHD2_k127_23240_13 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 354.0
SHD2_k127_23240_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 357.0
SHD2_k127_23240_15 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 336.0
SHD2_k127_23240_16 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 321.0
SHD2_k127_23240_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 322.0
SHD2_k127_23240_18 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 309.0
SHD2_k127_23240_19 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
SHD2_k127_23240_2 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0 1103.0
SHD2_k127_23240_20 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 299.0
SHD2_k127_23240_21 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 296.0
SHD2_k127_23240_22 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 285.0
SHD2_k127_23240_23 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
SHD2_k127_23240_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001963 282.0
SHD2_k127_23240_25 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000373 284.0
SHD2_k127_23240_26 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003295 273.0
SHD2_k127_23240_27 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000002016 232.0
SHD2_k127_23240_28 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000198 215.0
SHD2_k127_23240_29 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001392 207.0
SHD2_k127_23240_3 Nickel-dependent hydrogenase K06281 - 1.12.99.6 1.238e-227 717.0
SHD2_k127_23240_30 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000001214 203.0
SHD2_k127_23240_31 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000000002576 201.0
SHD2_k127_23240_32 Ribbon-helix-helix protein, copG family K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000008576 201.0
SHD2_k127_23240_33 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000001393 203.0
SHD2_k127_23240_34 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000002563 169.0
SHD2_k127_23240_35 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000006331 165.0
SHD2_k127_23240_36 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000372 146.0
SHD2_k127_23240_37 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000004152 145.0
SHD2_k127_23240_38 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000007346 113.0
SHD2_k127_23240_39 hydrogenase assembly chaperone HypC K04653 - - 0.000000000000000003317 86.0
SHD2_k127_23240_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 9.899e-215 678.0
SHD2_k127_23240_40 BON domain - - - 0.0000000000000001748 80.0
SHD2_k127_23240_41 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000002 76.0
SHD2_k127_23240_42 - - - - 0.0002677 46.0
SHD2_k127_23240_5 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 576.0
SHD2_k127_23240_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 569.0
SHD2_k127_23240_7 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 558.0
SHD2_k127_23240_8 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 524.0
SHD2_k127_23240_9 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 497.0
SHD2_k127_2335157_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 551.0
SHD2_k127_2335157_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000162 75.0
SHD2_k127_2335157_2 Transcriptional - - - 0.0000872 50.0
SHD2_k127_2336754_0 Responsible for energy coupling to the transport system K16784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 329.0
SHD2_k127_2336754_1 HRDC domain K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 301.0
SHD2_k127_2336754_2 Cobalt transport protein K16783,K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001498 256.0
SHD2_k127_2336754_3 PFAM BioY family K03523 - - 0.0000000000000000000000000000000000000000000000000000000004922 209.0
SHD2_k127_2336754_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0002699 44.0
SHD2_k127_237186_0 response regulator receiver K02481,K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 526.0
SHD2_k127_237186_1 electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 445.0
SHD2_k127_237186_10 phosphorelay signal transduction system - - - 0.00000000000000000000000004994 111.0
SHD2_k127_237186_11 - - - - 0.0000000000000000000000001346 111.0
SHD2_k127_237186_12 Protein of unknown function (DUF3313) - - - 0.0000000000000000000002663 101.0
SHD2_k127_237186_13 amino acid activation for nonribosomal peptide biosynthetic process K02406,K19693 - - 0.000000000000001474 80.0
SHD2_k127_237186_14 - - - - 0.000000000000002318 80.0
SHD2_k127_237186_16 ACT domain protein - - - 0.00000002049 61.0
SHD2_k127_237186_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 347.0
SHD2_k127_237186_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 339.0
SHD2_k127_237186_4 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000178 290.0
SHD2_k127_237186_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
SHD2_k127_237186_6 Universal stress protein family - - - 0.000000000000000000000000000000000000000000002593 168.0
SHD2_k127_237186_7 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000004095 146.0
SHD2_k127_237186_9 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000002703 125.0
SHD2_k127_2391267_0 PFAM AMP-dependent synthetase and ligase K00666 - - 8.933e-302 930.0
SHD2_k127_2391267_1 B12 binding domain - - - 0.000000000000000000000000000000003409 140.0
SHD2_k127_2415328_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 0.0 1122.0
SHD2_k127_2415328_1 methylmalonyl-CoA decarboxylase alpha subunit - - - 8.675e-231 723.0
SHD2_k127_2415328_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009139 278.0
SHD2_k127_2415328_11 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000178 231.0
SHD2_k127_2415328_12 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000002185 216.0
SHD2_k127_2415328_13 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000000000000000000000002268 202.0
SHD2_k127_2415328_14 ISXO2-like transposase domain K07488 - - 0.00000000000000000000000000000000004731 143.0
SHD2_k127_2415328_15 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000006972 121.0
SHD2_k127_2415328_16 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000001286 86.0
SHD2_k127_2415328_17 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000007041 80.0
SHD2_k127_2415328_19 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000005694 61.0
SHD2_k127_2415328_2 succinate CoA transferase K18118 - 2.8.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 611.0
SHD2_k127_2415328_20 - - - - 0.000000003717 58.0
SHD2_k127_2415328_3 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 525.0
SHD2_k127_2415328_4 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 449.0
SHD2_k127_2415328_5 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 418.0
SHD2_k127_2415328_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 365.0
SHD2_k127_2415328_7 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 314.0
SHD2_k127_2415328_8 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
SHD2_k127_2415328_9 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 310.0
SHD2_k127_24288_0 Pfam:KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 592.0
SHD2_k127_24288_1 Baseplate assembly protein - - - 0.0000000000000000000000000000000008238 132.0
SHD2_k127_24288_2 - - - - 0.0000000000000006218 78.0
SHD2_k127_24288_3 CsbD-like - - - 0.00000000003453 64.0
SHD2_k127_2429847_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 379.0
SHD2_k127_2429847_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000134 223.0
SHD2_k127_2429847_2 regulation of response to stimulus K02014,K13730 - - 0.000000000000000000005478 108.0
SHD2_k127_2429847_3 - - - - 0.0000000001549 65.0
SHD2_k127_2432352_0 Silent information regulator protein Sir2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 367.0
SHD2_k127_2432352_1 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 361.0
SHD2_k127_2432352_2 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
SHD2_k127_2432352_3 Fumarate K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 265.0
SHD2_k127_2432352_4 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
SHD2_k127_2432352_5 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000005936 202.0
SHD2_k127_2432352_6 Dicarboxylate carrier - - - 0.000000000000000000000000000000000000000000000000004795 182.0
SHD2_k127_2432352_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000455 108.0
SHD2_k127_2432352_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000001906 105.0
SHD2_k127_2455195_0 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 1.406e-256 807.0
SHD2_k127_2455195_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.416e-224 709.0
SHD2_k127_2455195_2 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 401.0
SHD2_k127_2455195_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 319.0
SHD2_k127_2455195_4 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000001176 139.0
SHD2_k127_2455195_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000008112 78.0
SHD2_k127_2477174_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.704e-236 733.0
SHD2_k127_2477174_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.527e-208 680.0
SHD2_k127_2477174_10 Domain of unknown function (DUF1850) - - - 0.00000000000000000009274 96.0
SHD2_k127_2477174_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 544.0
SHD2_k127_2477174_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 513.0
SHD2_k127_2477174_4 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 392.0
SHD2_k127_2477174_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 381.0
SHD2_k127_2477174_6 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 327.0
SHD2_k127_2477174_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
SHD2_k127_2477174_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000008043 209.0
SHD2_k127_2477174_9 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000001554 119.0
SHD2_k127_2482505_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 551.0
SHD2_k127_2482505_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 436.0
SHD2_k127_2482505_2 helix_turn_helix, Lux Regulon - - - 0.000000001425 63.0
SHD2_k127_2506493_0 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
SHD2_k127_2506493_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000003609 211.0
SHD2_k127_2506493_2 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000006691 191.0
SHD2_k127_2550968_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 3.341e-203 638.0
SHD2_k127_2550968_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 578.0
SHD2_k127_2550968_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000002284 106.0
SHD2_k127_2550968_11 - - - - 0.000000000000002668 87.0
SHD2_k127_2550968_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 495.0
SHD2_k127_2550968_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 465.0
SHD2_k127_2550968_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 376.0
SHD2_k127_2550968_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
SHD2_k127_2550968_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003673 272.0
SHD2_k127_2550968_7 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001766 262.0
SHD2_k127_2550968_8 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001975 237.0
SHD2_k127_2550968_9 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000004547 180.0
SHD2_k127_259293_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 6.328e-199 631.0
SHD2_k127_259293_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 435.0
SHD2_k127_259293_2 CGGC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001992 267.0
SHD2_k127_259293_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000002216 229.0
SHD2_k127_259293_4 Belongs to the UPF0251 family - - - 0.000000000000000000000000000000000000005496 151.0
SHD2_k127_259293_5 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000005979 147.0
SHD2_k127_259293_6 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000001085 139.0
SHD2_k127_259293_7 lactate metabolic process K00113,K21834 - 1.1.5.3 0.0000000000000000000002184 100.0
SHD2_k127_259293_8 cyclic nucleotide binding K10914,K12132,K21564 - 2.7.11.1 0.0000000000001041 78.0
SHD2_k127_2610988_0 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 9.681e-271 843.0
SHD2_k127_2610988_1 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003497 269.0
SHD2_k127_2610988_2 helix_turn_helix, Lux Regulon K14979 - - 0.00000000000000000000000000000000000000000000000000000000000000000005138 243.0
SHD2_k127_2610988_3 PAC sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000005549 192.0
SHD2_k127_2610988_4 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000001699 170.0
SHD2_k127_2618860_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.839e-318 986.0
SHD2_k127_2618860_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 4.968e-282 877.0
SHD2_k127_2618860_10 ABC transporter, permease protein K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 518.0
SHD2_k127_2618860_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 469.0
SHD2_k127_2618860_12 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 469.0
SHD2_k127_2618860_13 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 438.0
SHD2_k127_2618860_14 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 426.0
SHD2_k127_2618860_15 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 402.0
SHD2_k127_2618860_16 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 394.0
SHD2_k127_2618860_17 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 351.0
SHD2_k127_2618860_18 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 321.0
SHD2_k127_2618860_19 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000206 265.0
SHD2_k127_2618860_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 3.829e-230 721.0
SHD2_k127_2618860_20 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009613 266.0
SHD2_k127_2618860_21 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000939 242.0
SHD2_k127_2618860_22 COGs COG1144 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase delta subunit K00171,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000007144 208.0
SHD2_k127_2618860_23 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000000000000000706 158.0
SHD2_k127_2618860_24 Dehydrogenase K00096 - 1.1.1.261 0.000000000000000000000000000001159 138.0
SHD2_k127_2618860_25 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000009256 100.0
SHD2_k127_2618860_26 4Fe-4S dicluster domain - - - 0.000000000000000000002687 105.0
SHD2_k127_2618860_27 Psort location Cytoplasmic, score - - - 0.0000000003245 65.0
SHD2_k127_2618860_28 VIT family - - - 0.0000233 56.0
SHD2_k127_2618860_3 AAA family ATPase, CDC48 subfamily - - - 1.892e-227 725.0
SHD2_k127_2618860_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 3.087e-218 694.0
SHD2_k127_2618860_5 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 1.172e-214 679.0
SHD2_k127_2618860_6 PFAM response regulator receiver K11384 - - 1.422e-200 632.0
SHD2_k127_2618860_7 Pyruvate carboxyltransferase K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 603.0
SHD2_k127_2618860_8 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 572.0
SHD2_k127_2618860_9 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 553.0
SHD2_k127_2661660_0 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 307.0
SHD2_k127_2661660_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008784 228.0
SHD2_k127_2661660_2 - - - - 0.000000000000000000000000000000000000000000000000000000001219 210.0
SHD2_k127_2661660_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000001943 178.0
SHD2_k127_2661660_4 - - - - 0.00000000000000000000000002998 113.0
SHD2_k127_2661660_5 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000003022 81.0
SHD2_k127_2661660_6 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000009448 85.0
SHD2_k127_2661660_7 ThiF family K03148 - 2.7.7.73 0.0000000000000174 84.0
SHD2_k127_2661660_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000006156 70.0
SHD2_k127_2759287_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 537.0
SHD2_k127_2759287_1 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000286 257.0
SHD2_k127_2759287_2 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000002515 219.0
SHD2_k127_2759287_3 - - - - 0.00005363 51.0
SHD2_k127_276115_0 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 505.0
SHD2_k127_276115_1 Protein of unknown function (DUF3443) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 420.0
SHD2_k127_276115_10 Nitroreductase - - - 0.000000000000000000000000000000000000000000000002735 181.0
SHD2_k127_276115_11 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000004324 179.0
SHD2_k127_276115_12 Protein of unknown function (DUF2844) - - - 0.00000000000000000000000000000000000000000005273 166.0
SHD2_k127_276115_13 - - - - 0.00000000000000007764 87.0
SHD2_k127_276115_14 - - - - 0.0000000000000001829 83.0
SHD2_k127_276115_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000221 74.0
SHD2_k127_276115_16 - - - - 0.00000000002432 68.0
SHD2_k127_276115_17 Tetratricopeptide repeat - - - 0.0000000002701 72.0
SHD2_k127_276115_19 PFAM DivIVA family protein K04074 - - 0.000638 51.0
SHD2_k127_276115_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 413.0
SHD2_k127_276115_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 399.0
SHD2_k127_276115_4 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
SHD2_k127_276115_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 364.0
SHD2_k127_276115_6 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 348.0
SHD2_k127_276115_7 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 310.0
SHD2_k127_276115_8 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005358 288.0
SHD2_k127_276115_9 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000001772 256.0
SHD2_k127_2784748_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2261.0
SHD2_k127_2784748_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2061.0
SHD2_k127_2784748_10 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 351.0
SHD2_k127_2784748_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 325.0
SHD2_k127_2784748_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 289.0
SHD2_k127_2784748_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001096 280.0
SHD2_k127_2784748_14 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001908 281.0
SHD2_k127_2784748_15 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000008152 239.0
SHD2_k127_2784748_16 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000001332 223.0
SHD2_k127_2784748_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004192 226.0
SHD2_k127_2784748_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000009974 214.0
SHD2_k127_2784748_19 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003409 213.0
SHD2_k127_2784748_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.04e-303 944.0
SHD2_k127_2784748_20 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000009767 205.0
SHD2_k127_2784748_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000297 205.0
SHD2_k127_2784748_22 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002472 205.0
SHD2_k127_2784748_23 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000004865 187.0
SHD2_k127_2784748_24 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001301 188.0
SHD2_k127_2784748_25 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000102 184.0
SHD2_k127_2784748_26 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000003294 175.0
SHD2_k127_2784748_27 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000001773 159.0
SHD2_k127_2784748_28 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002038 166.0
SHD2_k127_2784748_29 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000239 162.0
SHD2_k127_2784748_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.22e-241 750.0
SHD2_k127_2784748_30 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000131 155.0
SHD2_k127_2784748_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000001367 141.0
SHD2_k127_2784748_32 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000001788 139.0
SHD2_k127_2784748_33 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002834 139.0
SHD2_k127_2784748_34 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002254 124.0
SHD2_k127_2784748_35 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002476 117.0
SHD2_k127_2784748_36 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003498 111.0
SHD2_k127_2784748_37 peptidase U32 - - - 0.0000000000000000006834 89.0
SHD2_k127_2784748_38 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000002777 80.0
SHD2_k127_2784748_39 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000003782 75.0
SHD2_k127_2784748_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.243e-225 702.0
SHD2_k127_2784748_40 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000007276 64.0
SHD2_k127_2784748_5 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.024e-211 683.0
SHD2_k127_2784748_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 462.0
SHD2_k127_2784748_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 436.0
SHD2_k127_2784748_8 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 353.0
SHD2_k127_2784748_9 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 342.0
SHD2_k127_2805020_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 365.0
SHD2_k127_2805020_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 303.0
SHD2_k127_2805020_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000002233 67.0
SHD2_k127_2805498_0 PFAM Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 0.0 1301.0
SHD2_k127_2805498_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 511.0
SHD2_k127_2805498_10 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
SHD2_k127_2805498_11 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.00000000000000000000000000000000000000009683 162.0
SHD2_k127_2805498_12 PilZ domain - - - 0.000000000000000000000000000000000000313 147.0
SHD2_k127_2805498_13 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000797 122.0
SHD2_k127_2805498_14 Member of the two-component regulatory system MprB MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000006053 81.0
SHD2_k127_2805498_15 Protein of unknown function (DUF3568) - - - 0.00000000000001987 85.0
SHD2_k127_2805498_2 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 450.0
SHD2_k127_2805498_3 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 441.0
SHD2_k127_2805498_4 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 396.0
SHD2_k127_2805498_5 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 368.0
SHD2_k127_2805498_6 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 336.0
SHD2_k127_2805498_7 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 286.0
SHD2_k127_2805498_8 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002622 278.0
SHD2_k127_2805498_9 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000593 239.0
SHD2_k127_2886261_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 569.0
SHD2_k127_2886261_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 315.0
SHD2_k127_2886261_10 - - - - 0.00008238 49.0
SHD2_k127_2886261_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003671 244.0
SHD2_k127_2886261_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000002136 175.0
SHD2_k127_2886261_4 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000006705 167.0
SHD2_k127_2886261_5 Transposase zinc-ribbon domain K07488 - - 0.00000000000000000000000000000000001434 139.0
SHD2_k127_2886261_6 B-1 B cell differentiation - - - 0.000000000000000000000007742 116.0
SHD2_k127_2886261_7 - - - - 0.00000000132 66.0
SHD2_k127_2886261_8 - - - - 0.000000005952 66.0
SHD2_k127_2886261_9 Domain of unknown function (DUF4384) - - - 0.0000006026 61.0
SHD2_k127_2907446_0 Domain of unknown function (DUF1998) K06877 - - 3.463e-272 858.0
SHD2_k127_2907446_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 374.0
SHD2_k127_2907446_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 327.0
SHD2_k127_2907446_3 PFAM Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
SHD2_k127_2907446_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001139 247.0
SHD2_k127_2907446_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000005759 179.0
SHD2_k127_2907446_6 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000004276 141.0
SHD2_k127_2907446_7 Rubredoxin - - - 0.000000000000000000000002914 102.0
SHD2_k127_2956066_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 337.0
SHD2_k127_2956066_1 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 316.0
SHD2_k127_2956066_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 282.0
SHD2_k127_2956066_3 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007805 280.0
SHD2_k127_2956066_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007645 274.0
SHD2_k127_2956066_5 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000104 261.0
SHD2_k127_2956066_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000002046 229.0
SHD2_k127_2956066_7 Oxidoreductase family, C-terminal alpha/beta domain K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000002482 175.0
SHD2_k127_2988075_0 Peptidase M16C associated K06972 - - 0.0 1151.0
SHD2_k127_2988075_1 PFAM ferredoxin-dependent glutamate synthase - - - 8.334e-276 855.0
SHD2_k127_2988075_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 336.0
SHD2_k127_2988075_3 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000002644 223.0
SHD2_k127_2988075_5 Uracil-DNA glycosylase - - - 0.00000000000003378 76.0
SHD2_k127_2988075_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000001141 65.0
SHD2_k127_3007439_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 2.602e-196 627.0
SHD2_k127_3007439_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
SHD2_k127_3007439_10 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.00000000000000000000000005606 109.0
SHD2_k127_3007439_11 PfkB domain protein - - - 0.000000000000000002149 96.0
SHD2_k127_3007439_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 380.0
SHD2_k127_3007439_3 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 373.0
SHD2_k127_3007439_4 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 348.0
SHD2_k127_3007439_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 303.0
SHD2_k127_3007439_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 297.0
SHD2_k127_3007439_7 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000004014 237.0
SHD2_k127_3007439_8 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000103 145.0
SHD2_k127_3007439_9 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000009292 126.0
SHD2_k127_3095125_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 3.031e-274 849.0
SHD2_k127_3095125_1 Psort location CytoplasmicMembrane, score - - - 5.132e-270 834.0
SHD2_k127_3095125_10 SNARE associated Golgi protein - - - 0.0000000000000000000000000001178 125.0
SHD2_k127_3095125_11 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000003164 98.0
SHD2_k127_3095125_12 rRNA binding - - - 0.00000000000000000003218 94.0
SHD2_k127_3095125_13 NifU domain-containing protein - - - 0.000000000000000002097 89.0
SHD2_k127_3095125_14 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.0000000000000005061 87.0
SHD2_k127_3095125_15 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000006966 80.0
SHD2_k127_3095125_16 - - - - 0.000000000002846 72.0
SHD2_k127_3095125_2 acetyl-CoA hydrolase K18122 - - 8.415e-206 647.0
SHD2_k127_3095125_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 605.0
SHD2_k127_3095125_4 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 370.0
SHD2_k127_3095125_5 Flavodoxin-like fold K03923,K11748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 329.0
SHD2_k127_3095125_6 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000769 267.0
SHD2_k127_3095125_7 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001765 212.0
SHD2_k127_3095125_8 - - - - 0.00000000000000000000000000000002356 135.0
SHD2_k127_3095125_9 - - - - 0.0000000000000000000000000000001085 132.0
SHD2_k127_316622_0 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 509.0
SHD2_k127_316622_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003844 299.0
SHD2_k127_316622_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000202 185.0
SHD2_k127_316622_3 Pfam:N_methyl_2 - - - 0.0000000000000000000003236 105.0
SHD2_k127_316622_4 Pilus assembly protein PilX K02673 - - 0.0000001874 63.0
SHD2_k127_3243395_0 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 1.805e-200 631.0
SHD2_k127_3243395_1 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 354.0
SHD2_k127_3243395_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003899 250.0
SHD2_k127_3264071_0 Thiamine-phosphate synthase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 428.0
SHD2_k127_3264071_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001794 237.0
SHD2_k127_3279418_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 465.0
SHD2_k127_3279418_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 423.0
SHD2_k127_3279418_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 403.0
SHD2_k127_3279418_3 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 364.0
SHD2_k127_3279418_4 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000001234 207.0
SHD2_k127_3279418_5 HAD-superfamily hydrolase, subfamily IB K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000001849 204.0
SHD2_k127_3279418_6 GtrA-like protein - - - 0.0000000000000000000000000000000000000007796 162.0
SHD2_k127_3279537_0 Protein export membrane protein K03296,K18138 - - 0.0 1234.0
SHD2_k127_3279537_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.681e-234 735.0
SHD2_k127_3279537_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000001058 206.0
SHD2_k127_3279537_11 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000001322 207.0
SHD2_k127_3279537_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000001109 172.0
SHD2_k127_3279537_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000002352 144.0
SHD2_k127_3279537_16 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000000000007294 139.0
SHD2_k127_3279537_17 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000004322 129.0
SHD2_k127_3279537_18 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000000000006008 128.0
SHD2_k127_3279537_19 Ion transport 2 domain protein - - - 0.00000000000000000000000000001317 128.0
SHD2_k127_3279537_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.293e-212 670.0
SHD2_k127_3279537_21 CsbD-like - - - 0.0000000000000003211 79.0
SHD2_k127_3279537_22 transcription factor binding K12132 - 2.7.11.1 0.0000000000000005063 89.0
SHD2_k127_3279537_23 Alternative locus ID - - - 0.00000000006389 70.0
SHD2_k127_3279537_25 PFAM Response regulator receiver domain - - - 0.0000002462 52.0
SHD2_k127_3279537_26 - - - - 0.00001668 54.0
SHD2_k127_3279537_3 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 569.0
SHD2_k127_3279537_4 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 505.0
SHD2_k127_3279537_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 483.0
SHD2_k127_3279537_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 422.0
SHD2_k127_3279537_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 374.0
SHD2_k127_3279537_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 312.0
SHD2_k127_3279537_9 Gamma subunit K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 245.0
SHD2_k127_328136_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 312.0
SHD2_k127_328136_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002074 261.0
SHD2_k127_328136_2 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000001078 216.0
SHD2_k127_328136_3 Domain of unknown function (DUF697) K08990 - - 0.00000000000000000000000000000000000000000000000000001998 200.0
SHD2_k127_328136_4 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000009265 163.0
SHD2_k127_328136_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000002262 96.0
SHD2_k127_328136_6 - - - - 0.00000000000009115 76.0
SHD2_k127_3283166_0 PFAM response regulator receiver K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 346.0
SHD2_k127_3283166_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000001546 216.0
SHD2_k127_3283166_2 PFAM Extracellular solute-binding protein, family 3 - - - 0.000000000000000000000000000000000000000773 160.0
SHD2_k127_3283166_3 diguanylate cyclase - - - 0.0000000000000001365 91.0
SHD2_k127_3283166_5 Fe-S oxidoreductase - - - 0.0007427 42.0
SHD2_k127_3349450_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1477.0
SHD2_k127_3349450_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1089.0
SHD2_k127_3349450_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001766 259.0
SHD2_k127_3349450_3 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000006323 236.0
SHD2_k127_3349450_4 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000003286 171.0
SHD2_k127_3349450_5 - - - - 0.0000000000002729 74.0
SHD2_k127_3349450_6 OsmC-like protein - - - 0.0001545 47.0
SHD2_k127_3355329_0 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 341.0
SHD2_k127_3355329_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003344 263.0
SHD2_k127_3355329_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000669 206.0
SHD2_k127_3355329_3 MFS_1 like family K08161 - - 0.00000000000007287 83.0
SHD2_k127_3370544_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 592.0
SHD2_k127_3370544_1 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 543.0
SHD2_k127_3370544_10 PFAM GAF domain protein - - - 0.00000000000000000000000000000000000000000000000000001516 195.0
SHD2_k127_3370544_11 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000001329 149.0
SHD2_k127_3370544_12 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000002768 131.0
SHD2_k127_3370544_13 - - - - 0.00000001015 64.0
SHD2_k127_3370544_14 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.000003484 53.0
SHD2_k127_3370544_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 500.0
SHD2_k127_3370544_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 494.0
SHD2_k127_3370544_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 430.0
SHD2_k127_3370544_5 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 396.0
SHD2_k127_3370544_6 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 371.0
SHD2_k127_3370544_7 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 339.0
SHD2_k127_3370544_8 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 331.0
SHD2_k127_3370544_9 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001061 255.0
SHD2_k127_3397880_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 600.0
SHD2_k127_3397880_1 Prokaryotic cytochrome b561 K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 315.0
SHD2_k127_3397880_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000001121 178.0
SHD2_k127_3397880_3 spectrin binding - - - 0.00000000000000000000000000000003737 141.0
SHD2_k127_3442278_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 5.815e-246 808.0
SHD2_k127_3442278_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.003e-211 663.0
SHD2_k127_3442278_10 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000009832 216.0
SHD2_k127_3442278_11 Tripartite tricarboxylate transporter TctB family - - - 0.000009641 54.0
SHD2_k127_3442278_12 Sulfatase K01130 - 3.1.6.1 0.0002298 44.0
SHD2_k127_3442278_2 POTRA domain TamA domain 1 K07277,K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 579.0
SHD2_k127_3442278_3 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 545.0
SHD2_k127_3442278_4 Formate/nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 516.0
SHD2_k127_3442278_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 354.0
SHD2_k127_3442278_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 346.0
SHD2_k127_3442278_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000005799 255.0
SHD2_k127_3442278_8 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000002645 267.0
SHD2_k127_3442278_9 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000008378 249.0
SHD2_k127_3483623_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.089e-252 795.0
SHD2_k127_3483623_1 PFAM Radical SAM - - - 3.647e-213 676.0
SHD2_k127_3483623_10 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 466.0
SHD2_k127_3483623_11 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 482.0
SHD2_k127_3483623_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 429.0
SHD2_k127_3483623_13 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 410.0
SHD2_k127_3483623_14 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 391.0
SHD2_k127_3483623_15 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 354.0
SHD2_k127_3483623_16 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 316.0
SHD2_k127_3483623_17 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 304.0
SHD2_k127_3483623_18 YceG-like family K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004709 292.0
SHD2_k127_3483623_19 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000005947 211.0
SHD2_k127_3483623_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.793e-198 627.0
SHD2_k127_3483623_20 Essential cell division protein K03589 - - 0.00000000000000000000000000000000000000000000000000000000002934 215.0
SHD2_k127_3483623_21 Elongation factor Tu domain 2 K03833 - - 0.0000000000000000000000000000000000006662 140.0
SHD2_k127_3483623_22 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000001588 147.0
SHD2_k127_3483623_23 AIG2-like family - - - 0.00000000000000000000000000003005 128.0
SHD2_k127_3483623_24 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000001143 115.0
SHD2_k127_3483623_25 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000952 99.0
SHD2_k127_3483623_26 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.00000000000000003083 87.0
SHD2_k127_3483623_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 587.0
SHD2_k127_3483623_4 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 584.0
SHD2_k127_3483623_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 548.0
SHD2_k127_3483623_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 550.0
SHD2_k127_3483623_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 542.0
SHD2_k127_3483623_8 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 537.0
SHD2_k127_3483623_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 478.0
SHD2_k127_3552966_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1246.0
SHD2_k127_3552966_1 Conserved carboxylase domain K01958 - 6.4.1.1 8.621e-298 921.0
SHD2_k127_3552966_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 402.0
SHD2_k127_3552966_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000107 194.0
SHD2_k127_3569342_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 4.589e-243 776.0
SHD2_k127_3569342_1 Patatin-like phospholipase K07001 - - 3.735e-236 739.0
SHD2_k127_3569342_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000001091 153.0
SHD2_k127_3569342_11 Lipocalin-like domain - - - 0.000000000000000000000000000000000003378 143.0
SHD2_k127_3569342_12 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000000000005347 129.0
SHD2_k127_3569342_2 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 5.423e-203 642.0
SHD2_k127_3569342_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 475.0
SHD2_k127_3569342_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 429.0
SHD2_k127_3569342_5 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 411.0
SHD2_k127_3569342_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 344.0
SHD2_k127_3569342_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 287.0
SHD2_k127_3569342_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 278.0
SHD2_k127_3569342_9 acetoacetate decarboxylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 261.0
SHD2_k127_3574186_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 409.0
SHD2_k127_3574186_1 Radical_SAM C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 320.0
SHD2_k127_3574186_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
SHD2_k127_3574186_3 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000002011 251.0
SHD2_k127_36120_0 Coenzyme A transferase K01026 - 2.8.3.1 2.813e-262 824.0
SHD2_k127_36120_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 7.502e-194 622.0
SHD2_k127_36120_10 O-Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002183 248.0
SHD2_k127_36120_11 HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
SHD2_k127_36120_12 MaoC like domain K17865 - 4.2.1.55 0.000000000000000000000000000000000000000000000000000000000001521 211.0
SHD2_k127_36120_13 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000007709 198.0
SHD2_k127_36120_14 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000001004 187.0
SHD2_k127_36120_15 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000000000000000000000000006125 168.0
SHD2_k127_36120_16 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000000000000000000000003203 158.0
SHD2_k127_36120_17 Diguanylate cyclase - - - 0.0000000000000000000000000000000000001985 162.0
SHD2_k127_36120_18 Endoribonuclease L-PSP - - - 0.0000000000000000000000001372 110.0
SHD2_k127_36120_19 PAS domain - - - 0.0000000000000000000000006719 122.0
SHD2_k127_36120_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 602.0
SHD2_k127_36120_20 - - - - 0.000000000000000000001257 101.0
SHD2_k127_36120_21 - - - - 0.00000000000000000008285 93.0
SHD2_k127_36120_22 - - - - 0.0000000000000008414 80.0
SHD2_k127_36120_23 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000001569 66.0
SHD2_k127_36120_24 - - - - 0.0000001022 59.0
SHD2_k127_36120_25 - - - - 0.0002841 48.0
SHD2_k127_36120_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 522.0
SHD2_k127_36120_4 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 495.0
SHD2_k127_36120_5 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 422.0
SHD2_k127_36120_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 402.0
SHD2_k127_36120_7 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 392.0
SHD2_k127_36120_8 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 311.0
SHD2_k127_36120_9 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005177 286.0
SHD2_k127_3643952_0 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 556.0
SHD2_k127_3643952_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000007251 234.0
SHD2_k127_3685883_0 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 366.0
SHD2_k127_3685883_1 TIGRFAM phenazine biosynthesis protein PhzF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 351.0
SHD2_k127_3685883_2 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001898 250.0
SHD2_k127_3685883_3 cell adhesion involved in biofilm formation - - - 0.000000000000001068 83.0
SHD2_k127_3685883_4 Protein of unknown function DUF72 - - - 0.0000001793 57.0
SHD2_k127_3685883_5 Protein of unknown function DUF72 - - - 0.0002209 47.0
SHD2_k127_3719498_0 'glutamate synthase - - - 2.35e-200 638.0
SHD2_k127_3719498_1 PFAM Thiamine pyrophosphate enzyme, C-terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 388.0
SHD2_k127_3719498_2 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000001726 199.0
SHD2_k127_3719498_3 extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000009889 192.0
SHD2_k127_3719498_4 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00003657 46.0
SHD2_k127_3724827_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000001221 180.0
SHD2_k127_3724827_1 prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.000000000008457 69.0
SHD2_k127_3724827_2 Surface antigen - - - 0.0000000003175 70.0
SHD2_k127_3838463_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1386.0
SHD2_k127_3838463_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 1.27e-301 945.0
SHD2_k127_3838463_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000009414 187.0
SHD2_k127_3838463_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000002833 154.0
SHD2_k127_3838463_12 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001967 136.0
SHD2_k127_3838463_13 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000001806 127.0
SHD2_k127_3838463_14 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000004224 124.0
SHD2_k127_3838463_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000001983 100.0
SHD2_k127_3838463_16 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000001567 82.0
SHD2_k127_3838463_17 - - - - 0.000000003148 62.0
SHD2_k127_3838463_18 Cytosol aminopeptidase family, N-terminal domain - - - 0.000002674 58.0
SHD2_k127_3838463_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 9.765e-218 679.0
SHD2_k127_3838463_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 508.0
SHD2_k127_3838463_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 413.0
SHD2_k127_3838463_5 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 351.0
SHD2_k127_3838463_6 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 304.0
SHD2_k127_3838463_7 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 280.0
SHD2_k127_3838463_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
SHD2_k127_3838463_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000004269 229.0
SHD2_k127_3982099_0 nUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000207 229.0
SHD2_k127_3982099_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000001079 179.0
SHD2_k127_3982099_2 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000003774 164.0
SHD2_k127_3982099_3 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000005361 130.0
SHD2_k127_3982099_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00001221 48.0
SHD2_k127_3985195_0 COG0714 MoxR-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 415.0
SHD2_k127_3985195_1 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 329.0
SHD2_k127_3985195_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000018 220.0
SHD2_k127_3985195_3 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000002023 199.0
SHD2_k127_410394_0 symporter activity K03307 - - 1.619e-235 742.0
SHD2_k127_410394_1 Psort location CytoplasmicMembrane, score K07793 - - 1.527e-211 667.0
SHD2_k127_410394_10 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 285.0
SHD2_k127_410394_11 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
SHD2_k127_410394_12 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009512 249.0
SHD2_k127_410394_13 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000001193 229.0
SHD2_k127_410394_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000003716 192.0
SHD2_k127_410394_15 Nitroreductase family - - - 0.0000000000000000000000000000000000002529 152.0
SHD2_k127_410394_16 FCD - - - 0.0000000000000000000000000000000005589 142.0
SHD2_k127_410394_17 Protein of unknown function (DUF2845) - - - 0.000001477 56.0
SHD2_k127_410394_18 Membrane K07794 - - 0.0006926 49.0
SHD2_k127_410394_19 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0009325 46.0
SHD2_k127_410394_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 494.0
SHD2_k127_410394_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 434.0
SHD2_k127_410394_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 425.0
SHD2_k127_410394_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 419.0
SHD2_k127_410394_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 415.0
SHD2_k127_410394_7 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 367.0
SHD2_k127_410394_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 340.0
SHD2_k127_410394_9 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 313.0
SHD2_k127_4118270_0 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 346.0
SHD2_k127_4118270_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 298.0
SHD2_k127_4118270_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 289.0
SHD2_k127_4118270_3 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005523 279.0
SHD2_k127_4118270_4 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000002236 213.0
SHD2_k127_4118270_6 DNA integration - - - 0.000002807 51.0
SHD2_k127_4136709_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 524.0
SHD2_k127_4136709_1 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
SHD2_k127_4136709_2 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000008321 238.0
SHD2_k127_4136709_3 PFAM NIL domain - - - 0.0000000000000000000000000000000000000000000000000000000000001772 216.0
SHD2_k127_4136709_4 - K07020,K18614 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.29 0.0000000000000000000000000000000000000000000000000000000002085 207.0
SHD2_k127_4136709_5 Protein of unknown function (DUF721) - - - 0.000000000002635 73.0
SHD2_k127_4151540_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1519.0
SHD2_k127_4151540_1 4Fe-4S dicluster domain - - - 3.718e-286 887.0
SHD2_k127_4151540_10 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 551.0
SHD2_k127_4151540_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 552.0
SHD2_k127_4151540_12 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 546.0
SHD2_k127_4151540_13 PFAM Uncharacterised protein family UPF0324 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 432.0
SHD2_k127_4151540_14 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 412.0
SHD2_k127_4151540_15 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 391.0
SHD2_k127_4151540_16 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 387.0
SHD2_k127_4151540_17 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 383.0
SHD2_k127_4151540_18 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 361.0
SHD2_k127_4151540_19 4Fe-4S dicluster domain K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 351.0
SHD2_k127_4151540_2 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 5.493e-284 884.0
SHD2_k127_4151540_20 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 329.0
SHD2_k127_4151540_21 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 317.0
SHD2_k127_4151540_22 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
SHD2_k127_4151540_23 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 286.0
SHD2_k127_4151540_24 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001461 292.0
SHD2_k127_4151540_25 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007734 284.0
SHD2_k127_4151540_26 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001186 273.0
SHD2_k127_4151540_27 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000884 282.0
SHD2_k127_4151540_28 phosphorelay sensor kinase activity K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001487 252.0
SHD2_k127_4151540_29 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000004489 243.0
SHD2_k127_4151540_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.097e-234 734.0
SHD2_k127_4151540_30 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000005677 231.0
SHD2_k127_4151540_31 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000005046 220.0
SHD2_k127_4151540_32 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001133 235.0
SHD2_k127_4151540_33 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000725 192.0
SHD2_k127_4151540_34 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000002701 187.0
SHD2_k127_4151540_35 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000531 183.0
SHD2_k127_4151540_36 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000008676 167.0
SHD2_k127_4151540_37 - - - - 0.000000000000000000000000000000000000000000006188 166.0
SHD2_k127_4151540_38 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000000002507 146.0
SHD2_k127_4151540_39 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000008143 138.0
SHD2_k127_4151540_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 599.0
SHD2_k127_4151540_40 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000004847 125.0
SHD2_k127_4151540_41 PFAM ATP synthase I chain - - - 0.000000000000000000000002399 106.0
SHD2_k127_4151540_43 PFAM Dissimilatory sulfite reductase D - - - 0.00000002263 57.0
SHD2_k127_4151540_44 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000008686 56.0
SHD2_k127_4151540_5 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 578.0
SHD2_k127_4151540_6 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 574.0
SHD2_k127_4151540_7 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 577.0
SHD2_k127_4151540_8 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 555.0
SHD2_k127_4151540_9 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 567.0
SHD2_k127_4165068_0 FAD binding domain K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 598.0
SHD2_k127_4165068_1 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
SHD2_k127_4165068_2 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000001161 159.0
SHD2_k127_4165068_3 FAD binding domain K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.000001283 53.0
SHD2_k127_4174334_0 DNA polymerase III, delta' K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 433.0
SHD2_k127_4174334_1 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 381.0
SHD2_k127_4174334_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000014 96.0
SHD2_k127_4174334_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 364.0
SHD2_k127_4174334_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 330.0
SHD2_k127_4174334_4 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000001779 237.0
SHD2_k127_4174334_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000001337 171.0
SHD2_k127_4174334_6 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000002218 128.0
SHD2_k127_4174334_7 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000196 110.0
SHD2_k127_4174334_8 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000005511 99.0
SHD2_k127_4174334_9 Pilus assembly protein, PilP K02664,K02665 - - 0.0000000000000000002341 95.0
SHD2_k127_4222686_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.346e-201 635.0
SHD2_k127_4222686_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 520.0
SHD2_k127_4222686_2 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 450.0
SHD2_k127_4222686_3 Protein of unknown function (DUF2905) - - - 0.0000000000000000000002259 98.0
SHD2_k127_4228798_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 5.422e-196 620.0
SHD2_k127_4228798_1 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000003875 126.0
SHD2_k127_4228798_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000001917 56.0
SHD2_k127_4261087_0 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 331.0
SHD2_k127_4261087_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000001017 166.0
SHD2_k127_4261087_2 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000002152 75.0
SHD2_k127_4286414_0 Acyl transferase domain - - - 0.0 1261.0
SHD2_k127_4286414_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 516.0
SHD2_k127_4286414_10 - - - - 0.00000000000000000001614 94.0
SHD2_k127_4286414_11 dienelactone hydrolase - - - 0.0000000000000000002311 92.0
SHD2_k127_4286414_12 Protein of unknown function (DUF3309) - - - 0.0000000000000000005381 87.0
SHD2_k127_4286414_2 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 473.0
SHD2_k127_4286414_3 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 438.0
SHD2_k127_4286414_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 353.0
SHD2_k127_4286414_5 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
SHD2_k127_4286414_6 sulfuric ester hydrolase activity K03760,K19353 - 2.7.8.43 0.000000000000000000000000000000000000000007943 175.0
SHD2_k127_4286414_7 - - - - 0.000000000000000000000000000002044 122.0
SHD2_k127_4286414_8 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000006582 131.0
SHD2_k127_4286414_9 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000002817 120.0
SHD2_k127_4289974_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 594.0
SHD2_k127_4289974_1 Pfam:Kce - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
SHD2_k127_4289974_10 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000001094 192.0
SHD2_k127_4289974_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000001666 185.0
SHD2_k127_4289974_12 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000008161 166.0
SHD2_k127_4289974_13 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000001263 169.0
SHD2_k127_4289974_14 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000000000000000006483 167.0
SHD2_k127_4289974_15 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000003992 126.0
SHD2_k127_4289974_16 metal cluster binding K06940 - - 0.00000000000000000000000000002226 122.0
SHD2_k127_4289974_17 Pfam:N_methyl_2 - - - 0.0000000001283 73.0
SHD2_k127_4289974_18 Lysin motif - - - 0.000000001749 66.0
SHD2_k127_4289974_19 Type II transport protein GspH K08084 - - 0.0000003392 62.0
SHD2_k127_4289974_2 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 353.0
SHD2_k127_4289974_3 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 354.0
SHD2_k127_4289974_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001711 280.0
SHD2_k127_4289974_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001864 287.0
SHD2_k127_4289974_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008697 278.0
SHD2_k127_4289974_7 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008363 261.0
SHD2_k127_4289974_8 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000008471 236.0
SHD2_k127_4289974_9 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000504 214.0
SHD2_k127_4294462_0 all-trans-retinol 13,14-reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 569.0
SHD2_k127_4294462_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 532.0
SHD2_k127_4294462_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 358.0
SHD2_k127_4294462_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 357.0
SHD2_k127_4294462_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004159 261.0
SHD2_k127_4294462_6 CheY-like receiver K02490 - - 0.0000000000009558 73.0
SHD2_k127_4294462_8 antisigma factor binding K03090,K04749,K06378 - - 0.0000003 62.0
SHD2_k127_4329891_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000002032 220.0
SHD2_k127_4329891_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000002049 144.0
SHD2_k127_4332559_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1290.0
SHD2_k127_4332559_1 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1142.0
SHD2_k127_4332559_10 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 539.0
SHD2_k127_4332559_11 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 527.0
SHD2_k127_4332559_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 476.0
SHD2_k127_4332559_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 461.0
SHD2_k127_4332559_14 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
SHD2_k127_4332559_15 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 451.0
SHD2_k127_4332559_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 440.0
SHD2_k127_4332559_17 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 428.0
SHD2_k127_4332559_18 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 407.0
SHD2_k127_4332559_19 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 360.0
SHD2_k127_4332559_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 1.447e-291 904.0
SHD2_k127_4332559_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 331.0
SHD2_k127_4332559_21 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 333.0
SHD2_k127_4332559_22 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001577 287.0
SHD2_k127_4332559_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003902 294.0
SHD2_k127_4332559_24 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004331 280.0
SHD2_k127_4332559_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000677 252.0
SHD2_k127_4332559_27 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000001403 233.0
SHD2_k127_4332559_28 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000002079 200.0
SHD2_k127_4332559_29 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000001704 211.0
SHD2_k127_4332559_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 9.956e-250 780.0
SHD2_k127_4332559_30 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000003489 182.0
SHD2_k127_4332559_31 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000006802 177.0
SHD2_k127_4332559_32 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000003914 158.0
SHD2_k127_4332559_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000138 150.0
SHD2_k127_4332559_34 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000006653 137.0
SHD2_k127_4332559_35 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000001143 132.0
SHD2_k127_4332559_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000006556 133.0
SHD2_k127_4332559_38 Circadian clock protein K08482 - - 0.00014 49.0
SHD2_k127_4332559_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.193e-230 729.0
SHD2_k127_4332559_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.843e-216 675.0
SHD2_k127_4332559_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 1.992e-215 678.0
SHD2_k127_4332559_7 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.254e-210 668.0
SHD2_k127_4332559_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.899e-208 657.0
SHD2_k127_4332559_9 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 617.0
SHD2_k127_4381046_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 448.0
SHD2_k127_4381046_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 422.0
SHD2_k127_4381046_2 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 312.0
SHD2_k127_4381046_3 Uncharacterised protein family UPF0047 - - - 0.000000009175 56.0
SHD2_k127_4381046_4 Protein of unknown function (DUF1059) - - - 0.000002042 52.0
SHD2_k127_4391329_0 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 357.0
SHD2_k127_4391329_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000004161 215.0
SHD2_k127_4391329_2 PFAM chemotaxis sensory transducer K03406 - - 0.00000000001184 66.0
SHD2_k127_4403297_0 Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 372.0
SHD2_k127_4403297_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 333.0
SHD2_k127_4403297_2 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 329.0
SHD2_k127_4403297_3 ubiE/COQ5 methyltransferase family - - - 0.000000002207 68.0
SHD2_k127_4433716_0 Citrate lyase, alpha subunit (CitF) K01067,K18118 - 2.8.3.18,3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000008571 239.0
SHD2_k127_4433716_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000003271 202.0
SHD2_k127_4448706_0 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 477.0
SHD2_k127_4457268_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
SHD2_k127_4457268_1 Dicarboxylate carrier - - - 0.0000000000000000000000000000000000000000000000001165 178.0
SHD2_k127_4457268_2 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000001692 99.0
SHD2_k127_4457268_3 Thioesterase - - - 0.00000000000000000006842 98.0
SHD2_k127_4457268_4 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000003133 88.0
SHD2_k127_4466990_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 7.719e-222 696.0
SHD2_k127_4466990_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 582.0
SHD2_k127_4466990_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 294.0
SHD2_k127_4466990_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 286.0
SHD2_k127_4466990_12 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000004072 259.0
SHD2_k127_4466990_13 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005306 250.0
SHD2_k127_4466990_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000007625 242.0
SHD2_k127_4466990_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000005615 239.0
SHD2_k127_4466990_16 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000002819 233.0
SHD2_k127_4466990_17 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000002083 160.0
SHD2_k127_4466990_18 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000002062 138.0
SHD2_k127_4466990_19 Protein of unknown function (DUF465) K09794 - - 0.00000000001205 67.0
SHD2_k127_4466990_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 525.0
SHD2_k127_4466990_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 509.0
SHD2_k127_4466990_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 464.0
SHD2_k127_4466990_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 439.0
SHD2_k127_4466990_6 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 418.0
SHD2_k127_4466990_7 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 380.0
SHD2_k127_4466990_8 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 328.0
SHD2_k127_4466990_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 304.0
SHD2_k127_4519137_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1014.0
SHD2_k127_4519137_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 421.0
SHD2_k127_4519137_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 352.0
SHD2_k127_4519137_3 Jag_N K06346 - - 0.0000000000000000000000000000000000000000000000000001291 198.0
SHD2_k127_4519137_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001235 108.0
SHD2_k127_4519137_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000001988 101.0
SHD2_k127_4519137_6 Ribosomal protein L34 K02914 - - 0.0000000000824 64.0
SHD2_k127_4539153_0 Helicase associated domain (HA2) Add an annotation K03578,K03579 - 3.6.4.13 0.0 1309.0
SHD2_k127_4539153_1 Heat shock 70 kDa protein K04043 - - 0.0 1028.0
SHD2_k127_4539153_10 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000006496 96.0
SHD2_k127_4539153_11 SEC-C Motif Domain Protein - - - 0.0000000005307 72.0
SHD2_k127_4539153_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.133e-231 726.0
SHD2_k127_4539153_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 562.0
SHD2_k127_4539153_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 370.0
SHD2_k127_4539153_5 Periplasmic binding protein K07121 - - 0.000000000000000000000000000000000000000000000000000000005909 214.0
SHD2_k127_4539153_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000003954 186.0
SHD2_k127_4539153_7 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000001836 186.0
SHD2_k127_4539153_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000001304 148.0
SHD2_k127_4539153_9 PFAM MORN repeat variant - - - 0.0000000000000000000000001124 117.0
SHD2_k127_4602766_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 495.0
SHD2_k127_4602766_1 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 394.0
SHD2_k127_4602766_2 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000007897 134.0
SHD2_k127_4602766_3 - - - - 0.00000000000000000000000000018 122.0
SHD2_k127_4602766_4 - - - - 0.0000000000000000000000003092 113.0
SHD2_k127_4602766_5 - - - - 0.00000000000001651 79.0
SHD2_k127_4602766_6 Belongs to the ompA family K03286 - - 0.0002096 46.0
SHD2_k127_461460_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.285e-271 845.0
SHD2_k127_461460_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 455.0
SHD2_k127_461460_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
SHD2_k127_461460_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000004234 218.0
SHD2_k127_461460_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000001626 120.0
SHD2_k127_461460_5 Protein of unknown function (DUF2889) - - - 0.00000000000000000000001285 108.0
SHD2_k127_461460_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000806 95.0
SHD2_k127_461460_7 VanZ like family - - - 0.000000000000002805 82.0
SHD2_k127_4633011_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 587.0
SHD2_k127_4633011_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 503.0
SHD2_k127_4633011_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000007544 129.0
SHD2_k127_4633011_11 Major Facilitator Superfamily - - - 0.0000000000000000001713 92.0
SHD2_k127_4633011_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 480.0
SHD2_k127_4633011_3 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 358.0
SHD2_k127_4633011_4 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 317.0
SHD2_k127_4633011_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003131 276.0
SHD2_k127_4633011_6 competence protein - - - 0.00000000000000000000000000000000000000000000000000000002396 208.0
SHD2_k127_4633011_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000001473 196.0
SHD2_k127_4633011_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000003846 187.0
SHD2_k127_4633011_9 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000001033 164.0
SHD2_k127_4638681_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 6.204e-207 656.0
SHD2_k127_4638681_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 503.0
SHD2_k127_4638681_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 295.0
SHD2_k127_4638681_3 YGGT family K02221 - - 0.000000000000000000000000000000000009127 142.0
SHD2_k127_4638681_4 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000004893 99.0
SHD2_k127_4638681_5 PFAM DivIVA family protein K04074 - - 0.0002879 54.0
SHD2_k127_4648298_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001126 259.0
SHD2_k127_4648298_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
SHD2_k127_4648298_2 Membrane dipeptidase (Peptidase family M19) - - - 0.000000000000000000000000000000001719 143.0
SHD2_k127_4648298_3 Ferredoxin - - - 0.0000000000000000000000000000001365 130.0
SHD2_k127_4648298_4 Thioesterase K07107 - - 0.00000000000000000000000000001533 123.0
SHD2_k127_4648298_5 - - - - 0.00000000000000000000000000003027 124.0
SHD2_k127_4648298_6 - - - - 0.000000000000004289 81.0
SHD2_k127_4662508_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 621.0
SHD2_k127_4662508_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 484.0
SHD2_k127_4662508_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001119 274.0
SHD2_k127_4662508_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002754 235.0
SHD2_k127_4662508_4 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001461 220.0
SHD2_k127_4662508_5 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000002316 219.0
SHD2_k127_4662508_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000007248 120.0
SHD2_k127_4662508_7 - - - - 0.000000000000000000000000005119 115.0
SHD2_k127_4662508_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002452 69.0
SHD2_k127_4671927_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 473.0
SHD2_k127_4671927_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 459.0
SHD2_k127_4671927_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000001871 118.0
SHD2_k127_4671927_3 Prokaryotic N-terminal methylation motif - - - 0.0001591 47.0
SHD2_k127_4690808_0 Alpha-2-Macroglobulin K06894 - - 0.0 2007.0
SHD2_k127_4690808_1 BadF BadG BcrA BcrD - - - 0.0 1710.0
SHD2_k127_4690808_2 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 2.035e-234 745.0
SHD2_k127_4690808_3 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 479.0
SHD2_k127_4690808_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000111 181.0
SHD2_k127_4690808_5 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0003133 43.0
SHD2_k127_4690808_6 Fe-S oxidoreductase - - - 0.0008741 42.0
SHD2_k127_4709329_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1495.0
SHD2_k127_4709329_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1399.0
SHD2_k127_4709329_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 434.0
SHD2_k127_4709329_11 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 419.0
SHD2_k127_4709329_12 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 393.0
SHD2_k127_4709329_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 314.0
SHD2_k127_4709329_14 Phospholipase D K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001223 272.0
SHD2_k127_4709329_15 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000003635 222.0
SHD2_k127_4709329_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000001219 210.0
SHD2_k127_4709329_17 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000005965 194.0
SHD2_k127_4709329_18 - - - - 0.00000000000000000000000000000000000000000000944 167.0
SHD2_k127_4709329_19 - - - - 0.0000000000000000000000000000000000000002563 156.0
SHD2_k127_4709329_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.869e-269 837.0
SHD2_k127_4709329_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000004796 150.0
SHD2_k127_4709329_21 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000004639 130.0
SHD2_k127_4709329_22 - - - - 0.00000000000000000000001139 112.0
SHD2_k127_4709329_23 phosphorelay signal transduction system K07714 - - 0.0000000000000000005667 91.0
SHD2_k127_4709329_24 HD domain - - - 0.0000000000001063 71.0
SHD2_k127_4709329_25 Thioesterase K15315 - - 0.00000000001945 70.0
SHD2_k127_4709329_26 aminopeptidase activity - - - 0.0000001054 54.0
SHD2_k127_4709329_3 PFAM magnesium chelatase K07391 - - 1.433e-211 668.0
SHD2_k127_4709329_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.273e-201 639.0
SHD2_k127_4709329_5 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 602.0
SHD2_k127_4709329_6 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 544.0
SHD2_k127_4709329_7 Quinone oxidoreductase, YhdH YhfP family K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 445.0
SHD2_k127_4709329_8 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 438.0
SHD2_k127_4709329_9 Signal transduction histidine kinase, nitrogen specific - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 445.0
SHD2_k127_4721032_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 580.0
SHD2_k127_4721032_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 419.0
SHD2_k127_4721032_2 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 352.0
SHD2_k127_4721032_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 307.0
SHD2_k127_4721032_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001249 226.0
SHD2_k127_4721032_5 PQ loop repeat K15383 - - 0.0000000000000001485 86.0
SHD2_k127_4743363_0 PFAM Pyruvate carboxyltransferase - - - 5e-323 999.0
SHD2_k127_4743363_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.738e-233 737.0
SHD2_k127_4743363_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 289.0
SHD2_k127_4772606_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.138e-230 724.0
SHD2_k127_4772606_1 Belongs to the RtcB family K14415 - 6.5.1.3 5.183e-227 711.0
SHD2_k127_4772606_10 Glutaredoxin K03676 - - 0.00000000000000006007 81.0
SHD2_k127_4772606_11 Putative heavy-metal-binding - - - 0.000000005035 63.0
SHD2_k127_4772606_2 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 492.0
SHD2_k127_4772606_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 408.0
SHD2_k127_4772606_4 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003063 272.0
SHD2_k127_4772606_5 PFAM Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000286 221.0
SHD2_k127_4772606_6 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000000611 152.0
SHD2_k127_4772606_8 glutaredoxin-like protein, YruB-family - - - 0.00000000000000000007748 95.0
SHD2_k127_4772606_9 phosphorelay signal transduction system - - - 0.000000000000000006448 89.0
SHD2_k127_4776756_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.625e-254 790.0
SHD2_k127_4776756_1 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 539.0
SHD2_k127_4776756_2 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 522.0
SHD2_k127_4776756_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 495.0
SHD2_k127_4776756_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 464.0
SHD2_k127_4776756_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 404.0
SHD2_k127_4776756_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000001891 197.0
SHD2_k127_4776756_7 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000001888 184.0
SHD2_k127_4776756_8 Protein of unknown function (DUF1285) K09986 - - 0.0000000000000000000000000000000000000005644 155.0
SHD2_k127_4779775_0 MacB-like periplasmic core domain K02004 - - 0.0 1085.0
SHD2_k127_4779775_1 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.0 1033.0
SHD2_k127_4779775_10 GntP family permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 400.0
SHD2_k127_4779775_11 PFAM Xanthine uracil vitamin C permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 374.0
SHD2_k127_4779775_12 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 357.0
SHD2_k127_4779775_13 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 348.0
SHD2_k127_4779775_14 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 342.0
SHD2_k127_4779775_15 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 340.0
SHD2_k127_4779775_16 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
SHD2_k127_4779775_17 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 340.0
SHD2_k127_4779775_18 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 324.0
SHD2_k127_4779775_19 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
SHD2_k127_4779775_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 1.427e-241 770.0
SHD2_k127_4779775_20 helix_turn_helix, Lux Regulon K02479 - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
SHD2_k127_4779775_21 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000009885 239.0
SHD2_k127_4779775_22 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
SHD2_k127_4779775_23 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000009127 238.0
SHD2_k127_4779775_24 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000001607 217.0
SHD2_k127_4779775_25 Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000003746 205.0
SHD2_k127_4779775_26 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000004608 196.0
SHD2_k127_4779775_27 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000006061 194.0
SHD2_k127_4779775_28 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000007895 190.0
SHD2_k127_4779775_29 Cache_2 - - - 0.000000000000000000000000000000000000000000001403 170.0
SHD2_k127_4779775_3 Dicarboxylate carrier - - - 1.558e-214 674.0
SHD2_k127_4779775_30 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000005376 160.0
SHD2_k127_4779775_31 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000005205 153.0
SHD2_k127_4779775_32 DRTGG domain - - - 0.00000000000000000000000000000009488 128.0
SHD2_k127_4779775_33 DRTGG domain - - - 0.0000000000000000000000000000007599 128.0
SHD2_k127_4779775_34 sporulation resulting in formation of a cellular spore K01449 - 3.5.1.28 0.000000000000000000000000001168 129.0
SHD2_k127_4779775_35 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001357 102.0
SHD2_k127_4779775_36 Dodecin K09165 - - 0.000000000000001155 79.0
SHD2_k127_4779775_37 Dodecin K09165 - - 0.000000000000004717 78.0
SHD2_k127_4779775_38 Metal-dependent phosphohydrolase - - - 0.000006599 57.0
SHD2_k127_4779775_4 PFAM Acyl-CoA dehydrogenase K09456 - - 5.396e-199 638.0
SHD2_k127_4779775_5 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 529.0
SHD2_k127_4779775_6 50S ribosome-binding GTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 525.0
SHD2_k127_4779775_7 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 475.0
SHD2_k127_4779775_8 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 460.0
SHD2_k127_4779775_9 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 429.0
SHD2_k127_4787479_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 439.0
SHD2_k127_4787479_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001145 277.0
SHD2_k127_4787479_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000157 136.0
SHD2_k127_4787479_3 Cysteine-rich domain - - - 0.000000000000000000004381 100.0
SHD2_k127_4787479_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.000000000005953 66.0
SHD2_k127_4802069_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.039e-228 715.0
SHD2_k127_4802069_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.242e-208 655.0
SHD2_k127_4802069_2 acyl-coa dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 518.0
SHD2_k127_4802069_3 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 407.0
SHD2_k127_4802069_4 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 403.0
SHD2_k127_4802069_5 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 385.0
SHD2_k127_4802069_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 292.0
SHD2_k127_4802069_7 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000001777 220.0
SHD2_k127_4802069_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000004249 162.0
SHD2_k127_4802069_9 PFAM Enoyl-CoA hydratase isomerase - - - 0.0005261 46.0
SHD2_k127_4814915_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 582.0
SHD2_k127_4814915_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 296.0
SHD2_k127_4814915_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003639 284.0
SHD2_k127_4814915_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000476 149.0
SHD2_k127_4814915_4 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000003327 142.0
SHD2_k127_4814915_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000002101 104.0
SHD2_k127_4814915_6 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000255 90.0
SHD2_k127_4815289_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1253.0
SHD2_k127_4815289_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 566.0
SHD2_k127_4815289_11 PFAM Stage II sporulation protein K06381 - - 0.00000000000000533 76.0
SHD2_k127_4815289_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 437.0
SHD2_k127_4815289_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 396.0
SHD2_k127_4815289_4 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 308.0
SHD2_k127_4815289_5 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000001082 246.0
SHD2_k127_4815289_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000005016 189.0
SHD2_k127_4815289_7 - - - - 0.0000000000000000000000000000000000000001883 159.0
SHD2_k127_4815289_8 HIT family K02503 - - 0.000000000000000000000000000000000000006386 148.0
SHD2_k127_4815289_9 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000001954 138.0
SHD2_k127_4827033_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.925e-321 992.0
SHD2_k127_4827033_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.256e-319 996.0
SHD2_k127_4827033_10 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 378.0
SHD2_k127_4827033_11 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 380.0
SHD2_k127_4827033_12 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 367.0
SHD2_k127_4827033_13 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
SHD2_k127_4827033_14 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 335.0
SHD2_k127_4827033_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004675 273.0
SHD2_k127_4827033_16 WxcM-like, C-terminal K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007527 267.0
SHD2_k127_4827033_17 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000004888 244.0
SHD2_k127_4827033_18 antitermination protein NusG K05785 - - 0.00000000000000000000000000000000000000000000000000000000000000000004705 234.0
SHD2_k127_4827033_19 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
SHD2_k127_4827033_2 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.478e-242 760.0
SHD2_k127_4827033_20 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000003019 216.0
SHD2_k127_4827033_21 system, mannose fructose sorbose family, IID component K02796 - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
SHD2_k127_4827033_22 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000001452 194.0
SHD2_k127_4827033_23 SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000003611 191.0
SHD2_k127_4827033_24 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001979 161.0
SHD2_k127_4827033_25 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000003847 160.0
SHD2_k127_4827033_26 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000249 155.0
SHD2_k127_4827033_27 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000000000000000003253 149.0
SHD2_k127_4827033_28 ACT domain - - - 0.000000000000000000000000000000000006578 140.0
SHD2_k127_4827033_29 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000003563 132.0
SHD2_k127_4827033_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.764e-239 752.0
SHD2_k127_4827033_30 KH domain K06960 - - 0.0000000000000000000000000000000007973 131.0
SHD2_k127_4827033_31 Lipoprotein - - - 0.00000000000000000000000000000000587 139.0
SHD2_k127_4827033_32 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000000006067 122.0
SHD2_k127_4827033_33 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000008242 116.0
SHD2_k127_4827033_34 - - - - 0.000000000000000000000000001502 114.0
SHD2_k127_4827033_35 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000003763 94.0
SHD2_k127_4827033_36 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000005722 96.0
SHD2_k127_4827033_37 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000003361 83.0
SHD2_k127_4827033_38 - - - - 0.0000000000008634 77.0
SHD2_k127_4827033_39 Pfam:N_methyl_2 - - - 0.000000000002148 78.0
SHD2_k127_4827033_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.11e-211 662.0
SHD2_k127_4827033_41 Cell division protein K03591,K03749 - - 0.0000000954 62.0
SHD2_k127_4827033_42 Type II transport protein GspH K08084 - - 0.000002008 57.0
SHD2_k127_4827033_5 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 585.0
SHD2_k127_4827033_6 Signal peptide binding domain K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 509.0
SHD2_k127_4827033_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 482.0
SHD2_k127_4827033_8 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 476.0
SHD2_k127_4827033_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 455.0
SHD2_k127_4860810_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 505.0
SHD2_k127_4860810_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 452.0
SHD2_k127_4860810_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
SHD2_k127_4860810_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 376.0
SHD2_k127_4860810_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000006237 263.0
SHD2_k127_4860810_5 Pfam Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000005542 185.0
SHD2_k127_4860810_6 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000002357 166.0
SHD2_k127_4860810_7 Peptidase C39 family - - - 0.0000000000000000000003708 103.0
SHD2_k127_4869626_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.245e-298 922.0
SHD2_k127_4869626_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 453.0
SHD2_k127_4869626_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 366.0
SHD2_k127_4869626_3 ThiF family K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000005215 210.0
SHD2_k127_4869626_4 - - - - 0.0000000000000000000000000000000006175 139.0
SHD2_k127_4869626_5 Mut7-C ubiquitin - - - 0.00000000000001221 76.0
SHD2_k127_4945585_0 S1, RNA binding domain K06959 - - 0.0 1029.0
SHD2_k127_4945585_1 sigma54 specific transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 516.0
SHD2_k127_4974069_0 Protein of unknown function, DUF484 - - - 0.00000000000000000000000000000006634 134.0
SHD2_k127_4974069_1 response regulator, receiver - - - 0.0000000001294 70.0
SHD2_k127_4974069_2 Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.00000002267 61.0
SHD2_k127_4974069_3 Resolvase, N terminal domain - - - 0.000007932 53.0
SHD2_k127_499625_0 Domain of unknown function (DUF1846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 373.0
SHD2_k127_499625_1 chitinase K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000002494 188.0
SHD2_k127_5009251_0 acetyl-CoA hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 393.0
SHD2_k127_5009251_1 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000001371 213.0
SHD2_k127_5009251_2 Histidine kinase - - - 0.000000000000000000000000000000001153 138.0
SHD2_k127_5009251_3 Belongs to the enoyl-CoA hydratase isomerase family K15016 - 1.1.1.35,4.2.1.17 0.000000000000000000000000000000388 125.0
SHD2_k127_5009251_4 response regulator K07689 - - 0.00000000000000000000000001351 122.0
SHD2_k127_5009251_5 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000003317 86.0
SHD2_k127_5009251_6 His Kinase A (phosphoacceptor) domain K07678 - 2.7.13.3 0.000002079 57.0
SHD2_k127_5086686_0 Protein of unknown function (DUF3141) - - - 2.25e-244 779.0
SHD2_k127_5086686_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 568.0
SHD2_k127_5086686_10 PFAM amino acid-binding ACT domain protein - - - 0.000000000005337 72.0
SHD2_k127_5086686_11 - - - - 0.000000000007431 76.0
SHD2_k127_5086686_2 ABC transporter K02013,K05776 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 441.0
SHD2_k127_5086686_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 377.0
SHD2_k127_5086686_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 347.0
SHD2_k127_5086686_5 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 305.0
SHD2_k127_5086686_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001384 301.0
SHD2_k127_5086686_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005685 278.0
SHD2_k127_5086686_8 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000001026 244.0
SHD2_k127_5086686_9 Protein of unknown function (DUF3024) - - - 0.000000000000000000000000005548 113.0
SHD2_k127_5110902_0 Threonine synthase N terminus K01733 - 4.2.3.1 1.452e-225 706.0
SHD2_k127_5110902_1 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 409.0
SHD2_k127_5110902_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 346.0
SHD2_k127_5110902_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.00000000000000000000000000000000000000004277 154.0
SHD2_k127_5110902_4 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000007797 92.0
SHD2_k127_5150315_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 1.32e-319 997.0
SHD2_k127_5150315_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 361.0
SHD2_k127_5150315_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 356.0
SHD2_k127_5150315_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 275.0
SHD2_k127_5150315_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000002922 225.0
SHD2_k127_5150315_5 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000003594 181.0
SHD2_k127_5150315_7 - - - - 0.000000000000000000000000000000001441 134.0
SHD2_k127_5150315_8 MJ0042 family finger-like protein - - - 0.000000000000000000000000000000008059 139.0
SHD2_k127_5150315_9 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000002618 61.0
SHD2_k127_5166213_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.086e-212 668.0
SHD2_k127_5166213_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 573.0
SHD2_k127_5166213_2 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 529.0
SHD2_k127_5166213_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 448.0
SHD2_k127_5166213_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 378.0
SHD2_k127_5166213_5 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001256 253.0
SHD2_k127_5166213_6 Predicted membrane protein (DUF2232) - - - 0.0000000000000000000000000000000000000000000000000000000002265 214.0
SHD2_k127_5166213_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001543 166.0
SHD2_k127_5166213_8 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000009519 126.0
SHD2_k127_5166213_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002673 115.0
SHD2_k127_5174894_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.346e-260 819.0
SHD2_k127_5174894_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 548.0
SHD2_k127_5174894_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 479.0
SHD2_k127_5174894_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 471.0
SHD2_k127_5174894_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 402.0
SHD2_k127_5174894_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
SHD2_k127_5174894_6 Virulence activator alpha C-term - - - 0.00000000000000000000000000000000000000000000000000000001092 202.0
SHD2_k127_5174894_7 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000001219 153.0
SHD2_k127_521519_0 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 342.0
SHD2_k127_521519_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 316.0
SHD2_k127_521519_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 300.0
SHD2_k127_521519_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
SHD2_k127_5293965_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.216e-233 727.0
SHD2_k127_5293965_1 PFAM MgsA AAA ATPase C terminal K07478 - - 6.558e-201 634.0
SHD2_k127_5293965_10 Arylsulfotransferase (ASST) - - - 0.00000000000000000000001024 104.0
SHD2_k127_5293965_11 PspC domain - - - 0.0000000000000000002621 89.0
SHD2_k127_5293965_12 Putative regulatory protein - - - 0.00000000000005592 73.0
SHD2_k127_5293965_13 Amidohydrolase - - - 0.0001278 45.0
SHD2_k127_5293965_2 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 511.0
SHD2_k127_5293965_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 483.0
SHD2_k127_5293965_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 445.0
SHD2_k127_5293965_5 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 389.0
SHD2_k127_5293965_6 PrpF protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 304.0
SHD2_k127_5293965_7 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 285.0
SHD2_k127_5293965_8 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000001242 237.0
SHD2_k127_5293965_9 NTPase - - - 0.000000000000000000000000000000000000009153 151.0
SHD2_k127_5318643_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.005e-212 676.0
SHD2_k127_5318643_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 2.053e-194 616.0
SHD2_k127_5318643_2 Proposed homoserine kinase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 540.0
SHD2_k127_5318643_3 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 401.0
SHD2_k127_5318643_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000006661 199.0
SHD2_k127_5318643_5 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000000007727 132.0
SHD2_k127_5318643_6 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000004803 124.0
SHD2_k127_5327033_0 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000001529 219.0
SHD2_k127_5327033_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.000000000000000000000000000000000000000000000000204 181.0
SHD2_k127_5374707_0 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 461.0
SHD2_k127_5374707_1 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 336.0
SHD2_k127_5374707_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21030 - 2.7.7.40,2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000002919 239.0
SHD2_k127_5374707_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000003974 211.0
SHD2_k127_5400913_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.675e-283 883.0
SHD2_k127_5400913_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.598e-262 816.0
SHD2_k127_5400913_10 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 312.0
SHD2_k127_5400913_11 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 282.0
SHD2_k127_5400913_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000002819 229.0
SHD2_k127_5400913_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002316 235.0
SHD2_k127_5400913_14 - - - - 0.00000000000000000000000000000000000000000000000000002584 196.0
SHD2_k127_5400913_15 Thioesterase K07107 - - 0.00000000000000000000000000000000000000001146 157.0
SHD2_k127_5400913_16 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000004078 135.0
SHD2_k127_5400913_17 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000001498 120.0
SHD2_k127_5400913_18 Gaf domain - - - 0.00000000000000000000003045 118.0
SHD2_k127_5400913_19 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000002054 98.0
SHD2_k127_5400913_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 9.171e-207 658.0
SHD2_k127_5400913_20 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000214 87.0
SHD2_k127_5400913_21 LuxR family transcriptional regulator K04333,K20918 - - 0.00000000000005392 81.0
SHD2_k127_5400913_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 524.0
SHD2_k127_5400913_4 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 522.0
SHD2_k127_5400913_5 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 517.0
SHD2_k127_5400913_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 469.0
SHD2_k127_5400913_7 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 356.0
SHD2_k127_5400913_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 342.0
SHD2_k127_5400913_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 374.0
SHD2_k127_5409934_0 PFAM EAL domain - - - 1.187e-216 694.0
SHD2_k127_5409934_1 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 422.0
SHD2_k127_5436883_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 577.0
SHD2_k127_5436883_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 431.0
SHD2_k127_5436883_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 360.0
SHD2_k127_5436883_3 outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000001606 81.0
SHD2_k127_5436883_4 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000001418 72.0
SHD2_k127_5469248_0 DSHCT - - - 9.402e-255 804.0
SHD2_k127_5469248_1 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 9.355e-235 745.0
SHD2_k127_5469248_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 343.0
SHD2_k127_5469248_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 339.0
SHD2_k127_5469248_12 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 294.0
SHD2_k127_5469248_13 Protein of unknown function (DUF554) K07150 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005678 275.0
SHD2_k127_5469248_14 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000001454 264.0
SHD2_k127_5469248_15 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000399 214.0
SHD2_k127_5469248_16 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000154 198.0
SHD2_k127_5469248_17 Fimbrial assembly family protein K02461 - - 0.000000000000000000000000000000000000345 162.0
SHD2_k127_5469248_18 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000003629 100.0
SHD2_k127_5469248_19 protein transport across the cell outer membrane K02457,K08084 - - 0.00000000000000000001188 100.0
SHD2_k127_5469248_2 PFAM Type II secretion system protein E K02454 - - 5.808e-212 673.0
SHD2_k127_5469248_20 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000000002887 103.0
SHD2_k127_5469248_21 peptidyl-tyrosine sulfation - - - 0.000000000000000002763 93.0
SHD2_k127_5469248_22 general secretion pathway protein K02457,K02459,K10927,K12285 - - 0.000000000000000161 89.0
SHD2_k127_5469248_23 - - - - 0.000000000000001407 88.0
SHD2_k127_5469248_24 - - - - 0.00000000000008668 81.0
SHD2_k127_5469248_25 protein transport across the cell outer membrane K02452,K02463 - - 0.0000000002722 71.0
SHD2_k127_5469248_28 Prokaryotic N-terminal methylation motif K02458 - - 0.0000002692 60.0
SHD2_k127_5469248_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 595.0
SHD2_k127_5469248_4 amidohydrolase K12940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 552.0
SHD2_k127_5469248_5 type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 560.0
SHD2_k127_5469248_6 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 506.0
SHD2_k127_5469248_7 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 417.0
SHD2_k127_5469248_8 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 411.0
SHD2_k127_5469248_9 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 357.0
SHD2_k127_5507736_0 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 543.0
SHD2_k127_5507736_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 459.0
SHD2_k127_5507736_2 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 415.0
SHD2_k127_5507736_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 400.0
SHD2_k127_5507736_4 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 362.0
SHD2_k127_5507736_5 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 256.0
SHD2_k127_5507736_6 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000004872 178.0
SHD2_k127_5507736_7 Domain of unknown function (DUF3578) - - - 0.000000000000000000000000007508 122.0
SHD2_k127_5542260_0 DNA polymerase A domain K02335 - 2.7.7.7 5.067e-216 693.0
SHD2_k127_5542260_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.413e-215 678.0
SHD2_k127_5542260_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 467.0
SHD2_k127_5542260_3 secreted Zn-dependent protease - - - 0.0000003782 60.0
SHD2_k127_5542260_4 - - - - 0.00007814 47.0
SHD2_k127_5551177_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
SHD2_k127_5551177_1 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 354.0
SHD2_k127_5551177_2 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000497 274.0
SHD2_k127_5551177_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
SHD2_k127_5551177_4 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000002914 229.0
SHD2_k127_5551177_5 RDD family - - - 0.000000000000000000000000000000000000000128 156.0
SHD2_k127_5551177_6 hmm pf04305 - - - 0.0000008834 50.0
SHD2_k127_5561499_0 Major facilitator Superfamily - - - 1.053e-201 639.0
SHD2_k127_5561499_1 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 495.0
SHD2_k127_5561499_10 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005093 291.0
SHD2_k127_5561499_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 275.0
SHD2_k127_5561499_12 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000007911 265.0
SHD2_k127_5561499_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
SHD2_k127_5561499_14 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000001859 227.0
SHD2_k127_5561499_15 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000002736 161.0
SHD2_k127_5561499_16 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000004019 144.0
SHD2_k127_5561499_17 - - - - 0.0000000000000000000000000324 117.0
SHD2_k127_5561499_18 Histidine kinase K02491 - 2.7.13.3 0.0000000000000000007956 101.0
SHD2_k127_5561499_19 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000001072 76.0
SHD2_k127_5561499_2 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 437.0
SHD2_k127_5561499_3 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 415.0
SHD2_k127_5561499_4 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 363.0
SHD2_k127_5561499_5 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 342.0
SHD2_k127_5561499_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 340.0
SHD2_k127_5561499_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 333.0
SHD2_k127_5561499_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 319.0
SHD2_k127_5561499_9 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 306.0
SHD2_k127_5573526_0 Flagellar M-ring protein C-terminal K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 503.0
SHD2_k127_5573526_1 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 450.0
SHD2_k127_5573526_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 325.0
SHD2_k127_5573526_3 Flagella basal body rod protein K02388 - - 0.0000000000000000000000000000000000000000000000000003514 191.0
SHD2_k127_5573526_4 protein trimerization - - - 0.00000000000000000000000000003627 129.0
SHD2_k127_5573526_5 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000002634 99.0
SHD2_k127_5573526_6 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000003039 87.0
SHD2_k127_5573526_7 FliG middle domain K02410 - - 0.00000000000001639 74.0
SHD2_k127_5609543_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 2.164e-258 804.0
SHD2_k127_5609543_1 D-galactarate dehydratase altronate hydrolase domain protein K16850 - 4.2.1.7 9.91e-199 624.0
SHD2_k127_5609543_2 Transcriptional regulator K02624 - - 0.000000000000000000000000000000000000001797 157.0
SHD2_k127_5609543_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000001259 137.0
SHD2_k127_5609543_4 SAF - - - 0.000000000000000000000000000002219 122.0
SHD2_k127_5611359_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.167e-243 778.0
SHD2_k127_5611359_1 DHH family K07462 - - 6.842e-226 713.0
SHD2_k127_5611359_10 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001078 245.0
SHD2_k127_5611359_11 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000002282 216.0
SHD2_k127_5611359_12 SCO1/SenC - - - 0.00000000000000000000000000000000000000000000000000000001092 202.0
SHD2_k127_5611359_13 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000002516 175.0
SHD2_k127_5611359_14 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000003936 122.0
SHD2_k127_5611359_15 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000005533 98.0
SHD2_k127_5611359_16 Domain of unknown function (DUF4911) - - - 0.000000001953 63.0
SHD2_k127_5611359_2 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 588.0
SHD2_k127_5611359_3 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 565.0
SHD2_k127_5611359_4 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 463.0
SHD2_k127_5611359_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 357.0
SHD2_k127_5611359_6 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 361.0
SHD2_k127_5611359_7 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 328.0
SHD2_k127_5611359_8 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000384 278.0
SHD2_k127_5611359_9 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001353 279.0
SHD2_k127_5657488_0 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001654 258.0
SHD2_k127_5657488_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000003474 162.0
SHD2_k127_5657488_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000005758 66.0
SHD2_k127_5703779_0 Carbamoyltransferase C-terminus K00612 - - 1.744e-251 785.0
SHD2_k127_5703779_1 Transglutaminase/protease-like homologues - - - 0.00000000000000009618 87.0
SHD2_k127_5706688_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1835.0
SHD2_k127_5706688_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 345.0
SHD2_k127_5706688_2 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000001516 215.0
SHD2_k127_5706688_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000004555 185.0
SHD2_k127_5706688_4 - - - - 0.0000000000000000000000000000000000001949 147.0
SHD2_k127_5706688_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000007846 64.0
SHD2_k127_5706688_6 Transposase and inactivated derivatives - - - 0.0003092 49.0
SHD2_k127_5708846_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 535.0
SHD2_k127_5708846_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 458.0
SHD2_k127_5708846_10 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000001409 141.0
SHD2_k127_5708846_11 Predicted permease K07089 - - 0.00000000000000000000000000000000004851 137.0
SHD2_k127_5708846_12 Thioredoxin K03671 - - 0.00000000000000000000000000000000009459 137.0
SHD2_k127_5708846_13 redox-active disulfide protein 2 - - - 0.00000000000000000000001114 104.0
SHD2_k127_5708846_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000168 71.0
SHD2_k127_5708846_2 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 349.0
SHD2_k127_5708846_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 344.0
SHD2_k127_5708846_4 pyrroline-5-carboxylate reductase activity K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 303.0
SHD2_k127_5708846_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000003639 225.0
SHD2_k127_5708846_6 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000334 182.0
SHD2_k127_5708846_7 regulatory protein, arsR K03892 - - 0.000000000000000000000000000000000000000003701 157.0
SHD2_k127_5708846_8 DGC domain protein - - - 0.0000000000000000000000000000000000000003525 153.0
SHD2_k127_5708846_9 Thioredoxin domain - - - 0.000000000000000000000000000000000000002267 152.0
SHD2_k127_5732562_0 Ftsk_gamma K03466 - - 3.766e-238 758.0
SHD2_k127_5732562_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 412.0
SHD2_k127_5732562_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005093 285.0
SHD2_k127_5732562_3 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003644 265.0
SHD2_k127_5732562_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000003837 257.0
SHD2_k127_5732562_5 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000002847 199.0
SHD2_k127_5732562_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000002917 182.0
SHD2_k127_5732562_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000001237 81.0
SHD2_k127_5732562_8 Helix-turn-helix domain - - - 0.00000000001363 73.0
SHD2_k127_5732562_9 SEC-C motif - - - 0.000001416 52.0
SHD2_k127_5746979_0 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 475.0
SHD2_k127_5746979_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000135 240.0
SHD2_k127_5746979_2 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000579 137.0
SHD2_k127_5763911_0 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 362.0
SHD2_k127_5763911_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 304.0
SHD2_k127_5763911_2 acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001416 231.0
SHD2_k127_5801338_0 Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005635 285.0
SHD2_k127_5801338_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000006171 263.0
SHD2_k127_5801808_0 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000001685 235.0
SHD2_k127_5801808_1 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000003068 229.0
SHD2_k127_5801808_2 - - - - 0.000000000009475 72.0
SHD2_k127_5808896_0 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 304.0
SHD2_k127_5808896_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 320.0
SHD2_k127_5808896_2 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002237 272.0
SHD2_k127_5808896_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 265.0
SHD2_k127_5808896_4 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000004387 270.0
SHD2_k127_5808896_5 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008071 260.0
SHD2_k127_5808896_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000003834 206.0
SHD2_k127_5808896_7 diguanylate cyclase - - - 0.00000000000000000000005125 102.0
SHD2_k127_5808896_8 Domain of unknown function (DUF4340) - - - 0.000001322 61.0
SHD2_k127_586109_0 alkaline phosphatase activity K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 420.0
SHD2_k127_586109_1 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003022 256.0
SHD2_k127_586109_2 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000007772 185.0
SHD2_k127_5923752_0 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 334.0
SHD2_k127_5923752_1 Diguanylate cyclase K21084 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000006589 201.0
SHD2_k127_5923752_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000002654 145.0
SHD2_k127_5923752_3 protein kinase activity - - - 0.0000000000000000000000000000751 125.0
SHD2_k127_5939260_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.163e-315 974.0
SHD2_k127_5939260_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 597.0
SHD2_k127_5939260_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 445.0
SHD2_k127_5939260_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
SHD2_k127_5939260_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000112 175.0
SHD2_k127_5939260_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000002472 105.0
SHD2_k127_5941970_0 Sulfatase - - - 4.556e-216 688.0
SHD2_k127_5941970_1 acyl-coa dehydrogenase - - - 3.199e-213 668.0
SHD2_k127_5941970_10 SMART Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001313 251.0
SHD2_k127_5941970_11 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001785 249.0
SHD2_k127_5941970_12 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009326 243.0
SHD2_k127_5941970_13 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002164 243.0
SHD2_k127_5941970_15 - - - - 0.0000000000000000000000000000000000000000000000000000000001766 216.0
SHD2_k127_5941970_16 Guanosine polyphosphate - - - 0.0000000000000000000000000000000000000000000000000000002217 199.0
SHD2_k127_5941970_17 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000009356 174.0
SHD2_k127_5941970_18 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000006344 156.0
SHD2_k127_5941970_19 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000009395 134.0
SHD2_k127_5941970_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 473.0
SHD2_k127_5941970_20 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000002924 141.0
SHD2_k127_5941970_21 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.0000000000000000000000000000002338 125.0
SHD2_k127_5941970_22 nitroreductase - - - 0.000000000000000000000000000003545 128.0
SHD2_k127_5941970_23 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000002164 115.0
SHD2_k127_5941970_25 - - - - 0.000000000000000000000003594 108.0
SHD2_k127_5941970_26 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000004159 71.0
SHD2_k127_5941970_27 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000002817 64.0
SHD2_k127_5941970_29 PFAM Tetratricopeptide - - - 0.00001833 55.0
SHD2_k127_5941970_3 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 464.0
SHD2_k127_5941970_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 389.0
SHD2_k127_5941970_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 362.0
SHD2_k127_5941970_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 359.0
SHD2_k127_5941970_7 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 325.0
SHD2_k127_5941970_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 290.0
SHD2_k127_5941970_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001846 283.0
SHD2_k127_5970468_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 1.003e-221 698.0
SHD2_k127_6002140_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1059.0
SHD2_k127_6002140_1 CoA-transferase activity K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 409.0
SHD2_k127_6002140_2 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 321.0
SHD2_k127_6002140_3 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000003033 196.0
SHD2_k127_6002140_4 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000001301 109.0
SHD2_k127_6002140_6 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000003757 67.0
SHD2_k127_6079855_0 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 409.0
SHD2_k127_6079855_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
SHD2_k127_6079855_2 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000000000002577 178.0
SHD2_k127_6079855_3 Dynamin family - - - 0.00001516 49.0
SHD2_k127_6110738_0 Domain of unknown function (DUF3536) - - - 1.462e-296 930.0
SHD2_k127_6110738_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 2.036e-290 910.0
SHD2_k127_6110738_10 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
SHD2_k127_6110738_11 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001057 244.0
SHD2_k127_6110738_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001361 248.0
SHD2_k127_6110738_13 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000003977 241.0
SHD2_k127_6110738_14 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000003562 207.0
SHD2_k127_6110738_15 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000457 202.0
SHD2_k127_6110738_16 trehalose biosynthetic process K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000003099 180.0
SHD2_k127_6110738_17 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000001528 169.0
SHD2_k127_6110738_18 Alkylmercury lyase - - - 0.0000000000000000002438 90.0
SHD2_k127_6110738_2 Alpha amylase, catalytic domain K06044 - 5.4.99.15 4.281e-273 868.0
SHD2_k127_6110738_20 Alkylmercury lyase - - - 0.000000000003416 68.0
SHD2_k127_6110738_21 - - - - 0.000000000007499 69.0
SHD2_k127_6110738_22 - - - - 0.00000000001467 69.0
SHD2_k127_6110738_23 Transglycosylase - - - 0.00000001928 65.0
SHD2_k127_6110738_24 YtxH-like protein - - - 0.0000002827 57.0
SHD2_k127_6110738_25 - - - - 0.0006809 48.0
SHD2_k127_6110738_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 3.768e-225 713.0
SHD2_k127_6110738_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 594.0
SHD2_k127_6110738_5 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 538.0
SHD2_k127_6110738_6 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 537.0
SHD2_k127_6110738_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 477.0
SHD2_k127_6110738_8 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008186 274.0
SHD2_k127_6110738_9 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001302 269.0
SHD2_k127_6127991_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1432.0
SHD2_k127_6127991_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.034e-293 906.0
SHD2_k127_6127991_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 369.0
SHD2_k127_6127991_11 Bacterial extracellular solute-binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 345.0
SHD2_k127_6127991_12 PFAM response regulator receiver K07657,K07659,K07664,K11329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 312.0
SHD2_k127_6127991_13 PhoU domain K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 295.0
SHD2_k127_6127991_14 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001009 238.0
SHD2_k127_6127991_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000001736 159.0
SHD2_k127_6127991_16 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000864 177.0
SHD2_k127_6127991_17 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000093 138.0
SHD2_k127_6127991_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 8.123e-204 642.0
SHD2_k127_6127991_3 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 556.0
SHD2_k127_6127991_4 SMART Nucleotide binding protein, PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 537.0
SHD2_k127_6127991_5 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 453.0
SHD2_k127_6127991_6 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 451.0
SHD2_k127_6127991_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 442.0
SHD2_k127_6127991_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 454.0
SHD2_k127_6127991_9 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 417.0
SHD2_k127_6135463_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 3.946e-194 620.0
SHD2_k127_6135463_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 524.0
SHD2_k127_6135463_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 273.0
SHD2_k127_6135463_3 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000002043 223.0
SHD2_k127_6135463_4 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000006932 222.0
SHD2_k127_6135463_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000003047 183.0
SHD2_k127_6135463_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000004819 173.0
SHD2_k127_6135463_7 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000007353 167.0
SHD2_k127_6135463_8 phosphorelay signal transduction system - - - 0.000000000000000000000000002846 117.0
SHD2_k127_6189360_0 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 575.0
SHD2_k127_6189360_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 517.0
SHD2_k127_6189360_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 476.0
SHD2_k127_6189360_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 432.0
SHD2_k127_6189360_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 405.0
SHD2_k127_6189360_5 PFAM CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 276.0
SHD2_k127_6189360_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000002025 136.0
SHD2_k127_6189360_7 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000008825 108.0
SHD2_k127_6203527_0 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 514.0
SHD2_k127_6203527_1 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005379 237.0
SHD2_k127_6203527_2 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000002343 148.0
SHD2_k127_620865_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.78e-281 876.0
SHD2_k127_620865_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 457.0
SHD2_k127_620865_2 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000002351 241.0
SHD2_k127_620865_3 PFAM Cache, type 2 - - - 0.00000000000000000000000000000000001161 149.0
SHD2_k127_620865_4 SMART Elongator protein 3 MiaB NifB K07139 - - 0.000000001871 59.0
SHD2_k127_631481_0 PFAM Type II secretion system protein E K02652 - - 3.334e-206 657.0
SHD2_k127_631481_1 Type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 519.0
SHD2_k127_631481_10 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 304.0
SHD2_k127_631481_11 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001516 294.0
SHD2_k127_631481_12 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 266.0
SHD2_k127_631481_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000006824 228.0
SHD2_k127_631481_14 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000006346 200.0
SHD2_k127_631481_15 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000002619 184.0
SHD2_k127_631481_16 Glycosyl transferase, family 2 K12990 - - 0.000000000000000000000000000000000000000000001263 176.0
SHD2_k127_631481_17 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.0000000000000000000000000000000000000000009979 162.0
SHD2_k127_631481_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000003399 149.0
SHD2_k127_631481_19 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000000000000000000002747 143.0
SHD2_k127_631481_2 PFAM type II secretion system K02653,K12278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 464.0
SHD2_k127_631481_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000005659 139.0
SHD2_k127_631481_21 - - - - 0.00000000000000000000431 104.0
SHD2_k127_631481_22 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000005414 96.0
SHD2_k127_631481_23 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000005041 86.0
SHD2_k127_631481_24 Prokaryotic N-terminal methylation motif - - - 0.0000000000005985 74.0
SHD2_k127_631481_25 - - - - 0.00000000004283 72.0
SHD2_k127_631481_26 - - - - 0.0000007079 57.0
SHD2_k127_631481_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 463.0
SHD2_k127_631481_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 457.0
SHD2_k127_631481_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 414.0
SHD2_k127_631481_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 409.0
SHD2_k127_631481_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 362.0
SHD2_k127_631481_8 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 345.0
SHD2_k127_631481_9 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 313.0
SHD2_k127_6356148_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 1.685e-271 854.0
SHD2_k127_6356148_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 474.0
SHD2_k127_6356148_10 - - - - 0.0000000000009377 68.0
SHD2_k127_6356148_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 378.0
SHD2_k127_6356148_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 370.0
SHD2_k127_6356148_4 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 355.0
SHD2_k127_6356148_5 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000005153 223.0
SHD2_k127_6356148_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000005332 226.0
SHD2_k127_6356148_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000001762 213.0
SHD2_k127_6356148_8 RuvA, C-terminal domain K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000004036 185.0
SHD2_k127_6356148_9 Alpha/beta hydrolase family - - - 0.0000000000000000000000006194 109.0
SHD2_k127_6356310_0 PFAM cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 587.0
SHD2_k127_6356310_1 PFAM cytochrome bd ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 304.0
SHD2_k127_6356310_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001402 256.0
SHD2_k127_6356310_3 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000002865 143.0
SHD2_k127_6417926_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 379.0
SHD2_k127_6417926_1 abc transporter, permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 332.0
SHD2_k127_6417926_2 Molybdopterin-binding domain of aldehyde dehydrogenase K20448 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 295.0
SHD2_k127_6417926_3 transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000473 277.0
SHD2_k127_6417926_4 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000007349 202.0
SHD2_k127_6418262_0 CoA binding domain K01905,K22224 - 6.2.1.13 3.667e-202 649.0
SHD2_k127_6418262_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009176 255.0
SHD2_k127_6465340_0 4Fe-4S binding domain - - - 7.466e-213 676.0
SHD2_k127_6465340_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 558.0
SHD2_k127_6465340_10 Domain of unknown function (DUF362) K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 267.0
SHD2_k127_6465340_11 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000006132 198.0
SHD2_k127_6465340_12 Cysteine dioxygenase type I - - - 0.000000000000000000000000000000000000000000000000000001128 203.0
SHD2_k127_6465340_13 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000001205 179.0
SHD2_k127_6465340_15 PFAM pyridoxamine 5-phosphate oxidase-related FMN-binding - - - 0.0000000000000000000000000000000000000000003097 163.0
SHD2_k127_6465340_16 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000014 161.0
SHD2_k127_6465340_17 GDP-mannose mannosyl hydrolase activity K03574,K08320 - 3.6.1.55,3.6.1.65 0.0000000000000000000000000000000000006063 143.0
SHD2_k127_6465340_18 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000003245 145.0
SHD2_k127_6465340_19 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000006677 115.0
SHD2_k127_6465340_2 PFAM DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 545.0
SHD2_k127_6465340_20 - - - - 0.0000000001011 66.0
SHD2_k127_6465340_21 Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein K08364 - - 0.0002429 45.0
SHD2_k127_6465340_3 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 449.0
SHD2_k127_6465340_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 428.0
SHD2_k127_6465340_5 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 426.0
SHD2_k127_6465340_6 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 390.0
SHD2_k127_6465340_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 389.0
SHD2_k127_6465340_8 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 367.0
SHD2_k127_6465340_9 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 293.0
SHD2_k127_6474285_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.771e-286 899.0
SHD2_k127_6474285_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 533.0
SHD2_k127_6474285_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 304.0
SHD2_k127_6474484_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 398.0
SHD2_k127_6474484_1 LysM domain - - - 0.0000000000000000000000000000000000000000006755 170.0
SHD2_k127_6480894_0 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 476.0
SHD2_k127_6480894_1 Elongator protein 3, MiaB family, Radical SAM K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 427.0
SHD2_k127_6480894_10 - - - - 0.0000000003303 64.0
SHD2_k127_6480894_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 376.0
SHD2_k127_6480894_3 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 370.0
SHD2_k127_6480894_4 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 293.0
SHD2_k127_6480894_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000022 284.0
SHD2_k127_6480894_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002871 235.0
SHD2_k127_6480894_7 acyl-coa hydrolase K01073 - 3.1.2.20 0.0000000000000000000000000000000000000000000000000004394 187.0
SHD2_k127_6480894_8 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000006278 187.0
SHD2_k127_6480894_9 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000000000000004198 177.0
SHD2_k127_6486212_0 Domain of unknown function (DUF2088) - - - 2.392e-202 637.0
SHD2_k127_6486212_1 Tripartite ATP-independent periplasmic transporter, DctM component K21393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 378.0
SHD2_k127_6486212_2 C4-dicarboxylate ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 320.0
SHD2_k127_6486212_3 transporter solute receptor, DctP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003709 286.0
SHD2_k127_6486212_4 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 267.0
SHD2_k127_6486212_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000009442 73.0
SHD2_k127_6511870_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.53e-291 906.0
SHD2_k127_6511870_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 514.0
SHD2_k127_6511870_2 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 439.0
SHD2_k127_6511870_3 LigT like Phosphoesterase K01975 - 3.1.4.58 0.000000000000000000000000000000000000002504 153.0
SHD2_k127_6511870_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000005643 148.0
SHD2_k127_6511870_5 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000001 139.0
SHD2_k127_6511870_6 RecX family K03565 - - 0.0000000000000000000003744 102.0
SHD2_k127_6568573_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1334.0
SHD2_k127_6568573_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1013.0
SHD2_k127_6568573_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
SHD2_k127_6568573_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 310.0
SHD2_k127_6568573_12 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 298.0
SHD2_k127_6568573_13 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007263 264.0
SHD2_k127_6568573_14 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000001093 247.0
SHD2_k127_6568573_15 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000008589 147.0
SHD2_k127_6568573_16 protein import - - - 0.0000000000001404 84.0
SHD2_k127_6568573_17 Ferredoxin K05337 - - 0.0000005099 54.0
SHD2_k127_6568573_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 535.0
SHD2_k127_6568573_20 - - - - 0.0003521 45.0
SHD2_k127_6568573_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 535.0
SHD2_k127_6568573_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 533.0
SHD2_k127_6568573_5 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 495.0
SHD2_k127_6568573_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009751 507.0
SHD2_k127_6568573_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 394.0
SHD2_k127_6568573_8 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 387.0
SHD2_k127_6568573_9 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 333.0
SHD2_k127_6574501_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 1.442e-293 915.0
SHD2_k127_6574501_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 8.087e-216 688.0
SHD2_k127_6574501_2 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 344.0
SHD2_k127_6574501_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000001769 186.0
SHD2_k127_6574501_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000008457 123.0
SHD2_k127_6596275_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 573.0
SHD2_k127_6596275_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 514.0
SHD2_k127_6596275_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 484.0
SHD2_k127_6596275_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 317.0
SHD2_k127_6596275_4 Indole-3-glycerol phosphate synthase K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000001781 269.0
SHD2_k127_6596275_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000242 226.0
SHD2_k127_6643834_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.659e-293 913.0
SHD2_k127_6643834_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 556.0
SHD2_k127_6643834_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
SHD2_k127_6643834_11 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000217 239.0
SHD2_k127_6643834_12 PFAM Bile acid sodium symporter K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000009058 235.0
SHD2_k127_6643834_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000001127 222.0
SHD2_k127_6643834_14 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000002315 220.0
SHD2_k127_6643834_15 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000545 213.0
SHD2_k127_6643834_16 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000003159 215.0
SHD2_k127_6643834_17 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000005613 194.0
SHD2_k127_6643834_18 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000000000000754 186.0
SHD2_k127_6643834_19 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000000000000000000004654 186.0
SHD2_k127_6643834_2 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 537.0
SHD2_k127_6643834_20 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000001008 185.0
SHD2_k127_6643834_21 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000007573 188.0
SHD2_k127_6643834_22 diguanylate cyclase - - - 0.0000000000000000000000000000000000001742 153.0
SHD2_k127_6643834_23 TonB C terminal K03832 - - 0.0000000000000000000000000000000006692 150.0
SHD2_k127_6643834_24 OmpA family K03640 - - 0.000000000000000000000000000000001617 137.0
SHD2_k127_6643834_25 PAS domain - - - 0.0000000000000000000000000000006636 127.0
SHD2_k127_6643834_27 - - - - 0.00000000001742 70.0
SHD2_k127_6643834_28 Methyltransferase domain - - - 0.0007427 42.0
SHD2_k127_6643834_3 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 502.0
SHD2_k127_6643834_4 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 459.0
SHD2_k127_6643834_5 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 444.0
SHD2_k127_6643834_6 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 428.0
SHD2_k127_6643834_7 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 385.0
SHD2_k127_6643834_8 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
SHD2_k127_6643834_9 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003428 272.0
SHD2_k127_6681356_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 1.193e-262 813.0
SHD2_k127_6681356_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 272.0
SHD2_k127_6681356_2 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000008264 198.0
SHD2_k127_6723260_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1096.0
SHD2_k127_6723260_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 618.0
SHD2_k127_6723260_10 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000001383 163.0
SHD2_k127_6723260_2 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 530.0
SHD2_k127_6723260_3 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000154 281.0
SHD2_k127_6723260_4 Chemotaxis phosphatase CheX K03409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006794 242.0
SHD2_k127_6723260_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000002861 237.0
SHD2_k127_6723260_6 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
SHD2_k127_6723260_7 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000001654 208.0
SHD2_k127_6723260_8 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000007201 192.0
SHD2_k127_6723260_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000003763 198.0
SHD2_k127_6747535_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.111e-272 843.0
SHD2_k127_6747535_1 acetyl-CoA K18122 - - 4.38e-270 837.0
SHD2_k127_6747535_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 389.0
SHD2_k127_6747535_11 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 396.0
SHD2_k127_6747535_12 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 345.0
SHD2_k127_6747535_13 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 344.0
SHD2_k127_6747535_14 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 329.0
SHD2_k127_6747535_15 ErfK YbiS YcfS YnhG family protein K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
SHD2_k127_6747535_16 GPR1/FUN34/yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005798 274.0
SHD2_k127_6747535_17 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
SHD2_k127_6747535_18 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000006165 233.0
SHD2_k127_6747535_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000001384 211.0
SHD2_k127_6747535_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.274e-264 818.0
SHD2_k127_6747535_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000003496 201.0
SHD2_k127_6747535_21 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000000000000000000001927 186.0
SHD2_k127_6747535_22 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000009548 169.0
SHD2_k127_6747535_23 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000001603 168.0
SHD2_k127_6747535_24 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000002264 159.0
SHD2_k127_6747535_25 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000000001294 152.0
SHD2_k127_6747535_26 Polymer-forming cytoskeletal - - - 0.000000000000000000001891 99.0
SHD2_k127_6747535_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000004558 94.0
SHD2_k127_6747535_29 universal stress protein family - - - 0.000000635 57.0
SHD2_k127_6747535_3 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 1.633e-229 726.0
SHD2_k127_6747535_4 Required for chromosome condensation and partitioning K03529 - - 3.482e-204 679.0
SHD2_k127_6747535_5 PFAM Citrate transporter - - - 6.555e-204 649.0
SHD2_k127_6747535_6 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 565.0
SHD2_k127_6747535_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 493.0
SHD2_k127_6747535_8 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 435.0
SHD2_k127_6747535_9 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 424.0
SHD2_k127_6750292_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.226e-273 853.0
SHD2_k127_6750292_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000205 50.0
SHD2_k127_6763876_0 Bacterial regulatory protein, Fis family - - - 1.593e-203 642.0
SHD2_k127_6763876_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 486.0
SHD2_k127_6763876_10 Heavy-metal resistance - - - 0.000009185 54.0
SHD2_k127_6763876_2 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 424.0
SHD2_k127_6763876_3 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 419.0
SHD2_k127_6763876_4 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 327.0
SHD2_k127_6763876_5 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002996 294.0
SHD2_k127_6763876_6 Rubrerythrin - - - 0.0000000000000000000000000000000000000007016 153.0
SHD2_k127_6763876_7 Prokaryotic N-terminal methylation motif - - - 0.00000000000001213 81.0
SHD2_k127_6763876_8 general secretion pathway protein - - - 0.000000000008317 72.0
SHD2_k127_6763876_9 Aminotransferase class-III K00833 - 2.6.1.62 0.00000000318 58.0
SHD2_k127_67650_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.612e-228 727.0
SHD2_k127_67650_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 452.0
SHD2_k127_67650_2 Tetraprenyl-beta-curcumene synthase K16188 - 4.2.3.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 413.0
SHD2_k127_67650_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 306.0
SHD2_k127_67650_4 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002092 220.0
SHD2_k127_67650_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000001105 155.0
SHD2_k127_67650_6 Redoxin - - - 0.0000000000000000000000000000000000004649 143.0
SHD2_k127_67650_7 Pathogenicity locus - - - 0.0000000000001761 74.0
SHD2_k127_67650_8 Redoxin - - - 0.0000000001112 64.0
SHD2_k127_6775169_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
SHD2_k127_6775169_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 353.0
SHD2_k127_6775169_2 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003967 290.0
SHD2_k127_6775169_3 RNA polymerase sigma factor K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004099 276.0
SHD2_k127_6789702_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 1.437e-268 863.0
SHD2_k127_6789702_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 481.0
SHD2_k127_6789702_10 COG NOG19114 non supervised orthologous group - - - 0.0000000000000009257 81.0
SHD2_k127_6789702_11 gas vesicle protein - - - 0.000000000000008844 79.0
SHD2_k127_6789702_12 gas vesicle protein - - - 0.00000000004365 66.0
SHD2_k127_6789702_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 332.0
SHD2_k127_6789702_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 314.0
SHD2_k127_6789702_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 286.0
SHD2_k127_6789702_5 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008614 277.0
SHD2_k127_6789702_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000183 195.0
SHD2_k127_6789702_7 TIGRFAM RecB family nuclease - - - 0.000000000000000000000000000000000000000002801 173.0
SHD2_k127_6789702_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000006089 172.0
SHD2_k127_6789702_9 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000002364 98.0
SHD2_k127_6791138_0 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 9.421e-295 942.0
SHD2_k127_6791138_1 UvrD/REP helicase N-terminal domain K03582,K16898 - 3.1.11.5,3.6.4.12 4.294e-281 906.0
SHD2_k127_6791138_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 556.0
SHD2_k127_6791138_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 405.0
SHD2_k127_6791138_4 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 353.0
SHD2_k127_6791138_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000003684 115.0
SHD2_k127_6796701_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 5.927e-205 646.0
SHD2_k127_6796701_1 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007282 273.0
SHD2_k127_6796701_2 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000006817 188.0
SHD2_k127_6816304_0 radical SAM domain protein K22318 - - 1.976e-196 629.0
SHD2_k127_6816304_1 Domain of unknown function (DUF1846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 514.0
SHD2_k127_6816304_10 CopG domain protein DNA-binding domain protein K18918 - - 0.00003106 49.0
SHD2_k127_6816304_11 - - - - 0.0008481 45.0
SHD2_k127_6816304_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 372.0
SHD2_k127_6816304_3 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 322.0
SHD2_k127_6816304_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 319.0
SHD2_k127_6816304_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
SHD2_k127_6816304_6 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004841 276.0
SHD2_k127_6816304_7 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000001103 125.0
SHD2_k127_6816304_8 nuclease activity K06218 - - 0.0000000000000000000006636 96.0
SHD2_k127_6816304_9 Y_Y_Y domain - - - 0.000000000928 72.0
SHD2_k127_6844371_0 cell redox homeostasis - - - 2.713e-214 675.0
SHD2_k127_6844371_1 PFAM Acetyl-CoA hydrolase transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 577.0
SHD2_k127_6844371_10 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001231 286.0
SHD2_k127_6844371_11 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006938 258.0
SHD2_k127_6844371_12 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000001483 241.0
SHD2_k127_6844371_13 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000003439 238.0
SHD2_k127_6844371_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000004015 195.0
SHD2_k127_6844371_15 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000006837 147.0
SHD2_k127_6844371_16 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.0000000000000000000000000003425 119.0
SHD2_k127_6844371_17 Haemolytic - - - 0.000000000000000000001155 100.0
SHD2_k127_6844371_18 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000000216 91.0
SHD2_k127_6844371_19 Cytochrome c3 - - - 0.0000000005509 65.0
SHD2_k127_6844371_2 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 542.0
SHD2_k127_6844371_20 - - - - 0.00001032 50.0
SHD2_k127_6844371_21 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0001944 45.0
SHD2_k127_6844371_3 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 507.0
SHD2_k127_6844371_4 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 493.0
SHD2_k127_6844371_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 485.0
SHD2_k127_6844371_6 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 470.0
SHD2_k127_6844371_7 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 341.0
SHD2_k127_6844371_8 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 341.0
SHD2_k127_6844371_9 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 308.0
SHD2_k127_689030_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 8.298e-237 746.0
SHD2_k127_689030_1 Aminotransferase class I and II - - - 5.53e-220 690.0
SHD2_k127_689030_10 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 310.0
SHD2_k127_689030_11 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 293.0
SHD2_k127_689030_12 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 287.0
SHD2_k127_689030_13 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006158 279.0
SHD2_k127_689030_14 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
SHD2_k127_689030_15 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000171 279.0
SHD2_k127_689030_16 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007209 250.0
SHD2_k127_689030_17 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000005513 232.0
SHD2_k127_689030_18 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000006327 190.0
SHD2_k127_689030_19 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000003772 173.0
SHD2_k127_689030_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.206e-199 632.0
SHD2_k127_689030_20 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000002439 154.0
SHD2_k127_689030_21 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001576 147.0
SHD2_k127_689030_22 TonB C terminal K03832 - - 0.0000000000000000000008007 102.0
SHD2_k127_689030_23 phenylacetic acid degradation protein K02614 - - 0.0000000006524 66.0
SHD2_k127_689030_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.521e-196 626.0
SHD2_k127_689030_4 Pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 529.0
SHD2_k127_689030_5 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 493.0
SHD2_k127_689030_6 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 453.0
SHD2_k127_689030_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 443.0
SHD2_k127_689030_8 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
SHD2_k127_689030_9 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 368.0
SHD2_k127_6895332_0 AAA domain K07028 - - 6.414e-200 637.0
SHD2_k127_6895332_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 581.0
SHD2_k127_6895332_10 ABC-type multidrug transport system, ATPase and permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 352.0
SHD2_k127_6895332_11 Electron transfer flavoprotein, beta K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 288.0
SHD2_k127_6895332_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001576 280.0
SHD2_k127_6895332_13 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
SHD2_k127_6895332_14 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004814 271.0
SHD2_k127_6895332_15 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000001612 246.0
SHD2_k127_6895332_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000002103 214.0
SHD2_k127_6895332_17 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000004417 196.0
SHD2_k127_6895332_18 - - - - 0.0000000000000000000000000000000000000000000000000006835 195.0
SHD2_k127_6895332_19 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000001357 187.0
SHD2_k127_6895332_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 565.0
SHD2_k127_6895332_20 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000002256 182.0
SHD2_k127_6895332_21 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000001287 178.0
SHD2_k127_6895332_22 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000006997 145.0
SHD2_k127_6895332_23 - - - - 0.0000000000000000000000000000000000003081 146.0
SHD2_k127_6895332_24 smart pdz dhr glgf - - - 0.0000000000000000000000000000000007446 149.0
SHD2_k127_6895332_25 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000003138 128.0
SHD2_k127_6895332_26 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.00000000000000000000000000001787 123.0
SHD2_k127_6895332_27 PFAM coenzyme PQQ synthesis - - - 0.0000000000000000000000000001121 120.0
SHD2_k127_6895332_28 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000001474 106.0
SHD2_k127_6895332_3 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 564.0
SHD2_k127_6895332_4 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 484.0
SHD2_k127_6895332_5 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 479.0
SHD2_k127_6895332_6 radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 477.0
SHD2_k127_6895332_7 Iron-containing alcohol dehydrogenase K00001,K00100,K08325,K19955 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 424.0
SHD2_k127_6895332_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 365.0
SHD2_k127_6895332_9 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 346.0
SHD2_k127_6927886_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 364.0
SHD2_k127_6927886_1 PFAM Iron-containing alcohol dehydrogenase K00001,K19954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 365.0
SHD2_k127_6927886_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 310.0
SHD2_k127_6927886_3 PFAM ParB domain protein nuclease K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000007083 242.0
SHD2_k127_6927886_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000001044 155.0
SHD2_k127_6933134_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.0 1966.0
SHD2_k127_6933134_1 Alcohol dehydrogenase GroES-like domain K13979 - - 9.253e-205 639.0
SHD2_k127_6933134_2 AraC-type transcriptional regulator N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
SHD2_k127_6933134_3 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 348.0
SHD2_k127_6933134_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008216 227.0
SHD2_k127_6933134_5 Flavodoxin - - - 0.000000000000000000000000000000000000000001977 164.0
SHD2_k127_6933134_6 Starch synthase catalytic domain - - - 0.0000000000000000000000007167 105.0
SHD2_k127_6933134_7 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000001136 104.0
SHD2_k127_6959623_0 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 582.0
SHD2_k127_6959623_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 503.0
SHD2_k127_6959623_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000006443 170.0
SHD2_k127_6959623_11 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000003383 111.0
SHD2_k127_6959623_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 423.0
SHD2_k127_6959623_3 Pfam:AHS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 332.0
SHD2_k127_6959623_4 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 307.0
SHD2_k127_6959623_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 293.0
SHD2_k127_6959623_6 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005692 282.0
SHD2_k127_6959623_7 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000008424 262.0
SHD2_k127_6959623_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 261.0
SHD2_k127_6959623_9 Pfam:AHS1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001267 255.0
SHD2_k127_697651_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 562.0
SHD2_k127_697651_1 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000002332 151.0
SHD2_k127_697651_2 phosphate acetyltransferase K00634,K13788 - 2.3.1.19,2.3.1.8 0.00000000000000000002618 94.0
SHD2_k127_6991146_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 581.0
SHD2_k127_6991146_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 574.0
SHD2_k127_6991146_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 455.0
SHD2_k127_6991146_3 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 314.0
SHD2_k127_6991146_4 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000000000000000000000000000000006016 184.0
SHD2_k127_7001571_0 2 heme-binding sites K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 507.0
SHD2_k127_7001571_1 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 422.0
SHD2_k127_7001571_2 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000005041 162.0
SHD2_k127_7045626_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 379.0
SHD2_k127_7045626_1 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000002327 214.0
SHD2_k127_7062755_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1131.0
SHD2_k127_7062755_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.063e-318 987.0
SHD2_k127_7062755_10 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005941 285.0
SHD2_k127_7062755_11 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
SHD2_k127_7062755_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000004568 210.0
SHD2_k127_7062755_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001795 200.0
SHD2_k127_7062755_14 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000001283 174.0
SHD2_k127_7062755_15 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000001378 176.0
SHD2_k127_7062755_16 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000001974 171.0
SHD2_k127_7062755_17 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000000000001514 150.0
SHD2_k127_7062755_2 Short chain fatty acid transporter K02106 - - 6.003e-204 644.0
SHD2_k127_7062755_20 Bacteriophage replication gene A protein (GPA) - - - 0.000786 45.0
SHD2_k127_7062755_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 571.0
SHD2_k127_7062755_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 494.0
SHD2_k127_7062755_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 464.0
SHD2_k127_7062755_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 441.0
SHD2_k127_7062755_7 PFAM metal-dependent phosphohydrolase, HD sub domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 298.0
SHD2_k127_7062755_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 302.0
SHD2_k127_7062755_9 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 296.0
SHD2_k127_71708_0 PFAM ABC transporter related - - - 2.33e-279 865.0
SHD2_k127_71708_1 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 5.106e-277 857.0
SHD2_k127_71708_10 Putative exonuclease, RdgC K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 404.0
SHD2_k127_71708_11 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 378.0
SHD2_k127_71708_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 328.0
SHD2_k127_71708_13 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 319.0
SHD2_k127_71708_14 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 321.0
SHD2_k127_71708_15 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 316.0
SHD2_k127_71708_16 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 315.0
SHD2_k127_71708_17 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 303.0
SHD2_k127_71708_18 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 299.0
SHD2_k127_71708_19 PFAM ABC transporter related K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002154 284.0
SHD2_k127_71708_2 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 5.658e-216 684.0
SHD2_k127_71708_20 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
SHD2_k127_71708_21 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002072 254.0
SHD2_k127_71708_22 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000004786 247.0
SHD2_k127_71708_23 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000001456 243.0
SHD2_k127_71708_24 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000000000000000003689 241.0
SHD2_k127_71708_25 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000001611 228.0
SHD2_k127_71708_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000007966 230.0
SHD2_k127_71708_27 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000001931 214.0
SHD2_k127_71708_28 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000001236 194.0
SHD2_k127_71708_29 iron ion homeostasis K03709,K04758 - - 0.00000000000000000000000000000000000000000000001022 183.0
SHD2_k127_71708_3 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 611.0
SHD2_k127_71708_30 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000001891 173.0
SHD2_k127_71708_31 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000003245 146.0
SHD2_k127_71708_32 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000002514 135.0
SHD2_k127_71708_33 SMART Cold shock protein K03704 - - 0.000000000000000000000000000002824 123.0
SHD2_k127_71708_34 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000007017 106.0
SHD2_k127_71708_35 - - - - 0.0000000000000000000000007349 106.0
SHD2_k127_71708_36 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000004235 108.0
SHD2_k127_71708_38 Belongs to the Fur family K03711 - - 0.000000000000000003447 90.0
SHD2_k127_71708_39 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000004346 71.0
SHD2_k127_71708_4 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 546.0
SHD2_k127_71708_5 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 540.0
SHD2_k127_71708_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 543.0
SHD2_k127_71708_7 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 504.0
SHD2_k127_71708_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 479.0
SHD2_k127_71708_9 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 449.0
SHD2_k127_7194410_0 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 387.0
SHD2_k127_7194410_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002661 276.0
SHD2_k127_7194410_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000003564 162.0
SHD2_k127_7194410_3 - - - - 0.0000000000000000000000000000000000015 157.0
SHD2_k127_7194410_4 - - - - 0.00000000000000000207 90.0
SHD2_k127_7266982_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.251e-293 915.0
SHD2_k127_7266982_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 458.0
SHD2_k127_7266982_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000005325 180.0
SHD2_k127_7285388_0 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008385 257.0
SHD2_k127_7285388_1 KaiB K08481 - - 0.00000000000000000000000000000000007546 135.0
SHD2_k127_7285388_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000002434 130.0
SHD2_k127_7285388_3 Histidine kinase K07778 - 2.7.13.3 0.000000000000000000000000008511 128.0
SHD2_k127_7363519_0 ABC transporter K15738 - - 9.311e-289 899.0
SHD2_k127_7363519_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.592e-274 863.0
SHD2_k127_7363519_10 - - - - 0.0000000000000000000000000000000000000000000008083 169.0
SHD2_k127_7363519_11 Membrane dipeptidase (Peptidase family M19) - - - 0.0000000000000000000000000000000242 139.0
SHD2_k127_7363519_12 SMART Cold shock protein K03704 - - 0.000000000000000000000000000004551 120.0
SHD2_k127_7363519_14 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000001111 103.0
SHD2_k127_7363519_15 YCII-related domain K03652 - 3.2.2.21 0.0000000000000000000001482 101.0
SHD2_k127_7363519_16 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000001757 96.0
SHD2_k127_7363519_2 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 617.0
SHD2_k127_7363519_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 542.0
SHD2_k127_7363519_4 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 419.0
SHD2_k127_7363519_5 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 351.0
SHD2_k127_7363519_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000007869 230.0
SHD2_k127_7363519_7 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
SHD2_k127_7363519_8 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
SHD2_k127_7363519_9 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.000000000000000000000000000000000000000000000219 171.0
SHD2_k127_736632_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 511.0
SHD2_k127_736632_1 - - - - 0.0001095 50.0
SHD2_k127_7397648_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1800.0
SHD2_k127_7397648_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1174.0
SHD2_k127_7397648_10 META domain - - - 0.000000000000003431 82.0
SHD2_k127_7397648_11 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000007 65.0
SHD2_k127_7397648_12 - - - - 0.000009668 53.0
SHD2_k127_7397648_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 7.908e-210 662.0
SHD2_k127_7397648_3 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 431.0
SHD2_k127_7397648_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 410.0
SHD2_k127_7397648_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 333.0
SHD2_k127_7397648_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 328.0
SHD2_k127_7397648_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 319.0
SHD2_k127_7397648_8 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000001525 188.0
SHD2_k127_7397648_9 photosystem II stabilization K02237,K02238,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000003256 97.0
SHD2_k127_7404131_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.654e-276 863.0
SHD2_k127_7404131_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.155e-247 774.0
SHD2_k127_7404131_10 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 361.0
SHD2_k127_7404131_11 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 312.0
SHD2_k127_7404131_12 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 301.0
SHD2_k127_7404131_13 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005082 270.0
SHD2_k127_7404131_14 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001533 267.0
SHD2_k127_7404131_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006452 265.0
SHD2_k127_7404131_16 - - - - 0.0000000000000000000000000000000000000000000000000000000007641 209.0
SHD2_k127_7404131_17 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000001205 183.0
SHD2_k127_7404131_18 YacP-like NYN domain K06962 - - 0.000000000000000000000000000000000000000000000004636 179.0
SHD2_k127_7404131_19 4Fe-4S binding domain K00171 - 1.2.7.1 0.00000000000000000000000000000000006264 139.0
SHD2_k127_7404131_2 Acetyl-CoA hydrolase transferase N-terminal domain - - - 1.388e-234 741.0
SHD2_k127_7404131_20 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000726 125.0
SHD2_k127_7404131_21 Regulatory protein, FmdB family - - - 0.00000023 55.0
SHD2_k127_7404131_3 4Fe-4S dicluster domain - - - 1.601e-210 675.0
SHD2_k127_7404131_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 543.0
SHD2_k127_7404131_5 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 502.0
SHD2_k127_7404131_6 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
SHD2_k127_7404131_7 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 393.0
SHD2_k127_7404131_8 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 393.0
SHD2_k127_7404131_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 389.0
SHD2_k127_7413229_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1678.0
SHD2_k127_7413229_1 GXGXG motif - - - 0.0 1056.0
SHD2_k127_7413229_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.000000000002633 70.0
SHD2_k127_7413229_11 Dihydrodipicolinate reductase, C-terminus K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0006339 46.0
SHD2_k127_7413229_2 4Fe-4S double cluster binding domain K00265 - 1.4.1.13,1.4.1.14 1.745e-279 863.0
SHD2_k127_7413229_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.154e-229 718.0
SHD2_k127_7413229_4 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 5.854e-226 708.0
SHD2_k127_7413229_5 Ammonium Transporter K03320 - - 3.223e-209 655.0
SHD2_k127_7413229_6 Ammonium Transporter K03320 - - 7.391e-198 624.0
SHD2_k127_7413229_7 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 529.0
SHD2_k127_7413229_8 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000009327 191.0
SHD2_k127_7413229_9 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000002796 166.0
SHD2_k127_7414758_0 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 460.0
SHD2_k127_7414758_1 Psort location Cytoplasmic, score K00048 - 1.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000006089 270.0
SHD2_k127_7416212_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 402.0
SHD2_k127_7416212_2 - - - - 0.000000000000000000000000000000000000000000001099 169.0
SHD2_k127_7416212_3 PilZ domain - - - 0.0000000000000000000136 102.0
SHD2_k127_7416212_4 translation initiation factor activity K06996 - - 0.0000002052 55.0
SHD2_k127_7447142_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1721.0
SHD2_k127_7447142_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 1.155e-205 646.0
SHD2_k127_7447142_10 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
SHD2_k127_7447142_11 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009764 282.0
SHD2_k127_7447142_12 Tetracycline repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 244.0
SHD2_k127_7447142_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000004298 177.0
SHD2_k127_7447142_14 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000000000000000000000000000001842 137.0
SHD2_k127_7447142_15 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000000003267 130.0
SHD2_k127_7447142_16 Universal stress protein family - - - 0.000000000000000000000000005366 116.0
SHD2_k127_7447142_17 domain protein K20276 - - 0.000000001473 67.0
SHD2_k127_7447142_2 PFAM Acyl-CoA dehydrogenase K00249,K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 593.0
SHD2_k127_7447142_3 PFAM Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 566.0
SHD2_k127_7447142_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 529.0
SHD2_k127_7447142_5 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 467.0
SHD2_k127_7447142_6 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 405.0
SHD2_k127_7447142_7 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K15327,K15329,K15469 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 387.0
SHD2_k127_7447142_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 329.0
SHD2_k127_7447142_9 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 313.0
SHD2_k127_7448476_0 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000001007 263.0
SHD2_k127_7448476_1 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008016 261.0
SHD2_k127_7448476_2 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000001109 232.0
SHD2_k127_7501379_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 612.0
SHD2_k127_7501379_1 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000002997 237.0
SHD2_k127_7501379_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000001648 160.0
SHD2_k127_7501379_3 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000001363 130.0
SHD2_k127_7510445_0 - - - - 0.000000000000000000000000000000000000000000000000000000000003876 218.0
SHD2_k127_7510445_1 Thioesterase superfamily - - - 0.00000000000000000000001133 105.0
SHD2_k127_7510445_2 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA K11935 - - 0.000000000000001645 89.0
SHD2_k127_7533896_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 9.78e-261 816.0
SHD2_k127_7533896_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.275e-219 691.0
SHD2_k127_7533896_10 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008045 251.0
SHD2_k127_7533896_11 Glycosyltransferase Family 4 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000002304 229.0
SHD2_k127_7533896_12 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000377 198.0
SHD2_k127_7533896_13 PFAM glycosyl transferase, family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000001159 205.0
SHD2_k127_7533896_14 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000001022 140.0
SHD2_k127_7533896_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000003493 118.0
SHD2_k127_7533896_16 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000005909 100.0
SHD2_k127_7533896_17 Plasmid stability protein K21495 - - 0.0000000000001209 74.0
SHD2_k127_7533896_18 PFAM oxidoreductase domain protein K09949 - - 0.0004827 44.0
SHD2_k127_7533896_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 443.0
SHD2_k127_7533896_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 376.0
SHD2_k127_7533896_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 344.0
SHD2_k127_7533896_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 320.0
SHD2_k127_7533896_6 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 305.0
SHD2_k127_7533896_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004881 276.0
SHD2_k127_7533896_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006552 275.0
SHD2_k127_7533896_9 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000002131 269.0
SHD2_k127_7583733_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1096.0
SHD2_k127_7583733_1 General secretory system II protein E domain protein - - - 0.0 1018.0
SHD2_k127_7583733_2 aconitate hydratase K01681 - 4.2.1.3 7.676e-289 899.0
SHD2_k127_7583733_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 544.0
SHD2_k127_7583733_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 442.0
SHD2_k127_7583733_5 Type II secretory pathway component ExeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 292.0
SHD2_k127_7583733_6 PFAM Membrane protein of K08972 - - 0.000000000000000000000000000000002148 134.0
SHD2_k127_7583733_7 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000000001056 110.0
SHD2_k127_7583733_8 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.0000000000000002443 83.0
SHD2_k127_7583733_9 Protein of unknown function (DUF1698) - - - 0.00000000000335 76.0
SHD2_k127_7589797_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.055e-290 904.0
SHD2_k127_7589797_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 567.0
SHD2_k127_7589797_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 565.0
SHD2_k127_7589797_3 Bacterial regulatory protein, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 470.0
SHD2_k127_7589797_4 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 450.0
SHD2_k127_7590115_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 524.0
SHD2_k127_7590115_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 530.0
SHD2_k127_7590115_10 PFAM Rubrerythrin - - - 0.000000000000008603 80.0
SHD2_k127_7590115_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000001408 74.0
SHD2_k127_7590115_12 Protein of Unknown function (DUF2784) - - - 0.000000003693 64.0
SHD2_k127_7590115_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 464.0
SHD2_k127_7590115_3 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
SHD2_k127_7590115_4 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 333.0
SHD2_k127_7590115_5 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
SHD2_k127_7590115_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000001061 256.0
SHD2_k127_7590115_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000003044 239.0
SHD2_k127_7590115_8 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000001201 237.0
SHD2_k127_7590115_9 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000000002097 179.0
SHD2_k127_7634123_0 von Willebrand factor type A domain - - - 0.0 1223.0
SHD2_k127_7634123_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1054.0
SHD2_k127_7634123_10 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
SHD2_k127_7634123_11 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 303.0
SHD2_k127_7634123_12 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008012 269.0
SHD2_k127_7634123_13 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000001279 178.0
SHD2_k127_7634123_14 Universal stress protein family - - - 0.0000000000000000000000000000000000001392 146.0
SHD2_k127_7634123_15 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000000003913 136.0
SHD2_k127_7634123_17 O-methyltransferase - - - 0.0000000000000000000000000000001478 133.0
SHD2_k127_7634123_18 Histidine kinase - - - 0.00000000000000000000000000001277 139.0
SHD2_k127_7634123_19 SMART Cold shock protein K03704 - - 0.00000000000000000000000000001327 118.0
SHD2_k127_7634123_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 550.0
SHD2_k127_7634123_20 Histidine kinase - - - 0.00000000000000000000000001227 130.0
SHD2_k127_7634123_21 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000002047 103.0
SHD2_k127_7634123_22 Undecaprenyl-phosphate galactose phosphotransferase - - - 0.00000000000000003665 89.0
SHD2_k127_7634123_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 426.0
SHD2_k127_7634123_4 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 422.0
SHD2_k127_7634123_5 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 403.0
SHD2_k127_7634123_6 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 448.0
SHD2_k127_7634123_7 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 370.0
SHD2_k127_7634123_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 359.0
SHD2_k127_7634123_9 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 346.0
SHD2_k127_7634243_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 512.0
SHD2_k127_7634243_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 472.0
SHD2_k127_7634243_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 442.0
SHD2_k127_7634243_3 PFAM ABC transporter K01990,K01992,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 383.0
SHD2_k127_7634243_4 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 332.0
SHD2_k127_7634243_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004926 277.0
SHD2_k127_7634243_6 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000001419 183.0
SHD2_k127_7663276_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.717e-248 771.0
SHD2_k127_7663276_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.266e-231 727.0
SHD2_k127_7663276_10 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000006601 183.0
SHD2_k127_7663276_11 - - - - 0.000000000000000000000000000000000000000000001843 169.0
SHD2_k127_7663276_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000001653 124.0
SHD2_k127_7663276_13 Universal stress protein family - - - 0.000000000000000448 84.0
SHD2_k127_7663276_2 Thymidylate synthase complementing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 591.0
SHD2_k127_7663276_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 548.0
SHD2_k127_7663276_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 483.0
SHD2_k127_7663276_5 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 456.0
SHD2_k127_7663276_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 396.0
SHD2_k127_7663276_7 Choline/ethanolamine kinase K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
SHD2_k127_7663276_8 Putative regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000006209 208.0
SHD2_k127_7663276_9 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000006116 183.0
SHD2_k127_7667970_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1617.0
SHD2_k127_7667970_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 1.799e-214 672.0
SHD2_k127_7667970_10 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 391.0
SHD2_k127_7667970_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 386.0
SHD2_k127_7667970_12 tRNA methyl transferase K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 381.0
SHD2_k127_7667970_13 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 357.0
SHD2_k127_7667970_14 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 351.0
SHD2_k127_7667970_15 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
SHD2_k127_7667970_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 339.0
SHD2_k127_7667970_17 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 297.0
SHD2_k127_7667970_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002082 291.0
SHD2_k127_7667970_19 TIGRFAM methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001722 250.0
SHD2_k127_7667970_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 544.0
SHD2_k127_7667970_20 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003438 246.0
SHD2_k127_7667970_21 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
SHD2_k127_7667970_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000001601 233.0
SHD2_k127_7667970_23 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000001498 224.0
SHD2_k127_7667970_24 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000001679 214.0
SHD2_k127_7667970_25 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000002713 197.0
SHD2_k127_7667970_26 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000302 177.0
SHD2_k127_7667970_27 Transcriptional regulator - - - 0.000000000000000000000000000000001029 135.0
SHD2_k127_7667970_28 Glutaredoxin - - - 0.0000000000000000000000000001972 117.0
SHD2_k127_7667970_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 538.0
SHD2_k127_7667970_4 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 507.0
SHD2_k127_7667970_5 cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 490.0
SHD2_k127_7667970_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 485.0
SHD2_k127_7667970_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 469.0
SHD2_k127_7667970_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 467.0
SHD2_k127_7667970_9 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 414.0
SHD2_k127_7679607_0 Amino acid permease - - - 3.734e-300 932.0
SHD2_k127_7679607_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.178e-279 866.0
SHD2_k127_7679607_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 548.0
SHD2_k127_7679607_3 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 293.0
SHD2_k127_7679607_4 Acetolactate synthase K01653,K16785 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000008209 72.0
SHD2_k127_7679607_5 methyltransferase - - - 0.00000001645 66.0
SHD2_k127_7754659_0 ABC transporter, transmembrane region K11004 - - 8.039e-261 822.0
SHD2_k127_7754659_1 PFAM secretion protein HlyD family protein K11003,K20345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 441.0
SHD2_k127_7754659_2 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001853 263.0
SHD2_k127_7754659_3 Hemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001767 225.0
SHD2_k127_7754659_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000004457 132.0
SHD2_k127_7796776_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 8.1e-208 656.0
SHD2_k127_7796776_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 501.0
SHD2_k127_7796776_10 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000009991 192.0
SHD2_k127_7796776_11 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000000000000000000000000000000000000000000000007475 178.0
SHD2_k127_7796776_12 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000000000000000000006926 141.0
SHD2_k127_7796776_13 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000003083 81.0
SHD2_k127_7796776_2 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 402.0
SHD2_k127_7796776_3 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 386.0
SHD2_k127_7796776_4 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
SHD2_k127_7796776_5 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 314.0
SHD2_k127_7796776_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 289.0
SHD2_k127_7796776_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000001691 221.0
SHD2_k127_7796776_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000002474 221.0
SHD2_k127_7796776_9 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000003701 203.0
SHD2_k127_7810101_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 497.0
SHD2_k127_7810101_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 408.0
SHD2_k127_7810101_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001087 222.0
SHD2_k127_7810101_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000002798 174.0
SHD2_k127_7810101_4 methyltransferase - - - 0.000000000000000000000000000000000000000004892 169.0
SHD2_k127_7810101_5 metal cluster binding K06940 - - 0.00000000000000000000000000000000001009 141.0
SHD2_k127_7813971_0 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008019 276.0
SHD2_k127_7813971_1 Belongs to the ompA family K03640 - - 0.000000000000000000000000007457 124.0
SHD2_k127_7813971_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000006711 107.0
SHD2_k127_7813971_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000005216 104.0
SHD2_k127_7837721_0 denitrification pathway - - - 1.175e-267 837.0
SHD2_k127_7837721_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 4.513e-196 620.0
SHD2_k127_7837721_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000341 269.0
SHD2_k127_7837721_11 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004019 246.0
SHD2_k127_7837721_12 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000005264 220.0
SHD2_k127_7837721_13 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000003781 209.0
SHD2_k127_7837721_14 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000002209 213.0
SHD2_k127_7837721_15 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.00000000000000000000000000000000000000000003916 168.0
SHD2_k127_7837721_16 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000001329 162.0
SHD2_k127_7837721_17 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000004674 152.0
SHD2_k127_7837721_18 - - - - 0.000000000000000000000000000002026 125.0
SHD2_k127_7837721_19 YCII-related domain K09780 - - 0.000000000000000000000000000003017 124.0
SHD2_k127_7837721_2 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 567.0
SHD2_k127_7837721_20 - - - - 0.000000000000000006918 89.0
SHD2_k127_7837721_21 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000001368 86.0
SHD2_k127_7837721_22 Haloacid dehalogenase-like hydrolase K07025,K18569 - - 0.00000000000000001817 90.0
SHD2_k127_7837721_23 LuxR family transcriptional regulator K04333,K20918 - - 0.00000000000000004368 91.0
SHD2_k127_7837721_24 - - - - 0.000000000001886 72.0
SHD2_k127_7837721_25 Sulphur transport K07112 - - 0.000000002856 58.0
SHD2_k127_7837721_26 Cold shock K03704 - - 0.000000004011 59.0
SHD2_k127_7837721_3 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 566.0
SHD2_k127_7837721_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 542.0
SHD2_k127_7837721_5 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 394.0
SHD2_k127_7837721_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 419.0
SHD2_k127_7837721_7 formate dehydrogenase K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 365.0
SHD2_k127_7837721_8 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000915 278.0
SHD2_k127_7837721_9 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 274.0
SHD2_k127_7844921_0 Bacterial protein of unknown function (DUF853) - - - 2.071e-211 664.0
SHD2_k127_7844921_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 401.0
SHD2_k127_7844921_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
SHD2_k127_7844921_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.000000000000000000000000000016 126.0
SHD2_k127_7844921_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000001704 127.0
SHD2_k127_7846860_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1132.0
SHD2_k127_7846860_1 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.0 1114.0
SHD2_k127_7846860_10 Thiamine-binding protein - - - 0.000000000000000000000000000000000000001632 149.0
SHD2_k127_7846860_11 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000001962 143.0
SHD2_k127_7846860_12 - - - - 0.00000000000000000000000000000000039 136.0
SHD2_k127_7846860_13 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000001301 121.0
SHD2_k127_7846860_14 redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000000009554 107.0
SHD2_k127_7846860_15 Thioesterase-like superfamily K15315 - - 0.00000000000007426 77.0
SHD2_k127_7846860_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 329.0
SHD2_k127_7846860_3 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 335.0
SHD2_k127_7846860_4 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 313.0
SHD2_k127_7846860_5 Chemotaxis phosphatase CheX K03409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 269.0
SHD2_k127_7846860_6 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002546 261.0
SHD2_k127_7846860_7 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 248.0
SHD2_k127_7846860_8 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000000368 231.0
SHD2_k127_7846860_9 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000005445 204.0
SHD2_k127_7869798_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 465.0
SHD2_k127_7869798_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 355.0
SHD2_k127_7869798_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006734 201.0
SHD2_k127_7869798_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000001617 182.0
SHD2_k127_7923_0 Cytochrome c554 and c-prime - - - 3.954e-310 968.0
SHD2_k127_7923_1 arylsulfatase A K01130 - 3.1.6.1 7.389e-278 862.0
SHD2_k127_7923_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000002099 140.0
SHD2_k127_7923_3 - - - - 0.00000000000000000000000001273 114.0
SHD2_k127_7923_4 Protein of unknown function (DUF1254) - - - 0.0000000000000001727 79.0
SHD2_k127_793352_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 460.0
SHD2_k127_793352_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 334.0
SHD2_k127_793352_2 DegT/DnrJ/EryC1/StrS aminotransferase family K19715 - 2.6.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
SHD2_k127_793352_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000009776 228.0
SHD2_k127_80021_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 4.112e-242 763.0
SHD2_k127_80021_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 488.0
SHD2_k127_80021_10 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000001339 130.0
SHD2_k127_80021_11 - - - - 0.00000000000000000003638 92.0
SHD2_k127_80021_12 mercury ion transmembrane transporter activity K07213,K08364 - - 0.000001046 54.0
SHD2_k127_80021_2 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 378.0
SHD2_k127_80021_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 370.0
SHD2_k127_80021_4 Bacterial extracellular solute-binding protein K10938 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 329.0
SHD2_k127_80021_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
SHD2_k127_80021_6 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000005147 177.0
SHD2_k127_80021_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000347 149.0
SHD2_k127_80021_8 translation initiation factor activity K06996 - - 0.000000000000000000000000000000008341 130.0
SHD2_k127_80021_9 - - - - 0.0000000000000000000000000000001005 128.0
SHD2_k127_803970_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 438.0
SHD2_k127_803970_1 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
SHD2_k127_803970_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000528 102.0
SHD2_k127_8065547_0 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 498.0
SHD2_k127_8065547_1 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 354.0
SHD2_k127_8065547_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 326.0
SHD2_k127_8065547_3 cellulose binding - - - 0.0000000000000000000000000000000000000000003279 170.0
SHD2_k127_8098640_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 560.0
SHD2_k127_8098640_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 354.0
SHD2_k127_8098640_2 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 300.0
SHD2_k127_8098640_3 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000001391 156.0
SHD2_k127_8119463_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1645.0
SHD2_k127_8119463_1 Glycogen debranching enzyme - - - 0.0 1319.0
SHD2_k127_8119463_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007965 285.0
SHD2_k127_8119463_11 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000005384 138.0
SHD2_k127_8119463_12 - - - - 0.0000000000000000000162 95.0
SHD2_k127_8119463_13 Glycine-zipper domain - - - 0.00000000000000000009855 91.0
SHD2_k127_8119463_2 Protein of unknown function (DUF3141) - - - 4.503e-244 777.0
SHD2_k127_8119463_3 Predicted membrane protein (DUF2254) - - - 2.315e-208 655.0
SHD2_k127_8119463_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 2.986e-196 623.0
SHD2_k127_8119463_5 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 509.0
SHD2_k127_8119463_6 phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 500.0
SHD2_k127_8119463_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 491.0
SHD2_k127_8119463_8 HlyD membrane-fusion protein of T1SS K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 492.0
SHD2_k127_8119463_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 349.0
SHD2_k127_8207030_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.324e-232 731.0
SHD2_k127_8207030_1 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 351.0
SHD2_k127_8207030_10 - - - - 0.000000001289 69.0
SHD2_k127_8207030_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00003138 53.0
SHD2_k127_8207030_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 308.0
SHD2_k127_8207030_3 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000007375 242.0
SHD2_k127_8207030_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000002473 228.0
SHD2_k127_8207030_5 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000953 202.0
SHD2_k127_8207030_6 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000447 157.0
SHD2_k127_8207030_7 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000001201 112.0
SHD2_k127_8223925_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 553.0
SHD2_k127_8223925_1 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 535.0
SHD2_k127_8223925_10 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000004706 145.0
SHD2_k127_8223925_11 RNA recognition motif - - - 0.0000000000000000000000000000000001297 136.0
SHD2_k127_8223925_12 FAD binding domain K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.000000000000000000000000000000001545 139.0
SHD2_k127_8223925_13 Protein of unknown function (DUF493) K09158 - - 0.00000000000000000004369 92.0
SHD2_k127_8223925_14 - - - - 0.0000000000003774 72.0
SHD2_k127_8223925_2 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 422.0
SHD2_k127_8223925_3 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 421.0
SHD2_k127_8223925_4 PFAM glycoside hydrolase family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 412.0
SHD2_k127_8223925_5 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 353.0
SHD2_k127_8223925_6 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001382 246.0
SHD2_k127_8223925_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000007891 191.0
SHD2_k127_8223925_8 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000962 183.0
SHD2_k127_8223925_9 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000001374 145.0
SHD2_k127_8233085_0 transporter, DctM subunit K11690 - - 2.293e-197 625.0
SHD2_k127_8233085_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 546.0
SHD2_k127_8233085_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 547.0
SHD2_k127_8233085_3 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 427.0
SHD2_k127_8233085_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 417.0
SHD2_k127_8233085_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000005078 230.0
SHD2_k127_8233085_6 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000003379 177.0
SHD2_k127_8233085_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000006954 137.0
SHD2_k127_8233085_8 PAS fold - - - 0.000000000000000000000000000001036 132.0
SHD2_k127_8243942_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K11529,K15893 - 1.1.1.26,2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 465.0
SHD2_k127_8243942_1 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000009634 225.0
SHD2_k127_8243942_2 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000001536 96.0
SHD2_k127_8262476_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 4.813e-220 686.0
SHD2_k127_8262476_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 535.0
SHD2_k127_8262476_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000007822 48.0
SHD2_k127_8276419_0 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 349.0
SHD2_k127_8276419_1 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 334.0
SHD2_k127_8276419_2 Flagellar hook capping protein - N-terminal region K02389 - - 0.000000000000000000000000000000000000000000001827 173.0
SHD2_k127_8276419_4 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000153 125.0
SHD2_k127_8276419_5 bacterial-type flagellum assembly K02414 - - 0.0000000000000001642 93.0
SHD2_k127_8276419_6 bacterial-type flagellum organization K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0007132 48.0
SHD2_k127_8289472_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 584.0
SHD2_k127_831055_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703,K01176 - 2.4.1.21,3.2.1.1 0.0 1157.0
SHD2_k127_831055_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 409.0
SHD2_k127_831055_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000276 247.0
SHD2_k127_831055_3 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000003629 212.0
SHD2_k127_836813_0 Belongs to the thiolase family K00626 - 2.3.1.9 8.286e-204 640.0
SHD2_k127_836813_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 1.895e-198 629.0
SHD2_k127_836813_10 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004164 271.0
SHD2_k127_836813_11 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001142 237.0
SHD2_k127_836813_12 Psort location CytoplasmicMembrane, score 10.00 K07052 - - 0.000000000000000000000000000000000000000000000000000002939 198.0
SHD2_k127_836813_13 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000004282 196.0
SHD2_k127_836813_14 lipid binding K03098 - - 0.00000000000000000000000000000000000000000000007747 175.0
SHD2_k127_836813_16 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000002524 115.0
SHD2_k127_836813_17 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000001447 119.0
SHD2_k127_836813_18 - - - - 0.00000000000000000001318 97.0
SHD2_k127_836813_19 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K12276 - - 0.0000000001282 70.0
SHD2_k127_836813_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 597.0
SHD2_k127_836813_20 - - - - 0.000000006301 65.0
SHD2_k127_836813_3 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 579.0
SHD2_k127_836813_4 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 494.0
SHD2_k127_836813_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 404.0
SHD2_k127_836813_6 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 414.0
SHD2_k127_836813_7 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 336.0
SHD2_k127_836813_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 331.0
SHD2_k127_836813_9 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 336.0
SHD2_k127_842537_0 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 538.0
SHD2_k127_842537_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 332.0
SHD2_k127_842537_2 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000003218 210.0
SHD2_k127_842537_3 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000001242 111.0
SHD2_k127_842537_4 granule-associated protein - - - 0.000000384 58.0
SHD2_k127_870868_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 4.699e-219 696.0
SHD2_k127_870868_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 408.0
SHD2_k127_870868_2 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 389.0
SHD2_k127_870868_3 lactate oxidation K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009352 274.0
SHD2_k127_870868_4 4Fe-4S binding domain K02573 - - 0.000000000000000000000000000000000000000000000000000000000001083 217.0
SHD2_k127_870868_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000006124 165.0
SHD2_k127_870868_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000004739 109.0
SHD2_k127_872442_0 FhlB domain-containing protein K04061 - - 0.0000000000000000000000003884 108.0
SHD2_k127_872442_1 Belongs to the flagella basal body rod proteins family K02391 - - 0.00000000000000000001728 99.0
SHD2_k127_872442_2 Flagellar hook-length control protein FliK - - - 0.0000009442 61.0
SHD2_k127_95638_0 VWA containing CoxE family protein K09989 - - 1.006e-196 621.0
SHD2_k127_95638_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
SHD2_k127_95638_2 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 382.0
SHD2_k127_95638_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 355.0